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Didier Menard


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Ring-stage growth arrest: Metabolic basis of artemisinin tolerance in Plasmodium falciparum

Xinyu Yu , Changhong Wang , Yuemeng Zhao , Jianxia Tang , Meng Zhu
iScience, 2023, 26 (1), pp.105725. ⟨10.1016/j.isci.2022.105725⟩
Journal articles hal-04144970v1
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Ex vivo RSA and pfkelch13 targeted-amplicon deep sequencing reveal parasites susceptibility to artemisinin in Senegal, 2017

Mamadou Samb Yade , Baba Dièye , Romain Coppée , Aminata Mbaye , Mamadou Alpha Diallo
Malaria Journal, 2023, 22 (1), pp.167. ⟨10.1186/s12936-023-04588-1⟩
Journal articles hal-04144948v1
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Differential transmissibility to Anopheles arabiensis of Plasmodium vivax gametocytes in patients with diverse Duffy blood group genotypes

Andargie Abate , Jifar Hassen , Laurent Dembele , Didier Menard , Lemu Golassa
Malaria Journal, 2023, 22 (1), pp.136. ⟨10.1186/s12936-023-04570-x⟩
Journal articles hal-04144962v1
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Modified Plasmodium falciparum Ring-Stage Survival Assay with ML10 Kinase Inhibitor

Lucien Platon , David Baker , Didier Ménard
Antimicrobial Agents and Chemotherapy, 2023, 67 (5), ⟨10.1128/aac.00017-23⟩
Journal articles hal-04144955v1
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Artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular markers

Victor S Koko , Marian Warsame , Benjamin Vonhm , Moses K Jeuronlon , Didier Menard
Malaria Journal, 2022, 21, pp.134. ⟨10.1186/s12936-022-04140-7⟩
Journal articles hal-03788869v1
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Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target

Matthias Paulus Wagner , Pauline Formaglio , Olivier Gorgette , Jerzy Michal Dziekan , Christèle Huon
Cell Reports, 2022, 39 (11), pp.110923. ⟨10.1016/j.celrep.2022.110923⟩
Journal articles hal-03790129v1
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Genetic Variants of Glucose-6-Phosphate Dehydrogenase and Their Associated Enzyme Activity: A Systematic Review and Meta-Analysis.

Daniel A Pfeffer , Ari Winasti Satyagraha , Arkasha Sadhewa , Mohammad Shafiul Alam , Germana Bancone
Pathogens, 2022, 11 (9), pp.1045. ⟨10.3390/pathogens11091045⟩
Journal articles hal-03788705v1
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Pfkelch13 Plasmodium falciparum Mutations in Huambo, Angola.

Ana Beatriz Batista Rodrigues , Rebecca de Abreu-Fernandes , Zoraima Neto , Domingos Jandondo , Natália Ketrin Almeida-De-Oliveira
Pathogens, 2022, 11 (5), pp.554. ⟨10.3390/pathogens11050554⟩
Journal articles hal-03788699v1
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Repeatability and reproducibility of a handheld quantitative G6PD diagnostic.

Benedikt Ley , Ari Winasti Satyagraha , Mohammad Golam Kibria , Jillian Armstrong , Germana Bancone
PLoS Neglected Tropical Diseases, 2022, 16 (2), pp.e0010174. ⟨10.1371/journal.pntd.0010174⟩
Journal articles hal-03790033v1
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Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria

Walter Robert Taylor , Richard M Hoglund , Pimnara Peerawaranun , Thuy Nhien Nguyen , Tran Tinh Hien
Malaria Journal, 2021, 20 (1), pp.366. ⟨10.1186/s12936-021-03886-w⟩
Journal articles inserm-03451567v1
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Anti-malarial efficacy and resistance monitoring of artemether-lumefantrine and dihydroartemisinin-piperaquine shows inadequate efficacy in children in Burkina Faso, 2017–2018

Adama Gansané , Leah F. Moriarty , Didier Menard , Isidore Yerbanga , Esperance Ouedraogo
Malaria Journal, 2021, 20 (1), pp.48. ⟨10.1186/s12936-021-03585-6⟩
Journal articles pasteur-03274271v1
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Hyperendemicity of cysticercosis in Madagascar: Novel insights from school children population-based antigen prevalence study

Jean-François Carod , Frédéric Mauny , Anne Laure Parmentier , Maxime Desmarets , Mahenintsoa Rakotondrazaka
PLoS ONE, 2021, 16 (10), pp.e0258035. ⟨10.1371/journal.pone.0258035⟩
Journal articles hal-03788894v1
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Compensating P. falciparum artemisinin resistance

Lucien Platon , Jun Cao , Didier Menard
Cell Host & Microbe, 2021, 29 (12), pp.1732-1734. ⟨10.1016/j.chom.2021.11.007⟩
Journal articles hal-03475729v1
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Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine and polymorphism in Plasmodium falciparum kelch13-propeller gene in Equatorial Guinea

Matilde Riloha Rivas , Marian Warsame , Ramona Mbá Andeme , Salomón Nsue Esidang , Policarpo Ricardo Ncogo
Malaria Journal, 2021, 20 (1), pp.275. ⟨10.1186/s12936-021-03807-x⟩
Journal articles pasteur-03273687v1
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Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

Barbara H. Stokes , Satish K. Dhingra , Kelly Rubiano , Sachel Mok , Judith Straimer
eLife, 2021, 10, pp.e66277. ⟨10.7554/eLife.66277⟩
Journal articles pasteur-03291682v1
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Dynamics of G6PD activity in patients receiving weekly primaquine for therapy of Plasmodium vivax malaria

Walter Taylor , Saorin Kim , Sim Kheng , Sinoun Muth , Pety Tor
PLoS Neglected Tropical Diseases, 2021, 15 (9), pp.e0009690. ⟨10.1371/journal.pntd.0009690⟩
Journal articles hal-03788876v1
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Genetic diversity of Plasmodium falciparum populations in three malaria transmission settings in Madagascar

Fanomezantsoa Ralinoro , Tovonahary Angelo Rakotomanga , Rianasoambolanoro Rakotosaona , Danielle A. Doll Rakoto , Didier Menard
Malaria Journal, 2021, 20 (1), pp.239. ⟨10.1186/s12936-021-03776-1⟩
Journal articles pasteur-03274270v1
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Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis

Daniel Pfeffer , Benedikt Ley , Rosalind Howes , Patrick Adu , Mohammad Shafiul Alam
PLoS Medicine, 2020, 17 (5), pp.e1003084. ⟨10.1371/journal.pmed.1003084⟩
Journal articles pasteur-02865146v1
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Keep the quality high: the benefits of lot testing for the quality control of malaria rapid diagnostic tests

Sandra Incardona , David Bell , Ana Campillo , Jane Cunningham , Frederic Ariey
Malaria Journal, 2020, 19 (1), pp.247. ⟨10.1186/s12936-020-03324-3⟩
Journal articles pasteur-03274278v1
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RIFINing Plasmodium–NK Cell Interaction

Didier Menard , Sandrine Houzé , Nicolas Papon
Trends in Parasitology, 2020, 36 (10), pp.802-804. ⟨10.1016/⟩
Journal articles hal-02942836v1
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Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda

Aline Uwimana , Eric Legrand , Barbara Stokes , Jean-Louis Mangala Ndikumana , Marian Warsame
Nature Medicine, 2020, ⟨10.1038/s41591-020-1005-2⟩
Journal articles pasteur-02911712v1
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Molecular assessment of kelch13 non-synonymous mutations in Plasmodium falciparum isolates from Central African Republic (2017–2019)

Romaric Nzoumbou-Boko , Chris-Boris Gildas Panté-Wockama , Carine Ngoagoni , Nathalie Petiot , Eric Legrand
Malaria Journal, 2020, 19 (1), ⟨10.1186/s12936-020-03264-y⟩
Journal articles pasteur-02735339v1
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Knowing the enemy: genetics to track antimalarial resistance

