Christina Sizun

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Publications

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Cyclodextrin-based formulations for delivering broad-spectrum nerve agent antidote to the central nervous system: stability, physicochemical characterization and application in a human blood–brain barrier model

Léa Thiberville , Vincent Faivre , Christina Sizun , Marie-Pierre Dehouck , Christophe Landry et al.
International Journal of Pharmaceutics, 2025, 674, pp.125505. ⟨10.1016/j.ijpharm.2025.125505⟩
Article dans une revue hal-05017548 v1
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Development of nanoparticles based on amphiphilic cyclodextrins for the delivery of active substances

Luc Augis , Ingeborg Nerbø Reiten , Jan-Lukas Førde , Juan Casas-Solvas , Christina Sizun et al.
International Journal of Pharmaceutics, 2024, 651, pp.123723. ⟨10.1016/j.ijpharm.2023.123723⟩
Article dans une revue hal-04366812 v1
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Hydrophobic binary mixtures containing amphotericin B as lipophilic solutions for the treatment of cutaneous leishmaniasis

Luc Augis , Canh Hung Nguyen , Cécile Ciseran , András Wacha , Françoise Mercier-Nomé et al.
International Journal of Pharmaceutics, 2024, 662, pp.124486. ⟨10.1016/j.ijpharm.2024.124486⟩
Article dans une revue hal-04660063 v1
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Structural transitions in TCTP tumor protein upon binding to the anti-apoptotic protein family member Mcl-1

Florian Malard , Christina Sizun , Aurélien Thureau , Ludovic Carlier , Ewen Lescop
Journal of Biological Chemistry, 2023, 299 (7), pp.104830. ⟨10.1016/j.jbc.2023.104830⟩
Article dans une revue hal-04208651 v1
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Hardening of Respiratory Syncytial Virus Inclusion Bodies by Cyclopamine Proceeds through Perturbation of the Interactions of the M2-1 Protein with RNA and the P Protein

Cédric Diot , Charles-Adrien Richard , Jennifer Risso-Ballester , Davy Martin , Jenna Fix et al.
International Journal of Molecular Sciences, 2023, 24 (18), pp.13862. ⟨10.3390/ijms241813862⟩
Article dans une revue hal-04239191 v1
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Investigation of the Fuzzy Complex between RSV Nucleoprotein and Phosphoprotein to Optimize an Inhibition Assay by Fluorescence Polarization

Silva Khodjoyan , Deborha Morissette , Fortune Hontonnou , Luis Checa Ruano , Charles-Adrien Richard et al.
International Journal of Molecular Sciences, 2023, 24 (1), pp.569. ⟨10.3390/ijms24010569⟩
Article dans une revue hal-04012024 v1
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Biophysical Reviews’ “Meet the Editors Series”: a profile of Christina Sizun

Christina Sizun
Biophysical Reviews, 2023, 15 (3), pp.301-304. ⟨10.1007/s12551-023-01071-8⟩
Article dans une revue hal-04256992 v1
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Iron insertion at the assembly site of the ISCU scaffold protein is a conserved process initiating Fe–S cluster biosynthesis

Batoul Srour , Sylvain Gervason , Maren Hellen Hoock , Beata Monfort , Kristian Want et al.
Journal of the American Chemical Society, 2022, 144 (38), pp.17496 - 17515. ⟨10.1021/jacs.2c06338⟩
Article dans une revue hal-03837292 v1
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Respiratory Syncytial Virus NS1 Protein Targets the Transactivator Binding Domain of MED25

Jiawei Dong , Vincent Basse , Maxime Bierre , Andressa Peres de Oliveira , Pierre-Olivier Vidalain et al.
Journal of Molecular Biology, 2022, 434 (19), pp.167763. ⟨10.1016/j.jmb.2022.167763⟩
Article dans une revue hal-03834936 v1
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A Structural and Dynamic Analysis of the Partially Disordered Polymerase-Binding Domain in RSV Phosphoprotein

Christophe Cardone , Claire-Marie Caseau , Benjamin Bardiaux , Aurélien Thureaux , Marie Gallou et al.
Biomolecules, 2021, 11 (8), ⟨10.3390/biom11081225⟩
Article dans une revue hal-03321817 v1
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Tetramerization of Phosphoprotein Is Essential for Respiratory Syncytial Virus Budding while Its N-Terminal Region Mediates Direct Interactions with the Matrix Protein

