Stéphane Hunot

Publications

Article dans une revue (26)

DRD2 activation inhibits choroidal neovascularization in patients with Parkinson’s disease and age-related macular degeneration Thibaud Mathis,Florian Baudin,Anne-Sophie Mariet,Sébastien Augustin,Marion Bricoutet al. The Journal of clinical investigation, 2024, 134 (17), pp.e174199. ⟨10.1172/JCI174199⟩ Article dans une revue hal-04667733v1
Parkinson’s disease-derived α-synuclein assemblies combined with chronic-type inflammatory cues promote a neurotoxic microglial phenotype Cansu Yildirim-Balatan,Alexis Fenyi,Pierre Besnault,Lina Gomez,Julia E Sepulveda-Diazet al. Journal of Neuroinflammation, 2024, 21 (54), ⟨10.1186/s12974-024-03043-5⟩ Article dans une revue hal-04472638v1
The Pesticide Chlordecone Promotes Parkinsonism-like Neurodegeneration with Tau Lesions in Midbrain Cultures and C. elegans Worms Valeria Parrales-Macias,Patrick Pierre Michel,Aurore Tourville,Rita Raisman-Vozari,Stéphane Haïket al. Cells, 2023, 12 (9), pp.1336. ⟨10.3390/cells12091336⟩ Article dans une revue hal-04091344v1
Author Correction: Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease Carmen Noelker,Lydie Morel,Thomas Lescot,Anke Osterloh,Daniel Alvarez-Fischeret al. Scientific Reports, 2023, 13 (1), pp.826. ⟨10.1038/s41598-022-26917-1⟩ Article dans une revue hal-04785385v1
Modelling $\alpha$-synuclein aggregation and neurodegeneration with fibril seeds in primary cultures of mouse dopaminergic neurons Aurore Tourville,David Akbar,Olga Corti,Jochen H. M. Prehn,Ronald Melkiet al. Cells, 2022, 11 (10), pp.1640. ⟨10.3390/cells11101640⟩ Article dans une revue cea-03683729v1
Editorial: Brain-Targeted Autoimmunity: Beyond Multiple Sclerosis Serge Nataf,Stéphane Hunot,Guillaume Dorothée,Roland Liblau Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.677577⟩ Article dans une revue hal-03190313v1
Glucocorticoid receptor in astrocytes regulates midbrain dopamine neurodegeneration through connexin hemichannel activity Layal Maatouk,Chenju Yi,Maria-Angeles Carrillo-de Sauvage,Anne-Claire Compagnion,Stéphane Hunotet al. Cell Death and Differentiation, 2019, 26, pp.580-596. ⟨10.1038/s41418-018-0150-3⟩ Article dans une revue hal-01900936v1
Analysis of monocyte infiltration in MPTP mice reveals that microglial CX3CR1 protects against neurotoxic over-induction of monocyte-attracting CCL2 by astrocytes Vincent R. Parillaud,Guillaume Lornet,Yann Monnet,Anne-Laure Privat,Andrei T. Haddadet al. Journal of Neuroinflammation, 2017, 14 (1), pp.60. ⟨10.1186/s12974-017-0830-9⟩ Article dans une revue inserm-01493135v1
Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy Cyril Laurent,Guillaume Dorothee,Stéphane Hunot,Elodie Martin,Yann Monnetet al. Brain - A Journal of Neurology , 2017, 140 (1), pp.184 - 200. ⟨10.1093/brain/aww270⟩ Article dans une revue inserm-01833350v1
Neutral Sphingomyelinase Behaviour in Hippocampus Neuroinflammation of MPTP-Induced Mouse Model of Parkinson’s Disease and in Embryonic Hippocampal Cells Samuela Cataldi,Cataldo Arcuri,Stéphane Hunot,François-Pierre Légeron,Carmen Meccaet al. Mediators of Inflammation, 2017, 2017, pp.2470950. ⟨10.1155/2017/2470950⟩ Article dans une revue hal-04406304v1
Tau et troubles cognitifs Cyril Laurent,Guillaume Dorothee,Stéphane Hunot,Elodie Martin,Cecile Delarasseet al. Médecine/Sciences, 2017, 33 (10), pp.817 - 819. ⟨10.1051/medsci/20173310002⟩ Article dans une revue inserm-01833339v1
Legionella pneumophila Strain 130b Evades Macrophage Cell Death Independent of the Effector SidF in the Absence of Flagellin Mary A Speir,Adam A Vogrin,Azadeh A Seidi,Gilu A Abraham,Stéphane A Hunotet al. Frontiers in Cellular and Infection Microbiology, 2017, 7, pp.35. ⟨10.3389/fcimb.2017.00035⟩ Article dans une revue hal-01488121v1
e-Cadherin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson Disease Samuela Cataldi,Michela Codini,Stéphane Hunot,François-Pierre Légeron,Ivana Ferriet al. Mediators of Inflammation, 2016, pp.3937057. ⟨10.1155/2016/3937057⟩ Article dans une revue hal-01323849v1
