Badreddine Douzi

Badreddine Douzi
54
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Publications

Image document

Elucidating assembly and function of VirB8 cell wall subunits refines the DNA translocation model in Gram-positive T4SSs

Robine Maffo-Woulefack , Abbas Mohamad Ali , Haifa Laroussi , Julien Cappele , Felipe Romero-Saavedra et al.
Science Advances , 2025, ⟨10.1126/sciadv.adq5975⟩
Article dans une revue hal-04916057 v1
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Unravelling HetC as a peptidase-based ABC exporter driving functional cell differentiation in the cyanobacterium Nostoc PCC 7120

Raphaël Rachedi , Véronique Risoul , Maryline Foglino , Yanis Aoudache , Kevin Lang et al.
Microbiology Spectrum, 2024, 12 (4), ⟨10.1128/spectrum.04058-23⟩
Article dans une revue hal-04539483 v1
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Insights into dynamics and gating properties of T2SS secretins

Brice Barbat , Badreddine Douzi , Geneviève Ball , Mathilde Tribout , Khalid El Karkouri et al.
Science Advances , 2023, 9 (40), ⟨10.1126/sciadv.adg6996⟩
Article dans une revue hal-04254401 v1

Refining the Dynamic Network of T2SS Endopilus Tip Heterocomplex Combining cw‐EPR and Nitroxide–Gd III Distance Measurements

Guillaume Gerbaud , Brice Barbat , Mathilde Tribout , Emilien Etienne , Valérie Belle et al.
ChemBioChem, 2023, 24 (15), ⟨10.1002/cbic.202300099⟩
Article dans une revue hal-04210232 v1
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Structural lessons on bacterial secretins

Brice Barbat , Badreddine Douzi , Romé Voulhoux
Biochimie, 2022, 205, pp.110-116. ⟨10.1016/j.biochi.2022.08.019⟩
Article dans une revue hal-03845257 v1
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Exploration of DNA processing features unravels novel properties of ICE conjugation in Gram-positive bacteria

Haifa Laroussi , Yanis Aoudache , Emilie Robert , Virginie Libante , Louise Thiriet et al.
Nucleic Acids Research, 2022, 50 (14), pp.8127-8142. ⟨10.1093/nar/gkac607⟩
Article dans une revue hal-03881644 v1

A new twin expands the VirB8-like protein family

Robine Maffo-Woulefack , Nathalie N. Leblond-Bourget , Badreddine Douzi
Structure, 2022, 30 (6), pp.790-792. ⟨10.1016/j.str.2022.05.004⟩
Article dans une revue hal-03994713 v1
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The crystal structure of CbpD clarifies substrate-specificity motifs in chitin-active lytic polysaccharide monooxygenases

Christopher Dade , Badreddine Douzi , Christian Cambillau , Genevieve Ball , Romé Voulhoux et al.
Acta crystallographica Section D : Structural biology [1993-..], 2022, 78 (8), pp.1064-1078. ⟨10.1107/S2059798322007033⟩
Article dans une revue hal-03739502 v1
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Structural and Biochemical Analysis of OrfG: The VirB8-like Component of the Conjugative Type IV Secretion System of ICESt3 From Streptococcus thermophilus

Julien Cappele , Abbas Mohamad Ali , Nathalie N. Leblond-Bourget , Sandrine Mathiot , Tiphaine Dhalleine et al.
Frontiers in Molecular Biosciences, 2021, 8, ⟨10.3389/fmolb.2021.642606⟩
Article dans une revue hal-03196531 v1
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Structural interactions define assembly adapter function of a type II secretion system pseudopilin

Cristian Escobar , Badreddine Douzi , Geneviève Ball , Brice Barbat , Sebastien Alphonse et al.
Structure, 2021, 29 (10), pp.1116-1127.e8. ⟨10.1016/j.str.2021.05.015⟩
Article dans une revue hal-03367306 v1
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HetL, HetR and PatS form a reaction-diffusion system to control pattern formation in the cyanobacterium Nostoc PCC 7120

Xiaomei Xu , Véronique Risoul , Deborah Byrne , Stéphanie M Champ , Badreddine Douzi et al.
Article dans une revue hal-02917356 v1
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YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli

