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Danièle Noël

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Complex deformation of cartilage micropellets following mechanical stimulation promotes chondrocyte gene expression

Noémie Petitjean , Patrick Cañadas , Christian Jorgensen , Pascale Royer , Simon Le Floc’h
Current Stem Cell Research & Therapy, 2023, 14 (1), pp.226. ⟨10.1186/s13287-023-03459-5⟩
Journal articles hal-04458059v1
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Cartilage biomechanics: From the basic facts to the challenges of tissue engineering

Noémie Petitjean , Patrick Cañadas , Pascale Royer , Danièle Noël , Simon Le Floc’h
Journal of Biomedical Materials Research Part A, inPress, ⟨10.1002/jbm.a.37478⟩
Journal articles hal-03920499v1

Gelatin modified with alkoxysilanes (GelmSi) forms hybrid hydrogels for bioengineering applications

Matthieu Simon , Marie Maumus , Baptiste Legrand , Lilian Sole , Marjorie Dufaud
Biomaterials Advances, 2023, 147, pp.213321. ⟨10.1016/j.bioadv.2023.213321⟩
Journal articles hal-04025398v1
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Controlled Silylation of Polysaccharides: Attractive Building Blocks for Biocompatible Foams and Cell-Laden Hydrogels

Titouan Montheil , Laurine Raimond , Laurine Valot , Marie Maumus , Matthieu Simon
ACS Applied Polymer Materials, 2022, 4 (6), pp.4087-4097. ⟨10.1021/acsapm.1c01823⟩
Journal articles hal-03692906v1
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Hospitalizations for infections in primary Sjögren’s syndrome patients: a nationwide incidence study

Radjiv Goulabchand , Alain Makinson , Jacques Morel , Philine Witkowski-Durand-Viel , Nicolas Nagot
Annals of Medicine, 2022, 54 (1), pp.2672-2680. ⟨10.1080/07853890.2022.2126517⟩
Journal articles hal-03792560v1
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Silylated biomolecules: Versatile components for bioinks

Titouan Montheil , Matthieu Simon , Danièle Noël , Ahmad Mehdi , Gilles Subra
Frontiers in Bioengineering and Biotechnology, 2022, 10, pp.888437. ⟨10.3389/fbioe.2022.888437⟩
Journal articles hal-03810640v1
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Hospitalization Risks for Neurological Disorders in Primary Sjögren’s Syndrome Patients

Radjiv Goulabchand , Audrey Gabelle , Xavier Ayrignac , Nicolas Malafaye , Pierre Labauge
Journal of Clinical Medicine, 2022, 11 (7), pp.1979. ⟨10.3390/jcm11071979⟩
Journal articles hal-03639846v1
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Intra-articular delivery of full-length antibodies through the use of an in situ forming depot

Alexis Fayd'Herbe de Maudave , Wilhem Leconet , Karine Toupet , Michael Constantinides , Guillaume Bossis
Journal of Controlled Release, 2022, 341, pp.578-590. ⟨10.1016/j.jconrel.2021.12.010⟩
Journal articles hal-03563900v1
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3D bioprinting of articular cartilage: Recent advances and perspectives

Marjorie Dufaud , Lilian Solé , Marie Maumus , Matthieu Simon , Emeline Perrier-Groult
Bioprinting , 2022, 28, pp.e00253. ⟨10.1016/j.bprint.2022.e00253⟩
Journal articles hal-04041745v1
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miR-155 Contributes to the Immunoregulatory Function of Human Mesenchymal Stem Cells

Yves-Marie Pers , Claire Bony , Isabelle Duroux-Richard , Laurène Bernard , Marie Maumus
Frontiers in Immunology, 2021, 12, pp.624024. ⟨10.3389/fimmu.2021.624024⟩
Journal articles hal-03660057v1
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Lung Fibrosis Is Improved by Extracellular Vesicles from IFNγ-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis

Pauline Rozier , Marie Maumus , Alexandre Thibault Jacques Maria , Karine Toupet , Christian Jorgensen
Cells, 2021, 10 (10), pp.2727. ⟨10.3390/cells10102727⟩
Journal articles hal-03639272v1
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Mesenchymal stromal cells-derived extracellular vesicles alleviate systemic sclerosis via miR-29a-3p

Pauline Rozier , Marie Maumus , Alexandre Thibault Jacques Maria , Karine Toupet , Joséphine Lai-Kee-Him
Journal of Autoimmunity, 2021, 121, pp.102660. ⟨10.1016/j.jaut.2021.102660⟩
Journal articles hal-03655547v1
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A Collagen-Mimetic Organic-Inorganic Hydrogel for Cartilage Engineering

Laurine Valot , Marie Maumus , Luc Brunel , Jean Martínez , Muriel Amblard
Gels, 2021, 7 (2), pp.73. ⟨10.3390/gels7020073⟩
Journal articles hal-03264660v1
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Extracellular vesicles from mesenchymal stromal cells: Therapeutic perspectives for targeting senescence in osteoarthritis

Jérémy Boulestreau , Marie Maumus , Christian Jorgensen , Danièle Noël
Advanced Drug Delivery Reviews, 2021, 175, pp.113836. ⟨10.1016/j.addr.2021.113836⟩
Journal articles hal-03649447v1
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Editorial: Key Players in Systemic Sclerosis: The Immune System and Beyond

Philippe Guilpain , Danièle Noël , Jérôme Avouac
Frontiers in Immunology, 2021, 12, pp.770419. ⟨10.3389/fimmu.2021.770419⟩
Journal articles hal-03647291v1
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Cancer incidence in primary Sjögren's syndrome: Data from the French hospitalization database

