Chaker El Kalamouni

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Publications

Targeted discovery of sesquiterpene indole alkaloids from Greenwayodendron suaveolens

Rany Mbeng Obame , Pierre Le Pogam , Karine Leblanc , Somia Rharrabti , Evodie Numbi Wa Ilunga et al.

Phytochemistry, 2026, 241, pp.114664. ⟨10.1016/j.phytochem.2025.114664⟩

Article dans une revue hal-05327820v1

Antiviral Strategies Against Dengue Virus: Recent Insights into Compounds Targeting Viral and Host Factors

Anjaranirina Koloina Rakotoarimanana , Patrick Carriere Richez , Voahangy Vestalys Ramanandraibe , Anne Bialecki , Chaker El Kalamouni

Current Topics in Microbiology and Immunology, 2025, Current Topics in Microbiology and Immunology, ⟨10.1007/82_2025_322⟩

Article dans une revue hal-05389964v1

Otitiglycomycins A and B: Glycolipids from the Strain Nocardia otitidiscavarum 20S-13 with Antiviral Activity against Zika Virus

Phuong-Y Mai , Élodie Marguerite , Jamal Ouazzani , Philippe Lopes , Pascal Retailleau et al.

Journal of Natural Products, 2025, 88 (2), pp.485-494. ⟨10.1021/acs.jnatprod.4c01302⟩

Article dans une revue hal-05033142v1
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Comptonellins A–H, Highly Potent Antiviral Ternatin-type Cyclopeptides from Comptonella drupacea

Cécile Apel , Juliano Haddad , Charline Herrscher , Clément Grisel , Justine Girard et al.

Journal of Natural Products, In press, ⟨10.1021/acs.jnatprod.5c00318⟩

Article dans une revue hal-05109539v1
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Phytochemical and Metabolomic Investigation of a Popular Traditional Plant from La Réunion: Psiloxylon mauritianum

Théo Ozga , Gaëtan Herbette , Patrick Carriere Richez , Patricia Clerc , Juliano Haddad et al.

Applied Sciences, 2025, 496, ⟨10.3390/app15020496⟩

Article dans une revue hal-05389901v1
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Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function

Gwenaëlle Jézéquel , Zoé Grimanelli , Carole Guimard , Joëlle Bigay , Juliano Haddad et al.

Journal of Medicinal Chemistry, 2024, ⟨10.1021/acs.jmedchem.4c01705⟩

Article dans une revue hal-04862839v1
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Analogues of Natural Macarangin B Display Potent Antiviral Activity and Better Metabolic Stability

Gwenaëlle Jézéquel , Jules Fargier , Joëlle Bigay , Joël Polidori , Justine Geslin et al.

ChemMedChem, 2024, 20 (9), ⟨10.1002/cmdc.202400978⟩

Article dans une revue hal-04862854v1

Combination of Machine Learning and Empirical Computation for the Structural Validation of Trirosaline, a Natural Trimeric Monoterpene Indole Alkaloid from Catharanthus roseus

Sarah Szwarc , Adrien Jagora , Séverine Derbré , Karine Leblanc , Somia Rharrabti et al.

Organic Letters, 2024, 26 (1), pp.274-279. ⟨10.1021/acs.orglett.3c03972⟩

Article dans une revue hal-04460068v1
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The Gold Nanoparticles-Functionalized with the Synthetic PADRE^S2P6 Peptide Can Be Useful for SARS-CoV-2 Detection

Charline Herrscher , Maroua Ben Haddada , Jessica Andries , Wildriss Viranaicken , Colette Cordonin et al.

Nanoarchitectonics, 2023, 4 (2), ⟨10.37256/nat.4220233692⟩

Article dans une revue hal-04512975v1
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New Phenolic Lipids from the Leaves of Clausena harmandiana Inhibit SARS-CoV-2 Entry into Host Cells

Marion Chambon , Charline Herrscher , Dana Al Halabi , Nathan François , Sandrine Belouzard et al.

