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Microencapsulated Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells: Optimizing 3D Culture for Tissue Engineering Applications
Marwa Hussein
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Mattia Pasqua
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Ulysse Pereira
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Nassima Benzoubir
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Jean-Charles Duclos-Vallée
Journal articles
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Generation of β-like cell subtypes from differentiated human induced pluripotent stem cells in 3D spheroids
Lisa Morisseau
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Fumiya Tokito
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Stéphane Poulain
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Valérie Plaisance
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Valerie Pawlowski
Journal articles
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Development of Liver-on-Chip Integrating a Hydroscaffold Mimicking the Liver’s Extracellular Matrix
Taha Messelmani
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Anne Le Goff
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Zied Souguir
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Victoria Maes
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Méryl Roudaut
Journal articles
hal-03861410v1
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Multiscale-Engineered Muscle Constructs: PEG Hydrogel Micro-Patterning on an Electrospun PCL Mat Functionalized with Gold Nanoparticles
Megane Beldjilali-Labro
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Rachid Jellali
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Alexander David Brown
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Alejandro Garcia Garcia
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Augustin Lerebours
Journal articles
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Validation of HepG2/C3A Cell Cultures in Cyclic Olefin Copolymer Based Microfluidic Bioreactors
Leire Etxeberria
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Taha Messelmani
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Jon Haitz Badiola
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Andreu Llobera
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Luis Fernandez
Journal articles
hal-03861408v1
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Evidence of Adult Features and Functions of Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells and Self-Organized as Organoids
Antonietta Messina
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Eléanor Luce
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Nassima Benzoubir
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Mattia Pasqua
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Ulysse Pereira
Journal articles
hal-03561619v1
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Investigation of the Exometabolomic Profiles of Rat Islets of Langerhans Cultured in Microfluidic Biochip
Amal Essaouiba
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Rachid Jellali
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Françoise Gilard
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Bertrand Gakière
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Teru Okitsu
Journal articles
hal-04213642v1
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Electrodialysis Can Lower the Environmental Impact of Hemodialysis
Ahmed Abarkan
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Nabil Grimi
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Hubert Métayer
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Tarik Sqalli Houssaïni
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C. Legallais
Journal articles
hal-03590375v1
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Monitoring mechanical stimulation for optimal tendon tissue engineering: a mechanical and biological multiscale study
Alejandro Garcia Garcia
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Jean-Baptiste Perot
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Megane Beldjilali-Labro
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Quentin Dermigny
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Marie Naudot
Journal articles
hal-03029652v1
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Cryogel-Integrated Biochip for Liver Tissue Engineering
Lilandra Boulais
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Rachid Jellali
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Ulysse Pereira
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Eric Leclerc
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Sidi A Bencherif
Journal articles
hal-03322953v1
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Preclinical characterization of alginate‐Poly‐L‐Lysine encapsulated HepaRG for extracorporeal liver supply
Mattia Pasqua
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Ulysse Pereira
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Claire Lartigue
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Jonathan Nicolas
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Pascale Vigneron
Journal articles
hal-02961888v1
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The combination of a poly‐caprolactone/nano‐hydroxyapatite honeycomb scaffold and mesenchymal stem cells promotes bone regeneration in rat calvarial defects
Marie Naudot
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Alejandro Garcia Garcia
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Nicolas Jankovsky
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Anaïs Barre
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Luciane Zabijak
Journal articles
hal-02961861v1
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Cold-to-warm machine perfusion of the liver: a novel circuit for an uninterrupted combined perfusion protocol
Claire Goumard
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Eric Savier
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Jerome Danion
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Jérôme Pelissie
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Cécile Legallais
Journal articles
hal-02884180v1
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HepaRG Self-Assembled Spheroids in Alginate Beads Meet the Clinical Needs for Bioartificial Liver
Mattia Pasqua
,
Ulysse Pereira
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Antonietta Messina
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Claire de Lartigue
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Pascale Vigneron
