ZUZANA MACEK JILKOVA

Identifiants chercheurs

IdHAL :

zuzana-macek-jilkova

ORCID :

0000-0002-2553-5971

ResearcherID :

N-4051-2014

Publications

Article dans une revue (38)

Intratumoral PD-1high CD8+ T cells correlate with AFP levels in HCC patients: a brief report Zuzana Macek Jilkova,Julien Ghelfi,Lucile Dumolard,Christian Sengel,Bleuenn Brussetet al. Cellular Oncology, 2026, 49 (1), pp.39. ⟨10.1007/s13402-026-01170-0⟩ Article dans une revue hal-05509807v1
New Insights into Antibody-Mediated NK Cell Immunity in Hepatitis B: Editorial on &quot;Dissecting antibody-mediated NK cell effects reveals a cytotoxic CX3CR1⁺KLRC2⁻CD16hi subset linked to HBV outcomes Zuzana Macek Jilkova,Caroline Aspord Clinical and molecular hepatology, 2026, ⟨10.3350/cmh.2026.0025⟩ Article dans une revue hal-05509830v1
Metabolic dysregulation in regulatory T cells from patients with immune-mediated glomerular diseases Johan Noble,Zuzana Macek-Jilkova,Philippe Saas,Paolo Malvezzi,Miguel Fribourget al. Journal of Nephrology, 2025, ⟨10.1007/s40620-025-02306-5⟩ Article dans une revue hal-05105426v1
Identification of immunogenic HLA-A*02:01 epitopes associated with HCC for immunotherapy development Anthony Maino,Thomas Decaens,Saadi Khochbin,Zuzana Macek Jilkova,Sophie Rousseauxet al. Hepatology Communications, 2025, 9 (3), ⟨10.1097/HC9.0000000000000659⟩ Article dans une revue hal-05004966v1
HBV and HBsAg strongly reshape the phenotype, function, and metabolism of DCs according to patients’ clinical stage Lucile Dumolard,Theophile Gerster,Florent Chuffart,Thomas Decaens,Marie-Noelle Hilleretet al. Hepatology Communications, 2025, 9 (2), pp.276-284. ⟨10.1097/HC9.0000000000000625⟩ Article dans une revue hal-04940822v1
PD1 and TIM3 Expression is Associated with Very Early Hepatocellular Carcinoma Recurrence After Percutaneous Thermal Ablation Julien Ghelfi,Zuzana Macek Jilkova,Christian Sengel,Bleuenn Brusset,Yann Teyssieret al. Journal of Hepatocellular Carcinoma, 2024, 11, pp.39 - 50. ⟨10.2147/jhc.s443134⟩ Article dans une revue hal-05006680v1
Liver cancer in ovo models for preclinical testing Paul Garcia,Yan Wang,Jean Viallet,Nour El Houda Mehdi,Emilie Montautet al. FASEB Journal, 2024, 38 (17), pp.e70029. ⟨10.1096/fj.202401416R⟩ Article dans une revue hal-05003857v1
Hepatocellular carcinoma hosts cholinergic neural cells and tumoral hepatocytes harboring targetable muscarinic receptors Charlotte Hernandez,Claire Verzeroli,Armando Andres Roca Suarez,Abud Jose Farca Luna,Laurie Tononet al. JHEP Reports Innovation in Hepatology, 2024, 7 (1), pp.101245. ⟨10.1016/j.jhepr.2024.101245⟩ Article dans une revue hal-04876113v1
Role of Genetic and Epigenetic Modifications in the Progression of Hepatocellular Carcinoma in Chronic HCV Patients Anum Syyam,Hira Raheem Akbar,Zuzana Macek Jilkova,Samia Afzal Livers, 2023, 3 (1), pp.82-92. ⟨10.3390/livers3010008⟩ Article dans une revue (article de synthèse) hal-05007165v1
Intracellular accumulation and immunological response of NIR-II polymeric nanoparticles Iryna Moskalevska,Virginie Faure,Lucie Haye,Marion Mercey-Ressejac,Arindam Deyet al. International Journal of Pharmaceutics, 2023, 630, pp.122439. ⟨10.1016/j.ijpharm.2022.122439⟩ Article dans une revue hal-03972922v1
Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet Domenico Iuso,Isabel Garcia-Saez,Yohann Couté,Yoshiki Yamaryo-Botté,Elisabetta Boeri Erbaet al. Science Advances , 2023, 9 (36), pp.eadh0140. ⟨10.1126/sciadv.adh0140⟩ Article dans une revue hal-04216158v1
Effect of Novel AKT Inhibitor Vevorisertib as Single Agent and in Combination with Sorafenib on Hepatocellular Carcinoma in a Cirrhotic Rat Model Keerthi Kurma,Ayca Zeybek Kuyucu,Gaël Roth,Nathalie Sturm,Marion Mercey-Ressejacet al. International Journal of Molecular Sciences, 2022, 23 (24), pp.16206. ⟨10.3390/ijms232416206⟩ Article dans une revue hal-04651076v1
