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Antoine TALY



Optical control of PIEZO1 channels

Francisco Andrés Peralta , Mélaine Balcon , Adeline Martz , Deniza Biljali , Federico Cevoli et al.
Nature Communications, 2023, 14 (1), pp.1269. ⟨10.1038/s41467-023-36931-0⟩
Journal articles hal-04030606v1
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Mutational analysis to explore long-range allosteric couplings involved in a pentameric channel receptor pre-activation and activation

Solène N. Lefebvre , Antoine Taly , Anaïs Menny , Karima Medjebeur , Pierre-Jean Corringer et al.
eLife, 2021, 10, pp.e60682. ⟨10.7554/eLife.60682⟩
Journal articles hal-03369647v2

GABAA Receptor Subunit Composition Drives Its Sensitivity to the Insecticide Fipronil

Zineb Soualah , Antoine Taly , Lucille Crespin , Ophélie Saulais , Daniel Henrion et al.
Frontiers in Neuroscience, 2021, 15, ⟨10.3389/fnins.2021.768466⟩
Journal articles hal-03821899v1

Modèle exploratoire de la dissonance et de l'harmonie ludo-narrative dans les jeux d’évasion

Antoine Taly , Annelyse Nugue , Michael Freudenthal
Sciences du jeu, 2021, 16, ⟨10.4000/sdj.3718⟩
Journal articles halshs-03698590v1
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Partial Agonist Activity of Neonicotinoids on Rat Nicotinic Receptors: Consequences over Epinephrine Secretion and In Vivo Blood Pressure

Joohee Park , Antoine Taly , Jennifer Bourreau , Frédéric de Nardi , Claire Legendre et al.
International Journal of Molecular Sciences, 2021, 22 (10), pp.5106. ⟨10.3390/ijms22105106⟩
Journal articles hal-03240635v1
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Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology

Damien Lemoine , Sarah Mondoloni , Jérome Tange , Bertrand Lambolez , Philippe Faure et al.
eLife, 2020, 9, pp.e59026. ⟨10.7554/eLife.59026⟩
Journal articles hal-03087878v1
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XPO1E571K Mutation Modifies Exportin 1 Localisation and Interactome in B-cell Lymphoma

Hadjer Miloudi , Elodie Bohers , François Guillonneau , Antoine Taly , Vincent Cabaud Gibouin et al.
Cancers, 2020, 12 (10), pp.2829. ⟨10.3390/cancers12102829⟩
Journal articles hal-02957363v1
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A Molecular Perspective on Mitochondrial Membrane Fusion: From the Key Players to Oligomerization and Tethering of Mitofusin

Dario de Vecchis , Astrid Brandner , Marc Baaden , Mickaël M Cohen , Antoine Taly et al.
Journal of Membrane Biology, 2019, 252 (4-5), pp.293-306. ⟨10.1007/s00232-019-00089-y⟩
Journal articles hal-02345040v1
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Structural dataset from microsecond-long simulations of yeast mitofusin Fzo1 in the context of membrane docking

Astrid Brandner , Dario de Vecchis , Marc Baaden , Mickaël M Cohen , Antoine Taly et al.
Data in Brief, 2019, 26, pp.104460. ⟨10.1016/j.dib.2019.104460⟩
Journal articles hal-02345034v1
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Physics-based oligomeric models of the yeast mitofusin Fzo1 at the molecular scale in the context of membrane docking

Astrid Brandner , Dario de Vecchis , Marc Baaden , Mickaël M Cohen , Antoine Taly et al.
Mitochondrion, 2019, 49, pp.234-244. ⟨10.1016/j.mito.2019.06.010⟩
Journal articles hal-02345043v1
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Involvement of the GABAA receptor α subunit in the mode of action of etifoxine

César Mattei , Antoine Taly , Zineb Soualah , Ophélie Saulais , Daniel Henrion et al.
Pharmacological Research, 2019, 145, pp.104250. ⟨10.1016/j.phrs.2019.04.034⟩
Journal articles hal-02344585v1
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Molecular modelling as the spark for active learning approaches for interdisciplinary biology teaching

Antoine Taly , F. Nitti , Marc Baaden , S. Pasquali
Interface Focus, 2019, 9 (3), pp.20180065. ⟨10.1098/rsfs.2018.0065⟩
Journal articles hal-02345057v1
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An inter‐dimer allosteric switch controls NMDA receptor activity