Elsa Germain , Paul Guiraud , Deborah Byrne , Badreddine Douzi , Meriem Djendli et al.
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-13764-4⟩
Article dans une revue hal-02446175 v1
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Towards a complete structural deciphering of Type VI secretion system

van Son Nguyen , Badreddine Douzi , Eric Durand , Alain Roussel , E. Cascales et al.
Current Opinion in Structural Biology, 2018, 49, pp.77 - 84. ⟨10.1016/j.sbi.2018.01.007⟩
Article dans une revue hal-01780753 v1
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Direct interactions between the secreted effector and the T2SS components GspL and GspM reveal a new effector-sensing step during type 2 secretion

Sandra Michel-Souzy , Badreddine Douzi , Frederic Cadoret , Claire Raynaud , Loïc Quinton et al.
Journal of Biological Chemistry, 2018, 293 (50), pp.19441-19450. ⟨10.1074/jbc.RA117.001127⟩
Article dans une revue hal-01919531 v1
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Structure–Function Analysis of the C-Terminal Domain of the Type VI Secretion TssB Tail Sheath Subunit

Badreddine Douzi , Laureen Logger , Silvia Spinelli , Stephanie Blangy , Christian Cambillau et al.
Journal of Molecular Biology, 2018, 430 (3), pp.297 - 309. ⟨10.1016/j.jmb.2017.11.015⟩
Article dans une revue hal-01780748 v1
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The gp27-like Hub of VgrG Serves as Adaptor to Promote Hcp Tube Assembly

Melvin G Renault , Jordi Zamarreño Beas , Badreddine Douzi , Maïalène Chabalier , Abdelrahim Zoued et al.
Journal of Molecular Biology, 2018, 430 (18 Pt B), pp.3143-3156. ⟨10.1016/j.jmb.2018.07.018⟩
Article dans une revue hal-01847145 v1
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Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics

Badreddine Douzi , Nhung Trinh , Sandra Michel-Souzy , Aline Desmyter , Genevieve Ball et al.
mBio, 2017, 8 (5), ⟨10.1128/mBio.01185-17⟩
Article dans une revue hal-01744494 v1
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Structure and specificity of the Type VI secretion system ClpV-TssC interaction in enteroaggregative Escherichia coli

Badreddine Douzi , Yannick R Brunet , Silvia Spinelli , Valentine Lensi , Stephanie Blangy et al.
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep34405⟩
Article dans une revue hal-01780690 v1
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Priming and polymerization of a bacterial contractile tail structure. 1" 2" 17

Abdelrahim Zoued , Eric Durand , Yannick R Brunet , Silvia Spinelli , Badreddine Douzi et al.
Nature, 2016, 531 (7592), pp.59 - 63. ⟨10.1038/nature17182⟩
Article dans une revue hal-01778575 v1
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Structure–Function Analysis of the TssL Cytoplasmic Domain Reveals a New Interaction between the Type VI Secretion Baseplate and Membrane Complexes

Abdelrahim Zoued , Chloé J Cassaro , Eric Durand , Badreddine Douzi , Alexandre España et al.
Journal of Molecular Biology, 2016, 428 (22), pp.4413 - 4423. ⟨10.1016/j.jmb.2016.08.030⟩
Article dans une revue hal-01780163 v1

The Type VI Secretion TssEFGK-VgrG Phage-Like Baseplate Is Recruited to the TssJLM Membrane Complex via Multiple Contacts and Serves As Assembly Platform for Tail Tube/Sheath Polymerization

Yannick Brunet , Abdelrahim Zoued , Frédéric Boyer , Badreddine Douzi , E. Cascales
PLoS Genetics, 2015, 11 (10), pp.e1005545. ⟨10.1371/journal.pgen.1005545⟩
Article dans une revue hal-03274769 v1
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The Type VI Secretion TssEFGK-VgrG Phage-Like Baseplate Is Recruited to the TssJLM Membrane Complex via Multiple Contacts and Serves As Assembly Platform for Tail Tube/Sheath Polymerization

Yannick R Brunet , Abdelrahim Zoued , Frédéric Boyer , Badreddine Douzi , E. Cascales
PLoS Genetics, 2015, 11 (10), pp.e1005545. ⟨10.1371/journal.pgen.1005545⟩
Article dans une revue hal-01458191 v1
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Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody

van Son Nguyen , Laureen Logger , Silvia Spinelli , Aline Desmyter , Thi Thu Hang Le et al.
PLoS ONE, 2015, 10 (e0122187), pp.1-14
Article dans une revue hal-01217205 v1
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Crystal Structure and Self-Interaction of the Type VI Secretion Tail-Tube Protein from Enteroaggregative Escherichia coli

Badreddine Douzi , Silvia Spinelli , Stéphanie Blangy , Alain Roussel , Eric Durand et al.
PLoS ONE, 2014, 9 (2), pp.e86918. ⟨10.1371/journal.pone.0086918⟩
Article dans une revue hal-02091448 v1

Txc, a new type II secretion system of Pseudomonas aeruginosa strain PA7, is regulated by the TtsS/TtsR two-component system and directs specific secretion of the CbpE chitin-binding protein.