Radjiv Goulabchand , Nicolas Malafaye , William Jacot , Philine Witkowski Durand Viel , Jacques Morel
Autoimmunity Reviews, 2021, 20 (12), pp.102987. ⟨10.1016/j.autrev.2021.102987⟩
Journal articles hal-03622565v1
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Mesenchymal Stromal Cell-Derived Extracellular Vesicles Regulate the Mitochondrial Metabolism via Transfer of miRNAs

Claire Loussouarn , Yves-Marie Pers , Claire Bony , Christian Jorgensen , Danièle Noël
Frontiers in Immunology, 2021, 12, pp.623973. ⟨10.3389/fimmu.2021.623973⟩
Journal articles hal-03662528v1
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Pyrroline-5-Carboxylate Reductase 1 Directs the Cartilage Protective and Regenerative Potential of Murphy Roths Large Mouse Mesenchymal Stem Cells

Gautier Tejedor , Rafael Contreras-Lopez , Audrey Barthelaix , Maxime Ruiz , Danièle Noël
Frontiers in Cell and Developmental Biology, 2021, 9, pp.604756. ⟨10.3389/fcell.2021.604756⟩
Journal articles hal-03653004v1
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Validation of a new fluidic device for mechanical stimulation and characterization of microspheres: A first step towards cartilage characterization

Noémie Petitjean , Gilles Dusfour , Patrick Cañadas , Marie Maumus , Patrice Valorge
Materials Science and Engineering: C, 2021, 121, pp.111800. ⟨10.1016/j.msec.2020.111800⟩
Journal articles hal-03094520v1
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Development of extracellular vesicle-based medicinal products: A position paper of the group “Extracellular Vesicle translatiOn to clinicaL perspectiVEs – EVOLVE France”

Amanda K.A. Silva , Marie Morille , Max Piffoux , Surendar Arumugam , Phlippe Mauduit
Advanced Drug Delivery Reviews, 2021, 179, pp.114001. ⟨10.1016/j.addr.2021.114001⟩
Journal articles hal-03412034v1
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Extracellular Vesicles Are More Potent Than Adipose Mesenchymal Stromal Cells to Exert an Anti-Fibrotic Effect in an In Vitro Model of Systemic Sclerosis

Pauline Rozier , Marie Maumus , Claire Bony , Alexandre Thibault Jacques Maria , Florence Sabatier
International Journal of Molecular Sciences, 2021, 22 (13), pp.6837. ⟨10.3390/ijms22136837⟩
Journal articles hal-03648928v1
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Establishment of a collection of human pluripotent stem cell lines (iPSC) from mesenchymal stem cells (MSC) from three healthy elderly donors

Lydiane Pichard , Jean-Marc Brondello , Fabienne Becker , Romain Desprat , Frédéric de Ceuninck
Stem Cell Research, 2021, 53, pp.102297. ⟨10.1016/j.scr.2021.102297⟩
Journal articles hal-03664523v1
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Neuromedin B promotes chondrocyte differentiation of mesenchymal stromal cells via calcineurin and calcium signaling

Marie Maumus , Guillaume Fonteneau , Maxime Ruiz , Said Assou , Hassan Boukhaddaoui
Cell & Bioscience, 2021, 11 (1), pp.183. ⟨10.1186/s13578-021-00695-1⟩
Journal articles hal-03640035v1
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Biobased pH-responsive and self-healing hydrogels prepared from O-carboxymethyl chitosan and a 3-dimensional dynamer as cartilage engineering scaffold

Rui Yu , Yan Zhang , Mihail Barboiu , Marie Maumus , Danièle Noël
Carbohydrate Polymers, 2020, 244, pp.116471. ⟨10.1016/j.carbpol.2020.116471⟩
Journal articles hal-02961328v1
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Characterization of immortalized human islet stromal cells reveals a MSC-like profile with pancreatic features

Orianne Villard , Mathieu Armanet , Guilhem Couderc , Claire Bony , Jerome Moreaux
Current Stem Cell Research & Therapy, 2020, 11, pp.158. ⟨10.1186/s13287-020-01649-z⟩
Journal articles hal-02961501v1
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Inorganic Sol−Gel Polymerization for Hydrogel Bioprinting

Titouan Montheil , Marie Maumus , Laurine Valot , Aurélien Lebrun , Jean Martínez
ACS Omega, 2020, 5 (6), pp.2640-2647. ⟨10.1021/acsomega.9b03100⟩
Journal articles hal-02513894v1
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TGFBI secreted by mesenchymal stromal cells ameliorates osteoarthritis and is detected in extracellular vesicles

Maxime Ruiz , Karine Toupet , Marie Maumus , Pauline Rozier , Christian Jorgensen
Biomaterials, 2020, 226, pp.119544. ⟨10.1016/j.biomaterials.2019.119544⟩
Journal articles hal-02329519v1
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Mesenchymal stem cells-derived cartilage micropellets: A relevant in vitro model for biomechanical and mechanobiological studies of cartilage growth

Gilles Dusfour , M. Maumus , Patrick Cañadas , Dominique Ambard , C. Jorgensen
Materials Science and Engineering: C, 2020, 112, pp.110808. ⟨10.1016/j.msec.2020.110808⟩
Journal articles hal-02961442v1
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Mesenchymal Stem Cell-Derived Extracellular Vesicles: Opportunities and Challenges for Clinical Translation

Marie Maumus , Pauline Rozier , Jérémy Boulestreau , Christian Jorgensen , Danièle Noël
Frontiers in Bioengineering and Biotechnology, 2020, 8, pp.997. ⟨10.3389/fbioe.2020.00997⟩
Journal articles hal-02961423v1
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Generation of human pluripotent stem cell lines (iPSCs) from mesenchymal stem cells (MSCs) from three elderly patients with osteoarthritis

