CJ

Claire JANOIR

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Publications

The state of play of rodent models for the study of Clostridioides difficile infection

Anaïs Brosse , Héloïse Coullon , Claire Janoir , Séverine Péchiné

Journal of Medical Microbiology, 2024, 73 (7), ⟨10.1099/jmm.0.001857⟩

Article dans une revue hal-04704094v1
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Dual RNA-seq study of the dynamics of coding and non-coding RNA expression during Clostridioides difficile infection in a mouse model

Victor Kreis , Claire Toffano-Nioche , Cécile Denève-Larrazet , Jean-Christophe Marvaud , Julian R Garneau et al.

mSystems, 2024, Host-Microbial Interactions, 9 (12), pp.e0086324. ⟨10.1128/msystems.00863-24⟩

Article dans une revue hal-04823328v1
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Polysaccharide II Surface Anchoring, the Achilles’ Heel of Clostridioides difficile

Jeanne Malet-Villemagne , Liang Yucheng , Laurent Evanno , Sandrine Denis-Quanquin , Jean-Emmanuel Hugonnet et al.

Microbiology Spectrum, In press, ⟨10.1128/spectrum.04227-22⟩

Article dans une revue hal-04009559v1
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Inhibition of In Vitro Clostridioides difficile Biofilm Formation by the Probiotic Yeast Saccharomyces boulardii CNCM I-745 through Modification of the Extracellular Matrix Composition

Pierre-Alexandre Lacotte , Alexis Simons , Sylvie Bouttier , Jeanne Malet-Villemagne , Valérie Nicolas et al.

Microorganisms, 2022, 10 (6), pp.1082. ⟨10.3390/microorganisms10061082⟩

Article dans une revue hal-04174302v1
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Impact of Subinhibitory Concentrations of Metronidazole on Morphology, Motility, Biofilm Formation and Colonization of Clostridioides difficile

Tri-Hanh-Dung Doan , Marie-Françoise Bernet-Camard , Sandra Hoÿs , Claire Janoir , Séverine Péchiné

Antibiotics, 2022, 11, pp.1-16. ⟨10.3390/antibiotics11050624⟩

Article dans une revue hal-03808252v1
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Characterization of Non-Toxigenic Clostridioides difficile Strains Isolated from Preterm Neonates and In Vivo Study of Their Protective Effect

Jeanne Couturier , Léa Franconeri , Claire Janoir , Laurent Ferraris , Rabab Syed-Zaidi et al.

Journal of Clinical Medicine, 2020, 9 (11), pp.3650. ⟨10.3390/jcm9113650⟩

Article dans une revue hal-03060628v1
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Peptidoglycan analysis reveals that synergistic deacetylase activity in vegetative Clostridium difficile impacts the host response

Héloïse Coullon , Aline Rifflet , Richard Wheeler , Claire Janoir , Ivo G Boneca et al.

Journal of Biological Chemistry, 2020, 295 (49), pp.16785-16796. ⟨10.1074/jbc.RA119.012442⟩

Article dans une revue hal-03332384v1

Molecular features of lipoprotein CD0873: A potential vaccine against the human pathogen Clostridioides difficile

William Bradshaw , Jean-François Bruxelle , Andrea Kovacs-Simon , Nicholas Harmer , Claire Janoir et al.

Journal of Biological Chemistry, 2019, 294 (43), pp.15850-15861. ⟨10.1074/jbc.RA119.010120⟩

Article dans une revue hal-04437474v1
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Virulence of new variant strains of Clostridium difficile producing only toxin A or binary toxin in the hamster model

J.-C. Marvaud , S. Quevedo-Torres , C. Eckert , Claire Janoir , F. Barbut

New Microbes and New Infections, 2019, 32, pp.100590 -. ⟨10.1016/j.nmni.2019.100590⟩

Article dans une revue hal-03488275v1

2,4‐Disubstituted 5‐Nitroimidazoles Potent against Clostridium difficile

Cedric Spitz , Fanny Mathias , Séverine Péchiné , Tri Hanh Dung Doan , Jean Innocent et al.

ChemMedChem, 2019, 14 (5), pp.561-569. ⟨10.1002/cmdc.201800784⟩

Article dans une revue hal-02080163v1
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The Ser/Thr kinase PrkC participates in cell wall homeostasis and antimicrobial resistance in Clostridium difficile

Elodie Cuenot , Transito Garcia-Garcia , Thibaut Douche , Olivier Gorgette , Pascal Courtin et al.

