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Structure and Catalytic Mechanism of Radical SAM Methylases
Tu-Quynh Nguyen
,
Yvain Nicolet
Journal articles
hal-03853118v1
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Oxygen-sensitive metalloprotein structure determination by cryo-electron microscopy
Mickaël Cherrier
,
Xavier Vernède
,
Daphna Fenel
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Lydie Martin
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Benoit Arragain
et al.
Journal articles
hal-03615151v1
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Iron–sulfur clusters as inhibitors and catalysts of viral replication
Kourosh Honarmand Ebrahimi
,
Simone Ciofi-Baffoni
,
Peter-Leon Hagedoorn
,
Yvain Nicolet
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Nick Le Brun
et al.
Journal articles
hal-03590147v1
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Characterization of a Radical SAM Oxygenase for the Ether Crosslinking in Darobactin Biosynthesis
Hai Nguyen
,
I Dewa Made Kresna
,
Nils Böhringer
,
Jeremie Ruel
,
Eugenio de La Mora
et al.
Journal articles
hal-03807959v1
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L-tyrosine-bound ThiH structure reveals C–C bond break differences within radical SAM aromatic amino acid lyases
Patricia Amara
,
Claire Saragaglia
,
Jean-Marie Mouesca
,
Lydie Martin
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Yvain Nicolet
et al.
Journal articles
hal-03669800v1
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An Unexpected P-Cluster like Intermediate En Route to the Nitrogenase FeMo-co
Leon Jenner
,
Mickaël Cherrier
,
Patricia Amara
,
Luis Rubio
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Yvain Nicolet
et al.
Journal articles
hal-03161940v1
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Radical SAM Enzymes and Metallocofactor Assembly: A Structural Point of View
Yvain Nicolet
,
Mickael Cherrier
,
Patricia Amara
Journal articles
hal-03454299v1
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Methods to Screen for Radical SAM Enzyme Crystallization Conditions
Lydie Martin
,
Xavier Vernède
,
Yvain Nicolet
Journal articles
hal-03328451v1
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New developments in RiPP discovery, enzymology and engineering
Manuel Montalbán-López
,
Thomas Scott
,
Sangeetha Ramesh
,
Imran Rahman
,
Auke van Heel
et al.
Journal articles
hal-02947402v1
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Crystal structure of the [FeFe]-Hydrogenase maturase HydE bound to complex-B
Roman Rohac
,
Lydie Martin
,
Liang Liu
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Debashis Basu
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Lizhi Tao
et al.
Journal articles
hal-03328547v1
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High-resolution structure of a modular hyperthermostable endo-β-1,4-mannanase from Thermotoga petrophila: The ancillary immunoglobulin-like module is a thermostabilizing domain
Viviam da Silva
,
Aline Cabral
,
Marcia Sperança
,
Fabio Squina
,
João Renato C Muniz
et al.
Journal articles
hal-02556971v1
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A way to thioacetate esters compatible with non-oxidative prebiotic conditions
Naoual Leqraa
,
Yvain Nicolet
,
Anne Milet
,
Yannick Vallée
Journal articles
hal-02934448v1
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Structure–function relationships of radical SAM enzymes
Yvain Nicolet
Journal articles
hal-02547495v1
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Structural insights into the mechanism of the radical SAM carbide synthase NifB, a key nitrogenase cofactor maturating enzyme
Ana Sosa Fajardo
,
Pierre Legrand
,
Lucía Payá-Tormo
,
Lydie Martin
,
Maria Teresa Pellicer Martinez
et al.
Journal articles
hal-02775951v1
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How [Fe]-hydrogenase metabolizes dihydrogen
Yvain Nicolet
Journal articles
hal-02166639v1
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Human viperin catalyzes the modification of GPP and FPP potentially affecting cholesterol synthesis
Pavel Mikulecky
,
Elena Andreeva
,
Patricia Amara
,
Winfried Weissenhorn
,
Yvain Nicolet
et al.
Journal articles
hal-01677120v1
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1,2-diol dehydration by the radical SAM enzyme AprD4 – a matter of proton circulation and substrate flexibility
Qi Liu
,
Patricia Amara
,
Jean-Marie Mouesca
,
Xinjian Ji
,
Oriane Renoux
et al.
Journal articles
hal-01685058v1
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Radical S -Adenosyl- l -methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical •CO 2 – Migration
Patricia Amara
,
Jean-Marie Mouesca
,
Maxime Bella
,
Lydie Martin
,
Claire Saragaglia
et al.
Journal articles
hal-02008403v1
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CO and CN- syntheses by [FeFe]-hydrogenase maturase HydG are catalytically differentiated events.
Adrien Pagnier
,
Lydie Martin
,
Laura Zeppieri
,
Yvain Nicolet
,
Juan-Carlos Fontecilla-Camps
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (1), pp.104-9
Journal articles
hal-01252697v1
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Fine-tuning of a radical-based reaction by radical S-adenosyl-L-methionine tryptophan lyase
G. Sicoli
,
J.-M. Mouesca
,
Laura Zeppieri
,
Patricia Amara
,
Lydie Martin
et al.
Journal articles
hal-01297885v1
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Carbon-sulfur bond-forming reaction catalysed by the radical SAM enzyme HydE.
Roman Rohac
,
Patricia Amara
,
Alhosna Benjdia
,
Lydie Martin
,
Pauline Ruffié
et al.
Journal articles
hal-01341083v1
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IscS from Archaeoglobus fulgidus has no desulfurase activity but may provide a cysteine ligand for [Fe2S2] cluster assembly.