Molecules, 2023, 28 (14), pp.5414. ⟨10.3390/molecules28145414⟩

Article dans une revue hal-04169811v1
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Daphnanes diterpenes from the latex of Hura crepitans L. and their PKCζ-dependent anti-proliferative activity on colorectal cancer cells

Elise Crossay , Valérie Jullian , Manon Trinel , David Sagnat , Dimitri Hamel et al.

Bioorganic and Medicinal Chemistry, 2023, 90, pp.117366. ⟨10.1016/j.bmc.2023.117366⟩

Article dans une revue hal-04244338v1
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Secondary metabolites as potential drug candidates against Zika virus, an emerging looming human threat: Current landscape, molecular mechanism and challenges ahead

Nabeelah Bibi Sadeer , Chaker El Kalamouni , Asaad Khalid , Ashraf N Abdalla , Gokhan Zengin et al.

Journal of Infection and Public Health, 2023, 16 (5), pp.754-770. ⟨10.1016/j.jiph.2023.03.008⟩

Article dans une revue hal-04515038v1

Rhizophora mucronata Lam., a halophyte from Mauritius Island, inhibits the entry of Zika virus in human cells (A549)- an in vitro and in silico analysis

Nabeelah Bibi Sadeer , Juliano Haddad , Mohammed Oday Ezzat , Philippe Desprès , Hassan Abdallah et al.

Journal of Biomolecular Structure and Dynamics, 2023, 41 (22), pp.12599-12609. ⟨10.1080/07391102.2023.2167115⟩

Article dans une revue hal-04514314v1
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Stability of Dengue 2 Nonstructural Glycoprotein 1 (NS1) Is Affected by the Nature of Basic Residue at Position NS1-324

Eva Ogire , Chaker El-Kalamouni , Philippe Desprès , Marjolaine Roche

Current Issues in Molecular Biology, 2023, 45 (2), pp.1644-1654. ⟨10.3390/cimb45020106⟩

Article dans une revue hal-04513028v1
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Antiviral Effect of Stenocline ericoides DC. and Stenocline inuloides DC., Two Flavonoid-Rich Endemic Plants from Madagascar, against Dengue and Zika Viruses

Fenia Ramiharimanana , Juliano Haddad , Maminiaina Andrianavalonirina , Cécile Apel , Florent Olivon et al.

Pharmaceuticals, 2022, 15 (12), pp.1500. ⟨10.3390/ph15121500⟩

Article dans une revue hal-04032891v1
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The SARS-CoV-2 spike residues 616/644 and 1138/1169 delineate two antibody epitopes in COVID-19 mRNA COMIRNATY vaccine (Pfizer/BioNTech)

Jessica Andries , Wildriss Viranaicken , Colette Cordonin , Charline Herrscher , Cynthia Planesse et al.

Scientific Reports, 2022, 12, pp.5999. ⟨10.1038/s41598-022-10057-7⟩

Article dans une revue hal-04090801v1
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Author Correction: The SARS-CoV-2 spike residues 616/644 and 1138/1169 delineate two antibody epitopes in COVID-19 mRNA COMIRNATY vaccine (Pfizer/BioNTech)

Jessica Andries , Wildriss Viranaicken , Colette Cordonin , Charline Herrscher , Cynthia Planesse et al.

Scientific Reports, 2022, 12 (1), ⟨10.1038/s41598-022-10885-7⟩

Article dans une revue hal-04542363v1

Endemic and Indigenous Plants from Mascarene Islands with Antiviral Propensities

Mahomoodally Mohamad Fawzi , Jugreet Bibi Sharmeen , Haddad Juliano , El Kalamouni Chaker

Current Drug Targets, 2022, 23 (1), pp.72-86. ⟨10.2174/1389450122666210824143910⟩

Article dans une revue hal-04515074v1
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In vitro bioactivities of extracts from tomato pomace

Aya Jamaleddine , Pascale De Caro , Jalloul Bouajila , Philippe Evon , Juliano G. Haddad et al.

