Eva Jakab Toth

289
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Publications

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Supramolecular rotaxanes and polyrotaxanes as potential MRI contrast agents: a comprehensive 17O NMR and relaxometric study

Jean Wilfried Fredy , Jérémy Scelle , Bernold Hasenknopf , Éva Tóth , Guillaume Vives et al.

Inorganica Chimica Acta, 2026, 589, pp.122947. ⟨10.1016/j.ica.2025.122947⟩

Article dans une revue hal-05362359v1
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Stability and relaxometric characterization of a manganase(II) based macrocyclic complex containing malonate pendant

Abraham Estifanos Debretsion , Szilvia Bunda , Norbert Lihi , Zoltán Garda , Sabine van Doorslaer et al.

Dalton Transactions, 2025, 54 (27), pp.10751-10760. ⟨10.1039/D5DT01056J⟩

Article dans une revue hal-05362352v1
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Mn <sup>2+</sup> Complex of a Fluorinated CDTA‐Derivative: Stability, Inertness, and Paramagnetic <sup>1</sup> H, <sup>17</sup> O, and <sup>19</sup> F Relaxation Properties

Zoltán Garda , Agnès Pallier , Tibor Nagy , Frédéric Szeremeta , Éva Tóth

Chemistry - A European Journal, 2025, Online ahead of print. ⟨10.1002/chem.202502751⟩

Article dans une revue hal-05362363v1
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Relaxation-Based In Vivo Discrimination of Oxidized and Reduced States of a Redox-Switchable <sup>19</sup>F MRI Probe

Zoltán Garda , Frédéric Szeremeta , Csilla Noémi Tóth , Szilvia Bunda , Carlo Pifferi et al.

Journal of the American Chemical Society, 2025, 147 (21), pp.18017-18024. ⟨10.1021/jacs.5c03244⟩

Article dans une revue hal-05190999v1
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Molecular and supramolecular routes to enhance Gadolinium-based contrast agents relaxivity: How far are we from the theoretical optimal value?

Lorenzo Palagi , Dario Livio Longo , Éva Tóth , Carlo C Quattrocchi , Aart J van der Molen et al.

European Journal of Medicinal Chemistry, 2025, 292, pp.117668. ⟨10.1016/j.ejmech.2025.117668⟩

Article dans une revue hal-05362335v1
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Exploring a Rigid Macrocyclic Ligand Bearing Malonate Pendants for Gd(III) Complexation: the Coordination Chemistry of [Gd(OPDMA)]<sup>−</sup>

Abraham Estifanos Debretsion , Szilvia Bunda , Norbert Lihi , Gábor Papp , Agnés Pallier et al.

Inorganic Chemistry, 2025, 64 (21), pp.10594-10602. ⟨10.1021/acs.inorgchem.5c01224⟩

Article dans une revue hal-05362345v1
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Expanding the Family of Monosubstituted 15-Membered Pyridine-Based Macrocyclic Ligands for Mn(II) Complexation in the Context of MRI

Marie Pražáková , Daouda Ndiaye , Éva Tóth , Bohuslav Drahoš

Inorganic Chemistry, 2025, 64 (16), pp.8205-8221. ⟨10.1021/acs.inorgchem.5c00452⟩

Article dans une revue hal-05362309v1
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Towards more efficient, more specific, and safer MRI contrast agents: a Portuguese–French collaborative journey

Sara Martinho Almeida Pinto , Sara Lacerda , Jean-François Morfin , Rafael Tiago Aroso , Daniela Sofia de Sousa Teixeira et al.

Comptes Rendus. Chimie, 2025, 28 (G1), pp.95-110. ⟨10.5802/crchim.363⟩

Article dans une revue hal-05184946v1
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Mn 2+ Bispidine Complexes as Potential Magnetic Resonance Imaging Agents : Noncoordinating Peripheral Functional Groups Affect Structural, Kinetic, and Relaxation Properties

Maryame Sy , Daouda Ndiaye , Hervé Meudal , Loïc J Charbonnière , Aline M Nonat et al.

ChemistryEurope, 2025, ⟨10.1002/ceur.202500263⟩

Article dans une revue hal-05348993v1
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Exploring the Coordination Chemistry and Potential Applications of PC3PA-Based Lanthanide Complexes: Synthesis, Solution Structure, Luminescence, and Relaxation Properties

Loëza Collobert , Lucile Bridou , Zoltán Garda , Olivier Maury , Éva Tóth et al.

Inorganic Chemistry, 2025, 64 (18), pp.9330-9341. ⟨10.1021/acs.inorgchem.5c01318⟩

Article dans une revue hal-05096028v1
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Octadentate Bispidine Chelators for Tb(III) Complexation: Pyridine Carboxylate versus Pyridine Phosphonate Donors

Lucas Petitpoisson , Anli Mahamoud , Valérie Mazan , Maryame Sy , Olivier Jeannin et al.

