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Liver gene expression and its rewiring in hepatic steatosis are controlled by PI3Kα-dependent hepatocyte signaling
Marion Régnier
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Arnaud Polizzi
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Tiffany Fougeray
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Anne Fougerat
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Prunelle Perrier
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Article dans une revue
hal-05063626v1
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Thermoneutral housing worsens MASLD and reveals defective brown adipose tissue response to β3-adrenergic stimulation
Céline Marie Pauline Martin
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Arnaud Polizzi
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Valérie Alquier-Bacquié
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Marine Huillet
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Clémence Rives
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Article dans une revue
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Dietary Amino Acid Source Elicits Sex‐Specific Metabolic Response to Diet‐Induced NAFLD in Mice
Clémence Rives
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Céline Marie Pauline Martin
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Lauris Evariste
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Arnaud Polizzi
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Marine Huillet
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Article dans une revue
hal-04287354v1
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Continuous low-level dietary exposure to glyphosate elicits dose and sex-dependent synaptic and microglial adaptations in the rodent brain.
Noemie Cresto
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Margot Courret
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Athénaïs Génin
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Céline Marie Pauline Martin
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Julie Bourret
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Article dans une revue
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Lipid sensing by PPARα: Role in controlling hepatocyte gene regulatory networks and the metabolic response to fasting
Anne Fougerat
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Justine Bruse
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Arnaud Polizzi
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Alexandra Montagner
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Hervé Guillou
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Article dans une revue
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FGF19 and its analog Aldafermin cooperate with MYC to induce aggressive hepatocarcinogenesis
José Ursic-Bedoya
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Guillaume Desandré
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Carine Chavey
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Pauline Marie
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Arnaud Polizzi
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Article dans une revue
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FGF19 and its analog Aldafermin cooperate with MYC to induce aggressive hepatocarcinogenesis
José Ursic-Bedoya
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Guillaume Desandré
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Carine Chavey
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Pauline Marie
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Arnaud Polizzi
et al.
Article dans une revue
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The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis
Marc Schoeler
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Sandrine Ellero-Simatos
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Till Birkner
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Jordi Mayneris-Perxachs
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Lisa Olsson
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Article dans une revue
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Intestinal Pgc1α ablation protects from liver steatosis and fibrosis
Elena Piccinin
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Maria Arconzo
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Maria Laura Matrella
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Marica Cariello
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Arnaud Polizzi
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Article dans une revue
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Obesity promotes fumonisin B1 hepatotoxicity
Léonie Dopavogui
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Marion Régnier
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Arnaud Polizzi
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Quentin Ponchon
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Sarra Smati
et al.
Article dans une revue
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Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolism
Marine Huillet
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Frédéric Lasserre
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Marie‐pierre Gratacap
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Beatrice Engelmann
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Justine Bruse
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Article dans une revue
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Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor
Jean Personnaz
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Enzo Piccolo
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Alizée Dortignac
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Jason Iacovoni
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Jérôme J. Mariette
et al.
Article dans une revue
hal-03624265v1
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The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression
Tiffany Fougeray
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Arnaud Polizzi
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Marion Régnier
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Anne Fougerat
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Sandrine Ellero-Simatos
et al.
Article dans une revue
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ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity
Anne Fougerat
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Gabriele Schoiswohl
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Arnaud Polizzi
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Marion Régnier
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Carina Wagner
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Article dans une revue
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Pre- and Postnatal Dietary Exposure to a Pesticide Cocktail Disrupts Ovarian Functions in 8-Week-Old Female Mice
Léonie Dopavogui
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Florence Cadoret
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Gaspard Loison
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Sara El Fouikar
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François-Xavier Frenois
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Article dans une revue
hal-03727259v1
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Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target
Sarra Smati
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Arnaud Polizzi
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Anne Fougerat
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Sandrine Ellero-Simatos
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Yuna Blum
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Article dans une revue
hal-03215969v1
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Tissular Genomic Responses to Oral FB1 Exposure in Pigs
Léonie Dopavogui
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Arnaud Polizzi
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Anne Fougerat
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Pascal Gourbeyre
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Chloé Terciolo
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Article dans une revue
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The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice
Sharon Barretto
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Frédéric Lasserre
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Marine Huillet
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Marion Régnier
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Arnaud Polizzi
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Article dans une revue
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Endoplasmic reticulum stress controls iron metabolism through TMPRSS6 repression and hepcidin mRNA stabilization by RNA-binding protein HuR
Audrey Belot
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Ophélie Gourbeyre
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Anais Palin
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Aude Rubio
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Amélie Largounez
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Article dans une revue
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Dual regulation of TxNIP by ChREBP and FoxO1 in liver
Bénédicte Noblet
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Fadila Benhamed
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Insug O-Sullivan
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Wenwei Zhang
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Gaelle Filhoulaud
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Article dans une revue
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Dual regulation of TxNIP by ChREBP and FoxO1 in liver
Benedicte Noblet
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Fadila Benhamed
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Insug O-Sullivan
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Wenwei Zhang
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Gaëlle Filhoulaud
et al.
