Timothée Bruel

Identifiants chercheurs

IdHAL :

timothee-bruel

ORCID :

0000-0002-3952-4261

IdRef :

169340171

Présentation

Publications

Article dans une revue (87)

Impaired serum neutralization and death in Omicron-infected critically ill patients: insights from the French SEVARVIR prospective, multicenter cohort study Timothée Bruel,Isabelle Staropoli,Pierre Bay,Paul Bastard,Sébastien Préauet al. Intensive Care Medicine Experimental, 2025, 13 (1), pp.121. ⟨10.1186/s40635-025-00831-y⟩ Article dans une revue hal-05402621v1
Impaired serum neutralization and death in Omicron-infected critically ill patients: insights from the French SEVARVIR prospective, multicenter cohort study Timothée Bruel,Isabelle Staropoli,Pierre Bay,Paul Bastard,Sébastien Préauet al. Intensive Care Medicine Experimental, 2025, 13 (1), pp.121. ⟨10.1186/s40635-025-00831-y⟩ Article dans une revue hal-05500222v1
Multiplex ACE2-RBD binding inhibition assay: An integrated tool for assessing neutralizing antibodies to SARS-CoV-2 variants and protection against breakthrough infections Emma Bloch,Laura Garcia,Françoise Donnadieu,Jason Rosado,Delphine Planaset al. Journal of Immunological Methods, 2025, 541, pp.113886. ⟨10.1016/j.jim.2025.113886⟩ Article dans une revue pasteur-05266592v1
BA.1 breakthrough infection elicits distinct antibody and memory B cell responses in vaccinated-only versus hybrid immunity individuals Carla Saade,Timothée Bruel,Lou-Léna Vrignaud,Martin Killian,Annabelle Drouillardet al. iScience, 2025, 28 (4), pp.111962. ⟨10.1016/j.isci.2025.111962⟩ Article dans une revue hal-04941427v1
Viral clearance and escape during therapy of COVID-19 outpatients: A prospective cohort study Guillaume Martin-Blondel,Paul Burgat,Valentin Leducq,Françoise Porrot,Andrea Cottignies-Calamarteet al. iScience, 2025, 28 (12), pp.114226. ⟨10.1016/j.isci.2025.114226⟩ Article dans une revue inserm-05509788v1
Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2 Cyril Planchais,Ignacio Fernández,Benjamin Chalopin,Timothée Bruel,Pierre Rosenbaumet al. iScience, 2024, 27 (7), pp.110354. ⟨10.1016/j.isci.2024.110354⟩ Article dans une revue pasteur-04645014v1
Beta-variant recombinant booster vaccine elicits broad cross-reactive neutralization of SARS-CoV-2 including Omicron variants Delphine Planas,Lin Peng,Lingyi Zheng,Florence Guivel-Benhassine,Isabelle Staropoliet al. Heliyon, 2024, 10 (5), pp.e27033. ⟨10.1016/j.heliyon.2024.e27033⟩ Article dans une revue pasteur-04767306v1
In Vitro and In Vivo Neutralizing Efficacy of Monoclonal Antibodies Against Sars-Cov-2 Variants in Kidney Transplant Recipients Ilies Benotmane,Martin Jungbauer-Groznica,Isabelle Staropoli,Delphine Planas,Océane Dehanet al. Transplant International, 2024, 37, pp.13272. ⟨10.3389/ti.2024.13272⟩ Article dans une revue pasteur-04767314v1
Sex- and species-associated differences in complement-mediated immunity in humans and rhesus macaques Natasha S Kelkar,Benjamin S Goldberg,Jérémy Dufloo,Timothée Bruel,Olivier Schwartzet al. mBio, 2024, 15 (3), pp.e0028224. ⟨10.1128/mbio.00282-24⟩ Article dans une revue pasteur-04767329v1
Levels and functionality of Pacific Islanders’ hybrid humoral immune response to BNT162b2 vaccination and delta/omicron infection: A cohort study in New Caledonia Catherine Inizan,Adrien Courtot,Chloé Sturmach,Anne-Fleur Griffon,Antoine Bironet al. PLoS Medicine, 2024, 21 (9), pp.e1004397. ⟨10.1371/journal.pmed.1004397⟩ Article dans une revue pasteur-04767341v1
