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Etienne THEVENOT

Responsable de l'équipe sciences des données métabolomiques pour la santé (Odiscé)
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29
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  • 1158713
  • 1076048
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# Professional experience **Current professional status** * Since 2020: Leader of the Metabolomics Data Sciences for Health team (CEA, Fundamental Research Division); CDI, full time devoted to research activities. * Since 2022: Co-leader of the multimodal integration workpackage from PROPSY (PEPR Exploratoire in precision psychiatry) * Since 2021: In charge of the multimodal data integration roadmap at CEA **Previous positions** * 2005-2019: Data scientist (CEA Tech); CDI, full time devoted to research activities. * 2017-2021: Co-leader of the Integrative Bioinformatics task from IFB (French Institute of Bioinformatics) * 2013-2017: Leader of the Bioinformatics workpackage from MetaboHUB (French infrastructure in metabolomics and fluxomics) # Academic background * Habilitation à Diriger les Recherches en Informatique (2023). University Paris-Saclay. Ecole Doctorale “Sciences and Technologies of Information and Communication” (STIC; ED580). * Post-doctorate (2004-2005): Gene therapy and molecular imaging of neurodegenerative diseases (Neurodegenerative Diseases Laboratory, Molecular Imaging Research Center, MIRCen, CEA) * PhD in Molecular and Cellular Biology (2003). Pierre and Marie Curie University, Paris. Laboratoire de Génétique de la Neurotransmission et des Processus Neurodégénératifs (CNRS UMR 7091, Hôpital de la Pitié-Salpêtrière, Paris) * Diplôme d’Université (DU) in Higher Biomedical Education (2001). Paris-Sud University, Orsay. * Master of Molecular and Cellular Biology (1997). Pierre and Marie Curie University, Paris. * Master of Science and Executive Engineering (1996). MINES ParisTech graduate school, Paris.

Research domains


Skills

traitement du signal apprentissage automatique apprentissage profond sélection de variables intégration des données métabolomique

Publications

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Scaling-up metabolomics: Current state and perspectives

Ghina Hajjar , Millena Cristina Barros Santos , Justine Bertrand-Michel , Cécile Canlet , Florence A Castelli
Trends in Analytical Chemistry, 2023, 167 (20), pp.117225. ⟨10.1016/j.trac.2023.117225⟩
Journal articles hal-04188505v1
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ptairMS: real-time processing and analysis of PTR-TOF-MS data for biomarker discovery in exhaled breath

Camille Roquencourt , Stanislas Grassin-Delyle , Etienne A Thévenot
Bioinformatics, 2022, 38 (7), pp.1930-1937. ⟨10.1093/bioinformatics/btac031⟩
Journal articles cea-03598858v1
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Bariatric Surgery Improves the Atherogenic Profile of Circulating Methylarginines in Obese Patients: Results from a Pilot Study

Julie Poirier , Chloé Cloteau , Audrey Aguesse , Xavier Billot , Etienne Thévenot
Metabolites, 2021, 11 (11), pp.759. ⟨10.3390/metabo11110759⟩
Journal articles hal-03653351v1
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Metabolomics of exhaled breath in critically ill COVID-19 patients: A pilot study

Stanislas Grassin-Delyle , Camille Roquencourt , Pierre Moine , Gabriel Saffroy , Stanislas Carn
EBioMedicine, 2021, 63, pp.103154. ⟨10.1016/j.ebiom.2020.103154⟩
Journal articles cea-03086093v1
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Differential effects of post-weaning diet and maternal obesity on mouse liver and brain metabolomes

Sofiane Safi-Stibler , Mélanie Jouin , Etienne A Thévenot , Luc Jouneau , Alexandre Seyer
Nutrients, 2020, 12 (6), pp.1572. ⟨10.3390/nu12061572⟩
Journal articles hal-02867469v1
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Metabolic reprograming of LPS-stimulated human lung macrophages involves tryptophan metabolism and the aspartate-arginosuccinate shunt

