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Synthesis of 1,2,3‐Triazole‐Methyl‐Menadione Derivatives: Evaluation of Electrochemical and Antiparasitic Properties against two Blood‐Dwelling Parasites
Baptiste Dupouy
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Article dans une revue
hal-04892049
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Proteomic Profiling of Antimalarial Plasmodione Using 3‐Benz(o)ylmenadione Affinity‐Based Probes
Ilaria Iacobucci
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Vittoria Monaco
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Agnès Hovasse
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Baptiste Dupouy
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Rodrigue Keumoe
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Article dans une revue
hal-04728204
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3-Benzylmenadiones and their Heteroaromatic Analogues Target the Apicoplast of Apicomplexa Parasites: Synthesis and Bioimaging Studies
Baptiste Dupouy
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Maxime Donzel
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Matthieu Roignant
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Sarah Charital
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Rodrigue Keumoe
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Article dans une revue
hal-04728547
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Regioselective Synthesis of Potential Non-Quinonoid Prodrugs of Plasmodione: Antiparasitic Properties Against Two Hemoglobin-Feeding Parasites and Drug Metabolism Studies
Elena Cesar-Rodo
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Cécile Häberli
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Jean-Marc Strub
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David L Williams
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Article dans une revue
hal-04891107
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Synthesis and anti-Chagas activity profile of a redox-active lead 3benzylmenadione revealed by high-content imaging
Nathan Trometer
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José A. Navarro-Huerta
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hal-04583960
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Click Coupling of Flavylium Dyes with Plasmodione Analogues: Towards New Redox‐Sensitive Pro‐Fluorophores
Baptiste Dupouy
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Article dans une revue
hal-04975248
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Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones
Thibault Gendron
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hal-04583951
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Synthesis and Photochemical Properties of Fluorescent Metabolites Generated from Fluorinated Benzoylmenadiones in Living Cells
Nathan Trometer
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Quentin Chevalier
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Jérémy Pécourneau
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Article dans une revue
hal-04157610
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Efficient Multigram-Scale Synthesis of 7-Substituted 3-Methyltetral-1-ones and 6-Fluoromenadione
Nathan Trometer
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Matthieu Roignant
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Elisabeth Davioud-Charvet
Article dans une revue
hal-03584209
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Evaluation of ferrocenyl-containing gamma-hydroxy-gamma-lactam-derived tetramates as potential antiplasmodials
Maurice Médebielle
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Elisabeth Davioud-Charvet
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European Journal of Medicinal Chemistry, 2022
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hal-03826853
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Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodials
Nicolas Chopin
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Shinya Iikawa
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Article dans une revue
hal-03798632
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The parasitophorous vacuole nutrient channel is critical for drug access in malaria parasites and modulates the artemisinin resistance fitness cost
Paolo Mesén-Ramírez
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hal-03544974
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Bioinspired Photoredox Benzylation of Quinones
Maxime Donzel
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Article dans une revue
hal-03369963
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Recent Advances in Direct C‐H Radical Alkylation of 1,4‐Quinones
Maxime Donzel
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Leandro Cotos Munoz
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Mourad Elhabiri
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hal-03249134
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Magnesium Complexes of Ladanein: A Beneficial Strategy for Stabilizing Polyphenolic Antivirals
Xavier Martin‐benlloch
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Sibylle Haid
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Article dans une revue
hal-03357249
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A role for the succinate dehydrogenase in the mode of action of the redox-active antimalarial drug, plasmodione
Pierre Mounkoro
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hal-03026255
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Plasmodium falciparum Ferredoxin-NADP + Reductase-Catalyzed Redox Cycling of Plasmodione Generates Both Predicted Key Drug Metabolites: Implication for Antimalarial Drug Development
Bogdan Cichocki
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Mindaugas Lesanavičius
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Article dans une revue
hal-03243991
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A Class of Valuable (Pro-)Activity-Based Protein Profiling Probes: Application to the Redox-Active Antiplasmodial Agent, Plasmodione
Bogdan Cichocki
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Article dans une revue
hal-03243960
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Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections
Liwen Feng
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hal-03038691
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Investigating the mode of action of the redox-active antimalarial drug plasmodione using the yeast model
Pierre Mounkoro
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hal-02170571
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Author Correction: Arylmethylamino steroids as antiparasitic agents
Reimar Krieg
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hal-02325972
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Selenium Status in Elderly People: Longevity and Age-Related Diseases
Harry Robberecht
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Article dans une revue
istex
hal-02325568
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Physicochemical Properties Govern the Activity of Potent Antiviral Flavones
Xavier Martin-Benlloch
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hal-02325555
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Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase
Audronė Marozienė
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Alessandro Aliverti
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hal-03038823
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A Mild and Versatile Friedel‐Crafts Methodology for the Diversity‐Oriented Synthesis of Redox‐Active 3‐Benzoylmenadiones with Tuneable Redox Potentials
Leandro Cotos
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Maxime Donzel
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Mourad Elhabiri
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Elisabeth Davioud-Charvet
Article dans une revue
hal-02408960
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AntiMalarial Mode of Action (AMMA) Database: Data Selection, Verification and Chemical Space Analysis
Pavel Sidorov
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Gilles Marcou
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Dragos Horvath
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Article dans une revue
