Cecile Legallais

164
Documents

Présentation

Cécile LEGALLAIS

Date of birth : 07/03/1968

cecile.legallais@utc.fr

PRESENT POSITION

2018 - : Head of Laboratory of Biomechanics and Bioengineering (joint lab Université de Technologie de Compiè(UTC)/CNRS)

APPOINTMENTS

2006 - : Directeur de recherche CNRS (CNRS Senior researcher). Laboratory of Biomechanics and Bioengineering, Université de Technologie de Compiègne (FR)

2015 - 2018 :Associate Researcher (part time) Assistance Publique Hôpitaux de Paris (APHP)

1996 - 1997 : Post-doctoral Fellow, University of Calabria (Italy) & Membrana GmbH (Germany)

1993 - 2006 : Chargé de recherche CNRS (CNRS Researcher). UTC Compiègne

ACADEMIC QUALIFICATIONS

H.D.R. 1998 “Habilitation” to supervise Ph.D. Thesis. Université de Technologie de Compiègne (FR). Blood toxins removal by membrane processes.

Ph. D. 1993Université de Technologie de Compiègne (FR). Specialty : Biomedical Eng. LDL-cholesterol removal from human plasma based on cascade filtration.

MS/Eng. D 1990 Ecole Nationale Supérieure de Mécanique et Aérotechnique (Poitiers) – Engineer in Fluid Mechanics

AWARDS

Bronze Medal from the CNRS, 2003.

RESEARCH ACTIVITIES : Biomechanics of Organ Supply systems

Since 1995 : Bioartificial liver at different scales. Encapsulation of hepatoctes in alginate beads. Design and characterization of fluidized bed bioreactor. Full extracorporeal circulation. PI of ANR TecSan SUPPLIVER (2011 -2015). WP Leader RHU Ilite (Innovations in Liver tissue Engineering) (2016-2022). PI of ANR MimLiveronChip (Organ on Chip) (2019-2023)

Since 2006: Bone and musculo-skeletal tissue engineering based on stretching bioreactors – Mechanical and biological characterization.

Since 1994: Flow and Mass transfer in hemodialysis and hemodiafiltration : Collaboration with Membrana GmbH, Fresenius Medical Care, Amiens Hospital

Since 2000 : Blood flow simulations in 3D vessels reconstructed from medical images.

PUBLICATIONS and COMMUNICATIONS

- 105 papers in international journals with peer review

- 6 book chapters, 4 patents

SYNERGISTIC ACTIVITIES

- Past President (2019-2021) of European Society for Artificial Organs (ESAO). Formerly Governor (2005-2011), General Secretary (2011-2015), President Elect (2015-2017)& President (2017-2019).

- Member of the Board of the International Federation for Artificial Organs (IFAO)

- President of the XXXVIth ESAO Congress (2009) in Compiègne, France (400 participants)

- Reviewer for Artificial Organs, Journal of Membrane Science, Biotechnology Bioengineering, Separation Science and Technology, Journal of Polymer Science, Journal of Biomechanics, Medical Engineering and Physics, Plos One, Tissue Engineering, Biomaterials.

SUPERVISION

- 25 PhD students at UTC (22 achieved, 3 ongoing)

- 3 HDR Habilitation at UTC

TEACHING ACTIVITIES

- Lecture on Artificial Organs (UTC) – 20h/y

- Hands on activities for engineering students (tissue engineering, hemodialysis)

Publications

Publications

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In situ formation and culture of cell spheroids in a low-binding 3D-printed biochip

Alexandre Martins , Sylvie Klieber , Charlotte Le Graët , Eric Leclerc , Cécile Legallais et al.

Lab on a Chip, 2025, 25 (22), pp.5801-5818. ⟨10.1039/d5lc00503e⟩

Article dans une revue hal-05382340v1
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Organoids-on-chip models to mimic liver physiology

A. Brassens , A. Martins , T. Messelmani , Ulysse Pereira , J.M. Prot et al.

Multidisciplinary Biomechanics Journal, 2025, 49th congress of the Société de Biomécanique, ⟨10.46298/mbj.14576⟩

Article dans une revue hal-04738069v2
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Identification of the differential and synergic lipotoxic patterns of oleic acid, palmitic acid, and their mixture in 3D HepG2/C3A tissue using liver‐on‐chip technology

Lisa Morisseau , Valérie Pawlowski , Valérie Plaisance , Mathilde Lucas , Cécile Legallais et al.

Biotechnology Progress, In press, ⟨10.1002/btpr.70075⟩

Article dans une revue hal-05318221v1
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Inclusion of Magnesium- and Strontium-Enriched Bioactive Glass into Electrospun PCL Scaffolds for Tissue Regeneration

Francesco Gerardo Mecca , Nathália Oderich Muniz , Devis Bellucci , Cécile Legallais , Timothée Baudequin et al.

Polymers, 2025, 17 (11), pp.1555. ⟨10.3390/polym17111555⟩

Article dans une revue hal-05105726v1
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3D hepatic spheroids and liver‐organ on chip models displayed maintenance of hepatic functions and maturation profile in a long‐term culture of the humanized HepaSH cells, a human cell population harvested from chimeric mice

Hanyuan Wang , Carla Meschini , Stéphane Poulain , Soo Hyeon Kim , Hiroshi Arakawa et al.

Biotechnology Progress, 2025, ⟨10.1002/btpr.70043⟩

Article dans une revue (article de synthèse) hal-05109229v1
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Graded electrospun scaffold from aligned fibers to honeycomb micropatterns: Application to bone-tendon tissue engineering

Nicolas Rivoallan , Timothée Baudequin , Marc Mueller , Rosa Nicolas , Sara Leal Marin et al.

Biomaterials Advances, 2025, 177, pp.214413. ⟨10.1016/j.bioadv.2025.214413⟩

Article dans une revue hal-05222742v1
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Comparison of hydroxyapatite and honeycomb micro-structure in bone tissue engineering using electrospun beads-on-string fibers

Nicolas Rivoallan , Marc Mueller , Timothée Baudequin , Pascale Vigneron , Anne Hébraud et al.

The International Journal of Artificial Organs, 2024, The International Journal of Artificial Organs, Volume 47, Issue 8 Pages: 642 - 649, 47 (8), pp.642-649. ⟨10.1177/03913988241268033⟩

Article dans une revue hal-04742155v1
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3D-environment and muscle contraction regulate the heterogeneity of myonuclei

Rosa Nicolas , Marie-Ange Bonnin , Cédrine Blavet , Joana Esteves de Lima , Cécile Legallais et al.

Skeletal Muscle, 2024, 14, pp.27. ⟨10.1186/s13395-024-00359-x⟩

Article dans une revue hal-05384218v1
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Investigation of the motif activity of transcription regulators in pancreatic β-like cell subpopulations differentiated from human induced pluripotent stem cells

Eric Leclerc , Mikhail Pachkov , Lisa Morisseau , Fumiya Tokito , Cecile Legallais et al.

Molecular Omics, 2024, ⟨10.1039/D4MO00082J⟩

Article dans une revue hal-04787625v1
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Transcriptomic profiling analysis of the effect of palmitic acid on 3D spheroids of β-like cells derived from induced pluripotent stem cells

Lisa Morisseau , Fumiya Tokito , Mathilde Lucas , Stéphane Poulain , Soo Hyeon Kim et al.

