Thomas Candela Maitre de conférences

Publications

Article dans une revue (21)

Spores of Clostridioides difficile are toxin delivery vehicles Carolina Cassona,Sara Ramalhete,Khira Amara,Thomas Candela,Imad Kansauet al. Communications Biology, 2024, 7 (1), pp.839. ⟨10.1038/s42003-024-06521-x⟩ Article dans une revue hal-04664956v1
A Streamlined Method to Obtain Biologically Active TcdA and TcdB Toxins from Clostridioides difficile Diane Sapa,Anaïs Brosse,Héloïse Coullon,Gauthier Péan de Ponfilly,Thomas Candelaet al. Toxins, 2024, 16 (1), pp 38. ⟨10.3390/toxins16010038⟩ Article dans une revue hal-04417180v1
The absence of surface D-alanylation, localized on lipoteichoic acid, impacts the Clostridioides difficile way of life and antibiotic resistance Pierre-Alexandre Lacotte,Sandrine Denis-Quanquin,Eva Chatonnat,Julie Le Bris,David Leparfaitet al. Frontiers in Microbiology, 2023, 14, ⟨10.3389/fmicb.2023.1267662⟩ Article dans une revue hal-04281897v1
Polysaccharide II Surface Anchoring, the Achilles’ Heel of Clostridioides difficile Jeanne Malet-Villemagne,Liang Yucheng,Laurent Evanno,Sandrine Denis-Quanquin,Jean-Emmanuel Hugonnetet al. Microbiology Spectrum, In press, ⟨10.1128/spectrum.04227-22⟩ Article dans une revue hal-04009559v1
Clostridioides difficile peptidoglycan modifications Héloïse Coullon,Thomas Candela Current Opinion in Microbiology, 2022, 65, pp.156-161. ⟨10.1016/j.mib.2021.11.010⟩ Article dans une revue hal-03933803v1
Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile Transito Garcia-Garcia,Sandrine Poncet,Elodie Cuenot,Thibaut Douché,Quentin Giai Gianettoet al. mBio, 2021, 12 (3), pp.e00519-21. ⟨10.1128/mBio.00519-21⟩ Article dans une revue pasteur-03243540v1
Human IgA binds a diverse array of commensal bacteria Delphine Sterlin,Jehane Fadlallah,Olivia Adams,Claire Fieschi,Christophe Parizotet al. Journal of Experimental Medicine, 2020, 217 (3), pp.e20181635. ⟨10.1084/jem.20181635⟩ Article dans une revue hal-02433421v1
Peptidoglycan analysis reveals that synergistic deacetylase activity in vegetative Clostridium difficile impacts the host response Héloïse Coullon,Aline Rifflet,Richard Wheeler,Claire Janoir,Ivo G Bonecaet al. Journal of Biological Chemistry, 2020, 295 (49), pp.16785-16796. ⟨10.1074/jbc.RA119.012442⟩ Article dans une revue hal-03332384v1
Correction: Human IgA bind a diverse array of commensal bacteria Delphine Sterlin,Jehane Fadlallah,Olivia Adams,Claire Fieschi,Christophe Parizotet al. Journal of Experimental Medicine, 2020, 217 (3), ⟨10.1084/jem.2018163501152020c⟩ Article dans une revue hal-03125222v1
AsnB is responsible for peptidoglycan precursor amidation in Clostridium difficile in the presence of vancomycin Fariza Ammam,Delphine Patin,Héloïse Coullon,Didier Blanot,Thierry Lambertet al. Microbiology, In press, 166 (6), ⟨10.1099/mic.0.000917⟩ Article dans une revue hal-02571416v1