High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1 William Bolland,Vincent Michel,Delphine Planas,Mathieu Hubert,Isabelle Staropoliet al. Journal of Virology, 2024, 98 (1), pp.e0135123. ⟨10.1128/jvi.01351-23⟩ Article dans une revue pasteur-04369613v1
Synthesis and Evaluation of 9-Aminoacridines with SARS-CoV-2 Antiviral Activity Thane Jones,Natalia Monakhova,Florence Guivel-Benhassine,Alexander Lepioshkin,Timothée Bruelet al. ACS Omega, 2023, 8 (43), pp.40817 - 40822. ⟨10.1021/acsomega.3c05900⟩ Article dans une revue pasteur-04767321v1
Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies Delphine Planas,Timothée Bruel,Isabelle Staropoli,Florence Guivel-Benhassine,Françoise Porrotet al. Nature Communications, 2023, 14 (1), pp.824. ⟨10.1038/s41467-023-36561-6⟩ Article dans une revue hal-04087563v2
Complement contributes to antibody-mediated protection against repeated SHIV challenge Benjamin Goldberg,David Spencer,Shilpi Pandey,Tracy Ordonez,Philip Barnetteet al. Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (20), pp.e2221247120. ⟨10.1073/pnas.2221247120⟩ Article dans une revue pasteur-04165265v1
Polyfunctionality of broadly neutralizing HIV-1 antibodies Lou-Léna Vrignaud,Olivier Schwartz,Timothée Bruel Current Opinion in HIV and AIDS, 2023, 18 (4), pp.178-183. ⟨10.1097/COH.0000000000000799⟩ Article dans une revue pasteur-04138728v1
Estimated protection against COVID-19 based on predicted neutralisation titres from multiple antibody measurements in a longitudinal cohort, France, April 2020 to November 2021 Tom Woudenberg,Laurie Pinaud,Laura Garcia,Laura Tondeur,Stephane Pelleauet al. Eurosurveillance, 2023, 28 (25), ⟨10.2807/1560-7917.ES.2023.28.25.2200681⟩ Article dans une revue hal-04146212v1
Modeling the evolution of the neutralizing antibody response against SARS-CoV-2 variants after several administrations of Bnt162b2 Quentin Clairon,Mélanie Prague,Delphine Planas,Timothée Bruel,Laurent Hocquelouxet al. PLoS Computational Biology, 2023, 19 (8), pp.e1011282. ⟨10.1371/journal.pcbi.1011282⟩ Article dans une revue hal-03946556v1
Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals Mathieu Hubert,Florence Guivel-Benhassine,Timothée Bruel,Françoise Porrot,Delphine Planaset al. Cell Host & Microbe, 2023, 31 (6), pp.937-948.e4. ⟨10.1016/j.chom.2023.05.001⟩ Article dans une revue hal-04309033v1
Sotrovimab therapy elicits antiviral activities against Omicron BQ.1.1 and XBB.1.5 in sera of immunocompromised patients [letter] Timothée Bruel,Lou-Léna Vrignaud,Françoise Porrot,Isabelle Staropoli,Delphine Planaset al. Med, 2023, 4 (10), pp.664-667. ⟨10.1016/j.medj.2023.07.007⟩ Article dans une revue pasteur-04369632v1
Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis David Spencer,Benjamin Goldberg,Shilpi Pandey,Tracy Ordonez,Jérémy Duflooet al. Nature Communications, 2022, 13 (1), pp.662. ⟨10.1038/s41467-022-28250-7⟩ Article dans une revue pasteur-03696775v1
Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based, prospective, longitudinal cohort study Timothée Bruel,Laurie Pinaud,Laura Tondeur,Delphine Planas,Isabelle Staropoliet al. EClinicalMedicine, 2022, 51, pp.101576. ⟨10.1016/j.eclinm.2022.101576⟩ Article dans une revue hal-03740505v1
Case Report: Evolution of Humoral and Cellular Immunity in Two COVID-19 Breakthrough Infections After BNT162b2 Vaccine Floriane Gallais,Pierre Gantner,Delphine Planas,Morgane Solis,Timothée Bruelet al. Frontiers in Immunology, 2022, 13, pp.790212. ⟨10.3389/fimmu.2022.790212⟩ Article dans une revue pasteur-03696752v1
Duration of BA.5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infection Delphine Planas,Isabelle Staropoli,Françoise Porot,Florence Guivel-Benhassine,Lynda Handalaet al. Med, 2022, 3 (12), pp.838-847.e3. ⟨10.1016/j.medj.2022.09.010⟩ Article dans une revue pasteur-04082610v1
