Stéphane Bach

Publications

Article dans une revue (92)

Qualitative Trends versus Quantitative Accuracy: A Case Study of LiMn&lt;sub&gt;1.5&lt;/sub&gt;Ni&lt;sub&gt;0.5&lt;/sub&gt;O&lt;sub&gt;4&lt;/sub&gt; Cathode Material Adama Gassama,Etienne Mangaud,Alexander Mitrushchenkov,Céline Léonard,E. Suardet al. Journal of Materials Chemistry A, In press, ⟨10.1039/D6TA00540C⟩ Article dans une revue hal-05555390v1
Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2- a ]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy Lhana Tisseur,Cédric Logé,Sandrine Cojean,Khadidiatou Gassama,Lilian Karcheret al. RSC Medicinal Chemistry, 2025, 16, pp.3746-3763. ⟨10.1039/d5md00257e⟩ Article dans une revue hal-05173262v1
Research towards selective inhibition of the CLK3 kinase Vinay Kumar Singh,Frédéric Justaud,Dabbugoddu Brahmaiah,Nangunoori Sampath Kumar,Blandine Baratteet al. Beilstein Journal of Organic Chemistry, 2025, 21, pp.2250-2259. ⟨10.3762/bjoc.21.172⟩ Article dans une revue hal-05380390v1
New Insights into the Anticancer Effects and Toxicogenomic Safety of Two β-Lapachone Derivatives José Rivaldo de Lima,Alexandre José da Silva Góes,Elizabeth Fernanda de Oliveira Borba,Meykson Alexandre da Silva,Rodrigo Ribeiro Alves Caianaet al. Pharmaceuticals, 2025, 18 (6), ⟨10.3390/ph18060837⟩ Article dans une revue hal-05336919v1
BF2 Complexes of N-arylated 1-amino-anthraquinone, -xanthone, -thioxanthone, and Related Compounds: Synthesis and Properties Ahlem N. Khelf‐maghraoui,Ghenia Bentabed-Ababsa,Nicolas Mast,William Erb,Jean-Pierre Hurvoiset al. European Journal of Organic Chemistry, 2025, pp.e202500470. ⟨10.1002/ejoc.202500470⟩ Article dans une revue hal-05408484v1
Sibiriline, a novel dual inhibitor of necroptosis and ferroptosis, prevents RIPK1 kinase activity and (phospho)lipid peroxidation as a potential therapeutic strategy Claire Delehouze,Melodie Mallais,Arnaud Comte,Romain Lucas,Blandine Baratteet al. Cell Death Discovery, 2025, 11 (1), pp.552. ⟨10.1038/s41420-025-02852-8⟩ Article dans une revue hal-05405086v1
On the Synthesis of [1,3]Azaphospholo[4,5‐f]quino(xa)lines and 2,3‐Dihydro‐[1,3]azaphospholo[4,5‐f]quino(xa)line 1‐oxides Mohamed Ali Dridi,Mohamed Hasyeoui,Frédéric Lassagne,William Erb,Charline Piroudet al. European Journal of Organic Chemistry, 2025, pp.e202500080. ⟨10.1002/ejoc.202500080⟩ Article dans une revue hal-04975365v1
Investigating the C2 Modulation of the Imidazo[1,2‐ a ]pyrazine‐Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition Lhana Tisseur,Sandrine Cojean,Khadidiatou Gassama,Cédric Logé,Fabrice Pagniezet al. ChemMedChem, 2025, 20 (6), pp.e202400862. ⟨10.1002/cmdc.202400862⟩ Article dans une revue hal-05181232v1
Ethaverine and Papaverine Target Cyclin-Dependent Kinase 5 and Inhibit Lung Cancer Cell Proliferation and Migration Arthur Laure,Chloe Royet,Frédéric Bihel,Blandine Baratte,Stéphane Bachet al. ACS Pharmacology & Translational Science, 2024, 7 (5), pp.1377-1385. ⟨10.1021/acsptsci.4c00023⟩ Article dans une revue hal-04609131v1
XPS Investigation of Co–Ni Oxidized Compounds Surface Using Peak-On-Satellite Ratio. Application to Co 20 Ni 80 Passive Layer Structure and Composition Barbara Laïk,Morgane Richet,Nicolas Emery,Stephane Bach,Loïc Perrièreet al. ACS Omega, 2024, 9 (39), pp.40707-40722. ⟨10.1021/acsomega.4c05082⟩ Article dans une revue hal-04729466v1
Novel Thiazole-Fused [4,5-g] or [5,4-g]Quinazolin-8-ones and Their Quinazoline Analogues: Synthesis and Biological Evaluation Nathan Broudic,Alexandra Pacheco-Benichou,Cecile Corbiere,Blandine Baratte,Thomas Robertet al. Pharmaceuticals, 2024, 17 (11), pp.1452. ⟨10.3390/ph17111452⟩ Article dans une revue hal-04783236v1
New Fusarochromanone Derivatives from the Marine Fungus Fusarium equiseti UBOCC-A-117302 Giang Nam Pham,Béatrice Josselin,Arnaud Cousseau,Blandine Baratte,Marie Dayraset al. Marine drugs, 2024, 22 (10), pp.444. ⟨10.3390/md22100444⟩ Article dans une revue hal-05397856v1
Practical approach to N-benzyl derivatives of 2-amino-8-methoxy-4H-chromene-3-carbonitrile by reductive amination: Exploration of their effects against protein kinases and in silico ADME profiling Marwa Dhiabi,Ali Bouattour,Mehdi Fakhfakh,Souhir Abid,Ludovic Paquinet al. Journal of Molecular Structure, 2023, 1274 (Part 1), pp.134319. ⟨10.1016/j.molstruc.2022.134319⟩ Article dans une revue hal-03867314v1
