Access content directly

Stéphane Bach

90
Documents

Presentation

Publications

Image document

Practical approach to N-benzyl derivatives of 2-amino-8-methoxy-4H-chromene-3-carbonitrile by reductive amination: Exploration of their effects against protein kinases and in silico ADME profiling

Marwa Dhiabi , Ali Bouattour , Mehdi Fakhfakh , Souhir Abid , Ludovic Paquin
Journal of Molecular Structure, 2023, 1274 (Part 1), pp.134319. ⟨10.1016/j.molstruc.2022.134319⟩
Journal articles hal-03867314v1
Image document

Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3α (GSK-3α): Development and impact on temozolomide treatment of glioblastoma cells

Mohamed Hasyeoui , Frédéric Lassagne , William Erb , Manal Nael , Khaled Elokely
Bioorganic Chemistry, 2023, 134, pp.106456. ⟨10.1016/j.bioorg.2023.106456⟩
Journal articles hal-04059446v1

Identification of Novel Compounds Inhibiting the Kinase Activity of the CDK5/p25 Complex via Direct Binding to p25

Riheb Jabeur , Caroline Corbel , Pascal Loyer , Annabelle Le Parc , Adelaide Le Grand
Biochemistry, 2023, 62 (9), pp.1452-1463. ⟨10.1021/acs.biochem.2c00691⟩
Journal articles hal-04089029v1
Image document

From benzofuro-, benzothieno- and 10-methylindolo-[2,3-b]-fused benzothiopyrano[4,3,2-de]quinolines to the corresponding benzothiopyrano[4,3,2-de]1,8-naphthyridines: synthesis and properties of these hexacyclic heteroaromatic compounds

Nicolas Mast , William Erb , Lionel Nauton , Pascale Moreau , Olivier Mongin
New Journal of Chemistry, 2023, 47 (1), pp.258-283. ⟨10.1039/D2NJ04567B⟩
Journal articles hal-03904365v1
Image document

The Roscoff Biological Station in the era of cellular and molecular biology: Focus on the 50 last years of research on marine animals

Patrick Cormier , Agnès Boutet , Pierre Colas , Sandrine Ruchaud , Stéphane Bach
Cahiers de Biologie Marine, 2023, 64 (1), pp.35-52. ⟨10.21411/CBM.A.C705BF49⟩
Journal articles hal-04254376v1
Image document

Quinazoline-based VEGFR-2 inhibitors as potential anti-angiogenic agents: A contemporary perspective of SAR and molecular docking studies

Mahfam Moradi , Alireza Mousavi , Zahra Emamgholipour , Johanna Giovannini , Setareh Moghimi
European Journal of Medicinal Chemistry, 2023, 259, pp.115626. ⟨10.1016/j.ejmech.2023.115626⟩
Journal articles hal-04165313v1
Image document

Overexpression of Eimeria tenella Rhoptry Kinase 2 Induces Early Production of Schizonts

Adeline Ribeiro E Silva , Mamadou Amadou Diallo , Alix Sausset , Thomas Robert , Stéphane Bach
Microbiology Spectrum, 2023, 11 (4), pp.e0013723. ⟨10.1128/spectrum.00137-23⟩
Journal articles hal-04168152v1
Image document

Nigratine as dual inhibitor of necroptosis and ferroptosis regulated cell death

Claire Delehouzé , Arnaud Comte , Stephen Leon-Icaza , Céline Cougoule , Marcelle Hauteville
Scientific Reports, 2022, 12, pp.5118. ⟨10.1038/s41598-022-09019-w⟩
Journal articles hal-03624406v1
Image document

Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases

Dabbugoddu Brahmaiah , Anagani Kanaka Durga Bhavani , Pasula Aparna , Nangunoori Sampath Kumar , Hélène Solhi
Molecules, 2022, 27 (19), pp.6149. ⟨10.3390/molecules27196149⟩
Journal articles hal-03828358v1
Image document

An Optimized Workflow for the Discovery of New Antimicrobial Compounds Targeting Bacterial RNA Polymerase Complex Formation

Alessia Caputo , Sara Sartini , Elisabetta Levati , Ilaria Minato , Gian Marco Elisi
Antibiotics, 2022, 11 (10), pp.1449. ⟨10.3390/antibiotics11101449⟩
Journal articles hal-03857451v1
Image document