Inorganic Chemistry, 2024, 63 (48), pp.22829-22844. ⟨10.1021/acs.inorgchem.4c03691⟩

Article dans une revue hal-04805202v1
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Small, Fluorinated Mn 2+ Chelate as an Efficient 1 H and 19 F MRI Probe

Zoltán Garda , Frédéric Szeremeta , Océane Quin , Enikő Molnár , Balázs G Váradi et al.

Angewandte Chemie International Edition, 2024, 63 (43), pp.e202410998. ⟨10.1002/anie.202410998⟩

Article dans une revue hal-04780796v1
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Lanthanide‐Based Probes for Imaging Detection of Enzyme Activities by NIR Luminescence, T1‐ and ParaCEST MRI

Rémy Jouclas , Sophie Laine , Svetlana V. Eliseeva , Jérémie Mandel , Frédéric Szeremeta et al.

Angewandte Chemie International Edition, 2024, 63 (16), pp.e202317728. ⟨10.1002/anie.202317728⟩

Article dans une revue hal-04634298v1
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Water-Soluble Mn(III)-Porphyrins with High Relaxivity and Photosensitization

Tamas Nemeth , Agnès Pallier , Çetin Çelik , Zoltán Garda , Naoko Yoshizawa-Sugata et al.

Chemical & Biomedical Imaging, 2024, ⟨10.1021/cbmi.4c00046⟩

Article dans une revue hal-04780802v1
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Structural, stability and relaxation features of lanthanide‐complexes designed for multimodal imaging detection of enzyme activities

Sophie Laine , Rémy Jouclas , Celia ́ Bonnet , Pascal Retailleau , Vincent Steinmetz et al.

European Journal of Inorganic Chemistry, 2024, 27 (14), pp.e202317728. ⟨10.1002/ejic.202300784⟩

Article dans une revue hal-04786265v1
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Peptide-conjugated MRI probe targeted to Netrin-1, a novel metastatic breast cancer biomarker

Clémentine Moreau , Tea Lukačević , Agnès Pallier , Julien Sobilo , Samia Aci-Sèche et al.

Bioconjugate Chemistry, 2024, 35 (2), pp.265-275. ⟨10.1021/acs.bioconjchem.3c00558⟩

Article dans une revue hal-04630981v1
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Stable and inert manganese complexes for magnetic resonance imaging

Daouda Ndiaye , Éva Tóth

Comptes Rendus. Chimie, 2024, 27 (S2), pp.161 - 177. ⟨10.5802/crchim.284⟩

Article dans une revue hal-04780758v1
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Water-Soluble Gd(III)–Porphyrin Complexes Capable of Both Photosensitization and Relaxation Enhancement

Tamas Nemeth , Naoko Yoshizawa-Sugata , Agnes Pallier , Youichi Tajima , Yue Ma et al.

Chemical & Biomedical Imaging, 2023, 1 (2), pp.157-167. ⟨10.1021/cbmi.3c00007⟩

Article dans une revue hal-04288624v1
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A seven-coordinate Mn( ii ) complex with a pyridine-based 15-membered macrocyclic ligand containing one acetate pendant arm: structure, stability and relaxation properties

Marie Pražáková , Daouda Ndiaye , Éva Tóth , Bohuslav Drahoš

Dalton Transactions, 2023, 52 (23), pp.7936-7947. ⟨10.1039/d3dt00701d⟩

Article dans une revue hal-04288621v1
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Gd 3+ Complexes for MRI Detection of Zn 2+ in the Presence of Human Serum Albumin: Structure–Activity Relationships

Kyangwi Malikidogo , Manon Isaac , Adrien Uguen , Jean-François Morfin , Gyula Tircsó et al.

Inorganic Chemistry, 2023, 62 (42), pp.17207-17218. ⟨10.1021/acs.inorgchem.3c02280⟩

Article dans une revue hal-04258789v1
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Zinc-sensitive MRI contrast agents: importance of local probe accumulation in zinc-rich tissues

Kyangwi Malikidogo , Manon Isaac , Adrien Uguen , Sandra Même , Agnès Pallier et al.

Chemical Communications, 2023, 59, pp.12883-12886. ⟨10.1039/D3CC03137C⟩

Article dans une revue hal-04254714v1
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Fluorinated Mn(III)/(II)‐Porphyrin with Redox‐Responsive 1 H and 19 F Relaxation Properties

Sara Pinto , Ana Ferreira , Daniela Teixeira , Sandra Nunes , Ana Batista de Carvalho et al.

Chemistry - A European Journal, 2023, 29 (53), ⟨10.1002/chem.202301442⟩

Article dans une revue hal-04288630v1
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Structural Variations in Carboxylated Bispidine Ligands: Influence of Positional Isomerism and Rigidity on the Conformation, Stability, Inertness and Relaxivity of their Mn 2+ Complexes

Daouda Ndiaye , Maryame Sy , Waygen Thor , Loïc Charbonnière , Aline Nonat et al.

