Ellen Van Obberghen-Schilling

43
Documents

Publications

Publications

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Caractérisation quantitative des réseaux de fibronectine dans la matrice extracellulaire tumorale : vers des biomarqueurs pronostiques et prédictifs de réponse à l'immunothérapie

Faisal Jayousi , Xavier Descombes , Emmanuel Bouilhol , Ellen van Obberghen-Schilling , Laure Blanc-Féraud

GRETSI - XXXe Colloque Francophone de Traitement du Signal et des Images, Aug 2025, Strasbourg, France

Communication dans un congrès hal-05398412v1

Statistical Insights into Fibronectin Networks in the Extracellular Matrix

Faisal Jayousi , Xavier Descombes , Emmanuel Bouilhol , Ellen van Obberghen-Schilling , Laure Blanc-Féraud

EMBC 2025, Jul 2025, Copenhagen, Denmark

Communication dans un congrès hal-05071298v1
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Detection and Characterisation of Fibronectin Structures in the Tumour Extracellular Matrix

Faisal Jayousi , Xavier Descombes , Emmanuel Bouilhol , Anne Sudaka , Ellen van Obberghen-Schilling et al.

EUSIPCO 2024 - 32nd European signal processing conference, Aug 2024, Lyon, France

Communication dans un congrès hal-04738081v1
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Optimal Transport vs Many-to-many assignment for Graph Matching

Anca-Ioana Grapa , Laure Blanc-Féraud , Ellen van Obberghen-Schilling , Xavier Descombes

GRETSI 2019 - XXVIIème Colloque francophone de traitement du signal et des images, Aug 2019, Lille, France

Communication dans un congrès hal-02279634v1
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Improving 3D MA-TIRF Reconstruction with Deconvolution and Background Estimation

Emmanuel Soubies , Laure Blanc-Féraud , Sébastien Schaub , Ellen van Obberghen-Schilling

IEEE International Symposium on Biomedical Imaging, Apr 2019, Venise, Italy. ⟨10.1109/ISBI.2019.8759103⟩

Communication dans un congrès hal-02017862v1
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Classification of the fibronectin variants with curvelets

Anca-Ioana Grapa , Raphael Meunier , Laure Blanc-Féraud , Georgios Efthymiou , Sébastien Schaub et al.

ISBI 2018 - IEEE 15th International Symposium on Biomedical Imaging, Apr 2018, Washington, DC, United States. pp. 930-933, ⟨10.1109/ISBI.2018.8363723⟩

Communication dans un congrès hal-01868726v1
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A Framework for Multi-angle Tirf Microscope Calibration

Emmanuel Soubies , Sébastien Schaub , Agata Radwanska , Ellen van Obberghen-Schilling , Laure Blanc-Féraud et al.

ISBI - International Symposium on Biomedical Imaging, Apr 2016, Prague, Czech Republic. pp.4, ⟨10.1109/ISBI.2016.7493355⟩

Communication dans un congrès hal-01257736v1
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Coalescent RNA-localizing and transcriptional activities of SAM68 modulate adhesion and subendothelial basement membrane assembly

Zeinab Rekad , Michaël Ruff , Agata Radwanska , Dominique Grall , Delphine Ciais et al.

eLife, 2023, 12, pp.e85165. ⟨10.7554/elife.85165⟩

Article dans une revue hal-04225341v1
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A positive feedback loop driven by fibronectin and IL-1β sustains the inflammatory microenvironment in breast cancer

Gurcan Tunali , Hamdullah Yanik , Suleyman Can Ozturk , Secil Demirkol-Canli , Georgios Efthymiou et al.