Didier Menard , Alfredo Mayor
The Lancet Infectious Diseases, 2020, 20 (12), pp.1361-1362. ⟨10.1016/S1473-3099(20)30271-1⟩
Journal articles pasteur-03274276v1
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Effect of mass dihydroartemisinin–piperaquine administration in southern Mozambique on the carriage of molecular markers of antimalarial resistance

Himanshu Gupta , Beatriz Galatas , Arlindo Chidimatembue , Silvie Huijben , Pau Cisteró
PLoS ONE, 2020, 15 (10), pp.e0240174. ⟨10.1371/journal.pone.0240174⟩
Journal articles pasteur-03274274v1
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DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites

Flore Nardella , Ludovic Halby , Elie Hammam , Diane Erdmann , Véronique Cadet-Daniel
ACS Central Science, 2020, 6 (1), pp.16-21. ⟨10.1021/acscentsci.9b00874⟩
Journal articles hal-02571983v1
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Towards harmonization of microscopy methods for malaria clinical research studies

Mehul Dhorda , El Hadji Ba , J. Kevin Baird , John Barnwell , David Bell
Malaria Journal, 2020, 19 (1), pp.324. ⟨10.1186/s12936-020-03352-z⟩
Journal articles pasteur-03274273v1
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WHO malaria nucleic acid amplification test external quality assessment scheme: results of distribution programmes one to three

Jane Cunningham , Rebecca Thomson , Sean Murphy , Maria de La Paz Ade , Xavier Ding
Malaria Journal, 2020, 19, pp.129. ⟨10.1186/s12936-020-03200-0⟩
Journal articles hal-02558622v1
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Significant efficacy of single low dose primaquine compared to stand alone artemisinin combination therapy in reducing gametocyte carriage in Cambodian patients with uncomplicated multidrug resistant Plasmodium falciparum malaria

Amélie Vantaux , Saorin Kim , Eakpor Piv , Sophy Chy , Laura Berne
Antimicrobial Agents and Chemotherapy, inPress, ⟨10.1128/AAC.02108-19⟩
Journal articles pasteur-02865145v2

Recrudescence, Reinfection, or Relapse? A More Rigorous Framework to Assess Chloroquine Efficacy for Plasmodium vivax Malaria

Jean Popovici , Lindsey Pierce-Friedrich , Saorin Kim , Sophalai Bin , Vorleak Run
Journal of Infectious Diseases, 2019, 219 (2), pp.315-322. ⟨10.1093/infdis/jiy484⟩
Journal articles hal-02558703v1

A review of the WHO malaria rapid diagnostic test product testing programme (2008–2018): performance, procurement and policy

Jane Cunningham , Sophie Jones , Michelle Gatton , John Barnwell , Qin Cheng
Malaria Journal, 2019, 18 (1), pp.387. ⟨10.1186/s12936-019-3028-z⟩
Journal articles hal-02558648v1
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Lack of quadruple and quintuple mutant alleles associated with sulfadoxine-pyrimethamine resistance in Plasmodium vivax isolates from Brazilian endemic areas

Larissa Rodrigues Gomes , Aline Lavigne , Patrícia Brasil , Cassio Leonel Peterka , Didier Ménard
Memórias do Instituto Oswaldo Cruz, 2019, 114, pp.e180425. ⟨10.1590/0074-02760180425⟩
Journal articles hal-02558679v1
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African isolates show a high proportion of multiple copies of the Plasmodium falciparum plasmepsin-2 gene, a piperaquine resistance marker

Didier Leroy , Fiona Macintyre , Yeka Adoke , Serge Ouoba , Aissata Barry
Malaria Journal, 2019, 18, pp.126. ⟨10.1186/s12936-019-2756-4⟩
Journal articles hal-02558674v1
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Households or Hotspots? Defining Intervention Targets for Malaria Elimination in Ratanakiri Province, Eastern Cambodia

Melanie Bannister-Tyrrell , Meryam Krit , Vincent Sluydts , Sochantha Tho , Mao Sokny
Journal of Infectious Diseases, 2019, 220 (6), pp.1034-1043. ⟨10.1093/infdis/jiz211⟩
Journal articles hal-02558670v1
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Hemolytic Dynamics of Weekly Primaquine Antirelapse Therapy Among Cambodians With Acute Plasmodium vivax Malaria With or Without Glucose-6-Phosphate Dehydrogenase Deficiency

Walter Taylor , Sim Kheng , Sinoun Muth , Pety Tor , Saorin Kim
Journal of Infectious Diseases, 2019, 220 (11), pp.1750-1760. ⟨10.1093/infdis/jiz313⟩
Journal articles hal-02558656v1

In vitro activity of ferroquine against artemisinin-based combination therapy (ACT)-resistant Plasmodium falciparum isolates from Cambodia

Mélissa Mairet-Khedim , Flore Nardella , Nimol Khim , Saorin Kim , Nimol Kloeung
Journal of Antimicrobial Chemotherapy, 2019, 74 (11), pp.3240-3244. ⟨10.1093/jac/dkz340⟩
Journal articles pasteur-02385376v1
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Performance of the Access Bio/CareStart rapid diagnostic test for the detection of glucose-6-phosphate dehydrogenase deficiency: A systematic review and meta-analysis

Benedikt Ley , Ari Winasti Satyagraha , Hisni Rahmat , Michael von Fricken , Nicholas Douglas
PLoS Medicine, 2019, 16 (12), pp.e1002992. ⟨10.1371/journal.pmed.1002992⟩
Journal articles hal-02558644v1

Accelerated evolution and spread of multidrug-resistant Plasmodium falciparum takes down the latest first-line antimalarial drug in southeast Asia

Didier Ménard , David Fidock
The Lancet Infectious Diseases, 2019, 19 (9), pp.916-917. ⟨10.1016/S1473-3099(19)30394-9⟩
Journal articles hal-02558660v1

Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes

Adam Kim , Jean Popovici , Didier Ménard , David Serre
Nature Communications, 2019, 10 (1), pp.371. ⟨10.1038/s41467-019-08312-z⟩
Journal articles hal-02558688v1
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Molecular characterization and mapping of glucose-6-phosphate dehydrogenase (G6PD) mutations in the Greater Mekong Subregion

Germana Bancone , Didier Ménard , Nimol Khim , Saorin Kim , Lydie Canier
Malaria Journal, 2019, 18 (1), pp.20. ⟨10.1186/s12936-019-2652-y⟩
Journal articles hal-02558683v1
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The tolerability of single low dose primaquine in glucose-6-phosphate deficient and normal falciparum-infected Cambodians

Lek Dysoley , Saorin Kim , Sergio Lopes , Nimol Khim , Steven Bjorges
BMC Infectious Diseases, 2019, 19 (1), pp.250. ⟨10.1186/s12879-019-3862-1⟩
Journal articles inserm-02289019v1

Plasmodium falciparum resistance to piperaquine driven by PfCRT

Satish Dhingra , Jennifer Small-Saunders , Didier Ménard , David Fidock
The Lancet Infectious Diseases, 2019, 19 (11), pp.1168-1169. ⟨10.1016/S1473-3099(19)30543-2⟩
Journal articles hal-02558651v1
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Efficacy and safety of artemisinin-based combination therapy, and molecular markers for artemisinin and piperaquine resistance in Mainland Tanzania

Mwaka Kakolwa , Muhidin Mahende , Deus Ishengoma , Celine Mandara , Billy Ngasala
Malaria Journal, 2018, 17, pp.369. ⟨10.1186/s12936-018-2524-x⟩
Journal articles hal-02558696v1
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Efficacy of artemisinin-based combination therapies and prevalence of molecular markers associated with artemisinin, piperaquine and sulfadoxine-pyrimethamine resistance in Sierra Leone