Gene, 2024, 917, pp.148441. ⟨10.1016/j.gene.2024.148441⟩

Article dans une revue hal-04608624v1
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Investigation of the metabolomic crosstalk between liver sinusoidal endothelial cells and hepatocytes exposed to paracetamol using organ-on-chip technology

Taha Messelmani , Anne Le Goff , Fabrice Soncin , Françoise Gilard , Zied Souguir et al.

Toxicology, 2023, 492, pp.153550. ⟨10.1016/j.tox.2023.153550⟩

Article dans une revue hal-04212804v1
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Generation of β-like cell subtypes from differentiated human induced pluripotent stem cells in 3D spheroids

Lisa Morisseau , Fumiya Tokito , Stéphane Poulain , Valérie Plaisance , Valerie Pawlowski et al.

Molecular Omics, 2023, 19 (10), pp.810-822. ⟨10.1039/D3MO00050H⟩

Article dans une revue hal-04209565v1
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Microencapsulated Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells: Optimizing 3D Culture for Tissue Engineering Applications

Marwa Hussein , Mattia Pasqua , Ulysse Pereira , Nassima Benzoubir , Jean-Charles Duclos-Vallée et al.

Cells, 2023, 12 (6), pp.865. ⟨10.3390/cells12060865⟩

Article dans une revue hal-04193769v1
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Flow rate variations in microfluidic circuits with free surfaces

Taha Messelmani , Isabela Zarpellon Nascimento , Eric Leclerc , Cécile Legallais , Adam Meziane et al.

Microfluidics and Nanofluidics, 2023, 27 (12), pp.79. ⟨10.1007/s10404-023-02691-y⟩

Article dans une revue hal-04257314v1
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Groupe Néphrologie verte de la SFNDT : premières réflexions

Charles Chazot , Hafsah Hachad , Pierre Filipozzi , Cécile Legallais , Perrine Jullien et al.

Néphrologie & Thérapeutique, 2023, 19 (1), pp.23-33. ⟨10.1684/ndt.2023.1⟩

Article dans une revue (article de synthèse) hal-04294264v1
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Coculture model of a liver sinusoidal endothelial cell barrier and HepG2/C3a spheroids-on-chip in an advanced fluidic platform

Taha Messelmani , Anne Le Goff , Fabrice Soncin , Zied Souguir , Franck Merlier et al.

Journal of Bioscience and Bioengineering, 2023, ⟨10.1016/j.jbiosc.2023.10.006⟩

Article dans une revue hal-04288584v1
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Evidence of Adult Features and Functions of Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells and Self-Organized as Organoids

Antonietta Messina , Eléanor Luce , Nassima Benzoubir , Mattia Pasqua , Ulysse Pereira et al.

Cells, 2022, 11 (3), ⟨10.3390/cells11030537⟩

Article dans une revue hal-03561619v1
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Analysis of the transcriptome and metabolome of pancreatic spheroids derived from human induced pluripotent stem cells and matured in an organ-on-a-chip

Amal Essaouiba , Rachid Jellali , Stéphane Poulain , Fumiya Tokito , Françoise Gilard et al.

Molecular Omics, 2022, 18 (8), pp.791-804. ⟨10.1039/d2mo00132b⟩

Article dans une revue hal-03861419v1
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Liver organ-on-chip models for toxicity studies and risk assessment

Taha Messelmani , Lisa Morisseau , Yasuyuki Sakai , Cécile Legallais , Anne Le Goff et al.

Lab on a Chip, 2022, 22 (13), pp.2423-2450. ⟨10.1039/d2lc00307d⟩

Article dans une revue hal-03861401v1
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Electrodialysis Can Lower the Environmental Impact of Hemodialysis

Ahmed Abarkan , Nabil Grimi , Hubert Métayer , Tarik Sqalli Houssaïni , C. Legallais

Membranes, 2022, 12 (1), pp.45. ⟨10.3390/membranes12010045⟩

Article dans une revue hal-03590375v1
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Investigation of the Exometabolomic Profiles of Rat Islets of Langerhans Cultured in Microfluidic Biochip

Amal Essaouiba , Rachid Jellali , Françoise Gilard , Bertrand Gakière , Teru Okitsu et al.

Metabolites, 2022, 12 (12), pp.1270. ⟨10.3390/metabo12121270⟩

Article dans une revue hal-04213642v1
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Development of Liver-on-Chip Integrating a Hydroscaffold Mimicking the Liver’s Extracellular Matrix

Taha Messelmani , Anne Le Goff , Zied Souguir , Victoria Maes , Méryl Roudaut et al.

Bioengineering, 2022, 9, ⟨10.3390/bioengineering9090443⟩

Article dans une revue hal-03861410v1
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Multiscale-Engineered Muscle Constructs: PEG Hydrogel Micro-Patterning on an Electrospun PCL Mat Functionalized with Gold Nanoparticles

Megane Beldjilali-Labro , Rachid Jellali , Alexander David Brown , Alejandro Garcia Garcia , Augustin Lerebours et al.

International Journal of Molecular Sciences, 2022, 23 (1), pp.260. ⟨10.3390/ijms23010260⟩

Article dans une revue hal-03590377v1
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Validation of HepG2/C3A Cell Cultures in Cyclic Olefin Copolymer Based Microfluidic Bioreactors

Leire Etxeberria , Taha Messelmani , Jon Haitz Badiola , Andreu Llobera , Luis Fernandez et al.

Polymers, 2022, 14 (21), pp.4478. ⟨10.3390/polym14214478⟩

Article dans une revue hal-03861408v1
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Preclinical characterization of alginate‐Poly‐L‐Lysine encapsulated HepaRG for extracorporeal liver supply

Mattia Pasqua , Ulysse Pereira , Claire de Lartigue , Jonathan Nicolas , Pascale Vigneron et al.

Biotechnology and Bioengineering, 2021, 118 (1), ⟨10.1002/bit.27583⟩

Article dans une revue hal-02961888v1
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Analysis of the behavior of 2D monolayers and 3D spheroid human pancreatic beta cells derived from induced pluripotent stem cells in a microfluidic environment

Amal Essaouiba , Rachid Jellali , Marie Shinohara , Benedikt Scheidecker , Cécile Legallais et al.

Journal of Biotechnology, 2021, 330, pp.45-56. ⟨10.1016/j.jbiotec.2021.02.009⟩

Article dans une revue hal-03285819v1
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Cryogel-Integrated Biochip for Liver Tissue Engineering

Lilandra Boulais , Rachid Jellali , Ulysse Pereira , Eric Leclerc , Sidi A Bencherif et al.

ACS Applied Bio Materials, 2021, 4 (7), pp.5617-5626. ⟨10.1021/acsabm.1c00425⟩

Article dans une revue hal-03322953v1
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Donor variability alters differentiation and mechanical cohesion of tissue-engineered constructs with human endothelial/MSC co-culture

Timothée Baudequin , Marie Naudot , Sébastien Dupont , Sylvie Testelin , Bernard Devauchelle et al.

The International Journal of Artificial Organs, 2021, 44 (11), pp.868-879. ⟨10.1177/03913988211051758⟩

Article dans une revue hal-03433092v2
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Investigation of steatosis profiles induced by pesticides using liver organ-on-chip model and omics analysis

Rachid Jellali , Sebastien Jacques , Amal Essaouiba , Françoise Gilard , Franck Letourneur et al.

Food and Chemical Toxicology, 2021, 152, ⟨10.1016/j.fct.2021.112155⟩

Article dans une revue hal-03285733v1
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Monitoring mechanical stimulation for optimal tendon tissue engineering: a mechanical and biological multiscale study

Alejandro Garcia Garcia , Jean-Baptiste Perot , Megane Beldjilali-Labro , Quentin Dermigny , Marie Naudot et al.