Chemistry - A European Journal, 2023, 29 (62), pp.e202301880. ⟨10.1002/chem.202301880⟩

Article dans une revue hal-04249989v1
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On the Versatility of Nanozeolite Linde Type L for Biomedical Applications: Zirconium-89 Radiolabeling and In Vivo Positron Emission Tomography Study

Sara Lacerda , Wuyuan Zhang , Rafael T. M. de Rosales , Isidro da Silva , Julien Sobilo et al.

ACS Applied Materials & Interfaces, 2022, 14 (29), pp.32788-32798. ⟨10.1021/acsami.2c03841⟩

Article dans une revue hal-03810569v1
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<sup>55/52</sup>Mn<sup>2+</sup> Complexes with a Bispidine-Phosphonate Ligand: High Kinetic Inertness for Imaging Applications

Maryame Sy , Daouda Ndiaye , Isidro da Silva , Sara Lacerda , Loïc J. Charbonnière et al.

Inorganic Chemistry, 2022, 61 (34), pp.13421-13432. ⟨10.1021/acs.inorgchem.2c01681⟩

Article dans une revue hal-03769013v1
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Gd III and Ga III complexes with a new tris-3,4-HOPO ligand as new imaging probes: complex stability, magnetic properties and biodistribution

Silvia Chaves , Karolina Gwizdała , Karam Chand , Lurdes Gano , Agnes A. Pallier et al.

Dalton Transactions, 2022, 51 (16), pp.6436-6447. ⟨10.1039/D2DT00066K⟩

Article dans une revue hal-03842391v1
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Rigidified Derivative of the Non-macrocyclic Ligand H 4 OCTAPA for Stable Lanthanide(III) Complexation

Fátima Lucio-Martínez , Zoltán Garda , Balázs Váradi , Ferenc Krisztián Kálmán , David Esteban-Gómez et al.

Inorganic Chemistry, 2022, 61 (12), pp.5157-5171. ⟨10.1021/acs.inorgchem.2c00501⟩

Article dans une revue hal-03842348v1
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Metal complexes for the visualisation of amyloid peptides

Jean-François Morfin , Sara Lacerda , Carlos F G C Geraldes , Éva Tóth

Sensors & Diagnostics, 2022, 1 (4), pp.627 - 647. ⟨10.1039/d2sd00026a⟩

Article dans une revue hal-03810610v1
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Exceptional Manganese(II) Stability and Manganese(II)/Zinc(II) Selectivity with Rigid Polydentate Ligands**

Patrick Cieslik , Peter Comba , Benedikt Dittmar , Daouda Ndiaye , Éva Tóth et al.

Angewandte Chemie International Edition, 2022, 61 (10), ⟨10.1002/anie.202115580⟩

Article dans une revue hal-03842387v1
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Mn 2+ bispidine complex combining exceptional stability, inertness and MRI efficiency

Daouda Ndiaye , Patrick Cieslik , Hubert Wadepohl , Agnès Pallier , Sandra Même et al.

Journal of the American Chemical Society, 2022, 144 (48), pp.22212-22220. ⟨10.1021/jacs.2c10108⟩

Article dans une revue hal-04292599v1
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A New Oxygen Containing Pyclen-Type Ligand as a Manganese(II) Binder for MRI and 52Mn PET Applications: Equilibrium, Kinetic, Relaxometric, Structural and Radiochemical Studies

Tibor Csupász , Dániel Szücs , Ferenc Krisztián Kálmán , Oldamur Hollóczki , Anikó Fekete et al.

Molecules, 2022, 27 (2), pp.371. ⟨10.3390/molecules27020371⟩

Article dans une revue hal-03842397v1
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Concentration‐dependent interactions of amphiphilic PiB‐ derivative metal complexes with amyloid peptides Aβ and amylin

Saida Majdoub , Zoltán Garda , Alexandre Oliveira , Inga Relich , Agnes A. Pallier et al.

Chemistry - A European Journal, 2021, 27, pp.2009-2020. ⟨10.1002/chem.202004000⟩

Article dans une revue hal-03011656v1
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Stability, relaxometric and computational studies on Mn 2+ complexes with ligands containing a cyclobutane scaffold

Oriol Porcar-Tost , Agnès Pallier , David Esteban-Gómez , Ona Illa , Carlos Platas-Iglesias et al.

Dalton Transactions, 2021, 50 (3), pp.1076-1085. ⟨10.1039/D0DT03402A⟩

Article dans une revue hal-03442176v1
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Doxorubicin‐sensitized Luminescence of NIR‐emitting Ytterbium Liposomes: Towards Direct Monitoring of Drug Release

S. Lacerda , Anthony Delalande , Svetlana V. Eliseeva , Agnes A. Pallier , Celia ́ Bonnet et al.

Angewandte Chemie International Edition, 2021, 60 (44), pp.23574-23577. ⟨10.1002/anie.202109408⟩

Article dans une revue hal-03349106v1
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Gd3+ Complexes Conjugated to Cyclodextrins: Hydroxyl Functions Influence the Relaxation Properties

Anais Biscotti , François Estour , Berthe-Sandra Sembo-Backonly , Sebastien Balieu , Michaël Bosco et al.

