Bastien Gerby

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33
Documents
Affiliation actuelle
  • Centre de Recherches en Cancérologie de Toulouse (CRCT)
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Publications

Publications

GATA2 mutated allele specific expression is associated with a hyporesponsive state of HSC in GATA2 deficiency syndrome

Laetitia Largeaud , Vincent Fregona , Laura Jamrog , Camille Hamelle , Stéphanie Dufrechou et al.
Blood Cancer Journal, 2025, 15 (1), pp.7. ⟨10.1038/s41408-025-01213-z⟩
Article dans une revue hal-04953534 v1
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Stem cell–like reprogramming is required for leukemia-initiating activity in B-ALL

Vincent Fregona , Manon Bayet , Mathieu Bouttier , Laetitia Largeaud , Camille Hamelle et al.
Journal of Experimental Medicine, 2023, 221 (1), ⟨10.1084/jem.20230279⟩
Article dans une revue hal-04283055 v1
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Monoallelic Heb/Tcf12 Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia

Diogo Veiga , Mathieu Tremblay , Bastien Gerby , Sabine Herblot , André Haman et al.
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.867443⟩
Article dans une revue hal-03640336 v1

CELL QUIESCENCE AND REPROGRAMMING ARE DISTINCTIVE FEATURES OF PRE- LEUKEMIC STEM CELLS IN BACUTE LYMPHOBLASTIC LEUKEMIA

Vincent Fregona , Manon Bayet , Mathieu Bouttier , Laetitia Largeaud , Camille Hamelle et al.
Experimental Hematology, 2022, 111, pp.S86-S86. ⟨10.1016/j.exphem.2022.07.140⟩
Article dans une revue hal-03922891 v1

The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11

Bastien Gerby , Marina Lafage-Pochitaloff , Véronique Baccini , Laetitia Largeaud , Vincent Fregona et al.
Blood Advances, 2022, 6 (2), pp.386-398. ⟨10.1182/bloodadvances.2021005311⟩
Article dans une revue hal-03559295 v1

The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11

Marina Lafage-Pochitaloff , Bastien Gerby , Véronique Baccini , Laetitia Largeaud , Vincent Fregona et al.
Blood Advances, 2022, 6 (2), pp.386-398. ⟨10.1182/bloodadvances.2021005311⟩
Article dans une revue hal-04041044 v1

The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11.

Bastien Gerby , Marina Lafage-Pochitaloff , Véronique Baccini , Laetitia Largeaud , Vincent Fregona et al.
Article dans une revue hal-03376945 v1
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Germline PAX5 mutation predisposes to familial B-cell precursor acute lymphoblastic leukemia

Nicolas Duployez , Laura Jamrog , Vincent Fregona , Camille Hamelle , Laurène Fenwarth et al.
Blood, 2021, 137 (10), pp.1424-1428. ⟨10.1182/blood.2020005756⟩
Article dans une revue hal-03426713 v1
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Oncogene-Induced Reprogramming in Acute Lymphoblastic Leukemia: Towards Targeted Therapy of Leukemia-Initiating Cells

Vincent Fregona , Manon Bayet , Bastien Gerby
Cancers, 2021, 13 (21), pp.5511. ⟨10.3390/cancers13215511⟩
Article dans une revue hal-03420678 v1

A targetable cue in T-cell malignancy

Bastien Gerby , Trang Hoang
Blood, 2020, 135 (19), pp.1616-1617. ⟨10.1182/blood.2020005142⟩
Article dans une revue hal-02996851 v1
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PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice

Laura Jamrog , Guillaume Chemin , Vincent Fregona , Lucie Coster , Marlène Pasquet et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (41), pp.10357-10362. ⟨10.1073/pnas.1721678115⟩
Article dans une revue hal-02351122 v1
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<i>PAX5A</i> and <i>PAX5B</i> isoforms are both efficient to drive B cell differentiation