Breast Cancer Research, 2023, 25 (1), pp.27. ⟨10.1186/s13058-023-01629-0⟩

Article dans une revue hal-04042894v1
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A spatial statistical framework for the parametric study of fiber networks: application to fibronectin deposition by normal and activated fibroblasts

Anca-Ioana Grapa , Georgios Efthymiou , Ellen van Obberghen-Schilling , Laure Blanc-Féraud , Xavier Descombes

Biological Imaging, In press, ⟨10.1017/S2633903X23000247⟩

Article dans une revue hal-04320315v2
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The Alternative Matrisome: alternative splicing of ECM proteins in development, homeostasis and tumor progression

Zeinab Rekad , Valerio Izzi , Rijuta Lamba , Delphine Ciais , Ellen van Obberghen-Schilling

Matrix Biology, 2022, pp.S0945-053X(22)00069-5. ⟨10.1016/j.matbio.2022.05.003⟩

Article dans une revue inserm-03677713v1

The role of the tumor matrix environment in progression of head and neck cancer

Ellen van Obberghen-Schilling , Angélique Saint

Current Opinion in Oncology, 2021, 33 (3), pp.168-174. ⟨10.1097/CCO.0000000000000730⟩

Article dans une revue hal-03356726v1
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High Dimensional Imaging Mass Cytometry Panel to Visualize the Tumor Immune Microenvironment Contexture

Roxane Elaldi , Patrice Hemon , Luciana Petti , Estelle Cosson , Belinda Desrues et al.

Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.666233⟩

Article dans une revue hal-03368202v1
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Fibronectin Extra Domains tune cellular responses and confer topographically distinct features to fibril networks

Georgios Efthymiou , Agata Radwanska , Anca-Ioana Grapa , Stéphanie Beghelli-de La Forest Divonne , Dominique Grall et al.

Journal of Cell Science, 2021, ⟨10.1242/jcs.252957⟩

Article dans une revue hal-03282792v1
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Shaping Up the Tumor Microenvironment With Cellular Fibronectin

Georgios Efthymiou , Angélique Saint , Michaël Ruff , Zeinab Rekad , Delphine Ciais et al.

Frontiers in Oncology, 2020, 10, pp.641. ⟨10.3389/fonc.2020.00641⟩

Article dans une revue (article de synthèse) hal-02890933v1
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Tenascin-C orchestrates an immune suppressive tumor microenvironment in oral squamous cell carcinoma

Caroline Spenlé , Thomas Loustau , Devadarssen Murdamoothoo , William Erne , Stéphanie Beghelli-de La Forest Divonne et al.

Cancer Immunology Research, 2020, 8 (9), pp.1122-1138. ⟨10.1158/2326-6066.CIR-20-0074⟩

Article dans une revue hal-02902040v1
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The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again

Paul Hofman , Nicholas Ayache , Pascal Barbry , Michel Barlaud , Audrey Bel et al.

Cancers, 2019, 11 (2), pp.1-11. ⟨10.3390/cancers11020250⟩

Article dans une revue hal-02045442v1

Nanometric axial resolution of fibronectin assembly units achieved with an efficient reconstruction approach for multi-angle-TIRF microscopy

Emmanuel Soubies , Agata Radwanska , Dominique Grall , Laure Blanc-Féraud , Ellen van Obberghen-Schilling et al.

Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-018-36119-3⟩

Article dans une revue hal-02017844v1
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Fibronectin-guided migration of carcinoma collectives

Sandeep Gopal , Laurence Veracini , Dominique Grall , Catherine Butori , Sébastien Schaub et al.

Nature Communications, 2017, 8, pp.14105. ⟨10.1038/ncomms14105⟩

Article dans une revue hal-01783964v1
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Counterbalancing anti-adhesive effects of Tenascin-C through fibronectin expression in endothelial cells.

Agata Radwanska , Dominique Grall , Sébastien Schaub , Stéphanie Beghelli-de la Forest Divonne , Forest Divonne et al.

Scientific Reports, 2017, 7 (1), pp.12762. ⟨10.1038/s41598-017-13008-9⟩

Article dans une revue inserm-01617198v1
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Tenascin-C Orchestrates Glioblastoma Angiogenesis by Modulation of Pro- and Anti-angiogenic Signaling

Tristan Rupp , Benoit Langlois , Maria Koczorowska , Agata Radwanska , Zhen Sun et al.

Cell Reports, 2016, 17 (10), pp.2607-2619. ⟨10.1016/j.celrep.2016.11.012⟩

Article dans une revue hal-03599259v1
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A Positive Feed-forward Loop Associating EGR1 and PDGFA Promotes Proliferation and Self-renewal in Glioblastoma Stem Cells

Nathalie Sakakini , Laurent Turchi , Aurélie Bergon , Hélène Holota , Samah Rekima et al.

