Etienne B. Blanc

Maitre de Conférence, HC, HDR, Biochimie-Toxicologie, Université Paris Cité

Documents

Affiliations actuelles

Université Paris Cité (UPCité)
Université Sorbonne Paris Cité (USPC)
Université Paris Descartes - Paris 5 (UPD5)
INSERM (U1124)
INSERM UMR S-747
Health and Functional Exposomics (HealthFex | U1124)
Institut de recherche en santé, environnement et travail (Irset)
Université de Rennes (UR)

Publications

L’impact des polluants environnementaux sur le tissu adipeux : liens avec l’obésité 20 ans d’obésogènes : les données s’accumulent

Matthieu Masaoudi , Etienne B Blanc , Xavier Coumoul , Min Ji Kim

Médecine des Maladies Métaboliques, 2026, ⟨10.1016/j.mmm.2026.09.009⟩

Article dans une revue hal-05779186v1

Chemical fate in vitro: A physiological biokinetic (PBK) model for cell-based assays

Daniela Brenner , Kévin Bernal , Eliska Sychrova , Jiří Kohoutek , Sophie Langouët et al.

ALTEX - Alternatives to Animal Experimentation, 2026, ⟨10.14573/altex.2509261⟩

Article dans une revue hal-05456518v1

Liver steatosis induced by per- and polyfluoroalkyl substances exerts a limited influence on heterocyclic aromatic amine–mediated DNA damage at population-relevant exposure levels

Minna A. Choi , Frederic Ezan , Matthieu Masaoudi , Etienne B Blanc , Sophie Langouët

Environmental Pollution, 2026, 397, pp.127975. ⟨10.1016/j.envpol.2026.127975⟩

Article dans une revue hal-05579811v1

Mapping DEHP-induced metabolic dysregulation through multi-omics and systems biology: an adverse outcome pathway network approach

Elisavet Renieri , Achilleas Karakoltzidis , Nafsika Papaioannou , Dayna R. Schultz , Thanasis Papageorgiou et al.

Frontiers in Toxicology, 2026, 8, pp.1930835. ⟨10.3389/ftox.2026.1930835⟩

Article dans une revue hal-05779236v1

Assessment of endocrine disruptor impact on carbohydrate metabolism in the HepaRG human hepatic cell line

Kévin Bernal , Arnaud Tête , Béatrice Le-Grand , Patrick Balaguer , Min Ji Kim et al.

Archives of Toxicology, 2026, 100, pp.1501-1513. ⟨10.1007/s00204-025-04291-x⟩

Article dans une revue hal-05493864v1

Mapping the Human Chemical Exposome for Public Health

Arthur David , Sarah Lennon , Fabien Mercier , Jihene Bouhlel , Jade Chaker et al.

Nature Medicine, 2026, ⟨10.1038/s41591-026-04289-7⟩

Article dans une revue hal-05570286v1

Repeated exposure to polyethylene microplastic mixtures containing PFAS and bisphenols activates THP-1 macrophages with inflammatory features

Lucas Gaillard , Léo Sportes-Milot , Kloé Debizet , Arnaud Tête , Bruno Saubamea et al.

Environmental Pollution, 2026, 397, pp.127906. ⟨10.1016/j.envpol.2026.127906⟩

Article dans une revue hal-05752155v1

Park7 (DJ-1), a Parkinson-associated glyoxalase/deglycase: characterization of enzymatic activity in biological samples using fluorescence-based liquid chromatography

Nicolas Mathas , Emmanuelle Braud , Erwan Galardon , Lucie Larigot , Mélanie Etheve-Quelquejeu et al.

Biochimie, 2025, 235, pp.113-121. ⟨10.1016/j.biochi.2025.06.005⟩

Article dans une revue hal-05343900v1

Park7 (DJ-1), a Parkinson-associated glyoxalase/deglycase: characterization of enzymatic activity in biological samples using fluorescence-based liquid chromatography

Nicolas Mathas , Emmanuelle Braud , Erwan Galardon , Lucie Larigot , Mélanie Etheve-Quelquejeu et al.

