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Valérie LE CLERC

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**Valérie LE CLERC** Date of birth: October 15, 1972 (France) Professional address: AGROCAMPUS OUEST 2, rue André Le Nôtre 49045 Angers Cedex 01. France Email address: valerie.leclerc@agrocampus-ouest.fr Phone: + 33 241 225 433 Campus du végétal, Bâtiment A, bureau A1.19 42 Rue Georges Morel- BP 60057- 49071 Beaucouzé Cedex, France **EMPLOYMENT** Current position since January 2005 Associate Professor at the school Agrocampus Ouest Angers, http://www.agrocampus-ouest.fr/infoglueDeliverLive/ Department: Plant Sciences applied to Agriculture and Horticulture Laboratory: JRU IRHS ‘Research Institute on Horticulture and Seeds (INRA/AO/UA)‘ https://www6.angers-nantes.inra.fr/irhs Research team: QuaRVeg ‘Quality and Resistance to pests and diseases in Vegetables’ Skills: plant resistance, quantitative genetics, plant pathology, plant breeding RESEARCH INTEREST Main research: Study of the genetic determinism of carrot resistance to Alternaria dauci QTLs were identified in different genetic backgrounds, environments and with different scoring methods. Functional analysis of carrot resistance to Alternaria dauci is under progress in order to identify some mQTLS (metabolite QTLs) which are involved in carrot resistance to A. dauci and could explain the identified QTLs. Other projects: Multiresistance to pathogens (Alternaria radicina and Xanthomonas hortorum pv. carotae) Developing new phenotyping methods to evaluate carrot resistance Understanding the interaction between biotic and abiotic stresses; assessing the determinants involved in root quality and resistance to A. dauci **TEACHING AREAS** Horticulture Vegetable and seed production and chain Genetic resources EDUCATION 2001, Ph. D in cellular and molecular plant biology, University of Angers, France Title: “Evaluation of carrot genetic diversity (Daucus carota L.): strategies for analyses and regeneration of genetic resources “ Based on molecular markers, new methodologies were developed for the characterization, conservation and regeneration of carrot accessions of the “National collection of Carrot and others Daucus”. **OTHER PROFESSIONAL EXPERIENCES** August 14- Aug. 15 Visiting scholar- NCSU, Raleigh (NC, USA) in Plant Pathology Department, Peter Balint-Kurti lab. Maize resistance to Cochliobolus hetersostrophus and Belonolaimus longicaudatus. April 01- July. 03 Scientist – ECPGR research project « The future of European carrot », INH, Angers August 03- Sept. 04 Research engineer – BioGEVES Laboratory, Surgères (France) Oct. 04- Dec. 04 Research engineer – GEVES, Brion (France)

Publications

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Co-Localization of Resistance and Metabolic Quantitative Trait Loci on Carrot Genome Reveals Fungitoxic Terpenes and Related Candidate Genes Associated with the Resistance to Alternaria dauci

Claude Emmanuel Koutouan , Valérie Le Clerc , Anita Suel , Latifa Hamama , Patricia Claudel
Metabolites, 2023, 13 (1), pp.71. ⟨10.3390/metabo13010071⟩
Journal articles hal-03923129v1
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Role of Phenylpropanoids and Flavonoids in Plant Resistance to Pests and Diseases

Marie-Louisa Ramaroson , Claude Koutouan , Jean-Jacques Helesbeux , Valérie Le Clerc , Latifa Hamama
Molecules, 2022, 27 (23), pp.8371. ⟨10.3390/molecules27238371⟩
Journal articles hal-04053646v1
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Multisite evaluation of phenotypic plasticity for specialized metabolites, some involved in carrot quality and disease resistance

Wilfried Chevalier , Sitti-Anlati Moussa , Miguel Medeiros Netto Ottoni , Cécile Dubois-Laurent , Christophe Aubert
PLoS ONE, 2021, 16 (4), pp.e0249613. ⟨10.1371/journal.pone.0249613⟩
Journal articles hal-03192279v1

Carrot resistance against Alternaria leaf blight: potential involvement of terpenes and flavonoids

C. Koutouan , M. Briard , R. Baltenweck , P. Claudel , D. Halter
Acta Horticulturae, 2019, II International Symposium on Carrot and Other Apiaceae, 1264, pp.191-198. ⟨10.17660/ActaHortic.2019.1264.23⟩
Journal articles hal-02915477v1

Breeding for carrot resistance to Alternaria dauci without compromising taste

Valérie Le Clerc , Christophe Aubert , Valentine Cottet , Claire Yovanopoulos , Mathilde Piquet
Molecular Breeding, 2019, 39 (4), pp.59. ⟨10.1007/s11032-019-0966-7⟩
Journal articles hal-02277516v1

Des carottes résistantes à l'alternariose et peu amères, c'est possible!

