zb

zeynep baharoglu

25
Documents

Présentation

EDUCATION AND TRAINING

2020 sept. HDR, Sorbonne Université, Paris

2008-2013 Post-doc in microbial genetics, Institut Pasteur

2005-2008 PhD thesis, Microbial Genetics, CGM-CNRS, Gif-sur-Yvette, UPMC

2005 Masters degree, Microbiology, University of Paris VII Diderot

2004 Undergraduate degree, Cell and Integrative Biology, University of Grenoble I, in exchange program with University of California Irvine

POSITIONS

2021 jan Chef de groupe "Bacterial responses to antimicrobial stress" at Unité Plasticité du génome bactérien - Institut Pasteur.

2017-present Chargée de recherche expert at Unité Plasticité du génome bactérien - Institut Pasteur

2014-2017 Chargée de recherche at Unité Plasticité du génome bactérien - Institut Pasteur.

2008-2013 Postdoctoral researcher. Unité Plasticité du génome bactérien - Institut Pasteur

2005-2008 Doctoral research fellow in Microbiology at Centre de Génétique Moléculaire – CNRS. Gif-sur-Yvette. Université Paris 6. Collaboration with University College London

SCIENTIFIC ACTIVITIES

19 publications (11 as first author, 3 articles as last author, 3 articles as corresponding author)

11 poster and 5 oral presentations in scientific meetings.

Publications

11
5
5
3
1
1
1

Publications

Image document

Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification

Louna Fruchard , Anamaria Babosan , Andre Carvalho , Manon Lang , Blaise Li et al.
eLife, 2025, 13, pp.RP96317. ⟨10.7554/eLife.96317.3⟩
Article dans une revue hal-05029047 v1
Image document

Exploring a unique class of flavoenzymes: Identification and biochemical characterization of ribosomal RNA dihydrouridine synthase

Sabrine Toubdji , Quentin Thullier , Lea-Marie Kilz , V. Marchand , Yifeng Yuan et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (32), pp.e2401981121. ⟨10.1073/pnas.2401981121⟩
Article dans une revue hal-04734945 v1
Image document

Measuring single-cell susceptibility to antibiotics within monoclonal bacterial populations

Lena Le Quellec , Andrey Aristov , Salomé Gutiérrez Ramos , Gabriel Amselem , Julia Bos et al.
PLoS ONE, 2024, 19 (8), pp.e0303630. ⟨10.1371/journal.pone.0303630⟩
Article dans une revue pasteur-04739933 v2
Image document

Systematic transcriptome analysis allows the identification of new type I and type II Toxin/Antitoxin systems located in the superintegron of Vibrio cholerae

Evelyne Krin , Zeynep Baharoglu , Odile Sismeiro , Hugo Varet , Jean-Yves Coppée et al.
Research in Microbiology, 2023, 174 (1-2), pp.103997. ⟨10.1016/j.resmic.2022.103997⟩
Article dans une revue pasteur-03889562 v1
Image document

RavA‐ViaA antibiotic response is linked to Cpx and Zra2 envelope stress systems in Vibrio cholerae

Evelyne Krin , André Carvalho , Manon Lang , Anamaria Babosan , Didier Mazel et al.
Microbiology Spectrum, 2023, 11 (6), pp.e01730-23. ⟨10.1128/spectrum.01730-23⟩
Article dans une revue pasteur-04260034 v1
Image document

Aminoglycoside uptake, stress, and potentiation in Gram-negative bacteria: new therapies with old molecules

Manon Lang , André Carvalho , Zeynep Baharoglu , Didier Mazel
Microbiology and Molecular Biology Reviews, 2023, ⟨10.1128/mmbr.00036-22⟩
Article dans une revue pasteur-04334889 v1
Image document

Non-essential tRNA and rRNA modifications impact the bacterial response to sub-MIC antibiotic stress

Anamaria Babosan , Louna Fruchard , Evelyne Krin , André Carvalho , Didier Mazel et al.
microLife, 2022, 3, pp.uqac019. ⟨10.1093/femsml/uqac019⟩
Article dans une revue pasteur-03897869 v2
Image document

A qnr-plasmid allows aminoglycosides to induce SOS in Escherichia coli

Anamaria Babosan , David Skurnik , Anaëlle Muggeo , Gerald Pier , Zeynep Baharoglu et al.
eLife, 2022, 11, ⟨10.7554/eLife.69511⟩
Article dans une revue hal-03919325 v1
Image document

Deficiency in cytosine DNA methylation leads to high chaperonin expression and tolerance to aminoglycosides in Vibrio cholerae

André Carvalho , Didier Mazel , Zeynep Baharoglu
PLoS Genetics, 2021, 17 (10), pp.e1009748. ⟨10.1371/journal.pgen.1009748⟩
Article dans une revue pasteur-03417428 v2
Image document

Interplay between Sublethal Aminoglycosides and Quorum Sensing: Consequences on Survival in V. cholerae

André Carvalho , Evelyne Krin , Chloé Korlowski , Didier Mazel , Zeynep Baharoglu
Cells, 2021, 10 (11), pp.3227. ⟨10.3390/cells10113227⟩
Article dans une revue pasteur-03443810 v2
Image document

Sleeping ribosomes: bacterial signaling triggers RaiA mediated persistence to aminoglycosides

Manon Lang , Evelyne Krin , Chloé Korlowski , Odile Sismeiro , Hugo Varet et al.
iScience, 2021, pp.103128. ⟨10.1016/j.isci.2021.103128⟩
Article dans une revue pasteur-03349141 v1
Image document

RadD Contributes to R-Loop Avoidance in Sub-MIC Tobramycin

Veronica Negro , Evelyne Krin , Sebastian Aguilar Pierlé , Thibault Chaze , Quentin Giai Gianetto et al.
mBio, 2019, 10 (4), pp.e01173-19. ⟨10.1128/mBio.01173-19⟩
Article dans une revue pasteur-02171194 v1
Image document

Influence of very short patch mismatch repair on SOS inducing lesions after aminoglycoside treatment in Escherichia coli.

