Thibaut Douché

32
Documents

Présentation

2003: Brevet de Technicien Supérieur - Biochimiste (Académie de Lille)

2008: MASTER - Biochimie Structurale, Protéomique et Métabolomique (Académie de Toulouse)

2008/2009: Institut de Pharmacologie et de Biologie Structurale CNRS/UMR5089 (Toulouse) - Laboratoire de Protéomique et Spectrométrie de Masse des Biomolécules.

2009/2012: Laboratoire de Recherche en Sciences Végétales CNRS/UMR5546 (Castanet-Tolosan) - Equipe Protéines Pariétales et Développement.

2011/2015: Centre de Recherche en Cancérologie de Toulouse INSERM/U1037 (Toulouse) - Equipe Signalisation PI3K et Contrôle Traductionnel dans les Tumeurs Pancréatiques et Hypophysaires.

2015-2021: Institut Pasteur (Paris) - Unité de Technologie et de Service Spectrométrie de Masse pour la Biologie (UTechS MSBio)

Publications

Publications

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Biogenesis of DNA-carrying extracellular vesicles by the dominant human gut methanogenic archaeon

Diana P Baquero , Guillaume Borrel , Anastasia Gazi , Camille Martin-Gallausiaux , Virginija Cvirkaite-Krupovic et al.
Nature Communications, 2025, 16 (1), pp.5093. ⟨10.1038/s41467-025-60272-9⟩
Article dans une revue pasteur-05097185 v1
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A Multiyear Longitudinal Harmonization Study of Quality Controls in Mass Spectrometry Proteomics Core Facilities

Cristina Chiva , Roger Olivella , An Staes , Teresa Mendes Maia , Christian Panse et al.
Journal of Proteome Research, 2025, 24 (2), pp.397-409. ⟨10.1021/acs.jproteome.4c00359⟩
Article dans une revue pasteur-05076146 v1
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Profiling Cullin4-E3 Ligases Interactomes and Their Rewiring in Influenza A Virus Infection

Guillaume Dugied , Thibaut Douche , Melanie dos Santos , Quentin Giai Gianetto , Camille Cassonnet et al.
Molecular and Cellular Proteomics, 2024, 23 (11), pp.100856. ⟨10.1016/j.mcpro.2024.100856⟩
Article dans une revue pasteur-04854515 v1
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The extent of postpartum cardiac reverse remodeling is reflected in urine proteome

Ana F Ferreira , Fábio Trindade , Maria J Azevedo , Juliana Morais , Thibaut Douché et al.
Scientific Reports, 2024, 14 (1), pp.14815. ⟨10.1038/s41598-024-65612-1⟩
Article dans une revue pasteur-05076147 v1
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Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease

Alejandro Tejada-Arranz , Aleksei Lulla , Maxime Bouilloux-Lafont , Evelyne Turlin , Xue-Yuan Pei et al.
Nature Communications, 2023, 14 (1), pp.8072. ⟨10.1038/s41467-023-43825-8⟩
Article dans une revue hal-04612500 v1
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RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness

Anna Griego , Thibaut Douché , Quentin Giai Gianetto , Mariette Matondo , Giulia Manina
iScience, 2022, 25 (5), pp.104233. ⟨10.1016/j.isci.2022.104233⟩
Article dans une revue pasteur-03693876 v1
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Amphiregulin mediates non-cell-autonomous effect of senescence on reprogramming

Mathieu von Joest , Cheng Chen , Thibaut Douché , Jérémy Chantrel , Aurélie Chiche et al.
Cell Reports, 2022, 40 (2), pp.111074. ⟨10.1016/j.celrep.2022.111074⟩
Article dans une revue pasteur-04093575 v1
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Proteomic Analysis Uncovers Measles Virus Protein C Interaction With p65–iASPP Protein Complex

Alice Meignié , Chantal Combredet , Marc Santolini , István Kovács , Thibaut Douché et al.
Molecular and Cellular Proteomics, 2021, 20, pp.100049. ⟨10.1016/j.mcpro.2021.100049⟩
Article dans une revue pasteur-03184181 v1
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Quality standards in proteomics research facilities