Enantioselective approach for expanding the three‐dimensional space of tetrahydroquinoline to develop bet bromodomain inhibitors Marie‐ange Lespinasse,Kaiyao Wei,Justine Perrin,Matthias Winkler,Sieme Hamaidiaet al. Chemistry - A European Journal, 2022, 28 (64), pp.e202202293. ⟨10.1002/chem.202202293⟩ Article dans une revue hal-03806738v1
Chronic Intermittent Hypoxia Increases Cell Proliferation in Hepatocellular Carcinoma Lydie Carreres,Marion Mercey-Ressejac,Keerthi Kurma,Julien Ghelfi,Carole Fournieret al. Cells, 2022, 11 (13), pp.2051. ⟨10.3390/cells11132051⟩ Article dans une revue hal-04649799v1
Gamma delta T cells in hepatocellular carcinoma: Sunrise of new therapy based on Vδ2 T cells? Zuzana Macek Jilkova Clinical and Translational Medicine, 2022, 12 (4), ⟨10.1002/ctm2.834⟩ Article dans une revue hal-05007097v1
Increased Intrahepatic Expression of Immune Checkpoint Molecules in Autoimmune Liver Disease Zuzana Macek Jilkova,Marie Noelle Hilleret,Theophile Gerster,Nathalie Sturm,Marion Mercey-Ressejacet al. Cells, 2021, 10 (10), pp.2671. ⟨10.3390/cells10102671⟩ Article dans une revue hal-05006859v1
NASH limits anti-tumour surveillance in immunotherapy-treated HCC Dominik Pfister,Nicolás Gonzalo Núñez,Roser Pinyol,Olivier Govaere,Matthias Pinteret al. Nature, 2021, 592 (7854), pp.450-456. ⟨10.1038/s41586-021-03362-0⟩ Article dans une revue hal-03258586v1
Modeling Diet-Induced NAFLD and NASH in Rats: A Comprehensive Review Lydie Carreres,Zuzana Macek Jílková,Guillaume Vial,Patrice N. Marche,Thomas Decaenset al. Biomedicines, 2021, 9 (4), pp.378. ⟨10.3390/biomedicines9040378⟩ Article dans une revue inserm-03655112v1
NASH limits anti-tumour surveillance in immunotherapy-treated HCC Dominik Pfister,Nicolás Gonzalo Núñez,Roser Pinyol,Olivier Govaere,Matthias Pinteret al. Nature, 2021, 592 (7854), pp.450-456. ⟨10.1038/s41586-021-03362-0⟩ Article dans une revue inserm-03348110v1
Targeting Akt in Hepatocellular Carcinoma and Its Tumor Microenvironment Mariam Mroweh,Gaël Roth,Thomas Decaens,Patrice Marche,Hervé Leratet al. International Journal of Molecular Sciences, 2021, 22 (4), pp.1794. ⟨10.3390/ijms22041794⟩ Article dans une revue inserm-03348116v1
GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions Sonia Brun,Eloïne Bestion,Eric Raymond,Firas Bassissi,Zuzana Macek Jilkovaet al. Autophagy, 2021, 18 (3), pp.678-694. ⟨10.1080/15548627.2021.1988357⟩ Article dans une revue (data paper) hal-04876759v1
GNS561, a New Autophagy Inhibitor Active against Cancer Stem Cells in Hepatocellular Carcinoma and Hepatic Metastasis from Colorectal Cancer Sonia Brun,Jean-Marc Pascussi,Elena Patricia Gifu,Eloïne Bestion,Zuzana Macek-Jilkovaet al. American Journal of Cancer, 2021, 12 (18), pp.5432-5438. ⟨10.7150/jca.58533⟩ Article dans une revue hal-03326462v1
Predictive Factors for Hepatocellular Carcinoma Development after Direct-Acting Antiviral Treatment of HCV Zuzana Macek Jilkova,Komal Saleem,Samia Afzal,Thomas Decaens Livers, 2021, 1 (4), pp.313-321. ⟨10.3390/livers1040024⟩ Article dans une revue hal-05006799v1
DEN-Induced Rat Model Reproduces Key Features of Human Hepatocellular Carcinoma Keerthi Kurma,Olivier Manches,Florent Chuffart,Nathalie Sturm,Khaldoun Gharzeddineet al. Cancers, 2021, 13 (19), pp.4981. ⟨10.3390/cancers13194981⟩ Article dans une revue hal-04649803v1
Percutaneous Ablation-Induced Immunomodulation in Hepatocellular Carcinoma Lucile Dumolard,Julien Ghelfi,Gael Roth,Thomas Decaens,Zuzana Macek Jilkova International Journal of Molecular Sciences, 2020, 21 (12), pp.4398. ⟨10.3390/ijms21124398⟩ Article dans une revue (article de synthèse) hal-05006882v1
Modulating the Crosstalk between the Tumor and Its Microenvironment Using RNA Interference: A Treatment Strategy for Hepatocellular Carcinoma Mariam Mroweh,Thomas Decaens,Patrice Marche,Zuzana Macek Jilkova,Flora Clément International Journal of Molecular Sciences, 2020, 21 (15), pp.5250. ⟨10.3390/ijms21155250⟩ Article dans une revue inserm-03348119v1
GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-β1 inhibition Eloïne Bestion,Zuzana Macek Jilkova,Jean-Louis Mège,Marie Novello,Keerthi Kurmaet al. Therapeutic Advances in Chronic Disease, 2020, 11, pp.204062232094204. ⟨10.1177/2040622320942042⟩ Article dans une revue hal-03677273v1
Circulating IL-13 Is Associated with De Novo Development of HCC in HCV-Infected Patients Responding to Direct-Acting Antivirals Zuzana Macek Jílková,Arnaud Seigneurin,Celine Coppard,Laurissa Ouaguia,Caroline Aspordet al. Cancers, 2020, 12 (12), pp.3820. ⟨10.3390/cancers12123820⟩ Article dans une revue hal-05007125v1
Reply to Comment on “Jilkova, Z.M.; et al. Predictive Factors for Response to PD-1/PD-L1 Checkpoint Inhibition in the Field of Hepatocellular Carcinoma: Current Status and Challenges” Cancers 2019, 11, 1554 Zuzana Macek Jilkova,Caroline Aspord,Thomas Decaens Cancers, 2020, 12 (9), pp.2673. ⟨10.3390/cancers12092673⟩ Article dans une revue inserm-05005566v1
Immunologic Features of Patients With Advanced Hepatocellular Carcinoma Before and During Sorafenib or Anti-programmed Death-1/Programmed Death-L1 Treatment Zuzana Macek Jilkova,Caroline Aspord,Keerthi Kurma,Anouck Granon,Christian Sengelet al. Clinical and translational gastroenterology, 2019, 10 (7), pp.e00058. ⟨10.14309/ctg.0000000000000058⟩ Article dans une revue inserm-02332361v1
Animal Models of Hepatocellular Carcinoma: The Role of Immune System and Tumor Microenvironment Zuzana Macek Jilkova,Keerthi Kurma,Thomas Decaens Cancers, 2019, 11 (10), pp.1487. ⟨10.3390/cancers11101487⟩ Article dans une revue (article de synthèse) hal-05006948v1
Predictive Factors for Response to PD-1/PD-L1 Checkpoint Inhibition in the Field of Hepatocellular Carcinoma: Current Status and Challenges Zuzana Macek Jilkova,Thomas Decaens,Caroline Aspord Cancers, 2019, 11 (10), pp.1554. ⟨10.3390/cancers11101554⟩ Article dans une revue (article de synthèse) hal-05006940v1
Combination of AKT inhibitor ARQ 092 and sorafenib potentiates inhibition of tumor progression in cirrhotic rat model of hepatocellular carcinoma Zuzana Macek Jilkova,Ayca Zeybek Kuyucu,Keerthi Kurma,Ahmad Pour,Gaël S Rothet al. Oncotarget, 2018, 9 (13), pp.11145-11158. ⟨10.18632/oncotarget.24298⟩ Article dans une revue inserm-02332894v1
Sex Differences in Spontaneous Degranulation Activity of Intrahepatic Natural Killer Cells during Chronic Hepatitis B: Association with Estradiol Levels Zuzana Macek Jilkova,Thomas Decaens,Alice Marlu,Hélène Marche,Evelyne Jouvin-Marcheet al. Mediators of Inflammation, 2017, 2017, pp.1-5. ⟨10.1155/2017/3214917⟩ Article dans une revue inserm-02333383v1
Progression of fibrosis in patients with chronic viral hepatitis is associated with IL-17 + neutrophils Zuzana Macek Jilkova,Samia Afzal,Hélène Marche,Thomas Decaens,Nathalie Sturmet al. Liver International, 2016, 36 (8), pp.1116-24. ⟨10.1111/liv.13060⟩ Article dans une revue inserm-02333978v1
CCM proteins control endothelial b1 integrin dependent response to shear stress Zuzana Macek Jilkova,Justyna Lisowska,Sandra Manet,Claude Verdier,Valerie Deplanoet al. Biology Open, 2014, 3 (12), pp.1228-1235. ⟨10.1242/bio.201410132⟩ Article dans une revue hal-01096964v1
Wall shear stress and endothelial cells dysfunction in the context of abdominal aortic aneurysms Zuzana Macek Jilkova,Valérie Deplano,Claude Verdier,Mamadou Toungara,Christian Geindreauet al. Computer Methods in Biomechanics and Biomedical Engineering, 2013, 16 (supp1), pp.27-29. ⟨10.1080/10255842.2013.815959⟩ Article dans une revue hal-00853100v1
The inhibition of fat cell proliferation by n-3 fatty acids in dietary obese mice Michal Hensler,Kristina Bardova,Zuzana Macek Jílková,Walter Wahli,Daniel Metzgeret al. Lipids in Health and Disease, 2011, 10 (1), pp.128. ⟨10.1186/1476-511X-10-128⟩ Article dans une revue hal-04977181v1