Article dans une revue
hal-03963490v1
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Regulation of hepatokine gene expression in response to fasting and feeding: Influence of PPARa and insulin-dependent signaling in hepatocytes
Sarra Smati
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Marion Régnier
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Tiffany Fougeray
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Arnaud Polizzi
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Anne Fougerat
et al.
Article dans une revue
hal-02402566v1
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Proton NMR enables the absolute quantification of aqueous metabolites and lipid classes in unique mouse liver samples
Aurélien Amiel
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Marie Tremblay-Franco
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Roselyne Gautier
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Simon Ducheix
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Alexandra Montagner
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Article dans une revue
hal-02622894v1
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Transcriptomic modifications of the thyroid gland upon exposure to phytosanitary-grade fipronil: Evidence for the activation of compensatory pathways
Pascal G.P. Martin
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Véronique Dupouy-Guiraute
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Julien Leghait
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Thierry Pineau
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Arnaud Polizzi
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Article dans une revue
hal-02624912v1
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Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies urinary and fecal metabolic fingerprints in C57Bl6/J mice
Lorraine Smith
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Wendy Klement
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Léonie Dopavogui
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Frédéric de Bock
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Frédéric Lasserre
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Article dans une revue
hal-02912899v1
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Author correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor
Céline Lukowicz
,
Sandrine Ellero-Simatos
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Marion Régnier
,
Fabiana Oliviero
,
Frédéric Lasserre
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Article dans une revue
hal-02627769v1
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Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity
Marion Régnier
,
Arnaud Polizzi
,
Sarra Smati
,
Céline Lukowicz
,
Anne Fougerat
et al.
Article dans une revue
inserm-02875414v1
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|
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Sphingolipid metabolism in non-alcoholic fatty liver diseases
Marion Régnier
,
Arnaud Polizzi
,
Hervé Guillou
,
Nicolas Loiseau
Article dans une revue
hal-02626541v1
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|
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Hepatic PPARα is critical in the metabolic adaptation to sepsis
Réjane Paumelle
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Joel T Haas
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Nathalie Hennuyer
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Eric Baugé
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Yann Deleye
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Article dans une revue
hal-04358206v1
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Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor
Céline Lukowicz
,
Sandrine Ellero-Simatos
,
Marion Régnier
,
Fabiana Oliviero
,
Frédéric Lasserre
et al.
Article dans une revue
hal-02428712v1
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The protective role of liver X receptor (LXR) during fumonisin B1-induced hepatotoxicity
Marion Régnier
,
Arnaud Polizzi
,
Céline Lukowicz
,
Sarra Smati
,
Frédéric Lasserre
et al.
Article dans une revue
hal-02619117v1
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Hepatic PPARalpha is critical in the metabolic adaptation to sepsis
Réjane Paumelle
,
Joël Haas
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Nathalie Hennuyer
,
Eric Baugé
,
Yann Deleye
et al.
Article dans une revue
inserm-02109735v1
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Gene expression profiling reveals that PXR activation inhibits Hhepatic PPAR alpha activity and decreases FGF21 secretion in male C57Bl6/J mice
Sharon Barretto
,
Frédéric Lasserre
,
Anne Fougerat
,
Lorraine Smith
,
Tiffany Fougeray
et al.
Article dans une revue
hal-02617929v1
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Dual extraction of mRNA and lipids from a single biological sample
Normand Podechard
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Simon Ducheix
,
Arnaud Polizzi
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Frédéric Lasserre
,
Alexandra Montagner
et al.
Article dans une revue
hal-01794296v1
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Metabolic effects of a chronic dietary exposure to a low-dose oesticide cocktail in mice: Sexual dimorphism and role of the constitutive androstane receptor
Céline Lukowicz
,
Sandrine Ellero-Simatos
,
Marion Régnier
,
Arnaud Polizzi
,
Frédéric Lasserre
et al.
Article dans une revue
hal-02624889v1
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Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling
Simon Ducheix
,
Alexandra Montagner
,
Arnaud Polizzi
,
Frédéric Lasserre
,
Marion Régnier
et al.
Article dans une revue
hal-01606929v1
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A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response
Alison Iroz
,
Alexandra Montagner
,
Fadila Benhamed
,
Françoise Levavasseur
,
Arnaud Polizzi
et al.