Charlotte Cresson , Sophie Péron , Laura Jamrog , Nelly Rouquié , Nais Prade et al.
Oncotarget, 2018, 9 (67), pp.32841-32854. ⟨10.18632/oncotarget.26003⟩
Article dans une revue hal-02566158 v1
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High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells

Bastien Gerby , Diogo F.T. Veiga , Jana Krosl , Sami Nourreddine , Julianne Ouellette et al.
Journal of Clinical Investigation, 2016, 126 (12), pp.4569-4584. ⟨10.1172/JCI86489⟩
Article dans une revue hal-02353313 v1
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SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells

Bastien Gerby , Cédric S. Tremblay , Mathieu Tremblay , Shanti Rojas-Sutterlin , Sabine Herblot et al.
PLoS Genetics, 2014, 10 (12), pp.e1004768. ⟨10.1371/journal.pgen.1004768⟩
Article dans une revue hal-02353324 v1
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Genetic interaction between Kit and Scl

Julien Lacombe , Gorazd Krost , Mathieu Tremblay , Bastien Gerby , Richard Martin et al.
Blood, 2013, 122 (7), pp.1150-1161. ⟨10.1182/blood-2011-01-331819⟩
Article dans une revue hal-02353626 v1
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Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models

Clarisse Thiollier , Cécile Lopez , Bastien Gerby , Cathy Ignacimouttou , Sandrine Poglio et al.
Journal of Experimental Medicine, 2012, 209 (11), pp.2017-2031. ⟨10.1084/jem.20121343⟩
Article dans une revue hal-02353632 v1
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Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL

Qiang Wen , Benjamin Goldenson , Serena j. Silver , Monica Schenone , Vlado Dancik et al.
Cell, 2012, 150 (3), pp.575-589. ⟨10.1016/j.cell.2012.06.032⟩
Article dans une revue hal-02353639 v1

Expression of CD34 and CD7 on human T-cell acute lymphoblastic leukemia discriminates functionally heterogeneous cell populations

Bastien Gerby , E Clappier , F Armstrong , C Deswarte , J Calvo et al.
Leukemia, 2011, 25 (8), pp.1249-1258. ⟨10.1038/leu.2011.93⟩
Article dans une revue hal-02353642 v1
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Comment un suppresseur de tumeur se prend au jeu de la prolifération leucémique chez l’homme

Francoise Pflumio , Sophie Kusy , Bastien Gerby , Paul-Henri Romeo
Médecine/Sciences, 2011, 27 (2), pp.142-144. ⟨10.1051/medsci/2011272142⟩
Article dans une revue hal-02353651 v1

Expression of CD34 and CD7 on human T-cell acute lymphoblastic leukemia discriminates functionally heterogeneous cell populations

Bastien Gerby , E Clappier , F Armstrong , C Deswarte , J Calvo et al.
Leukemia, 2011, 25 (8), pp.1249-1258. ⟨10.1038/leu.2011.93⟩
Article dans une revue hal-04977707 v1
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Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

Emmanuelle Clappier , Bastien Gerby , François Sigaux , Marc Delord , Farah Touzri et al.
Journal of Experimental Medicine, 2011, 208 (4), pp.653-661. ⟨10.1084/jem.20110105⟩
Article dans une revue hal-02353646 v1
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Iodination increases the activity of verapamil derivatives in reversing PGP multidrug resistance.

Régis Barattin , Bastien Gerby , Kevin Bourges , Gaëlle Hardy , Jose Olivares et al.
Anticancer Research, 2010, 30 (7), pp.2553-9
Article dans une revue hal-02353716 v1
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NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia

Sophie Kusy , Bastien Gerby , Nicolas Goardon , Nathalie Gault , Federica Ferri et al.
Journal of Experimental Medicine, 2010, 207 (10), pp.2141-2156. ⟨10.1084/jem.20100745⟩
Article dans une revue hal-02353654 v1

Optimized gene transfer into human primary leukemic T cell with NOD-SCID/leukemia-initiating cell activity