Lydiane Pichard , Jean-Marc Brondello , Fabienne Becker , Romain Desprat , Frédéric de Ceuninck
Stem Cell Research, 2020, 44, pp.101721. ⟨10.1016/j.scr.2020.101721⟩
Journal articles hal-02961555v1
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Identification of TGFβ signatures in six murine models mimicking different osteoarthritis clinical phenotypes

Marie Maumus , Danièle Noël , Hang Korng Ea , David Moulin , Maxime Ruiz
Osteoarthritis and Cartilage, 2020, 28 (10), pp.1373-1384. ⟨10.1016/j.joca.2020.06.008⟩
Journal articles hal-02899374v1
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Mesenchymal Stem Cell Derived Extracellular Vesicles in Aging

Jérémy Boulestreau , Marie Maumus , Pauline Rozier , Christian Jorgensen , Danièle Noël
Frontiers in Cell and Developmental Biology, 2020, 8, pp.107. ⟨10.3389/fcell.2020.00107⟩
Journal articles hal-02961436v1
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Time-dependent LPS exposure commands MSC immunoplasticity through TLR4 activation leading to opposite therapeutic outcome in EAE

Mónica Kurte , Ana María Vega-Letter , Patricia Luz-Crawford , Farida Djouad , Danièle Noël
Current Stem Cell Research & Therapy, 2020, 11, pp.416. ⟨10.1186/s13287-020-01840-2⟩
Journal articles hal-02961469v1
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Biocompatible Glycine‐Assisted Catalysis of the Sol‐Gel Process: Development of Cell‐Embedded Hydrogels

Laurine Valot , Marie Maumus , Titouan Montheil , Jean Martinez , Daniele Noel
ChemPlusChem, 2019, 84 (11), pp.1720-1729. ⟨10.1002/cplu.201900509⟩
Journal articles hal-02392144v1
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Intriguing Relationships Between Cancer and Systemic Sclerosis: Role of the Immune System and Other Contributors

Alexandre Thibault Jacques Maria , Léo Partouche , Radjiv Goulabchand , Sophie Rivière , Pauline Rozier
Frontiers in Immunology, 2019, 9, pp.3112. ⟨10.3389/fimmu.2018.03112⟩
Journal articles hal-02307243v1

Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development

Olivier Malaise , Yassin Tachikart , Michael Constantinides , Marcus Mumme , Rosanna Ferreira-Lopez
Aging, 2019, 11 (20), pp.9128-9146. ⟨10.18632/aging.102379⟩
Journal articles hal-02551968v1
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iNOS Activity Is Required for the Therapeutic Effect of Mesenchymal Stem Cells in Experimental Systemic Sclerosis

Alexandre Maria , Pauline Rozier , Guillaume Fonteneau , Thibault Sutra , Marie Maumus
Frontiers in Immunology, 2018, 9, pp.3056. ⟨10.3389/fimmu.2018.03056⟩
Journal articles hal-01976916v1
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Mesenchymal stem cells and regenerative medicine

Marie Maumus , Yves-Marie Pers , Maxime Ruiz , Christian Jorgensen , Danièle Noël
Médecine/Sciences, 2018, 34 (12), pp.1092-1099. ⟨10.1051/medsci/2018294⟩
Journal articles hal-02307298v1
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Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis

Stella Cosenza , Karine Toupet , Marie Maumus , Patricia Luz-Crawford , Olivier Blanc-Brude
Theranostics, 2018, 8 (5), pp.1399 - 1410. ⟨10.7150/thno.21072⟩
Journal articles hal-01833435v1
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Fibrosis Development in HOCl-Induced Systemic Sclerosis: A Multistage Process Hampered by Mesenchymal Stem Cells

Alexandre Maria , Karine Toupet , Marie Maumus , Pauline Rozier , Marie-Catherine Vozenin
Frontiers in Immunology, 2018, 9, pp.2571. ⟨10.3389/fimmu.2018.02571⟩
Journal articles hal-02309956v1
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Secreted α-Klotho maintains cartilage tissue homeostasis by repressing NOS2 and ZIP8-MMP13 catabolic axis.

Paul Chuchana , Anne-Laure Mausset-Bonnefont , Marc Mathieu , Francisco Espinoza , Marisa Teigell
Aging, 2018, 10 (6), pp.1442-1453. ⟨10.18632/aging.101481⟩
Journal articles hal-01834060v1

Contribution of microRNAs to the immunosuppressive function of mesenchymal stem cells

Yves-Marie Pers , Marie Maumus , Claire Bony , Christian Jorgensen , Danièle Noël
Biochimie, 2018, 155, pp.109-118. ⟨10.1016/j.biochi.2018.07.001⟩
Journal articles hal-01877967v1
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Mesenchymal Stem Cells in Systemic Sclerosis: Allogenic or Autologous Approaches for Therapeutic Use?

Pauline Rozier , Alexandre Maria , Radjiv Goulabchand , Christian Jorgensen , Philippe Guilpain
Frontiers in Immunology, 2018, 9, pp.2938. ⟨10.3389/fimmu.2018.02938⟩
Journal articles hal-02304369v1
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Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis

Stella Cosenza , Maxime Ruiz , Karine Toupet , Christian Jorgensen , Danièle Noël
Scientific Reports, 2017, 7, pp.16214. ⟨10.1038/s41598-017-15376-8⟩
Journal articles hal-01740887v1
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Pathogenic or Therapeutic Extracellular Vesicles in Rheumatic Diseases: Role of Mesenchymal Stem Cell-Derived Vesicles

Stella Cosenza , Maxime Ruiz , Marie Maumus , Christian Jorgensen , Danièle Noël
International Journal of Molecular Sciences, 2017, 18 (4), pp.889. ⟨10.3390/ijms18040889⟩
Journal articles hal-01623928v1
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Adipose-Derived Mesenchymal Stem Cells in Autoimmune Disorders: State of the Art and Perspectives for Systemic Sclerosis

