carole crozet

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Lifelong exposure to polystyrene-nanoplastics induces an attention-deficit hyperactivity disorder-like phenotype and impairs brain aging in mice

Anaïs N Vignon , Gaëlle Dudon , Giulia Oliva , Steeve Thirard , Ugo G Alenda et al.
Journal of Hazardous Materials, 2025, 494, pp.138640. ⟨10.1016/j.jhazmat.2025.138640⟩
Article dans une revue hal-05387908 v1
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Generation of two isogenic-corrected control cell lines (IRMBi001-A-1; IRMBi001-A-2) from Autosomal dominant Alzheimer’s disease patient-derived iPSCs carrying a G217D mutation in presenilin 1 gene

Coralie Clua Provost , Louise Greetham , Cécile Monzo , Arnaud Monteil , Anne Rovelet-Lecrux et al.
Stem Cell Research, 2025, 87, pp.103780. ⟨10.1016/j.scr.2025.103780⟩
Article dans une revue hal-05213438 v1
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Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases

Feizhi Song , Valerija Kovac , Behnam Mohammadi , Jessica L. Littau , Franka Scharfenberg et al.
Acta Neuropathologica, 2024, 148 (1), pp.2. ⟨10.1007/s00401-024-02763-5⟩
Article dans une revue hal-04765996 v1
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Establishment of induced pluripotent stem cells IRMBi005-A from a patient with sporadic Alzheimer’s disease

C Clua Provost , L. Auboyer , Anne Rovelet-Lecrux , C. Monzo , Eliot Schob et al.
Stem Cell Research, 2023, 72, pp.103216. ⟨10.1016/j.scr.2023.103216⟩
Article dans une revue hal-04597809 v1
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Generation of induced pluripotent stem cell lines IRMBi003-A and IRMBi003-B from a healthy donor to model Alzheimer’s disease

C. Clua Provost , L. Auboyer , Anne Rovelet-Lecrux , C. Monzo , E. Schob et al.
Stem Cell Research, 2023, 73, pp.103250. ⟨10.1016/j.scr.2023.103250⟩
Article dans une revue hal-04597795 v1
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Transfer of mesenchymal stem cell mitochondria to CD4+ T cells contributes to repress Th1 differentiation by downregulating T-bet expression

Waseem Akhter , Jean Nakhle , Loïc Vaillant , Geneviève Garcin , Cécile Le Saout et al.
Stem Cell Research and Therapy, 2023, 14 (1), pp.12. ⟨10.1186/s13287-022-03219-x⟩
Article dans une revue hal-03956467 v1

Tubulin modifying enzymes as target for the treatment of tau-related diseases.

Krzysztof Rogowski , Khaled Hached , Carole Crozet , Siem van der Laan
Article dans une revue hal-04851104 v1
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Prenatal exposure to low doses of fungicides corrupts neurogenesis in neonates

Yunyun Wang , Pierre-André Lafon , Lucie Salvador-Prince , Aroa Relano Gines , Françoise Trousse et al.
Environmental Research, 2021, 195, pp.110829. ⟨10.1016/j.envres.2021.110829⟩
Article dans une revue inserm-03334138 v1
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Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases

Hélène Arnould , Vincent Baudouin , Anne Baudry , Luiz Ribeiro , Hector Ardila-Osorio et al.
PLoS Pathogens, 2021, 17 (10), pp.e1009991. ⟨10.1371/journal.ppat.1009991⟩
Article dans une revue hal-03413478 v1
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Generation of induced pluripotent stem cells (IRMBi001-A) from an Alzheimer's disease patient carrying a G217D mutation in the PSEN1 gene

L. Auboyer , C. Monzo , D. Wallon , A. Rovelet-Lecrux , A. Gabelle et al.
Stem Cell Research, 2019, 34, pp.101381. ⟨10.1016/j.scr.2018.101381⟩
Article dans une revue hal-02927150 v1
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The cellular prion protein controls the mesenchymal-like molecular subtype and predicts disease outcome in colorectal cancer