Thiazolo[5,4- f ]quinoxalines, Oxazolo[5,4- f ]quinoxalines and Pyrazino[ b,e ]isatins: Synthesis from 6-Aminoquinoxalines and Properties

Frédéric Lassagne , Joshua M. Sims , William Erb , Olivier Mongin , Nicolas Richy
European Journal of Organic Chemistry, 2021, 2021 (19), pp.2756-2763. ⟨10.1002/ejoc.202100362⟩
Journal articles hal-03269555v1
Image document

New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation

Bruno Oyallon , Marie Brachet-Botineau , Cédric Logé , Thomas Robert , Stéphane Bach
Molecules, 2021, 26 (4), pp.867. ⟨10.3390/molecules26040867⟩
Journal articles inserm-03272339v1
Image document

Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases

Viet Hung Dao , Isabelle Ourliac-Garnier , Cédric Logé , Florence Mccarthy , Stéphane Bach
Molecules, 2021, 26 (21), pp.6572. ⟨10.3390/molecules26216572⟩
Journal articles hal-03428747v1
Image document

The Franco-Brazilian network on natural products (FB2NP): a new network promoting cooperation and exchanges in natural products research

Jackson Almeida , Raphaël Grougnet , Lucindo Quintans , Sylvie Chevalier , Marc Feuilloley
Journal articles hal-03592226v1
Image document

From Synthetic Simplified Marine Metabolite Analogues to New Selective Allosteric Inhibitor of Aurora B Kinase

Charlotte Juillet , Ludmila Ermolenko , Dina Boyarskaya , Blandine Baratte , Beátrice Josselin
Journal of Medicinal Chemistry, 2021, 64 (2), pp.1197-1219. ⟨10.1021/acs.jmedchem.0c02064⟩
Journal articles hal-03154739v1
Image document

Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase

Dabbugoddu Brahmaiah , Anagani Kanaka Durga Bhavani , Pasula Aparna , Nangunoori Sampath Kumar , Hélène Solhi
Bioorganic and Medicinal Chemistry, 2021, 31, pp.115962. ⟨10.1016/j.bmc.2020.115962⟩
Journal articles hal-03128547v1
Image document

In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition

Marc-Antoine Bazin , Sandrine Cojean , Fabrice Pagniez , Guillaume Bernadat , Christian Cavé
European Journal of Medicinal Chemistry, 2021, 210, pp.112956. ⟨10.1016/j.ejmech.2020.112956⟩
Journal articles pasteur-03108849v1

Discovery of thiazolidin-4-one analogue as selective GSK-3β inhibitor through structure based virtual screening

Bhanwar Singh Choudhary , Pakhuri Mehta , Stéphane Bach , Sandrine Ruchaud , Thomas Robert
Bioorganic and Medicinal Chemistry Letters, 2021, 52, ⟨10.1016/j.bmcl.2021.128375⟩
Journal articles hal-03867355v1
Image document

Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor

Augustine A. Ahmadu , Claire Delehouze , Anas Haruna , Lukman Mustapha , Bilqis A. Lawal
Molecules, 2021, 26 (15), pp.4599. ⟨10.3390/molecules26154599⟩
Journal articles hal-03331756v1
Image document

Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1

Mohamed Benchekroun , Ludmila Ermolenko , Minh Quan Tran , Agathe Vagneux , Hristo Nedev
European Journal of Medicinal Chemistry, 2020, 201, pp.112337. ⟨10.1016/j.ejmech.2020.112337⟩
Journal articles hal-03004425v2

The Canadian Prairie Plant Thermopsis rhombifolia Contains Luteolin, a Flavone that Inhibits Cyclin Dependent Kinase 9 and Arrest Cells in the G1-Phase of the Cell Cycle

Jan Tuescher , Deserae Tailfeathers , Sophie Kernéis , Blandine Baratte , Sandrine Ruchaud
Journal of Natural Health Product Research, 2020, 2 (2), pp.1-14. ⟨10.33211/jnhpr.12⟩
Journal articles hal-03868334v1

Synthesis and evaluation of C3 substituted chalcone‐based derivatives of 7‐azaindole as protein kinase inhibitors

