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Lieu de travail : Laboratoire Structure & Dynamique par Résonance Magnétique (LSDRM) IRAMIS/NIMBE, UMR CEA/CNRS 3685 CEA Saclay 91191 Gif sur Yvette Activité scientifique : RMN et IRM du xénon hyperpolarisé pour l'étude : - d'échantillons cellulaires - de biosondes - de matériaux poreux Developpement de pompage optique de gaz rare (mobile) Microfluidique pour la RMN en flux


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Are the physical properties of Xe@cryptophane complexes easily predictable? the case of $syn$ and $anti$ tris-$aza$-cryptophanes

Martin Doll , Patrick Berthault , Estelle Léonce , Céline Boutin , Thierry Buffeteau
Journal of Organic Chemistry, 2021, 86 (11), pp.7648-7658. ⟨10.1021/acs.joc.1c00701⟩
Journal articles cea-03250187v1
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$^{129}$Xe Ultrafast Z-spectroscopy enables micromolar detection of biosensors on a 1T benchtop spectrometer

Kévin Chighine , Estelle Léonce , Céline Boutin , Hervé Desvaux , Patrick Berthault
Magnetic Resonance, 2021, 2, pp.409-420. ⟨10.5194/mr-2-409-2021⟩
Journal articles cea-03182749v2

Synthesis of Cryptophane-223-Type Derivatives with Dual Functionalization

Orsola Baydoun , Nicolas de Rycke , Estelle Léonce , Céline Boutin , Patrick Berthault
Journal of Organic Chemistry, 2019, 84, pp.9127-9137. ⟨10.1021/acs.joc.9b01093⟩
Journal articles cea-02183121v1
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Enantiopure [Cs$^+$/Xe$\subset$Cryptophane]$\subset$Fe$^{II}$$_4$L$_4$ Hierarchical Superstructures

Dawei Zhang , Tanya K. Ronson , Jake L. Greenfield , Thierry Brotin , Patrick Berthault
Journal of the American Chemical Society, 2019, 141 (20), pp.8339-8345. ⟨10.1021/jacs.9b02866⟩
Journal articles cea-02117134v1
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Bimodal detection of proteins by $^{129}$Xe NMR and fluorescence spectroscopy

Emilie Mari , Yasmina Bousmah , Céline Boutin , Estelle Léonce , Gaëlle Milanole
ChemBioChem, 2019, 20, pp.1450-1457. ⟨10.1002/cbic.201800802⟩
Journal articles cea-01988479v1
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Synthesis of Cryptophane-B. Crystal Structure and Study of its Complex with Xenon.

Thierry Brotin , Erwann Jeanneau , Patrick Berthault , Estelle Léonce , Delphine Pitrat
Journal of Organic Chemistry, 2018, 83, pp.14465-14471. ⟨10.1021/acs.joc.8b02246⟩
Journal articles cea-01922217v1
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Accurate pH sensing via hyperpolarized $^{129}$Xe NMR

Patrick Berthault , Estelle Léonce , Jean-Pierre Dognon , Delphine Pitrat , Jean-Christophe Mulatier
Chemistry - A European Journal, inPress, 24, pp.6534-6537. ⟨10.1002/chem.201800900⟩
Journal articles cea-01720386v1
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Unsaturated cryptophanes: toward dual PHIP/hyperpolarised xenon sensors

Gaspard Huber , Estelle Léonce , Orsola Baydoun , Nicolas de Rycke , Thierry Brotin
Magnetic Resonance in Chemistry, inPress, 56, pp.672-678. ⟨10.1002/mrc.4691⟩
Journal articles cea-01660523v1
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Bimodal Fluorescence/{129}Xe NMR Probe for Molecular Imaging and Biological Inhibition of EGFR in Non-Small Cell Lung Cancer

Gaëlle Milanole , Bo Gao , Audrey Paoletti , Grégory Pieters , Christophe Dugave
Bioorganic and Medicinal Chemistry, 2017, 25, pp.6653-6660. ⟨10.1016/j.bmc.2017.11.002⟩
Journal articles cea-01630103v1
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Role of the Methoxy Groups in Cryptophanes for Complexation of Xenon. Conformational Selection Evidenced by 129 Xe-1 H NMR SPINOE Experiments

Patrick Berthault , Céline Boutin , Estelle Léonce , Erwann Jeanneau , Thierry Brotin
ChemPhysChem, 2017, 18, pp.1561-1568. ⟨10.1002/cphc.201700266⟩
Journal articles cea-01510320v1
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Spin-Exchange optical pumping in a van