CalY is a major virulence factor and a biofilm matrix protein Thomas Candela,Annette Fagerlund,Christophe Buisson,Nathalie Gilois,Anne‐brit Kolstøet al. Molecular Microbiology, 2019, 111 (6), pp.1416-1429. ⟨10.1111/mmi.14184⟩ Article dans une revue hal-02620254v2
The Ser/Thr kinase PrkC participates in cell wall homeostasis and antimicrobial resistance in Clostridium difficile Elodie Cuenot,Transito Garcia-Garcia,Thibaut Douche,Olivier Gorgette,Pascal Courtinet al. Infection and Immunity, 2019, 87 (8), pp.e00005-19. ⟨10.1128/IAI.00005-19⟩ Article dans une revue pasteur-02164685v1
Surfaceome and Proteosurfaceome in Parietal Monoderm Bacteria: Focus on Protein Cell-Surface Display Mickaël Desvaux,Thomas Candela,Pascale Serror Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.00100⟩ Article dans une revue hal-01727158v1
Clostridium difficile forms variable biofilms on abiotic surface Véronique Pantaleon,Marc Monot,Catherine Eckert,Sandra Hoys,Anne Collignonet al. Anaerobe, 2018, 53, pp.34-37. ⟨10.1016/j.anaerobe.2018.05.006⟩ Article dans une revue pasteur-02549240v1
N-Deacetylases required for muramic-δ-lactam production are involved in Clostridium difficile sporulation, germination, and heat resistance Héloïse Coullon,Aline Rifflet,Richard Wheeler,Claire Janoir,Ivo Gomperts Bonecaet al. Journal of Biological Chemistry, 2018, 293 (47), pp.18040-18054. ⟨10.1074/jbc.RA118.004273⟩ Article dans une revue hal-04374612v1
The &lt;em&gt;Clostridium difficile&lt;/em&gt; Protease Cwp84 Modulates both Biofilm Formation and Cell-Surface Properties Véronique Pantaleon,Anna Philibertine Soavelomandroso,Sylvie Bouttier,Romain Briandet,Bryan Roxaset al. PLoS ONE, 2015, 10 (4), ⟨10.1371/journal.pone.0124971⟩ Article dans une revue hal-02639033v1
N-acetylglucosamine deacetylases modulate the anchoring of the gamma-glutamyl capsule to the cell wall of Bacillus anthracis. Thomas Candela,Stavroula Balomenou,Willy Aucher,Vassilis Bouriotis,Jean-Pierre Simorreet al. Microbial Drug Resistance, 2014, 20 (3), pp.222-30. ⟨10.1089/mdr.2014.0063⟩ Article dans une revue hal-01119761v1
Encapsulated Bacillus anthracis interacts closely with liver endothelium. Alejandro Piris-Gimenez,Jean-Philippe Corre,Gregory Jouvion,Thomas Candela,Huot Khunet al. Journal of Infectious Diseases, 2009, 200 (9), pp.1381-9. ⟨10.1086/644506⟩ Article dans une revue pasteur-00512101v1
Edema toxin impairs anthracidal phospholipase A2 expression by alveolar macrophages. Benoît Raymond,Dominique Leduc,Lucas Ravaux,Ronan Le Goffic,Thomas Candelaet al. PLoS Pathogens, 2007, 3 (12), pp.e187. ⟨10.1371/journal.ppat.0030187⟩ Article dans une revue pasteur-00317899v1
Poly-gamma-glutamate in bacteria. Thomas Candela,Agnès Fouet Molecular Microbiology, 2006, 60 (5), pp.1091-8. ⟨10.1111/j.1365-2958.2006.05179.x⟩ Article dans une revue pasteur-00317429v1
CapE, a 47-amino-acid peptide, is necessary for Bacillus anthracis polyglutamate capsule synthesis. Thomas Candela,Michèle Mock,Agnès Fouet Journal of Bacteriology, 2005, 187 (22), pp.7765-72. ⟨10.1128/JB.187.22.7765-7772.2005⟩ Article dans une revue hal-00082806v1

