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Christophe leboeuf

Ingénieur de recherche en techniques biologiques
Current affiliations
  • 557826
  • 1005039
  • 481195
Researcher identifiers


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Mitapivat reprograms the RBC metabolome and improves anemia in a mouse model of hereditary spherocytosis

Alessandro Matte , Anand Wilson , Federica Gevi , Enrica Federti , Antonio Recchiuti
JCI Insight, 2023, 8 (20), ⟨10.1172/jci.insight.172656⟩
Journal articles hal-04256663v1
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A novel prognostic model based on four circulating miRNA in diffuse large B‐cell lymphoma: implications for the roles of MDSC and Th17 cells in lymphoma progression

Rui Sun , Zhong Zheng , Li Wang , Shu Cheng , Qing Shi
Molecular Oncology, 2021, 15 (1), pp.246-261. ⟨10.1002/1878-0261.12834⟩
Journal articles inserm-03343465v1
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BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome

Petra Gorombei , Fabien Guidez , Saravanan Ganesan , Mathieu Chiquet , Andrea Pellagatti
International Journal of Molecular Sciences, 2021, 22 (19), pp.10658. ⟨10.3390/ijms221910658⟩
Journal articles inserm-03945174v1
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The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a β-thalassemia mouse model

Alessandro Matte , Enrica Federti , Charles Kung , Penelope A Kosinski , Rohini Narayanaswamy
The Journal of clinical investigation, 2021, 131 (10), pp.e144206. ⟨10.1172/jci144206⟩
Journal articles inserm-03868319v1
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Increased risk of brain metastases among patients with melanoma and PROM2 expression in metastatic lymph nodes

Thuy Thi Nguyen , Guillaume Gapihan , Pauline Tetu , Frédéric Pamoukdjian , Morad El Bouchtaoui
Clinical and Translational Medicine, 2020, 10 (8), pp.e198. ⟨10.1002/ctm2.198⟩
Journal articles inserm-03344181v1
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Expression of angiopoietin-like 4 fibrinogen-like domain (cANGPTL4) increases risk of brain metastases in women with breast cancer

Tu Dao , Guillaume Gapihan , Christophe Leboeuf , Diaddin Hamdan , Jean-Paul Feugeas
Oncotarget, 2020, 11 (18), pp.1590-1602. ⟨10.18632/oncotarget.27553⟩
Journal articles inserm-03343188v1
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High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target

Guilhem Bousquet , Jean-Paul Feugeas , Yuchen Gu , Christophe Leboeuf , Morad El Bouchtaoui
Oncotarget, 2019, 10 (61), pp.6577-6588. ⟨10.18632/oncotarget.27312⟩
Journal articles hal-03892241v1
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Pulsed-laser irradiation of multifunctional gold nanoshells to overcome trastuzumab resistance in HER2-overexpressing breast cancer

Toni Nunes , Thomas Pons , Xue Hou , Khanh van Do , Benoît Caron
Journal of experimental & clinical cancer research, 2019, 38 (1), pp.306. ⟨10.1186/s13046-019-1305-x⟩
Journal articles inserm-02528127v1
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Genomics applied to the treatment of breast cancer

Diaddin Hamdan , Thi Thuy Nga Nguyen , Christophe Leboeuf , Solveig Meles , Anne Janin
Oncotarget, 2019, 10 (46), pp.4786-4801. ⟨10.18632/oncotarget.27102⟩
Journal articles inserm-02545178v1
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Evidence of Cardiovascular Calcification and Fibrosis in Pseudoxanthoma Elasticum Mouse Models Subjected to DOCA-Salt Hypertension

Loukman Omarjee , Charlotte Roy , Christophe Leboeuf , Julie Favre , Daniel Henrion
Scientific Reports, 2019, 9 (1), pp.16327. ⟨10.1038/s41598-019-52808-z⟩
Journal articles hal-02391178v1
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Re-exploring immune-related side effects of docetaxel in an observational study: Blood hypereosinophilia

Diaddin Hamdan , Christophe Leboeuf , Christine Le Foll , Guilhem Bousquet , Anne Janin
Cancer Medicine, 2019, 8 (5), pp.2005-2012. ⟨10.1002/cam4.2062⟩
Journal articles inserm-02124678v1
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A constitutional activating MET mutation makes the genetic link between malignancies and chronic inflammatory diseases

El Bouchtaoui Morad , Marcio Do Cruzeiro , Christophe Leboeuf , Irmine Loisel-Ferreira , Carèle Fédronie
Clinical Cancer Research, 2019, 25 (14), pp.4504-15. ⟨10.1158/1078-0432.CCR-18-3261⟩
Journal articles inserm-02124688v1
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Muc5b-deficient mice develop early histological lung abnormalities.