Fanta Fall , Elodie Lamy , Marion Brollo , Emmanuel Naline , Natacha Lenuzza
PLoS ONE, 2020, 15 (4), pp.e0230813. ⟨10.1371/journal.pone.0230813⟩
Journal articles inserm-02543848v1
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Interoperable and scalable data analysis with microservices: applications in metabolomics

Payam Emami Khoonsari , Pablo Moreno , Sven Bergmann , Joachim Burman , Marco Capuccini
Bioinformatics, 2019, 35 (19), pp.3752-3760. ⟨10.1093/bioinformatics/btz160⟩
Journal articles cea-04562419v1
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Create, run, share, publish, and reference your LC-MS, FIA-MS, GC-MS, and NMR data analysis workflows with the Workflow4Metabolomics 3.0 Galaxy online infrastructure for metabolomics

Yann Guitton , Marie Tremblay-Franco , Gildas A Le Corguillé , Jean-Francois Martin , Mélanie Pétéra
International Journal of Biochemistry and Cell Biology, 2017, 93, pp.89-101. ⟨10.1016/j.biocel.2017.07.002⟩
Journal articles hal-01574351v1
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The future of metabolomics in ELIXIR

M. van Rijswijk , C. Beirnaert , C. Caron , M. Cascante , V. Dominguez
F1000Research, 2017, 6 (Version 2), ⟨10.12688/f1000research.12342.2⟩
Journal articles hal-01630635v1

biosigner: A New Method for the Discovery of Significant Molecular Signatures from Omics Data

Philippe Rinaudo , Samia Boudah , Christophe Junot , Etienne Thévenot
Frontiers in Molecular Biosciences, 2016, 3, ⟨10.3389/fmolb.2016.00026⟩
Journal articles hal-01869335v1
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Safety and pharmacokinetics of the CIME combination of drugs and their metabolites after a single oral dosing in healthy volunteers

Natacha Lenuzza , Xavier Duval , Grégory Nicolas , Etienne Thévenot , Sylvie Job
European journal of drug metabolism and pharmacokinetics, 2016, 41 (2), pp.125-138. ⟨10.1007/s13318-014-0239-0⟩
Journal articles hal-01868750v1
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Workflow4Metabolomics: A collaborative research infrastructure for computational metabolomics

Franck Giacomoni , Gildas Le Corguillé , Misharl Monsoor , Marion Landi , Pierre Pericard
Bioinformatics, 2015, 31 (9), pp.1493-1495. ⟨10.1093/bioinformatics/btu813⟩
Journal articles hal-01123263v1

Impact of collection conditions on the metabolite content of human urine samples as analyzed by liquid chromatography coupled to mass spectrometry and nuclear magnetic resonance spectroscopy

Aurélie Roux , Etienne Thévenot , François Seguin , Marie-Françoise Olivier , Christophe Junot
Metabolomics, 2015, 11 (5), pp.1095 - 1105. ⟨10.1007/s11306-014-0764-5⟩
Journal articles hal-01864965v1

Analysis of the Human Adult Urinary Metabolome Variations with Age, Body Mass Index, and Gender by Implementing a Comprehensive Workflow for Univariate and OPLS Statistical Analyses

Etienne Thévenot , Aurélie Roux , Ying Xu , Eric Ezan , Christophe Junot
Journal of Proteome Research, 2015, 14 (8), pp.3322 - 3335. ⟨10.1021/acs.jproteome.5b00354⟩
Journal articles cea-01865435v1
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Technological developments and opportunities with Workflow4Metabolomics

Mélanie Pétéra , Yann Guitton , Charlotte Joly , Florence Souard , Etienne A Thévenot
ISMB/ECCB 2023: The 31st Annual Intelligent Systems For Molecular Biology and the 22nd Annual European Conference on Computational Biology, Jul 2023, Lyon, France
Conference poster hal-04185176v1

Automatic search for chemical exposure markers in LC-HRMS metabolomic data

Dylan Saunier , Eric Venot , Sylvain Dechaumet , N Behkti , Blanche Guillon
15èmes Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique, May 2023, Perpignan, France
Conference poster hal-04644047v1

