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Valérie Gabelica

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New 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinazoline and 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinoline derivatives: synthesis and biological evaluation as novel anticancer agents by targeting G-quadruplex

Jean Guillon , Marc Le Borgne , Vittoria Milano , Aurore Guédin-Beaurepaire , Stéphane Moreau
Pharmaceuticals, 2024, 17 (1), pp.30. ⟨10.3390/ph17010030⟩
Journal articles hal-04390485v1
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Native Electrospray Ionization of Multi-Domain Proteins via a Bead Ejection Mechanism

Nina Khristenko , Frédéric Rosu , Eric Largy , Jérôme Haustant , Cédric Mesmin
Journal of the American Chemical Society, 2023, 145 (1), pp.498 - 506. ⟨10.1021/jacs.2c10762⟩
Journal articles hal-04119433v1
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Thiosugar naphthalene diimide conjugates: G-quadruplex ligands with antiparasitic and anticancer activity

Efres Belmonte-Reche , Alessandra Benassi , Pablo Peñalver , Anne Cucchiarini , Aurore Guédin
European Journal of Medicinal Chemistry, 2022, 232, pp.114183. ⟨10.1016/j.ejmech.2022.114183⟩
Journal articles hal-03807361v1
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Adaptive Binding of Alkyl Glycosides by Nonpeptidic Helix Bundles in Water: Toward Artificial Glycolipid Binding Proteins

Sung Hyun Yoo , Jérémie Buratto , Arup Roy , Estelle Morvan , Morgane Pasco
Journal of the American Chemical Society, 2022, 144 (35), pp.15988-15998. ⟨10.1021/jacs.2c05234⟩
Journal articles hal-03862795v1
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Structural adaptations of electrosprayed aromatic oligoamide foldamers on Ag(111)

Dennis Meier , Benedikt Schoof , Jinhua Wang , Xuesong Li , Andreas Walz
Chemical Communications, 2022, 58 (64), pp.8938-8941. ⟨10.1039/D2CC03286D⟩
Journal articles hal-04275254v1
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Design, Synthesis, and Antiprotozoal Evaluation of New Promising 2,9-Bis[(substituted-aminomethyl)]-4,7-phenyl-1,10phenanthroline Derivatives, a Potential Alternative Scaffold to Drug Efflux

Jean Guillon , Anita Cohen , Clotilde Boudot , Sarah Monic , Solène Savrimoutou
Pathogens, 2022, 11 (11), pp.1339. ⟨10.3390/pathogens11111339⟩
Journal articles inserm-03850360v1
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Optimization of G‐Quadruplex Ligands through a SAR Study by Combining Parallel Synthesis and Screening of Cationic Bis(acylhydrazones)

Oksana Reznichenko , Denis Leclercq , Jaime Franco Pinto , Liliane Mouawad , Valérie Gabelica
Chemistry - A European Journal, 2022, ⟨10.1002/chem.202202427⟩
Journal articles hal-03837862v1
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Phen‐DC 3 Induces Refolding of Human Telomeric DNA into a Chair‐Type Antiparallel G‐Quadruplex through Ligand Intercalation

Anirban Ghosh , Marko Trajkovski , Marie‐paule Teulade-Fichou , Valérie Gabelica , Janez Plavec
Angewandte Chemie International Edition, 2022, 61 (40), pp.e202207384. ⟨10.1002/anie.202207384⟩
Journal articles hal-04119339v1
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Negative Electrospray Supercharging Mechanisms of Nucleic Acid Structures

Debasmita Ghosh , Frédéric Rosu , Valérie Gabelica
Analytical Chemistry, 2022, 94 (44), pp.15386-15394. ⟨10.1021/acs.analchem.2c03187⟩
Journal articles hal-04119279v1
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Native Mass Spectrometry and Nucleic Acid G-Quadruplex Biophysics: Advancing Hand in Hand

Valérie Gabelica
Accounts of Chemical Research, 2021, 54 (19), pp.3691-3699. ⟨10.1021/ACS.ACCOUNTS.1C00396⟩
Journal articles hal-03410850v1
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Quadruplex DNA-guided ligand selection from dynamic combinatorial libraries of acylhydrazones

Oksana Reznichenko , Anne Cucchiarini , Valérie Gabelica , Anton Granzhan
Organic & Biomolecular Chemistry, 2021, 19 (2), pp.379-386. ⟨10.1039/D0OB01908A⟩
Journal articles hal-03186431v1
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DNA G-quadruplexes for native mass spectrometry in potassium: a database of validated structures in electrospray-compatible conditions