Journal articles
hal-02884175v1
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Development of a pancreas-liver organ-on-chip coculture model for organ-to-organ interaction studies
Amal Essaouiba
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Teru Okitsu
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R. Kinoshita
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Rachid Jellali
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Yasuyuki Sakai
Journal articles
hal-03095499v1
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Microwell-based pancreas-on-chip model enhances genes expression and functionality of rat islets of Langerhans
Amal Essaouiba
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Teru Okitsu
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Rachid Jellali
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Marie Shinohara
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Mathieu Danoy
Journal articles
hal-02884096v1
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Electrospinning of biomedically relevant gradient scaffolds: From honeycomb to randomly-oriented microstructure
Christopher Leon-Valdivieso
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Alejandro Garcia-Garcia
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Cécile Legallais
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Fahmi Bedoui
Journal articles
hal-02884169v1
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Bioartificial liver: biomechanical considerations
L. Boulais
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M. Pasqua
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C. de Lartigue
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R. Jellali
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U. Pereira
Computer Methods in Biomechanics and Biomedical Engineering, 2019, 44th Congress of the Société de Biomécanique, 22 (sup1), pp.S370-S372. ⟨10.1080/10255842.2020.1714948⟩
Journal articles
hal-03322978v1
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Nanotechnology and Bioartificial Liver Engineering. Two Rival Paths for “Converging Technology”
Xavier Guchet
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Cécile Legallais
Journal articles
hal-02140040v1
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In Vitro Bone Cell Response to Tensile Mechanical Solicitations: Is There an Optimal Protocol?
Timothée Baudequin
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Cécile Legallais
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Fahmi Bedoui
Journal articles
hal-02061207v1
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Metabolomics-on-a-chip approach to study hepatotoxicity of DDT, permethrin and their mixtures
Rachid Jellali
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Françoise Gilard
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Vittoria Pandolfi
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Audrey Legendre
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Marie-José Fleury
Journal articles
hal-02357461v1
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Bioengineering Organs for Blood Detoxification
Cécile Legallais
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Dooli Kim
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Sylvia Mihaila
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Milos Mihajlovic
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Marina Figliuzzi
Journal articles
hal-01956818v1
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Biomaterials in Tendon and Skeletal Muscle Tissue Engineering: Current Trends and Challenges
Megane Beldjilali-Labro
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Alejandro Garcia Garcia
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Firas Farhat
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Fahmi Bedoui
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Jean-François Grosset
Journal articles
hal-01956820v1
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Mass Transfers in a Fluidized Bed Bioreactor using Alginate Beads for a Future Bioartificial Liver
B. David
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E. Dore
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M.Y. Jaffrin
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C. Legallais
Journal articles
hal-02149863v1
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Poly(ε-caprolactone)/Hydroxyapatite 3D Honeycomb Scaffolds for a Cellular Microenvironment Adapted to Maxillofacial Bone Reconstruction
Alejandro Garcia Garcia
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Anne Hebraud
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Jean-Luc Duval
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Corinne Wittmer
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Ludovic Gaut
Journal articles
hal-02393845v1
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Optimizing the fluidized bed bioreactor as an external bioartificial liver
Sarah Figaro
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Ulysse Pereira
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Hiram Rada
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Nicolas Semenzato
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Dominique Pouchoulin
Journal articles
hal-02938255v1
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Alginate-Based Cell Microencapsulation for Tissue Engineering and Regenerative Medicine
Vittoria Pandolfi
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Ulysse Pereira
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Murielle Dufresne
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Cécile Legallais
Journal articles
hal-02938367v1
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Expansion properties of alginate beads as cell carrier in the fluidized bed bioartificial liver
Seyed Danial Naghib
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Vittoria Pandolfi
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Ulysse Pereira
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Rossella Girimonte
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Efrem Curcio
Journal articles
hal-02938369v1
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The Osteogenic and Tenogenic Differentiation Potential of C3H10T1/2 (Mesenchymal Stem Cell Model) Cultured on PCL/PLA Electrospun Scaffolds in the Absence of Specific Differentiation Medium
Timothée Baudequin
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Ludovic Gaut
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Marc Mueller
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Angela Huepkes