Processes, 2021, 9 (2), pp.269. ⟨10.3390/pr9020269⟩

Article dans une revue hal-03127005v1
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Lanthanide DO3A-Complexes Bearing Peptide Substrates: The Effect of Peptidic Side Chains on Metal Coordination and Relaxivity

Sophie Laine , Jean-François Morfin , Mathieu Galibert , Vincent Aucagne , Celia ́ Bonnet et al.

Molecules, 2021, 26 (8), pp.2176. ⟨10.3390/molecules26082176⟩

Article dans une revue hal-03437152v1
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Metal-based environment-sensitive MRI contrast agents

Celia ́ Bonnet , Éva Tóth

Current Opinion in Chemical Biology, 2021, 61, pp.154-169. ⟨10.1016/j.cbpa.2021.01.013⟩

Article dans une revue hal-03437175v1
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Complexation of Mn(II) by Rigid Pyclen Diacetates: Equilibrium, Kinetic, Relaxometric, Density Functional Theory, and Superoxide Dismutase Activity Studies

Zoltán Garda , Enikő Molnár , Nadège Hamon , José Luis Barriada , David Esteban-Gómez et al.

Inorganic Chemistry, 2021, ⟨10.1021/acs.inorgchem.0c03276⟩

Article dans une revue hal-03094039v1
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Expanding the Ligand Classes Used for Mn(II) Complexation: Oxa-aza Macrocycles Make the Difference

Ferenc K Kálmán , Viktória Nagy , Rocío Uzal-Varela , Paulo Pérez-Lourido , David Esteban-Gómez et al.

Molecules, 2021, 26 (6), pp.1524. ⟨10.3390/molecules26061524⟩

Article dans une revue hal-03442182v1
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Synthesis and In Vitro Studies of a Gd(DOTA)–Porphyrin Conjugate for Combined MRI and Photodynamic Treatment

Sébastien Jenni , Celia ́ Bonnet , Frédéric Bolze , Agnes A. Pallier , Angélique Sour et al.

Inorganic Chemistry, 2020, 59 (19), pp.14389-14398. ⟨10.1021/acs.inorgchem.0c02189⟩

Article dans une revue hal-03011644v1
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Mn(II)-based MRI contrast agent candidate for vascular imaging

Ferenc K Kalman , Viktória Nagy , Balázs Váradi , Zoltán Garda , Enikő Molnár et al.

Journal of Medicinal Chemistry, 2020, 63 (11), pp.6057-6065. ⟨10.1021/acs.jmedchem.0c00197⟩

Article dans une revue hal-02996069v1
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Unprecedented kinetic inertness for a Mn2+‐bispidine chelate: a novel structural entry for Mn2+‐based imaging agents

Daouda Ndiaye , Maryame Sy , Agnès Pallier , Sandra Même , Isidro de Silva et al.

Angewandte Chemie International Edition, 2020, 59 (29), pp.11958-11963. ⟨10.1002/anie.202003685⟩

Article dans une revue hal-02555574v1
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Comparison of the equilibrium, kinetic and water exchange properties of some metal ion-DOTA and DOTA-bis(amide) complexes

Gyula Tircsó , Enikő Tircsóné Benyó , Zoltán Garda , Jaspal Singh , Robert Trokowski et al.

Journal of Inorganic Biochemistry, 2020, 206, pp.111042. ⟨10.1016/j.jinorgbio.2020.111042⟩

Article dans une revue hal-03011487v1
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Dual Imaging Gold Nanoplatforms for Targeted Radiotheranostics

Francisco Silva , António Paulo , Agnès Pallier , S. Même , Éva Tóth et al.

Materials, 2020, 13 (3), pp.513. ⟨10.3390/ma13030513⟩

Article dans une revue hal-02472491v1
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LDL-mimetic lipid nanoparticles prepared by surface KAT ligation for in vivo MRI of atherosclerosis

Alessandro Fracassi , Jianbo Cao , Naoko Yoshizawa-Sugata , Éva Tóth , Corey Archer et al.

Chemical Science, 2020, ⟨10.1039/d0sc04106h⟩

Article dans une revue hal-03011633v1
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Photophysical studies on lanthanide( iii ) chelates conjugated to Pittsburgh compound B as luminescent probes targeted to Aβ amyloid aggregates

Alexandre Oliveira , Telma Costa , Licinia Justino , Rui Fausto , Jean-François Morfin et al.

