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Research Scientist in Green Chemistry


Ph.D holder since november 2020, after 8 years as chemical engineer, my research is dedicated to implement green chemistry on various bio-sourced compounds to bring innovation in fields such as biocontrol, cosmetics, polymers. My expertise is mainly on phenolic compounds with a notable exception for the derivatives of levoglucosenone. However, curious and dynamic by nature, I am highly interested in all projects related to green chemistry.


Journal articles27 documents

  • Temitope T. Abiola, Josene M. Toldo, Mariana Telles Do Casal, Amandine L. Flourat, Benjamin Rioux, et al.. Direct structural observation of ultrafast photoisomerization dynamics in sinapate esters. Communications Chemistry, Nature Research 2022, 5 (141), pp.1-9. ⟨10.1038/s42004-022-00757-6⟩. ⟨hal-03839302⟩
  • Julien Vinet, Amandine L Flourat, Cédric Peyrot, Fanny Brunois, Fanny Brunissen, et al.. Optimization and Green Metrics Analysis of the AgOAc-Mediated Dimerization of Piceid: Toward a High-Yielding and More Sustainable Access to δ-Viniferin and Synthesis of New Piceid Dimers. ACS Sustainable Chemistry & Engineering, American Chemical Society, 2022, 10 (28), pp.9166-9175. ⟨10.1021/acssuschemeng.2c02010⟩. ⟨hal-03722982⟩
  • Amandine Flourat, Nour Zeaiter, Erwan Vallée, V. Nguyen, Sami Fadlallah, et al.. A sustainable preparative-scale chemo-enzymatic synthesis of 6-hydroxy-5,7-dimethoxy-2-naphthoic acid (DMNA) from sinapic acid. Green chemistry letters and reviews, 2022, 15 (3), pp.557-571. ⟨10.1080/17518253.2022.2115317⟩. ⟨hal-03843396⟩
  • Sami Fadlallah, Amandine Flourat, Louis Mouterde, Mattia Annatelli, Aurélien Peru, et al.. Sustainable Hyperbranched Functional Materials via Green Polymerization of Readily Accessible Levoglucosenone‐Derived Monomers. Macromolecular Rapid Communications, Wiley-VCH Verlag, 2021, 42 (19), pp.2100284. ⟨10.1002/marc.202100284⟩. ⟨hal-03473099⟩
  • Amandine Flourat, Jeanne Combes, Claire Bailly-Maitre-Grand, Kevin Magnien, Arnaud Haudrechy, et al.. Accessing p‐Hydroxycinnamic acids: chemical synthesis, biomass recovery or engineered microbial production?. ChemSusChem, ChemPubSoc Europe/Wiley, 2021, 14 (1), pp.118-129. ⟨10.1002/cssc.202002141⟩. ⟨hal-02980663⟩
  • Ezinne C. Achinivu, Amandine Flourat, Fanny Brunissen, Florent Allais. Valorization of waste biomass from oleaginous “oil-bearing” seeds through the biocatalytic production of sinapic acid from mustard bran. Biomass and Bioenergy, Elsevier, 2021, 145, pp.105940. ⟨10.1016/j.biombioe.2020.105940⟩. ⟨hal-03492936⟩
  • Morad Chadni, Amandine Flourat, Valentin Reungoat, Louis M M Mouterde, Florent Allais, et al.. Selective Extraction of Sinapic Acid Derivatives from Mustard Seed Meal by Acting on pH: Toward a High Antioxidant Activity Rich Extract. Molecules, MDPI, 2021, 26, pp.212. ⟨10.3390/molecules26010212⟩. ⟨hal-03104017⟩
  • Lewis A Baker, Michael Staniforth, Amandine Flourat, Florent Allais, Vasilios G Stavros. Conservation of ultrafast photoprotective mechanisms with increasing molecular complexity in sinapoyl malate derivatives. ChemPhysChem, Wiley-VCH Verlag, 2020, 21 (17), pp.2006-2011. ⟨10.1002/cphc.202000429⟩. ⟨hal-03473143⟩