Alexandre At Maria , Maumus Marie , Alain Le Quellec , Christian Jorgensen , Daniele Noël
Clinical Reviews in Allergy and Immunology, 2017, 52 (2), pp.234-259. ⟨10.1007/s12016-016-8552-9⟩
Journal articles inserm-01342436v1
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Thrombospondin-1 Partly Mediates the Cartilage Protective Effect of Adipose-Derived Mesenchymal Stem Cells in Osteoarthritis

Marie Maumus , Cristina Manferdini , Karine Toupet , Paul Chuchana , Louis Casteilla
Frontiers in Immunology, 2017, 8, pp.1638. ⟨10.3389/fimmu.2017.01638⟩
Journal articles hal-01739813v1
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Serum-Mediated Oxidative Stress from Systemic Sclerosis Patients Affects Mesenchymal Stem Cell Function

Guillaume Fonteneau , Claire Bony , Radjiv Goulabchand , Alexandre T. J. Maria , Alain Le Quellec
Frontiers in Immunology, 2017, 8 (7), pp.988. ⟨10.3389/fimmu.2017.00988⟩
Journal articles hal-01623926v1
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Modular bioink for 3D printing of biocompatible hydrogels: sol-​gel polymerization of hybrid peptides and polymers

Cécile Echalier , R. Levato , M.A. Mateos-Timoneda , O. Castano , S. Dejean
RSC Advances, 2017, 7 (20), pp.12231-12235. ⟨10.1039/c6ra28540f⟩
Journal articles hal-01476346v1

Tripartite polyionic complex (PIC) micelles as non-viral vectors for mesenchymal stem cell siRNA transfection

Sophie Raisin , Marie Morille , Claire Bony , Danièle Noël , Jean-Marie Devoisselle
Biomaterials Science, 2017, 5 (9), pp.1910 - 1921. ⟨10.1039/c7bm00384f⟩
Journal articles hal-01834627v1

Mesenchymal stem cells seeded on a human amniotic membrane improve liver regeneration and mouse survival after extended hepatectomy

Aure Despeyroux , Cédric Duret , Claire Gondeau , Esther Perez-Gracia , Lisa Chuttoo
Journal of Tissue Engineering and Regenerative Medicine, 2017, ⟨10.1002/term.2607⟩
Journal articles hal-01743116v1
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Sol-gel synthesis of collagen-inspired peptide hydrogel

Cécile Echalier , Said Jebors , Guillaume Laconde , Luc Brunel , Pascal Verdié
Materials Today, 2017, 20 (2), pp.59-66. ⟨10.1016/j.mattod.2017.02.001⟩
Journal articles hal-01516237v1

Erratum: Deregulation and therapeutic potential of microRNAs in arthritic diseases

Rita Vicente , Danièle Noël , Yves-Marie Pers , Florence Apparailly , Christian Jorgensen
Nature Reviews Rheumatology, 2016, 12 (8), pp.496 - 496. ⟨10.1038/nrrheum.2016.119⟩
Journal articles hal-01844606v1

PLGA-based microcarriers induce mesenchymal stem cell chondrogenesis and stimulate cartilage repair in osteoarthritis

Marie Morille , Karine Toupet , Claudia Montero-Menei , Christian Jorgensen , Danièle Noël
Biomaterials, 2016, 88, pp.60 - 69. ⟨10.1016/j.biomaterials.2016.02.022⟩
Journal articles hal-01834277v1

Reply

Alexandre Maria , Christian Jorgensen , Alain Le Quellec , Danièle Noël , Philippe Guilpain
Arthritis & rheumatology, 2016, 68 (9), pp.2348 - 2350. ⟨10.1002/art.39756⟩
Journal articles hal-01834300v1
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Utility of a Mouse Model of Osteoarthritis to Demonstrate Cartilage Protection by IFNγ-Primed Equine Mesenchymal Stem Cells

Marie Maumus , Gautier Roussignol , Karine Toupet , Geraldine Penarier , Isabelle Bentz
Frontiers in Immunology, 2016, 7, pp.392. ⟨10.3389/fimmu.2016.00392⟩
Journal articles hal-01818646v1
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Comparison between Stromal Vascular Fraction and Adipose Mesenchymal Stem Cells in Remodeling Hypertrophic Scars

Sophie Domergue , Claire Bony , Marie Maumus , Karine Toupet , Eric Frouin
PLoS ONE, 2016, 11 (5), ⟨10.1371/journal.pone.0156161⟩
Journal articles hal-01834377v1

Deregulation and therapeutic potential of microRNAs in arthritic diseases

Rita Vicente , Danièle Noël , Yves-Marie Pers , Florence Apparailly , Christian Jorgensen
Nature Reviews Rheumatology, 2016, 12 (4), pp.211 - 220. ⟨10.1038/nrrheum.2015.162⟩
Journal articles hal-01834238v1

Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl-Induced Systemic Sclerosis

Alexandre Maria , Karine Toupet , Claire Bony , Nelly Pirot , Marie-Catherine Vozenin
Arthritis & rheumatology, 2016, 68 (4), pp.1013 - 1025. ⟨10.1002/art.39477⟩
Journal articles hal-01834297v1

The immunosuppressive signature of menstrual blood mesenchymal stem cells entails opposite effects on experimental arthritis and graft versus host diseases

Patricia Luz-Crawford , María Torres , Danièle Noël , Ainoa Fernandez , Karine Toupet
STEM CELLS, 2016, 34 (2), pp.456 - 469. ⟨10.1002/stem.2244⟩
Journal articles hal-01834145v1

Human adipose mesenchymal stem cells as potent anti-fibrosis therapy for systemic sclerosis