Anirban Ghosh , Eric Largy , Valérie Gabelica
Nucleic Acids Research, 2021, 49 (4), pp.2333 - 2345. ⟨10.1093/nar/gkab039⟩
Journal articles hal-03321816v1
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Mass Spectrometry of Nucleic Acid Noncovalent Complexes

Eric Largy , Alexander König , Anirban Ghosh , Debasmita Ghosh , Sanae Benabou
Chemical Reviews, In press, ⟨10.1021/acs.chemrev.1c00386⟩
Journal articles hal-03410847v1

Unprecedented hour-long residence time of a cation in a left-handed G-quadruplex

Fernaldo Richtia Winnerdy , Blaž Bakalar , Poulomi Das , Brahim Heddi , Adrien Marchand
Chemical Science, 2021, 12 (20), pp.7151-7157. ⟨10.1039/d1sc00515d⟩
Journal articles hal-03321839v1
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A two-quartet G-quadruplex topology of human KIT2 is conformationally selected by a perylene derivative

Silvia Ceschi , Eric Largy , Valérie Gabelica , Claudia Sissi
Biochimie, 2020, 179, pp.77-84. ⟨10.1016/j.biochi.2020.09.015⟩
Journal articles hal-03321840v1

Effective Temperature and Structural Rearrangement in Trapped Ion Mobility Spectrometry

Denis Morsa , Emeline Hanozin , Gauthier Eppe , Loïc Quinton , Valérie Gabelica
Analytical Chemistry, 2020, 92 (6), pp.4573-4582. ⟨10.1021/acs.analchem.9b05850⟩
Journal articles hal-02882254v1
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Native Hydrogen/Deuterium Exchange Mass Spectrometry of Struc- tured DNA Oligonucleotides

Eric Largy , Valérie Gabelica
Analytical Chemistry, 2020, 92 (6), pp.4402-4410. ⟨10.1021/acs.analchem.9b05298⟩
Journal articles hal-02882153v1
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Computational strategies and challenges for using native ion mobility mass spectrometry in biophysics and structural biology

Timothy M. Allison , Perdita Barran , Sarah Cianférani , Matteo T. Degiacomi , Valérie Gabelica
Analytical Chemistry, 2020, 92 (16), pp.10872-10880. ⟨10.1021/acs.analchem.9b05791⟩
Journal articles hal-02960838v1
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Mass-resolved electronic circular dichroism ion spectroscopy

Steven Daly , Frederic Rosu , Valérie Gabelica
Science, 2020, 368 (6498), pp.1465-1468. ⟨10.1126/science.abb1822⟩
Journal articles hal-02882085v1
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Software requirements for the analysis and interpretation of native ion mobility mass spectrometry data

Timothy M. Allison , Perdita Barran , Justin L.P. Benesch , Sarah Cianférani , Mattéo T. Degiacomi
Analytical Chemistry, 2020, 92 (16), pp.10881-10890. ⟨10.1021/acs.analchem.9b05792⟩
Journal articles hal-02960834v1
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Collision Cross Sections of Phosphoric Acid Cluster Anions in Helium Measured by Drift Tube Ion Mobility Mass Spectrometry

Valentina Calabrese , Hélène Lavanant , Frédéric Rosu , Valérie Gabelica , Carlos Afonso
Journal of The American Society for Mass Spectrometry, 2020, 31 (4), pp.969-981. ⟨10.1021/jasms.0c00034⟩
Journal articles hal-02541705v1
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Compaction of RNA Hairpins and Their Kissing Complexes in Native Electrospray Mass Spectrometry

Josephine Abi-Ghanem , Clémence Rabin , Massimiliano Porrini , Frédéric Rosu , Valérie Gabelica
Journal of The American Society for Mass Spectrometry, 2020, 31 (10), pp.2035-2043. ⟨10.1021/jasms.0c00060⟩
Journal articles hal-03321844v1
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Native Ion Mobility Mass Spectrometry: When Gas-Phase Ion Structures Depend on the Electrospray Charging Process

Nina Khristenko , Jussara Amato , Sandrine Livet , Bruno Pagano , Antonio Randazzo
Journal of The American Society for Mass Spectrometry, 2019, 30 (6), pp.1069-1081. ⟨10.1007/s13361-019-02152-3⟩
Journal articles hal-02358221v1
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DNA and RNA telomeric G-quadruplexes: what topology features can be inferred from ion mobility mass spectrometry?