Zeynep Baharoglu , Didier Mazel
Research in Microbiology, 2014, 165 (6), pp.476-80. ⟨10.1016/j.resmic.2014.05.039⟩
Article dans une revue pasteur-01423361 v1
Image document

Identification of genes involved in low aminoglycoside-induced SOS response in Vibrio cholerae: a role for transcription stalling and Mfd helicase.

Z. Baharoglu , A. Babosan , D. Mazel
Nucleic Acids Research, 2014, 42 (4), pp.2366-2379. ⟨10.1093/nar/gkt1259⟩
Article dans une revue pasteur-01423602 v1
Image document

SOS, the formidable strategy of bacteria against aggressions

Zeynep Baharoglu , Didier Mazel
FEMS Microbiology Reviews, 2014, 38 (6), pp.1126-1145. ⟨10.1111/1574-6976.12077⟩
Article dans une revue pasteur-01423593 v1
Image document

RpoS Plays a Central Role in the SOS Induction by Sub-Lethal Aminoglycoside Concentrations in Vibrio cholerae

Zeynep Baharoglu , Evelyne Krin , Didier Mazel
PLoS Genetics, 2013, 9 (4), pp.e1003421. ⟨10.1371/journal.pgen.1003421⟩
Article dans une revue pasteur-01691109 v1
Image document

β-lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity

A. Gutierrez , L. Laureti , S. Crussard , H. Abida , A. Rodríguez-Rojas et al.
Nature Communications, 2013, 4, pp.1610. ⟨10.1038/ncomms2607⟩
Article dans une revue pasteur-01691736 v1
Image document

Multiple Pathways of Genome Plasticity Leading to Development of Antibiotic Resistance

Zeynep Baharoglu , Geneviève Garriss , Didier Mazel
Antibiotics, 2013, Antibiotic Resistance, 2 (2), pp.288-315. ⟨10.3390/antibiotics2020288⟩
Article dans une revue pasteur-01691592 v1
Image document

Connecting Environment and Genome Plasticity in the Characterization of Transformation-Induced SOS Regulation and Carbon Catabolite Control of the Vibrio cholerae Integron Integrase

Zeynep Baharoglu , Evelyne Krin , Didier Mazel
Journal of Bacteriology, 2012, 194 (7), pp.1659-1667. ⟨10.1128/JB.05982-11⟩
Article dans une revue pasteur-03941970 v1
Image document

Vibrio cholerae triggers SOS and mutagenesis in response to a wide range of antibiotics: a route towards multiresistance.

Zeynep Baharoglu , Didier Mazel
Antimicrobial Agents and Chemotherapy, 2011, 55 (5), pp.2438-2441. ⟨10.1128/AAC.01549-10⟩
Article dans une revue pasteur-01423615 v1
Image document

RNA polymerase mutations that facilitate replication progression in the rep uvrD recF mutant lacking two accessory replicative helicases

Zeynep Baharoglu , Roxane Lestini , Stéphane Duigou , Bénédicte Michel
Molecular Microbiology, 2010, 77 (2), pp.324. ⟨10.1111/j.1365-2958.2010.07208.x⟩
Article dans une revue hal-00552639 v1
Image document

Conjugative DNA transfer induces the bacterial SOS response and promotes antibiotic resistance development through integron activation

Zeynep Baharoglu , David Bikard , Didier Mazel
PLoS Genetics, 2010, 6 (10), pp.e1001165. ⟨10.1371/journal.pgen.1001165⟩
Article dans une revue pasteur-02477623 v1
Image document

Folded DNA in Action: Hairpin Formation and Biological Functions in Prokaryotes

David Bikard , Céline Loot , Zeynep Baharoglu , Didier Mazel
Microbiology and Molecular Biology Reviews, 2010, 74 (4), pp.570-588. ⟨10.1128/MMBR.00026-10⟩
Article dans une revue pasteur-02505407 v1

Recombination proteins and rescue of arrested replication forks.

Bénédicte Michel , Hasna Boubakri , Zeynep Baharoglu , Marie Lemasson , Roxane Lestini
DNA Repair, 2007, 6 (7), pp.967-80. ⟨10.1016/j.dnarep.2007.02.016⟩
Article dans une revue istex hal-00167418 v1

RuvAB is essential for replication forks reversal in certain replication mutants.

Zeynep Baharoglu , Mirjana Petranovic , Maria-Jose Flores , Bénédicte Michel
EMBO Journal, 2006, 25 (3), pp.596-604. ⟨10.1038/sj.emboj.7600941⟩
Article dans une revue hal-00130946 v1