El Chérif Ibrahim

Chargé de Recherche de Classe Normale au CNRS
68 %
Libre accès
50
Documents
Affiliation actuelle
  • Institut de Neurosciences de la Timone (INT)
Identifiants chercheurs

Publications

Publications

A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressants

Grigorios Papageorgiou , El Chérif Ibrahim , Victor Gorgievski , Gabriella Maxson , Evelyn Lozano et al.

Molecular Psychiatry, 2026, Online ahead of print. ⟨10.1038/s41380-026-03491-w⟩

Article dans une revue hal-05517201v1
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A specific GPR56/ADGRG1 splicing isoform is associated with antidepressant response in major depressive disorder

Montaine Lion , El Chérif Ibrahim , Elodie Caccomo-Garcia , Julie Bourret , Guillaume Cinquanta et al.

European Neuropsychopharmacology, 2025, 93, pp.5-14. ⟨10.1016/j.euroneuro.2025.01.001⟩

Article dans une revue hal-04919051v1
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Role of depression, suicide attempt history and childhood trauma in neutrophil-to-lymphocyte ratio dynamics: A 30-week prospective study

M. Lion , M. Muller , E.C. Ibrahim , Wissam El-Hage , A. Lengvenyte et al.

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2025, 136, pp.111227. ⟨10.1016/j.pnpbp.2024.111227⟩

Article dans une revue hal-04858005v1
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Using multiomic integration to improve blood biomarkers of major depressive disorder: a case-control study

Amazigh Mokhtari , El Chérif Ibrahim , Arnaud Gloaguen , Claire-Cécile Barrot , David Cohen et al.

EBioMedicine, 2025, 113, pp.105569. ⟨10.1016/j.ebiom.2025.105569⟩

Article dans une revue hal-04934910v1
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SNORA69 is up-regulated in the lateral habenula of individuals with major depressive disorder

Rixing Lin , Haruka Mitsuhashi , Laura M Fiori , Ryan Denniston , El Cherif Ibrahim et al.

Scientific Reports, 2024, 14, pp.8258. ⟨10.1038/s41598-024-58278-2⟩

Article dans une revue hal-04672660v1
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SNORD90 induces glutamatergic signaling following treatment with monoaminergic antidepressants

Rixing Lin , Aron Kos , Juan Pablo Lopez , Julien Dine , Laura M Fiori et al.

eLife, 2023, 12, pp.e85316. ⟨10.7554/eLife.85316⟩

Article dans une revue hal-04166662v1
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Accelerated aging in bipolar disorders: An exploratory study of six epigenetic clocks

Céline Bourdon , Bruno Etain , Luana Spano , Raoul Belzeaux , Marion Leboyer et al.

Psychiatry Research, 2023, 327, pp.115373. ⟨10.1016/j.psychres.2023.115373⟩

Article dans une revue hal-04181925v2
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The basolateral amygdala-anterior cingulate pathway contributes to depression-like behaviors and comorbidity with chronic pain behaviors in male mice

Léa J. Becker , Clementine Fillinger , Robin Waegaert , Sarah Journée , Pierre Hener et al.

Nature Communications, 2023, 14 (1), ⟨10.1038/s41467-023-37878-y⟩

Article dans une revue hal-04163979v1
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Transcriptomic Studies of Antidepressant Action in Rodent Models of Depression: A First Meta-Analysis

El Chérif Ibrahim , Victor Gorgievski , Pilar Ortiz-Teba , Raoul Belzeaux , Gustavo Turecki et al.

International Journal of Molecular Sciences, 2022, 23, ⟨10.3390/ijms232113543⟩

Article dans une revue hal-03851878v1
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The molecular pathophysiology of mood disorders: From the analysis of single molecular layers to multi-omic integration

Amazigh Mokhtari , Baptiste Porte , Raoul Belzeaux , Bruno Etain , El Cherif Ibrahim et al.

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2022, 116, pp.110520. ⟨10.1016/j.pnpbp.2022.110520⟩

Article dans une revue hal-03568945v1
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Baseline levels of C-reactive protein and proinflammatory cytokines are not associated with early response to amisulpride in patients with First Episode Psychosis: the OPTiMiSE cohort study

Susana Barbosa , Emanuela Martinuzzi , Iris E Sommer , Paola Dazzan , Philip Mcguire et al.

