Bénédicte Elena-Herrmann

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Publications

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Photodynamic drug delivery for cancer therapy: Designing liposomes for light-controlled release and enhanced drug efficacy

Tristan Le Clainche , Ahmed Gamal Ali Abdelhamid , Nazareth Milagros Carigga Gutierrez , Marie-Anne Jourdain , Sofia Leo et al.

European Journal of Pharmaceutical Sciences, 2025, 213, pp.107221. ⟨10.1016/j.ejps.2025.107221⟩

Article dans une revue inserm-05273829v1
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Preventing neuropathy and improving anticancer chemotherapy with a carbazole-based compound

Lauriane Bosc , Maria Elena Pero , David Balayssac , Nathalie Jacquemot , Jordan Allard et al.

Science Advances , 2025, 11 (44), ⟨10.1126/sciadv.adw6328⟩

Article dans une revue hal-05369445v1
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NOX2 control over energy metabolism plays a role in acute myeloid leukaemia prognosis and survival

Carla Ijurko , Marta Romo-González , Clara García-Calvo , José Luis Sardina , Carmen Sánchez-Bernal et al.

Free Radical Biology and Medicine, 2023, 209, pp.18-28. ⟨10.1016/j.freeradbiomed.2023.10.013⟩

Article dans une revue hal-04268169v1
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The fate of mitochondria during platelet activation

Alexei Grichine , Shancy Jacob , Anita Eckly , Joran Villaret , Clotilde Joubert et al.

Blood Advances, 2023, 7 (20), pp.6290 - 6302. ⟨10.1182/bloodadvances.2023010423⟩

Article dans une revue hal-04268214v1
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Multi-Method Quantification of Acetyl-Coenzyme A and Further Acyl-Coenzyme A Species in Normal and Ischemic Rat Liver

Malgorzata Tokarska-Schlattner , Nour Zeaiter , Valérie Cunin , Stéphane Attia , Cécile Meunier et al.

International Journal of Molecular Sciences, 2023, 24 (19), pp.14957. ⟨10.3390/ijms241914957⟩

Article dans une revue hal-04243491v1
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Identification of Modulators of the C. elegans Aryl Hydrocarbon Receptor and Characterization of Transcriptomic and Metabolic AhR-1 Profiles

Lucie Larigot , Linh-Chi Bui , Marine de Bouvier , Ophélie Pierre , Grégory Pinon et al.

Antioxidants , 2022, 11 (5), pp.1030. ⟨10.3390/antiox11051030⟩

Article dans une revue hal-03745310v1
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Investigation of circulating metabolites associated with breast cancer risk by untargeted metabolomics: a case–control study nested within the French E3N cohort

Elodie Jobard , Laure Dossus , Laura Baglietto , Marco Fornili , Lucie Lécuyer et al.

British Journal of Cancer, 2021, 124 (10), pp.1734 - 1743. ⟨10.1038/s41416-021-01304-1⟩

Article dans une revue hal-03445426v1
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Effects of an Exercise and Nutritional Intervention on Circulating Biomarkers and Metabolomic Profiling During Adjuvant Treatment for Localized Breast Cancer: Results From the PASAPAS Feasibility Randomized Controlled Trial

Olivia Febvey-Combes , Elodie Jobard , Adrien Rossary , Vincent Pialoux , Aude-Marie Foucaut et al.

Integrative Cancer Therapies, 2021, 20, pp.153473542097766. ⟨10.1177/1534735420977666⟩

Article dans une revue hal-03445390v1
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Fast and ergonomic extraction of adherent mammalian cells for NMR-based metabolomics studies

Manhal Mili , Baptiste Panthu , Anne-Marie Madec , Marie-Agnès Berger , Gilles J P Rautureau et al.

Analytical and Bioanalytical Chemistry, 2020, 412 (22), pp.5453-5463. ⟨10.1007/s00216-020-02764-9⟩

Article dans une revue hal-03092830v1
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General Guidelines for Sample Preparation Strategies in HR-$\mu$MAS NMR-based Metabolomics of Microscopic Specimens

Covadonga Lucas-Torres , Thierry Bernard , Gaspard Huber , Patrick Berthault , Yusuke Nishiyama et al.