Valentina d'Atri , Valérie Gabelica
Analyst, 2019, 144 (20), pp.6074-6088. ⟨10.1039/C9AN01216H⟩
Journal articles hal-02358205v1
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Probing ligand and cation binding sites in G-quadruplex nucleic acids by mass spectrometry and electron photodetachment dissociation sequencing

Dababrata Paul , Adrien Marchand , Daniela Verga , Marie-Paule Teulade-Fichou , Sophie Bombard
Analyst, In press, ⟨10.1039/C9AN00398C⟩
Journal articles hal-02110949v1
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Recommendations for reporting ion mobility Mass Spectrometry measurements

Valérie Gabelica , Alexandre A Shvartsburg , Carlos Afonso , Perdita Barran , Justin L P Benesch
Mass Spectrometry Reviews, inPress, 38 (3), pp.291-320. ⟨10.1002/mas.21585⟩
Journal articles hal-02012317v1
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Fundamentals of ion mobility spectrometry

Valérie Gabelica , Erik Marklund
Current Opinion in Chemical Biology, 2018, 42, pp.51-59. ⟨10.1016/j.cbpa.2017.10.022⟩
Journal articles hal-01618661v3
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Thermal Denaturation of DNA G-Quadruplexes and Their Complexes with Ligands: Thermodynamic Analysis of the Multiple States Revealed by Mass Spectrometry

Adrien Marchand , Frederic Rosu , Renato Zenobi , Valérie Gabelica
Journal of the American Chemical Society, 2018, 140 (39), pp.12553-12565. ⟨10.1021/jacs.8b07302⟩
Journal articles hal-01910198v1
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More is not always better: finding the right trade-off between affinity and selectivity of a G-quadruplex ligand

Michela Zuffo , Aurore Guédin , Emma-Dune Leriche , Filippo Doria , Valentina Pirota
Nucleic Acids Research, In press, ⟨10.1093/nar/gky607⟩
Journal articles hal-01910129v1
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Parallel Guanine Duplex and Cytosine Duplex DNA with Uninterrupted Spines of Ag(I)-Mediated Base Pairs

Steven M Swasey , Frederic Rosu , Stacy M Copp , Valérie Gabelica , Elisabeth G Gwinn
Journal of Physical Chemistry Letters, 2018, 9 (22), pp.6605-6610. ⟨10.1021/acs.jpclett.8b02851⟩
Journal articles hal-02012389v1
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Influence of the Metals and Ligands in Dinuclear Complexes on Phosphopeptide Sequencing by Electron Transfer Dissociation Tandem Mass Spectrometry

Daiki Asakawa , Akio Miyazato , Frederic Rosu , Valérie Gabelica
Physical Chemistry Chemical Physics, 2018, 20, pp.26597-26607. ⟨10.1039/C8CP04516J⟩
Journal articles hal-01910173v1
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Electronic Spectroscopy of Isolated DNA Polyanions

Steven Daly , Massimiliano Porrini , Frederic Rosu , Valérie Gabelica
Faraday Discussions, 2018, Advances in ion spectroscopy - from astrophysics to biology, 217, pp.361-382. ⟨10.1039/C8FD00207J⟩
Journal articles hal-02012418v1
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Analysis of interaction between telomeric i-motif DNA and a cyclic tetraoxazole compound

Shadi Sedghi Masoud , Yudai Yamaoki , Yue Ma , Adrien Marchand , Fernando Richtia Winnerdy
ChemBioChem, 2018, 39 (21), pp.2268-2272. ⟨10.1002/cbic.201800425⟩
Journal articles hal-01910151v2
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Optimizing Native Ion Mobility Q-TOF in Helium and Nitrogen for Very Fragile Noncovalent Structures

Valérie Gabelica , Sandrine Livet , Frederic Rosu
Journal of The American Society for Mass Spectrometry, 2018, 29 (11), pp.2189-2198. ⟨10.1007/s13361-018-2029-4⟩
Journal articles hal-01910186v1
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Design, Synthesis, and Evaluation of 2,9-Bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline Derivatives as G-Quadruplex Ligands.