Potassium 6-Oxo-7,13,16,22-tetraazatetracyclo[12.6.2.18,12.017,21]tricosa-1(20),8(23),9,11,14,16,18,21-octaen-2-yne-15-carboxylate Camille Blouet,Stéphanie Letast,Thomas Robert,Stéphane Bach,Noël Pinaudet al. Molbank, 2023, 2023 (4), pp.M1735. ⟨10.3390/M1735⟩ Article dans une revue hal-04805282v1
Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3α (GSK-3α): Development and impact on temozolomide treatment of glioblastoma cells Mohamed Hasyeoui,Frédéric Lassagne,William Erb,Manal Nael,Khaled Elokelyet al. Bioorganic Chemistry, 2023, 134, pp.106456. ⟨10.1016/j.bioorg.2023.106456⟩ Article dans une revue hal-04059446v1
The Roscoff Biological Station in the era of cellular and molecular biology: Focus on the 50 last years of research on marine animals Patrick Cormier,Agnès Boutet,Pierre Colas,Sandrine Ruchaud,Stéphane Bachet al. Cahiers de Biologie Marine, 2023, 64 (1), pp.35-52. ⟨10.21411/CBM.A.C705BF49⟩ Article dans une revue hal-04254376v1
Control of the nanostructure of MgO–Y2O3 composite ceramics using two-step sintering for high temperature mid infrared window applications Nathan Brard,Johan Petit,Nicolas Emery,Nicolas Horezan,Stéphane Bach Ceramics International, 2023, 49 (11), pp.18187-18194. ⟨10.1016/j.ceramint.2023.02.187⟩ Article dans une revue hal-04023577v1
Identification of Novel Compounds Inhibiting the Kinase Activity of the CDK5/p25 Complex via Direct Binding to p25 Riheb Jabeur,Caroline Corbel,Pascal Loyer,Annabelle Le Parc,Adelaide Le Grandet al. Biochemistry, 2023, 62 (9), pp.1452-1463. ⟨10.1021/acs.biochem.2c00691⟩ Article dans une revue hal-04089029v1
From benzofuro-, benzothieno- and 10-methylindolo-[2,3-b]-fused benzothiopyrano[4,3,2-de]quinolines to the corresponding benzothiopyrano[4,3,2-de]1,8-naphthyridines: synthesis and properties of these hexacyclic heteroaromatic compounds Nicolas Mast,William Erb,Lionel Nauton,Pascale Moreau,Olivier Monginet al. New Journal of Chemistry, 2023, 47 (1), pp.258-283. ⟨10.1039/D2NJ04567B⟩ Article dans une revue hal-03904365v1
Overexpression of Eimeria tenella Rhoptry Kinase 2 Induces Early Production of Schizonts Adeline Ribeiro E Silva,Mamadou Amadou Diallo,Alix Sausset,Thomas Robert,Stéphane Bachet al. Microbiology Spectrum, 2023, 11 (4), pp.e0013723. ⟨10.1128/spectrum.00137-23⟩ Article dans une revue hal-04168152v1
Quinazoline-based VEGFR-2 inhibitors as potential anti-angiogenic agents: A contemporary perspective of SAR and molecular docking studies Mahfam Moradi,Alireza Mousavi,Zahra Emamgholipour,Johanna Giovannini,Setareh Moghimiet al. European Journal of Medicinal Chemistry, 2023, 259, pp.115626. ⟨10.1016/j.ejmech.2023.115626⟩ Article dans une revue hal-04165313v1
Nigratine as dual inhibitor of necroptosis and ferroptosis regulated cell death Claire Delehouzé,Arnaud Comte,Stephen Adonai Leon-Icaza,Céline Cougoule,Marcelle Hautevilleet al. Scientific Reports, 2022, 12 (1), pp.5118. ⟨10.1038/s41598-022-09019-w⟩ Article dans une revue hal-04835337v2
The Franco-Brazilian network on natural products (FB2NP): a new network promoting cooperation and exchanges in natural products research Jackson Almeida,Raphaël Grougnet,Lucindo Quintans,Sylvie Chevalier,Marc Feuilloleyet al. Química Nova, 2022, 45, pp.1-3. ⟨10.21577/0100-4042.20170847⟩ Article dans une revue hal-03592226v1
Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases Dabbugoddu Brahmaiah,Anagani Kanaka Durga Bhavani,Pasula Aparna,Nangunoori Sampath Kumar,Hélène Solhiet al. Molecules, 2022, 27 (19), pp.6149. ⟨10.3390/molecules27196149⟩ Article dans une revue hal-03828358v1
An Optimized Workflow for the Discovery of New Antimicrobial Compounds Targeting Bacterial RNA Polymerase Complex Formation Alessia Caputo,Sara Sartini,Elisabetta Levati,Ilaria Minato,Gian Marco Elisiet al. Antibiotics, 2022, 11 (10), pp.1449. ⟨10.3390/antibiotics11101449⟩ Article dans une revue hal-03857451v1
Thiazolo[5,4- &lt;i&gt;f&lt;/i&gt; ]quinoxalines, Oxazolo[5,4- &lt;i&gt;f&lt;/i&gt; ]quinoxalines and Pyrazino[ &lt;i&gt;b,e&lt;/i&gt; ]isatins: Synthesis from 6-Aminoquinoxalines and Properties Frédéric Lassagne,Joshua M. Sims,William Erb,Olivier Mongin,Nicolas Richyet al. European Journal of Organic Chemistry, 2021, 2021 (19), pp.2756-2763. ⟨10.1002/ejoc.202100362⟩ Article dans une revue hal-03269555v1
Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases Viet Hung Dao,Isabelle Ourliac-Garnier,Cédric Logé,Florence Mccarthy,Stéphane Bachet al. Molecules, 2021, 26 (21), pp.6572. ⟨10.3390/molecules26216572⟩ Article dans une revue hal-03428747v1
Discovery of thiazolidin-4-one analogue as selective GSK-3β inhibitor through structure based virtual screening Bhanwar Singh Choudhary,Pakhuri Mehta,Stéphane Bach,Sandrine Ruchaud,Thomas Robertet al. Bioorganic and Medicinal Chemistry Letters, 2021, 52, ⟨10.1016/j.bmcl.2021.128375⟩ Article dans une revue hal-03867355v1
Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor Augustine A. Ahmadu,Claire Delehouze,Anas Haruna,Lukman Mustapha,Bilqis A. Lawalet al. Molecules, 2021, 26 (15), pp.4599. ⟨10.3390/molecules26154599⟩ Article dans une revue hal-03331756v1
New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation Bruno Oyallon,Marie Brachet-Botineau,Cédric Logé,Thomas Robert,Stéphane Bachet al. Molecules, 2021, 26 (4), pp.867. ⟨10.3390/molecules26040867⟩ Article dans une revue inserm-03272339v1
From Synthetic Simplified Marine Metabolite Analogues to New Selective Allosteric Inhibitor of Aurora B Kinase Charlotte Juillet,Ludmila Ermolenko,Dina Boyarskaya,Blandine Baratte,Beátrice Josselinet al. Journal of Medicinal Chemistry, 2021, 64 (2), pp.1197-1219. ⟨10.1021/acs.jmedchem.0c02064⟩ Article dans une revue hal-03154739v1
In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition Marc-Antoine Bazin,Sandrine Cojean,Fabrice Pagniez,Guillaume Bernadat,Christian Cavéet al. European Journal of Medicinal Chemistry, 2021, 210, pp.112956. ⟨10.1016/j.ejmech.2020.112956⟩ Article dans une revue pasteur-03108849v1
Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase Dabbugoddu Brahmaiah,Anagani Kanaka Durga Bhavani,Pasula Aparna,Nangunoori Sampath Kumar,Hélène Solhiet al. Bioorganic and Medicinal Chemistry, 2021, 31, pp.115962. ⟨10.1016/j.bmc.2020.115962⟩ Article dans une revue hal-03128547v1
Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1 Mohamed Benchekroun,Ludmila Ermolenko,Minh Quan Tran,Agathe Vagneux,Hristo Nedevet al. European Journal of Medicinal Chemistry, 2020, 201, pp.112337. ⟨10.1016/j.ejmech.2020.112337⟩ Article dans une revue hal-03004425v2
The Canadian Prairie Plant Thermopsis rhombifolia Contains Luteolin, a Flavone that Inhibits Cyclin Dependent Kinase 9 and Arrest Cells in the G1-Phase of the Cell Cycle Jan Tuescher,Deserae Tailfeathers,Sophie Kernéis,Blandine Baratte,Sandrine Ruchaudet al. Journal of Natural Health Product Research, 2020, 2 (2), pp.1-14. ⟨10.33211/jnhpr.12⟩ Article dans une revue hal-03868334v1
Synthesis and kinase inhibitory potencies of new pyrido[3,4-g]quinazolines substituted at the 8-position Yannick Esvan,Béatrice Josselin,Blandine Baratte,Stéphane Bach,Sandrine Ruchaudet al. ARKIVOC - Online Journal of Organic Chemistry, 2020, 2020 (7), pp.105-116. ⟨10.24820/ark.5550190.p011.268⟩ Article dans une revue hal-02926291v1
Synthesis and evaluation of C3 substituted chalcone‐based derivatives of 7‐azaindole as protein kinase inhibitors Malikotsi Qhobosheane,Lesetja Legoabe,Béatrice Josselin,Stéphane Bach,Sandrine Ruchaudet al. Chemical Biology and Drug Design, In press, ⟨10.1111/cbdd.13748⟩ Article dans une revue hal-02906292v1
Synthesis and evaluation of 7-azaindole derivatives bearing benzocycloalkanone motifs as protein kinase inhibitors Malikotsi A Qhobosheane,Lesetja J Legoabe,Béatrice Josselin,Stéphane Bach,Sandrine Ruchaudet al. Bioorganic and Medicinal Chemistry Letters, 2020, 28 (11), pp.115468. ⟨10.1016/j.bmc.2020.115468⟩ Article dans une revue hal-03869358v1
Synthesis and biological evaluation of selected 7-azaindole derivatives as CDK9/Cyclin T and Haspin inhibitors Lianie Pieterse,Lesetja J Legoabe,Richard M Beteck,Béatrice Josselin,Stéphane Bachet al. Medicinal Chemistry Research, 2020, 29, pp.1449 - 1462. ⟨10.1007/s00044-020-02560-1⟩ Article dans une revue hal-03868372v1
Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency Nada Ibrahim,Pascal Bonnet,Jean-Daniel Brion,Jean-François Peyrat,Jerome Bignonet al. European Journal of Medicinal Chemistry, 2020, 199 (31), pp.112355. ⟨10.1016/j.ejmech.2020.112355⟩ Article dans une revue hal-03036489v1
La levure modèle et outil… aussi pour la recherche thérapeutique Stéphane Bach,Pierre Colas,Marc Blondel Médecine/Sciences, 2020, 36 (5), pp.504-514. ⟨10.1051/medsci/2020077⟩ Article dans une revue hal-02903981v1
Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors Thomas Robert,Jared L Johnson,Roxane Guichaoua,Tomer M Yaron,Stéphane Bachet al. Frontiers in Chemistry, 2020, 8, pp.147. ⟨10.3389/fchem.2020.00147⟩ Article dans une revue hal-02571991v1
Design of new disubstituted imidazo[1,2- b ]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation Jonathan Elie,Omid Feizbakhsh,Nathalie Desban,Béatrice Josselin,Blandine Baratteet al. Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35 (1), pp.1840-1853. ⟨10.1080/14756366.2020.1825408⟩ Article dans une revue hal-03004407v1
Regorafenib analogues and their ferrocenic counterparts: synthesis and biological evaluation Myron Wilde,Danielle Arzur,Blandine Baratte,Dorian Lefebvre,Thomas Robertet al. New Journal of Chemistry, 2020, 44 (45), pp.19723-19733. ⟨10.1039/d0nj05334a⟩ Article dans une revue hal-03100285v1
Synthesis of New 2-Phenylamino-4H-chromene-3-carbonitrile Derivatives and Their Effects on Tumor Cell Lines and against Protein Kinases Ali Bouattour,Mehdi Fakhfakh,Souhir Abid,Ludovic Paquin,Rémy Le Guévelet al. International Journal of Organic Chemistry, 2020, 10, pp.88 - 103. ⟨10.4236/ijoc.2020.102006⟩ Article dans une revue hal-03869130v2
Functionalization of 9-thioxanthone at the 1-position: From arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest Nahida Mokhtari Brikci-Nigassa,Lionel Nauton,Pascale Moreau,Olivier Mongin,Raphael E Duvalet al. Bioorganic Chemistry, 2020, 94, pp.103347. ⟨10.1016/j.bioorg.2019.103347⟩ Article dans une revue hal-02404054v1
From simple quinoxalines to potent oxazolo[5,4-f]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3) Frédéric Lassagne,Camille Duguépéroux,Carlos Roca,Concepción Pérez,Ana Martínezet al. Organic & Biomolecular Chemistry, 2020, 18 (1), pp.154-162. ⟨10.1039/C9OB02002K⟩ Article dans une revue hal-02396922v1
Bilayered Potassium Vanadate K0.5V2O5 as Superior Cathode Material for Na‐ion Batteries Rita Baddour-Hadjean,Le Than Nguyen Huyhn,Daureen Batyrbekuly,Stephane Bach,Jean Pierre Pereira-Ramos ChemSusChem, 2019, 12 (23), pp.5192-5198. ⟨10.1002/cssc.201902093⟩ Article dans une revue hal-02336034v1
Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta Phacelocarpus neurymenioides Sofia-Eléna Motuhi,Omid Feizbakhsh,Beatrice Foll-Josselin,Blandine Baratte,Claire Delehouzeet al. Marine drugs, 2019, Cell Stress, Canonical and Non-Canonical Cell Death Modalities by Marine Natural Compounds and Derivatives, 17 (2), pp.93. ⟨10.3390/md17020093⟩ Article dans une revue hal-02088007v1
New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis Helmi Tazarki,Wael Zeinyeh,Yannick J. Esvan,Stefan Knapp,Deep Chatterjeeet al. European Journal of Medicinal Chemistry, 2019, 166, pp.304-317. ⟨10.1016/j.ejmech.2019.01.052⟩ Article dans une revue hal-02150788v1
The Anti-Candida albicans Agent 4-AN Inhibits Multiple Protein Kinases Maciej Masłyk,Monika Janeczko,Aleksandra Martyna,Sławomir Czernik,Małgorzata Tokarska-Rodaket al. Molecules, 2019, 24 (1), pp.153. ⟨10.3390/molecules24010153⟩ Article dans une revue hal-02046526v1
Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 Killian Oukoloff,Nicolas Coquelle,Manuela Bartolini,Marina Naldi,Rémy Le Guévelet al. European Journal of Medicinal Chemistry, 2019, 168, pp.58-77. ⟨10.1016/j.ejmech.2018.12.063⟩ Article dans une revue hal-02055769v1
Biological Evaluation of Arylsemicarbazone Derivatives as Potential Anticancer Agents Anne Cecília Nascimento da Cruz,Dalci José Brondani,Temístocles Ítalo de Santana,Lucas Oliveira da Silva,Elizabeth Fernanda da Oliveira Borbaet al. Pharmaceuticals, 2019, 12 (4), pp.169. ⟨10.3390/ph12040169⟩ Article dans une revue hal-03864455v2
Kinase inhibitions in pyrido[4,3-h] and [3,4-g]quinazolines: Synthesis, SAR and molecular modeling studies Waël Zeinyeh,Yannick Esvan,Béatrice Josselin,Blandine Baratte,Stéphane Bachet al. Bioorganic and Medicinal Chemistry, 2019, 27 (10), pp.2083-2089. ⟨10.1016/j.bmc.2019.04.005⟩ Article dans une revue hal-02164744v1
Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge Crambe tailliezi Thi-Ngoc-Dung Nguyen,Omid Feizbakhsh,Estelle Sfecci,Blandine Baratte,Claire Delehouzéet al. Marine drugs, 2019, 17 (10), pp.569. ⟨10.3390/md17100569⟩ Article dans une revue hal-03864501v1
New Antimicrobials Targeting Bacterial RNA Polymerase Holoenzyme Assembly Identified with an &lt;i&gt;in Vivo&lt;/i&gt; BRET-Based Discovery Platform Sara Sartini,Elisabetta Levati,Martina Maccesi,Matteo Guerra,Gilberto Spadoniet al. ACS Chemical Biology, 2019, 14 (8), pp.1727 - 1736. ⟨10.1021/acschembio.9b00178⟩ Article dans une revue hal-03870173v1
Synthesis and evaluation of new isatin-aminorhodanine hybrids as PIM1 and CLK1 kinase inhibitors Khadidja Khaldoun,Abdelmounaim Safer,Nourdine Boukabcha,Necmi Dege,Sandrine Ruchaudet al. Journal of Molecular Structure, 2019, 1192, pp.82 - 90. ⟨10.1016/j.molstruc.2019.04.122⟩ Article dans une revue hal-03870645v1
From Quinoxaline, Pyrido[2,3-b]pyrazine and Pyrido[3,4-b]pyrazine to Pyrazino-Fused Carbazoles and Carbolines Frédéric Lassagne,Timothy Langlais,Elsa Caytan,Emmanuelle Limanton,Ludovic Paquinet al. Molecules, 2018, 23 (11), pp.2961. ⟨10.3390/molecules23112961⟩ Article dans une revue hal-03867783v1
Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors Bruno Oyallon,Marie Brachet-Botineau,Cédric Logé,Pascal Bonnet,Mohamed Souabet al. European Journal of Medicinal Chemistry, 2018, 154, pp.101-109. ⟨10.1016/j.ejmech.2018.04.056⟩ Article dans une revue hal-03408667v1
Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition Hannah Winfield,Michael Cahill,Kevin O'Shea,Larry Pierce,Thomas Robertet al. Bioorganic and Medicinal Chemistry, 2018, 26 (14), pp.4209-4224. ⟨10.1016/j.bmc.2018.07.012⟩ Article dans une revue hal-03011414v1
Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration Viet Hung Dao,Isabelle Ourliac-Garnier,Marc-Antoine Bazin,Catherine Jacquot,Blandine Baratteet al. Bioorganic and Medicinal Chemistry, 2018, 28 (13), pp.2250-2255. ⟨10.1016/j.bmcl.2018.05.044⟩ Article dans une revue hal-03011408v1
2-Aminophenones, a common precursor to N-aryl isatins and acridines endowed with bioactivities Nahida Mokhtari Brikci-Nigassa,Ghenia Bentabed-Ababsa,William Erb,Floris Chevallier,Laurent Picotet al. Tetrahedron, 2018, 74 (15), pp.1785-1801. ⟨10.1016/j.tet.2018.02.038⟩ Article dans une revue hal-01774406v1
Phenytoin inhibits necroptosis Anne von Mässenhausen,Wulf Tonnus,Nina Himmerkus,Simon Parmentier,Danish Salehet al. Cell Death and Disease, 2018, 9 (3), pp.359. ⟨10.1038/s41419-018-0394-3⟩ Article dans une revue hal-03871390v1
A combined experimental and theoretical study of the thermal [3+2] cycloaddition of carbonyl ylides with activated alkenes Samira Hamza-Reguig,Ghenia Bentabed-Ababsa,Luis R Domingo,Mar Ríos-Gutiérrez,Stephanie Philippotet al. Journal of Molecular Structure, 2018, 1157, pp.276-287. ⟨10.1016/j.molstruc.2017.12.052⟩ Article dans une revue hal-01695551v2
Effect of cell cycle arrest on intermediate metabolism in the marine diatom &lt;i&gt;Phaeodactylum tricornutum&lt;/i&gt; Joomi Kim,Christopher M Brown,Min Kyung Kim,Elizabeth H Burrows,Stéphane Bachet al. Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (38), ⟨10.1073/pnas.1711642114⟩ Article dans une revue hal-03875262v1
Bioactive Metabolites from the Deep Subseafloor Fungus Oidiodendron griseum UBOCC-A-114129 Marion Navarri,C. Jégou,Arnaud Bondon,Sandrine Pottier,Stéphane Bachet al. Marine drugs, 2017, 15 (4), ⟨10.3390/md15040111⟩ Article dans une revue hal-01518044v1
Synthesis, docking study and kinase inhibitory activity of a number of new substituted pyrazolo[3,4-c]pyridines Meropi Sklepari,Nikolaos Lougiakis,Athanasios Papastathopoulos,Nicole Pouli,Panagiotis Marakoset al. Chemical and Pharmaceutical Bulletin, 2017, ⟨10.1248/cpb.c16-00704⟩ Article dans une revue hal-03875290v1
Li 2.0 Ni 0.67 N: a promising negative electrode material for Li-ion batteries with a soft structural response Thomas Cavoué,Nicolas Emery,Nurzhan Umirov,Stéphane Bach,Pascal Bergeret al. Inorganic Chemistry, 2017, 56, pp.13815-13821. ⟨10.1021/acs.inorgchem.7b01903⟩ Article dans une revue cea-01626781v1