Journal of Biological Chemistry, 2016, 291 (20), pp.10684-10699. ⟨10.1074/jbc.M116.720698⟩

Article dans une revue hal-01460121v1

Integrating genomics in head and neck cancer treatment: Promises and pitfalls.

Juliette Thariat , Stéphane Vignot , Ariane Lapierre , Alexander T Falk , Joel Guigay et al.

Critical Reviews in Oncology/Hematology, 2015, 95 (3), pp.397-406

Article dans une revue hal-01252906v1

Tumorigenic Potential of miR-18A* in Glioma Initiating Cells Requires NOTCH-1 Signaling.

Laurent Turchi , David N Debruyne , Fabien Almairac , Virginie Virolle , Mohamed Fareh et al.

Stem Cells / Stem Cells (Miamisburg), 2013, epub ahead of print. ⟨10.1002/stem.1373⟩

Article dans une revue hal-00811588v1

Fibronectin expression in glioblastomas promotes cell cohesion, collective invasion of basement membrane in vitro and orthotopic tumor growth in mice.

E. Serres , F. Debarbieux , F. Stanchi , L. Maggiorella , D. Grall et al.

Oncogene, 2013, epub ahead of print. ⟨10.1038/onc.2013.305⟩

Article dans une revue hal-00862133v1

Contrasted outcomes to gefitinib on tumoral IGF1R expression in head and neck cancer patients receiving postoperative chemoradiation (GORTEC trial 2004-02).

Juliette Thariat , René-Jean Bensadoun , Marie-Christine Etienne-Grimaldi , Dominique Grall , Frédérique Penault-Llorca et al.

Clinical Cancer Research, 2012, 18 (18), pp.5123-33. ⟨10.1158/1078-0432.CCR-12-1518⟩

Article dans une revue hal-00770510v1

Epidermal growth factor receptor protein detection in head and neck cancer patients: a many-faceted picture.

Juliette Thariat , Marie-Christine Etienne-Grimaldi , Dominique Grall , René-Jean Bensadoun , Anne Cayre et al.

Clinical Cancer Research, 2012, 18 (5), pp.1313-22. ⟨10.1158/1078-0432.CCR-11-2339⟩

Article dans une revue hal-00770516v1

Fibronectin and tenascin-C: accomplices in vascular morphogenesis during development and tumor growth.

Ellen van Obberghen-Schilling , Richard P Tucker , Falk Saupe , Isabelle Gasser , Botond Cseh et al.

Int J Dev Biol, 2011, 55 (4-5), pp.511-25. ⟨10.1387/ijdb.103243eo⟩

Article dans une revue hal-00638899v1

Autocrine fibronectin directs matrix assembly and crosstalk between cell-matrix and cell-cell adhesion in vascular endothelial cells.

Botond Cseh , Samantha Fernandez-Sauze , Dominique Grall , Sébastien Schaub , Eszter Doma et al.

Journal of Cell Science, 2010, 123 (Pt 22), pp.3989-99. ⟨10.1242/jcs.073346⟩

Article dans une revue hal-00533759v1

Regulation of fibronectin matrix assembly and capillary morphogenesis in endothelial cells by Rho family GTPases.

Samantha Fernandez-Sauze , Dominique Grall , Botond Cseh , Ellen van Obberghen-Schilling

Experimental Cell Research, 2009, 315 (12), pp.2092-104. ⟨10.1016/j.yexcr.2009.03.017⟩

Article dans une revue istex hal-00435697v1

Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation.

Fabio Stanchi , Carsten Grashoff , Carine Flore Nguemeni Yonga , Dominique Grall , Reinhard Fässler et al.

Journal of Cell Science, 2009, 122 (Pt 11), pp.1800-11. ⟨10.1242/jcs.044602⟩

Article dans une revue hal-00435696v1

Overexpression of cortactin in head and neck squamous cell carcinomas can be uncoupled from augmented EGF receptor expression.

Ivana Fantozzi , Dominique Grall , Sebastien Cagnol , Fabio Stanchi , Anne Sudaka et al.