Jean‐baptiste Esmenjaud , David Stroebel , Kelvin Chan , Teddy Grand , Mélissa David et al.
EMBO Journal, 2018, 38 (2), pp.e99894. ⟨10.15252/embj.201899894⟩
Journal articles inserm-02438969v1
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Ten simple rules to create a serious game, illustrated with examples from structural biology

Marc Baaden , Olivier Delalande , Nicolas Ferey , Samuela Pasquali , Jérôme Waldispühl et al.
PLoS Computational Biology, 2018, 14 (3), pp.e1005955. ⟨10.1371/journal.pcbi.1005955⟩
Journal articles hal-01744190v1
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XPO1 in B cell hematological malignancies: from recurrent somatic mutations to targeted therapy

Vincent Camus , Hadjer Miloudi , Antoine Taly , Brigitte Sola , Fabrice Jardin et al.
Journal of Hematology and Oncology, 2017, 10 (1), pp.515-519. ⟨10.1186/s13045-017-0412-4⟩
Journal articles hal-02329725v1
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What Can Human-Guided Simulations Bring to RNA Folding?

Liuba Mazzanti , Sébastien Doutreligne , Cédric Gageat , Philippe Derreumaux , Antoine Taly et al.
Biophysical Journal, 2017, 113 (2), pp.302 - 312. ⟨10.1016/j.bpj.2017.05.047⟩
Journal articles hal-01644519v1
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A membrane-inserted structural model of the yeast mitofusin Fzo1

Dario de Vecchis , Laetitia Cavellini , Marc Baaden , Jérôme Hénin , Mickaël M. Cohen et al.
Scientific Reports, 2017, 7 (1), pp.10217. ⟨10.1038/s41598-017-10687-2⟩
Journal articles hal-01581980v1

Evolution of Pentameric Ligand-Gated Ion Channels: Pro-Loop Receptors.

Mariama Jaiteh , Antoine Taly , Jérôme Hénin
PLoS ONE, 2016, 11, pp.e0151934. ⟨10.1371/journal.pone.0151934⟩
Journal articles hal-01497980v1

Stay Wet, Stay Stable? How Internal Water Helps the Stability of Thermophilic Proteins

Debashree Chakraborty , Antoine Taly , Fabio Sterpone
Journal of Physical Chemistry B, 2015, 119 (40), pp.12760--12770
Journal articles hal-01498017v1

The plastid terminal oxidase: its elusive function points to multiple contributions to plastid physiology

W. J. Nawrocki , N. J. Tourasse , Antoine Taly , F. Rappaport , F. A. Wollman et al.
Annual Review of Plant Biology, 2015, 66 (1), pp.49--74
Journal articles hal-01498013v1
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Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure.

Gustavo Moraga-Cid , Ludovic Sauguet , Christèle Huon , Laurie Malherbe , Christine Girard-Blanc et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (9), pp.2865-70. ⟨10.1073/pnas.1417864112⟩
Journal articles hal-01230762v1

Allosteric regulation of pentameric ligand-gated ion channels: An emerging mechanistic perspective

Antoine Taly , Jérôme Hénin , Jean-Pierre Changeux , Marco Cecchini
Channels, 2014, 8 (4), pp.350-360. ⟨10.4161/chan.29444⟩
Journal articles hal-01498037v1
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Long distance effect on ligand-gated ion channels extracellular domain may affect interactions with the intracellular machinery

Maurice Garret , Eric Boué-Grabot , Antoine Taly
Communicative and Integrative Biology, 2014, pp.e27984-1. ⟨10.4161/cib.27984⟩
Journal articles hal-01146647v1
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A Mutation Causes MuSK Reduced Sensitivity to Agrin and Congenital Myasthenia

Asma Ben Ammar , Payam Soltanzadeh , Stéphanie Bauché , Pascale Richard , Evelyne Goillot et al.
PLoS ONE, 2013, 8 (1), pp.e53826. ⟨10.1371/journal.pone.0053826⟩
Journal articles hal-01537840v1

Moving through the gate in ATP-activated P2X receptors

Ruotian Jiang , Antoine Taly , Thomas Grutter
Trends in Biochemical Sciences, 2013, 38 (1), pp.20--29
Journal articles hal-01498063v1

Optical control of an ion channel gate

Damien Lemoine , Chloé Habermacher , Adeline Martz , P. F. Mery , Nathalie Bouquier et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (51), pp.20813--20818. ⟨10.1073/pnas.1318715110⟩
Journal articles hal-01498069v1

Agonist-dependent Endocytosis of γ-Aminobutyric Acid Type A (GABAA) Receptors Revealed by a γ2(R43Q) Epilepsy Mutation.