Journal of Biomedical Materials Research Part A, 2021, ⟨10.1002/jbm.a.37180⟩

Article dans une revue hal-03029652v1
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Development of a pancreas-liver organ-on-chip coculture model for organ-to-organ interaction studies

Amal Essaouiba , Teru Okitsu , R. Kinoshita , Rachid Jellali , Yasuyuki Sakai et al.

Biochemical Engineering Journal, 2020, 164, pp.107783. ⟨10.1016/j.bej.2020.107783⟩

Article dans une revue hal-03095499v1
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Electrospinning of biomedically relevant gradient scaffolds: From honeycomb to randomly-oriented microstructure

Christopher Leon-Valdivieso , Alejandro Garcia-Garcia , Cécile Legallais , Fahmi Bedoui

Polymer, 2020, 202, pp.122606. ⟨10.1016/j.polymer.2020.122606⟩

Article dans une revue hal-02884169v1
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Microwell-based pancreas-on-chip model enhances genes expression and functionality of rat islets of Langerhans

Amal Essaouiba , Teru Okitsu , Rachid Jellali , Marie Shinohara , Mathieu Danoy et al.

Molecular and Cellular Endocrinology, 2020, 112, pp.110892. ⟨10.1016/j.mce.2020.110892⟩

Article dans une revue hal-02884096v1
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The combination of a poly‐caprolactone/nano‐hydroxyapatite honeycomb scaffold and mesenchymal stem cells promotes bone regeneration in rat calvarial defects

Marie Naudot , Alejandro Garcia Garcia , Nicolas Jankovsky , Anaïs Barre , Luciane Zabijak et al.

Journal of Tissue Engineering and Regenerative Medicine, 2020, 65, pp.20-31. ⟨10.1002/term.3114⟩

Article dans une revue hal-02961861v1
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Cold-to-warm machine perfusion of the liver: a novel circuit for an uninterrupted combined perfusion protocol

Claire Goumard , Eric Savier , Jerome Danion , Jérôme Pelissie , Cécile Legallais et al.

HPB, 2020, 22 (6), pp.927-933. ⟨10.1016/j.hpb.2020.04.001⟩

Article dans une revue hal-02884180v1
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HepaRG Self-Assembled Spheroids in Alginate Beads Meet the Clinical Needs for Bioartificial Liver

Mattia Pasqua , Ulysse Pereira , Antonietta Messina , Claire de Lartigue , Pascale Vigneron et al.

Tissue Engineering: Parts A, B, and C, 2020, 26 (11-12), pp.613-622. ⟨10.1089/ten.tea.2019.0262⟩

Article dans une revue hal-02884175v1
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In Vitro Bone Cell Response to Tensile Mechanical Solicitations: Is There an Optimal Protocol?

Timothée Baudequin , Cécile Legallais , Fahmi Bedoui

Biotechnology Journal, 2019, 14 (1), pp.1800358. ⟨10.1002/biot.201800358⟩

Article dans une revue hal-02061207v1
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Nanotechnology and Bioartificial Liver Engineering. Two Rival Paths for “Converging Technology”

Xavier Guchet , Cécile Legallais

Philosophia Scientiae, 2019, 23-1, pp.121-135. ⟨10.4000/philosophiascientiae.1839⟩

Article dans une revue hal-02140040v1
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Bioartificial liver: biomechanical considerations

L. Boulais , M. Pasqua , C. de Lartigue , R. Jellali , U. Pereira et al.

Computer Methods in Biomechanics and Biomedical Engineering, 2019, 44th Congress of the Société de Biomécanique, 22 (sup1), pp.S370-S372. ⟨10.1080/10255842.2020.1714948⟩

Article dans une revue hal-03322978v1
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Biomaterials in Tendon and Skeletal Muscle Tissue Engineering: Current Trends and Challenges

Megane Beldjilali-Labro , Alejandro Garcia Garcia , Firas Farhat , Fahmi Bedoui , Jean-François Grosset et al.

Materials, 2018, 11 (7), pp.1116. ⟨10.3390/ma11071116⟩

Article dans une revue hal-01956820v1
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Poly(ε-caprolactone)/Hydroxyapatite 3D Honeycomb Scaffolds for a Cellular Microenvironment Adapted to Maxillofacial Bone Reconstruction

Alejandro Garcia Garcia , Anne Hebraud , Jean-Luc Duval , Corinne Wittmer , Ludovic Gaut et al.

ACS Biomaterials Science and Engineering, 2018, 4 (9), pp.3317-3326. ⟨10.1021/acsbiomaterials.8b00521⟩

Article dans une revue hal-02393845v1

Metabolomics-on-a-chip approach to study hepatotoxicity of DDT, permethrin and their mixtures

Rachid Jellali , Françoise Gilard , Vittoria Pandolfi , Audrey Legendre , Marie-José Fleury et al.

Journal of Applied Toxicology, 2018, 38 (8), pp.1121-1134. ⟨10.1002/jat.3624⟩

Article dans une revue hal-02357461v1
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Bioengineering Organs for Blood Detoxification

Cécile Legallais , Dooli Kim , Sylvia Mihaila , Milos Mihajlovic , Marina Figliuzzi et al.

Advanced Healthcare Materials, 2018, 7 (21), pp.1800430. ⟨10.1002/adhm.201800430⟩

Article dans une revue hal-01956818v1

Mass Transfers in a Fluidized Bed Bioreactor using Alginate Beads for a Future Bioartificial Liver

B. David , E. Dore , M.Y. Jaffrin , C. Legallais

The International Journal of Artificial Organs, 2018, 27 (4), pp.284-293. ⟨10.1177/039139880402700404⟩

Article dans une revue hal-02149863v1
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The Osteogenic and Tenogenic Differentiation Potential of C3H10T1/2 (Mesenchymal Stem Cell Model) Cultured on PCL/PLA Electrospun Scaffolds in the Absence of Specific Differentiation Medium

Timothée Baudequin , Ludovic Gaut , Marc Mueller , Angela Huepkes , Birgit Glasmacher et al.

Materials, 2017, 10 (12), pp.1387. ⟨10.3390/ma10121387⟩

Article dans une revue hal-02938374v1
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Alginate-Based Cell Microencapsulation for Tissue Engineering and Regenerative Medicine

Vittoria Pandolfi , Ulysse Pereira , Murielle Dufresne , Cécile Legallais

Current Pharmaceutical Design, 2017, 23 (26), ⟨10.2174/1381612823666170609084016⟩

Article dans une revue hal-02938367v1
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A new prescription model for regional citrate anticoagulation in therapeutic plasma exchanges

Sébastien Kissling , Cécile Legallais , Menno Pruijm , Daniel Teta , Bruno Vogt et al.

BMC Nephrology, 2017, 18 (1), pp.81. ⟨10.1186/s12882-017-0494-9⟩

Article dans une revue hal-02938371v1

Optimizing the fluidized bed bioreactor as an external bioartificial liver

Sarah Figaro , Ulysse Pereira , Hiram Rada , Nicolas Semenzato , Dominique Pouchoulin et al.

The International Journal of Artificial Organs, 2017, 40 (4), pp.196-203. ⟨10.5301/ijao.5000567⟩

Article dans une revue hal-02938255v1

Expansion properties of alginate beads as cell carrier in the fluidized bed bioartificial liver

Seyed Danial Naghib , Vittoria Pandolfi , Ulysse Pereira , Rossella Girimonte , Efrem Curcio et al.

