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Agata Nawrotek

10
Documents

Publications

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Molecular principles of bidirectional signalling between membranes and small GTPases

Agata Nawrotek , Pavlina Dubois , Mahel Zeghouf , Jacqueline Cherfils
FEBS Letters, 2023, Structure, function, and molecular mechanisms of small GTPases, 597 (6), pp.778 - 793. ⟨10.1002/1873-3468.14585⟩
Article dans une revue hal-04062256v1

Targeting non-alcoholic fatty liver disease: Design, X-ray co-crystal structure and synthesis of ‘first-in-kind’ inhibitors of serine/threonine kinase25

Scarlett Kiyeleko , Sofiane Hocine , Giséle Mautino , Mélaine Kuenemann , Agata Nawrotek
Bioorganic and Medicinal Chemistry Letters, 2022, 75, pp.128950. ⟨10.1016/j.bmcl.2022.128950⟩
Article dans une revue hal-03853246v1

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing

Sarah Adams , Andrew Purkiss , Phillip Knowles , Andrea Nans , David Briggs
Structure, 2021, 29 (7), pp.694-708.e7. ⟨10.1016/j.str.2020.12.012⟩
Article dans une revue hal-03853254v1
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Une moisson de nouvelles structures de mTORC1

Agata Nawrotek , Jacqueline Cherfils
Médecine/Sciences, 2021, 37 (4), pp.372-378. ⟨10.1051/medsci/2021033⟩
Article dans une revue hal-03211683v1

Protein–membrane interactions in small GTPase signalling and pharmacology: perspectives from Arf GTPases studies

Agata Nawrotek , Mahel Zeghouf , Jacqueline Cherfils
Biochemical Society Transactions, 2020, 48 (6), pp.2721-2728. ⟨10.1042/BST20200482⟩
Article dans une revue hal-03330403v1

PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling

Agata G Nawrotek , Sarah Benabdi , Supaporn Niyomchon , Marie-Hélène Kryszke , Christophe Ginestier
Nature Chemical Biology, 2019, 15 (4), pp.358-366. ⟨10.1038/s41589-019-0228-3⟩
Article dans une revue hal-02371687v1

Publisher Correction: PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling

Agata G Nawrotek , Sarah Benabdi , Supaporn Niyomchon , Marie-Hélène Kryszke , Christophe Ginestier
Nature Chemical Biology, 2019, 15 (5), pp.549-549. ⟨10.1038/s41589-019-0255-0⟩
Article dans une revue hal-02145628v1
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Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes

Sanchaita Das , Andrew W Malaby , Agata G Nawrotek , Wenhua Zhang , Mahel Zeghouf
Structure, 2019, 27, pp.1 - 16. ⟨10.1016/j.str.2019.09.007⟩
Article dans une revue hal-02363241v1
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Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniae

Agata G Nawrotek , Beatriz G Guimarães , Christophe G Velours , Agathe Subtil , Marcel G Knossow
Journal of Biological Chemistry, 2014, 289 (36), pp.25199-25210. ⟨10.1074/jbc.M114.568436⟩
Article dans une revue pasteur-01448078v1

The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin

Agata Nawrotek , Marcel Knossow , Benoît Gigant
Journal of Molecular Biology, 2011, 412 (1), pp.35-42. ⟨10.1016/j.jmb.2011.07.029⟩
Article dans une revue hal-02120600v1