Alexandre T.J. Maria , Karine Toupet , Marie Maumus , Guillaume Fonteneau , Alain Le Quellec
Journal of Autoimmunity, 2016, 70, pp.31 - 39. ⟨10.1016/j.jaut.2016.03.013⟩
Journal articles hal-01834289v1
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Therapeutic application of mesenchymal stem cells in osteoarthritis

Maxime Ruiz , Stella Cosenza , Marie Maumus , Christian Jorgensen , Danièle Noël
Expert Opinion on Biological Therapy, 2016, 16 (1), pp.33-42. ⟨10.1517/14712598.2016.1093108⟩
Journal articles hal-01834251v1

Inhibition of Osteoarthritis by Adipose-Derived Stromal Cells Overexpressing Fra-1 in Mice

Kay Schwabe , Mireia Garcia , Kenia Ubieta , Nicole Hannemann , Bettina Herbort
Arthritis & rheumatology, 2016, 68 (1), pp.138 - 151. ⟨10.1002/art.39425⟩
Journal articles hal-01834247v1

PPARβ/δ directs the therapeutic potential of mesenchymal stem cells in arthritis

C Luz-Crawford , N Ipseiz , G Espinosa-Carrasco , C Caicedo , G Tejedor
Annals of the Rheumatic Diseases, 2016, 75 (12), pp.2166 - 2174. ⟨10.1136/annrheumdis-2015-208696⟩
Journal articles hal-01834105v1

Mesenchymal Stem Cell-Derived Interleukin 1 Receptor Antagonist Promotes Macrophage Polarization and Inhibits B Cell Differentiation

Patricia Luz-Crawford , Farida Djouad , Karine Toupet , Claire Bony , Marcella Franquesa
STEM CELLS, 2016, 34 (2), pp.483 - 492. ⟨10.1002/stem.2254⟩
Journal articles hal-01834077v1
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Adipose Mesenchymal Stem Cells Isolated after Manual or Water-jet-Assisted Liposuction Display Similar Properties

Claire Bony , Maïlys Cren , Sophie Domergue , Karine Toupet , Christian Jorgensen
Frontiers in Immunology, 2016, 6, ⟨10.3389/fimmu.2015.00655⟩
Journal articles hal-01834394v1
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Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial

Yves-Marie Pers , Lars Rackwitz , Rosanna Ferreira , Oliver Pullig , Christophe Delfour
Stem Cells Translational Medicine, 2016, 5 (7), pp.847 - 856. ⟨10.5966/sctm.2015-0245⟩
Journal articles hal-01834263v1

Lack of anti-inflammatory and anti-catabolic effects on basal inflamed osteoarthritic chondrocytes or synoviocytes by adipose stem cell-conditioned medium

C. Manferdini , M. Maumus , E. Gabusi , F. Paolella , F. Grassi
Osteoarthritis and Cartilage, 2015, 23 (11), pp.2045 - 2057. ⟨10.1016/j.joca.2015.03.025⟩
Journal articles hal-01834501v1

Advances in Research in Animal Models of Burn-Related Hypertrophic Scarring

Sophie Domergue , Christian Jorgensen , Danièle Noël
Journal of Burn Care and Research, 2015, 36 (5), pp.e259 - e266. ⟨10.1097/bcr.0000000000000167⟩
Journal articles hal-01834588v1

Mesenchymal stem cells for the management of inflammation in osteoarthritis: state of the art and perspectives

M. Pers , M. Ruiz , Danièle Noël , C. Jorgensen
Osteoarthritis and Cartilage, 2015, 23 (11), pp.2027 - 2035. ⟨10.1016/j.joca.2015.07.004⟩
Journal articles hal-01834450v1
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Survival and Biodistribution of Xenogenic Adipose Mesenchymal Stem Cells Is Not Affected by the Degree of Inflammation in Arthritis

Karine Toupet , Marie Maumus , Patricia Luz-Crawford , Eleuterio Lombardo , Juan Lopez-Belmonte
PLoS ONE, 2015, 10 (1), ⟨10.1371/journal.pone.0114962⟩
Journal articles hal-01834412v1

Glucocorticoid-Induced Leucine Zipper Governs the Therapeutic Potential of Mesenchymal Stem Cells by Inducing a Switch From Pathogenic to Regulatory Th17 Cells in a Mouse Model of Collagen-Induced Arthritis

P. Luz-Crawford , G. Tejedor , Anne-Laure Mausset-Bonnefont , E. Beaulieu , F. Morand
Arthritis & rheumatology, 2015, 67 (6), pp.1514 - 1524. ⟨10.1002/art.39069⟩
Journal articles hal-01834130v1

In vitro and in vivo characterization of antibacterial activity and biocompatibility: A study on silver-containing phosphonate monolayers on titanium

Carmen-Mihaela Tilmaciu , Marc Mathieu , Jean-Philippe Lavigne , Karine Toupet , Gilles Guerrero
Acta Biomaterialia, 2015, 15, pp.266-277. ⟨10.1016/j.actbio.2014.12.020⟩
Journal articles hal-01122929v1
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PLA-poloxamer/poloxamine copolymers for ligament tissue engineering: sound macromolecular design for degradable scaffolds and MSC differentiation

Adrien Leroy , Benjamin Nottelet , Claire Bony , Coline Pinese , Benoît Charlot
Biomaterials Science, 2015, 3 (4), pp.617-626. ⟨10.1039/c4bm00433g⟩
Journal articles hal-01369239v1

Ingénierie tissulaire du ligament : polymères dégradables et cellules souches au service de la régénération

Adrien Leroy , Benjamin Nottelet , Xavier Garric , Danièle Noël , Jean Coudane
L'Actualité Chimique, 2014, 390, pp.50-52
Journal articles hal-04416580v1

Treatment efficacy of adipose-derived stem cells in experimental osteoarthritis is driven by high synovial activation and reflected by S100A8/A9 serum levels

Schelbergen Rik F. , Stephanie van Dalen , Menno ter Huurne , Johannes Roth , Thomas Vogl
Osteoarthritis and Cartilage, 2014, 22 (8), pp.1158-1166. ⟨10.1016/j.joca.2014.05.022⟩
Journal articles hal-03137425v1
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Promyelocytic leukemia zinc-finger induction signs mesenchymal stem cell commitment: identification of a key marker for stemness maintenance?