Bastien Gerby , F Armstrong , P de La Grange , H Medyouf , J Calvo et al.
Leukemia, 2010, 24 (3), pp.646-649. ⟨10.1038/leu.2009.235⟩
Article dans une revue hal-02353660 v1

NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity

Florence Armstrong , Philippe Brunet de la Grange , Bastien Gerby , Marie-Christine Rouyez , Julien Calvo et al.
Blood, 2009, 113 (8), pp.1730-1740. ⟨10.1182/blood-2008-02-138172⟩
Article dans une revue hal-04977714 v1

Optimized gene transfer into human primary leukemic T cell with NOD-SCID/leukemia-initiating cell activity

Bastien Gerby , F Armstrong , P de la Grange , H Medyouf , J Calvo et al.
Leukemia, 2009, 24 (3), pp.646-649. ⟨10.1038/leu.2009.235⟩
Article dans une revue hal-04977686 v1

NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity

Florence Armstrong , Philippe Brunet de La Grange , Bastien Gerby , Marie-Christine Rouyez , Julien Calvo et al.
Blood, 2009, 113 (8), pp.1730-1740. ⟨10.1182/blood-2008-02-138172⟩
Article dans une revue hal-02353664 v1

Mise en évidence des cellules souches leucémiques dans les LAL-T humaines et étude de l’implication des voies NOTCH, TAL1 et ERK/MAPK dans la leucémogenèse T humaine

Bastien Gerby , Florence Armstrong , Philippe Brunet de La Grange , Julien Calvo , Paula Ballerini et al.
Annales de Pathologie, 2008, 28 (1), pp.S28-S29. ⟨10.1016/j.annpat.2008.09.004⟩
Article dans une revue hal-02353662 v1

2-Arylidenedihydroindole-3-ones: Design, synthesis, and biological activity on bladder carcinoma cell lines

Bastien Gerby , Ahcene Boumendjel , Madeleine Blanc , Pierre Paul Bringuier , Pierre Champelovier et al.
Bioorganic and Medicinal Chemistry Letters, 2007, 17 (1), pp.208-213. ⟨10.1016/j.bmcl.2006.09.057⟩
Article dans une revue istex hal-02353666 v1

2-Arylidenedihydroindole-3-ones: Design, synthesis, and biological activity on bladder carcinoma cell lines

Bastien Gerby , Ahcène Boumendjel , Madeleine Blanc , Pierre Paul Bringuier , Pierre Champelovier et al.
Bioorganic and Medicinal Chemistry Letters, 2007, 17 (1), pp.208-213. ⟨10.1016/j.bmcl.2006.09.057⟩
Article dans une revue istex hal-04977699 v1

Piperazinobenzopyranones and Phenalkylaminobenzopyranones: Potent Inhibitors of Breast Cancer Resistance Protein (ABCG2)

Ahcène Boumendjel , Edwige Nicolle , Thomas Moraux , Bastien Gerby , Madeleine Blanc et al.
Journal of Medicinal Chemistry, 2005, 48 (23), pp.7275-7281. ⟨10.1021/jm050705h⟩
Article dans une revue istex hal-04977701 v1

Piperazinobenzopyranones and Phenalkylaminobenzopyranones: Potent Inhibitors of Breast Cancer Resistance Protein (ABCG2)

Ahcene Boumendjel , Edwige Nicolle , Thomas Moraux , Bastien Gerby , Madeleine Blanc et al.
Journal of Medicinal Chemistry, 2005, 48 (23), pp.7275-7281. ⟨10.1021/jm050705h⟩
Article dans une revue istex hal-02353671 v1

CELL QUIESCENCE AND REPROGRAMMING ARE DISTINCTIVE FEATURES OF PRE- LEUKEMIC STEM CELLS IN BACUTE LYMPHOBLASTIC LEUKEMIA

Vincent Fregona , Manon Bayet , Mathieu Bouttier , Laetitia Largeaud , Camille Hamelle et al.
51st Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), Sep 2022, Edinburgh, SCOTLAND, United Kingdom
Communication dans un congrès hal-04284139 v1