  • Amandine Flourat, Arnaud Haudrechy, Florent Allais, Jean-Hugues Renault. (S)-γ-hydroxymethyl-α,β-butenolide (aka HBO), a Valuable Chiral Synthon: Syntheses, Reactivity and Applications. Organic Process Research and Development, American Chemical Society, 2020, 24 (5), pp.615-636. ⟨10.1021/acs.oprd.9b00468⟩. ⟨hal-02400639⟩
  • Mathilde Leriche-Grandchamp, Amandine Flourat, Hangchen Shen, Flavien Picard, Heloïse Giordana, et al.. Inhibition of Phenolics Uptake by Ligninolytic Fungal Cells and Its Potential as a Tool for the Production of Lignin-Derived Aromatic Building Blocks. Journal of Fungi, MDPI, 2020, 6 (4), pp.362. ⟨10.3390/jof6040362⟩. ⟨hal-03064264⟩
  • Valentin Reungoat, Morvan Gaudin, Amandine Flourat, Emilie Isidore, Louis M.M. Mouterde, et al.. Optimization of an ethanol/water-based sinapine extraction from mustard bran using Response Surface Methodology. Food and Bioproducts Processing, Elsevier, 2020, 122, pp.322-331. ⟨10.1016/j.fbp.2020.06.001⟩. ⟨hal-02893579⟩
  • Michael D Horbury, Matthew a P Turner, Jack S Peters, Matthieu Mention, Amandine Flourat, et al.. Exploring the Photochemistry of an Ethyl Sinapate Dimer: An Attempt Toward a Better Ultraviolet Filter. Frontiers in Chemistry, Frontiers Media, 2020, 8, pp.633. ⟨10.3389/fchem.2020.00633⟩. ⟨hal-03473130⟩
  • Sami Fadlallah, Aurélien A.M. Peru, Amandine Flourat, Florent Allais. A straightforward access to functionalizable polymers through ring-opening metathesis polymerization of levoglucosenone-derived monomers. European Polymer Journal, Elsevier, 2020, 138, pp.109980. ⟨10.1016/j.eurpolymj.2020.109980⟩. ⟨hal-03473137⟩
  • Amandine Flourat, Aurélien a M Peru, Arnaud Haudrechy, Jean-Hugues Renault, Florent Allais. First Total Synthesis of (β-5)-(β-O-4) Dihydroxytrimer and Dihydrotrimer of Coniferyl Alcohol (G): Advanced Lignin Model Compounds. Frontiers in Chemistry, Frontiers Media, 2019, 7, pp.842. ⟨10.3389/fchem.2019.00842⟩. ⟨hal-02400612⟩
  • Leïla Bonnaud, Benjamin Chollet, Ludovic Dumas, Aurélien A. M. Peru, Amandine Flourat, et al.. High-Performance Bio-Based Benzoxazines from Enzymatic Synthesis of Diphenols. Macromolecular Chemistry and Physics, Wiley-VCH Verlag, 2019, 220, pp.1800312. ⟨10.1002/macp.201800312⟩. ⟨hal-02012178⟩
  • Amandine Flourat, Gaëlle Willig, Andreia Teixeira, Florent Allais. Eco-Friendly Extraction of Sinapine From Residues of Mustard Production. Frontiers in Sustainable Food Systems, Frontiers Media, 2019, 3, ⟨10.3389/fsufs.2019.00012⟩. ⟨hal-02400663⟩
  • Guillaume Bonneau, Aurélien A. M. Peru, Amandine Flourat, Florent Allais. Organic solvent- and catalyst-free Baeyer–Villiger oxidation of levoglucosenone and dihydrolevoglucosenone (Cyrene®): a sustainable route to ( S )-γ-hydroxymethyl-α,β-butenolide and ( S )-γ-hydroxymethyl-γ-butyrolactone. Green Chemistry, Royal Society of Chemistry, 2018, 20 (11), pp.2455-2458. ⟨10.1039/c8gc00553b⟩. ⟨hal-03473084⟩
  • Andreia R. S. Teixeira, Gaëlle Willig, Julien Couvreur, Amandine Flourat, Aurélien A. M. Peru, et al.. From bench scale to kilolab production of renewable ferulic acid-based bisphenols: optimisation and evaluation of different purification approaches towards technical feasibility and process environmental sustainability. Reaction Chemistry & Engineering, Royal Society of Chemistry, 2017, 2 (3), pp.406-419. ⟨10.1039/c7re00017k⟩. ⟨hal-02624985⟩