Frontiers in Bioscience-Landmark, 2022, 27 (9), pp.259. ⟨10.31083/j.fbl2709259⟩

Article dans une revue hal-03780523v1
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Cranberry Pomace Extract Exerts Antiviral Activity against Zika and Dengue Virus at Safe Doses for Adult Zebrafish

Laura Tamkutė , Juliano G Haddad , Nicolas Diotel , Philippe Desprès , Petras Rimantas Venskutonis et al.

Viruses, 2022, 14 (5), pp.1101. ⟨10.3390/v14051101⟩

Article dans une revue hal-04227799v1
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Bruguiera gymnorhiza (L.) Lam. at the Forefront of Pharma to Confront Zika Virus and Microbial Infections—An In Vitro and In Silico Perspective

Nabeelah Bibi Sadeer , Juliano G Haddad , Mohammed Oday Ezzat , Philippe Desprès , Hassan H Abdallah et al.

Molecules, 2021, 26 (19), ⟨10.3390/molecules26195768⟩

Article dans une revue hal-04515127v1
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Mangiferin Rich Products from Aphloia theiformis (Vahl) Benn Leaves: Extraction, Fractionation, Phytochemical Characterization, and Antioxidant Properties

Dovilė Grauzdytė , Audrius Pukalskas , Chaker El Kalamouni , Petras Rimantas Venskutonis

Molecules, 2020, 25 (9), pp.2081. ⟨10.3390/molecules25092081⟩

Article dans une revue hal-02586623v1
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Papaya Fruit Pulp and Resulting Lactic Fermented Pulp Exert Antiviral Activity against Zika Virus

Juliano Haddad , Victoria Carcauzon , Omar El Kalamouni , Philippe Desprès , Cyrielle Garcia et al.

Microorganisms, 2020, 8 (9), pp.1257. ⟨10.3390/microorganisms8091257⟩

Article dans une revue hal-03066596v1
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Zika virus subversion of chaperone GRP78/BiP expression in A549 cells during UPR activation

Jonathan Turpin , Étienne Frumence , Wissal Harrabi , Juliano Haddad , Chaker El Kalamouni et al.

Biochimie, 2020, 175, pp.99-105. ⟨10.1016/j.biochi.2020.05.011⟩

Article dans une revue hal-03119668v1
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The Geraniin-Rich Extract from Reunion Island Endemic Medicinal Plant Phyllanthus phillyreifolius Inhibits Zika and Dengue Virus Infection at Non-Toxic Effect Doses in Zebrafish

Juliano Haddad , Dovilė Grauzdytė , Andrea Koishi , Wildriss Viranaicken , Petras Rimantas Venskutonis et al.

Molecules, 2020, 25 (10), pp.2316. ⟨10.3390/molecules25102316⟩

Article dans une revue hal-02586238v1
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The Polyphenol-Rich Extract from <i>Psiloxylon mauritianum</i>, an Endemic Medicinal Plant from Reunion Island, Inhibits the Early Stages of Dengue and Zika Virus Infection

Elodie Clain , Juliano Haddad , Andrea Koishi , Laura Sinigaglia , Walid Rachidi et al.

International Journal of Molecular Sciences, 2019, Natural Products against Viral Infections, 20 (8), pp.1860. ⟨10.3390/ijms20081860⟩

Article dans une revue hal-02383506v1
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Ayapana triplinervis Essential Oil and Its Main Component Thymohydroquinone Dimethyl Ether Inhibit Zika Virus at Doses Devoid of Toxicity in Zebrafish

Juliano Haddad , Morgane Picard , Sébastien Bénard , Claire Desvignes , Philippe Desprès et al.

