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Ata Martin LAWSON

Maître de conférences (HDR), URCOM
16
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Présentation

![](https://) Ata Martin LAWSON was born in Tsévié (Togo) in 1974. He studied at Joseph Fourier University of Grenoble, France, graduating in 2002. He worked on aurone analogs’ synthesis as potent P-gp (P-glycoprotein) inhibitors in DPM Laboratory with Pr. Ahcene Boumendjel. He also worked on flavonoid synthesis in the same laboratory. In October 2002, he moved to the University of Limoges as PhD student where he has been interested in the extraction of rotenoids and, the chemistry of natural polyphenols of the Fabaceae family. After becoming a doctor by defending his PhD in 2006, he moved to the University of Reims as an Assistant Professor in the Medicinal Chemistry Laboratory of Pr. Janos Sapi. He stayed there for two years before acquiring a permanent position as an Associate Professor at Le Havre University in 2009. He then joined the team of Pr. Adam DAÏCH at URCOM laboratory. His current research interests include natural product chemistry (phytochemistry) as well as the synthesis of novel heterocycles using chromone derivatives as starting materials following The DOS (Diversity Oriented Synthesis) strategy and finally the development of hybrid molecules synthesis with diverse biological activities. **# 1. L'axe de recherche : Axe 1. Chimie durable et Santé** **# 2. Thème de recherche** **# 3. Mots-clés** **# 4. Production Scientifique** Publications : 48 Chapitres de livre : 0 Conférences invitées : 15 .

Domaines de recherche

Chimie organique Chimie thérapeutique

Compétences

Synthèse organique Réactions domino Extraction et modification de produits naturels Synthèse de molécules hybrides Activité anticancer, antibactérienne, antibiofilm et antifongique

Publications

"sebastien-comesse"

Bi(OTf) 3 -Catalysed Access to 2,3-Substituted Isoindolinones and Tricyclic N,O-Acetals by Trapping of Bis- N -Acyliminium Species in a Tandem Process

Ahmed Aliyenne , Frédéric Pin , Vijaykumar Nimbarte , Ata Martin Lawson , Sébastien Comesse
European Journal of Organic Chemistry, 2016, 2016 (21), pp.3592-3602. ⟨10.1002/ejoc.201600530⟩
Article dans une revue hal-01928678v1

Highly Stereoselective Domino Oxa-Michael/Aza-Michael/Cyclization Synthesis of Bicyclic Lactams and Spirooxindole Skeleton

R. Le Goff , M. Sanselme , Ata Martin Lawson , Adam Daïch , Sébastien Comesse
European Journal of Organic Chemistry, 2015, 2015 (33), pp.7244-7248. ⟨10.1002/ejoc.201501072⟩
Article dans une revue hal-02413286v1

Expeditious Synthesis of the Topoisomerase I Inhibitors Isoindolo[2,1-b]isoquinolin-7(5H)-one and the Alkaloid Rosettacin Based on Aryl Radical Cyclization of Enamide Generated by Using N-Acyl­iminium Chemistry

Ata Martin Lawson , Lahssen El Blidi , Aurélie Namoune , Alexandre Bridoux , Vijaykumar Nimbarte
Synthesis: Journal of Synthetic Organic Chemistry, 2015, 47 (22), pp.3583-3592. ⟨10.1055/s-0034-1378811⟩
Article dans une revue hal-02332633v1

Simple Access to Highly Functional Bicyclic γ- and δ-Lactams: Origins of Chirality Transfer to Contiguous Tertiary/Quaternary Stereocenters Assessed by DFT

Ronan Le goff , Arnaud Martel , Morgane Sanselme , Ata Martin Lawson , Adam Daïch
Chemistry - A European Journal, 2015, 21 (7), pp.2966 - 2979. ⟨10.1002/chem.201405094⟩
Article dans une revue hal-01929393v1

A versatile domino process for the synthesis of substituted 3-aminomethylene-chromanones and 2-pyridones catalyzed by CsF

Catalin Pintiala , Ata Martin Lawson , Sébastien Comesse , Adam Daïch
Tetrahedron Letters, 2013, 54 (22), pp.2853-2857. ⟨10.1016/j.tetlet.2013.03.096⟩
Article dans une revue hal-02564869v1