Malikotsi Qhobosheane , Lesetja Legoabe , Béatrice Josselin , Stéphane Bach , Sandrine Ruchaud
Chemical Biology and Drug Design, inPress, ⟨10.1111/cbdd.13748⟩
Journal articles hal-02906292v1
Image document

Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors

Thomas Robert , Jared L Johnson , Roxane Guichaoua , Tomer M Yaron , Stéphane Bach
Frontiers in Chemistry, 2020, 8, pp.147. ⟨10.3389/fchem.2020.00147⟩
Journal articles hal-02571991v1

Synthesis and kinase inhibitory potencies of new pyrido[3,4-g]quinazolines substituted at the 8-position

Yannick Esvan , Béatrice Josselin , Blandine Baratte , Stéphane Bach , Sandrine Ruchaud
ARKIVOC - Online Journal of Organic Chemistry, 2020, 2020 (7), pp.105-116. ⟨10.24820/ark.5550190.p011.268⟩
Journal articles hal-02926291v1
Image document

Regorafenib analogues and their ferrocenic counterparts: synthesis and biological evaluation

Myron Wilde , Danielle Arzur , Blandine Baratte , Dorian Lefebvre , Thomas Robert
New Journal of Chemistry, 2020, 44 (45), pp.19723-19733. ⟨10.1039/d0nj05334a⟩
Journal articles hal-03100285v1
Image document

Design of new disubstituted imidazo[1,2- b ]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation

Jonathan Elie , Omid Feizbakhsh , Nathalie Desban , Béatrice Josselin , Blandine Baratte
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35 (1), pp.1840-1853. ⟨10.1080/14756366.2020.1825408⟩
Journal articles hal-03004407v1
Image document

Functionalization of 9-thioxanthone at the 1-position: From arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest

Nahida Mokhtari Brikci-Nigassa , Lionel Nauton , Pascale Moreau , Olivier Mongin , Raphael E Duval
Bioorganic Chemistry, 2020, 94, pp.103347. ⟨10.1016/j.bioorg.2019.103347⟩
Journal articles hal-02404054v1
Image document

From simple quinoxalines to potent oxazolo[5,4-f]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3)

Frédéric Lassagne , Camille Duguépéroux , Carlos Roca , Concepción Pérez , Ana Martínez
Organic & Biomolecular Chemistry, 2020, 18 (1), pp.154-162. ⟨10.1039/C9OB02002K⟩
Journal articles hal-02396922v1
Image document

Synthesis of New 2-Phenylamino-4H-chromene-3-carbonitrile Derivatives and Their Effects on Tumor Cell Lines and against Protein Kinases

Ali Bouattour , Mehdi Fakhfakh , Souhir Abid , Ludovic Paquin , Rémy Le Guével
International Journal of Organic Chemistry, 2020, 10, pp.88 - 103. ⟨10.4236/ijoc.2020.102006⟩
Journal articles hal-03869130v2
Image document

La levure modèle et outil… aussi pour la recherche thérapeutique

Stéphane Bach , Pierre Colas , Marc Blondel
Médecine/Sciences, 2020, 36 (5), pp.504-514. ⟨10.1051/medsci/2020077⟩
Journal articles hal-02903981v1

Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors

Malikotsi A Qhobosheane , Lesetja J Legoabe , Béatrice Josselin , Stéphane Bach , Sandrine Ruchaud
Bioorganic and Medicinal Chemistry Letters, 2020, 28 (11), pp.115468. ⟨10.1016/j.bmc.2020.115468⟩
Journal articles hal-03869358v1
Image document

Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency

Nada Ibrahim , Pascal Bonnet , Jean-Daniel Brion , Jean-François Peyrat , Jerome Bignon
European Journal of Medicinal Chemistry, 2020, 199 (31), pp.112355. ⟨10.1016/j.ejmech.2020.112355⟩
Journal articles hal-03036489v1

Synthesis and biological evaluation of selected 7-azaindole derivatives as CDK9/Cyclin T and Haspin inhibitors

Lianie Pieterse , Lesetja J Legoabe , Richard M Beteck , Béatrice Josselin , Stéphane Bach
Medicinal Chemistry Research, 2020, 29, pp.1449 - 1462. ⟨10.1007/s00044-020-02560-1⟩
Journal articles hal-03868372v1
Image document

Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta Phacelocarpus neurymenioides