Farida Djouad , Gautier Tejedor , Karine Toupet , Marie Maumus , Claire Bony
Stem Cell Research and Therapy, 2014, 5 (1), pp.27. ⟨10.1186/scrt416⟩
Journal articles inserm-00976578v1
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Biodegradable networks for soft tissue engineering by thiol–yne photo cross-linking of multifunctional polyesters.

Adrien Leroy , Assala Al Samad , Xavier Garric , Sylvie Hunger , Danièle Noël
RSC Advances, 2014, 4 (60), pp.32017-32023. ⟨10.1039/c4ra03665d⟩
Journal articles hal-01091330v1

FOXO3A Regulation by miRNA-29a Controls Chondrogenic Differentiation of Mesenchymal Stem Cells and Cartilage Formation

David Guérit , Jean-Marc Brondello , Paul Chuchana , Didier Philipot , Karine Toupet
Stem Cells and Development, 2014, 23 (11), pp.1195 - 1205. ⟨10.1089/scd.2013.0463⟩
Journal articles hal-01836483v1
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Involvement of Angiopoietin-like 4 in Matrix Remodeling during Chondrogenic Differentiation of Mesenchymal Stem Cells

Marc Mathieu , Mathieu Iampietro , Paul Chuchana , David Guérit , Farida Djouad
Journal of Biological Chemistry, 2014, 289 (12), pp.8402-8412. ⟨10.1074/jbc.M113.539825⟩
Journal articles hal-03116030v1
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p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodelling in osteoarthritis.

Didier Philipot , David Guérit , Daniela Platano , Paul Chuchana , Eleonora Olivotto
Arthritis Research and Therapy, 2014, 16 (1), pp.R58. ⟨10.1186/ar4494⟩
Journal articles inserm-00983071v1
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Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells.

Patricia Luz-Crawford , Monica Kurte , Javiera Bravo-Alegría , Rafael Contreras , Estefania Nova-Lamperti
Stem Cell Research and Therapy, 2013, 4 (3), pp.65. ⟨10.1186/scrt216⟩
Journal articles inserm-00836318v1
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Investigation on the properties of linear PLA-poloxamer and star PLA-poloxamine copolymers for temporary biomedical applications.

Adrien Leroy , Coline Pinese , Claire Bony , Xavier Garric , Danièle Noël
Materials Science and Engineering: C, 2013, 33 (7), pp.4133-4139. ⟨10.1016/j.msec.2013.06.001⟩
Journal articles hal-00967461v1
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Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: Role of secretome and exosomes.

Marie Maumus , Christian Jorgensen , Danièle Noël
Biochimie, 2013, epub ahead of print. ⟨10.1016/j.biochi.2013.04.017⟩
Journal articles inserm-00832507v1
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Therapeutic mesenchymal stem cells in rheumatic diseases: rationale, clinical data and perspectives

David Guérit , Marie Maumus , Florence Apparailly , Christian Jorgensen , Danièle Noël
Clinical Investigation, 2011, 1 (9), pp.1269-1277
Journal articles inserm-00644029v1
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The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts.

Virginie Vives , Mélanie Laurin , Gaelle Cres , Pauline Larrousse , Zakia Morichaud
Journal of Bone and Mineral Research, 2011, 26 (5), pp.1099-1110. ⟨10.1002/jbmr.282⟩
Journal articles hal-00533670v1
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Mesenchymal stem cell-based therapies in regenerative medicine: applications in rheumatology.

Marie Maumus , David Guérit , Karine Toupet , Christian Jorgensen , Danièle Noël
Stem Cell Research and Therapy, 2011, 2 (2), pp.14. ⟨10.1186/scrt55⟩
Journal articles inserm-00585188v1
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Isolation of mineralizing Nestin+ Nkx6.1+ vascular muscular cells from the adult human spinal cord

Daria Mamaeva , Chantal Ripoll , Claire Bony , Marisa Teigell , Florence Perrin
BMC Neuroscience, 2011, 12 (1), pp.99. ⟨10.1186/1471-2202-12-99⟩
Journal articles inserm-00637318v1

The role of pharmacologically active microcarriers releasing TGF-beta3 in cartilage formation in vivo by mesenchymal stem cells

Carine Bouffi , Olivier Thomas , Claire Bony , Alexandra Giteau , Marie-Claire Venier-Julienne
Biomaterials, 2010, 31 (25), pp.6485-6493. ⟨10.1016/j.biomaterials.2010.05.013⟩
Journal articles hal-03171848v1

Immunosuppression by mesenchymal stem cells: mechanisms and clinical applications

Soufiane Ghannam , Carine Bouffi , Farida Djouad , Christian Jorgensen , Danièle Noël
Current Stem Cell Research & Therapy, 2010, 1 (1), ⟨10.1186/scrt2⟩
Journal articles inserm-01878105v1
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Comparative proteomic analysis of human mesenchymal and embryonic stem cells: towards the definition of a mesenchymal stem cell proteomic signature

Stéphane Roche , B. Delorme , R. Oostendorp , R. Barbet , C. Caton
Proteomics, 2009, 9 (2), pp.223-232. ⟨10.1002/pmic.200800035⟩
Journal articles hal-00357170v1

Transcriptomic Analysis Identifies Foxo3A as a Novel Transcription Factor Regulating Mesenchymal Stem Cell Chrondrogenic Differentiation

Farida Djouad , Claire Bony , François Canovas , Olivia Fromigue , Thierry Rème
Cloning and Stem Cells, 2009, 11 (3), pp.407 - 416. ⟨10.1089/clo.2009.0013⟩
Journal articles inserm-01878108v1
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Cartilage tissue engineering: towards a biomaterial-assisted mesenchymal stem cell therapy.