Infection and Immunity, 2019, 87 (8), pp.e00005-19. ⟨10.1128/IAI.00005-19⟩

Article dans une revue pasteur-02164685v1
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Molecular features of lipoprotein CD0873: A potential vaccine against the human pathogen Clostridioides difficile

William Bradshaw , Jean-François Bruxelle , Andrea Kovacs-Simon , Nicholas Harmer , Claire Janoir et al.

Journal of Biological Chemistry, 2019, 294 (43), pp.15850-15861. ⟨10.1074/jbc.RA119.010120⟩

Article dans une revue hal-04353344v1

Molecular features of lipoprotein CD0873: A potential vaccine against the human pathogen Clostridioides difficile

William Bradshaw , Jean-François Bruxelle , Andrea Kovacs-Simon , Nicholas Harmer , Claire Janoir et al.

Journal of Biological Chemistry, 2019, 294 (43), pp.15850-15861. ⟨10.1074/jbc.RA119.010120⟩

Article dans une revue hal-04341886v1

2,4‐Disubstituted 5‐Nitroimidazoles Potent against Clostridium difficile

Cédric Spitz , Fanny Mathias , Séverine Péchiné , Tri Hanh Dung Doan , Jean Innocent et al.

ChemMedChem, 2019, 14 (5), pp.561-569. ⟨10.1002/cmdc.201800784⟩

Article dans une revue hal-04341841v1
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Clostridium difficile forms variable biofilms on abiotic surface

Véronique Pantaleon , Marc Monot , Catherine Eckert , Sandra Hoys , Anne Collignon et al.

Anaerobe, 2018, 53, pp.34-37. ⟨10.1016/j.anaerobe.2018.05.006⟩

Article dans une revue pasteur-02549240v1
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Protection against Clostridium difficile infection in a hamster model by oral vaccination using flagellin FliC-loaded pectin beads

J. F. Bruxelle , N. Tsapis , S. Hoys , A. Collignon , Claire Janoir et al.

Vaccine, 2018, 36 (40), pp.6017-6021. ⟨10.1016/j.vaccine.2018.08.013⟩

Article dans une revue hal-02323737v1
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Inhibitory Effect of Ursodeoxycholic Acid on Clostridium difficile Germination Is Insufficient to Prevent Colitis: A Study in Hamsters and Humans

Lola-Jade Palmieri , Dominique Rainteau , Harry Sokol , Laurent Beaugerie , Marie Dior et al.

Frontiers in Microbiology, 2018, 9, pp.2849. ⟨10.3389/fmicb.2018.02849⟩

Article dans une revue hal-01944522v1
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N-Deacetylases required for muramic-δ-lactam production are involved in Clostridium difficile sporulation, germination, and heat resistance

Héloïse Coullon , Aline Rifflet , Richard Wheeler , Claire Janoir , Ivo Gomperts Boneca et al.

Journal of Biological Chemistry, 2018, 293 (47), pp.18040-18054. ⟨10.1074/jbc.RA118.004273⟩

Article dans une revue hal-04374612v1

Targeting Clostridium difficile Surface Components to Develop Immunotherapeutic Strategies Against Clostridium difficile Infection

Séverine Péchiné , Jean Bruxelle , Claire Janoir , Anne Collignon

Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.01009⟩

Article dans une revue hal-04341878v1

Emerging monoclonal antibodies against Clostridium difficile infection

Séverine Péchiné , Claire Janoir , Anne Collignon

Expert Opinion on Biological Therapy, 2017, 17 (4), pp.415-427. ⟨10.1080/14712598.2017.1300655⟩

Article dans une revue (article de synthèse) hal-04342291v1

Clostridium difficile flagella induce a pro-inflammatory response in intestinal epithelium of mice in cooperation with toxins

Jameel Batah , Hussein Kobeissy , Phuong Trang Bui Pham , Cécile Denève-Larrazet , Sarah Kuehne et al.

Scientific Reports, 2017, 7 (1), pp. 3256. ⟨10.1038/s41598-017-03621-z⟩

Article dans une revue hal-04152694v1

Clostridium difficile flagella induce a pro-inflammatory response in intestinal epithelium of mice in cooperation with toxins

Jameel Batah , Hussein Kobeissy , Phuong Trang Bui Pham , Cécile Denève-Larrazet , Sarah Kuehne et al.