Sofia-Eléna Motuhi , Omid Feizbakhsh , Beatrice Foll-Josselin , Blandine Baratte , Claire Delehouze
Marine drugs, 2019, Cell Stress, Canonical and Non-Canonical Cell Death Modalities by Marine Natural Compounds and Derivatives, 17 (2), pp.93. ⟨10.3390/md17020093⟩
Journal articles hal-02088007v1
Image document

The Anti-Candida albicans Agent 4-AN Inhibits Multiple Protein Kinases

Maciej Masłyk , Monika Janeczko , Aleksandra Martyna , Sławomir Czernik , Małgorzata Tokarska-Rodak
Molecules, 2019, 24 (1), pp.153. ⟨10.3390/molecules24010153⟩
Journal articles hal-02046526v1
Image document

Kinase inhibitions in pyrido[4,3-h] and [3,4-g]quinazolines: Synthesis, SAR and molecular modeling studies

Waël Zeinyeh , Yannick Esvan , Béatrice Josselin , Blandine Baratte , Stéphane Bach
Bioorganic and Medicinal Chemistry, 2019, 27 (10), pp.2083-2089. ⟨10.1016/j.bmc.2019.04.005⟩
Journal articles hal-02164744v1
Image document

Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge Crambe tailliezi

Thi-Ngoc-Dung Nguyen , Omid Feizbakhsh , Estelle Sfecci , Blandine Baratte , Claire Delehouzé
Marine drugs, 2019, 17 (10), pp.569. ⟨10.3390/md17100569⟩
Journal articles hal-03864501v1
Image document

New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis

Helmi Tazarki , Wael Zeinyeh , Yannick J. Esvan , Stefan Knapp , Deep Chatterjee
European Journal of Medicinal Chemistry, 2019, 166, pp.304-317. ⟨10.1016/j.ejmech.2019.01.052⟩
Journal articles hal-02150788v1
Image document

Biological Evaluation of Arylsemicarbazone Derivatives as Potential Anticancer Agents

Anne Cecília Nascimento da Cruz , Dalci José Brondani , Temístocles Ítalo de Santana , Lucas Oliveira da Silva , Elizabeth Fernanda da Oliveira Borba
Pharmaceuticals, 2019, 12 (4), pp.169. ⟨10.3390/ph12040169⟩
Journal articles hal-03864455v1
Image document

New Antimicrobials Targeting Bacterial RNA Polymerase Holoenzyme Assembly Identified with an in Vivo BRET-Based Discovery Platform

Sara Sartini , Elisabetta Levati , Martina Maccesi , Matteo Guerra , Gilberto Spadoni
ACS Chemical Biology, 2019, 14 (8), pp.1727 - 1736. ⟨10.1021/acschembio.9b00178⟩
Journal articles hal-03870173v1
Image document

Synthesis and evaluation of new isatin-aminorhodanine hybrids as PIM1 and CLK1 kinase inhibitors

Khadidja Khaldoun , Abdelmounaim Safer , Nourdine Boukabcha , Necmi Dege , Sandrine Ruchaud
Journal of Molecular Structure, 2019, 1192, pp.82 - 90. ⟨10.1016/j.molstruc.2019.04.122⟩
Journal articles hal-03870645v1
Image document

Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3

Killian Oukoloff , Nicolas Coquelle , Manuela Bartolini , Marina Naldi , Rémy Le Guével
European Journal of Medicinal Chemistry, 2019, 168, pp.58-77. ⟨10.1016/j.ejmech.2018.12.063⟩
Journal articles hal-02055769v1
Image document

From Quinoxaline, Pyrido[2,3-b]pyrazine and Pyrido[3,4-b]pyrazine to Pyrazino-Fused Carbazoles and Carbolines

Frédéric Lassagne , Timothy Langlais , Elsa Caytan , Emmanuelle Limanton , Ludovic Paquin
Molecules, 2018, 23 (11), pp.2961. ⟨10.3390/molecules23112961⟩
Journal articles hal-03867783v1
Image document

Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors

Bruno Oyallon , Marie Brachet-Botineau , Cédric Logé , Pascal Bonnet , Mohamed Souab
European Journal of Medicinal Chemistry, 2018, 154, pp.101-109. ⟨10.1016/j.ejmech.2018.04.056⟩
Journal articles hal-03408667v1

Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition

Hannah Winfield , Michael Cahill , Kevin O'Shea , Larry Pierce , Thomas Robert
Bioorganic and Medicinal Chemistry, 2018, 26 (14), pp.4209-4224. ⟨10.1016/j.bmc.2018.07.012⟩
Journal articles hal-03011414v1

Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration

Viet Hung Dao , Isabelle Ourliac-Garnier , Marc-Antoine Bazin , Catherine Jacquot , Blandine Baratte
Bioorganic and Medicinal Chemistry, 2018, 28 (13), pp.2250-2255. ⟨10.1016/j.bmcl.2018.05.044⟩
Journal articles hal-03011408v1
Image document

Phenytoin inhibits necroptosis

Anne von Mässenhausen , Wulf Tonnus , Nina Himmerkus , Simon Parmentier , Danish Saleh
Cell Death and Disease, 2018, 9 (3), pp.359. ⟨10.1038/s41419-018-0394-3⟩
Journal articles hal-03871390v1
Image document

A combined experimental and theoretical study of the thermal [3+2] cycloaddition of carbonyl ylides with activated alkenes

Samira Hamza-Reguig , Ghenia Bentabed-Ababsa , Luis R Domingo , Mar Ríos-Gutiérrez , Stephanie Philippot
Journal of Molecular Structure, 2018, 1157, pp.276-287. ⟨10.1016/j.molstruc.2017.12.052⟩
Journal articles hal-01695551v2
Image document

2-Aminophenones, a common precursor to N-aryl isatins and acridines endowed with bioactivities

Nahida Mokhtari Brikci-Nigassa , Ghenia Bentabed-Ababsa , William Erb , Floris Chevallier , Laurent Picot
Tetrahedron, 2018, 74 (15), pp.1785-1801. ⟨10.1016/j.tet.2018.02.038⟩
Journal articles hal-01774406v1

Effect of cell cycle arrest on intermediate metabolism in the marine diatom Phaeodactylum tricornutum

Joomi Kim , Christopher M Brown , Min Kyung Kim , Elizabeth H Burrows , Stéphane Bach
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (38), ⟨10.1073/pnas.1711642114⟩
Journal articles hal-03875262v1
Image document

Li 2.0 Ni 0.67 N: a promising negative electrode material for Li-ion batteries with a soft structural response

Thomas Cavoué , Nicolas Emery , Nurzhan Umirov , Stéphane Bach , Pascal Berger
Inorganic Chemistry, 2017, 56, pp.13815-13821. ⟨10.1021/acs.inorgchem.7b01903⟩
Journal articles cea-01626781v1
Image document

Bioactive Metabolites from the Deep Subseafloor Fungus Oidiodendron griseum UBOCC-A-114129

Marion Navarri , C. Jégou , Arnaud Bondon , Sandrine Pottier , Stéphane Bach
Marine drugs, 2017, 15 (4), ⟨10.3390/md15040111⟩
Journal articles hal-01518044v1
Image document

Synthesis, docking study and kinase inhibitory activity of a number of new substituted pyrazolo[3,4-c]pyridines

Meropi Sklepari , Nikolaos Lougiakis , Athanasios Papastathopoulos , Nicole Pouli , Panagiotis Marakos
Chemical and Pharmaceutical Bulletin, 2017, ⟨10.1248/cpb.c16-00704⟩
Journal articles hal-03875290v1
Image document

Fused Systems Based on 2-Aminopyrimidines: Synthesis Combining Deprotolithiation-in situ Zincation with N -Arylation Reactions and Biological Properties

Madani Hedidi , Julien Maillard , William Erb , Frédéric Lassagne , Yury S Halauko
European Journal of Organic Chemistry, 2017, 2017 (39), pp.5903-5915. ⟨10.1002/ejoc.201701004⟩
Journal articles hal-01624382v1

Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells

Madani Hedidi , Julien Maillard , William Erb , Frédéric Lassagne , Yury Halauko
Tetrahedron, 2016, 72 (39), pp.6467 - 6476. ⟨10.1016/j.tet.2016.08.056⟩
Journal articles hal-03875302v1

Microwave synthesis of new 3-(3-aminopropyl)-5-arylidene-2-thioxo-1,3-thiazolidine-4-ones as potential Ser/Thr protein kinase inhibitors