Hélène Valque , Valérie Gouyer , Catherine Duez , Christophe Leboeuf , Philippe Marquillies
Biology Open, 2019, 8, pp.bio046359. ⟨10.1242/bio.046359⟩
Journal articles hal-02359040v1
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Micromolecular methods for diagnosis and therapeutic strategy: a case study

Morad Elbouchtaoui , Iulia Tengher , Catherine Miquel , Charlotte Brugière , Amélie Benbara
Oncotarget, 2018, 9 (32), pp.22862-22869. ⟨10.18632/oncotarget.25161⟩
Journal articles inserm-03868258v1
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Targeting Cancer Stem Cells to Overcome Chemoresistance

Toni Nunes , Diaddin Hamdan , Christophe Leboeuf , Morad El Bouchtaoui , Guillaume Gapihan
International Journal of Molecular Sciences, 2018, 19 (12), pp.4036. ⟨10.3390/ijms19124036⟩
Journal articles inserm-02545148v1
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EGFR is involved in dermatofibrosarcoma protuberans progression to high grade sarcoma

Amélie Osio , Shuo Xu , Morad El Bouchtaoui , Christophe Leboeuf , Guillaume Gapihan
Oncotarget, 2018, 9 (9), pp.8478-8488. ⟨10.18632/oncotarget.23899⟩
Journal articles hal-03892082v1
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Targeting Cancer Stem Cells to Overcome Chemoresistance

Toni Nunes , Diaddin Hamdan , Christophe Leboeuf , Morad El Bouchtaoui , Guillaume Gapihan
International Journal of Molecular Sciences, 2018, 19 (12), pp.4036. ⟨10.3390/ijms19124036⟩
Journal articles inserm-02124684v1

Targeting autophagic cancer stem-cells to reverse chemoresistance in human triple negative breast cancer

Guilhem Bousquet , Morad El Bouchtaoui , Tan Sophie , Christophe Leboeuf , Cédric de Bazelaire
Oncotarget, 2017, 8 (21), pp.35205-35221. ⟨10.18632/oncotarget.16925⟩
Journal articles hal-03892271v1
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Increased risk of brain metastases in women with breast cancer and p16 expression in metastatic lymph-nodes

Elise Furet , Morad El Bouchtaoui , Jean-Paul Feugeas , Catherine Miquel , Christophe Leboeuf
Oncotarget, 2017, 8 (23), pp.37332-37341. ⟨10.18632/oncotarget.16953⟩
Journal articles hal-03892340v1

A digestive allergic reaction with hypereosinophilia imputable to docetaxel in a breast cancer patient: a case report

Diaddin Hamdan , Christophe Leboeuf , Cathy Pereira , Nathalie Jourdan , Laurence Verneuil
BMC Cancer, 2015
Journal articles inserm-01397050v1

Stem cells increase in numbers in perinecrotic areas in human renal cancer

Mariana Varna , Guillaume Gapihan , Jean-Paul Feugeas , Philippe Ratajczak , Sophie Tan
Clinical Cancer Research, 2015, 21 (4), pp.916--924. ⟨10.1158/1078-0432.CCR-14-0666⟩
Journal articles hal-02142795v1
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Tracking sub-clonal TP53 mutated tumor cells in human metastatic renal cell carcinoma

Guilhem Bousquet , Morad El Bouchtaoui , Christophe Leboeuf , Maxime Battistella , Mariana Varna
Oncotarget, 2015, 6 (22), pp.19279-19289. ⟨10.18632/oncotarget.4220⟩
Journal articles inserm-03874928v1

In vivo uptake and cellular distribution of gold nanoshells in a preclinical model of xenografted human renal cancer

Mariana Pannerec-Varna , Philippe Ratajczak , Guilhem Bousquet , Irmine Ferreira , Christophe Leboeuf
Gold Bulletin : The journal of gold science, technology and applications , 2013, 46 (4), pp.257-265. ⟨10.1007/s13404-013-0115-8⟩
Journal articles hal-02316735v1

Differential regulation of sunitinib targets predicts its tumor-type-specific effect on endothelial and/or tumor cell apoptosis