Samuel J. Smith , Anitta R.Y. Kamara , Foday Sahr , Mohamed Samai , Alpha Swaray
Acta Tropica, 2018, 185, pp.363-370. ⟨10.1016/j.actatropica.2018.06.016⟩
Journal articles hal-02558717v1

Closing in on the Reservoir: Proactive Case Detection in High-Risk Groups as a Strategy to Detect Plasmodium falciparum Asymptomatic Carriers in Cambodia

Gabriele Rossi , Lieven Vernaeve , Rafael van den Bergh , Chea Nguon , Mark Debackere
Clinical Infectious Diseases, 2018, 66 (10), pp.1610-1617. ⟨10.1093/cid/cix1064⟩
Journal articles hal-02559266v1
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Efficacy of artesunate–amodiaquine in the treatment of falciparum uncomplicated malaria in Madagascar

Oméga Raobela , Valérie Andriantsoanirina , David Gael Rajaonera , Tovonahary Angelo Rakotomanga , Stéphane Rabearimanana
Malaria Journal, 2018, 17, pp.284. ⟨10.1186/s12936-018-2440-0⟩
Journal articles hal-02558706v1
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Therapeutic and Transmission-Blocking Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia

Jean Popovici , Amélie Vantaux , Lyse Primault , Reingsey Samreth , Eak Por Piv
Emerging Infectious Diseases, 2018, 24 (8), pp.1516-1519. ⟨10.3201/eid2408.170768⟩
Journal articles hal-02558722v1
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Prevalence and risk factors for asymptomatic malaria and genotyping of glucose 6-phosphate (G6PD) deficiencies in a vivax-predominant setting, Lao PDR: implications for sub-national elimination goals

Andrew Lover , Emily Dantzer , Bouasy Hongvanthong , Keobouphaphone Chindavongsa , Susie Welty
Malaria Journal, 2018, 17, pp.218. ⟨10.1186/s12936-018-2367-5⟩
Journal articles hal-02558720v1

Contribution to Malaria Transmission of Symptomatic and Asymptomatic Parasite Carriers in Cambodia

Amélie Vantaux , Reingsey Samreth , Eakpor Piv , Nimol Khim , Saorin Kim
Journal of Infectious Diseases, 2018, 217 (10), pp.1561-1568. ⟨10.1093/infdis/jiy060⟩
Journal articles hal-02559258v1

Absence of K13 Polymorphism in Plasmodium falciparum from Brazilian Areas Where the Parasite Is Endemic

Larissa Rodrigues Gomes , Aline Lavigne , Cassio Leonel Peterka , Patrícia Brasil , Didier Ménard
Antimicrobial Agents and Chemotherapy, 2018, 62 (10), ⟨10.1128/AAC.00354-18⟩
Journal articles hal-02558713v1
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A Novel Single-Nucleotide Polymorphism Loop Mediated Isothermal Amplification Assay for Detection of Artemisinin-Resistant Plasmodium falciparum Malaria

Abu Naser Mohon , Didier Ménard , Mohammad Shafiul Alam , Kevin Perera , Dylan Pillai
Open Forum Infectious Diseases, 2018, 5 (4), pp.ofy011. ⟨10.1093/ofid/ofy011⟩
Journal articles hal-02559242v1

Adapting Reactive Case Detection Strategies for falciparum Malaria in a Low-Transmission Area in Cambodia

Gabriele Rossi , Rafael van den Bergh , Chea Nguon , Mark Debackere , Lieven Vernaeve
Clinical Infectious Diseases, 2018, 66 (2), pp.296-298. ⟨10.1093/cid/cix781⟩
Journal articles hal-02559291v1

Endoperoxide-based compounds: cross-resistance with artemisinins and selection of a Plasmodium falciparum lineage with a K13 non-synonymous polymorphism

Lucie Paloque , Benoit Witkowski , Joël Lelièvre , Manel Ouji , Tanila Ben Haddou
Journal of Antimicrobial Chemotherapy, 2018, 73 (2), pp.395-403. ⟨10.1093/jac/dkx412⟩
Journal articles hal-01963522v1
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Importance of household-level risk factors in explaining micro-epidemiology of asymptomatic malaria infections in Ratanakiri Province, Cambodia

Melanie Bannister-Tyrrell , Set Srun , Vincent Sluydts , Charlotte Gryseels , Vanna Mean
Scientific Reports, 2018, 8, pp.11643. ⟨10.1038/s41598-018-30193-3⟩
Journal articles hal-02558708v1
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Targeting a Reticulocyte Binding Protein and Duffy Binding Protein to Inhibit Reticulocyte Invasion by Plasmodium vivax

Sonal Gupta , Shailja Singh , Jean Popovici , Camille Roesch , Ahmed Rushdi Shakri
Scientific Reports, 2018, 8, pp.10511. ⟨10.1038/s41598-018-28757-4⟩
Journal articles hal-02558715v1
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Tools for surveillance of anti-malarial drug resistance: an assessment of the current landscape

Christian Nsanzabana , Djibrine Djalle , Philippe Guérin , Didier Ménard , Iveth Gonzalez
Malaria Journal, 2018, 17 (1), pp.75. ⟨10.1186/s12936-018-2185-9⟩
Journal articles pasteur-02865083v1
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A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants

Laurence Vachot-Ganée , Nimol Khim , Alexandra Iannello , Eric Legrand , Saorin Kim
Malaria Journal, 2018, 17 (1), pp.175. ⟨10.1186/s12936-018-2329-y⟩
Journal articles pasteur-01813852v1
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Genetic diversity in two Plasmodium vivax protein ligands for reticulocyte invasion

Camille Roesch , Jean Popovici , Sophalai Bin , Vorleak Run , Saorin Kim
PLoS Neglected Tropical Diseases, 2018, 12 (10), pp.e0006555. ⟨10.1371/journal.pntd.0006555⟩
Journal articles pasteur-01912544v1
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Multidrug-resistant Plasmodium falciparum malaria in the Greater Mekong subregion

Didier Ménard , Jérôme Clain , Frédéric Ariey
The Lancet Infectious Diseases, 2018, 18 (3), pp.238-239. ⟨10.1016/S1473-3099(18)30071-9⟩
Journal articles hal-02559257v1
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Asymptomatic Plasmodium vivax infections among Duffy-negative population in Kedougou, Senegal

Makhtar Niang , Rokhaya Sane , Abdourahmane Sow , Bacary Sadio , Sophy Chy
Tropical Medicine and Health, 2018, 46, pp.45. ⟨10.1186/s41182-018-0128-3⟩
Journal articles hal-02558691v1
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Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

Leila Ross , Satish Dhingra , Sachel Mok , Tomas Yeo , Kathryn Wicht
Nature Communications, 2018, 9 (1), pp.3314. ⟨10.1038/s41467-018-05652-0⟩
Journal articles hal-02558701v1
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Genomic Analyses Reveal the Common Occurrence and Complexity of Plasmodium vivax Relapses in Cambodia

Jean Popovici , Lindsey Friedrich , Saorin Kim , Sophalai Bin , Vorleak Run
mBio, 2018, 9 (1), pp.e01888-17. ⟨10.1128/mBio.01888-17⟩
Journal articles hal-02559262v1
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Plasmepsin II–III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium falciparum

Selina Bopp , Pamela Magistrado , Wesley Wong , Stephen Schaffner , Angana Mukherjee
Nature Communications, 2018, 9 (1), pp.1769. ⟨10.1038/s41467-018-04104-z⟩
Journal articles hal-02558725v1
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Drug-Resistant Polymorphisms and Copy Numbers in Plasmodium falciparum, Mozambique, 2015