Photochemical & Photobiological Sciences , 2020, 19 (11), pp.1522-1537. ⟨10.1039/D0PP00214C⟩

Article dans une revue hal-03011501v1
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Unexpected Trends in the Stability and Dissociation Kinetics of Lanthanide(III) Complexes with Cyclen-Based Ligands across the Lanthanide Series

Zoltán Garda , Viktória Nagy , Aurora Rodríguez-Rodríguez , Rosa Pujales-Paradela , Véronique Patinec et al.

Inorganic Chemistry, 2020, 59 (12), pp.8184-8195. ⟨10.1021/acs.inorgchem.0c00520⟩

Article dans une revue hal-02564517v1
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High‐Field Detection of biomarkers with Fast Field‐Cycling MRI: The Example of Zinc Sensing

Markus Bödenler , Kyangwi Malikidogo , Jean-François Morfin , Christoph Aigner , Éva Tóth et al.

Chemistry - A European Journal, 2019, ⟨10.1002/chem.201901157⟩

Article dans une revue hal-02117697v1
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A biocompatible redox MRI probe based on a Mn( ii )/Mn( iii ) porphyrin

Sara Pinto , Mário Calvete , Mariana Ghica , Sérgio Soler , Iluminada Gallardo et al.

Dalton Transactions, 2019, 48 (10), pp.3249-3262. ⟨10.1039/c8dt04775h⟩

Article dans une revue hal-02071232v1
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Gadolinium Complexes of Highly Rigid, Open-Chain Ligands Containing a Cyclobutane Ring in the Backbone: Decreasing Ligand Denticity Might Enhance Kinetic Inertness

Oriol Porcar-Tost , Jose Olivares , Agnès Pallier , David Esteban-Gómez , Ona Illa et al.

Inorganic Chemistry, 2019, 58 (19), pp.13170-13183. ⟨10.1021/acs.inorgchem.9b02044⟩

Article dans une revue hal-02358960v1
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Responsive ParaCEST Contrast Agents

Éva Tóth , Celia ́ Bonnet

Inorganics, 2019, 7 (5), pp.68. ⟨10.3390/inorganics7050068⟩

Article dans une revue hal-02355925v1
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Des agents intelligents pour l’imagerie moléculaire

Éva Tóth

L'Actualité Chimique, 2019, 446, pp.11-17

Article dans une revue hal-03036754v1
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Toward MRI and Optical Detection of Zwitterionic Neurotransmitters: Near-Infrared Luminescent and Magnetic Properties of Macrocyclic Lanthanide(III) Complexes Appended with a Crown Ether and a Benzophenone Chromophore

Fatima Oukhatar , Svetlana Eliseeva , Celia ́ Bonnet , Matteo Placidi , Nikos Logothetis et al.

Inorganic Chemistry, 2019, 58 (20), pp.13619-13630. ⟨10.1021/acs.inorgchem.9b00887⟩

Article dans une revue hal-02355920v1
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Metal-based redox-responsive MRI contrast agents

Sara Pinto , Vanessa Tomé , Mário J.F. Calvete , M. Margarida C.A. Castro , Éva Tóth et al.

Coordination Chemistry Reviews, 2019, 390, pp.1-31. ⟨10.1016/j.ccr.2019.03.014⟩

Article dans une revue hal-02358923v1
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Luminescence Properties of Self-Aggregating TbIII-DOTA-Functionalized Calix[4]arenes

Florian Mayer , Sriram Tiruvadi Krishnan , Daniel Schühle , Svetlana Eliseeva , Stéphane Petoud et al.

Frontiers in Chemistry, 2018, 6, pp.1. ⟨10.3389/fchem.2018.00001⟩

Article dans une revue hal-02519038v1
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A Porphyrin Dimer–GdDOTA Conjugate as a Theranostic Agent for One- and Two-Photon Photodynamic Therapy and MRI

Julie Schmitt , Sébastien Jenni , Angélique Sour , Valérie Heitz , Frédéric Bolze et al.

Bioconjugate Chemistry, 2018, 29 (11), pp.3726-3738. ⟨10.1021/acs.bioconjchem.8b00634⟩

Article dans une revue hal-02071234v1
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Theranostics and Image Guided Drug Delivery. Edited by Maya Thanou

Sara Lacerda , Éva Tóth

ChemMedChem, 2018, 13 (17), pp.1851-1852. ⟨10.1002/cmdc.201800464⟩

Article dans une revue (compte-rendu de lecture) hal-01966410v1

A Bishydrated, Eight-Coordinate Gd(III) Complex with Very Fast Water Exchange: Synthesis, Characterization, and Phantom MR Imaging

Bedika Phukan , Kyangwi Malikidogo , Célia Bonnet , Éva Tóth , Samsuzzoha Mondal et al.