Powder Technology, 2017, 316, pp.711-717. ⟨10.1016/j.powtec.2016.12.047⟩

Article dans une revue hal-02938369v1
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Towards the Development and Characterization of an Easy Handling Sheet-Like Biohybrid Bone Substitute

Timothée Baudequin , Fahmi Bedoui , Murielle Dufresne , Patrick Paullier , Cécile Legallais

Tissue Engineering: Parts A, B, and C, 2015, 21 (11-12), pp.1895-1905. ⟨10.1089/ten.tea.2014.0580⟩

Article dans une revue hal-03433119v1

SUPPLIVER: Bioartificial supply for liver failure

S. Figaro , Ulysse Pereira , A-S. Dumé , H. Rada , S. Capone et al.

Innovation and Research in BioMedical engineering, 2015, 36 (2), pp.101-109. ⟨10.1016/j.irbm.2015.01.010⟩

Article dans une revue hal-03411627v1

Numerical simulation of the fluid structure interactions in a compliant patient-specific arteriovenous fistula

Iolanda Decorato , Zaher Kharboutly , Tommaso Vassallo , Justin Penrose , Cécile Legallais et al.

International Journal for Numerical Methods in Biomedical Engineering, 2014, 30 (2), pp.143-159. ⟨10.1002/cnm.2595⟩

Article dans une revue istex hal-02019727v1

Comparison of two Endovascular Treatments of a Stenosed Arteriovenous Fistula: Balloon-Angioplasty with and without Stenting

Iolanda Decorato , Zaher Kharboutly , Cécile Legallais , Anne-Virginie Salsac

The International Journal of Artificial Organs, 2014, 37 (10), pp.763-772. ⟨10.5301/ijao.5000324⟩

Article dans une revue hal-02019770v1

Influence of an Arterial Stenosis on the Hemodynamics Within an Arteriovenous Fistula (AVF): Comparison Before and After Balloon-Angioplasty

Iolanda Decorato , Anne-Virginie Salsac , Cécile Legallais , Mona Alimohammadi , Vanessa Diaz-Zuccarini et al.

Cardiovascular Engineering and Technology, 2014, 5 (3), pp.233-243. ⟨10.1007/s13239-014-0185-7⟩

Article dans une revue hal-02019623v1

Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips

Régis Baudoin , Jean-Matthieu Prot , Grégory Nicolas , Jessy Brocheton , Céline Brochot et al.

Xenobiotica, 2013, 43 (2), pp.140-152. ⟨10.3109/00498254.2012.706725⟩

Article dans une revue ineris-00963431v1

An appropriate selection of 3D alginate culture model for hepatic Huh-7 cell line encapsulation intended for viral studies

N.M. Tran , M. Dufresne , Gilles Duverlie , Sandrine Castelain , Christian Défarge et al.

Tissue Engineering: Parts A, B, and C, 2013, 19 (1-2), pp.103-113. ⟨10.1089/ten.tea.2012.0139⟩

Article dans une revue insu-00723045v1
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Human hepatic cell behavior on polysulfone membrane with double porosity level

Murielle Dufresne , Patrice Bacchin , Giulia Cerino , Jean-Christophe Remigy , Gerard Nathanael Adrianus et al.

Journal of Membrane Science, 2013, vol. 428, pp. 454-461. ⟨10.1016/j.memsci.2012.10.041⟩

Article dans une revue hal-00788387v1

Investigation of ifosfamide nephrotoxicity induced in a liver-kidney co-culture biochip.

Leila Choucha-Snouber , Caroline Aninat , Laurent Grsicom , Geoffrey Madalinski , Céline Brochot et al.

Biotechnology and Bioengineering, 2013, 110 (2), pp.597-608. ⟨10.1002/bit.24707⟩

Article dans une revue istex inserm-00864839v1
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Impact of Alginate Composition: From Bead Mechanical Properties to Encapsulated HepG2/C3A Cell Activities for In Vivo Implantation

Stephanie Capone , Murielle Dufresne , Mathias Rechel , Marie-José Fleury , Anne-Virginie Salsac et al.

PLoS ONE, 2013, 8 (4), pp.e62032. ⟨10.1371/journal.pone.0062032⟩

Article dans une revue hal-02019744v1

Metabolomics-on-a-chip of hepatotoxicity induced by anticancer drug flutamide and its active metabolite hydroxyflutamide using HepG2/C3a microfluidic biochips

Leila Choucha-Snouber , Andrei Bunescu , Cécile Legallais , Céline Brochot , Marc-Emmanuel Dumas et al.

Toxicological Sciences, 2013, 132 (1), pp.8-20. ⟨10.1093/toxsci/kfs230⟩

Article dans une revue ineris-00963445v1

Metabolomics-on-a-Chip and Predictive Systems Toxicology in Microfluidic Bioartificial Organs

Laetitia Shintu , Régis Baudoin , Vincent Navratil , Jean-Matthieu Prot , Clément Pontoizeau et al.

Analytical Chemistry, 2012, 84 (4), pp.1840-1848. ⟨10.1021/ac2011075⟩

Article dans une revue hal-00699575v1
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Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: Application to acetaminophen injury

Jean-Matthieu Prot , Andrei Bunescu , Bénédicte Elena-Herrmann , Caroline Aninat , Leila Choucha Snouber et al.

Toxicology and Applied Pharmacology, 2012, 259 (3), pp.270-280. ⟨10.1016/j.taap.2011.12.017⟩

Article dans une revue hal-00699551v1

Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip

J.M. Prot , A.S. Briffaut , F. Letourneur , P. Chafey , F. Merlier et al.

PLoS ONE, 2011, 6 (8), pp.e21268. ⟨10.1371/journal.pone.0021268⟩

Article dans une revue hal-00637409v1

ENDOCOM: Implantable wireless pressure sensor for the follow-up of abdominal aortic aneurysm stented

Olivier Romain , Johan Mazeyrat , Patrick Garda , Hakeim Talleb , David Lautru et al.

Innovation and Research in BioMedical engineering, 2011, 32 (3), pp.163 - 168. ⟨10.1016/j.irbm.2011.01.017⟩

Article dans une revue istex hal-00665334v1

Improvement of HepG2/C3a cell functions in a microfluidic biochip.

Jean Matthieu Prot , Caroline Aninat , Laurent Griscom , Florence Razan , Céline Brochot et al.

Biotechnology and Bioengineering, 2011, 108 (7), pp.1704-15. ⟨10.1002/bit.23104⟩

Article dans une revue istex hal-00740224v1

A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening

Jean-Matthieu Prot , Orianne Videau , Céline Brochot , Cécile Legallais , Henri Benech et al.

International Journal of Pharmaceutics, 2011, 108 (1-2), pp.67-75. ⟨10.1016/j.ijpharm.2011.01.054⟩

Article dans une revue istex ineris-00963290v1

Numerical and experimental study of blood flow through a patient-specific arteriovenous fistula used for hemodialysis

Zaher Kharboutly , Valérie Deplano , Eric Bertrand , Cécile Legallais

Medical Engineering & Physics, 2010, 32, pp.111-118. ⟨10.1016/j.medengphy.2009.10.013⟩

Article dans une revue istex hal-00429960v1

Analysis of the mass transfers in an artificial kidney microchip

A. Ould-Dris , P. Paullier , Laurent Griscom , Cécile Legallais , E. Leclerc

Journal of Membrane Science, 2010, 352, pp.116-125. ⟨10.1016/j.memsci.2010.02.007⟩

Article dans une revue istex hal-00592403v1

Prédiction de la toxicocinétique in vivo de substances chimiques à partir de données in vitro et de modèles QSAR

Dany Habka , Alexandre R.R. Pery , Cécile Legallais , Céline Brochot

Environnement, Risques & Santé, 2010, 9 (6), pp.489-501. ⟨10.1684/ers.2010.0396⟩

Article dans une revue ineris-00963259v1

Alginate-encapsulated HepG2 Cells in a Fluidized Bed Bioreactor Maintain Function in Human Liver Failure Plasma

Sam Coward , Cécile Legallais , Bertrand David , Michael Thomas , Ying Foo et al.