Metabolites, 2020, 10 (2), pp.54. ⟨10.3390/metabo10020054⟩

Article dans une revue cea-02464528v1
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Metabolomic Approaches to Study Chemical Exposure-Related Metabolism Alterations in Mammalian Cell Cultures

Aneta Balcerczyk , Christian Damblon , Bénédicte Elena-Herrmann , Baptiste Panthu , Gilles J P Rautureau

International Journal of Molecular Sciences, 2020, 21 (18), pp.6843. ⟨10.3390/ijms21186843⟩

Article dans une revue (article de synthèse) hal-03092814v1
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Multi-platform NMR Study of Pluripotent Stem Cells Unveils Complementary Metabolic Signatures towards Differentiation

Bénédicte Elena-Herrmann , Emilie Montellier , Anne Fages , Reut Bruck-Haimson , Arieh Moussaieff

Scientific Reports, 2020, 10 (1), pp.1622. ⟨10.1038/s41598-020-58377-w⟩

Article dans une revue inserm-02485572v1

Metabolomic Profiling of Body Fluids in Mouse Models Demonstrates that Nuclear Magnetic Resonance Is a Putative Diagnostic Tool for the Presence of Thyroid Hormone Receptor α1 Mutations

Houda Boumaza , Suzy S. Markossian , Baptiste Busi , Gilles J.P. Rautureau , Karine Gauthier et al.

Thyroid, 2019, 29 (9), pp.1327-1335. ⟨10.1089/thy.2018.0730⟩

Article dans une revue hal-02983685v1

Metabolic Phenotyping of Adipose-Derived Stem Cells Reveals a Unique Signature and Intrinsic Differences between Fat Pads

C. Lefevre , B. Panthu , D. Naville , S. Guibert , C. Pinteur et al.

Stem Cells International, 2019, 2019, pp.9323864. ⟨10.1155/2019/9323864⟩

Article dans une revue hal-02195229v1
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Discrimination of Escherichia coli and Shigella spp. by Nuclear Magnetic Resonance Based Metabolomic Characterization of Culture Media

Gilles Rautureau , Tony L Palama , Isabelle Canard , Caroline Mirande , Sonia Chatellier et al.

ACS Infectious Diseases, 2019, 5 (11), pp.1879-1886. ⟨10.1021/acsinfecdis.9b00199⟩

Article dans une revue hal-02324344v1

Cell-Free Protein Synthesis Enhancement from Real-Time NMR Metabolite Kinetics: Redirecting Energy Fluxes in Hybrid RRL Systems

Baptiste Panthu , Théophile Ohlmann , Johan Perrier , Uwe Schlattner , Pierre Jalinot et al.

ACS Synthetic Biology, 2018, 7 (1), pp.218-226. ⟨10.1021/acssynbio.7b00280⟩

Article dans une revue hal-01703962v1

Longitudinal serum metabolomics evaluation of trastuzumab and everolimus combination as pre-operative treatment for HER-2 positive breast cancer patients

Elodie Jobard , Olivier Tredan , Thomas Bachelot , Arnaud M. Vigneron , Céline Mahier Aït-Oukhatar et al.

Oncotarget, 2017, 8 (48), pp.83570-83584. ⟨10.18632/oncotarget.18784⟩

Article dans une revue hal-01646141v1

Evolution of Newborns’ Urinary Metabolomic Profiles According to Age and Growth

Aurélien Scalabre , Elodie Jobard , Delphine Demede , Ségolène Gaillard , Clément Pontoizeau et al.

Journal of Proteome Research, 2017, 16 (10), pp.3732-3740. ⟨10.1021/acs.jproteome.7b00421⟩

Article dans une revue hal-01646391v1

Insights on the virulence of swine respiratory tract mycoplasmas through genome-scale metabolic modeling

Mariana G. Ferrarini , Franciele M. Siqueira , Scheila G. Mucha , Tony Lionel Palama , Elodie Jobard et al.

BMC Genomics, 2016, 17 (1), pp.353. ⟨10.1186/s12864-016-2644-z⟩

Article dans une revue hal-01315893v1
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Structure elucidation of a complex CO2-based organic framework material by NMR crystallography

Julien Leclaire , Guillaume Poisson , Fabio Ziarelli , Gérard Pèpe , Frédéric Fotiadu et al.