Scientific Reports, 2017, 7 (1), pp.3256. ⟨10.1038/s41598-017-03621-z⟩

Article dans une revue hal-04152950v1
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Biofilm Structures in a Mono-Associated Mouse Model of Clostridium difficile Infection

Anna P Soavelomandroso , Françoise Gaudin , Sandra Hoys , Valérie Nicolas , Gayatri Vedantam et al.

Frontiers in Microbiology, 2017, 8, ⟨10.3389/fmicb.2017.02086⟩

Article dans une revue (data paper) hal-04342298v1

The alternative sigma factor σ B plays a crucial role in adaptive strategies of Clostridium difficile during gut infection

Nicolas Kint , Claire Janoir , Marc Monot , Sandra Hoys , Olga Soutourina et al.

Environmental Microbiology, 2017, Special Issue on Pathogen and Antibiotic Resistance Ecology 19 (5), pp.1933 - 1958. ⟨10.1111/1462-2920.13696⟩

Article dans une revue pasteur-01613370v1
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Deciphering Adaptation Strategies of the Epidemic Clostridium difficile 027 Strain during Infection through In Vivo Transcriptional Analysis

Imad Kansau , Amira Barketi-Klai , Marc Monot , Sandra Hoys , Bruno Dupuy et al.

PLoS ONE, 2016, 11 (6), pp.e0158204. ⟨10.1371/journal.pone.0158204⟩

Article dans une revue pasteur-01370713v1
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The <em>Clostridium difficile</em> Protease Cwp84 Modulates both Biofilm Formation and Cell-Surface Properties

Véronique Pantaleon , Anna Philibertine Soavelomandroso , Sylvie Bouttier , Romain Briandet , Bryan Roxas et al.

PLoS ONE, 2015, 10 (4), ⟨10.1371/journal.pone.0124971⟩

Article dans une revue hal-02639033v1
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Adaptive Strategies and Pathogenesis of Clostridium difficile from In Vivo Transcriptomics

Claire Janoir , Cécile Denève , Sylvie Bouttier , Frédéric Barbut , Sandra Hoys et al.

Infection and Immunity, 2013, 81 (10), pp.3757-3769. ⟨10.1128/IAI.00515-13⟩

Article dans une revue hal-04152660v1

Encapsulation of Cwp84 into pectin beads for oral vaccination against Clostridium difficile

Chiara Sandolo , Séverine Péchiné , Alban Le Monnier , Sandra Hoys , Claire Janoir et al.

European Journal of Pharmaceutics and Biopharmaceutics, 2011, 79 (3), pp.566 - 573. ⟨10.1016/j.ejpb.2011.05.011⟩

Article dans une revue istex hal-02650812v1

A proposed nomenclature for cell wall proteins of Clostridium difficile

Robert P. Fagan , Claire Janoir , Anne Collignon , Paola Mastrantonio , Ian R. Poxton et al.

Journal of Medical Microbiology, 2011, 60 (8), pp.1225 - 1228. ⟨10.1099/jmm.0.028472-0⟩

Article dans une revue hal-02651126v1

Encapsulation of Cwp84 into pectin beads for oral vaccination against Clostridium difficile

Chiara Sandolo , Séverine Péchiné , Alban Le Monnier , Sandra Hoys , Claire Janoir et al.

European Journal of Pharmaceutics and Biopharmaceutics, 2011, 79 (3), pp.566-573. ⟨10.1016/j.ejpb.2011.05.011⟩

Article dans une revue istex hal-05463805v1

Immunization of hamsters against Clostridium difficile infection using the Cwp84 protease as an antigen

Séverine Péchiné , Cécile Denève , Alban Le Monnier , Sandra Hoys , Claire Janoir et al.

FEMS Immunology and Medical Microbiology, 2011, 63 (1), pp.73-81. ⟨10.1111/j.1574-695x.2011.00832.x⟩

Article dans une revue hal-05463807v1

Immunization of hamsters against Clostridium difficile infection using the Cwp84 protease as an antigen

Séverine Péchiné , Cécile Denève , Alban Le Monnier , Sandra Hoys , Claire Janoir et al.