Artificial Organs, 2009, 33 (12), pp.1117-1126. ⟨10.1111/j.1525-1594.2009.00821.x⟩

Article dans une revue istex hal-02149842v1

Les dispositifs de suppléance hépatique

A. Gautier , C. Legallais

Réanimation, 2009, 18 (5), pp.413-419. ⟨10.1016/j.reaurg.2009.05.010⟩

Article dans une revue hal-00437800v1

In vitro tests and modelization of bicarbonate kinetics and mass transfers during online hemodiafiltration

H. Morel , M.Y. Jaffrin , P. Paullier , C. Legallais

The International Journal of Artificial Organs, 2009, 32, pp.482-491. ⟨10.1177/039139880903200802⟩

Article dans une revue hal-00437233v1

Artificial and bioartificial liver devices: present and future

B. Carpentier , A. Gautier , C. Legallais

Gut, 2009, 58 (12), pp.1690-1702. ⟨10.1136/gut.2008.175380⟩

Article dans une revue istex hal-00437697v1

Hollow fiber bioartificial liver: Physical and biological characterization with C3A cells

A. Gautier , A. Ould-Dris , M. Dufresne , P. Paullier , B. von Harten et al.

Journal of Membrane Science, 2009, 341 ((1-2)), pp.203-213. ⟨10.1016/j.memsci.2009.06.007⟩

Article dans une revue istex hal-00437709v1

The place of adsorption and biochromatography in extracorporeal liver support systems

C. Legallais , A. Gautier , M. Dufresne , B. Carpentier , R. Baudoin

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2008, 961 (2), pp.171-176. ⟨10.1016/j.jchromb.2007.07.048⟩

Article dans une revue istex hal-00339871v1

Three-dimensional growth of human hepatoma C3A cells within alginate beads for fluidized bioartificial liver

A. Kinasiewicz , A. Gautier , D. Lewińska , A. Śmietanka , C. Legallais et al.

The International Journal of Artificial Organs, 2008, 31 (4), pp.340- 347. ⟨10.1177/039139880803100411⟩

Article dans une revue hal-00339867v1

Solid–liquid mass transfers in an airlift reactor incorporating alginate beads for the application as a bioartificial liver

S. Demming , A. Gautier , C. Legallais , A. Ould-Dris

Chemical Engineering and Processing: Process Intensification, 2008, 47 (12), pp.2370-2378. ⟨10.1016/j.cep.2008.01.013⟩

Article dans une revue istex hal-00336365v1

Générateurs d'hémodialyse : état du marché français

S. Merlo , A. Donadey , B. Coevoet , C. Legallais

ITBM RBM, 2007, 28, pp.150-168. ⟨10.1016/j.rbmret.2007.07.004⟩

Article dans une revue hal-00282676v1

Development of a renal microchip for in vitro distal tubule models

R. Baudoin , L. Griscom , M. Monge , C. Legallais , E. Leclerc

Biotechnology Progress, 2007, 23, pp.1245-1253. ⟨10.1021/bp0603513⟩

Article dans une revue istex hal-00196149v1

Investigations into the relationship between hemodynamics and vascular alterations in an established arteriovenous fistula

Z. Kharboutly , M. Fenech , J.M. Treutenaere , I. Claude , C. Legallais

Medical Engineering & Physics, 2007, 29 (9), pp.999-1007. ⟨10.1016/j.medengphy.2006.10.018⟩

Article dans une revue istex hal-03842143v1

Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity

R. Baudoin , Anne Corlu , L. Griscom , C. Legallais , E. Leclerc

Toxicology in Vitro, 2007, 21, pp.535-544. ⟨10.1016/j.tiv.2006.11.004⟩

Article dans une revue istex hal-00172268v1

Selective control of liver and kidney cells migration during organotypic cocultures inside fibronectin-coated rectangular silicone microchannels

Eric Leclerc , Régis Baudoin , Anne Corlu , Laurent Griscom , Jean Luc Duval et al.

Biomaterials, 2007, 28 (10), pp.1820-1829. ⟨10.1016/j.biomaterials.2006.11.044⟩

Article dans une revue istex hal-00172298v1

Culture of C3A Cells in Alginate Beads for Fluidized Bed Bioartificial Liver.

A. Kinasiewicz , A. Gautier , D. Lewinska , J. Bukowski , C. Legallais et al.

Transplantation Proceedings, 2007, 39 (9), pp.2911-2913. ⟨10.1016/j.transproceed.2007.08.062⟩

Article dans une revue istex hal-00282673v1

A theoretical study of oxygen transfer including cell necrosis for the design of a bioartificial pancreas

J.L. Dulong , C. Legallais

Biotechnology and Bioengineering, 2007, 96, pp.990-998. ⟨10.1002/bit.21140⟩

Article dans une revue istex hal-00282668v1

Mechanical properties of alginate beads hosting hepatocytes in a fluidized bed bioreactor.

C David , L. Barbe , D. Barthès-Biesel , C. Legallais

The International Journal of Artificial Organs, 2006, 29 (8), pp.756-63. ⟨10.1177/039139880602900805⟩

Article dans une revue hal-02149847v1

Study of Osteoblastic Cells in a Microfluidic Environment

E. Leclerc , B. David , L Griscom , Bruno Le Pioufle , T. Fujii et al.

Biomaterials, 2006, 27 (4), pp.558-595. ⟨10.1016/j.biomaterials.2005.06.002⟩

Article dans une revue istex hal-00778216v1

Perfusion culture of mammalian cells in microfluidic environments for tissue engineering applications

Eric Leclerc , Bertrand David , Laurent Griscom , Bruno Lepioufle , Yasuyuki Sakai et al.

La Houille Blanche - Revue internationale de l'eau, 2006, 3 (3), pp.56-59. ⟨10.1051/lhb:200603008⟩

Article dans une revue istex hal-02149903v1

Guidance of liver and kidney organotypic cultures inside rectangular silicone microchannels.

E. Leclerc , A. Corlu , L. Griscom , R. Baudoin , C. Legallais

Biomaterials, 2006, 27, pp.4109-4119. ⟨10.1016/j.biomaterials.2006.03.031⟩

Article dans une revue istex hal-00090178v1

What are the relevant parameters for the geometrical optimization of an implantable bioartificial pancreas ?

J.L. Dulong , C. Legallais

Journal of Biomechanical Engineering, 2005, 127 (7), pp.1054-1061. ⟨10.1115/1.2073407⟩

Article dans une revue hal-00017278v1

In vitro assessment of encapsulated C3A hepatocytes functions in a fluidized bed bioreactor

B. David , M. M. Dufresne , M. Nagel , C. Legallais

Biotechnology Progress, 2004, 20 (4), pp.1204-1212. ⟨10.1021/bp034301z⟩

Article dans une revue istex hal-02149856v1

Bioartificial livers (BAL): current technological aspects and future developments

C. Legallais , B David , E. Dore

Journal of Membrane Science, 2001, 181 (1), pp.81-95. ⟨10.1016/S0376-7388(00)00539-1⟩

Article dans une revue istex hal-02149872v1
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Triphasic electrospun scaffold with dynamic cells coculture for tissue engineering of bone-tendon-muscle junctions

Nicolas Rivoallan , Morgane Lagier , Timothée Baudequin , Marc Mueller , Pascale Vigneron et al.