Chemical Science, 2016, 7 (7), pp.4379-4390. ⟨10.1039/c5sc03810c⟩

Article dans une revue hal-01355480v1

Identification of bacterial species by untargeted NMR spectroscopy of the exo-metabolome

Tony Lionel Palama , I Canard , Gilles J P Rautureau , C. Mirande , S Chatellier et al.

Analyst, 2016, 141, pp.4558-4561. ⟨10.1039/C6AN00393A⟩

Article dans une revue hal-01359770v1

A Systematic Evaluation of Blood Serum and Plasma Pre-Analytics for Metabolomics Cohort Studies

Elodie Jobard , Olivier Trédan , Déborah Postoly , Fabrice André , Anne-Laure Martin et al.

International Journal of Molecular Sciences, 2016, 17 (12), pp. Article number: 2035 ⟨10.3390/ijms17122035⟩

Article dans une revue hal-01569309v1
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Metabolomic profiles of hepatocellular carcinoma in a European prospective cohort

Anne Fages , Talita Duarte-Salles , Magdalena Stepien , Pietro Ferrari , Veronika Fedirko et al.

BMC Medicine, 2015, 13 (242), ⟨10.1186/s12916-015-0462-9⟩

Article dans une revue hal-01234339v1

A serum metabolomic fingerprint of bevacizumab and temsirolimus combination as first-line treatment of metastatic renal cell carcinoma

Elodie Jobard , Ellen Blanc , Sylvie Négrier , Bernard Escudier , Gwenaëlle Gravis et al.

British Journal of Cancer, 2015, 113 (8), pp.1148-1157. ⟨10.1038/bjc.2015.322⟩

Article dans une revue hal-01234309v1

Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells

Arieh Moussaieff , Matthieu Rouleau , Daniel Kitsberg , Merav Cohen , Gahl Levy et al.

Cell Metabolism, 2015, 21 (3), pp.349-350. ⟨10.1016/j.cmet.2015.02.002⟩

Article dans une revue hal-01256018v1

A statistical framework to model the meeting-in-the-middle principle using metabolomic data: application to hepatocellular carcinoma in the EPIC study

Nada Assi , Anne Fages , Paolo Vineis , Marc Chadeau-Hyam , Magdalena Stepien et al.

Mutagenesis, 2015, pp.1-11. ⟨10.1093/mutage/gev045⟩

Article dans une revue hal-01212769v1

Metabolomics Analysis Uncovers That Dietary Restriction Buffers Metabolic Changes Associated with Aging in Caenorhabditis elegans

Clément Pontoizeau , Laurent Mouchiroud , Laurent Molin , Adeline Mergoud-Dit-Lamarche , Nicolas Dallière et al.

Journal of Proteome Research, 2014, 13 (6), pp.2910-2919. ⟨10.1021/pr5000686⟩

Article dans une revue hal-01071698v1

Downregulation of transcription factor E4F1 in hepatocarcinoma cells: HBV-dependent effects on autophagy, proliferation and metabolism.

Yayun Dai , Marie-Pierre Cros , Clément Pontoizeau , Bénédicte Elena-Herrmann , Günther K Bonn et al.

Carcinogenesis, 2014, 35 (3), pp.635-650. ⟨10.1093/carcin/bgt353⟩

Article dans une revue hal-00977528v1

Investigating sources of variability in metabolomic data in the EPIC study: the Principal Component Partial R-square (PC-PR2) method

Anne Fages , Pietro Ferrari , Stefano Monni , Laure Dossus , Anna Floegel et al.

Metabolomics, 2014, ⟨10.1007/s11306-014-0647-9⟩

Article dans une revue hal-00977571v1

Metabolic expressivity of human genetic variants: NMR metabotyping of MEN1 pathogenic mutants.

Benjamin J. Blaise , Claire Lopez , Cécile Vercherat , Annie Lacheretz-Bernigaud , Mathilde Bayet-Robert et al.

Journal of Pharmaceutical and Biomedical Analysis, 2014, 93, pp.118-124. ⟨10.1016/j.jpba.2013.09.029⟩

Article dans une revue istex hal-01071641v1

A serum nuclear magnetic resonance-based metabolomic signature of advanced metastatic human breast cancer.

