Violaine Sée Full Professor of Cell Biology

Identifiants chercheurs

IdHAL :

violaine-see

ORCID :

0000-0001-6384-8381

Présentation

My research focuses on the cellular response to environmental oxygen level variations and their impact on cell fate. I have worked for 19 years at the University of Liverpool, where I investigated the role of hypoxia on cancer cell phenotype, especially in paediatric (neuroblastoma, medulloblastoma) and adult brain tumours (glioblastoma). In 2021, I have joined the University Claude Bernard Lyon 1, where I work on the role of hypoxa on skin cells, in the context of skin ageing, wound healing and dermal fibrosis.

Publications

Pré-publication, Document de travail (2)

Inhibition of glioblastoma cell proliferation and invasion by the choline-kinase inhibitor JAS239 varies with cell type and hypoxia Claire Louise Kelly,Martyna Wydrzynska,Marie Phelan,Sofya Osharovich,Edward Delikatnyet al. 2024 Pré-publication, Document de travail hal-04852423v1
USP29 is a novel non-canonical Hypoxia Inducible Factor-α activator Amelie Schober,Inés Martín-Barros,Teresa Martín-Mateos,Encarnación Pérez-Andrés,Onintza Carlevariset al. 2024 Pré-publication, Document de travail hal-04852421v1

Article dans une revue (36)