ESAO-IFAO Congress, ESAO-IFAO, Sep 2024, Aachen (Aix la Chapelle), Germany. pp.421-565, ⟨10.1177/03913988241279540⟩

Communication dans un congrès hal-04754056v1

Investigation of Oleic Acid, Palmitic Acid and their mixture on the development of hepatic steatosis using liver-on-chip technology

Lisa Morisseau , C. Legallais , Amar Abderrahmani , Yasuyoshi Sakai , Eric Leclerc et al.

49th ESAO Congress, Aug 2023, Bergamo, Italy

Communication dans un congrès hal-04476949v1

Advancements towards artificial organs

C. Legallais

ESOT Congres, European Society for Orthotopic Transplantation, Sep 2023, Athènes, Greece

Communication dans un congrès hal-04583786v1

Philosophy of science, a tool to face engineered liver challenges

M Guillet , U Pereira , C de Lartigue , C Legallais , X Guchet

Termis –EU 2022, Jun 2022, Krakow, Poland

Communication dans un congrès hal-04471738v1
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Contrôle découlement et suivi de prolifération dans des biopuces hépatiques

Taha Messelmani , Adam Meziane , William César , Marine Verhulsel , Zied Souguir et al.

25`eme Congrès Français de Mécanique, Aug 2022, Nantes, France

Communication dans un congrès hal-04497647v1

Membranes and Porous Scaffolds for Bioartificial Organs

C. Legallais

EuroMembrane 2022, Nov 2022, Sorrento (Italie), Italy

Communication dans un congrès hal-04475702v1

Evaluation of treatment strategies for acute liver failure based on a perfused bed bioreactor

C de Lartigue , U Pereira , M Guillet , C Legallais

9th World Congress of Biomechanics, Jul 2022, Tai pei, Taiwan

Communication dans un congrès hal-04471743v1

Development of liver-on-chip model integrating LSEC barrier and hepatocytes organoids for toxicity application

Taha Messelmani , Anne Le Goff , Fabrice Soncin , Zied Souguir , Elodie Vandenhaute et al.

The 1st edition of the MicroPhysio conference on "Micro-physiological models: From organoids to organs-on-chip", Apr 2022, Cargese (Corse), France

Communication dans un congrès hal-04497703v1

Modulating mechanical and biological parameters to investigate phenotypic changes in human liver sinusoidal endothelial cells

A Couderc , K El Kirat , P Moret , C Legallais , A Le Goff et al.

2021 TERMIS 6th World Congress, Nov 2021, Maastricht, Netherlands

Communication dans un congrès hal-04476517v1

Development of an advanced liver organ-on-chip integrating hydroscaffold mimicking cell matrix

Taha Messelmani , Zied Souguir , Victoria Maes , Anne Le Goff , Elodie Vandenhaute et al.

47th ESAO Congress, Sep 2021, London (U.K.), United Kingdom

Communication dans un congrès hal-04497725v1

Can a new perfused dynamic bioreactor hosting heparg in alginate-poly-l-lysine beads meet the clinical needs for extracorporeal liver supply?

C de Lartigue , U Pereira , M Pasqua , J Nicolas , J Rialland et al.

47th ESAO congress, Sep 2021, London, United Kingdom

Communication dans un congrès hal-04471728v1

3D liver-on-chip model integrating hydrogel mimicking cell matrix

Taha Messelmani , Zied Souguir , Victoria Maes , Anne Le Goff , Eric Leclerc et al.

TERMIS 6th World Congress, Nov 2021, Maastricht (Netherland), Netherlands

Communication dans un congrès hal-04500618v1

Ethical and epistemological questions in (bio)artificial organs

C. Legallais , X. Guchet

Joint IFAO-JSAO Congress, Japanese Society for Artificial Organs, Nov 2019, Osaka (JP), Japan

Communication dans un congrès hal-04583808v1

Cryogel integrated microchip : towards a human 3D model of liver cancer

Lilandra Boulais , Rachid Jellali , Ulysse Pereira , Patrick Paullier , Eric Leclerc et al.

Cancer Cells-on-Chip 2, Mar 2019, Lyon, France

Communication dans un congrès hal-04475771v1

The benefits of multiscale approaches in Liver Tissue Engineering

C. Legallais

46th Congress European Society for Artificial Organs, ESAO, Sep 2019, Hannover - Germany, Germany

Communication dans un congrès hal-04475719v1

Investigation of the Behavior of Rat Pancreatic Islets in an Organ-On-Chip Model

Amal Essaouiba , Teru Okitsu , Rachid Jellali , Marie Shinohara , Mathieu Danoy et al.

IFAO-JSAO Congress, Nov 2019, Osaka (JP), Japan

Communication dans un congrès hal-04475774v1

Bioartificial Liver: What's next ?

C. Legallais

ESOT Congress, European Society for Orthotopic Transplantation, Sep 2019, Copenhagen, Denmark

Communication dans un congrès hal-04583832v1

Liver on chip platform: key questions following 15 years of development

C. Legallais , Rachid Jellali , Eric Leclerc

International MicroNanoconference, Dec 2018, Amsterdam, Netherlands

Communication dans un congrès hal-04475722v1

Electrically Conductive Multi Dimensional Scaffolds With Controllable Architecture For Skeletal Muscle Engineering

Megane Beldjilali-Labro , Alejandro Garcia Garcia , Fahmi Bedoui , Rachid Jellali , Murielle Dufresne et al.

5th TERMIS World Congress, Aug 2018, Kyoto (Japan), Japan

Communication dans un congrès hal-04475764v1

Mechanical stimulation monitoring towards optimal tendon tissue reconstruction

Alejandro Garcia Garcia , Jean-Baptiste Perot , Marie Naudot , Sophie Le Ricousse , C. Legallais et al.

XLV ESAO Congress, Sep 2018, Madrid, Spain

Communication dans un congrès hal-04475768v1

Development and validation of a bioartificial liver device with fluidized bed bioreactors hosting alginate-encapsulated hepatocyte spheroids

S. Figaro , Ulysse Pereira , H. Rada , N. Semenzato , D. Pouchoulin et al.

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Aug 2015, Milan, France. pp.1335-1338, ⟨10.1109/embc.2015.7318615⟩

Communication dans un congrès hal-03411623v1

Liver-kidney microfluidic bioreactor for cell co-culture in drug studies

L. Choucha Snouber , Laurent Griscom , Pe Poleni , Florence Razan , Céline Brochot et al.

MICROTAS, Oct 2010, GRONINGEN, Netherlands. pp.0328

Communication dans un congrès hal-00756580v1

RFID implantable pressure sensor for the follow-up of abdominal aortic aneurysm stented

Olivier Romain , Johan Mazeyrat , Patrick Garda , Hakeim Talleb , David Lautru et al.