COVID-19 outbreak in vaccinated patients from a haemodialysis unit: antibody titres as a marker of protection from infection Idris Boudhabhay,Alexandra Serris,Aude Servais,Delphine Planas,Aurélie Hummelet al. Nephrology Dialysis Transplantation, 2022, pp.gfac016. ⟨10.1093/ndt/gfac016⟩ Article dans une revue pasteur-03696758v1
IRF8 regulates efficacy of therapeutic anti‐CD20 monoclonal antibodies Ludivine Grzelak,Ferdinand Roesch,Amaury Vaysse,Anne Biton,Rachel Legendreet al. European Journal of Immunology, 2022, 52 (10), pp.1648-1661. ⟨10.1002/eji.202250037⟩ Article dans une revue hal-03833626v1
Immunogenicity of BNT162b2 vaccine against the Alpha and Delta variants in immunocompromised patients with systemic inflammatory diseases Jerome Hadjadj,Delphine Planas,Amani Ouedrani,Solene Buffier,Laure Delageet al. Annals of the Rheumatic Diseases, 2022, 81 (5), pp.720-728. ⟨10.1136/annrheumdis-2021-221508⟩ Article dans une revue hal-03698561v1
Considerable escape of SARS-CoV-2 Omicron to antibody neutralization Delphine Planas,Nell Saunders,Piet Maes,Florence Guivel-Benhassine,Cyril Planchaiset al. Nature, 2022, 602 (7898), pp.671-675. ⟨10.1038/s41586-021-04389-z⟩ Article dans une revue pasteur-03654259v1
A fourth dose of the mRNA-1273 SARS-CoV-2 vaccine improves serum neutralization against the Delta variant in kidney transplant recipients Ilies Benotmane,Timothée Bruel,Delphine Planas,Samira Fafi-Kremer,Olivier Schwartzet al. Kidney International, 2022, 101 (5), pp.1073-1076. ⟨10.1016/j.kint.2022.02.011⟩ Article dans une revue pasteur-03696743v1
Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2 Nell Saunders,Delphine Planas,William Bolland,Christophe Rodriguez,Slim Fouratiet al. EBioMedicine, 2022, 77, pp.103934. ⟨10.1016/j.ebiom.2022.103934⟩ Article dans une revue pasteur-03654246v1
Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies Olivier Schwartz,Thierry Prazuck,Benjamin Terrier,Emmanuel André,Etienne Simon-Loriereet al. Nature Medicine, 2022, ⟨10.1038/s41591-022-01792-5⟩ Article dans une revue pasteur-03654237v1
Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen Alice Mac Kain,Ghizlane Maarifi,Sophie-Marie Aicher,Nathalie Arhel,Artem Baidaliuket al. Nature Communications, 2022, 13, 13 p. ⟨10.1038/s41467-022-30134-9⟩ Article dans une revue pasteur-03707111v2
Robust and Functional Immune Memory Up to 9 Months After SARS-CoV-2 Infection: A Southeast Asian Longitudinal Cohort Hoa Thi My Vo,Alvino Maestri,Heidi Auerswald,Sopheak Sorn,Sokchea Layet al. Frontiers in Immunology, 2022, 13, pp.817905. ⟨10.3389/fimmu.2022.817905⟩ Article dans une revue pasteur-03654271v1
Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells Jérémy Dufloo,Cyril Planchais,Stéphane Frémont,Valerie Lorin,Florence Guivel-Benhassineet al. Nature Communications, 2022, 13 (1), pp.630. ⟨10.1038/s41467-022-28307-7⟩ Article dans une revue pasteur-03654220v1
Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody Jonathan Torres,Gabriel Ozorowski,Emanuele Andreano,Hejun Liu,Jeffrey Coppset al. Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (20), pp.e2120976119. ⟨10.1073/pnas.2120976119⟩ Article dans une revue pasteur-04082754v1
Kinetics of the SARS-CoV-2 Antibody Avidity Response Following Infection and Vaccination Laura Garcia,Tom Woudenberg,Jason Rosado,Adam Dyer,Françoise Donnadieuet al. Viruses, 2022, Special Issue SARS-CoV-2 Research in France, 14 (7), pp.1491. ⟨10.3390/v14071491⟩ Article dans une revue pasteur-04082742v1
Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies Timothée Bruel,Karl Stéfic,Yann Nguyen,Donatella Toniutti,Isabelle Staropoliet al. Cell Reports Medicine, 2022, 3 (12), pp.100850. ⟨10.1016/j.xcrm.2022.100850⟩ Article dans une revue pasteur-04165260v1
Potent human broadly SARS-CoV-2–neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2 Cyril Planchais,Ignacio Fernández,Timothée Bruel,Guilherme Dias de Melo,Matthieu Protet al. Journal of Experimental Medicine, 2022, 219 (7), pp.e20220638. ⟨10.1084/jem.20220638⟩ Article dans une revue hal-03697587v1
Anti-CD38 therapy impairs SARS-CoV-2 vaccine response against alpha and delta variants in patients with multiple myeloma Soledad Henriquez,Jérémie Zerbit,Timothée Bruel,Amani Ouedrani,Delphine Planaset al. Blood, 2022, 139 (6), pp.942-946. ⟨10.1182/blood.2021013714⟩ Article dans une revue pasteur-03696807v1
Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity Benjamin S. Goldberg,Chengzi I. Kaku,Jérémy Dufloo,Timothée Bruel,Olivier Schwartzet al. mBio, 2021, 12 (5), pp.e01743-21. ⟨10.1128/mBio.01743-21⟩ Article dans une revue pasteur-03696816v1
Characteristics Associated with Olfactory and Taste Disorders in COVID-19 Simon Galmiche,Timothée Bruel,Yoann Madec,Laura Tondeur,Ludivine Grzelaket al. Neuroepidemiology, 2021, 55 (5), pp.381-386. ⟨10.1159/000517066⟩ Article dans une revue hal-03528578v1
Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques Romain Marlin,Veronique Godot,Sylvain Cardinaud,Mathilde Galhaut,Severin Coleonet al. Nature Communications, 2021, 12, pp.5215. ⟨10.1038/s41467-021-25382-0⟩ Article dans une revue hal-03481526v1
Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study Blandine Monel,Delphine Planas,Ludivine Grzelak,Nikaïa Smith,Nicolas Robillardet al. EBioMedicine, 2021, 73, pp.103637. ⟨10.1016/j.ebiom.2021.103637⟩ Article dans une revue hal-03408666v1
Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies Jérémy Dufloo,Ludivine Grzelak,Isabelle Staropoli,Yoann Madec,Laura Tondeuret al. Cell Reports Medicine, 2021, 2 (5), pp.100275. ⟨10.1016/j.xcrm.2021.100275⟩ Article dans une revue pasteur-03229805v1
SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance Rémy Robinot,Mathieu Hubert,Guilherme Dias de Melo,Françoise Lazarini,Timothée Bruelet al. Nature Communications, 2021, 12 (1), pp.4354. ⟨10.1038/s41467-021-24521-x⟩ Article dans une revue pasteur-03319522v1
SARS-CoV-2 infection in schools in a northern French city: a retrospective serological cohort study in an area of high transmission, France, January to April 2020 Arnaud Fontanet,Laura Tondeur,Rebecca Grant,Sarah Temmam,Yoann Madecet al. Eurosurveillance, 2021, 26 (15), pp.2001695. ⟨10.2807/1560-7917.es.2021.26.15.2001695⟩ Article dans une revue pasteur-03236257v1
Kinetics of the Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Response and Serological Estimation of Time Since Infection Stéphane Pelleau,Tom Woudenberg,Jason Rosado,Françoise Donnadieu,Laura Garciaet al. Journal of Infectious Diseases, 2021, 224 (9), pp.1489-1499. ⟨10.1093/infdis/jiab375⟩ Article dans une revue pasteur-03319587v2
Multiplex assays for the identification of serological signatures of SARS-CoV-2 infection: an antibody-based diagnostic and machine learning study Jason Rosado,Stéphane Pelleau,Charlotte A. Cockram,Sarah Hélène Merkling,Narimane Nekkabet al. The Lancet Microbe, 2021, 2 (2), pp.e60-e69. ⟨10.1016/S2666-5247(20)30197-X⟩ Article dans une revue hal-03128905v1
Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection Nader Yatim,Jeremy Boussier,Pauline Tetu,Nikaïa Smith,Timothée Bruelet al. Science Advances , 2021, 7 (34), pp.eabg4081. ⟨10.1126/sciadv.abg4081⟩ Article dans une revue pasteur-03334080v1