  • Jian Luo, Yan Liu, Songqiu Yang, Amandine Flourat, Florent Allais, et al.. Ultrafast barrierless photoisomerization and strong ultraviolet absorption of photoproducts in plant sunscreens. Journal of Physical Chemistry Letters, American Chemical Society, 2017, 8 (5), pp.1025-1030. ⟨10.1021/acs.jpclett.7b00083⟩. ⟨hal-01604320⟩
  • Andreia Teixeira, Amandine Flourat, Aurelien A. M. Peru, Fanny Brunissen, Florent Allais. Lipase-Catalyzed Baeyer-Villiger Oxidation of Cellulose-Derived Levoglucosenone into (S)-γ-Hydroxymethyl-α,β-Butenolide: Optimization by Response Surface Methodology. Frontiers in Chemistry, Frontiers Media, 2016, 4, pp.16. ⟨10.3389/fchem.2016.00016⟩. ⟨hal-01598622⟩
  • Aurélien Peru, Amandine Flourat, Christian Gunawan, Warwick Raverty, Martyn Jevric, et al.. Chemo-Enzymatic Synthesis of Chiral Epoxides Ethyl and Methyl (S)-3-(Oxiran-2-yl)propanoates from Renewable Levoglucosenone: An Access to Enantiopure (S)-Dairy Lactone. Molecules, MDPI, 2016, 21 (8), pp.988. ⟨10.3390/molecules21080988⟩. ⟨hal-01598617⟩
  • Imane Barbara, Amandine Flourat, Florent Allais. Renewable polymers derived from ferulic acid and biobased diols via ADMET. European Polymer Journal, Elsevier, 2015, 62, pp.236-243. ⟨10.1016/j.eurpolymj.2014.11.035⟩. ⟨hal-01598634⟩
  • Grégoire Burgé, Amandine Flourat, Brigitte B. Pollet, Henry-Eric Spinnler, Florent Allais. Erratum to "3-Hydroxypropionaldehyde (3-HPA) quantification by HPLC using a synthetic acrolein-free 3-hydroxypropionaldehyde system as analytical standard" [RSC Adv., 5 (2015) p. 92619]. RSC Advances, Royal Society of Chemistry, 2015, 5 (117), pp.96870. ⟨10.1039/c5ra90099a⟩. ⟨hal-02631894⟩
  • Grégoire Burgé, Claire Saulou-Berion, Marwen Moussa, Brigitte Pollet, Amandine Flourat, et al.. Diversity of Lactobacillus reuteri Strains in Converting Glycerol into 3-Hydroxypropionic Acid. Applied Biochemistry and Biotechnology, Humana Press, 2015, 177 (4), pp.923 - 939. ⟨10.1007/s12010-015-1787-8⟩. ⟨hal-01562839⟩
  • Amandine Flourat, Aurélien Peru, Andreia Teixeira, Fanny Brunissen, Florent Allais. Chemo-enzymatic synthesis of key intermediates (S)-gamma-hydroxymethyl-alpha,beta- butenolide and (S)-gamma-hydroxymethyl-gamma-butyrolactone via lipase-mediated Baeyer-Villiger oxidation of levoglucosenone. Green Chemistry, Royal Society of Chemistry, 2015, 17 (1), pp.404 - 412. ⟨10.1039/c4gc01231c⟩. ⟨hal-01195511⟩
  • Grégoire Burgé, Amandine Flourat, Brigitte Pollet, Henry-Eric Spinnler, Florent Allais. 3-Hydroxypropionaldehyde (3-HPA) quantification by HPLC using a synthetic acrolein-free 3-hydroxypropionaldehyde system as analytical standard. RSC Advances, Royal Society of Chemistry, 2015, 5 (112), pp.92619 - 92627. ⟨10.1039/c5ra18274c⟩. ⟨hal-01535299⟩
  • Louis Mouterde, Amandine Flourat, Molly Cannet, Paul Henri Ducrot, Florent Allais. Chemoenzymatic Total Synthesis of a Naturally Occurring (5-5 ')/(8 '-O-4 '') Dehydrotrimer of Ferulic Acid. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2013, pp.173 - 179. ⟨10.1002/ejoc.201201290⟩. ⟨hal-01019100⟩