Himanshu Gupta , Eusebio Macete , Helder Bulo , Crizolgo Salvador , Marian Warsame
Emerging Infectious Diseases, 2018, 24 (1), pp.40-48. ⟨10.3201/eid2401.170864⟩
Journal articles pasteur-02865089v1
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Identification and characterization of areas of high and low risk for asymptomatic malaria infections at sub-village level in Ratanakiri, Cambodia

Lies Durnez , Myrthe Pareyn , Vanna Mean , Saorin Kim , Nimol Khim
Malaria Journal, 2018, 17 (1), pp.27. ⟨10.1186/s12936-017-2169-1⟩
Journal articles hal-02559268v1

Emergence of Plasmodium falciparum triple mutant in Cambodia

Gabriele Rossi , Martin de Smet , Nimol Khim , Jean-Marie Kindermans , Didier Ménard
The Lancet Infectious Diseases, 2017, 17 (12), pp.1233. ⟨10.1016/S1473-3099(17)30635-7⟩
Journal articles hal-02559287v1
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Characterization of P. vivax blood stage transcriptomes from field isolates reveals similarities among infections and complex gene isoforms

Adam Kim , Jean Popovici , Amélie Vantaux , Reingsey Samreth , Sophalai Bin
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-07275-9⟩
Journal articles inserm-01625796v1

Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa

Feng Lu , Richard Culleton , Meihua Zhang , Abhinay Ramaprasad , Lorenz von Seidlein
New England Journal of Medicine, 2017, 376 (10), pp.991-993. ⟨10.1056/NEJMc1612765⟩
Journal articles hal-02559320v1

Performance of Rapid Diagnostic Testing in Patients with Suspected Malaria in Cambodia, a Low-Endemicity Country Aiming for Malaria Elimination

Gabriele Rossi , Martin de Smet , Nimol Khim , Jean-Marie Kindermans , Didier Ménard
Clinical Infectious Diseases, 2017, 65 (10), pp.1769-1770. ⟨10.1093/cid/cix625⟩
Journal articles hal-02559293v1

Antimalarial Drug Resistance: A Threat to Malaria Elimination

Didier Ménard , Arjen M Dondorp
Cold Spring Harbor Perspectives in Medicine, 2017, 7 (7), pp.a025619. ⟨10.1101/cshperspect.a025619⟩
Journal articles hal-02559309v1

Modelling primaquine-induced haemolysis in G6PD deficiency

James Watson , Walter Rj Taylor , Didier Ménard , Sim Kheng , Nicholas J White
Journal articles hal-02559330v1
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The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study

Mallika Imwong , Kanokon Suwannasin , Chanon Kunasol , Kreepol Sutawong , Mayfong Mayxay
The Lancet Infectious Diseases, 2017, 17 (5), pp.491-497. ⟨10.1016/S1473-3099(17)30048-8⟩
Journal articles hal-02559325v1
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Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia

Ankit Dwivedi , Christelle Reynes , Axel Kuehn , Daniel Barry Roche , Nimol Khim
Malaria Journal, 2017, 16 (1), pp.493. ⟨10.1186/s12936-017-2140-1⟩
Journal articles inserm-01672315v1

Prevalence of K13 mutation and Day-3 positive parasitaemia in artemisinin-resistant malaria endemic area of Cambodia: a cross-sectional study

Soy Ty Kheang , Siv Sovannaroth , Sovann Ek , Say Chy , Phally Chhun
Malaria Journal, 2017, 16 (1), pp.372. ⟨10.1186/s12936-017-2024-4⟩
Journal articles hal-02559298v1
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Plasmodium vivax multidrug resistance-1 gene polymorphism in French Guiana

Emilie Faway , Lise Musset , Stéphane Pelleau , Béatrice Volney , Jessica Casteras
Malaria Journal, 2016, 15 (1), pp.540. ⟨10.1186/s12936-016-1595-9⟩
Journal articles pasteur-01400964v1
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Efficacy of topical mosquito repellent (picaridin) plus long-lasting insecticidal nets versus long-lasting insecticidal nets alone for control of malaria: a cluster randomised controlled trial

Vincent Sluydts , Lies Durnez , Somony Heng , Charlotte Gryseels , Lydie Canier
The Lancet Infectious Diseases, 2016, 16 (10), pp.1169-1177. ⟨10.1016/S1473-3099(16)30148-7⟩
Journal articles hal-02560616v1
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Plasmodium vivax Malaria in Cambodia

Sovannaroth Siv , Arantxa Roca-Feltrer , Seshu Babu Vinjamuri , Denis Mey Bouth , Dysoley Lek
American Journal of Tropical Medicine and Hygiene, 2016, 95 (6 Suppl), pp.97-107. ⟨10.4269/ajtmh.16-0208⟩
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Geographical patterns of malaria transmission based on serological markers for falciparum and vivax malaria in Ratanakiri, Cambodia

Karen Kerkhof , Vincent Sluydts , Somony Heng , Saorin Kim , Myrthe Pareyn
Malaria Journal, 2016, 15, pp.510. ⟨10.1186/s12936-016-1558-1⟩
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Low-grade sulfadoxine–pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola

Elsa Kaingona-Daniel , Larissa Rodrigues Gomes , Bianca Gama , Natália Almeida-De-Oliveira , Filomeno Fortes
Malaria Journal, 2016, 15 (1), pp.309. ⟨10.1186/s12936-016-1358-7⟩
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Serological markers to measure recent changes in malaria at population level in Cambodia

Karen Kerkhof , Vincent Sluydts , Laura Willen , Saorin Kim , Lydie Canier
Malaria Journal, 2016, 15 (1), pp.529. ⟨10.1186/s12936-016-1576-z⟩
Journal articles hal-02560602v1
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Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes.

Johann Beghain , Anne-Claire Langlois , Eric Legrand , Laura Grange , Nimol Khim
Malaria Journal, 2016, 15 (1), pp.206. ⟨10.1186/s12936-016-1258-x⟩
Journal articles pasteur-01303621v1

Role of K13 Mutations in Artemisinin-Based Combination Therapy

Charlotte Rasmussen , Frédéric Ariey , Rick M. Fairhurst , Pascal Ringwald , Didier Ménard
Clinical Infectious Diseases, 2016, 63 (12), pp.1680-1681. ⟨10.1093/cid/ciw641⟩
Journal articles hal-02560610v1
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Identification and Characterization of Two Novel RNA Viruses from Anopheles gambiae Species Complex Mosquitoes

Guillaume Carissimo , Karin Eiglmeier , Julie Reveillaud , Inge Holm , Mawlouth Diallo
PLoS ONE, 2016, 11 (5), pp.e0153881. ⟨10.1371/journal.pone.0153881⟩
Journal articles hal-01316516v1
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A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study

Benoit Witkowski , Valentine Duru , Nimol Khim , Leila S Ross , Benjamin Saintpierre
The Lancet Infectious Diseases, 2016, 17 (2), pp.174-183. ⟨10.1016/S1473-3099(16)30415-7⟩
Journal articles pasteur-01400955v1
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An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia

Rithea Leang , Naw Htee Khu , Mavuto Mukaka , Mark Debackere , Rupam Tripura
BMC Medicine, 2016, 14 (1), pp.171. ⟨10.1186/s12916-016-0701-8⟩
Journal articles pasteur-01739357v1
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Artemisinin-Resistant Plasmodium falciparum K13 Mutant Alleles, Thailand–Myanmar Border

Mikaël Boullé , Benoit Witkowski , Valentine Duru , Kanlaya Sriprawat , Shalini Nair
Emerging Infectious Diseases, 2016, 22 (8), pp.1503-1505. ⟨10.3201/eid2208.160004⟩
Journal articles hal-02560612v1
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Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia

Eric P.M Grist , Jennifer Flegg , Georgina Humphreys , Ignacio Suay Mas , Tim J.C. Anderson
International Journal of Health Geographics, 2016, 15 (1), pp.37. ⟨10.1186/s12942-016-0064-6⟩
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Efficacy and Safety of Pyronaridine-Artesunate for Treatment of Uncomplicated Plasmodium falciparum Malaria in Western Cambodia