Sex Differences in the Evolution of Neutralizing Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2 Ludivine Grzelak,Auréie Velay-Rusch,Yoann Madec,Floriane Gallais,Isabelle Staropoliet al. Journal of Infectious Diseases, 2021, 224 (6), pp.983-988. ⟨10.1093/infdis/jiab127⟩ Article dans une revue hal-03606632v1
Sensitivity of infectious SARS-CoV-2 B.1.1.7 and B.1.351 variants to neutralizing antibodies Delphine Planas,Timothée Bruel,Ludivine Grzelak,Florence Guivel-Benhassine,Isabelle Staropoliet al. Nature Medicine, 2021, ⟨10.1038/s41591-021-01318-5⟩ Article dans une revue pasteur-03207907v1
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization Delphine Planas,David Veyer,Artem Baidaliuk,Isabelle Staropoli,Florence Guivel-Benhassineet al. Nature, 2021, 596 (7871), pp.276-280. ⟨10.1038/s41586-021-03777-9⟩ Article dans une revue pasteur-03696844v1
Sera neutralizing activities against SARS-CoV-2 and multiple variants six month after hospitalization for COVID-19 Maureen Betton,Marine Livrozet,Delphine Planas,Antoine Fayol,Blandine Monelet al. Clinical Infectious Diseases, 2021, pp.ciab308. ⟨10.1093/cid/ciab308⟩ Article dans une revue pasteur-03229817v1
Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection Nikaïa Smith,Pedro Goncalves,Bruno Charbit,Ludivine Grzelak,Maxime Berettaet al. Nature Immunology, 2021, ⟨10.1038/s41590-021-01028-7⟩ Article dans une revue pasteur-03384279v1
Transmission of SARS-CoV-2 Alpha Variant (B.1.1.7) From a BNT162b2-Vaccinated Individual Solen Kernéis,Delphine Planas,Sandrine Imbeaud,Isabelle Staropoli,Julien Puechet al. Open Forum Infectious Diseases, 2021, 8 (8), pp.ofab369. ⟨10.1093/ofid/ofab369⟩ Article dans une revue pasteur-03696825v1
Author Correction: Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers Stéphane Marot,Isabelle Malet,Valentin Leducq,Karen Zafilaza,Delphine Sterlinet al. Nature Communications, 2021, 12 (1), pp.2824. ⟨10.1038/s41467-021-23128-6⟩ Article dans une revue hal-03997295v1
Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers Stéphane Marot,Isabelle Malet,Valentin Leducq,Karen Zafilaza,Delphine Sterlinet al. Nature Communications, 2021, 12 (1), pp.844. ⟨10.1038/s41467-021-21111-9⟩ Article dans une revue hal-03138467v1
Evolution of antibody responses up to 13 months after SARS-CoV-2 infection and risk of reinfection Floriane Gallais,Pierre Gantner,Timothée Bruel,Aurélie Velay,Delphine Planaset al. EBioMedicine, 2021, 71, pp.103561. ⟨10.1016/j.ebiom.2021.103561⟩ Article dans une revue hal-03500711v1
IgA dominates the early neutralizing antibody response to SARS-CoV-2 Delphine Sterlin,Alexis Mathian,Makoto Miyara,Audrey Mohr,François Annaet al. Science Translational Medicine, 2020, pp.eabd2223. ⟨10.1126/scitranslmed.abd2223⟩ Article dans une revue hal-03105620v1
Flow Cytometry Analysis of HIV-1 Env Conformations at the Surface of Infected Cells and Virions: Role of Nef, CD4, and SERINC5 Isabelle Staropoli,Jérémy Dufloo,Anaïs Ducher,Pierre-Henri Commère,Anna Sartori-Ruppet al. Journal of Virology, 2020, 94 (6), ⟨10.1128/JVI.01783-19⟩ Article dans une revue pasteur-02561978v1
Serologic responses to SARS-CoV-2 infection among hospital staff with mild disease in eastern France Samira Fafi-Kremer,Timothée Bruel,Yoann Madec,Rebecca Grant,Laura Tondeuret al. EBioMedicine, 2020, 59, pp.102915. ⟨10.1016/j.ebiom.2020.102915⟩ Article dans une revue hal-03606631v1