Article dans une revue
hal-01837159v1
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Insights into the role of hepatocyte PPARα activity in response to fasting
Marion Régnier
,
Arnaud Polizzi
,
Yannick Lippi
,
Edwin Fouché
,
Géraldine Michel
et al.
Article dans une revue
istex
hal-01605514v1
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Hepatic fasting-induced PPAR alpha activity does not depend on essential fatty acids
Arnaud Polizzi
,
Edwin Fouché
,
Simon Ducheix
,
Frédéric Lasserre
,
Alice Marmugi
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Article dans une revue
hal-01476503v1
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Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals
Alexandra Montagner
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Agata Korecka
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Arnaud Polizzi
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Yannick Lippi
,
Yuna Blum
et al.
Article dans une revue
hal-01482816v1
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Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
Alexandra Montagner
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Arnaud Polizzi
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Edwin Fouché
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Simon Ducheix
,
Yannick Lippi
et al.
Article dans une revue
inserm-02339685v1
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Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way
Alice Marmugi
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Céline Lukowicz
,
Frédéric Lasserre
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Alexandra Montagner
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Arnaud Polizzi
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Article dans une revue
hal-01837194v1
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New insights into the organ-specific adverse effects of fumonisin B1
Nicolas Loiseau
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Arnaud Polizzi
,
Aude Dupuy
,
Nicole Therville
,
Mirindra Rakotonirainy
et al.
Article dans une revue
hal-03331305v1
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Adverse effects of long-term exposure to bisphenol A during adulthood leading to hyperglycaemia and hypercholesterolemia in mice
Alice Marmugi
,
Frédéric Lasserre
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Diane Beuzelin
,
Simon Ducheix
,
Laurence Huc
et al.
Article dans une revue
istex
hal-02641668v1
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Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.
Simon Ducheix
,
Alexandra Montagner
,
Arnaud Polizzi
,
Frédéric Lasserre
,
Alice Marmugi
et al.
Article dans une revue
istex
inserm-00872314v1
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A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARα.
Simon Ducheix
,
Normand Podechard
,
Frédéric Lasserre
,
Arnaud Polizzi
,
Aurélien Pommier
et al.
Article dans une revue
istex
inserm-00872582v1
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Low Doses of Bisphenol A Induce Gene Expression Related to Lipid Synthesis and Trigger Triglyceride Accumulation in Adult Mouse Liver
Alice Marmugi
,
Simon Ducheix
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Frédéric Lasserre
,
Arnaud Polizzi
,
Alain Paris
et al.
Article dans une revue
hal-01019497v1
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Proteinase-activated receptor-4 evoked colorectal analgesia in mice: an endogenously activated feed-back loop in visceral inflammatory pain
Anita Annahazi
,
Marta-Ewa Dabek
,
K Gecse
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Christel Cartier
,
Arnaud Polizzi
et al.
Article dans une revue
hal-01228309v1
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Intracolonic infusion of fecal supernatants from ulcerative colitis patients triggers altered permeability and inflammation in mice: Role of cathepsin G and protease‐activated receptor‐4
Marta-Ewa Dabek
,
Laurent Ferrier
,
Anita Annahazi
,
Valérie Bézirard
,
Arnaud Polizzi
et al.
Article dans une revue
hal-02645072v1
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Impact of oral bisphenol A at reference doses on intestinal barrier function and sex differences after perinatal exposure in rats
Viorica Braniste
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Aurore . Jouault
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Eric Gaultier
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Arnaud Polizzi
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Claire Buisson
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Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (1), pp.448-453. ⟨10.1073/pnas.0907697107⟩
Article dans une revue
hal-01608653v1
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Effects of Illicit Dexamethasone upon Hepatic Drug Metabolizing Enzymes and Related Transcription Factors mRNAs and Their Potential Use As Biomarkers in Cattle
Mery Giantin
,
Rosa M Lopparelli
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Vanessa Zancanella
,
Pascal G.P. Martin
,
Arnaud Polizzi
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Article dans une revue
hal-02660372v1
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Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (DEHP) adult exposure in the liver using a systems biology approach
Alexandre Eveillard
,
Frédéric Lasserre
,
M de Tayrac
,
Arnaud Polizzi
,
S Claus
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Article dans une revue
istex
hal-02662270v1
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Di-(2-ethylhexyl)-phthalate (DEHP) activates the Constitutive Androstane Receptor (CAR): a novel signalling pathway sensitive to phthalates
Alexandre Eveillard
,
Laila Mselli-Lakhal
,
Ariane Mogha
,
Frédéric Lasserre
,
Arnaud Polizzi
et al.
Article dans une revue
hal-00493499v1
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