Schizophrenia Bulletin Open, 2021, ⟨10.1093/schizbullopen/sgab017⟩

Article dans une revue hal-03286370v1
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RNA therapeutics for mood disorders: current evidence towards clinical trials

Marguerite Le Marois , Eleni Tzavara , El Chérif Ibrahim , Olivier Blin , Raoul Belzeaux

Expert Opinion on Investigational Drugs, 2021, ⟨10.1080/13543784.2021.1928073⟩

Article dans une revue hal-03361479v1
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Blood cytokines differentiate bipolar disorder and major depressive disorder during a major depressive episode: Initial discovery and independent sample replication

Emanuela Martinuzzi , Susana Barbosa , Philippe Courtet , Emilie Olié , Sébastien Guillaume et al.

Brain, Behavior & Immunity - Health, 2021, 13, pp.100232. ⟨10.1016/j.bbih.2021.100232⟩

Article dans une revue hal-03286374v1
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Immune-Related Genetic Overlap Between Regional Gray Matter Reductions and Psychiatric Symptoms in Adolescents, and Gene-Set Validation in a Translational Model

Lukas Penninck , El Chérif Ibrahim , Eric Artiges , Victor Gorgievski , Sylvane Desrivières et al.

Frontiers in Systems Neuroscience, 2021, 15, ⟨10.3389/fnsys.2021.725413⟩

Article dans une revue hal-03801037v1
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GPR56/ADGRG1 is associated with response to antidepressant treatment

Raoul Belzeaux , Victor Gorgievski , Laura M Fiori , Juan Pablo Lopez , Julien Grenier et al.

Nature Communications, 2020, 11, ⟨10.1038/s41467-020-15423-5⟩

Article dans une revue hal-02530966v1
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Suicide and suicide behaviors: A review of transcriptomics and multiomics studies in psychiatric disorders

Yi Zhou , Pierre-Éric Lutz , El Chérif Ibrahim , Philippe Courtet , Eleni T. Tzavara et al.

Journal of Neuroscience Research, 2020, Neurobiology of Suicidal Behavior, 98 (4), pp.601-615. ⟨10.1002/jnr.24367⟩

Article dans une revue hal-02994964v1
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miR-323a regulates ERBB4 and is involved in depression.

Laura M Fiori , Aron Kos , Rixing Lin , Jean-Francois Théroux , Juan Pablo Lopez et al.

Molecular Psychiatry, 2020, ⟨10.1038/s41380-020-00953-7⟩

Article dans une revue hal-03019942v1
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Deficits in Social Behavior Precede Cognitive Decline in Middle-Aged Mice

Flora Boyer , Florence Jaouen , El Chérif Ibrahim , Eduardo Gascon

Frontiers in Behavioral Neuroscience, 2019, 13, ⟨10.3389/fnbeh.2019.00055⟩

Article dans une revue hal-02080764v1
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Antidepressive effects of targeting ELK-1 signal transduction

Kallia Apazoglou , Séverine Farley , Victor Gorgievski , Raoul Belzeaux , Juan Pablo Lopez et al.

Nature Medicine, 2018, 24 (5), pp.591-597. ⟨10.1038/s41591-018-0011-0⟩

Article dans une revue hal-03365792v2
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Impaired cortico-limbic functional connectivity in schizophrenia patients during emotion processing

Magali Comte , Xavier Y. Zendjidjian , Jennifer T Coull , Aida Cancel , Claire Boutet et al.

Social Cognitive and Affective Neuroscience, 2018, 13 (4), pp.381-390. ⟨10.1093/scan/nsx083⟩

Article dans une revue hal-01801662v1
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Modeling a linkage between blood transcriptional expression and activity in brain regions to infer the phenotype of schizophrenia patients

El Chérif Ibrahim , Vincent Guillemot , Magali Comte , Arthur Tenenhaus , Xavier Yves Zendjidjian et al.

npj Schizophrenia, 2017, 3, pp.27. ⟨10.1038/s41537-017-0027-3⟩

Article dans une revue hal-01583472v1

Treatment of Comorbid Bipolar Disorder Improves Disabilities and Neuropsychological Functioning in DiGeorge Syndrome

Léa C Perret , Marc-Antoine Lodovighi , Odile Perret , El Chérif Ibrahim , Nicole Philip et al.

Journal of Clinical Psychopharmacology, 2017, 37 (6), pp.736 - 738. ⟨10.1097/JCP.0000000000000783⟩

Article dans une revue hal-01909819v1
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Translational Identification of Transcriptional Signatures of Major Depression and Antidepressant Response

Mylène Hervé , Aurélie Bergon , Anne-Marie Le Guisquet , Samuel Leman , Julia-Lou Consoloni et al.