A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations Ludivine Grzelak,Sarah Temmam,Cyril Planchais,Caroline Demeret,Laura Tondeuret al. Science Translational Medicine, 2020, 12 (559), pp.eabc3103. ⟨10.1126/scitranslmed.abc3103⟩ Article dans une revue pasteur-03139185v1
Syncytia formation by SARS‐CoV‐2‐infected cells Julian Buchrieser,Jérémy Dufloo,Mathieu Hubert,Blandine Monel,Delphine Planaset al. EMBO Journal, 2020, 39 (23), pp.e106267. ⟨10.15252/embj.2020106267⟩ Article dans une revue pasteur-03253133v1
Accelerated thymopoiesis and improved T‐cell responses in HLA‐A2/‐DR2 transgenic BRGS‐based human immune system mice Guillemette Masse-Ranson,Mathilde Dusseaux,Oriane Fiquet,Sylvie Darche,Maud Boussandet al. European Journal of Immunology, 2019, 49 (6), pp.954-965. ⟨10.1002/eji.201848001⟩ Article dans une revue pasteur-02875581v1
HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells Cyril Planchais,Ayrin Kök,Alexia Kanyavuz,Valérie Lorin,Timothée Bruelet al. Cell Reports, 2019, 27 (2), pp.572-585.e7. ⟨10.1016/j.celrep.2019.03.032⟩ Article dans une revue hal-02102470v1
Anti‐ HIV ‐1 antibodies trigger non‐lytic complement deposition on infected cells Jérémy Dufloo,Florence Guivel-Benhassine,Julian Buchrieser,Valérie Lorin,Ludivine Grzelaket al. EMBO Reports, 2019, 21 (2), pp.e49351. ⟨10.15252/embr.201949351⟩ Article dans une revue pasteur-03239697v1
Structural Basis for Broad HIV-1 Neutralization by a Novel MPER-Specific Human Broadly Neutralizing Antibody Dora Pinto,Craig Fenwick,Christophe Caillat,Chiara Silacci,Serafima Gusevaet al. Cell Host and Microbe, 2019, 26 (5), pp.623-637.e8. ⟨10.2139/ssrn.3416843⟩ Article dans une revue hal-02336304v1
Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection Nadia Echebli,Nicolas Tchitchek,Stéphanie Dupuy,Timothée Bruel,Caroline Passaeset al. PLoS ONE, 2018, 13 (1), pp.e0190334. ⟨10.1371/journal.pone.0190334⟩ Article dans une revue hal-02861901v1
Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity Julie Prigent,Annaëlle Jarossay,Cyril Planchais,Caroline Eden,Jérémy Duflooet al. Cell Reports, 2018, 23 (9), pp.2568-2581. ⟨10.1016/j.celrep.2018.04.101⟩ Article dans une revue hal-01803507v1
A human immune system mouse model with robust lymph node development Yan Li,Guillemette Masse-Ranson,Zacarias Garcia,Timothée Bruel,Ayrin Köket al. Nature Methods, 2018, 15 (8), pp.623-630. ⟨10.1038/s41592-018-0071-6⟩ Article dans une revue pasteur-02875578v1
Zika virus induces massive cytoplasmic vacuolization and paraptosis‐like death in infected cells Blandine Monel,Alex Compton,Timothée Bruel,Sonia Amraoui,Julien Burlaud-Gaillardet al. EMBO Journal, 2017, 36 (12), pp.1653-1668. ⟨10.15252/embj.201695597⟩ Article dans une revue pasteur-03253584v1
Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents Caroline Pereira Bittencourt Passaes,Timothée Bruel,Jérémie Decalf,Annie David,Mathieu Anginet al. Journal of Virology, 2017, 91 (6), pp.e02296-16. ⟨10.1128/JVI.02296-16⟩ Article dans une revue pasteur-01484315v1
Lack of ADCC breadth of human non-neutralizing anti-HIV-1 antibodies. Timothée Bruel,Florence Guivel-Benhassine,Valérie Lorin,Hugues Lortat-Jacob,Françoise Baleuxet al. Journal of Virology, 2017, 91 (8), pp.e02440-16. ⟨10.1128/JVI.02440-16⟩ Article dans une revue hal-01487928v1
Corrigendum: CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses B Descours,G Petitjean,Jl López-Zaragoza,T Bruel,R Raffelet al. Nature, 2017, 546 (7660), pp.686. ⟨10.1038/nature22807⟩ Article dans une revue hal-01503531v1
HIV Fusion in Dendritic Cells Occurs Mainly at the Surface and Is Limited by Low CD4 Levels Lise Chauveau,Daniel Aaron Donahue,Blandine Monel,Francoise Porrot,Timothée Bruelet al. Journal of Virology, 2017, 91 (21), ⟨10.1128/JVI.01248-17⟩ Article dans une revue pasteur-03253577v1
CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses Benjamin Descours,Gaël Petitjean,José-Luis López-Zaragoza,Timothée Bruel,Raoul Raffelet al. Nature, 2017, 543 (7646), pp.564 - 567. ⟨10.1038/nature21710⟩ Article dans une revue hal-01777383v1
Broadly neutralizing antibodies suppress post-transcytosis HIV-1 infectivity Valérie Lorin,M Malbec,C Eden,T Bruel,F Porrotet al. Mucosal Immunology, 2016, ⟨10.1038/mi.2016.106⟩ Article dans une revue pasteur-01417469v1
CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge. Kevin K Ariën,Françoise Baleux,Delphine Desjardins,Françoise Porrot,Yves-Marie Coïcet al. Scientific Reports, 2016, 6, pp.34829. ⟨10.1038/srep34829⟩ Article dans une revue pasteur-01423094v1
Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles Chiraz Hamimi,Annie David,Pierre Versmisse,Laurence Weiss,Timothée Bruelet al. PLoS ONE, 2016, 11 (8), pp.e0160251. ⟨10.1371/journal.pone.0160251⟩ Article dans une revue hal-01375755v1
Elimination of HIV-1-infected cells by broadly neutralizing antibodies. Timothée Bruel,Florence Guivel-Benhassine,Sonia Amraoui,Marine Malbec,Léa Richardet al. Nature Communications, 2015, 7, pp.10844. ⟨10.1038/ncomms10844⟩ Article dans une revue pasteur-01372390v1
SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells. Diana Ayinde,Timothée Bruel,Sylvain Cardinaud,Françoise Porrot,Julia G Pradoet al. Journal of Virology, 2015, 89 (14), pp.6994-7006. ⟨10.1128/JVI.00069-15⟩ Article dans une revue pasteur-01372403v1
Long-Term Control of Simian Immunodeficiency Virus (SIV) in Cynomolgus Macaques Not Associated with Efficient SIV-Specific CD8 + T-Cell Responses. Timothée Bruel,Chiraz Hamimi,Nathalie Dereuddre-Bosquet,Antonio Cosma,So Youn Shinet al. Journal of Virology, 2015, 89 (7), pp.3542 - 3556. ⟨10.1128/JVI.03723-14⟩ Article dans une revue pasteur-01414959v1
IFITM Proteins Incorporated into HIV-1 Virions Impair Viral Fusion and Spread. Alex A Compton,Timothée Bruel,Françoise Porrot,Adeline Mallet,Martin Sachseet al. Cell Host and Microbe, 2014, 16 (6), pp.736-47. ⟨10.1016/j.chom.2014.11.001⟩ Article dans une revue pasteur-01109877v1
Plasmacytoid Dendritic Cell Dynamics Tune Interferon-Alfa Production in SIV-Infected Cynomolgus Macaques Timothée Bruel,Stéphanie Dupuy,Thomas Démoulins,Christine Rogez-Kreuz,Jacques Dutrieuxet al. PLoS Pathogens, 2014, 10 (1), pp.e1003915. ⟨10.1371/journal.ppat.1003915⟩ Article dans une revue hal-02940446v1
Porcine colon explants in the study of innate immune response to Entamoeba histolytica Fabienne Girard-Misguich,Mario Delgado-Ortega,Patricia Berthon,Christelle Rossignol,Thibaut T. Larcheret al. Veterinary Immunology and Immunopathology, 2012, 145 (3-4), pp.611-617. ⟨10.1016/j.vetimm.2012.01.002⟩ Article dans une revue istex hal-02650556v1
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Expression and immunogenicity of the mycobacterial Ag85B/ESAT-6 antigens produced in transgenic plants by elastin-like peptide fusion strategy. Doreen Manuela Floss,Michael Mockey,Galliano Zanello,Damien Brosson,Marie Diogonet al. Journal of Biomedicine and Biotechnology, 2010, 2010, pp.274346. ⟨10.1155/2010/274346⟩ Article dans une revue hal-00528178v1
Epithelial induction of porcine suppressor of cytokine signaling 2 (SOCS2) gene expression in response to Entamoeba histolytica Timothée Bruel,Roseline Guibon,Sandrina Melo,Nancy Guillén,Henri H. Salmonet al. Developmental and Comparative Immunology, 2010, 34 (5), pp.562-571. ⟨10.1016/j.dci.2009.12.017⟩ Article dans une revue istex hal-02665993v1