Elodie Jobard , Clément Pontoizeau , Benjamin J. Blaise , Thomas Bachelot , Bénédicte Elena-Herrmann et al.

Cancer Letters, 2014, 343 (1), pp.33-41. ⟨10.1016/j.canlet.2013.09.011⟩

Article dans une revue istex hal-00977546v1

μHigh Resolution-Magic-Angle Spinning NMR Spectroscopy for Metabolic Phenotyping of Caenorhabditis elegans

Alan Wong , Xiaonan Li , Laurent Molin , Florence Solari , Bénédicte Elena-Herrmann et al.

Analytical Chemistry, 2014, 86, pp.6064−6070. ⟨10.1021/ac501208z⟩

Article dans une revue hal-01157464v1

Metabolomics-on-a-chip of hepatotoxicity induced by anticancer drug flutamide and its active metabolite hydroxyflutamide using HepG2/C3a microfluidic biochips

Leila Choucha-Snouber , Andrei Bunescu , Cécile Legallais , Céline Brochot , Marc-Emmanuel Dumas et al.

Toxicological Sciences, 2013, 132 (1), pp.8-20. ⟨10.1093/toxsci/kfs230⟩

Article dans une revue ineris-00963445v1

Batch profiling calibration for robust NMR metabonomic data analysis.

Anne Fages , Clément Pontoizeau , Elodie Jobard , Pierre Lévy , Birke Bartosch et al.

Analytical and Bioanalytical Chemistry, 2013, 405 (27), pp.8819-8827. ⟨10.1007/s00216-013-7296-0⟩

Article dans une revue istex hal-00915649v1
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NMR metabolomic approaches for plants, toxicology and medicine

Cécile Canlet , Laetitia L. Shintu , Benedicte B. Elena-Herrmann

L'Actualité Chimique, 2012, 364, pp.59-68

Article dans une revue hal-00939569v1

Metabolomics-on-a-chip and metabolic flux analysis for label-free modeling of the internal metabolism of HepG2/C3A cells

Djomangan Adama Ouattara , Jean-Matthieu Prot , Andrei Bunescu , Marc-Emmanuel Dumas , Bénédicte Elena-Herrmann et al.

Molecular BioSystems, 2012, 8 (7), pp.1908-1920. ⟨10.1039/c2mb25049g⟩

Article dans une revue ineris-00963393v1

La métabolomique par RMN et ses applications en biologie végétale, toxicologie et médecine

Cécile Canlet , Laetitia Shintu , Bénédicte Elena-Herrmann

L'Actualité Chimique, 2012, 346-365, pp.59-68

Article dans une revue hal-00977501v1
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Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: Application to acetaminophen injury

Jean-Matthieu Prot , Andrei Bunescu , Bénédicte Elena-Herrmann , Caroline Aninat , Leila Choucha Snouber et al.

Toxicology and Applied Pharmacology, 2012, 259 (3), pp.270-280. ⟨10.1016/j.taap.2011.12.017⟩

Article dans une revue hal-00699551v1

Metabolic profiling strategy of caenorhabditis elegans by whole-organism nuclear magnetic resonance

B. J. Blaise , J. Giacomotto , M. N. Triba , P. Toulhoat , M. Piotto et al.

Journal of Proteome Research, 2009, 8 (5), pp.2542-2550

Article dans une revue hal-00609867v1

Metabolic profiling strategy of Caenorhabditis elegans by whole-organism nuclear magnetic resonance.

Benjamin J Blaise , Jean Giacomotto , Mohamed N Triba , Pierre Toulhoat , Martial Piotto et al.

Journal of Proteome Research, 2009, 8 (5), pp.2542-50. ⟨10.1021/pr900012d⟩

Article dans une revue hal-00425221v1

Methyl Proton Contacts Obtained Using Heteronuclear Through-Bond Transfers in Solid-State NMR Spectroscopy.

A. Loquet , S. Laage , C. Gardiennet , B. Elena , L. Emsley et al.

Journal of the American Chemical Society, 2008, xxx

Article dans une revue hal-00315261v1

Two-Photon Microscopy and Spectroscopy of Lanthanide Bioprobes

Anthony d'Aléo , Guillaume Pompidor , Bénédicte Elena-Herrmann , Jean Vicat , Patrice L. Baldeck et al.