Severine Chaumont , Caroline André , David Perrais , Eric Boué-Grabot , Antoine Taly et al.
Journal of Biological Chemistry, 2013, 288 (39), pp.28254-28265. ⟨10.1074/jbc.M113.470807⟩
Journal articles hal-01146637v1

Novel approaches to drug design for the treatment of schizophrenia

Antoine Taly
Expert Opinion on Drug Discovery, 2013, 8 (10), pp.1285--1296
Journal articles hal-01498089v1

Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain

Shujia Zhu , David Stroebel , C Andrea Yao , Antoine Taly , Pierre Paoletti et al.
Nature Structural and Molecular Biology, 2013, 20 (4), pp.477--485
Journal articles hal-01498074v1

α7 nicotinic acetylcholine receptors: a therapeutic target in the structure era

Antoine Taly , Sébastien Charon
Current Drug Targets, 2012, 13 (5), pp.695--706
Journal articles hal-01498121v1

α7-Nicotinic acetylcholine receptors: an old actor for new different roles

P. Russo , Antoine Taly
Current Drug Targets, 2012, 13 (5), pp.574--578
Journal articles hal-01498100v1
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Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor

Éva Lörinczi , Yogesh Bhargava , Stephen Marino , Antoine Taly , Karina Kaczmarek-Hájek et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (28), pp.11396-11401. ⟨10.1073/pnas.1118759109⟩
Journal articles hal-02306930v1

Ligand-gated ion channels: new insights into neurological disorders and ligand recognition

Damien Lemoine , Ruotian Jiang , Antoine Taly , Thierry Chataigneau , Alexandre Specht et al.
Chem. Rev., 2012, 112 (12), pp.6285--6318
Journal articles hal-01498103v1
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From Toxins Targeting Ligand Gated Ion Channels to Therapeutic Molecules

Adak Nasiripourdori , Valérie Taly , Thomas Grutter , Antoine Taly
Toxins, 2011, 3 (3), pp.260-293. ⟨10.3390/toxins3030260⟩
Journal articles inserm-02299586v1
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Discrimination of agonists versus antagonists of nicotinic ligands based on docking onto AChBP structures.

Antoine Taly , Claire Colas , Thérèse Malliavin , Arnaud Blondel , Michael Nilges et al.
Journal of Molecular Graphics and Modelling, 2011, 30, pp.100-9. ⟨10.1016/j.jmgm.2011.06.008⟩
Journal articles pasteur-01459822v1
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The HSP90 binding mode of a radicicol-like -oxime from docking, binding free energy estimations, and NMR N chemical shifts

Martin Spichty , Antoine Taly , Franz Hagn , Horst Kessler , Sofia Barluenga et al.
Biophysical Chemistry, 2009, 143 (3), pp.111. ⟨10.1016/j.bpc.2009.04.003⟩
Journal articles hal-00545277v1

Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

Antoine Taly , Pierre-Jean Corringer , Denis Guedin , Pierre Lestage , Jean-Pierre Changeux et al.
Nature Reviews Drug Discovery, 2009, 8 (9), pp.733-750. ⟨10.1038/nrd2927⟩
Journal articles pasteur-02542745v1

A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family.

Nicolas Bocquet , Lia Prado de Carvalho , Jean Cartaud , Jacques Neyton , Chantal Le Poupon et al.
Nature, 2007, 445 (7123), pp.116-9. ⟨10.1038/nature05371⟩
Journal articles hal-00122527v1

Identification of two critical residues within the Cys-loop sequence that determine fast-gating kinetics in a pentameric ligand-gated ion channel

Thomas Grutter , Lia Prado de Carvalho , Virginie Dufresne , Antoine Taly , Jean-Pierre Changeux et al.
Journal of Molecular Neuroscience, 2006, 30(1-2), pp.63-4. ⟨10.1385/JMN:30:1:63⟩
Journal articles pasteur-00161361v1

Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors.