ChemistrySelect, 2018, 3 (27), pp.7668-7673. ⟨10.1002/slct.201801629⟩

Article dans une revue hal-02071241v1
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A cocktail of 165 Er( iii ) and Gd( iii ) complexes for quantitative detection of zinc using SPECT and MRI

Kyangwi Malikidogo , Isidro da Silva , Jean-François Morfin , Sara Lacerda , Laurent Barantin et al.

Chemical Communications, 2018, 54 (55), pp.7597 - 7600. ⟨10.1039/c8cc03407a⟩

Article dans une revue hal-01904447v1

Mn 2+ complexes of open-chain ligands with a pyridine backbone: less donor atoms lead to higher kinetic inertness

Sophie Laine , Célia Bonnet , Ferenc Kálmán , Zoltán Garda , Agnès Pallier et al.

New Journal of Chemistry, 2018, 42 (10), pp.8012-8020. ⟨10.1039/C8NJ00648B⟩

Article dans une revue hal-01966154v1

Functionalised Carbon Nanotubes Enhance Brain Delivery of Amyloid-Targeting Pittsburgh Compound B (PiB)-Derived Ligands

Pedro Miguel Costa , Julie Tzu-Wen Wang , Jean-François Morfin , Tamanna Khanum , Wan To et al.

Nanotheranostics, 2018, 2 (2), pp.168-183. ⟨10.7150/ntno.23125⟩

Article dans une revue hal-02080078v1
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Remarkable differences and similarities between the isomeric Mn(II)- cis - and trans- 1,2-diaminocyclohexane- N , N , N ′, N ′-tetraacetate complexes

Enikő Molnár , Balázs Váradi , Zoltán Garda , Richárd Botár , Ferenc Kálmán et al.

Inorganica Chimica Acta, 2018, 472, pp.254-263

Article dans une revue hal-02572224v1

Strategies for sensing neurotransmitters with responsive MRI contrast agents

Goran Angelovski , Éva Tóth

Chemical Society Reviews, 2017, 46 (2), pp.324 - 336. ⟨10.1039/C6CS00154H⟩

Article dans une revue hal-01632884v1

Next-Generation Magnetic Resonance Imaging Contrast Agents

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Inorganic Chemistry, 2017, 56 (11), pp.6029-6034. ⟨10.1021/acs.inorgchem.7b01277⟩

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Lanthanide Complexes in Molecular Magnetic Resonance Imaging and Theranostics

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ChemMedChem, 2017, 12 (12), pp.883 - 894. ⟨10.1002/cmdc.201700210⟩

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Metal complexes for multimodal imaging of misfolded protein-related diseases

S. Lacerda , J.-F. Morfin , C. F G C Geraldes , É. Tóth

Dalton Transactions, 2017, 46 (42), pp.14461-14474. ⟨10.1039/C7DT02371E⟩

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Mechanostereoselective One-Pot Synthesis of Functionalized Head-to-Head Cyclodextrin [3]Rotaxanes and Their Application as Magnetic Resonance Imaging Contrast Agents

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Organic Letters, 2017, 19 (5), pp.1136-1139. ⟨10.1021/acs.orglett.7b00153⟩

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Surface PEG Grafting Density Determines Magnetic Relaxation Properties of Gd-Loaded Porous Nanoparticles for MR Imaging Applications

Wuyuan Zhang , Jonathan Martinelli , Joop A. Peters , Jacob M.A. van Hengst , Hans Bouwmeester et al.

ACS Applied Materials & Interfaces, 2017, 9 (28), pp.23458 - 23465. ⟨10.1021/acsami.7b05912⟩

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Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting.

Jonathan Pansieri , Marie Plissonneau , Nathalie Stransky-Heilkron , Mireille Dumoulin , Laurence Heinrich-Balard et al.

Nanomedicine, 2017, 12 (14), pp.1675-1687. ⟨10.2217/nnm-2017-0079⟩

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Proton-exchange in a paramagnetic chemical exchange saturation transfer agent from experimental studies and ab initio metadynamics simulation

Rodolphe Pollet , Celia ́ Bonnet , Pascal ́ Retailleau , Philippe ́ Durand , Éva Tóth

Inorganic Chemistry, 2017, 56, pp.4317-4323. ⟨10.1021/acs.inorgchem.6b02773⟩

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Novel CDTA-based, Bifunctional Chelators for Stable and Inert Mn II Complexation: Synthesis and Physicochemical Characterization

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Inorganic Chemistry, 2017, 56 (14), pp.7746 - 7760. ⟨10.1021/acs.inorgchem.7b00460⟩

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Approaching the Kinetic Inertness of Macrocyclic Gadolinium(III)-Based MRI Contrast Agents with Highly Rigid Open-Chain Derivatives

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Chemistry - A European Journal, 2016, 22 (3), pp.896 - 901. ⟨10.1002/chem.201503836⟩

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Associating a negatively charged GdDOTA-derivative to the Pittsburgh compound B for targeting Aβ amyloid aggregates

André Martins , Alexandre Oliveira , Jean-François Morfin , Douglas Laurents , Éva Tóth et al.

