stéphanie lagadu

23
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Publications

Publications

Blood contamination of the pharmaceutical staff by irinotecan and its two major metabolites inside and outside a compounding unit

Victoire Béchet , Hubert Benoist , Frédéric Beau , Fabienne Divanon , Stéphanie Lagadu et al.
Journal of Oncology Pharmacy Practice, 2022, 28 (4), pp.777-784. ⟨10.1177/10781552211012059⟩
Article dans une revue hal-03593465 v1
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Investigation by mass spectrometry and 32P post-labelling of DNA adducts formation from 1,2-naphthoquinone, an oxydated metabolite of naphthalene

Adeline Clergé , Jérémie Le Goff , Claire Lopez-Piffet , Sonnich Meier , Stéphanie Lagadu et al.
Chemosphere, 2021, 263, pp.128079. ⟨10.1016/j.chemosphere.2020.128079⟩
Article dans une revue hal-03022040 v1
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Is the blood of a surgeon performing HIPEC contaminated by irinotecan, its major metabolites and platinum compounds?

Guillaume Saint-Lorant , Simon Rodier , Jean-Marc Guilloit , Sophie Ndaw , Mathieu Melczer et al.
Pleura and peritoneum, 2021, 6 (2), pp.49-55. ⟨10.1515/pp-2020-0141⟩
Article dans une revue hal-03593461 v1

Antipsychotic lurasidone: Behavioural and pharmacokinetic data in C57BL/6 mice

Solenn Percelay , Marc Since , S. Lagadu , Thomas Freret , Valentine Bouet et al.
Pharmacology Biochemistry and Behavior, 2020, 194, pp.172933. ⟨10.1016/j.pbb.2020.172933⟩
Article dans une revue hal-03602034 v1
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A validated UHPLC-MS/MS method for simultaneous quantification of 9 exocyclic DNA adducts induced by 8 aldehydes

Helena Alamil , Mathilde Lechevrel , Stéphanie Lagadu , Laurence Galanti , Zeina Dagher et al.
Journal of Pharmaceutical and Biomedical Analysis, 2020, 179, pp.113007. ⟨10.1016/j.jpba.2019.113007⟩
Article dans une revue hal-02461102 v1
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Production of early and late nuclear DNA damage and extracellular 8- oxodG in normal human skin fibroblasts after carbon ion irradiation compared to X-rays

Virginie Prevost , François Sichel , Ivannah Pottier , Alexandre Leduc , Stéphanie Lagadu et al.
Toxicology in Vitro, 2018, 52, pp.116-121. ⟨10.1016/j.tiv.2018.06.004⟩
Article dans une revue inserm-02181592 v1

Impact of after-treatment devices and biofuels on diesel exhausts genotoxicity in A549 cells exposed at air-liquid interface

Claire Barraud , Cécile Corbière , I. Pottier , E. Estace , K. Blanchard et al.
Toxicology in Vitro, 2017, 45 (Part 3), pp.426-433. ⟨10.1016/j.tiv.2017.04.025⟩
Article dans une revue hal-02025402 v1

Effects of alcohol consumption on biomarkers of oxidative damage to DNA and lipids in ethanol-fed pigs

F. Petitpas , F. Sichel , B. Hébert , S. Lagadu , M. Beljean et al.
Experimental and Toxicologic Pathology, 2013, 65 (3), pp.263-269. ⟨10.1016/j.etp.2011.09.001⟩
Article dans une revue hal-03602040 v1

Detection of extracellular 8-oxo-7,8-dihydro-2′-deoxyguanosine as a biomarker of oxidative damage in X-irradiated fibroblast cultures: optimization of analytical procedure

Stéphanie Lagadu , Ivannah Pottier , François Sichel , Carine Laurent , Jean-Louis Lefaix et al.
Biomarkers, 2010, 15 (8), pp.707-714. ⟨10.3109/1354750X.2010.511269⟩
Article dans une revue hal-02297398 v1
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8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST

Stéphanie Lagadu , Mathilde Lechevrel , François Sichel , Jean Breton , Didier Pottier et al.
Journal of experimental & clinical cancer research, 2010, 29 (1), pp.157. ⟨10.1186/1756-9966-29-157⟩
Article dans une revue hal-02461268 v1

Estimation semi-quantitative de la concentration sans calibration par modélisation moléculaire et Machine-learning à partir de données LC-MS. Exemple d’application et perspective

Quentin Vandoolaeghe , Valérie Bouchart , Isabelle Vaudorne , S. Lagadu , Raphael Delepee
Ecole thématique club jeune AFSEP « Une plongée captivante dans l’univers des Omics », May 2024, Lavandou, France
Communication dans un congrès hal-04769372 v1