Molecules, 2019, 24 (19), pp.3447. ⟨10.3390/molecules24193447⟩

Article dans une revue hal-02586306v1
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Doratoxylon apetalum, an Indigenous Medicinal Plant from Mascarene Islands, Is a Potent Inhibitor of Zika and Dengue Virus Infection in Human Cells

Juliano Haddad , Andrea Cristine Koishi , Arnaud Gaudry , Claudia Nunes Duarte dos Santos , Wildriss Viranaicken et al.

International Journal of Molecular Sciences, 2019, 20 (10), pp.2382. ⟨10.3390/ijms20102382⟩

Article dans une revue hal-02586355v1
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The Flavonoid Isoquercitrin Precludes Initiation of Zika Virus Infection in Human Cells

Arnaud Gaudry , Sandra Bos , Wildriss Viranaicken , Marjolaine Roche , Pascale Krejbich-Trotot et al.

International Journal of Molecular Sciences, 2018, 19 (4), pii: E1093. ⟨10.3390/ijms19041093⟩

Article dans une revue inserm-01767077v1
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Protective effects of Phyllanthus phillyreifolius extracts against hydrogen peroxide induced oxidative stress in HEK293 cells

Dovilė Grauzdytė , Audrius Pukalskas , Wildriss Viranaicken , Chaker El Kalamouni , Petras Rimantas Venskutonis

PLoS ONE, 2018, 13 (11), ⟨10.1371/journal.pone.0207672⟩

Article dans une revue hal-02983510v1

Antioxidant potential and phytochemical composition of extracts obtained from Phyllanthus phillyreifolius by different extraction methods

Dovilė Grauzdytė , Audrius Pukalskas , Chaker El Kalamouni , Petras Rimantas Venskutonis

Natural Product Research, 2018, 34 (5), pp.706-709. ⟨10.1080/14786419.2018.1493586⟩

Article dans une revue hal-04516409v1
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Extract from <i>Aphloia theiformis</i>, an edible indigenous plant from Reunion Island, impairs Zika virus attachment to the host cell surface

Elodie Clain , Laura Sinigaglia , Andrea Cristine Koishi , Olivier Gorgette , Gilles Gadea et al.

Scientific Reports, 2018, 8 (1), pp.10856. ⟨10.1038/s41598-018-29183-2⟩

Article dans une revue hal-02273495v1
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<i>In vitro</i> comparison of three common essential oils mosquito repellents as inhibitors of the Ross River virus

Miora Ralambondrainy , Essia Belarbi , Wildriss Viranaicken , Renata Baranauskienė , Petras Rimantas Venskutonis et al.

PLoS ONE, 2018, 13 (5), pp.14. ⟨10.1371/journal.pone.0196757⟩

Article dans une revue hal-04555624v1
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Subversion of the Heme Oxygenase-1 Antiviral Activity by Zika Virus

Chaker El Kalamouni , Étienne Frumence , Sandra Bos , Jonathan Turpin , Brice Nativel et al.

Viruses, 2018, New Advances on Zika Virus Research, 11 (1), ⟨10.3390/v11010002⟩

Article dans une revue hal-02981535v1
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The structural proteins of epidemic and historical strains of Zika virus differ in their ability to initiate viral infection in human host cells

Sandra Bos , Wildriss Viranaicken , Jonathan Turpin , Chaker El Kalamouni , Marjolaine Roche et al.

Virology, 2018, 516, pp.265 - 273. ⟨10.1016/j.virol.2017.12.003⟩

Article dans une revue hal-01702657v1
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Antioxidant and antimicrobial activities of the essential oil of Achillea millefolium L. Grown in France

Chaker El Kalamouni , Petras Venskutonis , Bachar Zebib , Othmane Merah , Christine Raynaud et al.

Medicines, 2017, Antimicrobial, Antioxidant and Anti-inflammatory Activities of Essential Oils), 4 (2), pp.30. ⟨10.3390/medicines4020030⟩

Article dans une revue hal-01607096v1

ClearColi BL21(DE3)-based expression of Zika virus antigens illustrates a rapid method of antibody production against emerging pathogens

Wildriss Viranaicken , Brice Nativel , Pascale Krejbich-Trotot , Wissal Harrabi , Sandra Bos et al.