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Birgit Glasmacher
Journal articles
hal-02938374v1
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A new prescription model for regional citrate anticoagulation in therapeutic plasma exchanges
Sébastien Kissling
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Cécile Legallais
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Menno Pruijm
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Daniel Teta
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Bruno Vogt
Journal articles
hal-02938371v1
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Towards the Development and Characterization of an Easy Handling Sheet-Like Biohybrid Bone Substitute
Timothée Baudequin
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Fahmi Bedoui
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Murielle Dufresne
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Patrick Paullier
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Cécile Legallais
Journal articles
hal-03433119v1
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Comparison of two Endovascular Treatments of a Stenosed Arteriovenous Fistula: Balloon-Angioplasty with and without Stenting
Iolanda Decorato
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Zaher Kharboutly
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Cécile Legallais
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Anne-Virginie Salsac
The International Journal of Artificial Organs, 2014, 37 (10), pp.763-772
Journal articles
hal-02019770v1
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Influence of an Arterial Stenosis on the Hemodynamics Within an Arteriovenous Fistula (AVF): Comparison Before and After Balloon-Angioplasty
Iolanda Decorato
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Anne-Virginie Salsac
,
Cécile Legallais
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Mona Alimohammadi
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Vanessa Diaz-Zuccarini
Cardiovascular Engineering and Technology, 2014, 5 (3), pp.233-243
Journal articles
hal-02019623v1
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Numerical simulation of the fluid structure interactions in a compliant patient-specific arteriovenous fistula
Iolanda Decorato
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Zaher Kharboutly
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Tommaso Vassallo
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Justin Penrose
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Cécile Legallais
International Journal for Numerical Methods in Biomedical Engineering, 2014, 30 (2), pp.143-159
Journal articles
hal-02019727v1
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Metabolomics-on-a-chip of hepatotoxicity induced by anticancer drug flutamide and its active metabolite hydroxyflutamide using HepG2/C3a microfluidic biochips
Leila Choucha-Snouber
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Andrei Bunescu
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Cécile Legallais
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Céline Brochot
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Marc-Emmanuel Dumas
Journal articles
ineris-00963445v1
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Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips
Régis Baudoin
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Jean-Matthieu Prot
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Grégory Nicolas
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Jessy Brocheton
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Céline Brochot
Journal articles
ineris-00963431v1
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Impact of Alginate Composition: From Bead Mechanical Properties to Encapsulated HepG2/C3A Cell Activities for In Vivo Implantation
Stephanie Capone
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Murielle Dufresne
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Mathias Rechel
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Marie-José Fleury
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Anne-Virginie Salsac
Journal articles
hal-02019744v1
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Investigation of ifosfamide nephrotoxicity induced in a liver-kidney co-culture biochip.
Leila Choucha-Snouber
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Caroline Aninat
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Laurent Grsicom
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Geoffrey Madalinski
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Céline Brochot
Journal articles
inserm-00864839v1
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Human hepatic cell behavior on polysulfone membrane with double porosity level
Murielle Dufresne
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Patrice Bacchin
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Giulia Cerino
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Jean-Christophe Remigy
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Gerard Nathanael Adrianus
Journal articles
hal-00788387v1
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An appropriate selection of 3D alginate culture model for hepatic Huh-7 cell line encapsulation intended for viral studies
N.M. Tran
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M. Dufresne
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Gilles Duverlie
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Sandrine Castelain
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Christian Défarge
Journal articles
insu-00723045v1
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Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: Application to acetaminophen injury
Jean-Matthieu Prot
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Andrei Bunescu
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Bénédicte Elena-Herrmann
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Caroline Aninat
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Leila Choucha Snouber
Journal articles
hal-00699551v1
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Metabolomics-on-a-Chip and Predictive Systems Toxicology in Microfluidic Bioartificial Organs
Laetitia Shintu
,
Régis Baudoin
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Vincent Navratil
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Jean-Matthieu Prot
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Clément Pontoizeau
Journal articles
hal-00699575v1
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Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip.