Biochimie, 2025, 235, pp.113-121. ⟨10.1016/j.biochi.2025.06.005⟩

Article dans une revue hal-05468192v1

Digital Futures of Learning Pharmacology and Medicinal and Organic Chemistry

Fun Man Fung , Etienne Blanc , Xavier Coumoul

ACS Pharmacology & Translational Science, 2024, 7 (4), pp.1191-1194. ⟨10.1021/acsptsci.4c00043⟩

Article dans une revue hal-04668583v1

Assessment of endocrine disruptor impacts on lipid metabolism in a fatty acid-supplemented HepaRG human hepatic cell line

Kévin Bernal , Charbel Touma , Béatrice Le Grand , Sophie Rose Reyhan Basaran , Selenay Degerli et al.

Chemosphere, 2024, Chemosphere, 349, pp.140883. ⟨10.1016/j.chemosphere.2023.140883⟩

Article dans une revue hal-04356246v1

Per- and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts

Lucas Gaillard , Robert Barouki , Etienne Blanc , Xavier Coumoul , Karine Andréau

Trends in Endocrinology and Metabolism = Trends in Endocrinology & Metabolism , 2024, ⟨10.1016/j.tem.2024.07.021⟩

Article dans une revue hal-04748588v1

Costs of molecular adaptation to the chemical exposome: a focus on xenobiotic metabolism pathways

Céline Tomkiewicz , Xavier Coumoul , Pierre Nioche , Robert Barouki , Etienne B Blanc

Philosophical Transactions of the Royal Society B: Biological Sciences, 2024, 379 (1898), pp.20220510. ⟨10.1098/rstb.2022.0510⟩

Article dans une revue (article de synthèse) hal-04669203v1

ReadEDTest: A tool to assess the readiness of in vitro test methods under development for identifying endocrine disruptors

Thibault Crouzet , Elise Grignard , François Brion , Etienne B Blanc , Normand Podechard et al.

Environment International, 2023, 174, pp.107910. ⟨10.1016/j.envint.2023.107910⟩

Article dans une revue hal-04094681v1

Innovative tools and methods for toxicity testing within PARC work package 5 on hazard assessment

Thalia de Castelbajac , Kiara Aiello , Celia Garcia Arenas , Terje Svingen , Louise Ramhøj et al.

Frontiers in Toxicology, 2023, 5, pp.1216369. ⟨10.3389/ftox.2023.1216369⟩

Article dans une revue anses-04193760v1

The effects of pollutant mixture released from grafted adipose tissues on fatty acid and lipid metabolism in the skeletal muscles, kidney, heart, and lungs of male mice

Gideon Lam , Phillipe Noirez , Haidar Djemai , Layale Youssef , Etienne Blanc et al.

Environmental Pollution, 2023, 336, pp.122387. ⟨10.1016/j.envpol.2023.122387⟩

Article dans une revue hal-04182516v1

The exposome and liver disease - how environmental factors affect liver health

Robert Barouki , Michel Samson , Etienne B Blanc , Massimo Colombo , Jessica Zucman-Rossi et al.

Journal of Hepatology, 2023, 79 (2), pp.492-505. ⟨10.1016/j.jhep.2023.02.034⟩

Article dans une revue hal-04041202v1

Associations between perfluoroalkyl substances and the severity of non-alcoholic fatty liver disease

Norma David , Jean-Philippe Antignac , Marine Roux , Philippe Marchand , Sophie Michalak et al.

Environment International, 2023, 180, pp.108235. ⟨10.1016/j.envint.2023.108235⟩

Article dans une revue hal-04382856v1

SDHi fungicides: An example of mitotoxic pesticides targeting the succinate dehydrogenase complex

Carolina Duarte Hospital , Arnaud Tête , Kloé Debizet , Jules Imler , Céline Tomkiewicz-Raulet et al.

Environment International, 2023, 180, pp.108219. ⟨10.1016/j.envint.2023.108219⟩

Article dans une revue hal-04748812v1

SDHi fungicides: An example of mitotoxic pesticides targeting the succinate dehydrogenase complex

Carolina Duarte Hospital , Arnaud Tête , Kloé Debizet , Jules Imler , Céline Tomkiewicz-Raulet et al.