Tandem aza-Michael/spiro-ring closure sequence: access to a versatile scaffold and total synthesis of (±)-coerulescine

Meral Görmen , Ronan Le Goff , Ata Martin Lawson , Adam Daïch , Sébastien Comesse
Tetrahedron Letters, 2013, 54 (17), pp.2174-2176. ⟨10.1016/j.tetlet.2013.02.047⟩
Article dans une revue hal-02564870v1

Synthesis of highly functionalized pyrrolidines as tunable templates for the direct access to (±)-coerulescine and the tricyclic core of martinellines

Ronan Le Goff , Ata Martin Lawson , Adam Daïch , Sébastien Comesse
Organic & Biomolecular Chemistry, 2013, 11 (11), pp.1818. ⟨10.1039/c3ob27472a⟩
Article dans une revue hal-02332622v1

Design, Synthesis and Development of Novel Pathways to Functionalized Azaindole-based Derivatives with Anticancer and Anti-Angiogenic Activities

Adam Daïch , Vijaykumar D. Nimbarte , Ata Martin Lawson , Sébastien Comesse
IS:CE Chem and AI-Chem Channel Autumn School 2014, Sep 2014, Southampton, United Kingdom
Communication dans un congrès hal-02568189v1

New approaches for the synthesis and functionalization of 7- and 5-azaindoles as promising templates for medicinal chemistry

Adam Daïch , F Aubertein , Ata Martin Lawson , Sébastien Comesse
IS:CE Chem and AI-Chem Channel Autumn School 2014, Apr 2014, Southampton, United Kingdom
Communication dans un congrès hal-02568188v1

“Formation de liaisons C-C et/ou C-O intramoléculaire sur les 2-pyridones : synthèse d'hétérocycle d'intérêt

Adam Daïch , Catalin Pintiala , Ata Martin Lawson , Sébastien Comesse
Journées Nord-Ouest Européennes de Chimie (JNOEC), Jun 2013, Le Havre, France
Communication dans un congrès hal-02568038v1

New synthetic scalfolds through unexpected 1-6-Aza Michael addition to chromone derivatives : application to aromathecins analogues synthesis

Adam Daïch , Catalin Pintiala , Ata Martin Lawson , Sébastien Comesse
Colloque Franco-Roumain de Chimie Médicinale (CoFRROCM), Oct 2012, Lasi, Romania
Communication dans un congrès hal-02568184v1

1-6-Aza Michael addition to chromone derivatives and their application in the synthesis of aromathecin analogues

Adam Daïch , Catalin Pintiala , Ata Martin Lawson , Sébastien Comesse
11th Anglo-Norman Organic Chemistry Colloquium (ANORCQ XI), Apr 2012, Caen, France
Communication dans un congrès hal-02568183v1

Nouvelle voie d'accès à des bislactames de type Meyer par réaction Domino

Adam Daïch , Ronan Legoff , Ata Martin Lawson , Sébastien Comesse
Journées Nord-Ouest Européennes de Chimie (JNOEC), Jun 2012, Villeneuve d'Ascq, France
Communication dans un congrès hal-02568036v1

-unsaturated diester chromone in domino process based on a 1-6-Aza Michael addition”

Adam Daïch , Catalin Pintiala , Ata Martin Lawson , Sébastien Comesse
IS:CE CHEM Summer School, Jun 2011, Norwich, United Kingdom
Communication dans un congrès hal-02568182v1

Investigations on the Domino N-Amidoacylation/Aldol Type Condensation for the Synthesis of the Bioactive Aromathecins and Analogs

Adam Daïch , A Anamoune , Ata Martin Lawson , Sébastien Comesse
Ninth Anglo-Normand Organic Chemistry Colloquium -ANORCQ X-, Apr 2010, Southampton, United Kingdom
Communication dans un congrès hal-02568177v1

Investigations on the Domino N-Amidoacylation/Aldol Type Condensation for the Synthesis of the Bioactive Aromathecins and Analogs

Adam Daïch , A Anamoune , Ata Martin Lawson , Sébastien Comesse
Journée de l'École Doctorale Normande de Chimie, Haute Normandie, Jun 2010, Caen, France
Communication dans un congrès hal-02567961v1