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Armelle BAEZA

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Professor of cell biology, environmental toxicology at the University of Paris. Working for many years on the toxicity of inhaled particles (fine particles, ultrafine particles, manufactured nanoparticles) with a focus on in vitro approaches. Development of advanced culture models of bronchial and alveolar epithelia. Research aims to identify the mechanisms of action of particles (uptake, oxidative stress, pro-inflammatory response) and the physico-chemical determinants of particles involved in their effects.


Effects of brake wear nanoparticles on the protection and repair functions of the airway epithelium

Chloé Puisney-Dakhli , Evdokia Oikonomou , Mickaël Tharaud , Yann Sivry , Jean-François Berret
Environmental Pollution, 2023, 327, pp.121554. ⟨10.1016/j.envpol.2023.121554⟩
Journal articles hal-04076957v1
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Long-term evolution of the epithelial cell secretome in preclinical 3D models of the human bronchial epithelium

Daniel Sanchez-Guzman , Sonja Boland , Oliver Brookes , Claire Mc Cord , René Lai Kuen
Scientific Reports, 2021, 11, pp.6621. ⟨10.1038/s41598-021-86037-0⟩
Journal articles hal-03178798v1
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Alveolar mimics with periodic strain and its effect on the cell layer formation

Milad Radiom , Yong He , Juan Peng , Armelle Baeza-Squiban , Jean-François Berret
Biotechnology and Bioengineering, 2020, 117 (9), pp.2827-2841. ⟨10.1002/bit.27458⟩
Journal articles hal-02868726v1
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In Situ Analysis of Weakly Bound Proteins Reveals Molecular Basis of Soft Corona Formation

Daniel Sanchez-Guzman , Gaël Giraudon--Colas , Laurent Marichal , Yves Boulard , Frank Wien
ACS Nano, 2020, 17, pp.9073-9088. ⟨10.1021/acsnano.0c04165⟩
Journal articles cea-02894519v1
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Lung antioxidant depletion: a predictive indicator of cellular stress induced by ambient fine particles

Bélinda Crobeddu , Isabelle Baudrimont , Juliette Deweirdt , Jean Sciare , Anne Badel
Environmental Science and Technology, 2020, 54 (4), pp.2360-2369. ⟨10.1021/acs.est.9b05990⟩
Journal articles hal-03227888v1
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Physico-chemical characterization of urban aerosols from specific combustion sources in West Africaat Abidjan in Côte d’Ivoire and Cotonou in Benin in the frame of DACCIWA program

Aka Jacques Adon , Catherine Liousse , Elhadji Thierno Doumbia , Armelle Baeza-Squiban , Hélène Cachier
Atmospheric Chemistry and Physics, 2020, 20, pp.5327-5354. ⟨10.5194/acp-20-5327-2020⟩
Journal articles hal-02409995v1
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Aerosol characterisation including oxidative potential as a proxy of health impact: A case of a residential site in a highly industrialised area

Josipovic Miroslav , Catherine Leal-Liousse , Bélinda Crobeddu , Armelle Baeza-Squiban , Segakweng C. Keitumetse
The Clean Air Journal, 2019, ⟨10.17159/2410-972X/2019/v29n2a1⟩
Journal articles hal-02409811v1
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Aerosol characterisation including oxidative potential as a proxy of health impact

Miroslav Josipovic , Belinda Crobeddu , Catherine Leal-Liousse , Armelle Baeza-Squiban , C Keitumetse Segakweng
The Clean Air Journal, 2019, 29, ⟨10.17159/caj/2019/29/2.7517⟩
Journal articles hal-03041629v1
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Brake wear (nano)particle characterization and toxicity on airway epithelial cells in vitro

Chloé Puisney , Evdokia K Oikonomou , Sophie Nowak , Alexandre Chevillot , Sandra Casale
Environmental science‎.Nano, 2018, 5 (4), pp.1036-1044. ⟨10.1039/C7EN00825B⟩
Journal articles hal-02342487v1
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Supported pulmonary surfactant bilayers on silica nanoparticles: formulation, stability and impact on lung epithelial cells