Delphine Le Corre , Alexandre Ghazi , Ralyath Balogoun , Camilla Pilati , Thomas Aparicio et al.
EBioMedicine, 2019, 46, pp.94-104. ⟨10.1016/j.ebiom.2019.07.036⟩
Article dans une revue hal-02305551 v1
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Generation of induced pluripotent stem cells (iPSCs) IRMBi002-A from an Alzheimer's disease patient carrying a D694N mutation in the APP gene

L. Auboyer , C. Monzo , D. Wallon , A. Rovelet-Lecrux , A. Gabelle et al.
Stem Cell Research, 2019, 37, pp.101438. ⟨10.1016/j.scr.2019.101438⟩
Article dans une revue hal-02863304 v1

Cell-based therapy against prion diseases

Aroa Relaño-Ginès , Sylvain Lehmann , Carole Crozet
Current Opinion in Pharmacology, 2019, 44, pp.8-14. ⟨10.1016/j.coph.2018.11.001⟩
Article dans une revue hal-02571397 v1
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How do mobile health applications support behaviour changes? A scoping review of mobile health applications relating to physical activity and eating behaviours

Olivier Aromatario , A. van Hoye , A. Vuillemin , A.-M. Foucaut , C. Crozet et al.
Public Health, 2019, 175, pp.8-18. ⟨10.1016/j.puhe.2019.06.011⟩
Article dans une revue hal-02938459 v1
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Lithium as a disease-modifying agent for prion diseases

A. Relaño-Ginés , S. Lehmann , E. Brillaud , M. Belondrade , D. Casanova et al.
Translational Psychiatry, 2018, 8, pp.163. ⟨10.1038/s41398-018-0209-4⟩
Article dans une revue hal-02315548 v1

Effect of Cooling Rates on γ → α Transformation and Metastable States in Fe–Cu Alloys with Addition of Ni

C. Crozet , M. Verdier , S. Lay , A. Antoni-Zdziobek
Metals and Materials International, 2018, 24 (4), pp.681 - 692. ⟨10.1007/s12540-018-0080-0⟩
Article dans une revue hal-01815986 v1

Prion diseases and adult neurogenesis: How do prions counteract the brain's endogenous repair machinery?

Aroa Relaño-Ginès , Sylvain Lehmann , Carole Crozet
Prion, 2014, 8 (3), pp.240-246. ⟨10.4161/pri.29021⟩
Article dans une revue hal-03171673 v1
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Systemic Delivery of siRNA Down Regulates Brain Prion Protein and Ameliorates Neuropathology in Prion Disorder

Sylvain Lehmann , Aroa Relaño-Ginès , Sarah Resina , Elsa Brillaud , Danielle Casanova et al.
PLoS ONE, 2014, 9 (2), pp.e88797. ⟨10.1371/journal.pone.0088797⟩
Article dans une revue hal-02507518 v1
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Prion replication occurs in endogenous adult neural stem cells and alters their neuronal fate: involvement of endogenous neural stem cells in prion diseases.

Aroa Relaño-Ginès , Audrey Gabelle , Claire Hamela , Maxime Belondrade , Danielle Casanova et al.
PLoS Pathogens, 2013, 9 (8), pp.e1003485. ⟨10.1371/journal.ppat.1003485⟩
Article dans une revue inserm-00854035 v1
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High Dub3 expression in mouse ESC couples the G1/S checkpoint to pluripotency

Siem van Der Laan , Nicolay Tsanov , Carole Crozet , Domenico Maiorano
Molecular Cell, 2013, 52 (3), pp.366-379. ⟨10.1016/j.molcel.2013.10.003⟩
Article dans une revue hal-00916442 v1

Influence of copper additions in Fe-10Ni (mass.%) alloys on cooling microstructures