IEEE DTIS 2011 : 6th International conference on Design & Technology of Integrated Systems in nanoscale era, Apr 2011, Athens, Greece. pp.1-6, ⟨10.1109/DTIS.2011.5941418⟩

Communication dans un congrès hal-00600948v1
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Numerical study of the influence of wall compliance on the hemodynamics in a patient-specific arteriovenous fistula

Iolanda Decorato , Zaher Kharboutly , Cécile Legallais , Anne-Virginie Salsac

CFM 2011 - 20ème Congrès Français de Mécanique, Aug 2011, Besançon, France

Communication dans un congrès hal-03421275v1

Toxicologie predictive: les voies du futur

Ph Detilleux , L Vallier , C Legallais , E Leclerc , M Prot J et al.

Congrès de la SPTC - Société de Pharmaco-Toxicologie Cellulaire, May 2010, Paris, France

Communication dans un congrès hal-01122677v1

Calibration of PBPK models based on in vivo and in vitro data to describe complex biotransformation processes

Dany Habka , Alexandre R.R. Pery , C. Aninat , A. Corlu , C. Guguen-Guillouzo et al.

12. International Congress of Toxicology (IUTOX 2010), Jul 2010, Barcelone, Spain

Communication dans un congrès ineris-00970650v1

Comparison of the growth kinetics of hepatocarcinoma cells in a microfluidic bioreactor and Petri dishes

J.M. Prot , R. Baudoin , L. Griscom , C. Legallais , E. Leclerc

MMB 2009, Apr 2009, Québec, Canada

Communication dans un congrès hal-00457134v1

Microfluidic biochip for in vitro toxicity analysis

R. Baudoin , J.M. Prot , C. Legallais , E. Leclerc

ESAO 2009, Sep 2009, Compiègne, France

Communication dans un congrès hal-00456973v1

Use of a liver biochip as a tool in toxicological study.

J.M. Prot , R. Baudoin , L. Griscom , C. Legallais , E. Leclerc

XXXVI Annual meeting European Society for Artificial Organs. ESAO 2009, Sep 2009, Compiègne, France

Communication dans un congrès hal-00457136v1

Flow and mass transfer modeling for tissue engineering applications.

B. Carpentier , A. Gautier , P. Paullier , A. Ould-Dris , P. Layrolle et al.

33ème Congrès de la Société de Biomécanique, Sep 2008, Compiègne, France. pp.53-55

Communication dans un congrès hal-00345817v1

Bicarbonate and urea kinetics modeling during hemodialysis and online postdilution hemodiafiltration.

H. Morel , M.Y. Jaffrin , J. Vienken , C. Legallais

ESAO 2008, XXXV Annual Meeting European Society for Artificial Organs, Sep 2008, Genève, Switzerland. pp.65

Communication dans un congrès hal-00345030v1

In vitro bicarbonate and urea kinetics during hemodialysis and online hemodiafiltration.

H. Morel , M.Y. Jaffrin , C. Legallais , J. Vienken

33ème Congrès de la Société de Biomécanique, Sep 2008, Compiègne, France. pp.167

Communication dans un congrès hal-00344995v1

Cell Micro-Encapsulation and Bioartificial Liver.

C. Legallais , A. Gautier , B. Carpentier , Q. Vu Dinh , M. Dufresne et al.

8th World Biomaterials Congress, May 2008, Amsterdam, Netherlands

Communication dans un congrès hal-00345819v1

Modélisations numérique et expérimentale des écoulements sanguins dans une fistule artério veineuse

Zaher Kharboutly , Cécile Legallais , Valérie Deplano , Eric Bertrand

8ème Colloque National en calcul des structures, May 2007, Giens, France

Communication dans un congrès hal-00455960v1

Modélisations numérique et expérimentale des écoulements sanguins dans une fistule artério-veineuse.

Z. Kharboutly , C. Legallais , V. Deplano , E. Bertrand

8ème Colloque National en Calcul des Structures, May 2007, Giens, France

Communication dans un congrès hal-00294647v1
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Modélisations numérique et expérimentale des écoulements sanguins dans une fistule artério-veineuse

Zaher Kharboutly , Cécile Legallais , Valérie Deplano , Eric Bertrand

8e Colloque national en calcul des structures, CSMA, May 2007, Giens, France

Communication dans un congrès hal-01507578v1

Three dimensional growth of hepatic cells in alginate beads. Studies of beads optimization for fluidized bed bioreactor.

A. Kinasiewicz , A. Gautier , D. Lewinska , M. Dufresne , A. Smietanka et al.

34th ESAO Congress, Sep 2007, Krems, Austria

Communication dans un congrès hal-00290051v1

An example of bioartificial organ : combination of hepatocytes microencapsulation and fluidized bed technology for extracorporeal liver support.

A. Gautier , M. Dufresne , B. Carpentier , P. Paullier , C. Legallais

International Congress on “Biochromatography and Nanobiotechnologies", Feb 2007, Vellore, India

Communication dans un congrès hal-00289993v1

Bioartificial liver based on hollow fiber membrane : physical and biological characterization at micro scale level.

A. Gautier , H.D. Lemke , B. von Harten , M. Dufresne , C. Legallais

34th ESAO Congress, Sep 2007, Krems, Austria

Communication dans un congrès hal-00290030v1

Development of a cellular biochip mimicking in vitro organs for chronic toxicity analysis.

R. Baudoin , L. Griscom , A. Corlu , P. Layrolle , C. Legallais et al.

Transducers'07, 14th International Conference on Solid-State Sensors, actuators and Microsystems, Jun 2007, Lyon, France

Communication dans un congrès hal-00289965v1
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Validation des procédures de maillage pour l'étude des écoulements sanguins dans une fistule artério-veineuse réelle

Zaher Kharboutly , J.M. Treutenaere , I. Claude , M. Fenech , C. Legallais

CFM 2007 - 18ème Congrès Français de Mécanique, Aug 2007, Grenoble, France

Communication dans un congrès hal-03360384v1

Caractérisation des écoulements dans une fistule artério veineuse. Comparaison numérique expérimentale.

Zaher Kharboutly , Cécile Legallais , Eric Bertrand , Valérie Deplano

Journées scientifiques du GDR2760 : Interactions fluide structure biologiques, May 2007, Marseille, France

Communication dans un congrès hal-00456057v1

Production of bone substitutes in bioreactors : Modeling and culture of bone marrow stem cells.

B. Carpentier , J. Sohier , P. Layrolle , C. Legallais

34th ESAO Congress, Sep 2007, Krems, Austria

Communication dans un congrès hal-00289975v1

Application of cells microencapsulation for bioartificial liver in fluidized bed bioreactor.

A. Gautier , B. Carpentier , M. Dufresne , P. Paullier , C. Legallais

14th International Workshop on Bioencapsulation, Oct 2006, Lausanne, Switzerland

Communication dans un congrès hal-00118146v1

Development of a renal microfluidic device for future in vitro kidney model reconstruction.

R. Baudoin , L. Griscom , C. Legallais , E. Leclerc

XXXIII ESAO Congress, Jun 2006, Umea, Sweden

Communication dans un congrès hal-00116598v1

Liver organotypic chick embryo cultures on silicone microchannels.

E. Leclerc , A. Corlu , L. Griscom , R. Baudoin , C. Legallais

ESB 20th European Conference on Biomaterials, Sep 2006, Nantes, France

Communication dans un congrès hal-00118400v1

Human liver cells in a pilot-scale fluidised-bed bioreactor maintain performance in human liver failure plasma making them suitable for a bioartificial liver.

S. Coward , C. Legallais , A. Gautier , P. Paullier , M. Thomas et al.

5th World Congress of Biomechanics, Jul 2006, Munich, Germany

Communication dans un congrès hal-00118127v1

PDMS microdevices as new supports for in vitro bioartificial organs.