Fanny Mousseau , Chloé Puisney , Stéphane Mornet , Rémi Le Borgne , Annie Vacher
Nanoscale, 2017, 9 (39), pp.14967-14978. ⟨10.1039/c7nr04574c⟩
Journal articles hal-02342489v1
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Vers une mesure du potentiel oxydant des particules fines

Armelle Baeza-Squiban
Les cahiers de la Recherche : Santé, Environnement, Travail, 2016, Santé et pollution atmosphérique, 7, pp.35-37
Journal articles anses-01765212v1

Pollution de l’air des enceintes ferroviaires souterraines et risques sanitaires chez les travailleurs

Matteo Redaelli , Nathalie Bonvallot , Bénédicte Clin-Godard , Christophe Debert , Guillaume Garçon
Archives des Maladies Professionnelles et de L'Environnement, 2016, 34e Congrès National de Médecine et Santé au Travail, 77 (3), pp.548. ⟨10.1016/j.admp.2016.03.448⟩
Journal articles hal-01331986v1
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Metallic oxide nanoparticle translocation across the human bronchial epithelial barrier.

Isabelle George , Grégoire Naudin , Sonja Boland , Stéphane Mornet , Vincent Contremoulins
Nanoscale, 2015, 7 (10), pp.4529-4544. ⟨10.1039/c4nr07079h⟩
Journal articles hal-01228101v1
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Acute exposure to silica nanoparticles enhances mortality and increases lung permeability in a mouse model of Pseudomonas aeruginosa pneumonia.

Mathilde Delaval , Sonja Boland , Brigitte Solhonne , Marie-Anne Nicola , Stéphane Mornet
Particle and Fibre Toxicology, 2014, 12 (1), pp.1. ⟨10.1186/s12989-014-0078-9⟩
Journal articles inserm-01264515v1

Environmental and health impacts of fine and ultrafine metallic particles: Assessment of threat scores

Sylvaine Goix , Thibaut Lévèque , Tian-Tian Xiong , Eva Schreck , Armelle Baeza-Squiban
Environmental Research, 2014, 133, pp.185-194. ⟨10.1016/j.envres.2014.05.015⟩
Journal articles hal-02419819v1

Particle size distributions of currently used pesticides in a rural atmosphere of France

Clara Coscollà , Abderrazak Yahyaoui , Patrice Colin , Corine Robin , Laurent Martinon
Atmospheric environment, 2013, 81, pp.32-38. ⟨10.1016/j.atmosenv.2013.08.057⟩
Journal articles insu-01192777v1

Development of a repeated exposure protocol of human bronchial epithelium in vitro to study the long-term effects of atmospheric particles

Laura Boublil , Emeline Assémat , Marie-Caroline Borot , Sonja Boland , Laurent Martinon
Toxicology in Vitro, 2013, 27 (2), pp.533-542. ⟨10.1016/j.tiv.2012.11.008⟩
Journal articles hal-03207474v1
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Deciphering the mechanisms of cellular uptake of engineered nanoparticles by accurate evaluation of internalization using imaging flow cytometry.

Sandra Vranic , Nicole Boggetto , Vincent Contremoulins , Stéphane Mornet , Nora Reinhardt
Particle and Fibre Toxicology, 2013, 10, pp.2. ⟨10.1186/1743-8977-10-2⟩
Journal articles hal-00813978v1
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Physico-chemical characterization of African urban aerosols (Bamako in Mali and Dakar in Senegal) and their toxic effects in human bronchial epithelial cells: description of a worrying situation.

Stéphanie Val , Cathy Liousse , El Hadji Thierno Doumbia , Corinne Galy-Lacaux , Hélène Cachier
Particle and Fibre Toxicology, 2013, 10 (1), pp.10. ⟨10.1186/1743-8977-10-10⟩
Journal articles inserm-00818453v1
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A comparative transmission electron microscopy study of titanium dioxide and carbon black nanoparticles uptake in human lung epithelial and fibroblast cell lines.