Claire Vinatier , Carine Bouffi , Christophe Merceron , Jan Gordeladze , Jean-Marc Brondello
Current Stem Cell Research & Therapy, 2009, 4 (4), pp.318-29
Journal articles inserm-00423696v1

Antitumoral Activity and Osteogenic Potential of hATF-Expressing Mesenchymal Stem Cells In A Murine Model of Osteolytic Tumor.

Vanessa Fritz , Danièle Noël , Céline Bouquet , Paule Opolon , Romain Voide
Stem Cells / Stem Cells (Miamisburg), 2008, epub ahead of print. ⟨10.1634/stemcells.2008-0139⟩
Journal articles hal-00315969v1
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Cell specific differences between human adipose derived- and mesenchymal- stromal cells despite similar differentiation potentials.

Danièle Noël , David Caton , S. Roche , Claire Bony , Sylvain Lehmann
Experimental Cell Research, 2008, 314 (7), pp.1575-1584. ⟨10.1016/j.yexcr.2007.12.022⟩
Journal articles hal-00275173v1

Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor alpha in experimental arthritis.

Maroun Khoury , Pascale Louis-Plence , Virginie Escriou , Danièle Noël , Céline Largeau
Arthritis and Rheumatism, 2006, 54 (6), pp.1867-77. ⟨10.1002/art.21876⟩
Journal articles inserm-00193135v1

A comparative study on intra-articular versus systemic gene electrotransfer in experimental arthritis.

Maroun Khoury , Pascal Bigey , Pascale Louis-Plence , Danièle Noël , Hervé Rhinn
The Journal of Gene Medicine, 2006, 8 (8), pp.1027-36. ⟨10.1002/jgm.922⟩
Journal articles inserm-00193122v1

Functional neuronal differentiation of bone marrow-derived mesenchymal stem cells.

Philippe Tropel , Nadine Platet , Jean-Claude Platel , Danièle Noël , Mireille Albrieux
Stem cells (Dayton, Ohio), 2006, 24 (12), pp.2868-76. ⟨10.1634/stemcells.2005-0636⟩
Journal articles inserm-00390759v1
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Peroxisome proliferator-activated receptor gamma regulates E-cadherin expression and inhibits growth and invasion of prostate cancer.

Jean-Sébastien Annicotte , Irena Iankova , Stéphanie Miard , Vanessa Fritz , David A. Sarruf
Molecular and Cellular Biology, 2006, 26 (20), pp.7561-74. ⟨10.1128/MCB.00605-06⟩
Journal articles inserm-00096196v1
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Transcriptional profiles discriminate bone marrow-derived and synovium-derived mesenchymal stem cells.

Farida Djouad , Claire Bony , Thomas Häupl , Gilles Uzé , Najiba Lahlou
Arthritis Research and Therapy, 2005, 7, pp.R1304-15. ⟨10.1186/ar1827⟩
Journal articles inserm-00089978v1
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Biomechanical stimulation and characterization of cartilage micropellets enabled by a unique fluidic-based device

Noémie Petitjean , Patrick Cañadas , Christian Jorgensen , Pascale Royer , Danièle Noël
46ème congrès de la Société de Biomécanique, Oct 2021, Saint-Etienne, France
Conference papers hal-03441000v1

Stimulation mécanique et caractérisation biomécanique de micropellets de cartilage avec un dispositif fluidique dédié

Noémie Petitjean , Patrick Cañadas , Christian Jorgensen , Pascale Royer , Danièle Noël
GDR Mécanique des matériaux et fluides biologiques, Jan 2021, En ligne, France
Conference papers hal-03440814v1

Mechanical stimulation and biomechanical characterization of cartilage micropellets with a single and new custom-made device

Noémie Petitjean , Marie Maumus , Gilles Dusfour , Patrick Cañadas , Christian Jorgensen
Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Meeting 2020, May 2020, Manchester, United Kingdom
Conference papers hal-03441471v1

Mechanical stimulation and mechanobiological characterization of cartilage micropellets with a single and new custom-made device

Noémie Petitjean , Marie Maumus , Gilles Dusfour , Jade Berthelot , Emmanuel Belamie
1er congrès français de médecine régénératrice et biothérapies, Oct 2020, Montpellier, France
Conference papers hal-03440712v1
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Assessment of mesenchymental stem cell micropellet as a relevant biomechanical in vitro model devoted to the study of cartilage growth

Gilles Dusfour , Maumus Marie , Patrick Cañadas , Dominique Ambard , Christian Jorgensen
44ème Congrès de la Société de Biomécanique, Oct 2019, Poitiers, France. pp.S314-S316, ⟨10.1080/10255842.2020.1714925⟩
Conference papers hal-02315196v1
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Validation of a new technique dedicated to the mechanical characterisation of cartilage micropellets

Noémie Petitjean , Marie Maumus , Gilles Dusfour , Patrick Cañadas , Christian Jorgensen
44ème Congrès de la Société de Biomécanique, Société de Biomécanique; Université de Poitiers; CHU de Poitiers, Oct 2019, Poitiers, France. pp.S296-S298, ⟨10.1080/10255842.2020.1714919⟩
Conference papers hal-02171759v1

Sol-gel and peptides: an attractive route to unprecedented biomaterials

Gilles Subra , Laurine Valot , Manon Maurel , Cécile Echalier , Danièle Noël
35th European Peptide Symposium, Jan 2018, Dublin, Ireland. pp.28-32
Conference papers hal-02015368v1

