Denis DAVID

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Publications

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Prucalopride, a serotonin type 4 receptor agonist, induces fast anxiolytic/antidepressant effects and concomitant changes in the gut microbiota

Sofia Cussotto , Salma R. Abdennebi , Isabelle Etting , Christine A. Denny , René Hen et al.

npj Biofilms and Microbiomes, 2026, ⟨10.1038/s41522-026-00928-6⟩

Article dans une revue hal-05497238v1

Quantitative monitoring of ketamine's impact on synaptic density using 11C-UCB-J PET imaging in the corticosterone mouse model of anxiety/depression

Cassandre Corvo , Sébastien Goutal , Indira Mendez-David , Sarah Leterrier , Fabien Caille et al.

Molecular Psychiatry, 2025, ⟨10.1038/s41380-025-03369-3⟩

Article dans une revue hal-05491087v1
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Chronic α5‐GABA‐A Receptor Potentiation Promotes Mouse Adult Hippocampal Neurogenesis

Thomas D. Prevot , Michael Marcotte , Denis J. David , Indira Mendez‐david , Md Yeunus Mian et al.

Hippocampus, 2025, 35 (4), pp.e70019. ⟨10.1002/hipo.70019⟩

Article dans une revue hal-05299983v1

Chronic, combinatorial targeting of NMDARs and 5-HT4Rs exerts extended behavioral effects against stress-induced perseverative behavior and hyponeophagia

Briana K Chen , Alicia Whye , Louise C Matthews , Taylor Moniz , Indira Mendez-David et al.

Neuropsychopharmacology, 2025, ⟨10.1038/s41386-025-02107-1⟩

Article dans une revue hal-05059155v1

Plasma kynurenine pathway metabolite levels increase in depressed patients after antidepressant treatment

Romain Colle , Kenneth Chappell , Khalil El Asmar , Bruno Fève , Philippe Chanson et al.

Brain, Behavior, and Immunity, 2025, 129, pp.92-99. ⟨10.1016/j.bbi.2025.05.025⟩

Article dans une revue hal-05099071v1

Synaptic Vesicle 2A (SV2A) Positron Emission Tomography (PET) Imaging as a Marker of Therapeutic Response in a Mouse Model of Depression

Cassandre Corvo , Indira Mendez-David , Sébastien Goutal , Wadad Saba , Michel Bottlaender et al.

ACS Pharmacology & Translational Science, 2025, 8 (2), pp.339-345. ⟨10.1021/acsptsci.4c00621⟩

Article dans une revue hal-05034545v1
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Psilocybin as Transformative Fast‐Acting Antidepressant : Pharmacological Properties and Molecular Mechanisms

Makiath Adebo , Mathilda Bonnet , Ons Laouej , Celine Defaix , Josephine C. Mcgowan et al.

Fundamental & Clinical Pharmacology, 2025, 39 (4), pp.e70038. ⟨10.1111/fcp.70038⟩

Article dans une revue (article de synthèse) hal-05237520v1

Intrahippocampal injection of a selective blocker of NMDA receptors containing the GluN2B subunit, Ro25-6981, increases glutamate neurotransmission and induces antidepressant-like effects

Julie Doan , Céline Defaix , I. Mendez-David , Alain Michel Gardier , Romain Colle et al.

Fundamental & Clinical Pharmacology, 2023, 37 (6), pp.1119-1128. ⟨10.1111/fcp.12917⟩

Article dans une revue hal-04334562v1

Metabolomic profiles of 38 acylcarnitines in major depressive episodes before and after treatment

Abd El Kader Ait Tayeb , Romain Colle , Kenneth Chappell , Khalil El-Asmar , Cécile Acquaviva-Bourdain et al.

Psychological Medicine, 2023, pp.1-10. ⟨10.1017/S003329172300140X⟩

Article dans une revue hal-04337621v1

Intranasal (R, S)-ketamine delivery induces sustained antidepressant effects associated with changes in cortical balance of excitatory/inhibitory synaptic activity

Thi Mai Loan Nguyen , Céline Defaix , I. Mendez-David , Laurent Tritschler , Isabelle Etting et al.

