Christian Specht

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Publications

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Single molecule counting detects low-copy glycine receptors in hippocampal and striatal synapses

Serena Camuso , Yana Vella , Souad Youjil Abadi , Clémence Mille , Bert Brône et al. Article dans une revue hal-05446349v1
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Competition between glycine and GABAA receptors for gephyrin controls their equilibrium populations at inhibitory synapses

Dorota Kostrz , Stephanie A Maynard , Serena Camuso , Clemens Schulte , François Laurent et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025, 122 (52), pp.e2500226122. ⟨10.1073/pnas.2500226122⟩

Article dans une revue hal-05446453v2
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Role of the Glycine Receptor β Subunit in Synaptic Localization and Pathogenicity in Severe Startle Disease

Anna-Lena Wiessler , Ann-Sofie Hasenmüller , Isabell Fuhl , Clémence Mille , Orlando Cortes Campo et al.

Journal of Neuroscience, 2023, 44 (2), pp.e0837232023. ⟨10.1523/jneurosci.0837-23.2023⟩

Article dans une revue hal-05446412v1
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Simulation-based inference for non-parametric statistical comparison of biomolecule dynamics

Hippolyte Verdier , François Laurent , Alhassan Cassé , Christian L. Vestergaard , Christian Specht et al.

PLoS Computational Biology, 2023, 19 (2), pp.e1010088. ⟨10.1371/journal.pcbi.1010088⟩

Article dans une revue hal-03876446v2
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A Versatile Synthetic Affinity Probe Reveals Inhibitory Synapse Ultrastructure and Brain Connectivity**

Vladimir Khayenko , Clemens Schulte , Sara L Reis , Orly Avraham , Cataldo Schietroma et al.

Angewandte Chemie, 2022, 134 (30), ⟨10.1002/ange.202202078⟩

Article dans une revue (data paper) hal-04252753v1
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A Versatile Synthetic Affinity Probe Reveals Inhibitory Synapse Ultrastructure and Brain Connectivity**

Vladimir Khayenko , Clemens Schulte , Sara Reis , Orly Avraham , Cataldo Schietroma et al.

Angewandte Chemie International Edition, 2022, 61 (30), ⟨10.1002/anie.202202078⟩

Article dans une revue (data paper) hal-04252751v1
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The α3 subunit of GABAA receptors promotes formation of inhibitory synapses in the absence of collybistin

Sven Wagner , Choongku Lee , Lucia Rojas , Christian G Specht , Jeongseop Rhee et al.

Journal of Biological Chemistry, 2021, 296, pp.100709. ⟨10.1016/j.jbc.2021.100709⟩

Article dans une revue (data paper) hal-04252772v1
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Differential regulation of glycinergic and GABAergic nanocolumns at mixed inhibitory synapses

Xiaojuan Yang , Hervé Le Corronc , Pascal Legendre , Antoine Triller , Christian G Specht

EMBO Reports, 2021, 22 (7), pp.e52154. ⟨10.15252/embr.202052154⟩

Article dans une revue hal-03941187v1
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Reciprocal stabilization of glycine receptors and gephyrin scaffold proteins at inhibitory synapses

Thomas Chapdelaine , Vincent Hakim , Antoine Triller , Jonas Ranft , Christian G Specht

Biophysical Journal, 2021, 120 (5), pp.805-817. ⟨10.1016/j.bpj.2021.01.024⟩

Article dans une revue hal-03448374v1
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A Quantitative Perspective of Alpha-Synuclein Dynamics – Why Numbers Matter

Christian G Specht

Frontiers in Synaptic Neuroscience, 2021, 13 (3), pp.497-502. ⟨10.3389/fnsyn.2021.753462⟩

Article dans une revue (article de synthèse) hal-04252766v1
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Identification of a stereotypic molecular arrangement of endogenous glycine receptors at spinal cord synapses

Stephanie A Maynard , Philippe Rostaing , Natascha Schaefer , Olivier Gemin , Adrien Candat et al.

eLife, 2021, 10, ⟨10.7554/elife.74441⟩

Article dans une revue hal-04252748v1
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Fractional occupancy of synaptic binding sites and the molecular plasticity of inhibitory synapses

Christian Specht

Neuropharmacology, 2020, 169, pp.107493. ⟨10.1016/j.neuropharm.2019.01.008⟩

Article dans une revue (article de synthèse) hal-04252770v1
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cAMP-EPAC-Dependent Regulation of Gephyrin Phosphorylation and GABA A R Trapping at Inhibitory Synapses

Fumihiro Niwa , Angela Patrizio , Antoine Triller , Christian G Specht Article dans une revue (data paper) hal-04252754v1
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Subsynaptic Domains in Super-Resolution Microscopy: The Treachery of Images

Xiaojuan Yang , Christian G Specht

Frontiers in Molecular Neuroscience, 2019, 12, ⟨10.3389/fnmol.2019.00161⟩

Article dans une revue (article de synthèse) hal-04252776v1
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Sequences Flanking the Gephyrin-Binding Site of GlyRβ Tune Receptor Stabilization at Synapses

Nora Grünewald , Audric Jan , Charlotte Salvatico , Vanessa Kress , Marianne Renner et al.

eNeuro, 2018, 5 (1), pp.ENEURO.0042-17.2018. ⟨10.1523/eneuro.0042-17.2018⟩

Article dans une revue hal-03974010v1
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Sequences Flanking the Gephyrin-Binding Site of GlyRβ Tune Receptor Stabilization at Synapses

Nora Grünewald , Audric Jan , Charlotte Salvatico , Vanessa Kress , Marianne Renner et al.

eNeuro, 2018, 5 (1), pp.ENEURO.0042-17.2018. ⟨10.1523/ENEURO.0042-17.2018⟩

Article dans une revue hal-04252750v1
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The Role of Synaptopodin in Membrane Protein Diffusion in the Dendritic Spine Neck

Lili Wang , Andréa Dumoulin , Marianne Renner , Antoine Triller , Christian Specht

PLoS ONE, 2016, 11 (2), pp.e0148310. ⟨10.1371/journal.pone.0148310⟩

Article dans une revue (data paper) hal-04252773v1
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Super-Resolution Dynamic Imaging of Dendritic Spines Using a Low-Affinity Photoconvertible Actin Probe

Ignacio Izeddin , Christian G Specht , Mickaël Lelek , Xavier Darzacq , Antoine Triller et al.

PLoS ONE, 2011, 6 (1), pp.e15611. ⟨10.1371/journal.pone.0015611⟩

Article dans une revue pasteur-02081263v1