Nassima Meriem Gueddouda , Rosales Myanou Hurtado , Stéphane Moreau , Luisa Ronga , Rabindra Nath Das
ChemMedChem, 2017, 12 (2), pp.146-160. ⟨10.1002/cmdc.201600511⟩
Journal articles hal-01461586v1
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Compaction of Duplex Nucleic Acids upon Native Electrospray Mass Spectrometry

Massimiliano Porrini , Frédéric Rosu , Clémence Rabin , Leonardo Darré , Hansel Gómez
ACS Central Science, 2017, 3 (5), pp.454-461. ⟨10.1021/acscentsci.7b00084⟩
Journal articles hal-04127049v1
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Electrostatics Explains the Position-Dependent Effect of G⋅U Wobble Base Pairs on the Affinity of RNA Kissing Complexes

Josephine Abi‐ghanem , Clémence Rabin , Massimiliano Porrini , Eric Dausse , Jean‐jacques Toulmé
ChemPhysChem, 2017, 18 (19), pp.2782-2790. ⟨10.1002/cphc.201700337⟩
Journal articles hal-01629266v1
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Drift Tube Ion Mobility: How to Reconstruct Collision Cross Section Distributions from Arrival Time Distributions?

Adrien Marchand , Sandrine Livet , Frederic Rosu , Valérie Gabelica
Analytical Chemistry, 2017, ⟨10.1021/acs.analchem.7b01736⟩
Journal articles hal-01639191v1
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Specific Stabilization of c-MYC and c-KIT G-Quadruplex DNA Structures by Indolylmethyleneindanone Scaffolds

K V Diveshkumar , Saaz Sakrikar , Frédéric Rosu , S Harikrishna , Valérie Gabelica
Biochemistry, 2016, 55 (25), pp.3571-3585. ⟨10.1021/acs.biochem.6b00120⟩
Journal articles hal-01543404v1
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Selective and Cooperative Ligand Binding to Antiparallel Human Telomeric DNA G-Quadruplexes

Adrien Marchand , Dominika Strzelecka , Valérie Gabelica
Chemistry - A European Journal, 2016, 22 (28), pp.9551-9555. ⟨10.1002/chem.201601937⟩
Journal articles hal-01537094v1
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Folding and misfolding pathways of G-quadruplex DNA

Adrien Marchand , Valérie Gabelica
Nucleic Acids Research, 2016, ⟨10.1093/nar/gkw970⟩
Journal articles inserm-01385240v1
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Linking molecular models with ion mobility experiments. Illustration with a rigid nucleic acid structure

Valentina D 'Atri , Massimiliano Porrini , Frédéric Rosu , Valérie Gabelica
Journal of Mass Spectrometry, 2015, 50 (5), pp.711-726. ⟨10.1002/jms.3590⟩
Journal articles inserm-01146158v1
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Nucleic acid ion structures in the gas phase

Josephine Abi-Ghanem , Valérie Gabelica
Physical Chemistry Chemical Physics, 2014, 16 (39), pp.21204 - 21218. ⟨10.1039/C4CP02362E⟩
Journal articles inserm-01385789v1
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Distinctive structural motifs of RNA G-quadruplexes composed of AGG, CGG and UGG trinucleotide repeats

Magdalena Malgowska , Dorota Gudanis , Ryszard Kierzek , Eliza Wyszko , Valerie Gabelica
Nucleic Acids Research, 2014, 42 (15), pp.10196. ⟨10.1093/nar/gku710⟩
Journal articles inserm-01260985v1
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Assembly of chemically modified G-rich sequences into tetramolecular DNA G-quadruplexes and higher order structures

Jun Zhou , Dursun Nizam Korkut , Frédéric Rosu , Samir Amrane , Valérie Gabelica
Methods, 2014, Nucleic Acids Nanotechnology, 67, pp.159 - 168. ⟨10.1016/j.ymeth.2014.01.004⟩
Journal articles inserm-01385785v1
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A pilgrim's guide to G-quadruplex nucleic acid folding

Valérie Gabelica
Biochimie, 2014, 105, pp.1 - 3. ⟨10.1016/j.biochi.2014.08.007⟩
Journal articles inserm-01385787v1
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Assembly of Palladium(II) and Platinum(II) Metallo-Rectangles with a Guanosine-Substituted Terpyridine and Study of Their Interactions with Quadruplex DNA

Sushobhan Ghosh , Oscar Mendoza , Leticia Cubo , Frederic Rosu , Valérie Gabelica
Chemistry - A European Journal, 2014, 20 (16), pp.4772 - 4779. ⟨10.1002/chem.201304905⟩
Journal articles inserm-01387138v1
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Native Electrospray Mass Spectrometry of DNA G-Quadruplexes in Potassium Solution

Adrien Marchand , Valérie Gabelica
Journal of The American Society for Mass Spectrometry, 2014, 25 (7), pp.1146. ⟨10.1007/s13361-014-0890-3⟩
Journal articles inserm-01385783v1
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Ammonium ion binding to DNA G-quadruplexes: do electrospray mass spectra faithfully reflect the solution-phase species?