Valérie Le Clerc , D. Bodiou
Culture légumière, 2019, 174, pp.24-25
Journal articles hal-02915451v1
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Link between carrot leaf secondary metabolites and resistance to Alternaria dauci

Claude Koutouan , Valérie Le Clerc , Raymonde Baltenweck , Patricia Claudel , David Halter
Scientific Reports, 2018, 8 (1), pp.13746. ⟨10.1038/s41598-018-31700-2⟩
Journal articles hal-02516664v1

Combined Alternaria dauci infection and water stresses impact carotenoid content of carrot leaves and roots

Florent Perrin , Sébastien Huet , Cécile Dubois-Laurent , Yves Gibon , Sylvie Citerne
Environmental and Experimental Botany, 2017, 143, pp.125-134. ⟨10.1016/j.envexpbot.2017.09.004⟩
Journal articles hal-02053534v1
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Recherche de l'origine de l'absence de germination des semences de carotte

Coraline Ravenel , Emmanuel Laurent , Marie-Laure Casals , Françoise Corbineau , Valérie Le Clerc
Innovations Agronomiques, 2016, 50, pp.11-19. ⟨10.15454/1.4721075025751228E12⟩
Journal articles hal-04678844v1

QTL mapping of carrot resistance to leaf blight with connected populations: stability across years and consequences for breeding

Valérie Le Clerc , Sabrina Marques , Anita Suel , Latifa Hamama , Linda Voisine
TAG Theoretical and Applied Genetics, 2015, 128 (11), pp.2177-2187. ⟨10.1007/s00122-015-2576-z⟩
Journal articles hal-01412605v1
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Is there variety × isolate interaction in the polygenic quantitative resistance of carrot to Alternaria dauci ?

Valérie Le Clerc , Anita Suel , A. Pawelec , Sabrina Marques , Sébastien Huet
Euphytica, 2015, 202 (2), pp.235-243. ⟨10.1007/s10681-014-1279-x⟩
Journal articles hal-01392648v1

Évolution temporelle de la diversité génétique de Chaerophyllum bulbosum : conséquences sur la gestion des ressources génétiques

Valérie Le Clerc , Anita Suel , Emmanuel E. Geoffriau , Sébastien Huet , Mathilde Briard
Comptes Rendus Biologies, 2014, 337 (5), pp.352-359. ⟨10.1016/j.crvi.2014.03.008⟩
Journal articles hal-01209976v1

Inhibitory effects of the carrot metabolites 6-methoxymellein and falcarindiol on development of the fungal leaf blight pathogen Alternaria dauci

Mickaël Lecomte , Romain Berruyer , Latifa Hamama , Cora Boedo , Piétrick Hudhomme
Physiological and Molecular Plant Pathology, 2012, 80, pp.58 - 67. ⟨10.1016/j.pmpp.2012.10.002⟩
Journal articles hal-01128455v1
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Inter simple sequence repeat fingerprints for assess genetic diversity of tunisian garlic populations

Naouel Jabbes , Emmanuel E. Geoffriau , Valérie Le Clerc , Boutheina Dridi , Chérif Hannechi
Journal of Agricultural Science, 2011, 3 (4), pp.77-85
Journal articles hal-00729284v1

Evaluating aggressiveness and host range of Alternaria dauci in a controlled environment

C. Boedo , S. Benichou , R. Berruyer , S. Bersihand , A. Dongo
Plant Pathology, 2011, 61 (1), pp.63-75. ⟨10.1111/j.1365-3059.2011.02494.x⟩
Journal articles hal-00729318v1

Evaluation of different methods for the characterization of carrot resistance to the alternaria leaf blight pathogen (Alternaria dauci) revealed two qualitatively different resistances

C. Boedo , R. Berruyer , M. Lecomte , S. Bersihand , Mathilde Briard
Plant Pathology, 2010, 59 (2), pp.368-375. ⟨10.1111/j.1365-3059.2009.02218.x⟩
Journal articles hal-00729504v1

Genetic architecture of factors underlying partial resistance to Alternaria leaf blight in carrot.