FEMS Immunology and Medical Microbiology, 2011, 63 (1), pp.73 - 81. ⟨10.1111/j.1574-695X.2011.00832.x⟩

Article dans une revue hal-02648697v1

Effects of Subinhibitory Concentrations of Antibiotics on Colonization Factor Expression by Moxifloxacin-Susceptible and Moxifloxacin-Resistant Clostridium difficile Strains

Cecile Deneve , S. Bouttier , B. Dupuy , F. Barbut , A. Collignon et al.

Antimicrobial Agents and Chemotherapy, 2009, 53 (12), pp.5155-5162. ⟨10.1128/AAC.00532-09⟩

Article dans une revue pasteur-02444048v1

Identification and characterization of a fibronectin-binding protein from Clostridium difficile

Claire Hennequin , Claire Janoir , Marie-Claude Barc , Anne Collignon , Tuomo Karjalainen

Microbiology, 2003, 149 (10), pp.2779 - 2787. ⟨10.1099/mic.0.26145-0⟩

Article dans une revue hal-01899010v1

The Clostridioides difficile biofilm: myths and realities

Claire Janoir

IV INTERNATIONAL AND LATIN AMERICAN Clostridium difficile SYMPOSIUM, Nov 2023, Visioconférence, Brazil

Communication dans un congrès hal-04346702v1

Le polysaccharide II est essentiel à la mise en place de la surface de C. difficile

Jeanne Malet-Villemagne , Léa Huet , Claire Janoir , Isabelle Martin-Verstraete , Thomas Candela

Bactéries sporulantes pathogènes ou d'intérêt technologique BSPIT, Nov 2023, Paris, France

Communication dans un congrès hal-04341988v1

Session "Clostridioides... toujours difficile" : Comprendre les mécanismes à l’origine de sa virulence

Claire Janoir

42ème REUNION INTERDISCIPLINAIRE DE CHIMIOTHERAPIE ANTI-INFECTIEUSE, Dec 2022, Paris, France

Communication dans un congrès hal-04342324v1
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Colonization of the gut by Clostridioides difficile: the host, the bacteria and the microbiota

Claire Janoir

III INTERNATIONAL AND LATIN AMERICAN Clostridium difficile SYMPOSIUM, Sep 2021, Visioconférence, Brazil

Communication dans un congrès hal-04342309v1

Updates on the pathogenesis of Clostridium difficile infections: does in vivo biofilm formation play a role?

Claire Janoir

II International and Latin American Clostridium difficile Symposium, Jun 2019, Fortaleza, Brazil

Communication dans un congrès hal-04342082v1

In vivo visualization of Clostridium difficile and biofilms

Claire Janoir , Sylvie Bouttier

6th International Clostridium difficile Symposium, Sep 2018, Bled (Slovénie), Slovenia

Communication dans un congrès hal-04342002v1

Altered spore cortex impairs virulence in <i>C. difficile</i>

Héloïse Coullon , Aline Rifflet , Richard Wheeler , Claire Janoir , Ivo Boneca et al.

Bactéries Sporulantes Pathogènes ou d'Intérêt Technologique, INRAE, Mar 2018, Paris, France

Communication dans un congrès hal-04341916v1

Muramic-δ-lactams are involved in <i>C. difficile</i> sporulation, germination and virulence

Héloïse Coullon , Aline Rifflet , Richard Wheeler , Claire Janoir , Ivo Boneca et al.

International Clostridium difficile Symposium, Sep 2018, Bled, Slovenia

Communication dans un congrès hal-04341951v1

Physiopathologie de l’infection à C. difficile

Claire Janoir

2ème Journée du Groupe Français de Transplantation Fécale, GFTF, Jun 2018, Paris, France

Communication dans un congrès hal-04342051v1

Clostridium difficile infection mouse model for the analysis of natural systemic and mucosal immunity

A. Mizrahi , Gauthier Péan de Ponfilly , Sandra Hoÿs , Amandine Caillault , Justine Crestia et al.

RICAI, Dec 2018, Paris, France

Communication dans un congrès hal-04344585v1

Chapitre 3 : "Variation du microbiote intestinal selon l'âge et le sexe

Claire Janoir , Patricia Lepage

Elsevier. Microbiote intestinal et santé humaine, 2021, 978-2-294-76930-6

Chapitre d'ouvrage hal-04346723v1