Yvan De Launoit

Publications

Article dans une revue (48)

Targeting ATF6α Attenuates UVB ‐Induced Senescence and Improves Skin Homeostasis by Regulating IL8 Expression Joëlle Giroud,Pauline Delvaux,Laura Carlier,Clémentine de Schutter,Nathalie Martinet al. Aging Cell, 2025, 24 (6), pp.e70024. ⟨10.1111/acel.70024⟩ Article dans une revue hal-05103261v1
Cell Senescence and the DNA Single-Strand Break Damage Repair Pathway Parvathy A Sarma,Corinne Abbadie,Yvan de Launoit,Fabrizio Cleri DNA, 2024, 4 (4), pp.530-552. ⟨10.3390/dna4040036⟩ Article dans une revue (article de synthèse) hal-04828409v1
Tri des cellules sénescentes par cytométrie en flux Élodie Rodzinski,Nathalie Martin,Raphael Rouget,Adrien Pioger,Vanessa Dehennautet al. Médecine/Sciences, 2024, 40 (3), pp.275-282. ⟨10.1051/medsci/2024011⟩ Article dans une revue hal-04774057v1
Tri des cellules sénescentes par cytométrie en flux Élodie Rodzinski,Nathalie Martin,Raphael Rouget,Adrien Pioger,Vanessa Dehennautet al. Médecine/Sciences, 2024, 40 (3), pp.275-282. ⟨10.1051/medsci/2024011⟩ Article dans une revue hal-04518057v1
Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor Anthony Turpin,Carine Delliaux,Pauline Parent,Hortense Chevalier,Carmen Escudero-Iriarteet al. British Journal of Cancer, 2023, ⟨10.1038/s41416-023-02449-x⟩ Article dans une revue hal-04308764v1
Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor Anthony Turpin,Carine Delliaux,Pauline Parent,Hortense Chevalier,Carmen Escudero-Iriarteet al. British Journal of Cancer, 2023, 129 (12), pp.1903-1914. ⟨10.1038/s41416-023-02449-x⟩ Article dans une revue hal-04774153v1
Flow Cytometry-based Method for Efficient Sorting of Senescent Cells Erwan Goy,Nathalie Martin,Claire Drullion,Laure Saas,Olivier Molendi-Costeet al. Bio-protocol , 2023, 13 (7), pp.e4612. ⟨10.21769/BioProtoc.4612⟩ Article dans une revue hal-04774160v1
Flow Cytometry-based Method for Efficient Sorting of Senescent Cells Erwan Goy,Nathalie Martin,Claire Drullion,Laure Saas,Olivier Molendi-Costeet al. Bio-protocol , 2023, 13 (7), ⟨10.21769/BioProtoc.4612⟩ Article dans une revue hal-04268798v1
Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer Leslie Duplaquet,Martin Figeac,Frédéric Leprêtre,Charline Frandemiche,Céline Villenetet al. Molecular Cancer Therapeutics, 2019, 18 (6), pp.1137-1148. ⟨10.1158/1535-7163.MCT-18-0582⟩ Article dans une revue hal-04540714v1
Aberrant up-regulation of iNOS/NO system is correlated with an increased abundance of Foxp3+ cells and reduced effector/memory cell markers expression during colorectal cancer: immunomodulatory effects of cetuximab combined with chemotherapy Sarra Benkhelifa,Hayet Rafa,Said Belhadef,Hayat Ait-Kaci,Oussama Medjeberet al. Inflammopharmacology, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩ Article dans une revue hal-02391591v1
TMPRSS2:ERG gene fusion expression regulates bone markers and enhances the osteoblastic phenotype of prostate cancer bone metastases Carine Delliaux,Tian Tian,Mathilde Bouchet,Anais Fradet,Nathalie Vanpouilleet al. Cancer Letters, 2018, 438, pp.32 - 43. ⟨10.1016/j.canlet.2018.08.027⟩ Article dans une revue hal-03060052v1
ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis Mandy Dumortier,Franck Ladam,Isabelle Damour,Sophie Vacher,Ivan Biecheet al. Breast Cancer Research, 2018, 20 (1), pp.73. ⟨10.1186/s13058-018-0992-0⟩ Article dans une revue hal-02391607v1
All-Trans Retinoic Acid Modulates TLR4/NF- κ B Signaling Pathway Targeting TNF- α and Nitric Oxide Synthase 2 Expression in Colonic Mucosa during Ulcerative Colitis and Colitis Associated Cancer Hayet Rafa,Sarra Benkhelifa,Sonia Aityounes,Houria Saoula,Said Belhadefet al. Mediators of Inflammation, 2017, 2017, pp.7353252. ⟨10.1155/2017/7353252⟩ Article dans une revue hal-02391613v1