Monika Bajorek , Marie Galloux , Charles-Adrien Richard , Or Szekely , Rina Rosenzweig et al.
Journal of Virology, 2021, 95, ⟨10.1128/jvi.02217-20⟩
Article dans une revue hal-04635668 v2
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Pneumoviral Phosphoprotein, a Multidomain Adaptor-Like Protein of Apparent Low Structural Complexity and High Conformational Versatility

Christophe Cardone , Claire-Marie Caseau , Nelson Pereira , Christina Sizun
International Journal of Molecular Sciences, 2021, 22 (4), pp.1537. ⟨10.3390/ijms22041537⟩
Article dans une revue hal-03319031 v1
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Interactions between the nucleoprotein and the phosphoprotein of pneumoviruses: structural insight for rational design of antivirals

Hortense Decool , Lorène Gonnin , Irina Gutsche , Christina Sizun , Jean-François Eléouët et al.
Viruses, 2021, 13 (12), pp.2449. ⟨10.3390/v13122449⟩
Article dans une revue hal-03520624 v1
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A seven-residue deletion in PrP leads to generation of a spontaneous prion formed from C-terminal C1 fragment of PrP

Carola Munoz-Montesino , Djabir Larkem , Clément Barbereau , Angélique Igel-Egalon , Sandrine Truchet et al.
Journal of Biological Chemistry, 2020, 295 (41), pp.14025-14039. ⟨10.1074/jbc.RA120.014738⟩
Article dans une revue hal-02984242 v1
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Cyclodextrin Complexation Studies as the First Step for Repurposing of Chlorpromazine

Zhiqiang Wang , David Landy , Christina Sizun , Christine Cézard , Audrey Solgadi et al.
International Journal of Pharmaceutics, 2020, 584, pp.119391. ⟨10.1016/j.ijpharm.2020.119391⟩
Article dans une revue hal-02885940 v1
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Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin

Sylvain Gervason , Djabir Larkem , Amir Ben Mansour , Thomas Botzanowski , Christina S Müller et al.
Nature Communications, 2019, 10, pp.3566. ⟨10.1038/s41467-019-11470-9⟩
Article dans une revue hal-02276889 v1
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RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription

Charles-Adrien Richard , Vincent Rincheval , Safa Lassoued , Jenna Fix , Christophe Cardone et al.
PLoS Pathogens, 2018, 14 (3), pp.e1006920. ⟨10.1371/journal.ppat.1006920⟩
Article dans une revue hal-01740353 v1
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The stress sigma factor of RNA polymerase RpoS/σ S is a solvent-exposed open molecule in solution

Paola Cavaliere , Sebastien Brier , Petr Filipenko , Christina Sizun , Bertrand Raynal et al.
Biochemical Journal, 2018, 475 (1), pp.341 - 354. ⟨10.1042/BCJ20170768⟩
Article dans une revue pasteur-01685123 v1
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A stretch of residues within the protease-resistant core is not necessary for prion structure and infectivity

Carola Munoz-Montesino , Christina Sizun , Mohammed Moudjou , Laetitia Herzog , Fabienne Reine et al.
Prion, 2017, 11 (1), pp.25-30. ⟨10.1080/19336896.2016.1274851⟩
Article dans une revue hal-01603861 v1
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New insights into structural disorder in human respiratory syncytial virus phosphoprotein and implications for binding of protein partners

Nelson Pereira , Christophe Cardone , Safa Lassoued , Marie Galloux , Jenna Fix et al.
Journal of Biological Chemistry, 2017, 292 (6), pp.2120-2131. ⟨10.1074/jbc.M116.765958⟩
Article dans une revue hal-01605660 v1

Generating Bona Fide Mammalian Prions with Internal Deletions

Carola Munoz Montesino , Christina Sizun , Mohammed Moudjou , Laetitia Herzog , Fabienne Reine et al.
Journal of Virology, 2016, 90 (15), pp.6963-6975. ⟨10.1128/JVI.00555-16⟩
Article dans une revue hal-02638780 v1
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Binding interface between the Salmonella σ(S)/RpoS subunit of RNA polymerase and Crl: hints from bacterial species lacking crl.