Optical Tissue Clearing to Study the Intra-Pulmonary Biodistribution of Intravenously Delivered Mesenchymal Stromal Cells and Their Interactions with Host Lung Cells Alejandra Hernandez Pichardo,Francesco Amadeo,Bettina Wilm,Raphaël Lévy,Lorenzo Resselet al. International Journal of Molecular Sciences, 2022, 23 (22), pp.14171. ⟨10.3390/ijms232214171⟩ Article dans une revue hal-04852359v1
Downregulation of both mismatch repair and non-homologous end-joining pathways in hypoxic brain tumour cell lines Sophie Cowman,Barry Pizer,Violaine Sée PeerJ, 2021, 9, pp.e11275. ⟨10.7717/peerj.11275⟩ Article dans une revue hal-04852363v1
Oxygen-dependent changes in binding partners and post-translational modifications regulate the abundance and activity of HIF-1α/2α Leonard Daly,Philip Brownridge,Michael Batie,Sonia Rocha,Violaine Séeet al. Science Signaling, 2021, 14 (692), ⟨10.1126/scisignal.abf6685⟩ Article dans une revue hal-04843131v1
The Role of Hypoxia-Inducible Factor Post-Translational Modifications in Regulating Its Localisation, Stability, and Activity Adam Albanese,Leonard A Daly,Daniela Mennerich,Thomas Kietzmann,Violaine Sée International Journal of Molecular Sciences, 2020, 22, ⟨10.3390/ijms22010268⟩ Article dans une revue hal-04843156v1
CDK inhibitors reduce cell proliferation and reverse hypoxia-induced metastasis of neuroblastoma tumours in a chick embryo model Rasha Swadi,Keerthika Sampat,Anne Herrmann,Paul Losty,Violaine Séeet al. Scientific Reports, 2019, 9 (1), pp.9136. ⟨10.1038/s41598-019-45571-8⟩ Article dans une revue hal-04843291v1
Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells Sophie Cowman,Yuen Ngan Fan,Barry Pizer,Violaine Sée BMC Cancer, 2019, 19 (1), pp.300. ⟨10.1186/s12885-019-5476-9⟩ Article dans une revue hal-04843297v1
Optimising the chick chorioallantoic membrane xenograft model of neuroblastoma for drug delivery Rasha Swadi,Grace Mather,Barry Pizer,Paul Losty,Violaine Séeet al. BMC Cancer, 2018, 18 (1), pp.28. ⟨10.1186/s12885-017-3978-x⟩ Article dans une revue hal-04843310v1
Magnetic Resonance Imaging for Characterization of a Chick Embryo Model of Cancer Cell Metastases Anne Herrmann,Arthur Taylor,Patricia Murray,Harish Poptani,Violaine Sée Molecular Imaging, 2018, 17, ⟨10.1177/1536012118809585⟩ Article dans une revue hal-04843301v1
Effects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model Yousef Al-Mutawa,Anne Herrmann,Catriona Corbishley,Paul D. Losty,Marie Phelanet al. Bioscience Reports, 2018, 38 (4), ⟨10.1042/BSR20180185⟩ Article dans une revue hal-04843306v1
Use of infrared microspectroscopy to elucidate a specific chemical signature associated with hypoxia levels found in glioblastoma Christophe Sandt,Céline Nadaradjane,Rosalie Richards,Paul Dumas,Violaine Sée Analyst, 2016, 141 (3), pp.870-883. ⟨10.1039/c5an02112j⟩ Article dans une revue hal-04843341v1
Differential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and -2 alpha impacts on their stability and mobility S. Taylor,J. Bagnall,D. Mason,R. Levy,D. Ferniget al. Open Biology, 2016, 6 (9), pp.160195. ⟨10.1098/rsob.160195⟩ Article dans une revue hal-04843316v1
Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation John Ankers,Raheela Awais,Nicholas Jones,James Boyd,Sheila Ryanet al. eLife, 2016, 5, ⟨10.7554/eLife.10473⟩ Article dans une revue hal-04843333v1
Cell cycle progression in glioblastoma cells is unaffected by pathophysiological levels of hypoxia Rosalie Richards,Michael Jenkinson,Brian Haylock,Violaine Sée PeerJ, 2016, 4, pp.e1755. ⟨10.7717/peerj.1755⟩ Article dans une revue hal-04843336v1
Cellular memory of hypoxia elicits neuroblastoma metastasis and enables invasion by non-aggressive neighbouring cells A Herrmann,M Rice,R Lévy,B Pizer,P Lostyet al. Oncogenesis, 2015, 4 (2), pp.e138-e138. ⟨10.1038/oncsis.2014.52⟩ Article dans une revue hal-04843361v1
Modeling the dynamics of hypoxia inducible factor-1α (HIF-1α) within single cells and 3D cell culture systems Joseph Leedale,Anne Herrmann,James Bagnall,Andreas Fercher,Dmitri Papkovskyet al. Mathematical Biosciences, 2014, 258, pp.33-43. ⟨10.1016/j.mbs.2014.09.007⟩ Article dans une revue hal-04843357v1
Mir-34a Mimics Are Potential Therapeutic Agents for p53-Mutated and Chemo-Resistant Brain Tumour Cells Yuen Ngan Fan,Daniel Meley,Barry Pizer,Violaine Sée PLoS ONE, 2014, 9 (9), pp.e108514. ⟨10.1371/journal.pone.0108514⟩ Article dans une revue hal-04843363v1
Assessing the Efficacy of Nano- and Micro-Sized Magnetic Particles as Contrast Agents for MRI Cell Tracking Arthur Taylor,Anne Herrmann,Diana Moss,Violaine Sée,Karen Davieset al. PLoS ONE, 2014, 9 (6), pp.e100259. ⟨10.1371/journal.pone.0100259⟩ Article dans une revue hal-04843346v1
Tight Control of Hypoxia-inducible Factor-α Transient Dynamics Is Essential for Cell Survival in Hypoxia James Bagnall,Joseph Leedale,Sarah Taylor,David Spiller,Michael R.H. Whiteet al. Journal of Biological Chemistry, 2014, 289 (9), pp.5549-5564. ⟨10.1074/jbc.M113.500405⟩ Article dans une revue hal-04843370v1
Quantum Dots Do Not Affect the Behaviour of Mouse Embryonic Stem Cells and Kidney Stem Cells and Are Suitable for Short-Term Tracking Aleksandra Rak-Raszewska,Marco Marcello,Simon Kenny,David Edgar,Violaine Séeet al. PLoS ONE, 2012, 7 (3), pp.e32650. ⟨10.1371/journal.pone.0032650⟩ Article dans une revue hal-04843395v1