R. Baudoin , L. Griscom , C. Legallais , E. Leclerc

XXXIII ESAO Congress, Jun 2006, Umea, Sweden

Communication dans un congrès hal-00116600v1

Mass transfer studies in a model of fluidized bed bioartificial liver.

B. Carpentier , A. Gautier , P. Paullier , C. Legallais

XXXIII ESAO Congress, Jun 2006, Umea, Sweden

Communication dans un congrès hal-00118114v1

Activity of cells within alginate beads produced for fluidized bed bioreactor (bioartificial liver).

A. Kinasiewicz , A. Gautier , D. Lewinska , M. Dufresne , P. Paullier et al.

XXIII ESAO Congress, Jun 2006, Umea, Sweden

Communication dans un congrès hal-00118286v1

Development of a microfluidic devices for in vitro liver model.

R. Baudoin , L. Griscom , A. Corlu , C. Legallais , E. Leclerc

5th World Congress of Biomechanics, Jul 2006, Munich, Germany

Communication dans un congrès hal-00116596v1

In vitro optimization of alginate bead production for hepatocytes encapsulation in the fluidized bed bioartificial liver.

A. Gautier , A. Kinasiewicz , B. Carpentier , D. Lewinska , P. Paullier et al.

5th World Congress of Biomechanics, Jul 2006, Munich, Germany

Communication dans un congrès hal-00118148v1

Numerical Simulation of Blood Flow in a side-to-end fistula for hemodialysis.

Z. Kharboutly , J.M. Treutenaere , M. Fenech , T. Chambon , I. Claude et al.

5th World Congress of Biomechanics, Jul 2006, Munich, Germany

Communication dans un congrès hal-00118280v1

Blood flow simulation in an arteriovenous fistula.

Z. Kharboutly , M. Fenech , J.M. Treutenaere , I. Claude , C. Legallais

XXth Congress International Society for Biomechanics, 2005, Cleveland, Ohio, United States

Communication dans un congrès hal-00019375v1

CFD modeling of unsteady blood flow in a arteriovenous fistula reconstructed from angioscanner.

Z. Kharboutly , M. Fenech , J.M. Treutenaere , I. Claude , C. Legallais

30ème Congrès de la Société de Biomécanique. In Computer Methods in Biomechanics and Biomedical Engineering, 8,, 2005, Bruxelles, Belgium. pp.161-162

Communication dans un congrès hal-00019374v1

Behaviour of osteoblast-like cells in cellular microdevices

E. Leclerc , B. David , R. Warocquier-Clerout , L. Griscom , Bruno Le Pioufle et al.

Micro Total Analysis Systems 2004, Vol 1, 2005, Netherlands. pp.396-398

Communication dans un congrès hal-00795188v1

Hydrodynamic behaviour of several types of fluidized bed bioreactor used in a bioartificial liver.

R. Baudoin , A. Gautier , S.M. Coward , B. David , H.J.F. Hodgson et al.

XXXII ESAO Congress, 2005, Bologne, Italy

Communication dans un congrès hal-00018719v1

Non woven electrospun scaffold with continuous gradient from honeycomb like to aligned structures for osteotendinous junction tissue engineering

Nicolas Rivoallan , Timothée Baudequin , Birgit Glasmacher , C. Legallais

49th ESAO congress, Aug 2023, Bergamo, Italy

Poster de conférence hal-04476951v1

What is a biologically inspired human-designed liver?[

M Guillet , U Pereira , C de Lartigue , C Legallais , X Guchet

6th World congress Termis 2021, Nov 2021, Maasticht, Netherlands

Poster de conférence hal-04471715v1

Evaluation of treatment strategies for acute liver failure based on a perfused bed bioreactor

C de Lartigue , U Pereira , M Pasqua , J Nicolas , J Rialland et al.

6th World congress Termis 2021, Nov 2021, Maasticht, Netherlands

Poster de conférence hal-04471720v1

Activity of encapsulated HepaRG in fluidized bed artificial liver

C de Lartigue , M Pasqua , U Pereira , C Legallais

Biomat – MatSan, Jun 2019, La grande Motte, France

Poster de conférence hal-04471634v1

Can HepaRG self-assembled spheroids fulfil the clinical needs for extracorporeal liver supply?

M Pasqua , U Pereira , A Messina , C de Lartigue , P Vigneron et al.

3D culture to organoids, Dec 2019, Paris, France

Poster de conférence hal-04471643v1

Can encapsulated HEPARG in alginate-polyl-lysine beads meet the clinical needs for extracorporeal liver supply?

M Pasqua , U Pereira , C de Lartigue , A Messina , P Vigneron et al.

3D culture to organoids, Dec 2019, Paris, France

Poster de conférence hal-04471711v1

Differentiation of human pluripotent stem cells into hepatocytes is more efficient in spheroids than in 2D culture

A Messina , U Pereira , C Legallais , A Dubart-Kupperschmitt

EASL the international liver congress, Oct 2018, Paris ( France), France

Poster de conférence hal-04471493v1

Cryogel-integrated hepatic cell culture microchips for liver tissue engineering

L Boulais , R Jellali , U Pereira , P Paullier , E Leclerc et al.

Termis world congres Kyoto, Sep 2018, Kyoto (Japan), Japan

Poster de conférence hal-04471609v1
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Microfluidic and Organ-on-a-chip-based Technologies for Diabetes Therapy and Research

Lisa Morisseau , Taha Messelmani , Amal Essaouiba , Yasuyuki Sakai , Anne Le Goff et al.

Nanotechnology for Diabetes Management, Royal Society of Chemistry, pp.188-232, 2022, Nanoscience & Nanotechnology Series, ⟨10.1039/9781839165498-00188⟩

Chapitre d'ouvrage hal-03895773v1
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Chapter 4 : Membrane bioreactors for bio-artificial pancreas

Rachid Jellali , Amal Essaouiba , Eric Leclerc , Cécile Legallais

Current Trends and Future Developments on (Bio-) Membranes, Elsevier, pp.77-108, 2020, ⟨10.1016/b978-0-12-814225-7.00004-8⟩

Chapitre d'ouvrage hal-04476956v1

Are Co-Culture Approaches Able to Improve Biological Functions of Bioartificial Livers?

V. Pandolfi , Ulysse Pereira , Murielle Dufresne , C. Legallais

Biomedical Membranes and (Bio)Artificial Organs, 2, WORLD SCIENTIFIC, pp.179-210, 2018, 978-981-3223-97-4. ⟨10.1142/9789813223974_0007⟩

Chapitre d'ouvrage hal-03411616v1

Hemodynamics inside autologous arteriovenous fistulas.

Iolanda Decorato , Zaher Kharboutly , Cécile Legallais , Anne-Virginie Salsac

Medical Devices Design in Cardiovascular Applications., 2013

Chapitre d'ouvrage hal-02019796v1

Microencapsulation d'hépatocytes pour le développement d'un système de suppléance hépatique.

A. Gautier , B. Carpentier , C. Legallais

Coord. Vandamme, Poncelet, Subra-Paternault. Microencapsulation : des sciences aux technologies, Lavoisier Editions Tec&Doc, pp.295-312, 2007

Chapitre d'ouvrage hal-00289971v1

Plasma Separation and Purification by Membrane

M.Y. Jaffrin , C. Legallais

Encyclopedia of Biomedical Engineering, Wiley-Interscience,, pp.2795-2804, 2006, 9780471740360. ⟨10.1002/9780471740360.ebs0935⟩

Chapitre d'ouvrage hal-00096787v1