Automatisation de la préparation d’échantillons biologiques pour une analyse haut débit en LC-MS/MS adaptée aux cohortes : Défis et opportunités

Quentin Vandoolaeghe , Valérie Bouchart , Yolaine Guerin , S. Lagadu , Raphael Delepee
Club de Chromatographie du Val de Seine, Association Francophone des Sciences Séparatives, Apr 2024, Rouen, France
Communication dans un congrès hal-04769379 v1

Determination of unknown concentrations without calibration curve by modelling molecules ionisation in LC-MS through machine learning

Quentin Vandoolaeghe , S. Lagadu , Yolaine Guerin , Valérie Bouchart , Raphael Delepee
18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, May 2024, Leuven, Belgium
Communication dans un congrès hal-04769363 v1

Adductomics: How DNA adducts can be useful tools from toxicology to exposome determination

Quentin Vandoolaeghe , A. Clergé , S. Lagadu , I. Catro , C. Piffet et al.
Congrès ANALYTICS, Sep 2022, Nantes, France
Communication dans un congrès hal-03846734 v1

Optimisation d’une méthode HPLC-MS/MS d’analyse robuste de marqueurs épigénétiques par la modification d’une phase stationnaire de carbone graphite poreux

Quentin Vandoolaeghe , Valérie Bouchart , Isabelle Vaudorne , S. Lagadu , Raphael Delepee
Club de Chromatographie du Val de Seine, Association Francophone des Sciences Séparatives, Dec 2022, Caen, France
Communication dans un congrès hal-04769507 v1

Stratégie pour le criblage de l’exposition humaine à des composés génotoxiques

Adeline Clergé , Jérémie Le Goff , Isabelle Vaudorne , Stéphanie Lagadu , Raphaël Delépée
Club Chromatographie Val-de-Seine, Valérie Agasse; Pascal Cardinaël, Jun 2019, Deauville, France
Communication dans un congrès hal-02477741 v1

Synthesis and characterization by UHPLC-MS/MS of DNA adducts from 4 oxy-PAHs for the evaluation of their genotoxicity

Adeline Clergé , Jérémie Le Goff , Isabelle Vaudorne , Stéphanie Lagadu , Raphaël Delépée
HPLC2019, Jun 2019, Milan, Italy
Communication dans un congrès hal-02477807 v1

Pharmacokinetic and safety of a novel pleiotropic compound in C57BL/6J mice with potential therapeutic interest in Alzheimer’s disease

Caroline Lahogue , Stacy Largilliere , Gérald Nee , Alice Wang , Stéphanie Lagadu et al.
FENS 2024, Jun 2024, Vienne, Austria
Poster de conférence hal-04632974 v1

Synthèse et caractérisation par UHPLC-MS/MS d’adduits entre l’ADN et 7 oxy-HAP pour l’évaluation de leur génotoxicité

Adeline Clergé , Jérémie Le Goff , Isabelle Vaudorne , Stéphanie Lagadu , Raphaël Delépée
SEP 2019 - 13ème congrès francophone sur les sciences séparatives et les couplages de l'AFSEP, Mar 2019, Paris, France
Poster de conférence hal-02477612 v1

Study of the genotoxicity of 7 oxy-PAHs: focus on DNA adducts

Adeline Clergé , Jérémie Le Goff , Émilie Brotin , Isabelle Vaudorne , Stéphanie Lagadu et al.
EEMGS, May 2019, Rennes, France
Poster de conférence hal-02477637 v1

Evaluation of genotoxicity and mutagenicity of 1,2-naphthoquinone

Adeline Clergé , Jérémie Le Goff , Stéphanie Lagadu , Isabelle Vaudorne , Raphaël Delépée
Journée Normande de Recherche Biomédicale, Sep 2018, Rouen, France
Poster de conférence hal-02477535 v1

Synthesis, characterization and quantification by UHPLC-MS/MS of DNA adducts from 5 oxy-PAHs for the evaluation of their genotoxicity

Adeline Clergé , Jérémie Le Goff , Isabelle Vaudorne , Stéphanie Lagadu , Raphaël Delépée
32nd International Symposium on Chromatography ISC 2018, Sep 2018, Cannes - Mandelieu, France
Poster de conférence hal-02477589 v1

Oxidative stress induction and genotoxicity of diesel exhausts on A549 lung cells continuously exposed at the air-liquid interface. Impact of rapeseed methyl ester supplementation and of after treatment devices: oxidation catalyst and particulate filter.

Claire Barraud , Cécile Corbière , Ivannah Pottier , Emmanuelle Estace , K. Blanchard et al.
19th International Congress on In Vitro Toxicology European Society of Toxicology In Vitro (ESTIV) - "In Vitro Toxicology for Human Safety Assessment", Oct 2016, Antibes Juan-les-Pins, France
Poster de conférence hal-02470096 v1