Guilhem Bousquet , Mariana Varna , Irmine Ferreira , Li Wang , Pierre Mongiat-Artus
Cancer Chemotherapy and Pharmacology, 2013, 72 (6), pp.1183--1193. ⟨10.1007/s00280-013-2300-0⟩
Journal articles hal-02142772v1
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Donor-Derived Keratinocytes in Actinic Keratosis and Squamous Cell Carcinoma in Patients with Kidney Transplant

Laurence Verneuil , Mariana Varna , Christophe Leboeuf , Louis François Plassa , Morad Elbouchtaoui
Journal of Investigative Dermatology, 2012, 133 ((4)), pp.1108-1111. ⟨10.1038/jid.2012.422⟩
Journal articles inserm-01397779v1
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BCL2 expression in CD105 positive neoangiogenic cells and tumor progression in angioimmunoblastic T-cell lymphoma.

Philippe Ratajczak , Christophe Leboeuf , Li Wang , Josette Brière , Irmine Loisel-Ferreira
Modern Pathology, 2012, 25 (6), pp.805-14. ⟨10.1038/modpathol.2012.1⟩
Journal articles inserm-00682931v1

Les avortements infectieux chez les bovins vers une démarche standardisée d'investigation

Raphaël R. Guatteo , Philippe Nicollet , Eric Ledréan , Barbara Vassiloglou , Jean-Luc Cheval
Le Point vétérinaire, 2011, pp.66-71
Journal articles hal-02647190v1
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Bevacizumab potentiates chemotherapeutic effect on T-leukemia/lymphoma cells by direct action on tumor endothelial cells.

Li Wang , Wen-Yu Shi , Fan Yang , Wei Tang , Guillaume Gapihan
Haematologica, 2011, 96 (6), pp.927-31. ⟨10.3324/haematol.2010.037689⟩
Journal articles inserm-00741102v1
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Th17/Treg ratio in human graft-versus-host disease.

Philippe Ratajczak , Anne Janin , Regis Peffault de Latour , Christophe Leboeuf , Allison Desveaux
Blood, 2010, 116 (7), pp.1165-71. ⟨10.1182/blood-2009-12-255810⟩
Journal articles inserm-00498759v1
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p53 dependent cell-cycle arrest triggered by chemotherapy in xenografted breast tumors.

Mariana Varna , Jacqueline Lehmann-Che , Elisabeth Turpin , Elizabetha Marangoni , Morad El-Bouchtaoui
International Journal of Cancer, 2009, 124 (4), pp.991-7. ⟨10.1002/ijc.24049⟩
Journal articles inserm-00498765v1
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Endothelial cell apoptosis in severe drug-induced bullous eruptions.

Laurence Verneuil , Philippe Ratajczak , Chloé Allabert , Christophe Leboeuf , François Comoz
British Journal of Dermatology, 2009, 161 (6), pp.1371-5. ⟨10.1111/j.1365-2133.2009.09357.x⟩
Journal articles inserm-00498764v1
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Donor-derived oral squamous cell carcinoma after allogeneic bone marrow transplantation.

Anne Janin , Hideyuki Murata , Christophe Leboeuf , Jean-Michel Cayuela , Eliane Gluckman
Blood, 2009, 113 (8), pp.1834-40. ⟨10.1182/blood-2008-07-171702⟩
Journal articles inserm-00498762v1

Value of cytogenetic analysis in the treatment of dermatofibrosarcoma protuberans.

Delphine Kerob , Florence Pedeutour , Christophe Leboeuf , Olivier Verola , Eric de Kerviler
Journal of Clinical Oncology, 2008, 26 (10), pp.1757-9. ⟨10.1200/JCO.2007.14.7330⟩
Journal articles hal-00320060v1

Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease

Nathalie Sabaa , Lucia De Franceschi , Philippe Bonnin , Yves Castier , Giorgio Malpeli
Journal of Clinical Investigation, 2008, 118 (5), pp.1924--1933. ⟨10.1172/JCI33308⟩
Journal articles hal-02142776v1

The dual endothelin receptor antagonist bosentan prevents the acute sickle cell-related hypoxic lung and kidney injury in transgenic SAD mice

Nathalie Sabaa , Lucia De Franceschi , Philippe Bonnin , Giorgio Malpeli , Stéphane Germain
Blood, 2006, 108 (11), pp.206A
Journal articles hal-02142743v1