Communication dans un congrès (1)

Amibiase humaine : établissement d'un modèle porcin Francois Meurens,F Girard-Misguich,T Bruel,R Guibon,S Meloet al. Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu Communication dans un congrès hal-02818906v1

Pré-publication, Document de travail (6)

Serological reconstruction of COVID-19 epidemics through analysis of antibody kinetics to SARS-CoV-2 proteins Stéphane Pelleau,Tom Woudenberg,Jason Rosado,Françoise Donnadieu,Laura Garciaet al. 2021 Pré-publication, Document de travail pasteur-03161603v1
Distinct systemic and mucosal immune responses to SARS-CoV-2 Nikaïa Smith,Pedro Goncalves,Bruno Charbit,Ludivine Grzelak,Maxime Berettaet al. 2021 Pré-publication, Document de travail pasteur-03244398v1
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SARS-CoV-2 infection in primary schools in northern France: A retrospective cohort study in an area of high transmission Arnaud Fontanet,Rebecca Grant,Laura Tondeur,Yoann Madec,Ludivine Grzelaket al. 2021 Pré-publication, Document de travail pasteur-03147095v1
A simple, sensitive and quantitative FACS-based test for SARS-CoV-2 serology in humans and animals Agnès Maurel Ribes,Pierre Bessière,Jean Charles Guéry,Eloïse Joly Featherstone,Timothée Bruelet al. 2021 Pré-publication, Document de travail hal-03338518v2
Cluster of COVID-19 in northern France: A retrospective closed cohort study Arnaud Fontanet,Laura Tondeur,Yoann Madec,Rebecca Grant,Camille Besombeset al. 2021 Pré-publication, Document de travail pasteur-03147081v1