Biochimie, 2017, 142 (9), pp.179 - 182. ⟨10.1016/j.biochi.2017.09.011⟩

Article dans une revue hal-01689690v1
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Recombinant Zika NS1 protein secreted from Vero cells is efficient for inducing production of immune serum against NS1 dimer

Wildriss Viranaicken , Alexia Ndebo , Sandra Bos , Philippe Souque , Gilles Gadea et al.

International Journal of Molecular Sciences, 2017, 19 (1), pp.38. ⟨10.3390/ijms19010038⟩

Article dans une revue hal-01703097v1

The South Pacific epidemic strain of Zika virus replicates efficiently in human epithelial A549 cells leading to IFN-β production and apoptosis induction

Étienne Frumence , Marjolaine Roche , Pascale Krejbich-Trotot , Chaker El Kalamouni , Brice Nativel et al.

Virology, 2016, 493, pp.217-226. ⟨10.1016/j.virol.2016.03.006⟩

Article dans une revue hal-01980899v1
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The growth of arthralgic Ross River virus is restricted in human monocytic cells

Pascale Krejbich-Trotot , Essia Belarbi , Miora Ralambondrainy , Chaker El Kalamouni , Wildriss Viranaicken et al.

Virus Research, 2016, 225, pp.64-68. ⟨10.1016/j.virusres.2016.09.007⟩

Article dans une revue inserm-01375991v2

Specialized metabolites with antiviral properties from a vietnamese plant : isolation and synthesis

Linh Hoang Phan , Bastien Petit , Juliano G Haddad , Chaker El Kalamouni , Xavier Cachet et al.

6ème Symposium AFERP, Jul 2023, Saclay, France

Poster de conférence hal-04258441v1

Synthesis and evaluation of a natural cyclopeptide

Clément Grisel , Prisca Lagardère , Cécile Apel , Marc Litaudon , Charline Herrscher et al.

30th Young Research Fellows Meeting, Feb 2023, Paris, France

Poster de conférence hal-04400682v1

Specialized metabolites with antiviral properties from a Vietnamese plant: isolation & synthesis

Linh Phan , Bastien Petit , Juliano Haddad , Chaker El Kalamouni , Karine Seron et al.

Journée de l’école doctorale Innovation Thérapeutique : du Fondamentale à l'Appliqué, Jun 2023, Orsay, France

Poster de conférence hal-04401065v1

Synthesis and evaluation of a natural cyclopeptide

Clément Grisel , Prisca Lagardère , Cécile Apel , Marc Litaudon , Charline Herrscher et al.

Journée de l’école doctorale Innovation Thérapeutique : du Fondamental à l'Appliqué 2023, Jun 2023, Orsay, France

Poster de conférence hal-04401087v1

Specialized metabolites with antiviral properties from a Vietnamese plant: isolation & synthesis

Linh Phan , Bastien Petit , Juliano Haddad , Chaker El Kalamouni , Karine Seron et al.

6ème symposium international de l’AFERP, Jul 2023, Orsay, France

Poster de conférence hal-04401116v1

Synthesis and evaluation of antiviral cyclopeptides isolated from a tropical plant

Clément Grisel , Prisca Lagardère , Cécile Apel , Marc Litaudon , Charline Herrscher et al.

23ème reunion du Groupement Français des Peptides et Protéines (GFPP), Sep 2023, Fournols, France

Poster de conférence hal-04401150v1

Medicinal plants as promising source of natural antiviral substances against Zika virus

Juliano Haddad , Gilles Gadea , Philippe Desprès , Chaker El Kalamouni

Zika Virus Impact, Diagnosis, Control, and Models, Volume 2: The Neuroscience of Zika, Elsevier, pp.397-407, 2021, 978-0-12-820267-8. ⟨10.1016/B978-0-12-820267-8.00038-8⟩

Chapitre d'ouvrage hal-04190549v1