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Vincent Jonchere

Vincent Jonchère, Researcher in UMR Birds Biology and poultry porduction (BOA)
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Presentation

Docteur en biologie de la reproduction et du développement, l’essentiel de mes travaux de recherche a porté sur l’étude de la biologie des épithéliums dans de nombreux modèles physiologiques. J’ai étudié les mécanismes responsables de la formation de la coquille d’œuf chez la poule, les effets du stress périnatal chez le xénope et plus récemment les conséquences de l’instabilité génomique dans différents tissus digestifs chez l’humain. Ma thématique de recherche au sein de l’UMR BOA vise à identifier les mécanismes de programmation précoce des fonctionnalités digestives afin d’améliorer et de diversifier l’utilisation des ressources alimentations. J’étude les conséquences d’une modulation de l’alimentation durant la période périnatale sur le développement des fonctionnalités digestives des oiseaux d'élevage
Doctor in Reproductive and Developmental Biology, the core of my research has focused on the study of epithelial biology in various physiological models. I have investigated the mechanisms responsible for eggshell formation in chickens, the effects of perinatal stress in Xenopus Tropicalis, and the consequences of genomic instability in different digestive tissues in humans. Within the UMR BOA, my research theme aims to identify early programming mechanisms of digestive functionalities to enhance and diversify the use of food resources. I explore the consequences of modulating nutrition during the perinatal period on the development of digestive functionalities in poultry.

Publications

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Transcriptome and Methylome Analysis Reveal Complex Cross-Talks between Thyroid Hormone and Glucocorticoid Signaling at Xenopus Metamorphosis

Nicolas Buisine , Alexis Grimaldi , Vincent Jonchere , Muriel Rigolet , Corinne Blugeon
Cells, 2021, 10 (9), pp.2375. ⟨10.3390/cells10092375⟩
Journal articles hal-03364443v1
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Adrenal gland as a sanctuary site for immunotherapy in patients with microsatellite instability-high metastatic colorectal cancer

Romain Cohen , Vincent Jonchère , Christelle de La Fouchardière , Toky Ratovomanana , Quentin Letourneur
Journal for Immunotherapy of Cancer, 2021, 9 (2), pp.e001903. ⟨10.1136/jitc-2020-001903⟩
Journal articles hal-03141378v1

Thyroid hormone effects on the methylome during post-embryonic development

Vincent Jonchère , Nicolas Buisine , Corinne Blugeon , Laurent Sachs
Journal of the Endocrine Society, 2019, ENDO 2019 Abstracts - 101st Annual Meeting of the Endocrine Society – March 23 – 26th, 2019 – New Orleans, Louisiana 3 (Supplement_1), ⟨10.1210/js.2019-SAT-551⟩
Journal articles hal-02928599v1
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MSI/MMR-deficient tumor diagnosis: Which standard for screening and for diagnosis? Diagnostic modalities for the colon and other sites: Differences between tumors

Magali Svrcek , Olivier Lascols , Romain Cohen , Ada Collura , Vincent Jonchère
Bulletin du Cancer, 2019, 106 (2), pp.119-128. ⟨10.1016/j.bulcan.2018.12.008⟩
Journal articles hal-02179325v1

Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability

A'Dem Bokhari , Vincent Jonchère , Anaïs Lagrange , Romane Bertrand , Magali Svrcek
Oncogenesis, 2018
Journal articles hal-03071655v1
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Identification of Positively and Negatively Selected Driver Gene Mutations Associated With Colorectal Cancer With Microsatellite Instability Positive Selection Pressure Mutational Background Negative Selection Pressure Mutational Frequency Microsatellite length (bp)

Vincent Jonchère , Laetitia Marisa , Malorie Greene , Alain Virouleau , Olivier Buhard
Cellular and Molecular Gastroenterology and Hepatology, 2018, 6 (3), pp.277-300. ⟨10.1016/j.jcmgh.2018.06.002⟩
Journal articles hal-02180261v1

The Balance Between Cytotoxic T-cell Lymphocytes and Immune Checkpoint Expression in the Prognosis of Colon Tumors

Laetitia Marisa , Magali Svrcek , Ada Collura , Etienne Becht , Pascale Cervera
JNCI: Journal of the National Cancer Institute, 2018, 110 (1), pp.68-77. ⟨10.1093/jnci/djx136⟩
Journal articles hal-01727817v1
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Transcriptional responses to hyperplastic MRL signalling in Drosophila