TMPRSS2-ERG fusion promotes prostate cancer metastases in bone Rachel Deplus,Carine Delliaux,Nathalie Marchand,Anne Flourens,Nathalie Vanpouilleet al. Oncotarget, 2017, 8 (7), pp.11827-11840. ⟨10.18632/oncotarget.14399⟩ Article dans une revue hal-02391621v1
Effect of Nasopharyngeal Carcinoma-Derived Exosomes on Human Regulatory T Cells Dhafer Mrizak,Nathalie Martin,Clément Barjon,Anne-Sophie Jimenez-Pailhes,Rami Mustaphaet al. JNCI: Journal of the National Cancer Institute, 2015, 107 (1), pp.363. ⟨10.1093/jnci/dju363⟩ Article dans une revue hal-02395739v1
TRP channel–associated factors are a novel protein family that regulates TRPM8 trafficking and activity Dimitra Gkika,Loic Lemonnier,George Shapovalov,Dmitri Gordienko,Céline Pouxet al. Journal of Cell Biology, 2015, 208 (1), pp.89-107. ⟨10.1083/jcb.201402076⟩ Article dans une revue hal-01111024v1
The obesity-associated transcription factor ETV5 modulates circulating glucocorticoids Ruth Gutierrez-Aguilar,Abigail Thompson,Nathalie Marchand,Patrick Dumont,Stephen C. Woodset al. Physiology & behavior, 2015, 150, pp.38 - 42. ⟨10.1016/j.physbeh.2015.03.027⟩ Article dans une revue hal-03059809v1
PEA3 transcription factors are downstream effectors of Met signaling involved in migration and invasiveness of Met-addicted tumor cells Zoulika Kherrouche,Didier Monté,Elisabeth Werkmeister,Luc Stoven,Yvan de Launoitet al. Molecular Oncology, 2015, 9 (9), pp.1852 - 1867. ⟨10.1016/j.molonc.2015.07.001⟩ Article dans une revue hal-03059808v1
PEA3 transcription factors are downstream effectors of Met signaling involved in migration and invasiveness of Met-addicted tumor cells Zoulika Kherrouche,Didier Monte,Elisabeth Werkmeister,Luc Stoven,Yvan de Launoitet al. Molecular Oncology, 2015, 9 (9), pp.1852-1867. ⟨10.1016/j.molonc.2015.07.001⟩ Article dans une revue hal-02392146v1
TRP channel–associated factors are a novel protein family that regulates TRPM8 trafficking and activity Dimitra Gkika,Loic Lemonnier,George Shapovalov,Dmitri Gordienko,Céline Pouxet al. Journal of Cell Biology, 2015, 208 (1), pp.89-107. ⟨10.1083/jcb.201402076⟩ Article dans une revue hal-04321398v1
Epstein-Barr virus infection induces an increase of T regulatory type 1 cells in Hodgkin lymphoma patients Olivier Moralès,Dhafer Mrizak,Violaine François,Rami Mustapha,Céline Mirouxet al. British Journal of Haematology, 2014, 166 (6), pp.875-890. ⟨10.1111/bjh.12980⟩ Article dans une revue hal-02395755v1
Regulation of DNA Methylation Patterns by CK2-Mediated Phosphorylation of Dnmt3a Rachel Deplus,Loïc Blanchon,Arumugam Rajavelu,Abdelhalim Boukaba,Matthieu Defranceet al. Cell Reports, 2014, 8 (3), pp.743 - 753. ⟨10.1016/j.celrep.2014.06.048⟩ Article dans une revue hal-01918737v1
IL-23/IL-17A Axis Correlates with the Nitric Oxide Pathway in Inflammatory Bowel Disease: Immunomodulatory Effect of Retinoic Acid Hayet Rafa,Houria Saoula,Mourad Belkhelfa,Oussama Medjeber,Imene Soufliet al. Journal of Interferon and Cytokine Research, 2013, 33 (7), pp.355-368. ⟨10.1089/jir.2012.0063⟩ Article dans une revue hal-02395835v1
Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Franck Ladam,Isabelle Damour,Patrick Dumont,Zoulika Kherrouche,Yvan de Launoitet al. Molecular Cancer Research, 2013, 11 (11), pp.1412-1424. ⟨10.1158/1541-7786.MCR-13-0229⟩ Article dans une revue hal-02395816v1