ChemPhysChem, 2007, 8 (14), pp.2125-2132. ⟨10.1002/cphc.200700375⟩

Article dans une revue istex hal-01320785v1

Metabotyping of Caenorhabditis elegans reveals latent phenotypes

Benjamin J Blaise , Jean Giacomotto , Bénédicte Elena-Herrmann , Marc-Emmanuel Dumas , Pierre Toulhoat et al.

Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (50), pp.19808-12. ⟨10.1073/pnas.0707393104⟩

Article dans une revue hal-00294039v1

Resolving Structures from Powders by NMR Crystallography Using Combined Proton Spin Diffusion and Plane Wave DFT Calculations

Chris Pickard , Elodie Salager , Guido Pintacuda , Bénédicte Elena-Herrmann , Lyndon Emsley

Journal of the American Chemical Society, 2007, 129 (29), pp.8932 - 8933. ⟨10.1021/ja071829h⟩

Article dans une revue istex hal-01889748v1

Assigning powders to crystal structures by high-resolution 1 H– 1 H double quantum and 1 H– 13 C J-INEPT solid-state NMR spectroscopy and first principles computation. A case study of penicillin G

Nicolas Mifsud , Bénédicte Elena-Herrmann , Chris Pickard , Anne Lesage , Lyndon Emsley

Physical Chemistry Chemical Physics, 2006, 8 (29), pp.3418 - 3422. ⟨10.1039/b605227d⟩

Article dans une revue istex hal-01906879v1

Molecular Structure Determination in Powders by NMR Crystallography from Proton Spin Diffusion

Bénédicte Elena-Herrmann , Guido Pintacuda , Nicolas Mifsud , Lyndon Emsley

Journal of the American Chemical Society, 2006, 128 (29), pp.9555 - 9560. ⟨10.1021/ja062353p⟩

Article dans une revue istex hal-01906209v1

Powder Crystallography by Proton Solid-State NMR Spectroscopy

Bénédicte Elena-Herrmann , Lyndon Emsley

Journal of the American Chemical Society, 2005, 127 (25), pp.9140 - 9146. ⟨10.1021/ja051208t⟩

Article dans une revue istex hal-01906908v1

Proton to carbon-13 INEPT in solid-state NMR spectroscopy.

B. Elena , A. Lesage , S. Steuernagel , A. Bockmann , L. Emsley

Journal of the American Chemical Society, 2005, 127, pp.17296-17302. ⟨10.1021/ja054411x⟩

Article dans une revue hal-00314366v1

Probing Proton−Proton Proximities in the Solid State: High-Resolution Two-Dimensional 1 H− 1 H Double-Quantum CRAMPS NMR Spectroscopy

Steven S Brown , Anne Lesage , Bénédicte Elena-Herrmann , Lyndon Emsley

Journal of the American Chemical Society, 2004, 126 (41), pp.13230 - 13231. ⟨10.1021/ja045461p⟩

Article dans une revue istex hal-01907015v1

Direct spectral optimisation of proton–proton homonuclear dipolar decoupling in solid-state NMR

Bénédicte Elena-Herrmann , Gaël de Paëpe , Lyndon Emsley

Chemical Physics Letters, 2004, 398 (4-6), pp.532 - 538. ⟨10.1016/j.cplett.2004.09.122⟩

Article dans une revue istex hal-01906946v1

Characterization of heteronuclear decoupling through proton spin dynamics in solid-state nuclear magnetic resonance spectroscopy

Gaël de Paëpe , Bénédicte Elena-Herrmann , Lyndon Emsley

The Journal of Chemical Physics, 2004, 121 (7), pp.3165 - 3180. ⟨10.1063/1.1773155⟩

Article dans une revue hal-01907024v1

Glucokinase sensitizes hepatocarcinoma cells to the lipogenic activity of fructose and controls accumulation of lipid droplets and secretion of triglyceride-rich lipoproteins

Olivier Diaz , Clémence Jacquemin , Baptiste Panthu , Bénédicte Elena-Herrmann , Gilles Rautureau et al.