C. Crozet , A. Antoni-Zdziobek , S. Lay , S. Coindeau
Solid State Phenomena, 2011, 172-174, pp.505-510. ⟨10.4028/www.scientific.net/SSP.172-174.505⟩
Article dans une revue hal-00692268 v1

Stem cell therapy extends incubation and survival time in prion-infected mice in a time window-dependant manner

A. Relaño-Ginés , S. Lehmann , A. Bencsik , Me Herva , Jm Torres et al.
Journal of Infectious Diseases, 2011, 204 (7), pp.1038-1045. ⟨10.1093/infdis/jir484⟩
Article dans une revue hal-00635996 v1
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Comparative proteomic analysis of human mesenchymal and embryonic stem cells: towards the definition of a mesenchymal stem cell proteomic signature

Stéphane Roche , B. Delorme , R. Oostendorp , R. Barbet , C. Caton et al.
Proteomics, 2009, 9 (2), pp.223-232. ⟨10.1002/pmic.200800035⟩
Article dans une revue hal-00357170 v1

Gene and cell therapy for prion diseases

A. Relaño-Ginés , A. Gabelle , S. Lehmann , Ollivier Milhavet , C. Crozet
Infectious Disorders - Drug Targets, 2009, 9 (1), pp.58-68. ⟨10.2174/1871526510909010058⟩
Article dans une revue hal-00367789 v1
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Cellular pathogenesis in prion diseases

C. Crozet , F. Beranger , S. Lehmann
Veterinary Research, 2008, 39 (4), pp.44. ⟨10.1051/vetres:2008021⟩
Article dans une revue hal-00275161 v1
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Cellular pathogenesis in prion diseases

Carole Crozet , Florence Beranger , Sylvain Lehmann
Veterinary Research, 2008, 39 (4), pp.1-17. ⟨10.1051/vetres:2008021⟩
Article dans une revue hal-00902924 v1
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Effective Gene Therapy in a Mouse Model of Prion Diseases

Karine Toupet , Valerie Compan , Carole Crozet , Chantal Mourton-Gilles , Nadine Mestre-Francés et al.
PLoS ONE, 2008, 3 (7), pp.e2773. ⟨10.1371/journal.pone.0002773⟩
Article dans une revue hal-01667611 v1

Trehalose impairs aggregation of PrPSc molecules and protects prion-infected cells against oxidative damage

F. Beranger , C. Crozet , A. Goldsborough , S. Lehmann
Biochemical and Biophysical Research Communications, 2008, 374 (1), pp.44-48. ⟨10.1016/j.bbrc.2008.06.094⟩
Article dans une revue istex hal-00322386 v1

Scrapie strain transmission studies in ovine PrP transgenic mice reveal dissimilar susceptibility

A. Bencsik , S. Philippe , S. Debeer , C. Crozet , D. Calavas et al.
Histochemistry and Cell Biology, 2007, 127 (5), pp.531-539. ⟨10.1007/s00418-007-0276-8⟩
Article dans une revue istex hal-00180825 v1

Les prions État des lieux 20 ans après l'apparition de l'encéphalopathie spongiforme bovine / Where do we stand 20 years after the appearance of bovine spongiform encephalopathy?

C. Crozet , S. Lehmann
Médecine/Sciences, 2007, 23 (12), pp.1148-1158. ⟨10.1051/medsci/200723121148⟩
Article dans une revue hal-00201159 v1

Peripheral circulation of the prion infectious agent in transgenic mice expressing the ovine prion protein gene in neurons only

C. Crozet , S. Lezmi , Frederic Flamant , J. Samarut , T. Baron et al.
Journal of Infectious Diseases, 2007, 195 (7), pp.997-1006. ⟨10.1086/512085⟩
Article dans une revue hal-00180826 v1

Transmission and characterization of bovine spongiform encephalopathy sources in two ovine transgenic mouse lines (TgOvPrP4 and TgOvPrP59).