Paola Cavaliere , Christina Sizun , Fabienne Levi-Acobas , Mireille Nowakowski , Véronique Monteil et al.
Scientific Reports, 2015, 5, pp.13564. ⟨10.1038/srep13564⟩
Article dans une revue pasteur-01392714 v1

Resonance assignment of the ribosome binding domain of E. coli ribosomal protein S1.

Pierre Giraud , Jean-Bernard Créchet , Marc Uzan , François Bontems , Christina Sizun
Biomolecular NMR Assignments, 2015, 9 (1), pp.107-111
Article dans une revue hal-01138275 v1

A Well-Balanced Preexisting Equilibrium Governs Electron Flux Efficiency of a Multidomain Diflavin Reductase

Oriane Frances , Fataneh Fatemi , Denis Pompon , Eric Guittet , Christina Sizun et al.
Biophysical Journal, 2015, 108 (6), pp.1527-1536. ⟨10.1016/j.bpj.2015.01.032⟩
Article dans une revue hal-01142871 v1
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1H, 13C and 15N resonance assignments of σS activating protein Crl from Salmonella enterica serovar Typhimurium

Paola Cavaliere , Françoise Norel , Christina Sizun
Biomolecular NMR Assignments, 2015, 9 (2), pp.397 - 401. ⟨10.1007/s12104-015-9617-z⟩
Article dans une revue pasteur-01413051 v1

A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of Human Respiratory Syncytial Virus

Mohamed Ouizougun-Oubari , Nelson Pereira , Bogdan Tarus , Marie Galloux , Safa Lassoued et al.
Journal of Virology, 2015, 89 (21), pp.11129-11143. ⟨10.1128/JVI.01612-15⟩
Article dans une revue pasteur-02546455 v1

Robust and low cost uniform (15)N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications.

Annalisa Meola , Célia Deville , Scott A Jeffers , Pablo Guardado-Calvo , Ieva Vasiliauskaite et al.
Journal of Structural Biology, 2014, 188 (1), pp.71-78. ⟨10.1016/j.jsb.2014.08.002⟩
Article dans une revue hal-01077147 v1
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Structure and Functional Analysis of the RNA- and Viral Phosphoprotein-Binding Domain of Respiratory Syncytial Virus M2-1 Protein.

Marie-Lise Blondot , Virginie Dubosclard , Jenna Fix , Safa Lassoued , Magali Aumont-Nicaise et al.
PLoS Pathogens, 2012, 8 (5), pp.e1002734. ⟨10.1371/journal.ppat.1002734⟩
Article dans une revue hal-00722058 v1

NMR structure of the human Mediator MED25 ACID domain.

François Bontems , Alexis Verger , Frédérique Dewitte , Zoé Lens , Jean-Luc Baert et al.
Journal of Structural Biology, 2011, 174 (1), pp.245-51. ⟨10.1016/j.jsb.2010.10.011⟩
Article dans une revue istex hal-00589014 v1

1H, 13C, and 15N resonance assignment of the central domain of hRSV transcription antitermination factor M2-1.

Virginie Dubosclard , Marie-Lise Blondot , Jean-François Eléouët , François Bontems , Christina Sizun
Biomolecular NMR Assignments, 2011, 5 (2), pp.237-239. ⟨10.1007/s12104-011-9308-3⟩
Article dans une revue hal-00634155 v1

S1 ribosomal protein functions in translation initiation and ribonuclease RegB activation are mediated by similar RNA/protein interactions. An NMR and SAXS analysis.

Pascale Aliprandi , Christina Sizun , Javier Perez , Fabien Mareuil , Sandrine Caputo et al.
Journal of Biological Chemistry, 2008, 283 (19), pp.13289-13301. ⟨10.1074/jbc.M707111200⟩
Article dans une revue hal-00254022 v1
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A simple genetic algorithm for the optimization of multidomain protein homology models driven by NMR residual dipolar coupling and small angle X-ray scattering data.

Fabien Mareuil , Christina Sizun , Javier Perez , Marc Schoenauer , Jean-Yves Lallemand et al.
European Biophysics Journal, 2007, 37 (1), pp.95-104. ⟨10.1007/s00249-007-0170-2⟩
Article dans une revue istex inria-00177279 v2