Camille Déliko Dago , Wacothon Karime Coulibaly , Yves-Alain Bekro , Janat A. Mamyrbekova-Bekro , Beatrice Foll-Josselin
Medicinal Chemistry Research, 2016, 25 (12), pp.2940--2958. ⟨10.1007/s00044-016-1719-3⟩
Journal articles hal-01414293v1
Image document

Marine Natural Products from New Caledonia—A Review

Sofia-Eléna Motuhi , Mohamed Mehiri , Claude Payri , Stéphane La Barre , Stéphane Bach
Marine drugs, 2016, 14 (3), pp.58. ⟨10.3390/md14030058⟩
Journal articles hal-01292225v1
Image document

Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases

Camille Déliko Dago , Christelle Ambeu , Wacothon-Karime Coulibaly , Yves-Alain Békro , Janat Mamyrbékova
Molecules, 2015, 20 (7), pp.12412-12435. ⟨10.3390/molecules200712412⟩
Journal articles hal-01187427v1

Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1

Espérance Moine , Isabelle Dimier-Poisson , Cécile Enguehard-Gueiffier , Cédric Logé , Mélanie Pénichon
European Journal of Medicinal Chemistry, 2015, 105, pp.80-105. ⟨10.1016/j.ejmech.2015.10.004⟩
Journal articles hal-02389861v1

Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines

Pascal Marchand , Marc-Antoine Bazin , Fabrice Pagniez , Guillaume Rivière , Lizeth Bodero
European Journal of Medicinal Chemistry, 2015, 103, pp.381-395. ⟨10.1016/j.ejmech.2015.09.002⟩
Journal articles hal-03216056v1

Tamoxifen Inhibits CDK5 Kinase Activity by Interacting with p35/p25 and Modulates the Pattern of Tau Phosphorylation.

Caroline Corbel , Bing Zhang , Annabelle Le Parc , Blandine Baratte , Pierre Colas
Chemistry & biology, 2015, 22 (4), pp.472-482
Journal articles hal-01145976v1
Image document

Azine and Diazine Functionalization Using 2,2,6,6-Tetramethylpiperidino-Based Lithium–Metal Combinations: Application to the Synthesis of 5,9-Disubstituted Pyrido[3′,2′:4,5]pyrrolo[1,2-c] pyrimidines

Nada Marquise , Tan Tai Nguyen , Floris Chevallier , Laurent Picot , Valérie Thiéry
SYNLETT, 2015, 26 (20), pp.2811-2816. ⟨10.1055/s-0035-1560496⟩
Journal articles hal-01248092v1

A Comparative Insight of Potassium Vanadates as Positive Electrode Materials for Li Batteries: Influence of the Long-Range and Local Structure

Rita Baddour-Hadjean , Arezki Boudaoud , Stéphane Bach , Nicolas Emery , Jean Pierre Pereira-Ramos
Inorganic Chemistry, 2014, 53 (3), pp.1764-1772. ⟨10.1021/ic402897d⟩
Journal articles hal-03131789v1
Image document

Bioprospecting Marine Plankton

Heni Abida , Sandrine Ruchaud , Laurent Rios , Anne Humeau , Ian Probert
Marine drugs, 2013, 11 (11), pp.4594-4611. ⟨10.3390/md11114594⟩
Journal articles hal-01258229v1

First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors.

Caroline Corbel , Qian Wang , Hadjira Bousserouel , Amel Hamdi , Bing Zhang
Biotechnology Journal, 2011, 6 (7), pp.860-70. ⟨10.1002/biot.201100138⟩
Journal articles hal-00628746v1

An in silico approach for the discovery of CDK5/p25 interaction inhibitors.

Bing Zhang , Caroline Corbel , Françoise Guéritte , Cyril Couturier , Stéphane Bach
Biotechnology Journal, 2011, 6 (7), pp.871-881. ⟨10.1002/biot.201100139⟩
Journal articles hal-00628754v1

Identification of potential cellular targets of aloisine A by affinity chromatography.

Caroline Corbel , Rose Haddoub , Damien Guiffant , Olivier Lozach , David Gueyrard
Bioorganic and Medicinal Chemistry, 2009, 17 (15), pp.5572-82. ⟨10.1016/j.bmc.2009.06.024⟩
Journal articles hal-00416033v1
Image document

Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions.

