Eric Hajduch

28
Documents

Publications

Publications

Inverse relationship between circulating sphingosine-1-phosphate and precursor species and coronary artery calcification score in type 2 diabetes

Wilfried Le Goff , Olivier Bourron , Clément Materne , Sophie Galier , Franck Phan et al.
Cardiovascular Diabetology, 2025, 24 (1), pp.85. ⟨10.1186/s12933-025-02624-9⟩
Article dans une revue hal-04975939 v1

Sphingosine‐1‐phosphate signalling in the heart: exploring emerging perspectives in cardiopathology

Franck Phan , Olivier Bourron , Fabienne Foufelle , Hervé Le Stunff , Eric Hajduch
FEBS Letters, 2024, Online ahead of print. ⟨10.1002/1873-3468.14973⟩
Article dans une revue hal-04726365 v1
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Editorial: The Role of Sphingolipid Metabolism in the Development of Type 2 Diabetes and Obesity

Agnieszka Blachnio-Zabielska , Eric Hajduch , Hervé Le Stunff
Frontiers in Endocrinology, 2022, 12, pp.835751. ⟨10.3389/fendo.2021.835751⟩
Article dans une revue hal-03543478 v1
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The Reciprocal Relationship between LDL Metabolism and Type 2 Diabetes Mellitus

Isabella Bonilha , Eric Hajduch , Beatriz Luchiari , Wilson Nadruz , Wilfried Le Goff et al.
Metabolites, 2021, 11 (12), pp.807. ⟨10.3390/metabo11120807⟩
Article dans une revue hal-03467601 v1
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Roles of Ceramides in Non-Alcoholic Fatty Liver Disease

Eric Hajduch , Floriane Lachkar , Pascal Ferré , Fabienne Foufelle
Journal of Clinical Medicine, 2021, 10 (4), pp.792. ⟨10.3390/jcm10040792⟩
Article dans une revue hal-03163597 v1
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Sphingolipid Metabolism and Signaling in Skeletal Muscle: From Physiology to Physiopathology

Sophie Tan-Chen , Jeanne Guitton , Olivier Bourron , Hervé Le Stunff , Eric Hajduch
Frontiers in Endocrinology, 2020, 11, pp.491. ⟨10.3389/fendo.2020.00491⟩
Article dans une revue hal-02939128 v1
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Céramides, acteurs cruciaux dans le développement de l’insulino-résistance et du diabète de type 2

Sophie Tan-Chen , Olivier Bourron , Eric Hajduch
Médecine/Sciences, 2020, 36 (5), pp.497-503. ⟨10.1051/medsci/2020091⟩
Article dans une revue hal-02866498 v1
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Dihydroceramides in Triglyceride-Enriched VLDL Are Associated with Nonalcoholic Fatty Liver Disease Severity in Type 2 Diabetes

Aurélie Carlier , Franck Phan , Anaïs Szpigel , Eric Hajduch , Joe-Elie Salem et al.
Cell Reports Medicine, 2020, 1 (9), pp.100154. ⟨10.1016/j.xcrm.2020.100154⟩
Article dans une revue hal-03099637 v1
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Sphingosine-1-Phosphate Metabolism in the Regulation of Obesity/Type 2 Diabetes

Jeanne Guitton , Cécile L Bandet , Mohamed Mariko , Sophie Tan-Chen , Olivier Bourron et al.
Cells, 2020, 9 (7), pp.1682. ⟨10.3390/cells9071682⟩
Article dans une revue hal-02902856 v1
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Sphingolipid Metabolism: New Insight into Ceramide-Induced Lipotoxicity in Muscle Cells

Cécile L Bandet , Sophie Tan-Chen , Olivier Bourron , Hervé Le Stunff , Eric Hajduch
International Journal of Molecular Sciences, 2019, Ceramide, 20 (3), pp.479. ⟨10.3390/ijms20030479⟩
Article dans une revue hal-02094670 v1
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Ceramide Transporter CERT Is Involved in Muscle Insulin Signaling Defects Under Lipotoxic Conditions

Cécile L Bandet , Rana Mahfouz , Julien Véret , Athanassia Sotiropoulos , Maxime Poirier et al.
Diabetes, 2018, 67 (7), pp.1258-1271. ⟨10.2337/db17-0901⟩
Article dans une revue hal-02450782 v1

Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes

Anaïs Szpigel , Isabelle Hainault , Aurélie Carlier , Nicolas Venteclef , Anne-Françoise Batto et al.
Diabetologia, 2018, 61 (2), pp.399-412. ⟨10.1007/s00125-017-4462-5⟩
Article dans une revue hal-02450833 v1
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Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances β-cell function of obese Zucker rats

Mélanie Campana , Lara Bellini , Claude Rouch , Latif Rachdi , Nicolas Coant et al.
Molecular metabolism, 2018, 8, pp.23-36. ⟨10.1016/j.molmet.2017.10.013⟩
Article dans une revue hal-02450789 v1

Short Term Palmitate Supply Impairs Intestinal Insulin Signaling via Ceramide Production

Thi Thu Trang Tran , Bárbara Graziela Postal , Sylvie Demignot , Agnès Ribeiro , Céline Osinski et al.
Journal of Biological Chemistry, 2016, 291 (31), pp.16328-16338. ⟨10.1074/jbc.M115.709626⟩
Article dans une revue hal-01369518 v1

Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE*

Rima Hage Hassan , Ana Catarina Pacheco de Sousa , Rana Mahfouz , Isabelle Hainault , Agnieszka Blachnio-Zabielska et al.
Journal of Biological Chemistry, 2016, 291 (6), pp.3019-3029. ⟨10.1074/jbc.M115.686949⟩
Article dans une revue hal-01340226 v1

Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes

Lara Bellini , Mélanie Campana , Rana Mahfouz , Aurélie Carlier , Julien Véret et al.
Expert Opinion on Therapeutic Targets, 2015, 19 (8), pp.1037-1050. ⟨10.1517/14728222.2015.1028359⟩
Article dans une revue hal-02450878 v1
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Enhanced Insulin Sensitivity Associated with Provision of Mono and Polyunsaturated Fatty Acids in Skeletal Muscle Cells Involves Counter Modulation of PP2A

Francesca Nardi , Christopher Lipina , David Magill , Rima Hage Hassan , Eric Hajduch et al.
PLoS ONE, 2014, 9 (3), pp.e92255. ⟨10.1371/journal.pone.0092255⟩
Article dans une revue hal-01368348 v1
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Characterising the Inhibitory Actions of Ceramide upon Insulin Signaling in Different Skeletal Muscle Cell Models: A Mechanistic Insight

Rana Mahfouz , Rhéa Khoury , Agnieszka Blachnio-Zabielska , Sophie Turban , Nicolas Loiseau et al.
PLoS ONE, 2014, 9 (7), pp.e101865. ⟨10.1371/journal.pone.0101865⟩
Article dans une revue hal-01366387 v1

Defect of insulin signal in peripheral tissues: Important role of ceramide

Rima Hage Hassan , Bourron Olivier , Eric Hajduch
World Journal of Diabetes, 2014, 5 (3), pp.244. ⟨10.4239/wjd.v5.i3.244⟩
Article dans une revue hal-02450858 v1

The lipoatrophic caveolin-1 deficient mouse model reveals autophagy in mature adipocytes

Soazig Le Lay , Nolwenn Briand , Cedric M Blouin , Danielle Chateau , Cécilia Prado et al.
Autophagy, 2014, 6 (6), pp.754-763. ⟨10.4161/auto.6.6.12574⟩
Article dans une revue hal-02450948 v1

New insights into ER stress-induced insulin resistance

Mélissa Flamment , Eric Hajduch , Pascal Ferré , Fabienne Foufelle
Trends in Endocrinology and Metabolism = Trends in Endocrinology & Metabolism , 2012, 23 (8), pp.381-390. ⟨10.1016/j.tem.2012.06.003⟩
Article dans une revue istex hal-02450915 v1

Protein kinase C isoforms: Mediators of reactive lipid metabolites in the development of insulin resistance

Sophie Turban , Eric Hajduch
FEBS Letters, 2011, 585 (2), pp.269-274. ⟨10.1016/j.febslet.2010.12.022⟩
Article dans une revue hal-02450938 v1

Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects

Cedric M Blouin , Soazig Le Lay , Anita Eberl , Harald Köfeler , Ida Chiara Guerrera et al.
Journal of Lipid Research, 2010, 51 (5), pp.945-956. ⟨10.1194/jlr.M001016⟩
Article dans une revue hal-02450951 v1

Plasma Membrane Subdomain Compartmentalization Contributes to Distinct Mechanisms of Ceramide Action on Insulin Signaling

Cédric M Blouin , Cécilia Prado , Karen Takane K , Françoise Lasnier , Adolfo Garcia-Ocana et al.
Diabetes, 2010, 59 (3), pp.600-610. ⟨10.2337/db09-0897⟩
Article dans une revue hal-02451037 v1

Expression and modulation of TUB by insulin and thyroid hormone in primary rat and murine 3T3-L1 adipocytes

Clare Stretton , Gary Litherland , Audrey Moynihan , Eric Hajduch , Harinder Hundal
Biochemical and Biophysical Research Communications, 2009, 390 (4), pp.1328-1333. ⟨10.1016/j.bbrc.2009.10.147⟩
Article dans une revue istex hal-02450961 v1

Filling up adipocytes with lipids. Lessons from caveolin-1 deficiency

Soazig Le Lay , Cédric M. Blouin , Eric Hajduch , Isabelle Dugail
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2009, 1791 (6), pp.514-518. ⟨10.1016/j.bbalip.2008.10.008⟩
Article dans une revue istex hal-02450963 v1
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Targeting of PKC{zeta} and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signaling by ceramide

Eric Hajduch , Sophie Turban , Xavier Le Liepvre , Soazig Le Lay , Christopher Lipina et al.
Biochemical Journal, 2008, 410 (2), pp.369-379. ⟨10.1042/BJ20070936⟩
Article dans une revue hal-00478845 v1

Regulated association of caveolins to lipid droplets during differentiation of 3T3-L1 adipocytes.

Cédric M. Blouin , Soazig Le Lay , Françoise Lasnier , Isabelle Dugail , Eric Hajduch
Biochemical and biophysical research communications, 2008, 376 (2), pp.331-5. ⟨10.1016/j.bbrc.2008.08.154⟩
Article dans une revue istex hal-03328699 v1