PLA2R1 kills cancer cells by inducing mitochondrial stress Arnaud Augert,David Vindrieux,Christophe Girard,Benjamin Le Calvé,Baptiste Graset al. Free Radical Biology and Medicine, 2013, 65, pp.969-977. ⟨10.1016/j.freeradbiomed.2013.08.177⟩ Article dans une revue istex hal-02395811v1
The Mediator complex subunit MED25 is targeted by the N-terminal transactivation domain of the PEA3 group members Alexis Verger,Jean-Luc Baert,Kathye Verreman,Frédérique Dewitte,Elisabeth Ferreiraet al. Nucleic Acids Research, 2013, 41 (9), pp.4847-4859. ⟨10.1093/nar/gkt199⟩ Article dans une revue hal-02111611v1
Overexpression of Regulatory T Cells Type 1 (Tr1) Specific Markers in a Patient with HCV-Induced Hepatocellular Carcinoma Laurissa Ouaguia,Olivier Morales,Dhafer Mrizak,Khaldoun Ghazal,Emmanuel Boleslawskiet al. International Scholarly Research Notices, 2013, 2013, pp.928485. ⟨10.1155/2013/928485⟩ Article dans une revue hal-03059986v1
PLA2R1 Mediates Tumor Suppression by Activating JAK2 David Vindrieux,Arnaud Augert,Christophe Girard,Delphine Gitenay,Helene Lallet-Daheret al. Cancer Research, 2013, 73 (20), pp.6334-6345. ⟨10.1158/0008-5472.CAN-13-0318⟩ Article dans une revue hal-02395807v1
Identification of novel TMPRSS2:ERG mechanisms in prostate cancer metastasis: involvement of MMP9 and PLXNA2 Anthony Turpin,Carine Delliaux,Pauline Parent,Hortense Chevalier,Carmen Escudero-Iriarteet al. Oncogene, 2013, 33, pp.2204 - 2214. ⟨10.1038/onc.2013.176⟩ Article dans une revue hal-03059981v1
Corticosteroids Do Not Reverse the Inhibitory Effect of Cyclosporine on Regulatory T-Cell Activity in Contrast to Mycophenolate Mofetil C. Miroux,O. Morales,L. Ouaguia,L. Aoudjehane,E. Boleslawskiet al. Transplantation Proceedings, 2012, 44 (9), pp.2834-2839. ⟨10.1016/j.transproceed.2012.09.091⟩ Article dans une revue istex hal-02395841v1
EBV Latency II-derived Peptides Induce A Specific CD4+ Cytotoxic T-cell Activity and Not A CD4+ Regulatory T-cell Response Olivier Moralès,Stéphane Depil,Dhafer Mrizak,Nathalie Martin,Papa Alioune Ndouret al. Journal of Immunotherapy, 2012, 35 (3), pp.254-266. ⟨10.1097/CJI.0b013e31824d72c5⟩ Article dans une revue hal-03059998v1
Altered Expression of the Poly(ADP-Ribosyl)ation Enzymes in Uveal Melanoma and Regulation of PARG Gene Expression by the Transcription Factor ERM Vanessa Molloy-Simard,Jean-François St-Laurent,François Vigneault,Manon Gaudreault,Natasha Dargiset al. Investigative Ophthalmology & Visual Science, 2012, 53 (10), pp.6219. ⟨10.1167/iovs.11-8853⟩ Article dans une revue hal-03059995v1
Anti-apoptotic Role of Caspase-cleaved GAB1 Adaptor Protein in Hepatocyte Growth Factor/Scatter Factor-MET Receptor Protein Signaling Arnaud Le Goff,Zongling Ji,Bérénice Leclercq,Roland Bourette,Alexandra Mougelet al. Journal of Biological Chemistry, 2012, 287 (42), pp.35382-35396. ⟨10.1074/jbc.M112.409797⟩ Article dans une revue hal-03104091v1
Activation of a Helper and Not Regulatory Human CD4+ T Cell Response by Oncolytic H-1 Parvovirus Olivier Moralès,Audrey Richard,Nathalie Martin,Dhafer Mrizak,Magalie Sénéchalet al. PLoS ONE, 2012, 7 (2), pp.e32197. ⟨10.1371/journal.pone.0032197⟩ Article dans une revue hal-03059999v1
In vitro effects of cyclosporine A and tacrolimus on regulatory T-cell proliferation and function. Céline Miroux,Olivier Morales,Khaldoun Ghazal,Samia Ben Othman,Yvan de Launoitet al. Transplantation, 2012, 94 (2), pp.123-31. ⟨10.1097/TP.0b013e3182590d8f⟩ Article dans une revue hal-00785885v1
NMR structure of the human Mediator MED25 ACID domain. François Bontems,Alexis Verger,Frédérique Dewitte,Zoé Lens,Jean-Luc Baertet al. Journal of Structural Biology, 2011, 174 (1), pp.245-51. ⟨10.1016/j.jsb.2010.10.011⟩ Article dans une revue istex hal-00589014v1