Exploitation of chick embryo environments to reprogram MYCN-amplified neuroblastoma cells to a benign phenotype, lacking detectable MYCN expression R Carter,D Mullassery,Violaine Sée,S Theocharatos,B Pizeret al. Oncogenesis, 2012, 1 (8), pp.e24-e24. ⟨10.1038/oncsis.2012.24⟩ Article dans une revue hal-04843372v1
p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma D Meley,D Spiller,M White,H Mcdowell,B Pizeret al. Cell Death and Disease, 2010, 1 (5), pp.e41-e41. ⟨10.1038/cddis.2010.16⟩ Article dans une revue hal-04843406v1
Highly Stable Dextran-Coated Quantum Dots for Biomolecular Detection and Cellular Imaging Robert Wilson,David Spiller,Alison Beckett,Ian Prior,Violaine Sée Chemistry of Materials, 2010, 22 (23), pp.6361-6369. ⟨10.1021/cm1023635⟩ Article dans une revue hal-04843379v1
Inflicting Controlled Nonthermal Damage to Subcellular Structures by Laser-Activated Gold Nanoparticles Željka Krpetić,Paola Nativo,Violaine Sée,Ian Prior,Mathias Brustet al. Nano Letters, 2010, 10 (11), pp.4549-4554. ⟨10.1021/nl103142t⟩ Article dans une revue hal-04843382v1
Self-association of Calcium-binding Protein S100A4 and Metastasis Thamir Ismail,Shu Zhang,David Fernig,Stephane Gross,Marisa Martin-Fernandezet al. Journal of Biological Chemistry, 2010, 285 (2), pp.914-922. ⟨10.1074/jbc.M109.010892⟩ Article dans une revue hal-04843388v1
Gold nanoparticles delivery in mammalian live cells: a critical review Raphaël Lévy,Umbreen Shaheen,Yann Cesbron,Violaine Sée Nano Reviews, 2010, 1 (1), pp.4889. ⟨10.3402/nano.v1i0.4889⟩ Article dans une revue hal-04850850v1
VEGF Stimulates RCAN1.4 Expression in Endothelial Cells via a Pathway Requiring Ca2+/Calcineurin and Protein Kinase C-δ Katherine Holmes,Elinor Chapman,Violaine Sée,Michael Cross PLoS ONE, 2010, 5 (7), pp.e11435. ⟨10.1371/journal.pone.0011435⟩ Article dans une revue hal-04843403v1
Pulsatile Stimulation Determines Timing and Specificity of NF-κB-Dependent Transcription Louise Ashall,Caroline Horton,David Nelson,Pawel Paszek,Claire Harperet al. Science, 2009, 324 (5924), pp.242-246. ⟨10.1126/science.1164860⟩ Article dans une revue hal-04850796v1
C2‐ceramide and reactive oxygen species inhibit pituitary adenylate cyclase activating polypeptide (PACAP)‐induced cyclic‐AMP‐dependent signalling pathway Violaine Sée,B. Koch,J. Loeffler Journal of Neurochemistry, 2008, 76 (3), pp.778-788. ⟨10.1046/j.1471-4159.2001.00106.x⟩ Article dans une revue hal-04850841v1
HP1α guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation Irina Panteleeva,Stéphanie Boutillier,Violaine Sée,Dave Spiller,Caroline Rouauxet al. EMBO Journal, 2007, 26 (15), pp.3616-3628. ⟨10.1038/sj.emboj.7601789⟩ Article dans une revue hal-04850797v1
Antibody-bound β-amyloid precursor protein stimulates the production of tumor necrosis factor-α and monocyte chemoattractant protein-1 by cortical neurons Corinne Mbebi,Jose-Luis González de Aguilar,Violaine Sée,Luc Dupuis,Nelly Frossardet al. Neurobiology of Disease, 2005, 19 (1-2), pp.129-141. ⟨10.1016/j.nbd.2004.11.010⟩ Article dans une revue istex hal-04850802v1
Oscillations in transcription factor dynamics: a new way to control gene expression D.E. Nelson,Violaine Sée,G. Nelson,M.R.H. White Biochemical Society Transactions, 2004, 32 (6), pp.1090-1092. ⟨10.1042/BST0321090⟩ Article dans une revue hal-04850812v1
Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression D. Nelson,A. Ihekwaba,M. Elliott,J. Johnson,C. Gibneyet al. Science, 2004, 306 (5696), pp.704-708. ⟨10.1126/science.1099962⟩ Article dans une revue hal-04850820v1
Calcium-dependent regulation of the cell cycle via a novel MAPK–NF-κB pathway in Swiss 3T3 cells Violaine Sée,Nina K.M. Rajala,David Spiller,Michael R.H. White Journal of Cell Biology, 2004, 166 (5), pp.661-672. ⟨10.1083/jcb.200402136⟩ Article dans une revue hal-04850828v1
Amyloid Precursor Protein Family-induced Neuronal Death Is Mediated by Impairment of the Neuroprotective Calcium/Calmodulin Protein Kinase IV-dependent Signaling Pathway Corinne Mbebi,Violaine Sée,Luc Mercken,Laurent Pradier,Ulrike Mülleret al. Journal of Biological Chemistry, 2002, 277 (23), pp.20979-20990. ⟨10.1074/jbc.M107948200⟩ Article dans une revue hal-04850831v1
Oxidative Stress Induces Neuronal Death by Recruiting a Protease and Phosphatase-gated Mechanism Violaine Sée,Jean-Philippe Loeffler Journal of Biological Chemistry, 2001, 276 (37), pp.35049-35059. ⟨10.1074/jbc.M104988200⟩ Article dans une revue hal-04850836v1
Calcium/calmodulin‐dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons Violaine Sée,Anne-Laurence Boutillier,Haruhiko Bito,Jean-Philippe Loeffler FASEB Journal, 2001, 15 (1), pp.134-144. ⟨10.1096/fj.00-0106com⟩ Article dans une revue hal-04850838v1

Chapitre d'ouvrage (2)

Live Imaging of Cell Invasion Using a Multicellular Spheroid Model and Light-Sheet Microscopy Marco Marcello,Rosalie Richards,David Mason,Violaine Sée Multi-Parametric Live Cell Microscopy of 3D Tissue Models, 1035, Springer International Publishing, pp.155-161, 2017, Advances in Experimental Medicine and Biology, ⟨10.1007/978-3-319-67358-5_11⟩ Chapitre d'ouvrage hal-04843325v1
The Chorioallantoic Membrane of the Chick Embryo to Assess Tumor Formation and Metastasis Anne Herrmann,Diana Moss,Violaine Sée Tumor Angiogenesis Assays, 1464, Springer New York, pp.97-105, 2016, Methods in Molecular Biology, ⟨10.1007/978-1-4939-3999-2_9⟩ Chapitre d'ouvrage hal-04843329v1