Françoise Balthasart , Janez Plavec , Valérie Gabelica
Journal of The American Society for Mass Spectrometry, 2013, 24 (1), pp.1-8. ⟨10.1007/s13361-012-0499-3⟩
Journal articles inserm-00980848v1
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Multiple and cooperative binding of fluorescence light-up probe Thioflavin T with human telomere DNA G-quadruplex

Valérie Gabelica , Ryuichi Maeda , Takeshi Fujimoto , Hidenobu Yaku , Takashi Murashima
Biochemistry, 2013, 52, pp.5620 - 5628. ⟨10.1021/bi4006072⟩
Journal articles inserm-01388017v1

Zwitterionic i-motif structures are preserved in DNA negatively charged ions produced by electrospray mass spectrometry

Frédéric Rosu , Valérie Gabelica , Laure Joly , Gilles Grégoire , E. de Pauw
Physical Chemistry Chemical Physics, 2010, 12 (41), pp.13448-13454
Journal articles hal-00533459v1

Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders

David Monchaud , Clémence Allain , Hélène Bertrand , Nicolas Smargiasso , Frédéric Rosu
Biochimie, 2008, 90 (8), pp.1207-1223. ⟨10.1016/j.biochi.2008.02.019⟩
Journal articles hal-00311781v1

Infrared Signature of DNA G-quadruplexes in the Gas Phase

Valérie Gabelica , Frédéric Rosu , E. de Pauw , Joël Lemaire , Jean-Christophe Gillet
Journal of the American Chemical Society, 2008, 130, pp.1810
Journal articles hal-00434106v1

Stabilization and structure of telomeric and c-myc region intramolecular G-quadruplexes: the role of central cations and small planar ligands.

Valérie Gabelica , Erin S. Baker , Marie-Paule Teulade-Fichou , Edwin de Pauw , Michael T. Bowers
Journal of the American Chemical Society, 2007, 129 (4), pp.895-904. ⟨10.1021/ja065989p⟩
Journal articles hal-00258139v1

Collision cross sections of phosphoric acid cluster anions and their use as calibrants for traveling wave ion mobility

Hélène Lavanant , Valentina Calabrese , Frédéric Rosu , Valérie Gabelica , Carlos Afonso
67th ASMS Conference on Mass Spectrometry and Allied Topics, Jun 2019, Atlanta, United States
Conference papers hal-03018411v1

Ion mobility:How to reconstruct collision cross section distributions from arrival time distributions measured in drift tube IMS

Adrien Marchand , Sandrine Livet , Frédéric Rosu , Valérie Gabelica
ASMS 2017 65th ASMS Conference on Mass Spectrometry and Allied Topics, Jun 2017, Indianapolis, United States
Conference papers hal-01547797v1

Ion Mobility Spectrometry: Towards Standard Operating Procedures (Ion Mobility MS Interest Group workshop report)

Valérie Gabelica , Brian H Clowers , Stephen J Valentine
65th ASMS Conference on Mass Spectrometry and Allied Topics, ASMS, Jun 2017, Indianapolis, United States
Conference papers hal-01557049v1
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Cation binding to nucleic acids

Adrien Marchand , Clémence Rabin , Sandrine Livet , Solenne Delahaye , Valentina d'Atri
ASMS 2016 64th ASMS Conference on Mass Spectrometry and Allied Topics, Jun 2016, San Antonio, United States
Conference papers hal-01562180v1
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Multi-scale Simulations Coupled with Ion Mobility Experiments Reveal the Fate of Nucleic Acids in the Gas Phase

Massimiliano Porrini , Clémence Rabin , Josephine Abi-Ghanem , Frédéric Rosu , Leonardo Darré
64th ASMS Conference on Mass Spectrometry and Allied Topics, Jun 2016, San Antonio, United States
Conference papers hal-01562153v1
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What happens to DNA duplexes in the gas phase?

Massimiliano Porrini , Frédéric Rosu , Valérie Gabelica
63rd ASMS Conference on Mass Spectrometry and Allied Topics (ASMS 2015), May 2015, St Louis, United States. , Proceedings of the ASMS Annual Conference 2015 St. Louis, 2015
Conference poster hal-01562195v1
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Ion Mobility -Mass Spectrometry: An Overview

Valérie Gabelica
Frank Sobott; Alison Ashcroft. Ion Mobility-Mass Spectrometry: Fundamentals and Applications, Royal Society of Chemistry, pp.1-25, 2021, New Developments in Mass Spectrometry, 978-1-83916-166-7. ⟨10.1039/9781839162886-00001⟩
Book sections hal-03463389v1