Andrea Hemmerlin

22
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Publications

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Protein Prenylation Makeovers in Plants: Insights into Substrate Diversification

Quentin Chevalier , Pauline Debié , Alexandre Huchelmann , Andréa Hemmerlin
International Journal of Molecular Sciences, 2025, 26 (21), pp.10638. ⟨10.3390/ijms262110638⟩
Article dans une revue hal-05368558 v1
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Methyl-Jasmonate Functions as a Molecular Switch Promoting Cross-Talk between Pathways for the Biosynthesis of Isoprenoid Backbones Used to Modify Proteins in Plants

Quentin Chevalier , Alexandre Huchelmann , Pauline Debié , Pierre Mercier , Michael Hartmann et al.
Plants, 2024, 13 (8), pp.1110. ⟨10.3390/plants13081110⟩
Article dans une revue hal-04551982 v1
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Synthesis and Photochemical Properties of Fluorescent Metabolites Generated from Fluorinated Benzoylmenadiones in Living Cells

Nathan Trometer , Bogdan Cichocki , Quentin Chevalier , Jérémy Pécourneau , Jean-Marc Strub et al.
Journal of Organic Chemistry, 2023, ⟨10.1021/acs.joc.3c00620⟩
Article dans une revue hal-04157610 v1
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Phosphorylation of Metabolites Involved in Salvage Pathways for Isoprenoid Biosynthesis in Plants

Andréa Hemmerlin
Kinases and Phosphatases, 2023, 1 (3), pp.151-166. ⟨10.3390/kinasesphosphatases1030010⟩
Article dans une revue (article de synthèse) hal-04157584 v1
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Unravelling the Puzzle of Anthranoid Metabolism in Living Plant Cells Using Spectral Imaging Coupled to Mass Spectrometry

Quentin Chevalier , Jean-Baptiste Galle , Nicolas Wasser , Valérie Mazan , Claire Villette et al.
Metabolites, 2021, 11 (9), pp.571. ⟨10.3390/metabo11090571⟩
Article dans une revue hal-03329421 v1

A plastid‐localized geranylgeranyl diphosphate synthase plays a necessary role in monoterpene indole alkaloid biosynthesis in Catharanthus roseus

Sarma Rajeev Kumar , Avanish Rai , Dikki Pedenla Bomzan , Krishna Kumar , Andrea Hemmerlin et al.
The Plant Journal, 2020, ⟨10.1111/tpj.14725⟩
Article dans une revue hal-02885725 v1

The specific molecular architecture of plant 3-hydroxy-3-methylglutaryl-CoA lyase

Andrea Hemmerlin , Alexandre Huchelmann , Denis Tritsch , Hubert Schaller , Thomas Bach
Journal of Biological Chemistry, 2019, pp.jbc.RA119.008839. ⟨10.1074/jbc.RA119.008839⟩
Article dans une revue hal-02354866 v1

Synthesis and biological evaluation of phosphate isoters of fosmidomycin and analogs as inhibitors of Escherichia coli and Mycobacterium smegmatis 1-deoxyxylulose 5-phosphate reductoisomerases

Mathilde Munier , Denis Tritsch , Fanny Krebs , Jérémy Esque , Andrea Hemmerlin et al.
Bioorganic and Medicinal Chemistry, 2017, 25 (2), pp.684-689
Article dans une revue hal-01524438 v1

Synthesis and biological evaluation of phosphate isosters of fosmidomycin and analogs as inhibitors of Escherichia coli and Mycobacterium smegmatis 1-deoxyxylulose 5-phosphate reductoisomerases

Mathilde Munier , Denis Tritsch , Fanny Krebs , Jeremy Esque , Andrea Hemmerlin et al.
Bioorganic and Medicinal Chemistry Letters, 2017, 25 (2), pp.684-689. ⟨10.1016/j.bmc.2016.11.040⟩
Article dans une revue hal-02388655 v1

The potential of the mevalonate pathway for enhanced isoprenoid production

Pan Liao , Andrea Hemmerlin , Thomas J. Bach , Mee-Len Chye
Biotechnology Advances, 2016, 34 (5), pp.697-713. ⟨10.1016/j.biotechadv.2016.03.005⟩
Article dans une revue hal-02429879 v1