Cristina Chiva , Teresa Mendes Maia , Christian Panse , Karel Stejskal , Thibaut Douché et al.
EMBO Reports, 2021, 22 (6), pp.e52626. ⟨10.15252/embr.202152626⟩
Article dans une revue pasteur-03258884 v1
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RNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori

Alejandro Tejada Arranz , Rute G Matos , Yves Quentin , Maxime Bouilloux-Lafont , Eloïse Galtier et al.
Nucleic Acids Research, 2021, 49 (9), pp.5249-5264. ⟨10.1093/nar/gkab283⟩
Article dans une revue pasteur-03242387 v1
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Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance

C Cintas , T Douche , Z Dantes , Emmanuelle Mouton-Barbosa , Marie-Pierre Bousquet et al.
Molecular Cancer Therapeutics, 2021, ⟨10.1158/1535-7163.MCT-20-0981⟩
Article dans une revue hal-03223423 v1
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Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With Macrophages

Rémi Samain , Alexia Brunel , Thibaut Douché , Marjorie Fanjul , Stéphanie Cassant-Sourdy et al.
Cellular and Molecular Gastroenterology and Hepatology, 2021, 11 (5), pp.1405-1436. ⟨10.1016/j.jcmgh.2021.01.008⟩
Article dans une revue pasteur-03252986 v1
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Cell wall proteomic datasets of stems and leaves of Brachypodium distachyon

Thibaut Douché , Benoît Valot , Thierry Balliau , Hélène San Clemente , Michel Zivy et al.
Data in Brief, 2021, 35, pp.1-4. ⟨10.1016/j.dib.2021.106818⟩
Article dans une revue (data paper) hal-03259235 v1
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CYP450 core involvement in multiple resistance strains of Aedes aegypti from French Guiana highlighted by proteomics, molecular and biochemical studies

Yanouk Epelboin , Lanjiao Wang , Quentin Giai Gianetto , Valérie Choumet , Pascal Gaborit et al.
PLoS ONE, 2021, 16 (1), pp.e0243992. ⟨10.1371/journal.pone.0243992⟩
Article dans une revue pasteur-03184205 v1
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Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile

Transito Garcia-Garcia , Sandrine Poncet , Elodie Cuenot , Thibaut Douché , Quentin Giai Gianetto et al.
mBio, 2021, 12 (3), pp.e00519-21. ⟨10.1128/mBio.00519-21⟩
Article dans une revue pasteur-03243540 v1

Disorder-To-Order Transitions and Post-Translational Acylation Control the Folding and Activity of the Bordetella Pertussis CyaA Toxin

Darragh P. O'Brien , Alexis Voegele , Dorothee Raoux-Barbot , Marilyne Davi , Sara Cannella et al.
Biophysical Journal, 2020, 118 (3), pp.197A--197A. ⟨10.1016/j.bpj.2019.11.1189⟩
Article dans une revue hal-02516165 v1
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The Flemmingsome reveals an ESCRT-to-membrane coupling via ALIX/syntenin/syndecan-4 required for completion of cytokinesis

Cyril Addi , Adrien Presle , Stéphane Frémont , Frédérique Cuvelier , Murielle Rocancourt et al.
Nature Communications, 2020, 11 (1), pp.1941. ⟨10.1038/s41467-020-15205-z⟩
Article dans une revue pasteur-02557366 v1

CotL, a new morphogenetic spore coat protein of Clostridium difficile

Carolina Alves Feliciano , Thibaut Douche , Quentin Giai Gianetto , Mariette I Matondo , Isabelle Martin-Verstraete et al.
Environmental Microbiology, 2019, 21 (3), pp.984-1003. ⟨10.1111/1462-2920.14505⟩
Article dans une revue pasteur-02331056 v1

Post-translational acylation controls the folding and functions of the CyaA RTX toxin