International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Apr 2019, Vienna, Austria. pp.e523, ⟨10.1016/S0618-8278(19)31035-7⟩

Communication dans un congrès hal-02387598v1

Evolution of urine metabolomic profiles in newborns

Aurélien Scalabre , Elodie Jobard , Ségolène Gaillard , Bénédicte Elena-Herrmann , Pierre-Yves Mure

10èmes Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique , RFMF - Réseau Francophone de Métabolomique et Fluxomique May 2016, Montpellier, France

Communication dans un congrès hal-01575756v1

NMR investigation of targeted therapy effects on the host metabolism for HER-2 positive breast cancer

Elodie Jobard , Thomas Bachelot , Mario Campone , Olivier Trédan , Bénédicte Elena-Herrmann

10èmes Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique , RFMF - Réseau Francophone de Métabolomique et Fluxomique May 2016, Montpellier, France

Communication dans un congrès hal-01575749v1

Métabolomics

Bénédicte Elena-Herrmann

1st Joint French-Portuguese NMR conference & XXVII GERM conference, Apr 2016, Lisbon, Portugal, Portugal

Communication dans un congrès hal-01576963v1

HCV infection reprograms the hepatic glucose and glutamine metabolism

Pierre Lévy , M. Michelet , C. Brault , A. Sallé , Romain Parent et al.

International Liver Congress™ 2013 - 48th annual meeting of the European Association for the Study of the Liver (EASL)., Apr 2013, Amsterdam, Netherlands

Communication dans un congrès hal-00859842v1

Pharmaco-metabonomic investigation of acetaminophen toxicity on rat primary hepatocytes in microfluidic biochips

Claire Lopez , Mathilde Bayet-Robert , Marc-Emmanuel Dumas , Jean-Matthieu Prot , Alexandre R.R. Pery et al.

7e Journées scientifiques du Réseau Français de Métabolomique et Fluxomique (RFMF), Jun 2013, Amiens, France

Communication dans un congrès hal-00980023v1

A NMR metabonomic approach to explore early biomarkers of hepatocellular carcinoma in the european prospective investigation into cancer and nutrition (EPIC)

Anne Fages , Pietro Ferrari , Clément Pontoizeau , Veronika Fedirko , Bénédicte Elena-Herrmann et al.

International Liver Congress™ 2013 - 48th annual meeting of the European Association for the Study of the Liver (EASL)., Apr 2013, Amsterdam, Netherlands

Communication dans un congrès hal-00859827v1

Statistical recoupling of variables for the identification of candidate biomarkers and perturbed metabolic networks. Application to whole organism NMR

Benjamin J. Blaise , Cécile Vercherat , V. Navratil , Annie Lacheretz-Bernigaud , Laetitia Shintu et al.

7th International Conference of the Metabolomics Society, Jun 2011, Cairns, Australia

Communication dans un congrès hal-00980051v1

High-resolution NMR metabonomics: revealing metabolic fingerprints from whole organisms to biofluids

Bénédicte Elena-Herrmann

3ème réunion des utilisateurs du TGIR RMN très hauts champs, Nov 2011, Orléans, France

Communication dans un congrès hal-00978960v1

The impact of bacterial diet in caenorhabditis elegans NMR metabolic profiling studies

Andrei Bunescu , Kathrin Gieseler , Bénédicte Elena-Herrmann

7th International Conference of the Metabolomics Society, Jun 2011, Cairns, Australia

Communication dans un congrès hal-00980041v1

NMR Pulse Sequences for Metabolomics

Bénédicte Elena-Herrmann

Hector C. Keun. Royal Society of Chemistry, pp.22-38, 2018, NMR-based Metabolomics, 978-1-84973-643-5. ⟨10.1039/9781782627937-00022⟩

Ouvrages hal-02324338v1

Applications of Projection NMR Techniques

Torsten Herrmann , Bénédicte Elena-Herrmann

Graham A. Webb. Annual Reports on NMR Spectroscopy, Elsevier academic press inc, pp.55-102, 2013, 978-0-12-405183-6. ⟨10.1016/B978-0-12-404716-7.00002-X⟩

Chapitre d'ouvrage hal-00867696v1