Fused Systems Based on 2-Aminopyrimidines: Synthesis Combining Deprotolithiation-in situ Zincation with N -Arylation Reactions and Biological Properties Madani Hedidi,Julien Maillard,William Erb,Frédéric Lassagne,Yury S Halaukoet al. European Journal of Organic Chemistry, 2017, 2017 (39), pp.5903-5915. ⟨10.1002/ejoc.201701004⟩ Article dans une revue hal-01624382v1
Screening for Protein-Protein Interaction Inhibitors Using a Bioluminescence Resonance Energy Transfer (BRET)–Based Assay in Yeast Caroline Corbel,Sara Sartini,Elisabetta Levati,Pierre Colas,Laurent Mailletet al. Slas Discovery, 2017, 22 (6), pp.751 - 759. ⟨10.1177/2472555216689530⟩ Article dans une revue hal-03839336v1
Microwave synthesis of new 3-(3-aminopropyl)-5-arylidene-2-thioxo-1,3-thiazolidine-4-ones as potential Ser/Thr protein kinase inhibitors Camille Déliko Dago,Wacothon Karime Coulibaly,Yves-Alain Bekro,Janat A. Mamyrbekova-Bekro,Beatrice Foll-Josselinet al. Medicinal Chemistry Research, 2016, 25 (12), pp.2940--2958. ⟨10.1007/s00044-016-1719-3⟩ Article dans une revue hal-01414293v1
Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells Madani Hedidi,Julien Maillard,William Erb,Frédéric Lassagne,Yury Halaukoet al. Tetrahedron, 2016, 72 (39), pp.6467 - 6476. ⟨10.1016/j.tet.2016.08.056⟩ Article dans une revue hal-03875302v1
Marine Natural Products from New Caledonia—A Review Sofia-Eléna Motuhi,Mohamed Mehiri,Claude Payri,Stéphane La Barre,Stéphane Bach Marine drugs, 2016, 14 (3), pp.58. ⟨10.3390/md14030058⟩ Article dans une revue hal-01292225v1
Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases Camille Déliko Dago,Christelle Ambeu,Wacothon-Karime Coulibaly,Yves-Alain Békro,Janat Mamyrbékovaet al. Molecules, 2015, 20 (7), pp.12412-12435. ⟨10.3390/molecules200712412⟩ Article dans une revue hal-01187427v1
Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1 Espérance Moine,Isabelle Dimier-Poisson,Cécile Enguehard-Gueiffier,Cédric Logé,Mélanie Pénichonet al. European Journal of Medicinal Chemistry, 2015, 105, pp.80-105. ⟨10.1016/j.ejmech.2015.10.004⟩ Article dans une revue istex hal-02389861v1
Tamoxifen Inhibits CDK5 Kinase Activity by Interacting with p35/p25 and Modulates the Pattern of Tau Phosphorylation. Caroline Corbel,Bing Zhang,Annabelle Le Parc,Blandine Baratte,Pierre Colaset al. Chemistry and Biology, 2015, 22 (4), pp.472-482 Article dans une revue hal-01145976v1
Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines Pascal Marchand,Marc-Antoine Bazin,Fabrice Pagniez,Guillaume Rivière,Lizeth Boderoet al. European Journal of Medicinal Chemistry, 2015, 103, pp.381-395. ⟨10.1016/j.ejmech.2015.09.002⟩ Article dans une revue istex hal-03216056v1
Azine and Diazine Functionalization Using 2,2,6,6-Tetramethylpiperidino-Based Lithium–Metal Combinations: Application to the Synthesis of 5,9-Disubstituted Pyrido[3′,2′:4,5]pyrrolo[1,2-c] pyrimidines Nada Marquise,Tan Tai Nguyen,Floris Chevallier,Laurent Picot,Valérie Thiéryet al. SYNLETT, 2015, 26 (20), pp.2811-2816. ⟨10.1055/s-0035-1560496⟩ Article dans une revue hal-01248092v1
A Comparative Insight of Potassium Vanadates as Positive Electrode Materials for Li Batteries: Influence of the Long-Range and Local Structure Rita Baddour-Hadjean,Arezki Boudaoud,Stéphane Bach,Nicolas Emery,Jean Pierre Pereira-Ramos Inorganic Chemistry, 2014, 53 (3), pp.1764-1772. ⟨10.1021/ic402897d⟩ Article dans une revue hal-03131789v1
Bioprospecting Marine Plankton Heni Abida,Sandrine Ruchaud,Laurent Rios,Anne Humeau,Ian Probertet al. Marine drugs, 2013, 11 (11), pp.4594-4611. ⟨10.3390/md11114594⟩ Article dans une revue hal-01258229v1
An in silico approach for the discovery of CDK5/p25 interaction inhibitors. Bing Zhang,Caroline Corbel,Françoise Guéritte,Cyril Couturier,Stéphane Bachet al. Biotechnology Journal, 2011, 6 (7), pp.871-881. ⟨10.1002/biot.201100139⟩ Article dans une revue istex hal-00628754v1
First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors. Caroline Corbel,Qian Wang,Hadjira Bousserouel,Amel Hamdi,Bing Zhanget al. Biotechnology Journal, 2011, 6 (7), pp.860-70. ⟨10.1002/biot.201100138⟩ Article dans une revue istex hal-00628746v1