Poster de conférence (2)

Greener Pharmaceuticals: Short Organocatalyzed Synthesis of BD2 Selective Bromodomain Inhibitors Yung-Sing Wong,Marie‐ange Lespinasse,Kaiyao Wei,Julie Perrin,Matthias Winkleret al. RECOB 18, Mar 2022, Aussois, France Poster de conférence hal-04779015v1
GNS561, a new palmitoyl‐protein thioesterase 1 (PPT‐1) inhibitor, active against cancer stem cells in hepatocellular carcinoma and liver metastasis Sonia Brun,Jean-Marc Pascussi,Elena Patricia Gifu,Eloïne Bestion,Zuzana Macek Jílkováet al. American Association for the Study of Liver Diseases. AASLD 2021 - Liver Meeting 2021, Nov 2021, Virtuel - Online, United States. Wolters Kluwer Health, Inc, Hepatology, 74 (special), pp.817A, 1370, 2021 Poster de conférence hal-04770752v1

Communication dans un congrès (2)

Greener Pharmaceuticals: Short and Modular Enantioselective Organocatalyzed Synthesis of new BET Bromodomain Inhibitors with Anti-inflammatory Action Yung-Sing Wong,Marie‐ange Lespinasse,Kaiyao Wei,Julien Perrin,Matthias Winkleret al. 8th EuChemS Chemistry Congress, EuChemS, Aug 2022, Lisbon (Portugal), Portugal Communication dans un congrès hal-04776762v1
GNS561, A NEW LYSOSOMOTROPIC SMALL MOLECULE, FOR THE TREATMENT OF LIVER FIBROSIS Bestion, Eloine,Gilles Lalmanach,Marie Novello,Zuzana Macek Jilkova,Firas Bassissiet al. Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, Nov 2019, Boston, MA, United States. pp.1268A-1269A Communication dans un congrès hal-02466561v1

Brevet (1)

Tetrahydroquinoline (THQ) compounds Zuzana Macek Jílková,Jérôme Govin,Anouk Emadali,Carlo Petosa,Yung-Sing Wong France, Patent n° : WO2022248475 A1 20221201. 2021 Brevet hal-04864504v1