Vincent Jonchère , Nada Alqadri , John Herbert , Lauren Dodgson , David Y. Mason
Open Biology, 2017, 7 (2), pp.160306. ⟨10.1098/rsob.160306⟩
Journal articles hal-03071683v1

Dlx5 and Dlx6 control uterine adenogenesis during post-natal maturation: possible consequences for endometriosis

Brice Bellessort , Marine Le Cardinal , Anne Bachelot , Nicolas Narboux-Nême , Paolo Garagnani
Human Molecular Genetics, 2015, 25 (1), pp.97-108. ⟨10.1093/hmg/ddv452⟩
Journal articles hal-02135783v1
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Validating RNAi Phenotypes in Drosophila Using a Synthetic RNAi-Resistant Transgene

Vincent Jonchère , Daimark Bennett
PLoS ONE, 2013, 8 (8), pp.e70489. ⟨10.1371/journal.pone.0070489⟩
Journal articles hal-03071690v1
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PNUTS/PP1 Regulates RNAPII-Mediated Gene Expression and Is Necessary for Developmental Growth

Anita Ciurciu , Louise Duncalf , Vincent Jonchère , Nick Lansdale , Olga O. Vasieva
PLoS Genetics, 2013, 9 (10), pp.e1003885. ⟨10.1371/journal.pgen.1003885⟩
Journal articles hal-03073712v1
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Identification of uterine ion transporters for mineralisation precursors of the avian eggshell

Vincent Jonchère , Aurélien Brionne , Joël Gautron , Yves Y. Nys
BMC Physiology, 2012, 12, 17 p. ⟨10.1186/1472-6793-12-10⟩
Journal articles hal-02642183v1
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Structure, propriétés et minéralisation de la coquille de l'œuf : rôle de la matrice organique dans le contrôle de sa fabrication

Yves Y. Nys , M.-T. Hincke , A. Hernandez-Hernandez , A.-B. Rodriguez-Navarro , J. Gomez-Morales
INRA Productions Animales, 2010, 23 (2), pp.143-154
Journal articles hal-02667365v1
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Gene expression profiling to identify eggshell proteins involved in physical defense of the chicken egg

Vincent Jonchère , Sophie Réhault-Godbert , Christelle Hennequet-Antier , Cédric Cabau , Vonick Sibut
BMC Genomics, 2010, 11 (57), 19 p. ⟨10.1186/1471-2164-11-57⟩
Journal articles hal-02662318v1
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L'apport des techniques à haut débit (protéomique et transcriptomique) dans l'identification et la caractérisation fonctionnelle des protéines de l'oeuf

Joël Gautron , Sophie Réhault-Godbert , Vincent Jonchère , Virginie Herve-Grepinet , K. Mann
INRA Productions Animales, 2010, 23 (2), pp.133-140
Journal articles hal-02666661v1

Impacts of early nutritional strategies on digestive functionalities of chicks

Vincent Jonchère , Marlies van den Nieuwenhof , Léa Cornaille , Justine Jimenez , Théophane de Rauglaudre
XVI European Poultry Conference, Jun 2024, Valence, Spain
Conference papers hal-04661421v1

Impacts à court terme de stratégies nutritionnelles précoces sur l'homéostasie digestive des poussins

Vincent Jonchère , Marlies van den Nieuwenhof , Léa Cornaille , Justine Jimenez , Théophane de Rauglaudre
15. Journées de la Recherche Avicole et Palmipèdes à Foie gras, Mar 2024, Tours, France
Conference papers hal-04661447v1
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Impacts à court et à moyen terme d'une supplémentation précoce en xylanase-xos sur le métabolome et le microbiome caécal des poulets de chair

Vincent Jonchère , Françoise I. Bussière , Vahid Khaksar , Michel Jacques M.J. Duclos , Léa Cornaille
14 ème Journées de la Recherche Avicole et Palmipèdes à Foie Gras (JRA), Mar 2022, Tours, France
Conference papers hal-03775492v1

Differentiated short and medium term impacts of early xylanase-xos supplementation on caecal metabolome and microbiome moy in broiler

Vincent Jonchère , Françoise I. Bussière , Vahid Khaksar , Michel Jacques M.J. Duclos , Léa Cornaille
World Poultry Congress, Aug 2022, Paris, France
Conference papers hal-04144164v1