J.M. Prot
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A.S. Briffaut
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F. Letourneur
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P. Chafey
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F. Merlier
Journal articles
hal-00637409v1
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A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening
Jean-Matthieu Prot
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Orianne Videau
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Céline Brochot
,
Cécile Legallais
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Henri Benech
Journal articles
ineris-00963290v1
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Improvement of HepG2/C3a cell functions in a microfluidic biochip.
Jean Matthieu Prot
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Caroline Aninat
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Laurent Griscom
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Florence Razan
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Céline Brochot
Journal articles
hal-00740224v1
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ENDOCOM: Implantable wireless pressure sensor for the follow-up of abdominal aortic aneurysm stented
Olivier Romain
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Johan Mazeyrat
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Patrick Garda
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Hakeim Talleb
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David Lautru
Journal articles
hal-00665334v1
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Analysis of the mass transfers in an artificial kidney microchip
A. Ould-Dris
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P. Paullier
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Laurent Griscom
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Cécile Legallais
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E. Leclerc
Journal articles
hal-00592403v1
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Prédiction de la toxicocinétique in vivo de substances chimiques à partir de données in vitro et de modèles QSAR
Dany Habka
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Alexandre R.R. Pery
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Cécile Legallais
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Céline Brochot
Environnement, Risques & Santé, 2010, 9 (6), pp.489-501
Journal articles
ineris-00963259v1
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Numerical and experimental study of blood flow through a patient-specific arteriovenous fistula used for hemodialysis
Zaher Kharboutly
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Valérie Deplano
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Eric Bertrand
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Cécile Legallais
Journal articles
hal-00429960v1
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Artificial and bioartificial liver devices: present and future.
B. Carpentier
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A. Gautier
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C. Legallais
Journal articles
hal-00437697v1
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Alginate-encapsulated HepG2 Cells in a Fluidized Bed Bioreactor Maintain Function in Human Liver Failure Plasma
Sam Coward
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Cécile Legallais
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Bertrand David
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Michael Thomas
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Ying Foo
Journal articles
hal-02149842v1
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Hollow fiber bioartificial liver: Physical and biological characterization with C3A cells.
A. Gautier
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A. Ould-Dris
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M. Dufresne
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P. Paullier
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B. von Harten
Journal of Membrane Science, 2009, 341 ((1-2)), pp.203-213
Journal articles
hal-00437709v1
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In vitro tests and modelization of bicarbonate kinetics and mass transfers during online hemodiafiltration.
H. Morel
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M.Y. Jaffrin
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P. Paullier
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C. Legallais
The International Journal of Artificial Organs, 2009, 32, pp.482-491
Journal articles
hal-00437233v1
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Les dispositifs de suppléance hépatique.
A. Gautier
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C. Legallais
Réanimation, 2009, 18 (5), pp.413-419
Journal articles
hal-00437800v1
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The place of adsorption and biochromatography in extracorporeal liver support systems.
C. Legallais
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A. Gautier
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M. Dufresne
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B. Carpentier
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R. Baudoin
Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2008, 961, pp.171-176
Journal articles
hal-00339871v1
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hree-dimensional growth of human hepatoma C3A cells within alginate beads for fluidized bioartificial liver.
A. Kinasiewicz
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A. Gautier
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D. Lewinska
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A. Smietanka
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C. Legallais
The International Journal of Artificial Organs, 2008, 31, pp.340 Â- 347
Journal articles
hal-00339867v1
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Solid–liquid mass transfers in an airlift reactor incorporating alginate beads for the application as a bioartificial liver
S. Demming
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A. Gautier
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C. Legallais
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A. Ould-Dris
Journal articles
hal-00336365v1
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Culture of C3A Cells in Alginate Beads for Fluidized Bed Bioartificial Liver.