Rithea Leang , Sara Canavati , Nimol Khim , Lasse Vestergaard , Isabelle Borghini Fuhrer
Antimicrobial Agents and Chemotherapy, 2016, 60 (7), pp.3884-3890. ⟨10.1128/AAC.00039-16⟩
Journal articles hal-02560635v1

National Malaria Prevalence in Cambodia: Microscopy Versus Polymerase Chain Reaction Estimates

Dysoley Lek , Jean Popovici , Frédéric Ariey , Seshu Babu Vinjamuri , Sylvia Meek
American Journal of Tropical Medicine and Hygiene, 2016, 95 (3), pp.588-594. ⟨10.4269/ajtmh.15-0908⟩
Journal articles hal-02560614v1
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Complexity of Infection and Genetic Diversity in Cambodian Plasmodium vivax

Lindsey Friedrich , Jean Popovici , Saorin Kim , Lek Dysoley , Peter A Zimmerman
PLoS Neglected Tropical Diseases, 2016, 10 (3), pp.e0004526. ⟨10.1371/journal.pntd.0004526⟩
Journal articles hal-02560632v1
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Reactive case-detection of malaria in Pailin Province, Western Cambodia: lessons from a year-long evaluation in a pre-elimination setting

John Hustedt , Sara Canavati , Chandary Rang , Ruth Ashton , Nimol Khim
Malaria Journal, 2016, 15 (1), pp.132. ⟨10.1186/s12936-016-1191-z⟩
Journal articles hal-02560633v1
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Plasmodium falciparum parasite population structure and gene flow associated to anti-malarial drugs resistance in Cambodia

Ankit Dwivedi , Nimol Khim , Christelle Reynes , Patrice Ravel , Laurence Ma
Malaria Journal, 2016, 15, pp.319. ⟨10.1186/s12936-016-1370-y⟩
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Plasmodium vivax mdr1 genotypes in isolates from successfully cured patients living in endemic and non-endemic Brazilian areas

Larissa Rodrigues Gomes , Natália Ketrin Almeida-De-Oliveira , Aline Rosa de Lavigne , Suelen Rezende Félix de Lima , Anielle de Pina-Costa
Malaria Journal, 2016, 15, pp.96. ⟨10.1186/s12936-016-1141-9⟩
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A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

Didier Ménard , Nimol Khim , Johann Beghain , Ayola A Adegnika , Mohammad Shafiul-Alam
New England Journal of Medicine, 2016, 374 (25), pp.2453-64. ⟨10.1056/NEJMoa1513137⟩
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Plasmodium falciparum Resistance to Artemisinin Derivatives and Piperaquine: A Major Challenge for Malaria Elimination in Cambodia

Valentine Duru , Benoit Witkowski , Didier Ménard
American Journal of Tropical Medicine and Hygiene, 2016, 95 (6), pp.1228-1238. ⟨10.4269/ajtmh.16-0234⟩
Journal articles hal-02560596v1
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Tolerability and safety of weekly primaquine against relapse of Plasmodium vivax in Cambodians with glucose-6-phosphate dehydrogenase deficiency

Sim Kheng , Sinoun Muth , Walter Taylor , Narann Tops , Khem Kosal
BMC Medicine, 2015, 13 (1), pp.203. ⟨10.1186/s12916-015-0441-1⟩
Journal articles hal-02560647v1

Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment

Rithea Leang , Walter Taylor , Denis Mey Bouth , Lijiang Song , Joel Tarning
Antimicrobial Agents and Chemotherapy, 2015, 59 (8), pp.4719-4726. ⟨10.1128/AAC.00835-15⟩
Journal articles hal-02560651v1
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Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations

Valentine Duru , Nimol Khim , Rithea Leang , Saorin Kim , Anais Domergue
BMC Medicine, 2015, 13 (1), pp.305. ⟨10.1186/s12916-015-0539-5⟩
Journal articles hal-02560638v1
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Towards real-time monitoring of artemisinin resistance

Didier Ménard , Frédéric Ariey
The Lancet Infectious Diseases, 2015, 15 (4), pp.367-368. ⟨10.1016/S1473-3099(15)70046-0⟩
Journal articles hal-02560654v1
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Novel Cross-Border Approaches to Optimise Identification of Asymptomatic and Artemisinin-Resistant Plasmodium Infection in Mobile Populations Crossing Cambodian Borders

Hannah Edwards , Sara Canavati , Chandary Rang , Po Ly , Siv Sovannaroth
PLoS ONE, 2015, 10 (9), pp.e0124300. ⟨10.1371/journal.pone.0124300⟩
Journal articles hal-02560641v1
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Implementation and application of a multiplex assay to detect malaria-specific antibodies: a promising tool for assessing malaria transmission in Southeast Asian pre-elimination areas

Karen Kerkhof , Lydie Canier , Saorin Kim , Somony Heng , Tho Sochantha
Malaria Journal, 2015, 14 (338), pp.1-14. ⟨10.1186/s12936-015-0868-z⟩
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Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay.

Louis-Jérôme Leba , Lise Musset , Stéphane Pelleau , Yannick Estevez , Caroline Birer
Malaria Journal, 2015, 14, pp.234. ⟨10.1186/s12936-015-0752-x⟩
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Challenges in Antimalarial Drug Treatment for Vivax Malaria Control

Jean Popovici , Didier Ménard
Trends in Molecular Medicine, 2015, 21 (12), pp.776-788. ⟨10.1016/j.molmed.2015.10.004⟩
Journal articles hal-02560639v1

Plasmodium vivax Diversity and Population Structure across Four Continents

Cristian Koepfli , Priscila T Rodrigues , Tiago Antao , Pamela Orjuela-Sánchez , Peter van den Eede
PLoS Neglected Tropical Diseases, 2015, 9 (6), pp.e0003872. ⟨10.1371/journal.pntd.0003872⟩
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K13-Propeller Polymorphisms in Plasmodium falciparum Isolates from Patients in Mayotte in 2013 and 2014

Marylin Torrentino-Madamet , Louis Collet , Jean François Lepère , Nicolas Benoit , Remy Amalvict
Antimicrobial Agents and Chemotherapy, 2015, 59 (12), pp.7878-7881. ⟨10.1128/AAC.01251-15⟩
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Histone Methyltransferase Inhibitors Are Orally Bioavailable, Fast-Acting Molecules with Activity against Different Species Causing Malaria in Humans

Nicholas Malmquist , Sandeep Sundriyal , Joachim Caron , Patty Chen , Benoit Witkowski
Antimicrobial Agents and Chemotherapy, 2015, 59 (2), pp.950-959. ⟨10.1128/AAC.04419-14⟩
Journal articles hal-02560661v1
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Malaria rapid diagnostic test as point-of-care test: study protocol for evaluating the VIKIA® Malaria Ag Pf/Pan

Saorin Kim , Sina Nhem , Dany Dourng , Didier Ménard
Malaria Journal, 2015, 14 (1), pp.114. ⟨10.1186/s12936-015-0633-3⟩
Journal articles hal-02560652v1
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The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data

Martin Adjuik , Richard Allan , Anupkumar Anvikar , Elizabeth Ashley , Mamadou Fallou Ba
BMC Medicine, 2015, 13 (1), pp.66. ⟨10.1186/s12916-015-0301-z⟩
Journal articles hal-02560653v1

K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

Judith Straimer , Nina F. Gnadig , Benoit Witkowski , Chanaki Amaratunga , Valentine Duru
Science, 2015, 347 (6220), pp.428-431. ⟨10.1126/science.1260867⟩
Journal articles hal-01925134v1

Malaria PCR Detection in Cambodian Low-Transmission Settings: Dried Blood Spots Versus Venous Blood Samples

