Xiaojing Cong

Publications

Article dans une revue (16)

A photoswitchable positive allosteric modulator to control the activation of the metabotropic glutamate receptor 5 by light Anaëlle Dumazer,Roser Borras-Tuduri,Iona Truong,Xiaojing Cong,Fanny Malhaireet al. Biochemical Pharmacology, 2025, 240, pp.117065. ⟨10.1016/j.bcp.2025.117065⟩ Article dans une revue hal-05140566v1
Conformational dynamics underlying atypical chemokine receptor 3 activation Omolade Otun,Christelle Aljamous,Elise Del Nero,Marta Arimont-Segura,Reggie Bosmaet al. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (30), pp.e2404000121. ⟨10.1073/pnas.2404000121⟩ Article dans une revue hal-04731883v1
Biased activation of the vasopressin V2 receptor probed by NMR, paramagnetic ligands, and molecular dynamics simulations Aurelien Fouillen,Pierre Couvineau,Gérald Gaibelet,Stéphanie Riché,Hélène Orcelet al. Computational and Structural Biotechnology Journal, 2024, 23, pp.3784-3799. ⟨10.1016/j.csbj.2024.10.039⟩ Article dans une revue hal-03756232v2
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition Sarah Erlandson,Shaun Rawson,James Osei-Owusu,Kelly Brock,Xinyue Liuet al. Nature Chemical Biology, 2023, 19 (8), pp.1013-1021. ⟨10.1038/s41589-023-01321-6⟩ Article dans une revue hal-04284543v1
Large-Scale G Protein-Coupled Olfactory Receptor–Ligand Pairing Xiaojing Cong,Wenwen Ren,Jody Pacalon,Rui Xu,Lun Xuet al. ACS Central Science, 2022, 8 (3), pp.379-387. ⟨10.1021/acscentsci.1c01495⟩ Article dans une revue hal-05505442v1
Structure of the vasopressin hormone–V2 receptor–β-arrestin1 ternary complex Julien Bous,Aurélien Fouillen,Hélène Orcel,Stefano Trapani,Xiaojing Conget al. Science Advances , 2022, 8 (35), pp.eabo7761. ⟨10.1126/sciadv.abo7761⟩ Article dans une revue hal-03790728v1
The Third Extracellular Loop of Mammalian Odorant Receptors Is Involved in Ligand Binding Tammy Shim,Jody Pacalon,Won-Cheol Kim,Xiaojing Cong,Jérémie Topinet al. International Journal of Molecular Sciences, 2022, 23 (20), pp.12501. ⟨10.3390/ijms232012501⟩ Article dans une revue hal-04712540v1
Interactions among key residues regulate mammalian odorant receptor trafficking Rui Xu,Xiaojing Cong,Qian Zheng,Lun Xu,Mengjue Niet al. FASEB Journal, 2022, 36 (7), pp.e22384. ⟨10.1096/fj.202200116RR⟩ Article dans une revue hal-04724118v1
Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins Paul Lambey,Omolade Otun,Xiaojing Cong,François Hoh,Luc Brunelet al. eLife, 2022, 11, pp.e72555. ⟨10.7554/eLife.72555⟩ Article dans une revue hal-03754372v1
Discovery and mechanism of action of small molecule inhibitors of ceramidases Robert Healey,Essa Saied,Xiaojing Cong,Gergely Karsai,Ludovic Gabellieret al. Angewandte Chemie International Edition, 2022, 61 (2), pp.e202109967. ⟨10.1002/anie.202109967⟩ Article dans une revue hal-03406152v1
Extracellular loop 2 of G protein-coupled olfactory receptors is critical for odorant recognition Yiqun Yu,Zhenjie Ma,Jody Pacalon,Lun Xu,Weihao Liet al. Journal of Biological Chemistry, 2022, 298 (9), pp.102331. ⟨10.1016/j.jbc.2022.102331⟩ Article dans une revue hal-03749290v1
An automated platform for structural analysis of membrane proteins through serial crystallography Robert Healey,Shibom Basu,Anne-Sophie Humm,Cedric Leyrat,Xiaojing Conget al. Cell Reports Methods, 2021, 1 (6), pp.100102. ⟨10.1016/j.crmeth.2021.100102⟩ Article dans une revue hal-03414080v1
Molecular insights into the biased signaling mechanism of the μ-opioid receptor Xiaojing Cong,Damien Maurel,Héléne Démèné,Ieva Vasiliauskaité-Brooks,Joanna Hagelbergeret al. Molecular Cell, In press, 81 (20), pp.4165-4175.e6. ⟨10.1016/j.molcel.2021.07.033⟩ Article dans une revue hal-03331072v1
Allosteric Modulation Mechanism of the mGluR 5 Transmembrane Domain Xiaojing Cong,Jean-Baptiste Chéron,Jérôme Golebiowski,Serge Antonczak,Sébastien Fiorucci Journal of Chemical Information and Modeling, 2019, ⟨10.1021/acs.jcim.9b00045⟩ Article dans une revue hal-02137256v1
Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts Xiaojing Cong,Qian Zheng,Wenwen Ren,Jean-Baptiste Chéron,Sébastien Fiorucciet al. Journal of Biological Chemistry, 2019, 294 (17), pp.6762-6771. ⟨10.1074/jbc.RA118.006483⟩ Article dans une revue hal-02545194v1
Activation Dynamics of the Neurotensin G Protein-Coupled Receptor 1 Xiaojing Cong,Sébastien Fiorucci,Jérôme Golebiowski Journal of Chemical Theory and Computation, 2018, 14 (8), pp.4467-4473. ⟨10.1021/acs.jctc.8b00216⟩ Article dans une revue hal-02545198v1

Pré-publication, Document de travail (1)

Conformational dynamics underlying Atypical Chemokine Receptor 3 activation Omolade Otun,Christelle Aljamous,Elise Del Nero,Marta Arimont-Segura,Reggie Bosmaet al. 2023 Pré-publication, Document de travail hal-04284417v1

Poster de conférence (1)

The Functional Role of the Third Extracellular Loop of Mammalian Odorant Receptors in Ligand Binding Tammy Shim,Jody Pacalon,Woncheol Kim,Xiaojing Cong,Jérémie Topinet al. XLVth Annual Meeting of the Association for Chemoreception Sciences, AChemS, Apr 2023, Bonita Springs (Floride), United States. Oxford University Press, Chemical Senses, 48, pp.121, bjad029.279, 2024 Poster de conférence hal-04730776v1

Communication dans un congrès (1)

Mechanism of GPCR activation triggered by ligands, mutations and protonation Xiaojing Cong,Jean-Baptiste Chéron,Serge Antonczak,Sébastien Fiorucci,Jerôme Golebiowski GGMM2019, GGMM, Apr 2019, Nice, France Communication dans un congrès hal-02546262v1