Integrated Multi-omics of early breast milk constituents

Camilo Broc , Karine Adel-Patient , François Fenaille , Mikaïl Berdi , Eric Venot
Intelligent Systems for Molecular Biology/European Conference on computaional biology, Jul 2021, Virtuel, France
Conference poster hal-03739277v1
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Development and characterization of electronic noses for the rapid detection of COVID-19 in exhaled breath

Christelle Ghazaly , Krystyna Biletska , Etienne A Thévenot , Philippe Devillier , Emmanuel Naline
10th Franco-Spanish Workshop CMC2-IBERNAM, Nov 2021, Arcachon, France.
Conference poster cea-03713273v1
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Optimized selection process to identify a metabolic syndrome metabolomic/lipidomic signature in older adults of the NuAge cohort

Natacha Lenuzza , Etienne Thévenot , Mélanie Pétéra , Stéphanie Monnerie , José A Morais
13. Congress of the European Union Geriatric Medicine Society (EUGMS), Sep 2017, Nice, France. European Geriatric Medicine, 8, 276 p., 2017, Abstracts of the 13th International Congress of the European Union Geriatric Medicine Society –Developing Preventive Actions in Geriatrics
Conference poster hal-02736369v1
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PeakForest: a spectral database and its toolbox, dedicated to the Metabolomics’ community

Nils Paulhe , Christophe Duperier , Marie Lefebvre , Pierrick Roger-Mele , Christophe Junot
12. annual conference of the Metabolomics Society, Jun 2016, Dublin, United Kingdom. 2016
Conference poster hal-02744357v1

PeakForest: a spectral reference database made from metabolomic experts for metabolomic analyses

Nils Paulhe , Pierrick Roger , Marie-Françoise Olivier , Marie Lefebvre , Christophe Duperier
9. Journées scientifiques du RFMF, Jun 2015, Lille, France. 2015
Conference poster hal-02742964v1
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Workflow4Metabolomics: A collaborative research infrastructure for computational metabolomics

Mélanie Pétéra , Gildas Le Corguille , Marion Landi , Misharl Monsoor , Marie Tremblay-Franco
JOBIM 2015 (16e édition des Journées Ouvertes en Biologie, Informatique et Mathématiques ), Jul 2015, Clermont-Ferrand, France. , 2015, JOBIM (16e édition des Journées Ouvertes en Biologie, Informatique et Mathématiques ). ⟨10.1093/bioinformatics/btu813⟩
Conference poster hal-01214152v1
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New tools and workflows on W4M, the Galaxy metabolomic infrastructure

Marion Landi , Claire Lopez , Marie Tremblay-Franco , Cécile Canlet , Yann Guitton
9e Journées scientifiques du RFMF, Jun 2015, Lille, France. , 2015
Conference poster hal-02743697v1
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Factory and Libraries for Automatic Metabolomic Exploration : F.L.A.M.E

Marion Landi , Mélanie Pétéra , Mishari Monsoor , Gildas Le Corguillé , Christophe Duperier
8. Journées Scientifiques du Réseau Français de Métabolomique et Fluxomique RFMF, May 2014, Lyon, France. 2014
Conference poster hal-02743239v1
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Spectral Database: from data model to web interface

Nils Paulhe , Christophe Duperier , Daniel Jacob , Etienne Thévenot , Jean-Francois Martin
8. Journées Scientifiques du Réseau Français de Métabolomique et Fluxomique RFMF, May 2014, Lyon, France. 2014
Conference poster hal-02742064v1
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Mass Spectrometry Imaging visualization tools developed during the Computis European project

Marie-France Robbe , Etienne A Thévenot , Markus Stoeckli , Alfons Hester , Andreas Roempp
Congrès français de spectrométrie de masse et d'analyse protéomique (SMAP 2011), Sep 2011, Avignon, France. Book of abstracts of SMAP 2011
Conference poster cea-03086461v1