Environment International, 2023, 180, pp.108219. ⟨10.1016/j.envint.2023.108219⟩

Article dans une revue hal-04627140v1

Alternatives in vitro et in silico aux modèles animaux en toxicologie

Arnaud Tete , Elias Zgheib , Sana Al Awabdh , Louise Benoit , Kévin Bernal et al.

Nanotechnologies et biotechnologies pour la santé, 2022, ⟨10.51257/a-v1-re295⟩

Article dans une revue hal-04765585v1

Obesity II: Establishing causal links between chemical exposures and obesity

Jerrold J Heindel , Sarah Howard , Keren Agay-Shay , Juan P Arrebola , Karine Audouze et al.

Biochemical Pharmacology, 2022, 199, pp.115015. ⟨10.1016/j.bcp.2022.115015⟩

Article dans une revue hal-03705630v1

Corrigendum to “Obesity II: Establishing causal links between chemical exposures and obesity” [Biochem. Pharmacol. 199 (2022) 115015]

Jerrold J Heindel , Sarah Howard , Keren Agay-Shay , Juan P Arrebola , Karine Audouze et al.

Biochemical Pharmacology, 2022, 202, ⟨10.1016/j.bcp.2022.115144⟩

Article dans une revue hal-05622044v1

Obesity I: Overview and molecular and biochemical mechanisms

Robert Lustig , David Collier , Christopher Kassotis , Troy Roepke , Min Ji Kim et al.

Biochemical Pharmacology, 2022, 199, pp.115012. ⟨10.1016/j.bcp.2022.115012⟩

Article dans une revue hal-03843296v1

Toxicological effects of 2,3,7,8 tetrachlorodibenzo-p-dioxin on the skeletal muscle of mice during the perinatal period: a metabolomics study

Gideon Lam , Ludmila Juricek , Hiranya Dayal , Anna Karen Carrasco Laserna , Medhi Hichor et al.

Environmental Sciences Europe , 2022, 34 (1), pp.57. ⟨10.1186/s12302-022-00633-z⟩

Article dans une revue hal-04182519v1

Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors

Kévin Bernal , Charbel Touma , Chedi Erradhouani , Talía Boronat-Belda , Lucas Gaillard et al.

FEBS Letters, 2022, Lisbon Virtual Issue Reviews, 596 (24), pp.3107-3123. ⟨10.1002/1873-3468.14465⟩

Article dans une revue hal-04765488v1

Alternatives in vitro et in silico aux modèles animaux en toxicologie

Arnaud Tete , Elias Zgheib , Sana Al Awabdh , Louise Benoit , Kévin Bernal et al.

Nanotechnologies et biotechnologies pour la santé, 2022, ⟨10.51257/a-v1-re295⟩

Article dans une revue hal-05752223v1

Alternatives in vitro et in silico aux modèles animaux en toxicologie

Arnaud Tete , Elias Zgheib , Sana Al Awabdh , Louise Benoit , Kévin Bernal et al.

Nanotechnologies et biotechnologies pour la santé, 2022, ⟨10.51257/a-v1-re295⟩

Article dans une revue hal-04627223v1

Mitochondrial Dysfunction as a Hallmark of Environmental Injury

Carolina Duarte-Hospital , Arnaud Tête , François Brial , Louise Benoit , Meriem Koual et al.

Cells, 2021, 11 (1), pp.110. ⟨10.3390/cells11010110⟩

Article dans une revue hal-04627137v1

Que sait-on de l’action des perturbateurs endocriniens sur le système immunitaire ?

Jérôme Estaquier , Étienne Blanc , Xavier Coumoul

La Revue du Praticien Médecine Générale, 2021, 71 (7), pp.729-734

Article dans une revue hal-03744699v1

Mitochondrial Dysfunction as a Hallmark of Environmental Injury

Carolina Duarte-Hospital , Arnaud Tête , François Brial , Louise Benoit , Meriem Koual et al.