A. Kinasiewicz
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A. Gautier
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D. Lewinska
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J. Bukowski
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C. Legallais
Journal articles
hal-00282673v1
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A theoretical study of oxygen transfer including cell necrosis for the design of a bioartificial pancreas
J.L. Dulong
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C. Legallais
Journal articles
hal-00282668v1
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Development of a renal microchip for in vitro distal tubule models.
R. Baudoin
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L. Griscom
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M. Monge
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C. Legallais
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E. Leclerc
Biotechnol. Prog, 2007, 23, pp.1245-1253
Journal articles
hal-00196149v1
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Investigations into the relationship between hemodynamics and vascular alterations in an established arteriovenous fistula.
Z. Kharboutly
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M. Fenech
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J.M. Treutenaere
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I. Claude
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C. Legallais
Medical Engineering & Physics, 2007, 29, pp.999-1007
Journal articles
hal-00282672v1
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Générateurs d'hémodialyse : état du marché français.
S. Merlo
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A. Donadey
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B. Coevoet
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C. Legallais
ITBM RBM, 2007, 28, pp.150-168
Journal articles
hal-00282676v1
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Selective control of liver and kidney cells migration during organotypic cocultures inside fibronectin-coated rectangular silicone microchannels.
E. Leclerc
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R. Baudoin
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Anne Corlu
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L. Griscom
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J.L. Duval
Biomaterials, 2007, 28, pp.1820-1829
Journal articles
hal-00172298v1
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Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity.
R. Baudoin
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Anne Corlu
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L. Griscom
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C. Legallais
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E. Leclerc
Toxicol. In vitro, 2007, 21, pp.535-544
Journal articles
hal-00172268v1
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Perfusion culture of mammalian cells in microfluidic environments for tissue engineering applications
Eric Leclerc
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Bertrand David
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Laurent Griscom
,
Bruno Lepioufle
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Yasuyuki Sakai
Journal articles
hal-02149903v1
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Perfusion culture of mammalian cells in microfluidic environments for tissue engineering applications.
E. Leclerc
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B. David
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L. Griscom
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Bruno Le Pioufle
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T. Fujii
La Houille Blanche - Revue internationale de l'eau, 2006, 3, pp.56-59
Journal articles
hal-00090259v1
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Study of Osteoblastic Cells in a Microfluidic Environment
E. Leclerc
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B. David
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L Griscom
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Bruno Le Pioufle
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T. Fujii
Biomaterials, 2006, 27 (4), pp.558-595
Journal articles
hal-00778216v1
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Mechanical properties of alginate beads hosting hepatocytes in a fluidized bed bioreactor.
B. David
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L. Barbe
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C. Legallais
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D. Barthès-Biesel
The International Journal of Artificial Organs, 2006, 29, pp.756-763
Journal articles
hal-00090597v1
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Guidance of liver and kidney organotypic cultures inside rectangular silicone microchannels.
E. Leclerc
,
A. Corlu
,
L. Griscom
,
R. Baudoin
,
C. Legallais
Biomaterials, 2006, 27, pp.4109-4119
Journal articles
hal-00090178v1
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Mechanical properties of alginate beads hosting hepatocytes in a fluidized bed bioreactor.
C David
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L. Barbe
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D. Barthès-Biesel
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C. Legallais
The International Journal of Artificial Organs, 2006, 29 (8), pp.756-63
Journal articles
hal-02149847v1
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Study of osteoblastic cells in a microfluidic environment
E. Leclerc
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B. David
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L. Griscom
,
Bruno Le Pioufle
,
T. Fujii
Journal articles
hal-02149853v1
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What are the relevant parameters for the geometrical optimization of an implantable bioartificial pancreas ?
J.L. Dulong
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C. Legallais
Journal articles
hal-00017278v1
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In vitro assessment of encapsulated C3A hepatocytes functions in a fluidized bed bioreactor
B. David
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M. M. Dufresne
,
M. Nagel
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C. Legallais
Journal articles
hal-02149856v1
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Bioartificial livers (BAL): current technological aspects and future developments
C. Legallais
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B David
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E. Dore
Journal articles
hal-02149872v1
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