Identification of potential cellular targets of aloisine A by affinity chromatography. Caroline Corbel,Rose Haddoub,Damien Guiffant,Olivier Lozach,David Gueyrardet al. Bioorganic and Medicinal Chemistry, 2009, 17 (15), pp.5572-82. ⟨10.1016/j.bmc.2009.06.024⟩ Article dans une revue hal-00416033v1
Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions. Déborah Tribouillard-Tanvier,Vincent Béringue,Nathalie Desban,Fabienne Gug,Stéphane Bachet al. PLoS ONE, 2008, 3 (4), pp.e1981. ⟨10.1371/journal.pone.0001981⟩ Article dans une revue hal-00416056v1
Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs Déborah Tribouillard-Tanvier,Suzana dos Reis,Fabienne Gug,Cécile Voisset,Vincent Béringueet al. PLoS ONE, 2008, 3 (5), pp.e2174. ⟨10.1371/journal.pone.0002174⟩ Article dans une revue hal-02134950v1
Identification of intracellular targets of small molecular weight chemical compounds using affinity chromatography. Damien Guiffant,Déborah Tribouillard,Fabienne Gug,Hervé Galons,Laurent Meijeret al. Biotechnology Journal, 2007, 2 (1), pp.68-75. ⟨10.1002/biot.200600223⟩ Article dans une revue hal-00169462v1
Improved tumor control through circadian clock induction by Seliciclib, a cyclin-dependent kinase inhibitor. Ida Iurisci,Elisabeth Filipski,Jens Reinhardt,Stéphane Bach,Athos Gianella-Borradoriet al. Cancer Research, 2006, 66 (22), pp.10720-8. ⟨10.1158/0008-5472.CAN-06-2086⟩ Article dans une revue hal-00169367v1
Using budding yeast to screen for anti-prion drugs Déborah Tribouillard,Stéphane Bach,Fabienne Gug,Nathalie Desban,Vincent Béringueet al. Biotechnology Journal, 2006, 1 (1), pp.58-67. ⟨10.1002/biot.200500001⟩ Article dans une revue istex hal-02660470v1
A yeast-based assay to isolate drugs active against mammalian prions Stéphane Bach,Déborah Tribouillard,Nicolas Talarek,Nathalie Desban,Marc Blondel Methods, 2006, 39 (1), pp.72-77. ⟨10.1016/j.ymeth.2006.04.005⟩ Article dans une revue hal-02134947v1
Roscovitine Targets, Protein Kinases and Pyridoxal Kinase Stéphane Bach,Marie Knockaert,Jens Reinhardt,Olivier Lozach,Sophie Schmittet al. Journal of Biological Chemistry, 2005, 280, pp.31208 - 31219. ⟨10.1074/jbc.m500806200⟩ Article dans une revue hal-03867064v1
Raman investigation of the structural changes in anatase LixTiO2 upon electrochemical lithium insertion Rita Baddour-Hadjean,Stéphane Bach,Mikhail Smirnov,Jean Pierre Pereira-Ramos Journal of Raman Spectroscopy, 2004, 35 (7), pp.577-585. ⟨10.1002/jrs.1200⟩ Article dans une revue istex hal-03131945v1
Isolation of drugs active against mammalian prions using a yeast-based screening assay Stéphane Bach,Nicolas Talarek,Thibault Andrieu,Jean-Michel Vierfond,Yvette Metteyet al. Nature Biotechnology, 2003, 21 (9), pp.1075-1081. ⟨10.1038/nbt855⟩ Article dans une revue hal-02127591v1

Communication dans un congrès (8)

Characterization of electronic conductivity by broadband dielectric spectroscopy of positive electrode materials of spinelle-type Li-ion batteries Mahmoud Aboaouf,Jean-Claude Badot,Olivier Dubrunfaut,Stephane Bach,Nicolas Emery momentom, Apr 2025, Gif-sur-Yvette, France Communication dans un congrès hal-05298109v1
Modifying positions 2 or 8 of the imidazo[1,2-a]pyrazine lead compound CTN1122 affects its antileishmanial activity, L-CK1.2 kinase inhibition, and safety profile Lhana Tisseur,Marc-Antoine Bazin,Sandrine Cojean,Fabrice Pagniez,Cédric Logéet al. GP2A 2024, Aug 2024, Coimbra, Portugal Communication dans un congrès hal-04708945v1
Sibiriline, an inhibitor of regulated necrosis, protects mice against Acetaminophen-induced liver injury, alone or in combination with N-acetyl-cysteine Melanie Simoes Eugenio,Ghiles Imerzoukene,Annaïg Hamon,Claire Piquet-Pellorce,Alison Rapinet al. European-Association-for-the-Study-of-the-Liver Congress (EASL), Jun 2024, Milan, Italy Communication dans un congrès hal-04882056v1
IR transparent Y2O3-MgO nanocomposite ceramic processed by sol-gel synthesis and two-step SPS sintering Nathan Brard,Johan Petit,Benjamin Villeroy,Stéphane Bach SPIE Defense + Commercial Sensing,, Apr 2023, Orlando, United States. ⟨10.1117/12.2663490⟩ Communication dans un congrès hal-04150068v1