Communication dans un congrès (5)

Le polysaccharide II est essentiel à la mise en place de la surface de C. difficile Jeanne Malet-Villemagne,Léa Huet,Claire Janoir,Isabelle Martin-Verstraete,Thomas Candela Bactéries sporulantes pathogènes ou d'intérêt technologique BSPIT, Nov 2023, Paris, France Communication dans un congrès hal-04341988v1
A new method to produce TcdA and TcdB toxins from Clostridioides difficile Afi Akofa Diane Sapa,Anaïs Brosse,Héloïse Coullon,Gauthier Péan de Ponfilly,Thomas Candelaet al. Réunion Réseau CD France #5, RCDF, Jun 2023, Paris Institut Pasteur, France Communication dans un congrès hal-04420506v1
La D-alanylation de la surface de Clostridioides difficile permet une résistance accrue aux antibiotiques Pierre-Alexandre Lacotte,Sandrine Denis‐quanquin,Isabelle Martin-Verstraete,Thomas Candela SFM, Oct 2022, Montpelier, France Communication dans un congrès hal-04341953v1
Altered spore cortex impairs virulence in &lt;i&gt;C. difficile&lt;/i&gt; Héloïse Coullon,Aline Rifflet,Richard Wheeler,Claire Janoir,Ivo Bonecaet al. Bactéries Sporulantes Pathogènes ou d'Intérêt Technologique, INRAE, Mar 2018, Paris, France Communication dans un congrès hal-04341916v1
Muramic-δ-lactams are involved in &lt;i&gt;C. difficile&lt;/i&gt; sporulation, germination and virulence Héloïse Coullon,Aline Rifflet,Richard Wheeler,Claire Janoir,Ivo Bonecaet al. International Clostridium difficile Symposium, Sep 2018, Bled, Slovenia Communication dans un congrès hal-04341951v1

Poster de conférence (8)

Implementation of a high-throughput pipeline to identify antibiofilm molecules targeting mature biofilms of Staphylococcus aureus and Pseudomonas aeruginosa Onelia Bernabeu,Tania Kamwouo,Thomas Candela,Matttéo Gérard,Rut Carballido-Lópezet al. Antibiodeal Day, Mar 2026, Rennes, France Poster de conférence hal-05572530v1
A new method for the production of TcdA and TcdB toxins from Clostridioides difficile Afi Akofa Diane Sapa,Anaïs Brosse,Héloïse Coullon,Gauthier Péan de Ponfilly,Thomas Candelaet al. Clostpath 2023, Sep 2023, Banff, Canada Poster de conférence hal-04342523v1
The anchoring of the polysaccharide II is essential for Clostridioides difficile survival Jeanne Malet-Villemagne,Laurent Evanno,Sandrine Denis-Quanquin,Claire Janoir,Thomas Candela Clostpath 13, Sep 2023, Banff (Alberta), France Poster de conférence hal-04342006v1
The absence of surface D-alanylation, localized on lipoteichoic acid, impacts the Clostridioides difficile way of life and antibiotic resistance Pierre-Alexandre Lacotte,Sandrine Denis-Quanquin,Isabelle Martin-Verstraete,Thomas Candela Clostpath 13, Sep 2023, Banff (Alberta), France Poster de conférence hal-04342019v1
A new method for the production of TcdA and TcdB toxins from Clostridioides difficile Alban Le Monnier,Afi Akofa Diane Sapa,Anaïs Brosse,Gauthier Péan de Ponfilly,Thomas Candela ECCMID, Apr 2023, Copenhage, Denmark Poster de conférence hal-04336412v1
Nouvelle méthode de production des toxines TcdA et TcdB de C. difficile Afi Akofa Diane Sapa,Anaïs Brosse,Jeanne Malet-Villemagne,Gauthier Péan de Ponfilly,Thomas Candelaet al. MICROBES, Oct 2022, Montpellier, France Poster de conférence hal-04336498v1
Nouvelle méthode de production des toxines TcdA et TcdB de Clostridioides difficile Afi Akofa Diane Sapa,Anaïs Brosse,Jeanne Malet-Villemagne,Gauthier Pean De Ponfilly,Alban Le Monnieret al. Microbes 2022, Oct 2022, Montpellier, France Poster de conférence hal-04336544v1
The anchoring of the polysaccharide II is essential for Clostridioides difficile survival Jeanne Malet-Villemagne,Laurent Evanno,Sandrine Denis‐quanquin,Claire Janoir,Thomas Candela Anaerobe, Jul 2022, Seatle, France Poster de conférence hal-04341931v1