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Thierry Soussi




Letter’s to the editor

Thierry Soussi
Human Molecular Genetics, 2023, ⟨10.1093/hmg/ddad037⟩
Journal articles hal-04028481v1
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The Broad Spectrum of TP53 Mutations in CLL: Evidence of Multiclonality and Novel Mutation Hotspots

Grégory Lazarian , Bernard Leroy , Floriane Theves , Myriam Hormi , Rémi Letestu
Human Mutation, 2023, 2023, pp.1-17. ⟨10.1155/2023/4880113⟩
Journal articles hal-04147818v1

Benign SNPs in the Coding Region of TP53 : Finding the Needles in a Haystack of Pathogenic Variants

Thierry Soussi
Cancer Research, 2022, 82 (19), pp.3420-3431. ⟨10.1158/0008-5472.CAN-22-0172⟩
Journal articles hal-04028476v1
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Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog

Qiang Zhang , Dimitrios-Ilias Balourdas , Bruno Baron , Alon Senitzki , Tali E Haran
Cell Death and Disease, 2022, 13 (3), pp.214. ⟨10.1038/s41419-022-04653-8⟩
Journal articles hal-03974958v1
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TP53 mutations at codon 234 are associated with chlorambucil treatment in chronic lymphocytic leukemia

Grégory Lazarian , Floriane Theves , Myriam Hormi , Rémi Letestu , Virginie Eclache
American Journal of Hematology, 2022, 97 (4), pp.E159-E162. ⟨10.1002/ajh.26479⟩
Journal articles hal-03557401v1
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Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene

Flora Doffe , Vincent Carbonnier , Manon Tissier , Bernard Leroy , Isabelle Martins
Cell Death and Differentiation, 2020, ⟨10.1038/s41418-020-00672-0⟩
Journal articles hal-03095188v1
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Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network

Sue Haupt , Franco Caramia , Alan Herschtal , Thierry Soussi , Guillermina Lozano
Nature Communications, 2019, 10, pp.5385. ⟨10.1038/s41467-019-13266-3⟩
Journal articles hal-02406712v1
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Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan

Jesse J Salk , Kaitlyn Loubet-Senear , Elisabeth Maritschnegg , Charles Valentine , Lindsey Williams
Cell Reports, 2019, 28 (1), pp.132-144.e3. ⟨10.1016/j.celrep.2019.05.109⟩
Journal articles hal-02180268v1
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Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux

Shaoyi Zhang , Yan Wang , Wei Xie , Ethan Howe , Nathalie Busschaert
Cell Death and Disease, 2019, 10 (3), pp.242. ⟨10.1038/s41419-019-1474-8⟩
Journal articles hal-02095603v1
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Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

Lawrence A Donehower , Thierry Soussi , Anil Korkut , Yuexin Liu , Andre Schultz
Cell Reports, 2019, 28 (5), pp.1370-1384.e5. ⟨10.1016/j.celrep.2019.07.001⟩
Journal articles hal-02281902v1
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Seshat: A Web service for accurate annotation, validation, and analysis of TP53 variants generated by conventional and next-generation sequencing

Tuomas Tikkanen , Bernard Leroy , Jean Louis Fournier , Rosa Ana Risques , Jitka Malcikova
Human Mutation, 2018, 39 (7), pp.925-933. ⟨10.1002/humu.23543⟩
Journal articles hal-02318087v1
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Emergence and evolution of TP53 mutations are a key feature of disease progression in myelodysplastic patients with lower-risk del(5q) treated with lenalidomide.

Laurence Lodé , Audrey Ménard , Laurent Flet , Steven Richebourg , Marion Loirat
Haematologica, 2018, Epub ahead of print. ⟨10.3324/haematol.2017.181404⟩
Journal articles inserm-01691580v1

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Bernard Leroy , Mandy L Ballinger , Fanny Baran-Marszak , Gareth L Bond , Antony Braithwaite
Cancer Research, 2017, 77 (6), pp.1250-1260. ⟨10.1158/0008-5472.CAN-16-2179⟩
Journal articles hal-02343459v1

TP53 mutations are early events in chronic lymphocytic leukemia disease progression and precede evolution to complex karyotypes