Understanding Dopaminergic Cell Death Pathways in Parkinson Disease Patrick P. Michel,Etienne Hirsch,Stéphane Hunot Neuron, 2016, 90 ((4)), pp.675-91. ⟨10.1016/j.neuron.2016.03.038⟩ Article dans une revue inserm-01348875v1
Neuroinflammation in Alzheimer's disease Michael T Heneka,Monica J Carson,Joseph El Khoury,Gary E Landreth,Frederic Brosseronet al. The Lancet Neurology, 2015, 14 (4), ⟨10.1016/S1474-4422(15)70016-5⟩ Article dans une revue hal-04785384v1
Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations Benjamin Dehay,Mathieu Bourdenx,Philippe Gorry,Serge Przedborski,Miquel Vilaet al. The Lancet Neurology, 2015, 14 (8), pp.855-866. ⟨10.1016/S1474-4422(15)00006-X⟩ Article dans une revue inserm-02439371v1
Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease Carmen Noelker,Lydie Morel,Anke Osterloh,Daniel Alvarez-Fischer,Thomas Lescotet al. Journal of Neuroinflammation, 2014, 11 (1), pp.86 Article dans une revue inserm-00990645v1
A viral peptide that targets mitochondria protects against neuronal degeneration in models of Parkinson's disease Marion Szelechowski,Alexandre Betourne,Yann Monnet,Cecile A. Ferre,Anne Thouardet al. Nature Communications, 2014, 5, pp.5181. ⟨10.1038/ncomms6181⟩ Article dans une revue hal-01542865v1
MFGE8 does not orchestrate clearance of apoptotic neurons in a mouse model of Parkinson's disease Kiyoka Kinugawa,Yann Monnet,Lixia Lu,Amaury J. Bekaert,Clotilde Theryet al. Neurobiology of Disease, 2013, 51 (SI), pp.192-201. ⟨10.1016/j.nbd.2012.11.010⟩ Article dans une revue istex hal-01545795v1
Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease Carmen Noelker,Lydie Morel,Thomas Lescot,Anke Osterloh,Daniel Alvarez-Fischeret al. Scientific Reports, 2013, 3 (1), pp.1393. ⟨10.1038/srep01393⟩ Article dans une revue hal-01610346v1
DAP12 and CD11b contribute to the microglial-induced death of dopaminergic neurons in vitro but not in vivo in the MPTP mouse model of Parkinson's disease. Kiyoka Kinugawa,Yann Monnet,Catherine Béchade,Daniel Alvarez-Fischer,Etienne Hirschet al. Journal of Neuroinflammation, 2013, 10 (1), pp.82. ⟨10.1186/1742-2094-10-82⟩ Article dans une revue inserm-00847524v1
Neurochemokines: a menage a trois providing new insights on the functions of chemokines in the central nervous system William Rostène,Marc-André Dansereau,David Godefroy,Juliette van Steenwinckel,Annabelle Reaux-Le Goazigoet al. Journal of Neurochemistry, 2011, 118 (5), pp.680-694 Article dans une revue hal-01944671v1
Biological roles of trace elements in the brain with special focus on Zn and Fe S. Bohic,J.-F. Ghersi-Egea,Julien Gibon,P. Paoletti,Josiane Arnaudet al. Revue Neurologique, 2011, 167 (4), pp.269-79. ⟨10.1016/j.neurol.2010.07.035⟩ Article dans une revue hal-01060745v1
Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease. Carine Karachi,David Grabli,Frédéric A. Bernard,Dominique Tandé,Nicolas Wattiezet al. Journal of Clinical Investigation, 2010, 120 (8), pp.2745-54. ⟨10.1172/JCI42642⟩ Article dans une revue inserm-00519393v1
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. Vanessa Brochard,Béhazine Combadière,Annick Prigent,Yasmina Laouar,Aline Perrinet al. Journal of Clinical Investigation, 2009, 119 (1), pp.182-92. ⟨10.1172/JCI36470⟩ Article dans une revue inserm-00393947v1
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease Vanessa Brochard,Béhazine Combadière,Annick Prigent,Yasmina Laouar,Aline Perrinet al. Journal of Clinical Investigation, 2008, ⟨10.1172/JCI36470⟩ Article dans une revue hal-04709683v1

Pré-publication, Document de travail (1)

Parkinson’s disease-derived α-Synuclein assemblies combined with chronic-type inflammatory cues promote a neurotoxic microglial phenotype Cansu Yildirim,Alexis Fenyi,Pierre Besnault,Lina Gomez,Julia E Sepulveda-Diazet al. 2023 Pré-publication, Document de travail hal-04339026v1