Lydie Canier , Nimol Khim , Saorin Kim , Rotha Eam , Chanra Khean
American Journal of Tropical Medicine and Hygiene, 2015, 92 (3), pp.573-577. ⟨10.4269/ajtmh.14-0614⟩
Journal articles hal-02560656v1

Independent Emergence of Artemisinin Resistance Mutations Among Plasmodium falciparum in Southeast Asia

Shannon Takala-Harrison , Christopher Jacob , Cesar Arze , Michael Cummings , Joana Silva
Journal of Infectious Diseases, 2015, 211 (5), pp.670-679. ⟨10.1093/infdis/jiu491⟩
Journal articles hal-02560668v1

Plasmodium falciparum Founder Populations in Western Cambodia Have Reduced Artemisinin Sensitivity In Vitro

Chanaki Amaratunga , Benoit Witkowski , Dalin Dek , Vorleak Try , Nimol Khim
Antimicrobial Agents and Chemotherapy, 2014, 58 (8), pp.4935-4937. ⟨10.1128/AAC.03055-14⟩
Journal articles hal-02560673v1

Genetic diversity of VAR2CSA ID1-DBL2Xb in worldwide Plasmodium falciparum populations: Impact on vaccine design for placental malaria

Bita Bordbar , Nicaise Tuikue Ndam , Emmanuelle Renard , Sayeh Jafari-Guemouri , Livingstone Tavul
Infection, Genetics and Evolution, 2014, 25, pp.81-92. ⟨10.1016/j.meegid.2014.04.010⟩
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Field Trial Evaluation of the Performances of Point-of-Care Tests for Screening G6PD Deficiency in Cambodia

Arantxa Roca-Feltrer , Nimol Khim , Saorin Kim , Sophy Chy , Lydie Canier
PLoS ONE, 2014, 9 (12), pp.e116143. ⟨10.1371/journal.pone.0116143⟩
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Effects of mefloquine use on Plasmodium vivax multidrug resistance.

Nimol Khim , Voahangy Andrianaranjaka , Jean Popovici , Saorin Kim , Arsene Ratsimbasoa
Emerging Infectious Diseases, 2014, 20 (10), pp.1637-44. ⟨10.3201/eid2010.140411⟩
Journal articles pasteur-01109696v1
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A molecular marker of artemisinin-resistant Plasmodium falciparum malaria.

Frédéric Ariey , Benoit Witkowski , Chanaki Amaratunga , Johann Beghain , Anne-Claire Langlois
Nature, 2014, 505 (7481), pp.50-5. ⟨10.1038/nature12876⟩
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Reduced Polymorphism in the Kelch Propeller Domain in Plasmodium vivax Isolates from Cambodia

Jean Popovici , Sokheng Kao , Leanghor Eal , Sophalai Bin , Saorin Kim
Antimicrobial Agents and Chemotherapy, 2014, 59 (1), pp.730-733. ⟨10.1128/AAC.03908-14⟩
Journal articles hal-02560662v1

Genetic diversity and population structure of Plasmodium vivax isolates from Sudan, Madagascar, French Guiana and Armenia.

Michela Menegon , Durand Patrick , Didier Menard , Eric Legrand , Stéphane Picot
Infection, Genetics and Evolution, 2014, 27, pp.244-9. ⟨10.1016/j.meegid.2014.07.029⟩
Journal articles pasteur-01109682v1
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Polymorphisms in Plasmodium falciparum Chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors That Affect Treatment Outcomes for P. falciparum Malaria After Artemether-Lumefantrine and Artesunate-Amodiaquine

Meera Venkatesan , Nahla Gadalla , Kasia Stepniewska , Prabin Dahal , Christian Nsanzabana
American Journal of Tropical Medicine and Hygiene, 2014, 91 (4), pp.833-843. ⟨10.4269/ajtmh.14-0031⟩
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Spatial clustering and risk factors of malaria infections in Ratanakiri Province, Cambodia

Vincent Sluydts , Somony Heng , Marc Coosemans , Karel van Roey , Charlotte Gryseels
Malaria Journal, 2014, 13 (1), pp.387. ⟨10.1186/1475-2875-13-387⟩
Journal articles hal-02560666v1

La résistance de P. falciparum à l’artémisinine

Nimol Khim , Benoit Witkowski , Valentine Duru , Frédéric Ariey , Odile Mercereau-Puijalon
Médecine/Sciences, 2014, 30 (8-9), pp.727-729. ⟨10.1051/medsci/20143008004⟩
Journal articles hal-02560669v1

Patterns of selection on Plasmodium falciparum erythrocyte-binding antigens after the colonization of the New World.

Erhan Yalcindag , Virginie Rougeron , Eric Elguero , Céline Arnathau , Durand Patrick
Molecular Ecology Notes, 2014, 23 (8), pp.1979-93. ⟨10.1111/mec.12696⟩
Journal articles pasteur-01109668v1
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Limited polymorphisms in k13 gene in Plasmodium falciparum isolates from Dakar, Senegal in 2012–2013

Marylin Torrentino-Madamet , Bécaye Fall , Nicolas Benoit , Cheikhou Camara , Remy Amalvict
Malaria Journal, 2014, 13 (1), pp.472. ⟨10.1186/1475-2875-13-472⟩
Journal articles hal-02560659v1

Molecular surveillance for artemisinin resistance in Africa

Cally Roper , Michael Alifrangis , Frédéric Ariey , Ambrose Talisuna , Didier Ménard
The Lancet Infectious Diseases, 2014, 14 (8), pp.668-670. ⟨10.1016/S1473-3099(14)70826-6⟩
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Artemisinin resistance in Plasmodium falciparum

Chanaki Amaratunga , Benoit Witkowski , Nimol Khim , Didier Ménard , Rick M Fairhurst
The Lancet Infectious Diseases, 2014, 14 (6), pp.449-450. ⟨10.1016/S1473-3099(14)70777-7⟩
Journal articles hal-02560674v1
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Plasmodium prevalence and artemisinin-resistant falciparum malaria in Preah Vihear Province, Cambodia: a cross-sectional population-based study

Philippe Bosman , Jorgen Stassijns , Fabienne Nackers , Lydie Canier , Nimol Kim
Malaria Journal, 2014, 13 (1), pp.394. ⟨10.1186/1475-2875-13-394⟩
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Acute Undifferentiated Febrile Illness in Rural Cambodia: A 3-Year Prospective Observational Study

Tara Mueller , Sovannaroth Siv , Nimol Khim , Saorin Kim , Erna Fleischmann
PLoS ONE, 2014, 9 (4), pp.e95868. ⟨10.1371/journal.pone.0095868⟩
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Reduced Artemisinin Susceptibility of Plasmodium falciparum Ring Stages in Western Cambodia

Benoît Witkowski , Nimol Khim , Pheaktra Chim , Saorin Kim , Sopheakvatey Ke
Antimicrobial Agents and Chemotherapy, 2013, 57 (2), pp.914-923. ⟨10.1128/AAC.01868-12⟩
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High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool.

Charles J Woodrow , Sabina Dahlström , Richard Cooksey , Jennifer A Flegg , Hervé Le Nagard
Antimicrobial Agents and Chemotherapy, 2013, 57 (7), pp.3121-30. ⟨10.1128/AAC.02350-12⟩
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Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies.

Benoit Witkowski , Chanaki Amaratunga , Nimol Khim , Sokunthea Sreng , Pheaktra Chim
The Lancet Infectious Diseases, 2013, epub ahead of print. ⟨10.1016/S1473-3099(13)70252-4⟩
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Whole genome sequencing of field isolates reveals a common duplication of the Duffy binding protein gene in Malagasy Plasmodium vivax strains.