Gregory Lazarian , Eugen Tausch , Virginie Eclache , Amel Sebaa , Vincent Bianchi
International Journal of Cancer, 2016, 139 (8), pp.1759-1763. ⟨10.1002/ijc.30222⟩
Journal articles hal-02060820v1
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Genetic profiling of CLL: a ‘TP53 addict’ perspective

L Lodé , F Cymbalista , Thierry Soussi
Cell Death and Disease, 2016, 7 (1), pp.e2042. ⟨10.1038/cddis.2015.415⟩
Journal articles hal-01332729v1
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TP53: an oncogene in disguise

T Soussi , K G Wiman
Cell Death and Differentiation, 2015, 22 (8), pp.1239-1249. ⟨10.1038/cdd.2015.53⟩
Journal articles hal-01188060v1
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The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis

Bernard Leroy , Jean Louis Fournier , Chikashi Ishioka , Paola Monti , Alberto Inga
Nucleic Acids Research, 2013, 41 (D1), pp.D962 - D969. ⟨10.1093/nar/gks1033⟩
Journal articles hal-01590745v1

Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors.

Karolina Edlund , Ola Larsson , Adam Ameur , Ignas Bunikis , Ulf Gyllensten
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (24), pp.9551-6
Journal articles hal-01188067v1

MUT-TP53 2.0: a novel versatile matrix for statistical analysis of TP53 mutations in human cancera

Thierry Soussi , Dalil Hamroun , Linn Hjortsberg , Jean Michel Rubio-Nevado , Jean Louis Fournier
Human Mutation, 2010, 31 (9), pp.1020 - 1025. ⟨10.1002/humu.21313⟩
Journal articles hal-01681836v1

Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations.

Thierry Soussi , Shunsuke Kato , Pierre P Levy , Chikashi Ishioka
Human Mutation, 2005, 25 (1), pp.6-17. ⟨10.1002/humu.20114⟩
Journal articles hal-00597640v1
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UMD (Universal Mutation Database): 2005 update

Christophe Béroud , Dalil Hamroun , Gwenaelle Collod-Beroud , Catherine Boileau , Thierry Soussi
Human Mutation, 2005, 26 (3), pp.184 - 191. ⟨10.1002/humu.20210⟩
Journal articles hal-01669907v1

Versatile analysis of multiple macromolecular interactions by SPR imaging: application to p53 and DNA interaction

Emmanuel Maillart , Karen Brengel-Pesce , Delphine Capela , André Roget , Thierry Livache
Oncogene, 2004, 23, pp.5543-5550
Journal articles hal-00664871v1
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UMD (Universal mutation database): a generic software to build and analyze locus-specific databases.

Christophe Béroud , Gwenaëlle Collod-Béroud , Catherine Boileau , Thierry Soussi , Claudine Junien
Journal articles inserm-00143606v1
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Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint

Yannick Saintigny , Danielle Rouillard , Brigitte Chaput , Thierry Soussi , Bernard Lopez
Oncogene, 1999, 18, pp.3553-3663
Journal articles cea-01938157v1

Anti-apoptotic activity of p53 maps to the COOH-terminal domain and is retained in a highly oncogenic natural mutant

Patrice Lassus , Christelle Bertrand , Olivier Zugasti , Jean-Philippe Chambon , Thierry Soussi
Oncogene, 1999, 18 (33), pp.4699-4709. ⟨10.1038/sj.onc.1202841⟩
Journal articles hal-03101969v1

p53 antibodies in the saliva of patients with squamous cell carcinoma of the oral cavity

Mahvash Tavassoli , Nadège Brunel , Rehana Maher , Newell Johnson , Thierry Soussi
International Journal of Cancer, 1998, 78 (3), pp.390-391. ⟨10.1002/(SICI)1097-0215(19981029)78:3<390::AID-IJC23>3.0.CO;2-9⟩
Journal articles hal-02485485v1
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Software and database for the analysis of mutations in the human FBN1 gene

Gwenaelle Collod , Christophe Béroud , Thierry Soussi , Claudine Junien , Catherine Boileau
Nucleic Acids Research, 1996, 24 (1), pp.137-140. ⟨10.1093/nar/24.1.137⟩
Journal articles hal-01662876v1