Journal of Biological Inorganic Chemistry, 2016, 21 (1), pp.83-99. ⟨10.1007/s00775-015-1316-9⟩

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Smart Contrast Agents for Magnetic Resonance Imaging

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CHIMIA, 2016, 70 (1), pp.102 - 108. ⟨10.2533/chimia.2016.102⟩

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Prototypes of Lanthanide(III) Agents Responsive to Enzymatic Activities in Three Complementary Imaging Modalities: Visible/Near-Infrared Luminescence, PARACEST-, and T 1 -MRI

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Journal of the American Chemical Society, 2016, 138 (9), pp.2913 - 2916. ⟨10.1021/jacs.5b12084⟩

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Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting.

Marie Plissonneau , Jonathan Pansieri , Laurence Heinrich-Balard , Jean-François Morfin , Nathalie Stransky-Heilkron et al.

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The quest for biocompatible phthalocyanines for molecular imaging: Photophysics, relaxometry and cytotoxicity studies

Sara M.A. Pinto , Vanessa A. Tomé , Mário J.F. Calvete , Mariette M. Pereira , Hugh D. Burrows et al.

Journal of Inorganic Biochemistry, 2016, 154, pp.50 - 59. ⟨10.1016/j.jinorgbio.2015.10.013⟩

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pH-responsive relaxometric behaviour of coordination polymer nanoparticles made of a stable macrocyclic gadolinium macrocyclic chelate

J. Aríñez-Soriano , Albalad J. , Carné-Sánchez J. , Celia ́ Bonnet , Busqué C. S. et al.

Chemistry - A European Journal, 2016, 22 (37), pp.13162-13170. ⟨10.1002/chem.201602356⟩

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Gallium-68 Complexes Conjugated to Pittsburgh Compound B: Radiolabeling and Biological Evaluation

D Cressier , M Dhilly , Tt Cao Pham , F Fillesoye , F Gourand et al.

Molecular Imaging and Biology, 2016, 18 (3), pp.334-43. ⟨10.1007/s11307-015-0906-9⟩

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A Theranostic Agent Combining a Two-Photon-Absorbing Photosensitizer for Photodynamic Therapy and a Gadolinium(III) Complex for MRI Detection

Julie Schmitt , Valérie Heitz , Angélique Sour , Frédéric Bolze , Pascal Kessler et al.

Chemistry - A European Journal, 2016, 22 (8), pp.2775-2786. ⟨10.1002/chem.201503433⟩

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Four Gadolinium(III) Complexes Appended to a Porphyrin: A Water-Soluble Molecular Theranostic Agent with Remarkable Relaxivity Suited for MRI Tracking of the Photosensitizer

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Inorganic Chemistry, 2016, 55 (9), pp.4545 - 4554. ⟨10.1021/acs.inorgchem.6b00381⟩

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A pyridine-based ligand with two hydrazine functions for lanthanide chelation: remarkable kinetic inertness for a linear, bishydrated complex

Célia S. Bonnet , Sophie Laine , Frédéric Buron , Gyula Tircsó , Agnès Pallier et al.

Inorganic Chemistry, 2015, 54 (12), pp.5991-6003. ⟨10.1021/acs.inorgchem.5b00804⟩

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MRI Sensing of Neurotransmitters with a Crown Ether Appended Gd3+ Complex

Fatima Oukhatar , Sandra Même , William Même , Frédéric Szeremeta , Nikos K. Logothetis et al.

ACS Chemical Neuroscience, 2015, 6 (2), pp.219-225. ⟨10.1021/cn500289y⟩

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Macrocyclic Gd(3+) Complexes with Pendant Crown Ethers Designed for Binding Zwitterionic Neurotransmitters.

Fatima Oukhatar , Hervé Meudal , Céline Landon , Nikos K Logothetis , Carlos Platas-Iglesias et al.

Chemistry - A European Journal, 2015, 21 (31), pp.11226-11237

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H 4 octapa: Highly Stable Complexation of Lanthanide(III) Ions and Copper(II)

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Inorganic Chemistry, 2015, 54 (5), pp.2345-2356. ⟨10.1021/ic502966m⟩

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X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations

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Nano Research, 2015, 8 (7), pp.2373 - 2379. ⟨10.1007/s12274-015-0747-5⟩

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Stabilizing Divalent Europium in Aqueous Solution Using Size-Discrimination and Electrostatic Effects

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Inorganic Chemistry, 2015, 54 (10), pp.4940-4952. ⟨10.1021/acs.inorgchem.5b00548⟩

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Interaction of PiB-Derivative Metal Complexes with Beta-Amyloid Peptides: Selective Recognition of the Aggregated Forms

André F. Martins , David M. Dias , Jean-François Morfin , Sara Lacerda , Douglas V. Laurents et al.