Didier Menard , Ernest R Chan , Christophe Benedet , Arsène Ratsimbasoa , Saorin Kim
PLoS Neglected Tropical Diseases, 2013, 7 (11), pp.e2489. ⟨10.1371/journal.pntd.0002489⟩
Journal articles pasteur-01109627v1
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Global analysis of Plasmodium falciparum Na+/H+ exchanger (pfnhe-1) allele polymorphism and its usefulness as a marker of in vitro resistance to quinine

Didier Ménard , Valérie Andriantsoanirina , Nimol Khim , Arsène Ratsimbasoa , Benoit Witkowski
International Journal for Parasitology, 2013, 3, pp.8-19. ⟨10.1016/j.ijpddr.2012.10.001⟩
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In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound.

Anthony Bouillon , David Giganti , Christophe Benedet , Olivier Gorgette , Stéphane Pêtres
Journal of Biological Chemistry, 2013, 288, pp.18561-73. ⟨10.1074/jbc.M113.456764⟩
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Therapeutic efficacy of fixed dose artesunate-mefloquine for the treatment of acute, uncomplicated Plasmodium falciparum malaria in Kampong Speu, Cambodia.

Rithea Leang , Sakun Ros , Socheat Duong , Visweswaran Navaratnam , Pharath Lim
Malaria Journal, 2013, 12 (1), pp.343. ⟨10.1186/1475-2875-12-343⟩
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Reduced impact of pyrimethamine drug pressure on Plasmodium malariae dihydrofolate reductase gene.

Nimol Khim , Saorin Kim , Christiane Bouchier , Magali Tichit , Frédéric Ariey
Antimicrobial Agents and Chemotherapy, 2012, 56 (2), pp.863-8. ⟨10.1128/AAC.05284-11⟩
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Multiple independent introductions of Plasmodium falciparum in South America.

Erhan Yalcindag , Eric Elguero , Céline Arnathau , Durand Patrick , Jean Akiana
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (2), pp.511-6. ⟨10.1073/pnas.1119058109⟩
Journal articles pasteur-00705564v1
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Compliance, safety, and effectiveness of fixed-dose artesunate-amodiaquine for presumptive treatment of non-severe malaria in the context of home management of malaria in Madagascar.

Arsène Ratsimbasoa , Harintsoa Ravony , Jeanne-Aimée Vonimpaisomihanta , Rogelin Raherinjafy , Martial Jahevitra
American Journal of Tropical Medicine and Hygiene, 2012, 86 (2), pp.203-10. ⟨10.4269/ajtmh.2012.11-0047⟩
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Individual Plasmodium vivax msp1 variants within polyclonal P. vivax infections display different propensities for relapse.

Jessica T Lin , Jonathan J Juliano , Oksana Kharabora , Rithy Sem , Feng-Chang Lin
Journal of Clinical Microbiology, 2012, 50 (4), pp.1449-51. ⟨10.1128/JCM.06212-11⟩
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Whole Genome Sequencing of Field Isolates Provides Robust Characterization of Genetic Diversity in Plasmodium vivax.

Ernest R Chan , Didier Menard , Peter H David , Arsène Ratsimbasoa , Saorin Kim
PLoS Neglected Tropical Diseases, 2012, 6 (9), pp.e1811. ⟨10.1371/journal.pntd.0001811⟩
Journal articles pasteur-00741089v1
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Performance of "VIKIA Malaria Ag Pf/Pan" (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections.

Monidarin Chou , Saorin Kim , Nimol Khim , Sophy Chy , Sarorn Sum
Malaria Journal, 2012, 11 (1), pp.295. ⟨10.1186/1475-2875-11-295⟩
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Mapping the Aetiology of Non-Malarial Febrile Illness in Southeast Asia through a Systematic Review-Terra Incognita Impairing Treatment Policies.

Nathalie Acestor , Richard Cooksey , Paul N Newton , Didier Ménard , Philippe J Guerin
PLoS ONE, 2012, 7 (9), pp.e44269. ⟨10.1371/journal.pone.0044269⟩
Journal articles pasteur-00741092v1
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Management of uncomplicated malaria in febrile under five-year-old children by community health workers in Madagascar: reliability of malaria rapid diagnostic tests.

Arsène Ratsimbasoa , Harintsoa Ravony , Jeanne-Aimée Vonimpaisomihanta , Rogelin Raherinjafy , Martial Jahevitra
Malaria Journal, 2012, 11, pp.85. ⟨10.1186/1475-2875-11-85⟩
Journal articles pasteur-00741096v1
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Focused Screening and Treatment (FSAT): A PCR-Based Strategy to Detect Malaria Parasite Carriers and Contain Drug Resistant P. falciparum, Pailin, Cambodia.

Stefan Hoyer , Sokomar Nguon , Saorin Kim , Najibullah Habib , Nimol Khim
PLoS ONE, 2012, 7 (10), pp.e45797. ⟨10.1371/journal.pone.0045797⟩
Journal articles pasteur-00741087v1
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The global distribution of the Duffy blood group.

Rosalind E Howes , Anand P Patil , Frédéric B Piel , Oscar A Nyangiri , Caroline W Kabaria
Nature Communications, 2011, 2, pp.266. ⟨10.1038/ncomms1265⟩
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Plasmodium knowlesi infection in humans, Cambodia, 2007-2010.

Nimol Khim , Sovannaroth Siv , Saorin Kim , Tara Mueller , Erna Fleischmann
Emerging Infectious Diseases, 2011, 17 (10), pp.1900-2. ⟨10.3201/eid1710.110355⟩
Journal articles pasteur-00741110v1
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In vitro susceptibility to pyrimethamine of DHFR I164L single mutant Plasmodium falciparum

Valérie Andriantsoanirina , Rémy Durand , Bruno Pradines , Eric Baret , Christiane Bouchier
Malaria Journal, 2011, 10 (1), pp.283. ⟨10.1186/1475-2875-10-283⟩
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Performance of the CareStart™ G6PD deficiency screening test, a point-of-care diagnostic for primaquine therapy screening.

Saorin Kim , Chea Nguon , Bertrand Guillard , Socheat Duong , Sophy Chy
PLoS ONE, 2011, 6 (12), pp.e28357. ⟨10.1371/journal.pone.0028357⟩
Journal articles pasteur-00741113v1
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Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests.

Joanne Baker , Mei-Fong Ho , Anita Pelecanos , Michelle Gatton , Nanhua Chen
Malaria Journal, 2010, 9, pp.129. ⟨10.1186/1475-2875-9-129⟩
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Chloroquine clinical failures in P. falciparum malaria are associated with mutant Pfmdr-1, not Pfcrt in Madagascar.

Valérie Andriantsoanirina , Arsène Ratsimbasoa , Christiane Bouchier , Magali Tichit , Martial Jahevitra
PLoS ONE, 2010, 5 (10), pp.e13281. ⟨10.1371/journal.pone.0013281⟩
Journal articles pasteur-00557026v1
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Association of microsatellite variations of Plasmodium falciparum Na+/H+ exchanger (Pfnhe-1) gene with reduced in vitro susceptibility to quinine: lack of confirmation in clinical isolates from Africa.

Valérie Andriantsoanirina , Didier Ménard , Stéphane Rabearimanana , Véronique Hubert , Christiane Bouchier
American Journal of Tropical Medicine and Hygiene, 2010, 82 (5), pp.782-7. ⟨10.4269/ajtmh.2010.09-0327⟩
Journal articles pasteur-00557032v1
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Plasmodium vivax clinical malaria is commonly observed in Duffy-negative Malagasy people.

Didier Ménard , Céline Barnadas , Christiane Bouchier , Cara Henry-Halldin , Laurie R Gray
Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (13), pp.5967-71. ⟨10.1073/pnas.0912496107⟩
Journal articles pasteur-00741118v1
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Origins of the recent emergence of Plasmodium falciparum pyrimethamine resistance alleles in Madagascar.