Valérie Le Clerc , A. Pawelec , C. Birolleau-Touchard , A. Suel , Mathilde Briard
TAG Theoretical and Applied Genetics, 2009, 118 (7), pp.1251-9. ⟨10.1007/s00122-009-0978-5⟩
Journal articles hal-00729213v1

Impact of carrot resistance on development of the Alternaria leaf blight pathogen (Alternaria dauci)

Cora Boedo , Valérie Le Clerc , Mathilde Briard , Philippe Simoneau , Michel Chevalier
European Journal of Plant Pathology, 2008, 121 (1), pp.55-66. ⟨10.1007/s10658-007-9241-6⟩
Journal articles hal-02661624v1

Indicators to assess temporal genetic diversity in the French Catalogue: no losses for maize and peas

Valérie Le Clerc , Valerie Cadot , M. Canadas , François Boulineau , Joelle Lallemand
TAG Theoretical and Applied Genetics, 2006, 113 (7), pp.1197-1209. ⟨10.1007/s00122-006-0368-1⟩
Journal articles hal-02660974v1
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Identification of duplicates for the optimization of carrot collection management

Valérie Le Clerc , A. Suel , M. Briard
Biodiversity and Conservation, 2005, 14 (5), pp.1211-1223. ⟨10.1007/s10531-004-7847-y⟩
Journal articles hal-02677472v1

Influence of number and map distribution of AFLP markers on similarity estimates in carrot

Valérie Le Clerc , M. Briard , P. Revollon
TAG Theoretical and Applied Genetics, 2002, 106 (1), pp.157-162
Journal articles hal-02674488v1
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Resistant carrots to Alternaria dauci or tasty carrots: should we choose?

V. Le Clerc , C Aubert² , V. Cottet , C. Yovanopoulos , M. Piquet
II International Symposium on Carrot and Other Apiaceae, Sep 2018, Cracovie, Poland. pp.199-204, ⟨10.17660/ActaHortic.2019.1264.24⟩
Conference papers hal-02469328v1

Is the host range of Alternaria dauci restricted to carrot?

Cora Boedo , Soumaya Benichou , Romain Berruyer , Stéphanie Bersihand , A. Dongo
International Symposium on Carrot and Other Apiaceae, International Society for Horticultural Science (ISHS). INT., 2017, Angers, France. pp.183-189, ⟨10.17660/ActaHortic.2017.1153.26⟩
Conference papers hal-02516596v1

Carrot resistance to Alternaria leaf blight: from genetics to metabolomics

Valérie Le Clerc , Claude Koutouan , Mathilde Piquet , Anita Suel , Sébastien Huet
State-of-the-art technologies: challenge for the research in Agricultural and Food Sciences, 2016, Belgrade, Serbia
Conference papers hal-02516448v1

The Ins and Outs of Carrot Genetics and Disease Resistance

Valérie Le Clerc
NC State University Research seminar, 2014, Raleigh, United States
Conference papers hal-03284065v1

Genetic diversity and taxonomic aspects of wild carrot in France

Emmanuel E. Geoffriau , J.-P. Reduron , Audrey Cadou , Mohamed Maghraoui , M. Jourdan
International Symposium on Carrot and other Apiaceae, International Society for Horticultural Science (ISHS). INT., Sep 2014, Angers, France. pp.304, ⟨10.17660/ActaHortic.2017.1153.38⟩
Conference papers hal-02737583v1

Is host range of carrot restricted to Alternaria dauci?

Cora Boedo , Soumaya Benichou , Romain Berruyer , Stéphanie Bersihand , A. Dongo
Carrot and other Apiaceae International Symposium, 2014, Angers, France
Conference papers hal-03339435v1

Wild carrot diversity in continental France and Corsica

Emmanuel E. Geoffriau , Audrey Chaput-Bardy , Matthieu Jourdan , Mohamed Maghraoui , Cécile Dubois-Laurent
36th International Carrot Conference, Workshop on the use of carrot crop wild relatives (Global Crop Diversity Trust), 2013, Madison, United States
Conference papers hal-03284054v1

Evaluation dans différentes conditions environnementales de la résistance des variétés de carotte à Alternaria dauci : prise en compte du stade de développement de la plante et de l'agressivité de la souche