hal-02325960
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Synthesis of plasmodione metabolites and 13C-enriched plasmodione as chemical tools for drug metabolism investigation
Liwen Feng
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Don Antoine Lanfranchi
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Leandro Cotos Munoz
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Elena Cesar Rodo
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Katharina Ehrhardt
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Article dans une revue
hal-02161631
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Iron(iii) coordination properties of ladanein, a flavone lead with a broad-spectrum antiviral activity
Xavier Martin Benlloch
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Mourad Elhabiri
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A Novodomska
Article dans une revue
hal-02161640
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Pharmacomodulation of the antimalarial plasmodione: synthesis of biaryl- and N-arylalkylamine analogues, antimalarial activities and physicochemical properties
Karène Urgin
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Article dans une revue
hal-02177398
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Arylmethylamino steroids as novel antiparasitic agents
R Krieg
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Stephanie Blandin
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S Wittlin
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Article dans une revue
hal-02158243
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A high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase-based mature gametocyte assay
Giulia Siciliano
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Article dans une revue
hal-02161655
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A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs
Mouhamad Jida
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Karène Urgin
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S Mounien
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Article dans une revue
hal-02177403
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QSAR modeling1. and chemical space analysis of antimalarial compounds
Pavel Sidorov
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Article dans une revue
hal-02177404
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In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids
Birgit Viira
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Sandrine Cojean
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Dragos Horvath
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Article dans une revue
hal-03150675
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A Platform of Regioselective Methodologies to Access to Polysubstituted 2-Methyl-1,4-Naphthoquinones Derivatives: Scope and Limitations
Elena Cesar Rodo
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Mouhamad Jida
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Katharina Ehrhardt
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Max Bielitza
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Article dans une revue
istex
hal-03537379
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Redox Polypharmacology as an Emerging Strategy to Combat Malarial Parasites
Pavel Sidorov
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Matthieu Chessé
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Dragos Horvath
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Article dans une revue
istex
hal-03151671
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The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites
Katharina Ehrhardt
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Alice-Anne Goetz
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Tzvetomira Tzanova
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Valentina Gallo
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Article dans une revue
hal-01455775
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Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats
Max Bielitza
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hal-05016881
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Double-drug development against antioxidant enzymes from Plasmodium falciparum
Christophe Biot
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Article dans une revue
mnhn-02867482
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Exploring the trifluoromenadione core as a template to design antimalarial redox-active agents interacting with glutathione reductase
D.A. Lanfranchi
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Article dans une revue
hal-00702812
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A Plant-Derived Flavonoid Inhibits Entry of All HCV Genotypes Into Human Hepatocytes
Sibylle Haid
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Juliane Gentzsch
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Article dans une revue
hal-05017702
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A Glutathione Reductase-Catalyzed Cascade of Redox Reactions to Bioactivate Potent Antimalarial 1,4-Naphthoquinones - A New Strategy to Combat Malarial Parasites
Tobias Müller
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Margit Brückner
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Article dans une revue
hal-03406270
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Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker
Natascha Chavain
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Article dans une revue
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hal-00642006
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The aza-analogues of 1,4-naphthoquinones are potent substrates and inhibitors of plasmodial thioredoxin and glutathione reductases and of human erythrocyte glutathione reductase
Christophe Morin
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Article dans une revue
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hal-02541797
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A Fluoro Analogue of the Menadione Derivative 6-[2‘-(3‘-Methyl)-1‘,4‘-naphthoquinolyl]hexanoic Acid Is a Suicide Substrate of Glutathione Reductase. Crystal Structure of the Alkylated Human Enzyme†
Holger Bauer
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Journal of the American Chemical Society, 2006, The Journal of physical chemistry, 128 (33), pp.10784-10794. ⟨10.1021/ja061155v⟩
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hal-03378811
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Undressing of Phosphine Gold(I) Complexes as Irreversible Inhibitors of Human Disulfide Reductases
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Article dans une revue
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hal-01090379
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Trypanosoma cruzi prolyl oligopeptidase Tc80 is involved in nonphagocytic mammalian cell invasion by trypomastigotes.
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Journal of Biological Chemistry, 2001, 276, pp.47078-47086
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Glutathione-dependent activities of $Trypanosoma\ cruzi$ p52 makes it a new member of the thiol:disulphide oxidoreductase family
Mireille Moutiez
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hal-03637701
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High sensitivity to auxin is a common feature of hairy root
W.H. Shen
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Plant Physiology, 1990, 94, pp.554-560
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Production of indole alkaloids by in vitro root cultures from Catharanthus trichophyllus
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Phytochemistry, 1989, 28 (10), pp.2675-2680
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Cucumopine. A new T-DNA- encoded opine in hairy root and crown-gall
E. Davioud
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Phytochemistry, 1988, 27 (8), pp.2429-2433
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hal-02727299
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Structure and synthesis of cucumopine, a new crown gall and hairy-root opine
E. Davioud
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Heterocycles, 1988, 27 (10), n.p
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