stéphanie lagadu

Présentation

Publications

Article dans une revue (10)

Blood contamination of the pharmaceutical staff by irinotecan and its two major metabolites inside and outside a compounding unit Victoire Béchet,Hubert Benoist,Frédéric Beau,Fabienne Divanon,Stéphanie Lagaduet al. Journal of Oncology Pharmacy Practice, 2022, 28 (4), pp.777-784. ⟨10.1177/10781552211012059⟩ Article dans une revue hal-03593465v1
Investigation by mass spectrometry and 32P post-labelling of DNA adducts formation from 1,2-naphthoquinone, an oxydated metabolite of naphthalene Adeline Clergé,Jérémie Le Goff,Claire Lopez-Piffet,Sonnich Meier,Stéphanie Lagaduet al. Chemosphere, 2021, 263, pp.128079. ⟨10.1016/j.chemosphere.2020.128079⟩ Article dans une revue hal-03022040v1
Is the blood of a surgeon performing HIPEC contaminated by irinotecan, its major metabolites and platinum compounds? Guillaume Saint-Lorant,Simon Rodier,Jean-Marc Guilloit,Sophie Ndaw,Mathieu Melczeret al. Pleura and peritoneum, 2021, 6 (2), pp.49-55. ⟨10.1515/pp-2020-0141⟩ Article dans une revue hal-03593461v1
Antipsychotic lurasidone: Behavioural and pharmacokinetic data in C57BL/6 mice Solenn Percelay,Marc Since,S. Lagadu,Thomas Freret,Valentine Bouetet al. Pharmacology Biochemistry and Behavior, 2020, 194, pp.172933. ⟨10.1016/j.pbb.2020.172933⟩ Article dans une revue hal-03602034v1
A validated UHPLC-MS/MS method for simultaneous quantification of 9 exocyclic DNA adducts induced by 8 aldehydes Helena Alamil,Mathilde Lechevrel,Stéphanie Lagadu,Laurence Galanti,Zeina Dagheret al. Journal of Pharmaceutical and Biomedical Analysis, 2020, 179, pp.113007. ⟨10.1016/j.jpba.2019.113007⟩ Article dans une revue hal-02461102v1
Production of early and late nuclear DNA damage and extracellular 8- oxodG in normal human skin fibroblasts after carbon ion irradiation compared to X-rays Virginie Prevost,François Sichel,Ivannah Pottier,Alexandre Leduc,Stéphanie Lagaduet al. Toxicology in Vitro, 2018, 52, pp.116-121. ⟨10.1016/j.tiv.2018.06.004⟩ Article dans une revue inserm-02181592v1
Impact of after-treatment devices and biofuels on diesel exhausts genotoxicity in A549 cells exposed at air-liquid interface Claire Barraud,Cécile Corbière,I. Pottier,E. Estace,K. Blanchardet al. Toxicology in Vitro, 2017, 45 (Part 3), pp.426-433. ⟨10.1016/j.tiv.2017.04.025⟩ Article dans une revue hal-02025402v1
Effects of alcohol consumption on biomarkers of oxidative damage to DNA and lipids in ethanol-fed pigs F. Petitpas,F. Sichel,B. Hébert,S. Lagadu,M. Beljeanet al. Experimental and Toxicologic Pathology, 2013, 65 (3), pp.263-269. ⟨10.1016/j.etp.2011.09.001⟩ Article dans une revue istex hal-03602040v1
8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST Stéphanie Lagadu,Mathilde Lechevrel,François Sichel,Jean Breton,Didier Pottieret al. Journal of experimental & clinical cancer research, 2010, 29 (1), pp.157. ⟨10.1186/1756-9966-29-157⟩ Article dans une revue hal-02461268v1
Detection of extracellular 8-oxo-7,8-dihydro-2′-deoxyguanosine as a biomarker of oxidative damage in X-irradiated fibroblast cultures: optimization of analytical procedure Stéphanie Lagadu,Ivannah Pottier,François Sichel,Carine Laurent,Jean-Louis Lefaixet al. Biomarkers, 2010, 15 (8), pp.707-714. ⟨10.3109/1354750X.2010.511269⟩ Article dans une revue hal-02297398v1

Communication dans un congrès (9)