Christian Chauvin , Louis Liagre , Céline Boutin , Emilie Mari , Estelle Léonce
Review of Scientific Instruments, 2016, 87, pp.016105. ⟨10.1063/1.4940928⟩
Journal articles cea-01264746v1
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A doubly responsive probe for the detection of Cys4-tagged proteins

Naoko Kotera , Emmanuelle Dubost , Gaëlle Milanole , Eric Doris , Edmond Gravel
Chemical Communications, 2015, 51, pp.11482-11484. ⟨10.1039/C5CC04721H⟩
Journal articles hal-01187782v1
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Rim-functionalized cryptophane-111 derivatives via heterocapping, and their xenon complexes

Akil I. Joseph , Gracia El-Ayle , Céline Boutin , Estelle Léonce , Patrick Berthault
Chemical Communications, 2014, 50, pp.15905. ⟨10.1039/C4CC08001G⟩
Journal articles hal-01157474v1

Smart Detection of Toxic Metal Ions, Pb2+ and Cd2+, Using a 129Xe NMR-Based Sensor

Nawal Tassali , Naoko Kotera , Céline Boutin , Estelle Léonce , Yves Boulard
Analytical and Bioanalytical Chemistry, 2014, 86 (3), pp.1783-1788. ⟨10.1021/ac403669p⟩
Journal articles hal-01117441v1

Understanding a Host–Guest Model System through 129Xe NMR Spectroscopic Experiments and Theoretical Studies†

Emmanuelle Dubost , Jean-Pierre Dognon , Bernard Rousseau , Gaëlle Milanole , Christophe Dugave
Angewandte Chemie International Edition, 2014, 53, pp.9837-9840. ⟨10.1002/anie.201405349⟩
Journal articles hal-01157472v1

Ultrafast Z-Spectroscopy for 129 Xe NMR-Based Sensors

Céline Boutin , Estelle Léonce , Thierry Brotin , Alexej Jerschow , Patrick Berthault
Journal of Physical Chemistry Letters, 2013, 4 (23), pp.4172 - 4176. ⟨10.1021/jz402261h⟩
Journal articles hal-01896791v1

A Sensitive Zinc-Activated 129Xe MRI Probe

Naoko Kotera , Nawal Tassali , Estelle Léonce , Céline Boutin , Patrick Berthault
Angewandte Chemie International Edition, 2012, 51 (17), pp.4100-4103. ⟨10.1002/anie.201109194⟩
Journal articles hal-01117150v1

Toward new cryptophane analogs: synthesis and encapsulation properties of an unprecedented water-soluble azacryptophane

Rajaa Benchouaia , Martin Doll , Patrick Berthault , Kevin Chighine , Estelle Léonce
3rd French Supramolecular Chemistry Congress Supr@Paris2024, May 2024, Paris, France
Conference papers hal-04584742v1
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$^{129}$Xe NMR-based biosensing on a benchtop spectrometer

Kévin Chighine , Estelle Léonce , Céline Boutin , Hervé Desvaux , Patrick Berthault
Compact NMR Conference II, CEISAM research institute, Oct 2021, Nantes (Virtual event), France
Conference papers cea-03375713v1
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Following the growth of Saccharomyces Cerevisiae in standard culture conditions using hyperpolarized $^{129}$Xe NMR

Céline Boutin , Estelle Léonce , Patrick Berthault , Guillaume Carret
EUROMAR 2018, Jul 2018, Nantes, France
Conference papers cea-02339659v1

Understanding a Host-guest model system through 129Xe NMR experiments and theoretical chemistry

Jean-Pierre Dognon , Emmanuelle Dubost , Bernard Rousseau , Gaëlle Milanole , Christophe Dugave
GERM 2015, May 2015, Sète, France
Conference papers cea-02356628v1

New developments related to fast and multiplexed detection of 129Xe NMR biosensor

Patrick Berthault , Céline Boutin , Guillaume Carret , Jean-Pierre Dognon , Estelle Léonce
International Symposium XeMAT 2015, Sep 2015, Dresden, Germany
Conference papers cea-02352715v1

Dernières avancées sur l'utilisation du xénon polarisé comme biosonde

Céline Boutin , Estelle Léonce , Emilie Mari , Guillaume Carret , Emmanuelle Dubost
GERM 2014 (Groupe d’Etude de Résonance Magnétique), Jun 2014, Biarritz, France
Conference papers cea-02361804v1