Langenbeck's Archives of Surgery, 2008, pp.1-11. ⟨10.1080/02841860802089801⟩

Article dans une revue hal-00319334v1

Prognostic significance of cortactin levels in head and neck squamous cell carcinoma: comparison with epidermal growth factor receptor status.

P. Hofman , C. Butori , K. Havet , Véronique Hofman , E. Selva et al.

British Journal of Cancer, 2008, 98 (5), pp.956-64. ⟨10.1038/sj.bjc.6604245⟩

Article dans une revue hal-00319713v1

Pituicyte stellation is prevented by RhoA-or Cdc42-dependent actin polymerization.

Lia Rosso , Patricia M Pierson , Claire Golfier , Brigitta Peteri-Brunbäck , Christophe Deroanne et al.

Cellular and Molecular Neurobiology, 2007, 27 (6), pp.791-804. ⟨10.1007/s10571-007-9176-7⟩

Article dans une revue hal-00319390v1

Regulation of cell-matrix adhesion dynamics and Rac-1 by integrin linked kinase.

Etienne Boulter , Dominique Grall , Sébastien Cagnol , Ellen van Obberghen-Schilling

FASEB Journal, 2006, 20 (9), pp.1489-91. ⟨10.1096/fj.05-4579fje⟩

Article dans une revue hal-00322033v1

Prolonged activation of ERK1,2 induces FADD-independent caspase 8 activation and cell death.

S. Cagnol , E. van Obberghen-Schilling , J.-C. Chambard

Apoptosis, 2006, 11 (3), pp.337-46. ⟨10.1007/s10495-006-4065-y⟩

Article dans une revue istex hal-00322043v1

Transforming growth factor beta induces rosettes of podosomes in primary aortic endothelial cells.

Christine Varon , Florence Tatin , Violaine Moreau , Ellen van Obberghen-Schilling , Samantha Fernandez-Sauze et al.

Molecular and Cellular Biology, 2006, 26 (9), pp.3582-94. ⟨10.1128/MCB.26.9.3582-3594.2006⟩

Article dans une revue hal-00322039v1

Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.

Sylvie Maubant , Dominique Saint-Dizier , Morgane Boutillon , Francoise Perron-Sierra , Patrick J Casara et al.

Blood, 2006, 108 (9), pp.3035-44. ⟨10.1182/blood-2006-05-023580⟩

Article dans une revue hal-00322030v1

Integrin-linked kinase and its partners: a modular platform regulating cell-matrix adhesion dynamics and cytoskeletal organization.

Etienne Boulter , Ellen van Obberghen-Schilling

European Journal of Cell Biology, 2006, 85 (3-4), pp.255-63. ⟨10.1016/j.ejcb.2005.09.002⟩

Article dans une revue istex hal-00322040v1

ILK is required for the assembly of matrix-forming adhesions and capillary morphogenesis in endothelial cells.

Valérie Vouret-Craviari , Etienne Boulter , Dominique Grall , Cédric Matthews , Ellen van Obberghen-Schilling

Journal of Cell Science, 2004, 117 (Pt 19), pp.4559-69. ⟨10.1242/jcs.01331⟩

Article dans une revue hal-00322356v1

Adhesion-dependent control of Akt/protein kinase B occurs at multiple levels.

Maude Le Gall , Jean-Claude Chambard , Dominique Grall , Ellen van Obberghen-Schilling

Journal of Cellular Physiology, 2003, 196 (1), pp.98-104. ⟨10.1002/jcp.10276⟩

Article dans une revue istex hal-00322360v1

Modulation of Rho GTPase activity in endothelial cells by selective proteinase-activated receptor (PAR) agonists.

V. Vouret-Craviari , D. Grall , E. van Obberghen-Schilling

Journal of Thrombosis and Haemostasis, 2003, 1 (5), pp.1103-11

Article dans une revue hal-00322357v1

Differential activation of p44mapk (ERK1) by alpha-thrombin and thrombin-receptor peptide agonist.

V. Vouret-Craviari , Ellen van Obberghen-Schilling , Jean-Claude Scimeca , Emmanuel van Obberghen , J. Pouyssegur

Biochemical Journal, 1993, 289 ( Pt 1), pp.209-14

Article dans une revue hal-02109559v1