Use of DNA adducts formed from aldehydes as biomarkers of oxidative stress effects associated with agricultural work activities Raphael Delepee,Quentin Vandoolaeghe,Yolaine Guérin,Stéphanie Lagadu,Claire Lopez-Piffetet al. 30th Epidemiology in Occupational Health Conference (EPICOH 2025), Institute for Risk Assessment Sciences, Utrecht University, Oct 2025, Utrecht (Netherlands), Netherlands Communication dans un congrès hal-05349230v1
Automatisation de la préparation d’échantillons biologiques pour une analyse haut débit en LC-MS/MS adaptée aux cohortes : Défis et opportunités Quentin Vandoolaeghe,Valérie Bouchart,Yolaine Guerin,S. Lagadu,Raphael Delepee Club de Chromatographie du Val de Seine, Association Francophone des Sciences Séparatives, Apr 2024, Rouen, France Communication dans un congrès hal-04769379v1
Estimation semi-quantitative de la concentration sans calibration par modélisation moléculaire et Machine-learning à partir de données LC-MS. Exemple d’application et perspective Quentin Vandoolaeghe,Valérie Bouchart,Isabelle Vaudorne,S. Lagadu,Raphael Delepee Ecole thématique club jeune AFSEP « Une plongée captivante dans l’univers des Omics », May 2024, Lavandou, France Communication dans un congrès hal-04769372v1
Determination of unknown concentrations without calibration curve by modelling molecules ionisation in LC-MS through machine learning Quentin Vandoolaeghe,S. Lagadu,Yolaine Guerin,Valérie Bouchart,Raphael Delepee 18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, May 2024, Leuven, Belgium Communication dans un congrès hal-04769363v1
Characterization of GtH-independent endocrine GnRH signaling in the testis of the small-spotted catshark Scyliorhinus canicula: a direct ancestral role for GnRH isoforms in the control of spermatogenesis and steroidogenesis in early vertebrates Fabian Jeanne,Stanislas Pilet,Benoit Bernay,S. Lagadu,Raphaël Delépéeet al. 31st Conference of the European Society for Comparative Endocrinology (CECE), Sep 2024, Ancona, Italy Communication dans un congrès hal-05556480v1
Optimisation d’une méthode HPLC-MS/MS d’analyse robuste de marqueurs épigénétiques par la modification d’une phase stationnaire de carbone graphite poreux Quentin Vandoolaeghe,Valérie Bouchart,Isabelle Vaudorne,S. Lagadu,Raphael Delepee Club de Chromatographie du Val de Seine, Association Francophone des Sciences Séparatives, Dec 2022, Caen, France Communication dans un congrès hal-04769507v1
Adductomics: How DNA adducts can be useful tools from toxicology to exposome determination Quentin Vandoolaeghe,A. Clergé,S. Lagadu,I. Catro,C. Piffetet al. Congrès ANALYTICS, Sep 2022, Nantes, France Communication dans un congrès hal-03846734v1
Synthesis and characterization by UHPLC-MS/MS of DNA adducts from 4 oxy-PAHs for the evaluation of their genotoxicity Adeline Clergé,Jérémie Le Goff,Isabelle Vaudorne,Stéphanie Lagadu,Raphaël Delépée HPLC2019, Jun 2019, Milan, Italy Communication dans un congrès hal-02477807v1
Stratégie pour le criblage de l’exposition humaine à des composés génotoxiques Adeline Clergé,Jérémie Le Goff,Isabelle Vaudorne,Stéphanie Lagadu,Raphaël Delépée Club Chromatographie Val-de-Seine, Valérie Agasse; Pascal Cardinaël, Jun 2019, Deauville, France Communication dans un congrès hal-02477741v1

Poster de conférence (7)

Association between occupational agricultural exposures and epigenetic modifications in DNA from granulocytes in a french agricultural worker population Quentin Vandoolaeghe,Valerie Bouchart,Yolaine Guérin,Stéphanie Lagadu,Claire Lopez-Piffetet al. 30th Epidemiology in Occupational Health Conference (EPICOH 2025), Oct 2025, Utrecht (Netherlands), Netherlands Poster de conférence hal-05349268v1
Pharmacokinetic and safety of a novel pleiotropic compound in C57BL/6J mice with potential therapeutic interest in Alzheimer’s disease Caroline Lahogue,Stacy Largilliere,Gérald Nee,Alice Wang,Stéphanie Lagaduet al. FENS 2024, Jun 2024, Vienne, Austria Poster de conférence hal-04632974v1
Study of the genotoxicity of 7 oxy-PAHs: focus on DNA adducts Adeline Clergé,Jérémie Le Goff,Émilie Brotin,Isabelle Vaudorne,Stéphanie Lagaduet al. EEMGS, May 2019, Rennes, France Poster de conférence hal-02477637v1
Synthèse et caractérisation par UHPLC-MS/MS d’adduits entre l’ADN et 7 oxy-HAP pour l’évaluation de leur génotoxicité Adeline Clergé,Jérémie Le Goff,Isabelle Vaudorne,Stéphanie Lagadu,Raphaël Delépée SEP 2019 - 13ème congrès francophone sur les sciences séparatives et les couplages de l'AFSEP, Mar 2019, Paris, France Poster de conférence hal-02477612v1
Evaluation of genotoxicity and mutagenicity of 1,2-naphthoquinone Adeline Clergé,Jérémie Le Goff,Stéphanie Lagadu,Isabelle Vaudorne,Raphaël Delépée Journée Normande de Recherche Biomédicale, Sep 2018, Rouen, France Poster de conférence hal-02477535v1
Synthesis, characterization and quantification by UHPLC-MS/MS of DNA adducts from 5 oxy-PAHs for the evaluation of their genotoxicity Adeline Clergé,Jérémie Le Goff,Isabelle Vaudorne,Stéphanie Lagadu,Raphaël Delépée 32nd International Symposium on Chromatography ISC 2018, Sep 2018, Cannes - Mandelieu, France Poster de conférence hal-02477589v1
Oxidative stress induction and genotoxicity of diesel exhausts on A549 lung cells continuously exposed at the air-liquid interface. Impact of rapeseed methyl ester supplementation and of after treatment devices: oxidation catalyst and particulate filter. Claire Barraud,Cécile Corbière,Ivannah Pottier,Emmanuelle Estace,K. Blanchardet al. 19th International Congress on In Vitro Toxicology European Society of Toxicology In Vitro (ESTIV) - "In Vitro Toxicology for Human Safety Assessment", Oct 2016, Antibes Juan-les-Pins, France Poster de conférence hal-02470096v1