Déborah Tribouillard-Tanvier , Vincent Béringue , Nathalie Desban , Fabienne Gug , Stéphane Bach
PLoS ONE, 2008, 3 (4), pp.e1981. ⟨10.1371/journal.pone.0001981⟩
Journal articles hal-00416056v1
Image document

Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs

Déborah Tribouillard-Tanvier , Suzana dos Reis , Fabienne Gug , Cécile Voisset , Vincent Béringue
PLoS ONE, 2008, 3 (5), pp.e2174. ⟨10.1371/journal.pone.0002174⟩
Journal articles hal-02134950v1

Identification of intracellular targets of small molecular weight chemical compounds using affinity chromatography.

Damien Guiffant , Déborah Tribouillard , Fabienne Gug , Hervé Galons , Laurent Meijer
Biotechnology Journal, 2007, 2 (1), pp.68-75. ⟨10.1002/biot.200600223⟩
Journal articles hal-00169462v1

Improved tumor control through circadian clock induction by Seliciclib, a cyclin-dependent kinase inhibitor.

Ida Iurisci , Elisabeth Filipski , Jens Reinhardt , Stéphane Bach , Athos Gianella-Borradori
Cancer Research, 2006, 66 (22), pp.10720-8. ⟨10.1158/0008-5472.CAN-06-2086⟩
Journal articles hal-00169367v1
Image document

A yeast-based assay to isolate drugs active against mammalian prions

Stéphane Bach , Déborah Tribouillard , Nicolas Talarek , Nathalie Desban , Marc Blondel
Methods, 2006, 39 (1), pp.72-77. ⟨10.1016/j.ymeth.2006.04.005⟩
Journal articles hal-02134947v1

Using budding yeast to screen for anti-prion drugs

Déborah Tribouillard , Stéphane Bach , Fabienne Gug , Nathalie Desban , Vincent Béringue
Biotechnology Journal, 2006, 1 (1), pp.58-67. ⟨10.1002/biot.200500001⟩
Journal articles hal-02660470v1
Image document

Roscovitine Targets, Protein Kinases and Pyridoxal Kinase

Stéphane Bach , Marie Knockaert , Jens Reinhardt , Olivier Lozach , Sophie Schmitt
Journal of Biological Chemistry, 2005, 280, pp.31208 - 31219. ⟨10.1074/jbc.m500806200⟩
Journal articles hal-03867064v1

Raman investigation of the structural changes in anatase LixTiO2 upon electrochemical lithium insertion

Rita Baddour-Hadjean , Stéphane Bach , Mikhail Smirnov , Jean Pierre Pereira-Ramos
Journal of Raman Spectroscopy, 2004, 35 (7), pp.577-585. ⟨10.1002/jrs.1200⟩
Journal articles hal-03131945v1
Image document

Isolation of drugs active against mammalian prions using a yeast-based screening assay

Stéphane Bach , Nicolas Talarek , Thibault Andrieu , Jean-Michel Vierfond , Yvette Mettey
Nature Biotechnology, 2003, 21 (9), pp.1075-1081. ⟨10.1038/nbt855⟩
Journal articles hal-02127591v1

Eimeria tenella ROP kinase 2 induces p38 MAPK cellular pathway

Adeline Ribeiro E Silva , Mamadou Diallo , Alix Sausset , Thomas Robert , Stéphane Bach
Journées d’Animation Scientifique du Département Santé Animale (JAS SA), Oct 2022, Anglet, France.
Conference poster hal-03852796v1

Eimeria tenella induces p38 MAPK signalling pathway

Adeline Ribeiro E Silva , Mamadou Diallo , Alix Sausset , Thomas Robert , Stéphane Bach
Journées d'Animation Scientifique de la FéRI 2022- FéRI Scientific Days 2022, Région Centre Val de Loire, Jul 2022, Tours, France
Conference poster hal-03735655v1

Conception, synthèse et évaluation de nouveaux inhibiteurs de TgCDPK1 à visée anti-toxoplasmique

Espérance Moine , Isabelle Dimier-Poisson , Cécile Enguehard-Gueiffier , Mélanie Pouvreau , Nathalie Moiré
Days of the Research Federation in Infectious Diseases, Oct 2015, Orléans, France. 2015
Conference poster hal-02793392v1