Frederic Cadoret , Geneviève Ball , Badreddine Douzi , Romé Voulhoux
Journal of Bacteriology, 2014, 196 (13), pp.2376--86. ⟨10.1128/JB.01563-14⟩
Article dans une revue hal-01458218 v1
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Crystal Structure and Self-Interaction of the Type VI Secretion Tail-Tube Protein from Enteroaggregative Escherichia coli

Badreddine Douzi , Silvia Spinelli , Stéphanie Blangy , Alain Roussel , Eric Durand et al.
PLoS ONE, 2014, 9 (2), pp.e86918. ⟨10.1371/journal.pone.0086918⟩
Article dans une revue hal-03274780 v1

Architecture and assembly of the Type VI secretion system

Abdelrahim Zoued , Yannick Brunet , Eric Durand , Marie-Stéphanie Aschtgen , Laureen Logger et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2014, 1843 (8), pp.1664-1673. ⟨10.1016/j.bbamcr.2014.03.018⟩
Article dans une revue hal-03274779 v1

Architecture and assembly of the Type VI secretion system.

Abdelrahim Zoued , Yannick R Brunet , Eric Durand , Marie-Stéphanie Aschtgen , Laureen Logger et al.
Biochim. Biophys. Acta, 2014, 1843 (8), pp.1664--73. ⟨10.1016/j.bbamcr.2014.03.018⟩
Article dans une revue hal-01458220 v1
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TssK Is a Trimeric Cytoplasmic Protein Interacting with Components of Both Phage-like and Membrane Anchoring Complexes of the Type VI Secretion System

Abdelrahim Zoued , Eric Durand , Cecilia C. Bebeacua , Yannick R Brunet , Badreddine Douzi et al.
Journal of Biological Chemistry, 2013, 288 (38), pp.27031-27041. ⟨10.1074/jbc.M113.499772⟩
Article dans une revue hal-02091435 v1
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Dissection of the TssB-TssC Interface during Type VI Secretion Sheath Complex Formation

Xiang Y. Zhang , Yannick R Brunet , Laureen Logger , Badreddine Douzi , Christian Cambillau et al.
PLoS ONE, 2013, 8 (11), pp.e81074. ⟨10.1371/journal.pone.0081074⟩
Article dans une revue hal-02091436 v1
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High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli

Hervé Nozach , Carole Fruchart-Gaillard , François Fenaille , Fabrice Beau , Oscar Pereira Ramos et al.
Microbial Cell Factories, 2013, 12, ⟨10.1186/1475-2859-12-37⟩
Article dans une revue cea-02100032 v1

On the path to uncover the bacterial type II secretion system.

Badreddine Douzi , Alain Filloux , Romé Voulhoux
Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2012, 367 (1592), pp.1059--72. ⟨10.1098/rstb.2011.0204⟩
Article dans une revue hal-01458255 v1
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Towards a structural comprehension of bacterial type VI secretion systems: characterization of the TssJ-TssM complex of an Escherichia coli pathovar

Catarina Felisberto-Rodrigues , Eric Durand , Marie-Stéphanie Aschtgen , Stephanie Blangy , Miguel Ortiz-Lombardia et al.
PLoS Pathogens, 2011, 7 (11), pp.e1002386. ⟨10.1371/journal.ppat.1002386⟩
Article dans une revue hal-01458272 v1

Structure of the minor pseudopilin XcpW from the Pseudomonas aeruginosa type II secretion system.

Laura P Franz , Badreddine Douzi , Eric Durand , David H Dyer , Romé Voulhoux et al.
Acta Crystallogr. D Biol. Crystallogr., 2011, 67 (Pt 2), pp.124--30. ⟨10.1107/S0907444910051954⟩
Article dans une revue hal-01458266 v1

Deciphering the Xcp Pseudomonas aeruginosa type II secretion machinery through multiple interactions with substrates.