Mesenchymal stem cells-derived micropellet is a relevant in vitro model for biomechanical modeling of cartilage growth

Gilles Dusfour , Marie Maumus , Simon Le Floc'H , Dominique Ambard , Christian Jorgensen
8th World Congress of Biomechanics, Jul 2018, Dublin, Ireland
Conference papers hal-01767884v1

Mesenchymal Stem Cells-derived cartilage micropellet: a relevant model for biomechanical and mechanobiological modelisation of cartilage growth

Marie Maumus , Gilles Dusfour , Simon Le Floc'H , Dominique Ambard , Christian Jorgensen
2018 eCM XVIII: Cartilage & Disc: Repair and Regeneration, Jun 2018, Davos, Switzerland
Conference papers hal-01768746v1

TGFb-induced Protein is Dysregulated in Osteoarthritis

M Ruiz , M. Maumus , K. Toupet , G. Fonteneau , Y.-M. Pers
World Congress of the Osteoarthritis-Research-Society-International (OARSI) on Osteoarthritis, Mar 2017, Las Vegas, NV, United States. pp.S325 - S326, ⟨10.1016/j.joca.2017.02.544⟩
Conference papers hal-01833503v1

Protective effect of thrombospondin-4 expressing mesenchymal stem cells in osteoarthritis

M. Maumus , K. Toupet , Farida Djouad , J.-P. David , C. Jorgensen
World Congress of the Osteoarthritis-Research-Society-International (OARSI) on Osteoarthritis, Mar 2016, Amsterdam, Netherlands. ⟨10.1016/j.joca.2016.01.926⟩
Conference papers hal-01834285v1

Protective effect of thrombospondin-4 expressing mesenchymal stem cells in osteoarthritis

M Maumus , K Toupet , Farida Djouad , D David , C Jorgensen
36th European Workshop for Rheumatology Research (EWRR), Feb 2016, York, United Kingdom. pp.A56.2 - A56, ⟨10.1136/annrheumdis-2016-209124.133⟩
Conference papers hal-01834281v1

Anti-fibrotic and anti-inflammatory effect of mesenchymal stem cells in murine hypochlorite-induced systemic sclerosis

A. Maria , C Bony , K. Toupet , C Jorgensen , P. Guilpain
ANNALS OF THE RHEUMATIC DISEASES, Mar 2015, London, United Kingdom. pp.A33.3 - A34, ⟨10.1136/annrheumdis-2015-207259.78⟩
Conference papers hal-01834477v1

Adipose stromal cells effects on osteoarthritic synoviocytes are dependent by macrophages

C. Manferdini , E. Gabusi , F. Paolella , A. Piacentini , S. Fleury-Cappellesso
World Congress of the Osteoarthritis-Research-Society-International (OARSI) on Osteoarthritis, Apr 2015, Seattle, United States. ⟨10.1016/j.joca.2015.02.708⟩
Conference papers hal-01834510v1

Ligament Tissue Engineering: PLA-based Linear And Star Copolymers Scaffolds To Promote The Differentiation Of Mesenchymal Stem Cells

Adrien Leroy , Coline Pinese , Claire Bony , Xavier Garric , Danièle Noël
12th International PAT Conference, Sep 2013, Berlin (Germany), Germany. pp.43-44 - S2-7, ⟨10.1002/pat.3187⟩
Conference papers hal-04387232v1
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Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathway

Patricia Luz-Crawford , Daniele Noël , Fernando Figueroa , Flavio Carrión , Christian Jorgensen
7th European Workshop on Immune-Mediated Inflammatory Diseases, Nov 2012, Noordwijk aan Zee, Netherlands. pp.P16
Conference papers inserm-00758222v1

Will Mesenchymal Stromal Cells become tools for immunomodulation in Myasthenia Gravis ?

Alexandra Bayer Wildberger , José Villegas , Julien Verdier , Mariette Giannini , Solène Maillard
12th International Congress on Autoimmunity, May 2021, Virtual Congress, Greece
Conference poster hal-03440251v1
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Moderate deformation of cartilage micropellets in a fluidic custom-made device enhances the expression of chondrocyte markers

Noémie Petitjean , Marie Maumus , Gilles Dusfour , Patrick Cañadas , Christian Jorgensen
International Society for Cell and Gene Therapy - ISCT 2021, May 2021, En ligne, United States.
Conference poster hal-03440887v1

Phenotypical and functional characterizations of conditioned Mesenchymal Stromal Cells MSC, as tools for immunomodulation in Myasthenia Gravis

Alexandra Bayer Wildberger , José Villegas , Julien Verdier , Mariette Giannini , Solène Maillard
52ème Meeting de la Société Française d'Immunologie, Nov 2019, Nantes, France
Conference poster hal-03038636v1
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Validation of a new device dedicated to the mechanical characterisation of cartilage micropellets

Noémie Petitjean , Marie Maumus , Gilles Dusfour , Patrick Cañadas , Christian Jorgensen
Journée de l'école doctorale CBS2, May 2019, Montpellier, France. , 2019
Conference poster hal-02171713v1
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Numerical modeling of cartilage growth under mechanical stresses. Mechanical and biological analysis on in vitro «micropellet» model

Marie Maumus , Gilles Dusfour , S. Lefloch , Dominique Ambard , Christian Jorgensen
5èmes journées scientifique du Labex Numev, Oct 2016, Montpellier, France. 2016
Conference poster hal-01772220v1

Pharmacologically active microcarriers enhance the survival, differentiation and regenerative potential of mesenchymal stromal cells

E Garbayo , Gaëtan Delcroix , K Curtis , A Raval , Della Morte
Autour des cellules souches, 2010, Bordeaux, France. 2010
Conference poster hal-03180806v1