Farnesol-mediated shift in the metabolic origin of prenyl groups used for protein prenylation in plants

Alexandre Huchelmann , Mathieu Semir Brahim , Esther Gerber , Denis Tritsch , Thomas Bach et al.
Biochimie, 2016, 127, pp.95-102. ⟨10.1016/j.biochi.2016.04.021⟩
Article dans une revue hal-02446553 v1

Profiling of defense responses in Escherichia coli treated with fosmidomycin

A. Hemmerlin , D. Tritsch , P. Hammann , M. Rohmer , T.J. Bach
Biochimie, 2014, 99, pp.54-62
Article dans une revue hal-00951637 v1

Past achievements, current status and future perspectives of studies on 3-hydroxy-3-methylglutaryl-CoA synthase (HMGS) in the mevalonate (MVA) pathway

P. Liao , H. Wang , A. Hemmerlin , D.A. Nagegowda , T.J. Bach et al.
Plant Cell Reports, 2014, 33, pp.1005-1022
Article dans une revue hal-01010000 v1

S-Carvone suppresses cellulase-induced capsidiol production in Nicotiana tabacum by interfering with protein isoprenylation

A. Huchelmann , C. Gastaldo , M. Veinante , Y. Zeng , D. Heintz et al.
Plant Physiology, 2014, 164 (2), pp.935-950. ⟨10.1104/pp.113.232546⟩
Article dans une revue hal-00944148 v1

The effect of MEP pathway and other inhibitors on the intracellular localization of a plasma membrane-targeted, isoprenylable GFP reporter protein in tobacco BY-2 cells

M. Hartmann , A. Hemmerlin , E. Gas-Pascual , E. Gerber , D. Tritsch et al.
F1000Research, 2013, 2, pp.170. ⟨10.12688/f1000research.2-170.v2⟩
Article dans une revue hal-00906319 v1

Post-translational events and modifications regulating plant enzymes involved in isoprenoid precursor biosynthesis

A. Hemmerlin
Plant Science, 2013, 203-204, pp.41-54
Article dans une revue hal-00819862 v1

A raison d'être for two distinct pathways in the early steps of plant isoprenoid biosynthesis ?

A. Hemmerlin , J.L. Harwood , T. Bach
Progress in Lipid Research, 2012, 51 (2), pp.95-148
Article dans une revue hal-00680351 v1

Plant isoprenoid biosynthesis via the MEP pahtway: in vivo IPP/DMAPP ratio produced by (/E/) -4- hydroxy-3-methylbut-2-enyl diphosphate reductase in tobacco BY-2 cell cultures.

D. Tritsch , A. Hemmerlin , T.J. Bach , M. Rohmer
FEBS Letters, 2010, 584, pp.129-134
Article dans une revue hal-00453438 v1

The Plastidial 2-C-Methyl-D-Erythritol 4-Phosphate Pathway Provides the Isoprenyl Moiety for Protein Geranylgeranylation in Tobacco BY-2 Cells

E. Gerber , A. Hemmerlin , M. Hartmann , D. Heintz , M. A. Hartmann et al.
The Plant cell, 2009, 21, pp.285-300
Article dans une revue hal-00367312 v1

A serine involved in actin-dependent subcellular localization of a stress-induced tobacco BY-2 hydroxymethylglutaryl-CoA reductase isoform

R. Merret , J. Cirioni , T. Bach , A. Hemmerlin
FEBS Letters, 2007, 581, pp.5295-5299
Article dans une revue hal-00187908 v1

Monitoring farnesol-induced toxicity in tobacco BY-2 cells with a fluorescent analog

A. Hemmerlin , R. Reents , J. Mutterer , Jf Feldtrauer , H. Waldmann et al.
Archives of biochemistry and biophysics., 2006, 448, pp.93-103
Article dans une revue hal-00092890 v1

A cytosolic Arabidopsis D-xylulose kinase catalyzes the phosphorylation of 1-deoxy-D-xylulose into a precursor of the plastidial isoprenoid pathway

A. Hemmerlin , D. Tritsch , M. Hartmann , K. Pacaud , J.F. Hoeffler et al.
Plant Physiology, 2006, 142, pp.441-457
Article dans une revue hal-00112341 v1