Valérie Andriantsoanirina , Christiane Bouchier , Magali Tichit , Martial Jahevitra , Stéphane Rabearimanana
Antimicrobial Agents and Chemotherapy, 2010, 54 (6), pp.2323-9. ⟨10.1128/AAC.01511-09⟩
Journal articles pasteur-00835565v1
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Heritability of the human infectious reservoir of malaria parasites.

Yaye Ramatoulaye Lawaly , Anavaj Sakuntabhai , Laurence Marrama , Lassana Konate , Waraphon Phimpraphi
PLoS ONE, 2010, 5 (6), pp.e11358. ⟨10.1371/journal.pone.0011358⟩
Journal articles pasteur-00557029v1
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OPV strains circulation in HIV infected infants after National Immunisation Days in Bangui, Central African Republic.

Alexandre Manirakiza , Emmanuella Picard , Richard Ngbale , Didier Menard , Ionela Gouandjika-Vasilache
BMC Research Notes, 2010, 3, pp.136. ⟨10.1186/1756-0500-3-136⟩
Journal articles pasteur-00540459v1
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History and current status of Plasmodium falciparum antimalarial drug resistance in Madagascar.

Valérie Andriantsoanirina , Didier Ménard , Luciano Tuseo , Rémy Durand
Scandinavian Journal of Infectious Diseases, 2010, 42 (1), pp.22-32. ⟨10.3109/00365540903289670⟩
Journal articles pasteur-00741121v1

High prevalence and fixation of Plasmodium vivax dhfr/dhps mutations related to sulfadoxine/pyrimethamine resistance in French Guiana.

Céline Barnadas , Lise Musset , Eric Legrand , Magali Tichit , Sébastien Briolant
American Journal of Tropical Medicine and Hygiene, 2009, 81 (1), pp.19-22. ⟨10.4269/ajtmh.2009.81.19⟩
Journal articles pasteur-00577267v1
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Plasmodium falciparum drug resistance in Madagascar: facing the spread of unusual pfdhfr and pfmdr-1 haplotypes and the decrease of dihydroartemisinin susceptibility.

Valérie Andriantsoanirina , Arsène Ratsimbasoa , Christiane Bouchier , Martial Jahevitra , Stéphane Rabearimanana
Antimicrobial Agents and Chemotherapy, 2009, 53 (11), pp.4588-97. ⟨10.1128/AAC.00610-09⟩
Journal articles pasteur-00741124v1

Molecular epidemiology of wild poliovirus type 1 circulation in West and Central Africa, from 1997 to 1999, using genotyping with a restriction fragment length polymorphism assay.

Ionela Gouandjika-Vasilache , Cara C Burns , Nicksy Gumede , Sophie Guillot , Didier Ménard
Archiv für die gesamte Virusforschung, 2008, 153 (3), pp.409-16. ⟨10.1007/s00705-007-0001-x⟩
Journal articles pasteur-00319039v1
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Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites.

Marie-Thérèse Ekala , Nimol Khim , Eric Legrand , Milijaona Randrianarivelojosia , Ronan Jambou
Malaria Journal, 2007, 6, pp.164. ⟨10.1186/1475-2875-6-164⟩
Journal articles pasteur-00590983v1

Efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, chloroquine-sulfadoxine-pyrimethamine combination, and amodiaquine-sulfadoxine-pyrimethamine combination in Central African children with noncomplicated malaria.

Didier Ménard , Nestor Madji , Alexandre Manirakiza , Djibrine Djallé , Max Roger Koula
American Journal of Tropical Medicine and Hygiene, 2005, 72 (5), pp.581-5. ⟨10.4269/ajtmh.2005.72.581⟩
Journal articles hal-02560688v1

Evaluation of rapid HIV testing strategies in under equipped laboratories in the Central African Republic

Didier Ménard , Amina Maïro , Marie-Joëlle Mandeng , Placide Doyemet , Thomas d'Aquin Koyazegbe
Journal of Virological Methods, 2005, 126 (1-2), pp.75-80. ⟨10.1016/j.jviromet.2005.01.023⟩
Journal articles hal-02560689v1

HIV epidemic in central african republic: High prevalence rates in both rural and urban areas

Marcelle Diane Matsika-Claquin , Marcel Massanga , Didier Ménard , Jean Mazi-Nzapako , Jean-Pierre Ténegbia
Journal of Medical Virology, 2004, 72 (3), pp.358-362. ⟨10.1002/jmv.20001⟩
Journal articles hal-02560690v1

Advantages of an alternative strategy based on consecutive HIV serological tests for detection of HIV antibodies in Central African Republic

Didier Ménard , Elisa Euridice Mavolomadé , Marie-Joëlle Mandeng , Antoine Talarmin
Journal of Virological Methods, 2003, 111 (2), pp.129-134. ⟨10.1016/s0166-0934(03)00169-1⟩
Journal articles hal-02560692v1

Antimicrobial resistance among uropathogens that cause community-acquired urinary tract infections in Bangui, Central African Republic

Hadiza Hima-Lerible , Didier Ménard , Antoine Talarmin
Journal of Antimicrobial Chemotherapy, 2003, 51 (1), pp.192-194. ⟨10.1093/jac/dkg053⟩
Journal articles hal-02560694v1

Immunohematological Reference Ranges for Adults from the Central African Republic

Didier Ménard , Marie Joelle Mandeng , Mesmin Bem Tothy , Eric Kassa Kelembho , Gérard Gresenguet
Clinical and Diagnostic Laboratory Immunology, 2003, 10 (3), pp.443-445. ⟨10.1128/cdli.10.3.443-445.2003⟩
Journal articles hal-02560693v1

Extrapulmonary and Pulmonary Tuberculosis in Antananarivo (Madagascar): High Clustering Rate in Female Patients

Voahangy Rasolofo Razanamparany , Didier Ménard , Guy Aurégan , Brigitte Gicquel , Suzanne Chanteau
Journal of Clinical Microbiology, 2002, 40 (11), pp.3964-3969. ⟨10.1128/jcm.40.11.3964-3969.2002⟩
Journal articles hal-02560696v1

[Toxoplasmosis, rubella, syphilis, hepatitis B and HIV infection in women being followed for pregnancy in a population on the east coast of New Caledonia ].

Didier Menard
Bulletin de la Société de pathologie exotique , 2001, 94 (5), pp.403-5
Journal articles hal-02560698v1

Transmission of tuberculosis in the prison of Antananarivo (Madagascar)

Voahangy Rasolofo-Razanamparany , Didier Ménard , Mahery Ratsitorahina , Guy Aurégan , Brigitte Gicquel
Research in Microbiology, 2000, 151 (9), pp.785-795. ⟨10.1016/s0923-2508(00)01144-x⟩
Journal articles hal-02560685v1

Prevalence of Mycobacterium bovis in human pulmonary and extra-pulmonary tuberculosis in Madagascar

V Rasolofo-Razanamparany , Didier Menard , T Rasolonavalona , H. Ramarokoto , F. Rakotomanana
International Journal of Tuberculosis and Lung Disease, 1999, 3 (7), pp.632-4
Journal articles hal-02560684v1

Immunoblot applied to the diagnosis of congenital toxoplasmosis

Didier Menard , L. Paris , M. Danis
Pathologie Biologie, 1999, 47 (8), pp.797-804
Journal articles hal-02560686v1

Extra-pulmonary tuberculosis in Antananarivo. Principal localizations and biological diagnosis

Didier Menard , J Pecarrere , F Ramaroson , J Lesbordes , R Andrianirinarisoa
Archives de l'Institut Pasteur de Madagascar, 1995, 62 (1), pp.77-82
Journal articles hal-02560682v1

Study of 3985 female genital smears from the Clinical Biology Center of the Pasteur Institute in Madagascar

F Faibis , J Pecarrere , Didier Menard
Archives de l'Institut Pasteur de Madagascar, 1994, 61 (2), pp.105-7
Journal articles hal-02560681v1