Identification of positively and negatively selected driver gene mutations associated with colorectal cancer with microsatellite instability

Vincent Jonchère , Ada Collura , Alex Duval
Annual SMB Meetings – Society for Mathematical Biology, Jun 2021, Online, Germany
Conference papers hal-03262153v1

Thyroid Hormone effects on the methylome during Post-embryonic development

Vincent Jonchère , Alexis Grimaldi , Nicolas Buisine , Laurent Sachs
Journée de Séminaires du Département Phase sur l'Epigénétique EpiPhase, Jun 2021, Lyon - Online, France
Conference papers hal-03262140v1

DNA methylation landscape changes during thyroid hormone and glucocorticoid crosstalks at Xenopus metamorphosis.

Vincent Jonchère , Corinne Blugeon , J. Pouch , Laurent Sachs , Nicolas Buisine
ISAREN (International Symposium on Amphibian and Reptile Endocrinology): Epigenetic Analysis in Amphibian and Reptile Endocrinology and Neurobiology, 5th Biennial North American Society for Comparative Endocrinology, 2019, Gainesville, United States
Conference papers hal-03072421v1

Identification of positively and negatively selected driver gene mutations associated with colorectal cancer with microsatellite instability.

Vincent Jonchère , Ada Collura , Alex Duval
Seminaire Carte d’Identité des Tumeurs, 2018, Paris, France
Conference papers hal-03072770v1

Corticosterone affects thyroid hormones induced modifications of the methylome.

Vincent Jonchère , Nicolas Buisine , Corinne Blugeon , Laurent Sachs
41th Annual Meeting of the European Thyroid Association, 2018, Newcastle, United Kingdom
Conference papers hal-03072572v1

Stress sensitivity of limb development in Xenopus Tropicalis Tadpoles.

Alexis Grimaldi , Nicolas Buisine , Vincent Jonchère , Corinne Blugeon , Laurent Sachs
IDEAL Final Meeting 2015, 2015, Leiden, Netherlands
Conference papers hal-03072974v1

Molecular crosstalk between thyroid hormones & glucocorticoides affects skeleton development.

Vincent Jonchère , Alexis Grimaldi , Nicolas Buisine , Laurent Sachs
IDEAL annual meeting, 2014, Leiden, Netherlands
Conference papers hal-03073190v1

Identification of transcriptional targets & mechanisms of MRL proteins to promote cell cycle progression /growth

Vincent Jonchère , Daimark Bennett
Bioinformatics/computational biology/systems biology seminar, 2013, Liverpool, United Kingdom
Conference papers hal-03073291v1

Growth control by the actin cytoskeleton: transcriptional targets of MRL/SRF signaling

Vincent Jonchère , Lauren Dodgson , Daimark Bennett
Fly meeting, 2012, Manchester, France
Conference papers hal-03073379v1

Gene identification coding uterine proteins supplying the minerals for eggshell formation

Vincent Jonchère , Joël Gautron , Agnès Narcy , Aurélien Brionne , Yves Y. Nys
13. European Poultry Conference (EPC 2010), Aug 2010, Tours, France
Conference papers hal-02752419v1

Screening of novel uterine proteins involved in eggshell formation using cDNA microarrays

Vincent Jonchère , Sophie Réhault-Godbert , L. Cogburn , Christelle Hennequet-Antier , Cédric Cabau
19. European Symposium on the Quality of Poultry Meat. 13. European Symposium on the Quality of Eggs and Eggs Products., Jun 2009, Turku, Finland
Conference papers hal-02751521v1

Identification par une approche transcriptomique d'un ensemble de protéines potentiellement impliquées dans la formation de la coquille de l'oeuf de poule

Vincent Jonchère , Yves Y. Nys , L. Cogburn , Christelle Hennequet-Antier , Cédric Cabau
11. Journées Françaises de Biologie des Tissus Minéralisés, Mar 2009, Nice, France
Conference papers hal-02756159v1

Identification de nouveaux genes de la coquille potentiellement impliqués dans les défenses naturelles de l'oeuf

Vincent Jonchère , Sophie Réhault-Godbert , Christelle Hennequet , Cédric Cabau , Vonick Sibut
8. Journées de la Recherche Avicole, Mar 2009, Saint-Malo, France
Conference papers hal-02751014v1