Reactivity Under Microwave Irradiation of 2-amino 4H-chromene-3-carbonitrile as tool for the construction of potential bioactive derivatives Ali Bouattour,Mehdi Fakhfakh,Houcine Ammar,Ludovic Paquin,Jean-Pierre Bazureauet al. 3rd International Electronic Conference on Medicinal Chemistry, Nov 2022, Online, France Communication dans un congrès hal-03872422v1
Développement de nouveaux inhibiteurs de TgCDPK1 à visée anti-toxoplasmique Espérance Moine,Isabelle Dimier-Poisson,Cécile Enguehard-Gueiffier,Cedric Logé,Mélanie Pénichonet al. 6. Journées du Consortium antiParasitaire et antiFongique : CaPF-2016 " A la croisée des Mondes !", Consortium Anti-Parasitaire et Fongique (CaPF). FRA., Mar 2016, Tours, France. 49 p Communication dans un congrès hal-02739722v1
Conception, synthèse et évaluation de nouveaux inhibiteurs de TgCDPK1 à visée anti-toxoplasmique Espérance Moine,Isabelle Dimier-Poisson,Cécile Enguehard-Gueiffier,Mélanie Pouvreau,Nathalie Moiréet al. 28. Colloque Biotechnocentre, Biotechnocentre. FRA., Oct 2015, Seillac, France Communication dans un congrès hal-02744066v1
Conception, synthèse et évaluation de nouveaux inhibiteurs de TgCDPK1 à visée anti-toxoplasmique Espérance Moine,Isabelle Dimier-Poisson,Cécile Enguehard-Gueiffier,Cedric Logé,Mélanie Pénichonet al. La journée recherche en Pharmacie, Université de Nantes (UN). FRA., Nov 2015, Nantes, France Communication dans un congrès hal-02796250v1

Poster de conférence (3)

Eimeria tenella ROP kinase 2 induces p38 MAPK cellular pathway Adeline Ribeiro E Silva,Mamadou Diallo,Alix Sausset,Thomas Robert,Stéphane Bachet al. Journées d’Animation Scientifique du Département Santé Animale (JAS SA), Oct 2022, Anglet, France. Poster de conférence hal-03852796v1
Eimeria tenella induces p38 MAPK signalling pathway Adeline Ribeiro E Silva,Mamadou Diallo,Alix Sausset,Thomas Robert,Stéphane Bachet al. Journées d'Animation Scientifique de la FéRI 2022- FéRI Scientific Days 2022, Région Centre Val de Loire, Jul 2022, Tours, France Poster de conférence hal-03735655v1
Conception, synthèse et évaluation de nouveaux inhibiteurs de TgCDPK1 à visée anti-toxoplasmique Espérance Moine,Isabelle Dimier-Poisson,Cécile Enguehard-Gueiffier,Mélanie Pouvreau,Nathalie Moiréet al. Days of the Research Federation in Infectious Diseases, Oct 2015, Orléans, France. 2015 Poster de conférence hal-02793392v1

Pré-publication, Document de travail (1)

Nigratine as first-in-class dual inhibitor of necroptosis and ferroptosis regulated cell death Claire Delehouzé,Arnaud Comte,Marcelle Hauteville,Peter G Goekjian,Marie-Thérèse Dimanche-Boitrelet al. 2022 Pré-publication, Document de travail (preprint/prepublication) hal-03867390v1

Chapitre d'ouvrage (3)

Marine dinoflagellates as a source of new bioactive structures Arnaud Cousseau,Raffaele Siano,Ian Probert,Stéphane Bach,Mohamed Mehiri Studies in Natural Products Chemistry, 65, 2022, Bioactive Natural Products, ⟨10.1016/B978-0-12-817905-5.00004-4⟩ Chapitre d'ouvrage hal-03867411v1
Marine Pigment Diversity: Applications and Potential Benoît Serive,Stéphane Bach Blue Biotechnology - Production and Use of Marine Molecules, Wiley-VCH Verlag GmbH & Co. KGaA, pp.643-681, 2018, ⟨10.1002/9783527801718.ch20⟩ Chapitre d'ouvrage hal-03871338v1
High-Throughput Screening of marine resources Arnaud Hochard,Luc Reininger,Sandrine Ruchaud,Stéphane Bach Outstanding Marine Molecules, 2015, ⟨10.1002/9783527681501.ch23⟩ Chapitre d'ouvrage hal-03871307v1

Brevet (3)

Natural Product Derivatives For Inhibiting Cellular Necroptosis, Ferroptosis And Oxytosis Stéphane Bach,Marie-Thérèse Dimanche-Boitrel,Claire Delehouzé,Thierry Hauet United States, Patent n° : US 2022/0096426 A1. 2022 Brevet hal-03870690v1
N1- and N7-substituted sibiriline derivatives and their use as inhibitor of cellular necroptosis. Marie-Thérèse Dimanche-Boitrel,Stéphane Bach,Claire Delehouze,Peter Goekjian,Arnaud Comte France, Patent n° : WO2017064216. CO2GLYCO : Equipe de Chimie Organique 2-Glycochimie. 2017 Brevet hal-01545901v1
Sibiriline derivatives for use for preventing and/or treating disorders associated with cellular necroptosis. Marie-Thérèse Dimanche-Boitrel,Stéphane Bach,Claire Delehouze,Yvette Mettey,Peter Goekjianet al. France, Patent n° : WO/2017/064217. CO2GLYCO : Equipe de Chimie Organique 2-Glycochimie. 2017 Brevet hal-01545878v1