Cells, 2021, 11 (1), pp.110. ⟨10.3390/cells11010110⟩

Article dans une revue hal-03744739v1

Mitochondrial Dysfunction as a Hallmark of Environmental Injury

Carolina Duarte-Hospital , Arnaud Tête , François Brial , Louise Benoit , Meriem Koual et al.

Cells, 2021, 11 (1), pp.110. ⟨10.3390/cells11010110⟩

Article dans une revue hal-05756002v1

Interacting with Three-Dimensional Molecular Structures Using an Augmented Reality Mobile App

Jonah Kailer Aw , Kevin Christopher Boellaard , Teck Kiang Tan , John Yap , Yi Ping Loh et al.

Journal of Chemical Education, 2020, 97 (10), pp.3877-3881. ⟨10.1021/acs.jchemed.0c00387⟩

Article dans une revue hal-03154348v1

Applying a Virtual Reality Platform in Environmental Chemistry Education To Conduct a Field Trip to an Overseas Site

Fun Man Fung , Wen Yi Choo , Alvita Ardisara , Christoph Dominik Zimmermann , Simon Watts et al.

Journal of Chemical Education, 2019, 96 (2), pp.382-386. ⟨10.1021/acs.jchemed.8b00728⟩

Article dans une revue hal-04026750v1

A dual mixture of persistent organic pollutants modifies carbohydrate metabolism in the human hepatic cell line HepaRG

Alix Leblanc , Eléonore Attignon , Emilie Distel , Spyros Karakitsios , Dimosthenis Sarigiannis et al.

Environmental Research, 2019, 178, pp.108628. ⟨10.1016/j.envres.2019.108628⟩

Article dans une revue hal-05756001v1

Aryl hydrocarbon receptor and liver fibrosis

Caroline Duval , Etienne Blanc , Xavier Coumoul

Current Opinion in Toxicology, 2018, 8, pp.8-13. ⟨10.1016/j.cotox.2017.11.010⟩

Article dans une revue hal-02196325v1

Impact of Dyrk1A level on alcohol metabolism

Fabrice Daubigney , Cindy Bokobza , Marie Mortreux , Jean-Louis Paul , Jean-Maurice Delabar et al.

Biochimica et Biophysica Acta - Molecular Basis of Disease, 2016, 1862 (9), pp.1495-1503. ⟨10.1016/j.bbadis.2016.05.011⟩

Article dans une revue istex hal-04749737v1

Combination of lipid metabolism alterations and their sensitivity to inflammatory cytokines in human lipin-1-deficient myoblasts

Caroline Michot , Asmaa Mamoune , Joseph Vamecq , Mai Thao Viou , Lu-Sheng Hsieh et al.

Biochimica et Biophysica Acta - Molecular Basis of Disease, 2013, 1832 (12), pp.2103-2114. ⟨10.1016/j.bbadis.2013.07.021⟩

Article dans une revue hal-05612593v1

Hypoxia down-regulates CCAAT/enhancer binding protein-alpha expression in breast cancer cells.

Ramzi Seifeddine , Anne Dreiem , Etienne Blanc , Marie-Claude Fulchignoni-Lataud , Marie-Aude Le Frère Belda et al.

Cancer Research, 2008, 68 (7), pp.2158-65. ⟨10.1158/0008-5472.CAN-07-1190⟩

Article dans une revue hal-00330651v1

Stabilization of IGFBP-1 mRNA by ethanol in hepatoma cells involves the JNK pathway

Laurent Magne , Etienne Blanc , Alexandre Marchand , Pierre Fafournoux , Robert Barouki et al.

Journal of Hepatology, 2007, 47 (5), pp.691-698. ⟨10.1016/j.jhep.2007.05.018⟩

Article dans une revue istex hal-02664643v1

Mapping the Human Chemical Exposome for Public Health

Arthur David , Sarah Lennon , Fabien Mercier , Jihene Bouhlel , Jade Chaker et al.

2026

Pré-publication, Document de travail hal-05557890v1

Disruption of biological communication

Robert Barouki , Etienne Blanc , Xavier Coumoul

86 (3), pp.101766, 2025, ⟨10.1016/j.ando.2025.101766⟩

Ouvrages hal-05432127v1

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