S. Marques , V. Cadot , S. Bersihand , A. Suel , S. Huet
6ème Rencontres du végétal, Jan 2011, Angers (FR), France
Conference papers hal-00729356v1

Alternaria dauci, agent causal des brûlures foliaires est pathogène sur différentes espèces végétales

C. Boedo , S. Benichou , S. Bersihand , Philippe Simoneau , P. Poupard
6ème Rencontres du végétal, Agrocampus Ouest-centre d'Angers, Jan 2011, Angers (FR), France
Conference papers hal-00729333v1

Is quantitative resistance qualitative? An example with two Alternaria Leaf Blight resistant carrot genotypes and four resistance assessment techniques

Cora Boedo , Mickaël Lecomte , Stéphanie Bersihand , Sabrina Marques , Pascal Poupard
34 th International Carrot Conference, 2010, Kennewick, United States
Conference papers hal-03339406v1

Comment mesurer la résistance quantitative de la carotte à Alternaria dauci ? Comparaison de différentes méthodes.

Cora Boedo , Romain Berruyer , Mickaël Lecomte , Stéphanie Bersihand , Mathilde Briard
7. Colloque National de la Société Française de Phytopathologie, Jun 2009, Lyon, France. 1 p
Conference papers hal-02822617v1

Genetic resources management with networks: the example of the network "Carrot and other Daucus"

Mathilde Briard , Valérie Le Clerc , Didier Peltier , Anita Suel , Jacky Granger
Second International Symposium on Plant Genetic Resources of Horticultural Crops, Aug 2006, Seoul, South Korea
Conference papers hal-02757432v1

Tuberous-rooted chervil

Mathilde Briard , Valérie Le Clerc , Sébastien Huet , Jacky Granger , Emmanuel E. Geoffriau
Carrots and related Apiaceae crops, CABI, pp.325-332, 2020, 9781789240955. ⟨10.1079/9781789240955.0325⟩
Book sections hal-03144635v1

Genetics and Genomics of Carrot Biotic Stress

Lindsey Du Toit , Valérie Le Clerc , Mathilde Briard
Philipp W. Simon; Massimo Iorizzo; Dariusz Grzebelus. The Carrot Genome, Chapter 18, Springer International Publishing, pp.317-362, 2019, Compendium of Plant Genomes, 978-3-030-03388-0. ⟨10.1007/978-3-030-03389-7_18⟩
Book sections hal-02277605v1
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Etude de la résistance partielle de la carotte à Alternaria dauci par une approche de phénotypage multi critères

Valérie Le Clerc , Elodie Auperpin , Anita Suel , David Rousseau , Etienne Belin
Other publications hal-02516459v1

Création variétale d’espèces potagères résistantes aux bioagresseurs

Valérie Le Clerc , Mathilde Briard
2012, n.p
Other publications hal-00925206v1

Effets inhibiteurs de la phytoalexine 6-méthoxymelléine sur le développement d’Alternaria dauci, agent de la brûlure foliaire de la carotte

M. Lecomte , L. Hamama , C. Boedo , P. Hudhomme , S. Bersihand
2012, n.p
Other publications hal-00925207v1

La phytoalexine ?6-méthoxymelléine' est-elle impliquée dans les mécanismes de résistance de la carotte à Alternaria dauci, agent de la brûlure foliaire ?

M. Lecomte , C. Boedo , S. Bersihand , L. Hamama , A. Joubert
2010, non paginé
Other publications hal-00729554v1

Comment mesurer la résistance quantitative de la carotte à Alternaria dauci ? Comparaison de différentes méthodes

C. Boedo , R. Berruyer , M. Lecomte , S. Bersihand , Mathilde Briard
2009, non paginé
Other publications hal-00729975v1

Peut-on cartographier les facteurs de résistance de la carotte à Alternaria dauci, à l'aide de marqueurs dominants sur une descendance F2?

A. Pawelec , Valérie Le Clerc , C. Birolleau-Touchard , A. Suel , Mathilde Briard
2009, non paginé
Other publications hal-00730042v1

Assessment of Alternaria dauci host range and preliminary study of fungal phytotoxic components

P. Hudhomme , C. Boedo , Mathilde Briard , Valérie Le Clerc , T. Guillemette
2008, non paginé
Other publications hal-00729101v1