Frontiers in Molecular Neuroscience, 2017, 10, pp.248. ⟨10.3389/fpsyt.2016.00072⟩

Article dans une revue hal-01575031v1
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Biomarker development: current issues and perspectives

Raoul Belzeaux , Julia-Lou Consoloni , El Chérif Ibrahim

Psychoneuroendocrinology, 2017, 78, pp.253-254. ⟨10.1016/j.psyneuen.2017.02.020⟩

Article dans une revue hal-01575043v1
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How to: Measuring blood cytokines in biological psychiatry using commercially available multiplex immunoassays

Raoul Belzeaux , Marie-Noëlle Lefebvre , Anne Lazzari , Tifenn Le Charpentier , Julia-Lou Consoloni et al.

Psychoneuroendocrinology, 2017, 75, pp.72-82. ⟨10.1016/j.psyneuen.2016.10.010⟩

Article dans une revue hal-01575039v1
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Proteasome inhibitors to alleviate aberrant IKBKAP mRNA splicing and low IKAP/hELP1 synthesis in familial dysautonomia

Mylène Hervé , El Chérif Ibrahim

Neurobiology of Disease, 2017, 103, pp.113-122. ⟨10.1016/j.nbd.2017.04.009⟩

Article dans une revue hal-01575049v1

Serotonin transporter gene expression predicts the worsening of suicidal ideation and suicide attempts along a long-term follow-up of a Major Depressive Episode

Julia-Lou Consoloni , El Chérif Ibrahim , Marie-Noëlle Lefebvre , Xavier Zendjidjian , Emilie Olié et al.

European Neuropsychopharmacology, 2017, ⟨10.1016/j.euroneuro.2017.12.015⟩

Article dans une revue hal-01696652v1

Dissociating Bottom-Up and Top-Down Mechanisms in the Cortico-Limbic System during Emotion Processing

Magali Comte , Daniele Schoen , Jennifer T Coull , Emmanuelle Reynaud , Stéphanie Khalfa et al.

Cerebral Cortex, 2016, 26 (1), pp.144-155. ⟨10.1093/cercor/bhu185⟩

Article dans une revue hal-01383987v1
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MicroRNA screening identifies a link between NOVA1 expression and a low level of IKAP in familial dysautonomia

Mylène Hervé , El Chérif Ibrahim

Disease Models & Mechanisms, 2016, 9, pp.899-909. ⟨10.1242/dmm.025841⟩

Article dans une revue hal-01466907v1

Predisposition to treatment response in major depressive episode: A peripheral blood gene coexpression network analysis

Raoul Belzeaux , Chien-Wei Lin , Ying Ding , Aurélie Bergon , El Chérif Ibrahim et al.

Journal of Psychiatric Research, 2016, 81, pp.119-126. ⟨10.1016/j.jpsychires.2016.07.009⟩

Article dans une revue hal-01460127v1
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CX3CR1 is dysregulated in blood and brain from schizophrenia patients

Aurélie Bergon , Raoul A Belzeaux , Magali A Comte , Florence A Pelletier , Mylène A Hervé et al.

Schizophrenia Research, 2015, 168 (1-2), pp.434-443. ⟨10.1016/j.schres.2015.08.010⟩

Article dans une revue istex hal-01575079v1

Mood disorders are associated with a more severe hypovitaminosis D than schizophrenia

Raoul Belzeaux , Laurent Boyer , El Chérif Ibrahim , François Feron , Marion Leboyer et al.

Psychiatry Research, 2015, 229 (1-2), pp.613-616. ⟨10.1016/j.psychres.2015.04.039⟩

Article dans une revue istex hal-02282160v1

Longitudinal monitoring of the serotonin transporter gene expression to assess major depressive episode evolution.

Raoul Belzeaux , Anderson Loundou , Jean-Michel Azorin , Jean Naudin , El Chérif Ibrahim

Neuropsychobiology, 2014, 70 (4), pp.220-7

Article dans une revue hal-01176924v1
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Monitoring candidate gene expression variations before, during and after a first major depressive episode in a 51-year-old man

Raoul Belzeaux , Jean-Michel Azorin , El Chérif Ibrahim

BMC Psychiatry, 2014, 14, pp.73. ⟨10.1186/1471-244X-14-73⟩

Article dans une revue hal-01467882v1
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Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode

Raoul Belzeaux , Aurélie Bergon , Valérie Jeanjean , Béatrice Loriod , Christine Formisano-Tréziny et al.

Translational Psychiatry, 2012, 2, pp.e185. ⟨10.1038/tp.2012.112⟩

Article dans une revue hal-01575056v1

Genome-wide analysis of familial dysautonomia and kinetin target genes with patient olfactory ecto-mesenchymal stem cells.

Nathalie Boone , Aurélie Bergon , Béatrice Loriod , Arnaud Devèze , Catherine Nguyen et al.