The Coactivator Activator CoAA regulates PEA3 group member transcriptional activity Kathye Verreman,Jean-Luc Baert,Alexis Verger,Hervé Drobecq,Elisabeth Ferreiraet al. Biochemical Journal, 2011, 439 (3), pp.469-477. ⟨10.1042/BJ20110728⟩ Article dans une revue hal-00633602v1
Purification of SUMO-1 modified IκBα and complex formation with NF-κB Zoé Lens,Frédérique Dewitte,Carine van Lint,Yvan de Launoit,Vincent Villeretet al. Protein Expression and Purification, 2011, 80 (2), pp.211-216. ⟨10.1016/j.pep.2011.06.009⟩ Article dans une revue istex hal-03060002v1
Autocrine Induction of Invasive and Metastatic Phenotypes by the MIF-CXCR4 Axis in Drug-Resistant Human Colon Cancer Cells Anne-Frédérique Dessein,Laurence Stechly,Nicolas Jonckheere,Patrick Dumont,Didier Montéet al. Cancer Research, 2010, 70 (11), pp.4644-4654. ⟨10.1158/0008-5472.CAN-09-3828⟩ Article dans une revue hal-02106460v1
Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection. Sophie Reuse,Miriam Calao,Kabamba Kabeya,Allan Guiguen,Jean-Stéphane Gatotet al. PLoS ONE, 2009, 4 (6), pp.e6093. ⟨10.1371/journal.pone.0006093⟩ Article dans une revue hal-00464770v1
Senescent keratinocytes die by autophagic programmed cell death. Karo Gosselin,Emeric Deruy,Sébastien Martien,Chantal Vercamer,Fatima Boualiet al. American Journal of Pathology, 2009, 174 (2), pp.423-35. ⟨10.2353/ajpath.2009.080332⟩ Article dans une revue hal-01260066v1
Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells Karo Gosselin,Sébastien Martien,Albin Dr Pourtier,Chantal Vercamer,Peter Ostoichet al. Cancer Research, 2009, 69 (20), pp.7917-7925. ⟨10.1158/0008-5472.CAN-08-2510⟩ Article dans une revue hal-04488967v1
Regulation of ploidy and senescence by the AMPK-related kinase NUAK1 Nicolas Humbert,Naveenan Navaratnam,Arnaud Augert,Marco da Costa,Sébastien Martienet al. EMBO Journal, 2009, 29 (2), pp.376-386. ⟨10.1038/emboj.2009.342⟩ Article dans une revue hal-04277055v1
Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells Karo Gosselin,Sébastien Martien,Albin Pourtier,Chantal Vercamer,Peter Ostoichet al. Cancer Research, 2009, 69 (20), pp.7917-7925. ⟨10.1158/0008-5472.CAN-08-2510⟩ Article dans une revue hal-04277047v1
A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence Nicolas Humbert,Sébastien Martien,Arnaud Augert,Marco da Costa,Sébastien Mauenet al. Cancer Research, 2009, 69 (10), pp.4101-4106. ⟨10.1158/0008-5472.CAN-08-2864⟩ Article dans une revue hal-04277052v1
The M-type receptor PLA2R regulates senescence through the p53 pathway. Arnaud Augert,Christine Payré,Yvan de Launoit,Jesus Gil,Gérard Lambeauet al. EMBO Reports, 2009, 10 (3), pp.271-7. ⟨10.1038/embor.2008.255⟩ Article dans une revue hal-00417702v1
The Polycomb group protein EZH2 directly controls DNA methylation Emmanuelle Viré,Carmen Brenner,Rachel Deplus,Loïc Blanchon,Mario Fragaet al. Nature, 2006, 439 (7078), pp.871 - 874. ⟨10.1038/nature04431⟩ Article dans une revue istex hal-01918637v1
Expression patterns of the Ets transcription factors from the PEA3 group during early stages of mouse development Anne Chotteau-Lelievre,Pascal Dollé,Virginie Peronne,Laurent Coutte,Yvan de Launoitet al. Mechanisms of Development, 2001, 108 (1-2), pp.191-195. ⟨10.1016/s0925-4773(01)00480-4⟩ Article dans une revue istex hal-04093242v1

Pré-publication, Document de travail (1)

Cell senescence and the DNA single-strand break damage repair pathway Parvathy A Sarma,Corinne Abbadie,Yvan de Launoit,Fabrizio Cleri 2024 Pré-publication, Document de travail hal-04759695v1