C. Cordier , A. Bencsik , S. Philippe , D. Betemps , F. Ronzon et al.
Journal of General Virology, 2006, 87 (Pt 12), pp.3763-3771. ⟨10.1099/vir.0.82062-0⟩
Article dans une revue hal-00180823 v1

The truncated 23-230 form of the prion protein localizes to the nuclei of inducible cell lines independently of its nuclear localization signals and is not cytotoxic.

C. Crozet , J. Vezilier , V. Delfieu , T. Nishimura , T. Onodera et al.
Molecular and Cellular Neuroscience, 2006, 32, pp.315-323. ⟨10.1016/j.mcn.2006.05.004⟩
Article dans une revue istex hal-00113402 v1
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Inhibition of PrPSc formation by lentiviral gene transfer of PrP containing dominant negative mutations.

Carole Crozet , Yea-Lih Lin , Clément Mettling , Chantal Mourton-Gilles , Pierre Corbeau et al.
Journal of Cell Science, 2004, 117 (Pt 23), pp.5591-7. ⟨10.1242/jcs.01484⟩
Article dans une revue inserm-00143203 v1
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Anti-PrP antibodies block PrPSc replication in prion-infected cell cultures by accelerating PrPC degradation.

Véronique Perrier , Jérôme Solassol , Carole Crozet , Yveline Frobert , Chantal Mourton-Gilles et al.
Journal of Neurochemistry, 2004, 89 (2), pp.454-63. ⟨10.1111/j.1471-4159.2004.02356.x⟩
Article dans une revue inserm-00143226 v1

Molecular analysis of the protease-resistant prion protein in scrapie and bovine spongiform encephalopathy transmitted to ovine transgenic and wild-type mice

Thierry Baron , Carole Crozet , A.G. Biacabe , S. Philippe , J. Verchere et al.
Journal of Virology, 2004, 78 (12), pp.6243-6251
Article dans une revue hal-02673797 v1

Florid Plaque in ovine PrP transgenic mice infected with an experimental ovine BSE.

C. Crozet , A. Bencsik , Frederic Flamant , S. Lezmi , Jacques Samarut et al.
EMBO Reports, 2001, 21 (10), pp.952-956. ⟨10.1093/embo-reports/kve204⟩
Article dans une revue hal-00023828 v1

Efficient Transmission of Two Different Sheep Scrapie Isolates in Transgenic Mice Expressing the Ovine PrP Gene

Carole Crozet , Frederic Flamant , Anna Bencsik , Denise Aubert , Jacques Samarut et al.
Journal of Virology, 2001, 75 (11), pp.5328-5334. ⟨10.1128/JVI.75.11.5328-5334.2001⟩
Article dans une revue hal-03634581 v1

Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine PrP gene

Carole Crozet , Frederic Flamant , A. Bencsik , Denise Aubert , Jacques Samarut et al.
Journal of Virology, 2001, 75 (11), pp.5328-5334
Article dans une revue hal-02672143 v1

Human iPSC-derived microglia cells to study the role of microglia in Alzheimer's disease

Coralie Clua Provost , Carole Crozet , Hélène E. Hirbec
GDR Microglia and Inflammation, GDR Microglia and Inflammation, Oct 2024, Sète, France
Communication dans un congrès hal-04970861 v1

Modèle mixte neurones, astrocytes, microglie issus d’iPSC de patients Alzheimer

Coralie Clua Provost , Carole Crozet , Hélène E. Hirbec
8èmes journées scientifiques du CALM, CALM, Nov 2024, Montpellier (34000), France
Communication dans un congrès hal-04970897 v1

Investigating the role of Clec7a in microglia function and assessing whether it may represent an early molecular target in Alzheimer Disease (AD)

M. Prieur , Anne Laure Hemonnot-Girard , Coralie Clua Provost , Thanawat Phuadraksa , C. Crozet et al.
XVI European Meeting on Glial Cells in Health and Disease, Berlin, July 8–11, 2023, Jul 2023, Berlin, Germany. Wiley, Glia, 71 (S1), pp.T16-141C, 2023
Poster de conférence hal-04731876 v1