Adrien Pagnier
,
Yvain Nicolet
,
Juan-Carlos Fontecilla-Camps
BBA - Biochimica et Biophysica Acta, 2015, 1853 (6), pp.1457-1463
Journal articles
hal-01119798v1
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The crystal structure of the global anaerobic transcriptional regulator FNR explains its extremely fine-tuned monomer-dimer equilibrium
Anne Volbeda
,
Claudine Darnault
,
O. Renoux
,
Yvain Nicolet
,
Juan-Carlos Fontecilla-Camps
et al.
Journal articles
hal-01240354v1
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Crystal structure of HydG from Carboxydothermus hydrogenoformans: a trifunctional [FeFe]-hydrogenase maturase.
Yvain Nicolet
,
Adrien Pagnier
,
Laura Zeppieri
,
Lydie Martin
,
Patricia Amara
et al.
ChemBioChem, 2015, 16 (3), pp.397-402
Journal articles
hal-01166126v1
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Tryptophan Lyase (NosL): Mechanistic Insights from Substrate Analogues and Mutagenesis.
Dhananjay M Bhandari
,
Hui Xu
,
Yvain Nicolet
,
Juan-Carlos Fontecilla-Camps
,
Tadhg P Begley
et al.
Biochemistry, 2015, 54 (31), pp.4767-9
Journal articles
hal-01191593v1
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Crystal structure of tryptophan lyase (NosL): evidence for radical formation at the amino group of tryptophan.
Yvain Nicolet
,
Laura Zeppieri
,
Patricia Amara
,
Juan-Carlos Fontecilla-Camps
Angewandte Chemie International Edition, 2014, 53 (44), pp.11840-4
Journal articles
hal-01119795v1
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X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters
Yvain Nicolet
,
Roman Rohac
,
Lydie Martin
,
Juan-Carlos Fontecilla-Camps
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (18), pp.7188 - 7192. ⟨10.1073/pnas.1302388110⟩
Journal articles
hal-01664850v1
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Crystal structure and functional studies of an unusual l -cysteine desulfurase from Archaeoglobus fulgidus
Yasuaki Yamanaka
,
Laura Zeppieri
,
Yvain Nicolet
,
Elodie N Marinoni
,
Jaim S de Oliveira
et al.
Journal articles
hal-01666076v1
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Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase.
Florian Nachon
,
Eugénie Carletti
,
Cyril Ronco
,
Marie Trovaslet
,
Yvain Nicolet
et al.
Journal articles
hal-00996550v1
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Reactibodies generated by kinetic selection couple chemical reactivity with faborable protein dynamics.
I.V. Smirnov
,
E. Carletti
,
I.N. Kurkova
,
F. Nachon
,
Y. Nicolet
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108, pp.15954-15959
Journal articles
hal-00637416v1
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Further Characterization of the [FeFe]-Hydrogenase Maturase HydG
Cécile Tron
,
Mickael V Cherrier
,
Patricia Amara
,
Lydie Martin
,
Martin Fauth
et al.
Journal articles
hal-01140285v1
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X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger
Florian Nachon
,
Eugenie Carletti
,
Marielle Wandhammer
,
Yvain Nicolet
,
Lawrence M Schopfer
et al.
Journal articles
hal-00560692v1
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A glycyl free radical as the precursor in the synthesis of carbon monoxide and cyanide by the [FeFe]-hydrogenase maturase HydG
Yvain Nicolet
,
Lydie Martin
,
Cécile Tron
,
Juan-Carlos Fontecilla-Camps
Journal articles
hal-01235598v1
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Maturation of [FeFe]-hydrogenases: Structures and mechanisms
Yvain Nicolet
,
Juan-Carlos Fontecilla-Camps
,
Marc Fontecave
Journal articles
hal-01145486v1
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Structure-function relationships of anaerobic gas-processing metalloenzymes
Juan-Carlos Fontecilla-Camps
,
Patricia Amara
,
Christine Cavazza
,
Yvain Nicolet
,
Anne Volbeda
et al.
Journal articles
cea-00909652v1
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The role of the maturase HydG in [FeFe]-hydrogenase active site synthesis and assembly
Eric Pilet
,
Yvain Nicolet
,
Carole Mathevon
,
Thierry Douki
,
Juan-Carlos Fontecilla-Camps
et al.
FEBS Letters, 2009, 583 (3), pp.506-511
Journal articles
hal-00371635v1
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Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun
Eugénie Carletti
,
Nadine Aurbek
,
Emilie Gillon
,
Mélanie Loiodice
,
Yvain Nicolet
et al.
Journal articles
hal-00479152v1
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X-ray structure of the [Fe-Fe]-hydrogenase maturase hydE from thermotoga maritima.
Yvain Nicolet
,
Jon K. Ruback
,
Matthew C. Posewitz
,
Patricia Amara
,
Carole Mathevon
et al.
Journal of Biological Chemistry, 2008, 283 (27), pp.18861-18872
Journal articles
hal-00377680v1
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Characterization of the DNA repair spore photoproduct lyase enzyme from Clostridium acetobutylicum: A radical-SAM enzyme.
Alexia Chandor
,
Thierry Douki
,
Didier Gasparutto
,
Serge Gambarelli
,
Yiannis Sanakis
et al.
Comptes Rendus. Chimie, 2007, 10, pp.756-765
Journal articles
hal-00377642v2
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Structural Changes of Escherichia coli Ferric Uptake Regulator during Metal-dependent Dimerization and Activation Explored by NMR and X-ray Crystallography
Ludovic Pecqueur
,
Benoit d'Autreaux
,
Jérôme Dupuy
,
Yvain Nicolet
,
Lilian Jacquamet
et al.
Journal articles
hal-02975695v1
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