Functional genomics reveals numerous novel egg proteins

Joël Gautron , K. Mann , P.G. Righetti , Sophie Réhault-Godbert , Vincent Jonchère
19. European Symposium on the Quality of Poultry Meat. 13. European Symposium on the Quality of Eggs and Eggs Products., Jun 2009, Turku, Finland
Conference papers hal-02755471v1

Comparison of statistical methods (t-test and mixed model) to identify differentially expressed genes between regions of the laying egg oviduct in loop design microarray experiment

Christelle Hennequet-Antier , Vincent Jonchère , Sophie Réhault-Godbert , L.A. Cogburn , Vonick Sibut
Journées ouvertes Biologie Informatique Mathématiques 2008, Jun 2008, Lille, France
Conference papers hal-02752405v1

Transcriptional profiling to identify novel antimicrobial egg proteins

Joël Gautron , Sophie Réhault-Godbert , Vincent Jonchère , L.A. Cogburn , Christelle Hennequet
23. World's Poultry Congress, Jun 2008, Brisbane, Australia
Conference papers hal-02757395v1

Identification of new chicken genes coding eggshell proteins potentially involved in the physical defence on the egg using cDNA arrays

Vincent Jonchère , Yves Y. Nys , L.A. Cogburn , Christelle Hennequet , Vonick Sibut
23. World's Poultry Congress, Jun 2008, Brisbane, Australia
Conference papers hal-02752448v1

Use of high-throughput technologies to identify new egg components with novel biological activities

Joël Gautron , Sophie Réhault-Godbert , Vincent Jonchère , Virginie Herve-Grepinet , Yves Y. Nys
International Egg Symposium: "The Return of the Good Egg", Nov 2008, Istanbul, Turkey
Conference papers hal-02757347v1

Use of high-throughput methods to identify novel egg components

Joël Gautron , Vincent Jonchère , Christelle Hennequet-Antier , Cédric Cabau , Valérie Labas
25. Congrès de la Société d'Electrophorèse et d'Analyse Protéomique, Oct 2008, Tours, France
Conference papers hal-02751763v1

Transcriptional profiling to identify hen egg proteins involved in the egg's natural defences

Vincent Jonchère , Larry A. Cogburn , Christelle Hennequet , Wilfrid Carre , Vonick Sibut
18. European Symposium on the Quality of Poultry Meat, Sep 2007, Prague, Czech Republic
Conference papers hal-02757086v1

Comparative analysis of transcriptional profiles of chicken jejunum and derived organoids collected early post-hatch

Vincent Jonchère , Tiffany Pézier , Agnès Wiedemann , Léa Cornaille , Gaëlle Lefort
XVI. European Poultry Conference, Jun 2024, Valencia (Espagne), Spain
Conference poster hal-04709977v1

Identification of negatively selected driver gene mutations associated with colorectal cancer with microsatellite instability.

Vincent Jonchère , Laëtitia Marisa , Malorie Greene , Ada Collura , Alex Duval
Gordon Conference: DNA Damage, mutations and cancer, 2018, Ventura, United States
Conference poster hal-03071728v1

Glucocorticoids affect gene regulation by thyroid hormones during limb development in Xenopus tropicalis.

Alexis Grimaldi , Nicolas Buisine , Vincent Jonchère , Corinne Blugeon , Laurent Sachs
ENDO Annual Meeting 2015, 2015, San Diego, France
Conference poster hal-03071759v1

Growth control by the actin cytoskeleton: transcriptional targets of MRL/SRF signaling.

Vincent Jonchère , Daimark Bennett
CRUK Annual Meeting, 2012, Liverpool, United Kingdom
Conference poster hal-03071951v1

Studying bio markers of ovulation by proteomic analysis

Vincent Jonchère , Valérie Labas , Cécile Lahuec , Nadine Gérard
Congrès de la Société Française d'Electrophorèse et d'Analyse Protéomique, Oct 2006, Saint-Malo, France. n.p., 2006
Conference poster hal-02812338v1

In vitro effect of interleukin-1b (IL-1b) and interleukin-1 receptor antagonist (IL-1RA) on equine oocyte maturation and on cumulus cells genes expression

Maud Caillaud , Cécile Lahuec , Vincent Jonchère , Nadine Gérard
ESHRE Campus 2005 : Mammalian Oogenesis and Folliculogenesis, Mar 2005, Paris, France. 2005
Conference poster hal-02759309v1