Antoine Taly , Pierre-Jean Corringer , Thomas Grutter , Lia Prado de Carvalho , Martin Karplus et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (45), pp.16965-70. ⟨10.1073/pnas.0607477103⟩
Journal articles pasteur-00161366v1

A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels

Thomas Grutter , Lia Prado de Carvalho , Virginie Dufresne , Antoine Taly , Markus Fischer et al.
Comptes Rendus Biologies, 2005, 328 (3), pp.223-34. ⟨10.1016/j.crvi.2004.11.004⟩
Journal articles pasteur-00162535v1

Molecular tuning of fast gating in pentameric ligand-gated ion channels.

Thomas Grutter , Lia Prado de Carvalho , Virginie Dufresne , Antoine Taly , S. Edelstein et al.
Proceedings of the National Academy of Sciences of the United States of America, 2005, 102 (50), pp.18207-12. ⟨10.1073/pnas.0509024102⟩
Journal articles pasteur-00162528v1

Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism.

Antoine Taly , Marc Delarue , Thomas Grutter , Michael Nilges , Nicolas Le Novere et al.
Biophysical Journal, 2005, 88 (6), pp.3954-65. ⟨10.1529/biophysj.104.050229⟩
Journal articles pasteur-00162514v1
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Assistant en accessibilité, rendre accessible une activité d'analyse d'article

Gérard Uzan , Alexis Culpin , Estelle Dupré , Juliette Gaëtan , Antoine Taly et al.
12ième édition Conférence Handicap 2022, Jun 2022, Paris, France. pp.161-166
Conference papers hal-03769787v1
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The Colectyng Model for the Evaluation of Game-Based Learning Activities

Antoine Taly , Damien Djaouti , Julian Alvarez
International Conference on Games and Learning Alliance, Dec 2020, Laval, France. pp.401-407, ⟨10.1007/978-3-030-63464-3_38⟩
Conference papers hal-03381221v1
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Is the Boundary of Fun Redefined in a Mixed-Reality Serious Game?

Antoine Taly
8th International Toy Research Association World Conference, International Toy Research Association (ITRA), Jul 2018, Paris, France
Conference papers hal-02081028v1

Optogating a powerful approach to control an ion-channel gate

Damien Lemoine , Chloé Habermacher , Adeline Martz , Pierre-François Méry , Nathalie Bouquier et al.
PURINERGIC SIGNALLING, 2014, Unknown, Unknown Region. pp.762--762
Conference papers hal-01498038v1
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Serious Games for Vocational Training: From Emotional Labor to Knowledge Transfer

Lydia Martin , Julian Alvarez , Antoine Taly
Marc-Eric Bobillier Chaumon. Digital Transformations in the Challenge of Activity and Work, Wiley; ISTE, 2021, ⟨10.1002/9781119808343.ch5⟩
Book sections hal-03381218v1

Design Games and Game Design: Relations Between Design, Codesign and Serious Games in Adult Education

Julian Alvarez , Olivier Irrmann , Damien Djaouti , Antoine Taly , Olivier Rampnoux et al.
From UXD to LivXD, John Wiley & Sons, Inc., pp.229-253, 2019, ⟨10.1002/9781119612254.ch11⟩
Book sections hal-02345061v1

Étude préliminaire sur les relations entre le design et le jeu sérieux dans le cadre de la formation pour adulte

Julian Alvarez , Olivier Irrmann , Antoine Taly , Damien Djaouti , Olivier Rampnoux et al.
Sylvie Leleu-Merviel; Daniel Schmitt; Philippe Useille. De l'UXD au LivXD, le design des expériences de vie, Iste Editions, pp.253-278, 2018, Sciences, société et nouvelles technologies, ISBN : 9781784055240 (papier); ISBN : 9781784065249 (ebook)
Book sections hal-02533874v1

Foundations of Biomolecular Simulations: A Critical Introduction to Homology Modeling, Molecular Dynamics Simulations, and Free Energy Calculations of Membrane Proteins

Jérôme Hénin , Marc Baaden , Antoine Taly
Membrane Proteins Production for Structural Analysis, Springer New York, pp.347--392, 2014, 978-1-4939-0661-1. ⟨10.1007/978-1-4939-0662-8_13⟩
Book sections hal-01498051v1
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Relation structure-fonction de protéines membranaires : de l'expérience à la modélisation et vice-versa

Antoine Taly
Biophysique. Université Paris Diderot - Paris 7- Sorbonne Paris Cité, 2012
Habilitation à diriger des recherches tel-01549673v1