Esther Belade , Lucie Armand , Laurent Martinon , Laurence Kheuang , Jocelyne Fleury-Feith
Toxicology in Vitro, 2012, 26 (1), pp.57-66. ⟨10.1016/j.tiv.2011.10.010⟩
Journal articles inserm-00673352v1

Role of size and composition of traffic and agricultural aerosols in the molecular responses triggered in airway epithelial cells

Val Stéphanie , Martinon Laurent , Cachier Hélène , Yahyaoui Abderrazak , Marfaing Hélène
Inhalation Toxicology, 2011, 23 (11), pp.627-640. ⟨10.3109/08958378.2011.599445⟩
Journal articles hal-03203440v1

Interactions between magnetic nanowires and living cells: uptake, toxicity, and degradation.

Malak Safi , Minhao Yan , Marie-Alice Guedeau-Boudeville , Hélène Conjeaud , Virginie Garnier-Thibaud
ACS Nano, 2011, 5 (7), pp.5354-64. ⟨10.1021/nn201121e⟩
Journal articles hal-00627695v1

Interactions between Magnetic Nanowires and Living Cells : Uptake, Toxicity and Degradation

Malak Safi , Minhao Yan , Marie-Alice Guedeau-Boudeville , Hélène Conjeaud , Virginie Garnier-Thibaud
Journal articles hal-00617085v1
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In vitro Assessment of the Pulmonary Toxicity and Gastric Availability of Lead-Rich Particles from a Lead Recycling Plant.

Gaëlle Uzu , Jean-Jacques Sauvain , Armelle Baeza-Squiban , Michael Riediker , Magdalena Sanchez
Environmental Science and Technology, 2011, 45 (18), pp.7888-7895. ⟨10.1021/es200374c⟩
Journal articles ineris-00963305v1
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Carbon black and titanium dioxide nanoparticles elicit distinct apoptotic pathways in bronchial epithelial cells.

Salik Hussain , Leen Thomassen , Ioana Ferecatu , Marie-Caroline Borot , Karine Andreau
Particle and Fibre Toxicology, 2010, 7 (1), pp.10. ⟨10.1186/1743-8977-7-10⟩
Journal articles inserm-00668461v1
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Inducible expression of beta defensins by human respiratory epithelial cells exposed to Aspergillus fumigatus organisms.

Ludmila Alekseeva , Dominique Huet , Françoise Féménia , Isabelle Mouyna , Mahdia Abdelouahab
BMC Microbiology, 2009, 9 (33), pp.33. ⟨10.1186/1471-2180-9-33⟩
Journal articles inserm-00370942v1
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Size-partitioning of an urban aerosol to identify particle determinants involved in the proinflammatory response induced in airway epithelial cells

Kiran Ramgolam , Olivier Favez , Helene Cachier , Annie Gaudichet , Francelyne Marano
Particle and Fibre Toxicology, 2009, 6 (1), pp.10. ⟨10.1186/1743-8977-6-10⟩
Journal articles hal-03199093v1

Fine urban atmospheric particulate matter modulates inflammatory gene and protein expression in human bronchial epithelial cells

Augustin Baulig , Sophie Blanchet , Melina Rumelhard , Ghislaine Lacroix , Francelyne Marano
Frontiers in Bioscience-Landmark, 2007, 12, pp.771-782
Journal articles ineris-00963062v1

Experimental models in nanotoxicology

Armelle Baeza-Squiban , Ghislaine Lacroix , Frédéric Y. Bois
LAHMANI, M. ; MARANO, F. ; HOUDY, P. Nanoethics and Nanotoxicology, Springer. Berlin, pp.63-86, 2011
Book sections ineris-00969446v1

Modèles expérimentaux en nanotoxicologie

Armelle Baeza-Squiban , Ghislaine Lacroix , Frédéric Y. Bois
LAHMANI, M. ; MARANO, F. ; HOUDY, P. Les Nanosciences Tome 4 : Nanotoxicologie et nanoéthique, Belin. Paris, pp.98-120, 2010
Book sections ineris-00969417v1