Conference papers5 documents

  • Amandine Flourat, Vinh-Phuc-Thinh Nguyen, Nour Zaiter, Erwan Vallee, Sami Fadlallah, et al.. Three steps-one pot conversion of sinapic acid into DMNA (6-hydroxy-5,7-dimethoxyl naphtoic acid). International Symposium of Green Chemistry 2022 (ISGC2022), May 2022, La Rochelle, France. ⟨hal-03821629⟩
  • Enzo Petracco, Amandine Flourat, Marie-Charlotte Belhomme, Stéphanie Castex, Fanny Brunissen, et al.. Eco-friendly synthesis of (R)-3-hydroxydecanoic acid and analogues: New green pathway to highly potent elicitor(s) of plant immune system. 3ème Symposium international Plant BioProtect, Jun 2022, Reims, France. ⟨hal-03821638⟩
  • Amandine Flourat, Enzo Petracco, Stéphanie Castex, Marie-Charlotte Belhomme, Florent Allais, et al.. Synthèse verte de chaînes grasses de rhamnolipides. Journées Jeunes Chercheurs Condorcet 2021, Jan 2021, Online, France. ⟨hal-03821644⟩
  • Amandine Flourat, Enzo Petracco, Marie-Charlotte Belhomme, Stéphanie Castex, Florent Allais, et al.. Eco-friendly synthesis of (R)-3hydroxydecanoic acid and analogues: New green pathway to highly potent elicitor(s) of plant immune system. 6th Green & Sustainable Chemistry Conference, Nov 2021, Online, France. ⟨hal-03821650⟩
  • Amandine Flourat. Laccase Trametes versicolor: a versatile enzyme for the selective biocatalyzed C-C coupling of phenolic compounds. 28ème colloque du Club Biocatalyse en Synthèse Organique (CBSO), Sep 2021, Lège Cap-Ferret, France. ⟨hal-03821645⟩

Book sections1 document

  • Florian Pion, Armando, Félix Reano, Zahahe Mouandhoime, Isabelle Barbara, Amandine Flourat, et al.. Chemo-enzymatic Synthesis, Derivatizations, and Polymerizations of Renewable Phenolic Monomers Derived from Ferulic Acid and Biobased Polyols : An access to Sustainable Copolyesters, Poly(esther-urethane)s, and Poly(ester-alkenamer)s. Green Polymer Chemistry: Biobased Materials and Biocatalysis, 1192, ACS - American Chemical Society, 2015, ACS Symposium Series, 9780841230651. ⟨10.1021/bk-2015-1192.ch004⟩. ⟨hal-01195518⟩

Patents3 documents

  • Florent Allais, Guillaume Bonneau, Aurélien Peru, Amandine Flourat. METHOD FOR CONVERTING LEVOGLUCOSENONE INTO 4-HYDROXYMETHYL BUTYROLACTONE AND 4-HYDROXYMETHYL BUTENOLIDE WITHOUT USING ANY ORGANIC SOLVENT AND CATALYST. France, Patent n° : FR20160056565 20160707 / WO2017FR51848 20170706. 2016. ⟨hal-01787810⟩
  • Florent Allais, Amandine Flourat, Aurélien Peru, Ben Greatrex, Douglas Warwick, et al.. METHOD FOR SYNTHESIZING A PRECURSOR OF A SINGLE DAIRY-LACTONE ISOMER . France, Patent n° : FR20150053112 20150410 / WO2016FR50813 20160408. 2015. ⟨hal-01787794⟩
  • Florent Allais, Amandine Flourat, Aurélien Peru, Andreia Teixeira, Fanny Brunissen, et al.. METHOD FOR TRANSFORMING LEVOGLUCOSENONE INTO 4-HYDROXYMETHYN BUTYROLACTONE OR 4-HYDROXYMETHYL BUTENOLIDE . France, Patent n° : FR20140053957 20140430 / WO2015EP59323 20150429. 2014. ⟨hal-01787823⟩