Darragh O'Brien , Sara E Cannella , Alexis Voegele , Dorothée Raoux-Barbot , Marilyne Davi et al.
FASEB Journal, 2019, 33 (9), pp.10065-10076. ⟨10.1096/fj.201802442RR⟩
Article dans une revue pasteur-02330713 v1
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The Ser/Thr kinase PrkC participates in cell wall homeostasis and antimicrobial resistance in Clostridium difficile

Elodie Cuenot , Transito Garcia-Garcia , Thibaut Douche , Olivier Gorgette , Pascal Courtin et al.
Infection and Immunity, 2019, 87 (8), pp.e00005-19. ⟨10.1128/IAI.00005-19⟩
Article dans une revue pasteur-02164685 v1
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The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro

Alexis Voegele , Mirko Sadi , Dorothée Raoux-Barbot , Thibaut Douche , Mariette Matondo et al.
Toxins, 2019, Special Issue RTX Toxins, 11 (2), pp.111. ⟨10.3390/toxins11020111⟩
Article dans une revue pasteur-02329482 v1
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Signal-Targeted Therapies and Resistance Mechanisms in Pancreatic Cancer: Future Developments Reside in Proteomics

Celia Cintas , Thibaut Douche , Nicole Therville , Silvia Arcucci , Fernanda Ramos-Delgado et al.
Cancers, 2018, 10 (6), pp.174. ⟨10.3390/cancers10060174⟩
Article dans une revue hal-02500132 v1
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Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates

Valerie Bouchez , Thibaut Douche , Mélody Dazas , Sophie Delaplane , Mariette Matondo et al.
Toxins, 2017, 9 (10), pp.304. ⟨10.3390/toxins9100304⟩
Article dans une revue pasteur-02573143 v1
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Proteome remodelling by the stress sigma factor RpoS/σS in Salmonella: identification of small proteins and evidence for post-transcriptional regulation

Magali Lago , Véronique Monteil , Thibaut Douche , Julien Guglielmini , Alexis Criscuolo et al.
Scientific Reports, 2017, 7, pp.2127. ⟨10.1038/s41598-017-02362-3⟩
Article dans une revue pasteur-01540240 v1
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Cell wall proteome of sugarcane stems: comparison of a destructive and a non-destructive extraction method showed differences in glycoside hydrolases and peroxidases

Maria Juliana Calderan-Rodrigues , Elisabeth Jamet , Thibaut Douché , Maria Beatriz Rodrigues Bonassi , Thaís Regiani Cataldi et al.
BMC Plant Biology, 2016, 16 (1), pp.14. ⟨10.1186/s12870-015-0677-0⟩
Article dans une revue hal-03259237 v1

<em>Brachypodium distachyon</em> as a model plant toward improved biofuel crops: search for secreted proteins involved in biogenesis and disassembly of cell wall polymers

Thibaut Douche , Hélène San Clemente , Vincent Burlat , David Roujol , Benoit B. Valot et al.
Proteomics, 2013, 13 (16), pp.2438-2454. ⟨10.1002/pmic.201200507⟩
Article dans une revue istex hal-02647765 v1

Diagnostic value and prognostic significance of plasmatic proteasome level in patients with melanoma

Laurent Henry , Thierry Lavabre-Bertrand , Thibaut Douche , Sandrine Uttenweiler-Joseph , Pascale Fabbro-Peray et al.
Experimental Dermatology, 2010, 19 (12), pp.1054-1059. ⟨10.1111/j.1600-0625.2010.01151.x⟩
Article dans une revue istex hal-02503539 v1
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Applying Reverse Genetics to Study Measles Virus Interactions with the Host

Heidy Vera-Peralta , Valérie Najburg , Chantal Combredet , Thibaut Douché , Quentin Giai Gianetto et al.
Dzwokai Z. Ma; Christian K. Pfaller. Measles and Related Morbilliviruses: Methods and Protocols, 2808, Springer, pp.89-103, 2024, Methods in Molecular Biology, 978-1-0716-3870-5 (eBook). ⟨10.1007/978-1-0716-3870-5_7⟩
Chapitre d'ouvrage hal-04638406 v1