Neuropharmacology, 2023, 225, ⟨10.1016/j.neuropharm.2022.109357⟩

Article dans une revue hal-04068678v1
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A complex relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin

I. Mendez-David , Denis J. David , Claudine Deloménie , Laurent Tritchler , Jean Martin Beaulieu et al.

Hippocampus, 2023, 33 (10), pp.1075-1093. ⟨10.1002/hipo.23568⟩

Article dans une revue hal-04271280v1
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The GG genotype of the serotonin 4 receptor genetic polymorphism, rs1345697, is associated with lower remission rates after antidepressant treatment: Findings from the METADAP cohort

Vianney Poinsignon , Romain Colle , Khalil El Asmar , Indira Mendez-David , Denis David et al.

Journal of Affective Disorders, 2022, 299 (S1), pp.335-343. ⟨10.1016/j.jad.2021.12.012⟩

Article dans une revue hal-04020973v1

Plasma acetyl- l -carnitine and l -carnitine in major depressive episodes: a case–control study before and after treatment

Abd El Kader Ait Tayeb , Romain Colle , Khalil El-Asmar , Kenneth Chappell , Cécile Acquaviva-Bourdain et al.

Psychological Medicine, 2021, 10 (6), pp.1-10. ⟨10.1017/S003329172100413X⟩

Article dans une revue hal-04021012v1

The olfactory deficits of depressed patients are restored after remission with venlafaxine treatment

Romain Colle , Khalil El Asmar , Céline Verstuyft , Pierre-Marie Lledo , Françoise Lazarini et al.

Psychological Medicine, 2021, pp.1-9. ⟨10.1017/S0033291720003918⟩

Article dans une revue pasteur-03242612v1
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Blood microbiota and metabolomic signature of major depression before and after antidepressant treatment: a prospective case–control study

Dragos Ciocan , Anne-Marie Cassard , Laurent Becquemont , Céline Verstuyft , Cosmin Sebastian Voican et al.

Journal of Psychiatry and Neuroscience, 2021, 46 (3), pp.E358-E368. ⟨10.1503/jpn.200159⟩

Article dans une revue hal-04020991v2
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Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin

Fabienne Agasse , Indira Mendez-David , Wilhelm Christaller , Rémi Carpentier , Barbara Y. Braz et al.

Cell Reports, 2020, 32, pp.107865 -. ⟨10.1016/j.celrep.2020.107865⟩

Article dans une revue hal-03491369v1
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Rapid Anxiolytic Effects of RS67333, a Serotonin Type 4 Receptor Agonist, and Diazepam, a Benzodiazepine, Are Mediated by Projections From the Prefrontal Cortex to the Dorsal Raphe Nucleus

Charlène Faye , René Hen , Bruno P. Guiard , Christine A. Denny , Alain M. Gardier et al.

Biological Psychiatry, 2020, 87, pp.514 - 525. ⟨10.1016/j.biopsych.2019.08.009⟩

Article dans une revue hal-03489347v1

Peripheral tryptophan, serotonin, kynurenine, and their metabolites in major depression: A case–control study

Romain Colle , Perrine Masson , Céline Verstuyft , Bruno Fève , Erwan Werner et al.

Psychiatry and Clinical Neurosciences, 2020, 74 (2), pp.112-117. ⟨10.1111/pcn.12944⟩

Article dans une revue hal-04021047v1

The association of β-arrestin2 polymorphisms with response to antidepressant treatment in depressed patients

Anne-Cécile Petit , Khalil El Asmar , Denis David , Alain Gardier , Laurent Becquemont et al.

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2018, 81, pp.74-79. ⟨10.1016/j.pnpbp.2017.10.006⟩

Article dans une revue hal-04006827v1
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Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington’s disease models

Hongyu Zhang , Chunlei Zhang , Jean Vincent , Diana Zala , Caroline Benstaali et al.

Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-06675-3⟩

Article dans une revue hal-02325352v1

Photoelectron Energy Loss in Al(002) Revisited: Retrieval of the Single Plasmon Loss Energy Distribution by a Fourier Transform Method

Christian Godet , Victor Mancir da Silva Santana , Denis David , Jailton Souza de Almeida

Brazilian Journal of Physics, 2018, 48 (3), pp.215-226. ⟨10.1007/s13538-018-0566-8⟩

Article dans une revue hal-01778088v1
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Derivation of Hamaker Dispersion Energy of Amorphous Carbon Surfaces in Contact with Liquids Using Photoelectron Energy-Loss Spectra

Christian Godet , Denis David

Brazilian Journal of Physics, 2017, 47 (6), pp.594 - 605. ⟨10.1007/s13538-017-0521-0⟩

Article dans une revue hal-01655081v1

Plasma BDNF Level in Major Depression: Biomarker of the Val66Met BDNF Polymorphism and of the Clinical Course in Met Carrier Patients

Romain Colle , Séverine Trabado , Denis David , Sylvie Brailly-Tabard , Patrick Hardy et al.

Neuropsychobiology, 2017, 75 (1), pp.39-45. ⟨10.1159/000478862⟩

Article dans une revue hal-04021201v1

No impact of eight NTRK2 genetic polymorphisms on 6-month antidepressant efficacy in depressed patients

Eric Deflesselle , Céline Verstuyft , Anne-Cécile Petit , Patrick Hardy , Denis David et al.

Pharmacogenomics, 2017, 18 (4), pp.349-357. ⟨10.2217/pgs-2016-0165⟩

Article dans une revue hal-04021208v1

The Catechol-O-methyltransferase Val(108/158)Met Genetic Polymorphism cannot be Recommended as a Biomarker for the Prediction of Venlafaxine Efficacy in Patients Treated in Psychiatric Settings

Adela Taranu , Khalil El Asmar , Romain Colle , Florian Ferreri , Mircea Polosan et al.

Basic and Clinical Pharmacology and Toxicology, 2017, 121 (5), pp.435 - 441. ⟨10.1111/bcpt.12827⟩

Article dans une revue hal-01676317v1
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Derivation of dielectric function and inelastic mean free path from photoelectron energy-loss spectra of amorphous carbon surfaces

Denis David , Christian Godet

Applied Surface Science, 2016, 387, pp.1125--1139. ⟨10.1016/j.apsusc.2016.06.044⟩

Article dans une revue hal-01372807v1

Translational research on cognitive and behavioural disorders in neurological and psychiatric diseases

Jean-Christophe Corvol , Sylvia Goni , Régis Bordet , Carole Azuar , Olivier Blin et al.

Thérapie, 2016, 71 (1), pp.15-26. ⟨10.1016/j.therap.2016.01.001⟩

Article dans une revue hal-03623890v1

Blockade of the high-affinity noradrenaline transporter (NET) by the selective 5-HT reuptake inhibitor escitalopram: an in vivo microdialysis study in mice

Hai T. Nguyen , Bruno P. Guiard , Alexandre Bacq , Denis J. David , Indira David et al.

British Journal of Pharmacology, 2013, 168 (1), pp.103-116. ⟨10.1111/j.1476-5381.2012.01850.x⟩

Article dans une revue hal-01542328v1
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Derivation of the near-surface dielectric function of amorphous silicon from photoelectron loss spectra

Denis David , Christian Godet , Hussein Sabbah , Soraya Ababou-Girard , Francine Solal et al.

Journal of Non-Crystalline Solids, 2012, 358 (17), pp.2019-2022. ⟨10.1016/j.jnoncrysol.2012.01.026⟩

Article dans une revue hal-00673857v1

Bulk and surface plasmon excitations in amorphous carbon measured by core-level photoelectron spectroscopy

Christian Godet , Denis David , Hussein Sabbah , Soraya Ababou-Girard , Francine Solal

Applied Surface Science, 2009, 255 (13-14), pp.6598-6606. ⟨10.1016/J.APSUSC.2009.02.050⟩

Article dans une revue hal-00663692v1