Human Mutation, 2012, 33 (3), pp.530-40. ⟨10.1002/humu.22010⟩

Article dans une revue hal-00701177v1
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Clinical variations modulate patterns of gene expression and define blood biomarkers in major depression

Raoul Belzeaux , Christine Formisano-Tréziny , Anderson Loundou , Laurent Boyer , Jean Gabert et al.

Journal of Psychiatric Research, 2010, 44 (16), pp.1205-1213. ⟨10.1016/j.jpsychires.2010.04.011⟩

Article dans une revue hal-04840146v1
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Olfactory Stem Cells, a New Cellular Model for Studying Molecular Mechanisms Underlying Familial Dysautonomia

Nathalie Boone , Béatrice B. Loriod , Aurélie Bergon , Oualid Sbai , Christine Formisano-Tréziny et al.

PLoS ONE, 2010, 5 (12), pp.e15590. ⟨10.1371/journal.pone.0015590⟩

Article dans une revue hal-01612145v1

Weak definition of IKBKAP exon 20 leads to aberrant splicing in familial dysautonomia.

El Chérif Ibrahim , Matthew M Hims , Noam Shomron , Christopher B Burge , Susan A Slaugenhaupt et al.

Human Mutation, 2007, 28 (1), pp.41-53. ⟨10.1002/humu.20401⟩

Article dans une revue istex hal-00320236v1

Therapeutic potential and mechanism of kinetin as a treatment for the human splicing disease familial dysautonomia.

Matthew M Hims , El Chérif Ibrahim , Maire Leyne , James Mull , Lijuan Liu et al.

Journal of Molecular Medicine, 2007, 85 (2), pp.149-61. ⟨10.1007/s00109-006-0137-2⟩

Article dans une revue istex hal-00320234v1

Weak definition of IKBKAP exon 20 leads to aberrant splicing in familial dysautonomia.

El Chérif Ibrahim , Matthew M. Hims , Noam Shomron , Chris B. Burge , Susan A. Slaugenhaupt et al.

Human Mutation, 2006, Epub ahead of Print, Sept 8

Article dans une revue hal-00092919v1

Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers.

El Chérif Ibrahim , Thomas D. Schaal , Klemens J. Hertel , Robin Reed , Tom Maniatis

Proceedings of the National Academy of Sciences of the United States of America, 2005, 102(14), pp.5002-5007

Article dans une revue hal-00092834v1

Analysis of HLA antigen expression in benign and malignant melanocytic lesions reveals that upregulation of HLA-G expression correlates with malignant transformation, high inflammatory infiltration and HLA-A1 genotype.

El Chérif Ibrahim , Selim Aractingi , Yves Allory , Francesco Borrini , Alain Dupuy et al.

International Journal of Cancer, 2004, 108(2), pp.243-250

Article dans une revue hal-00092842v1

Altered pattern of major histocompatibility complex expression in renal carcinoma: tumor-specific expression of the nonclassical human leukocyte antigen-G molecule is restricted to clear cell carcinoma while up-regulation of other major histocompatibility complex antigens is primarily distributed in all subtypes of renal carcinoma.

El Chérif Ibrahim , Yves Allory , Frédéric Commo , Bernard Gattegno , Patrice Callard et al.

American Journal of Pathology, 2003, 162(2), pp.501-508

Article dans une revue hal-00092847v1

Tumor-specific up-regulation of the nonclassical class I HLA-G antigen expression in renal carcinoma.

El Chérif Ibrahim , Nadia Guerra , Marie-José Lacombe , Eric Angevin , Salem Chouaib et al.

Cancer Research, 2001, 61(18), pp.6838-6845

Article dans une revue hal-00092851v1

Heat shock and arsenite induce expression of the nonclassical class I histocompatibility HLA-G gene in tumor cell lines.

El Chérif Ibrahim , Michel Morange , Jean Dausset , Edgardo D. Carosella , Pascale Paul

Cell Stress and Chaperones, 2000, 5(3), pp.207-218

Article dans une revue hal-00092855v1

Leveraging multi-omics integration to uncover childhood traumarelated mechanisms in bipolar disorder

Margot Derouin , Amazigh Mokhtari , El Chérif Ibrahim , Pierre-Eric Lutz , Raoul Belzeaux et al.

JOBIM 2025, Jul 2025, Bordeaux, France. pp.228-229

Communication dans un congrès hal-05344676v1

Mechanisms that determine the correct order of exon joining

El Chérif Ibrahim

Eukaryotic mRNA processing, Cold Spring Harbor, 2003, United States

Communication dans un congrès hal-00093300v1

HLA-G expression in breast carcinoma, melanoma and renal cell carcinoma

El Chérif Ibrahim

13th International Congress of Immunology, Workshop on Tumor Escape, 2001, Sweden

Communication dans un congrès hal-00093352v1