Badreddine Douzi , Geneviève Ball , Christian Cambillau , Mariella Tegoni , Romé Voulhoux
Journal of Biological Chemistry, 2011, 286 (47), pp.40792--801. ⟨10.1074/jbc.M111.294843⟩
Article dans une revue hal-01458270 v1

Towards a Structural Comprehension of Bacterial Type VI Secretion Systems: Characterization of the TssJ-TssM Complex of an Escherichia coli Pathovar

Catarina Felisberto-Rodrigues , Eric Durand , Marie-Stéphanie Aschtgen , Stéphanie Blangy , Miguel Ortiz-Lombardia et al.
PLoS Pathogens, 2011, 7 (11), pp.e1002386. ⟨10.1371/journal.ppat.1002386⟩
Article dans une revue hal-03274802 v1

The Assembly Mode of the Pseudopilus: a hallmark to distinguish a novel secretion system subtype

E. Durand , S. Alphonse , Céline Brochier-Armanet , G. Ball , Badreddine Douzi et al.
Journal of Biological Chemistry, 2011, 286 (27), pp.24407-24416. ⟨10.1074/jbc.M111.234278⟩
Article dans une revue hal-02299276 v1
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D-Maurocalcine, a pharmacologically inert efficient cell-penetrating peptide analogue.

Cathy Poillot , Kaouthar Dridi , Hicham Bichraoui , Julien Pêcher , Sébastien Alphonse et al.
Journal of Biological Chemistry, 2010, 285 (44), pp.34168-80. ⟨10.1074/jbc.M110.104919⟩
Article dans une revue inserm-00587800 v1

Structure of the Pseudomonas aeruginosa XcpT pseudopilin, a major component of the type II secretion system

S. Alphonse , E. Durand , Badreddine Douzi , B. Waegele , H. Darbon et al.
Journal of Structural Biology, 2010, 169 (1), pp.75-80. ⟨10.1016/j.jsb.2009.09.003⟩
Article dans une revue hal-02667520 v1

The XcpV/GspI pseudopilin has a central role in the assembly of a quaternary complex within the T2SS pseudopilus

Badreddine Douzi , E. Durand , C. Bernard , S. Alphonse , C. Cambillau et al.
Journal of Biological Chemistry, 2009, 284 (50), pp.34580-34589. ⟨10.1074/jbc.M109.042366⟩
Article dans une revue hal-02666049 v1
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Deciphering the structural organization of OrfG, the VirB8-like of ICESt3 Type IV secretion system (T4SS)

Badreddine Douzi
FEBS2023, Jul 2023, Tours, France
Poster de conférence hal-04223319 v1
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Self-assembly of XcpQ secretin N domain into hexamer of dimers provides new molecular insights into architecture and dynamics of widespread outer membrane channels

Badreddine Douzi , Romé Voulhoux , - Nhung. T. T. Trinh , - Sandra Michel-Souzy , Aline Desmyter et al.
New Approaches and Concepts in Microbiology, Jun 2017, Heidelberg, Germany. , 2017
Poster de conférence hal-02737898 v1
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Minor pseudopilins of the type II secretion system in P. aeruginosa: placing pieces in a large puzzle

Badreddine Douzi , Romé Voulhoux , Eric Durand , Loïc Quinton , Edwin de Pauw et al.
ASM Conference on Pseudomonas 2015, Sep 2015, Washington, United States. , 2015
Poster de conférence hal-02743889 v1
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Towards a better understanding of the bacterial type II secretion pathway

Badreddine Douzi , - Sandra Michel , Frédéric Cadoret , Geneviève Ball , Bérengère Ize et al.
SGM ANNUAL CONFERENCE, Apr 2014, Liverpool, United Kingdom. , 2014
Poster de conférence hal-02744249 v1
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The XcpV/GspI pseudopilin has a central role in the assembly of a quaternary complex within the T2SS pseudopilus

Badreddine Douzi , Sébastien Alphonse , Herve Darbon , Alain Filloux , Christian Cambillau et al.
Colloque de l'école doctorale Aix-Marseille, Jun 2009, Marseille, France. 1p, 2009
Poster de conférence hal-02824819 v1

Protein-Protein Interactions: Surface Plasmon Resonance

Badreddine Douzi
Bacterial Protein Secretion Systems : Methods and Protocols, Springer Link, 2017, Methods in Molecular Biology, 978-1-4939-7033-9 978-1-4939-7031-5. ⟨10.1007/978-1-4939-7033-9_21⟩
Chapitre d'ouvrage hal-02790765 v1