Chemistry - A European Journal, 2015, 21 (14), pp.5413-5422. ⟨10.1002/chem.201406152⟩

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Nanozeolite-LTL with Gd(III) deposited in the large and Eu(III) in the small cavities as a magnetic resonance optical imaging probe.

Florian Mayer , Wuyuan Zhang , Thomas Brichart , Olivier Tillement , Célia S Bonnet et al.

Chemistry - A European Journal, 2014, 20 (12), pp.3358-3364. ⟨10.1002/chem.201304457⟩

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A bis(pyridine N-oxide) analogue of DOTA: relaxometric properties of the Gd(III) complex and efficient sensitization of visible and NIR-emitting lanthanide(III) cations including Pr(III) and Ho(III).

André F Martins , Svetlana V Eliseeva , Henrique F Carvalho , João M C Teixeira , Carlos T B Paula et al.

Chemistry - A European Journal, 2014, 20 (45), pp.14834-14845

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Gd(3+) complexes conjugated to Pittsburgh compound B: potential MRI markers of β-amyloid plaques.

André F Martins , Jean-François Morfin , Carlos F G C Geraldes , Éva Tóth

European Journal of Biochemistry, 2014, 19 (2), pp.281-295

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Mechanistic studies of Gd$^{3+}$-based MRI contrast agents for Zn$^{2+}$ detection: towards rational design

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Chemistry - A European Journal, 2014, 20 (35), pp.10959-10969. ⟨10.1002/chem.201403043⟩

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Cyclodextrin Polyrotaxanes as a Highly Modular Platform for the Development of Imaging Agents

Jean Wilfried Fredy , Jérémy Scelle , Aurélie Guenet , Elodie Morel , Ségolène Adam de beaumais et al.

Chemistry - A European Journal, 2014, 20 (35), pp.10915-10920. ⟨10.1002/chem.201403635⟩

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Agents de contraste pour l'IRM

Jean-François Morfin , Jean-Claude Beloeil , Éva Tóth

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Relaxometry Studies of a Highly Stable Nanoscale Metal–Organic Framework Made of Cu(II), Gd(III), and the Macrocyclic DOTP

Arnau Carné-Sánchez , Célia Bonnet , Inhar Imaz , Julia Lorenzo , Éva Tóth et al.

Journal of the American Chemical Society, 2013, 135 (47), pp.17711-17714. ⟨10.1021/ja4094378⟩

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Amide conjugates of the DO3A-N-(alpha-amino)propionate ligand: leads for stable, high relaxivity Contrast Agents for MRI?

M.F. Ferreira , A.F. Martins , C.I.O. Martins , É. Tóth , T.B. Rodrigues et al.

Contrast Media and Molecular Imaging, 2013, 8 (1), pp.40-49. ⟨10.1002/cmmi.1492⟩

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Lanthanide-Based, Near-Infrared Luminescent and Magnetic Lipoparticles: Monitoring Particle Integrity.

Sara Lacerda , Célia S Bonnet , Agnès Pallier , Sandrine Villette , Frédéric Foucher et al.

Small, 2013, 9 (16), pp.2662-2666. ⟨10.1002/smll.201201923⟩

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New tris-3,4-HOPO lanthanide complexes as potential imaging probes: complex stability and magnetic properties.

Ana Catarina Fernandes Mendonça , André F Martins , Andrea Melchior , Sérgio M Marques , Sílvia Chaves et al.

Dalton Transactions, 2013, 42 (17), pp.6046-57. ⟨10.1039/c2dt32237d⟩

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Radiolabeling and initial evaluation of [In-111]AML-1, a new probe for SPECT imaging of amyloid deposits

Nicolas Arlicot , Hélène Fourmy , Martin André , Johnny Vercouillie , Carlos Geraldes et al.

Journal of Labelled Compounds and Radiopharmaceuticals, 2013, 56 (supplément 1), pp.S307

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PiB-Conjugated, Metal-Based Imaging Probes: Multimodal Approaches for the Visualization of β-Amyloid Plaques

André F. Martins , Jean-François Morfin , Anna Kubícková , Vojtěch Kubícek , Frédéric Buron et al.

Planetary and Space Science, 2013, 4 (5), pp.436-440. ⟨10.1021/ml400042w⟩

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PiB-Conjugated, Metal-Based Imaging Probes: Multimodal Approaches for the Visualization of β-Amyloid Plaques

André Martins , Jean-François Morfin , Anna Kubíčková , Vojtěch Kubíček , Frédéric Buron et al.

ACS Medicinal Chemistry Letters, 2013, 4 (5), pp.436-440. ⟨10.1021/ml400042w⟩

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Thermodynamic stability and relaxation studies of small, triaza-macrocyclic Mn(II) chelates.

Arsénio de Sá , Célia S Bonnet , Carlos F G C Geraldes , Éva Tóth , Paula M T Ferreira et al.

Dalton Transactions, 2013, 42 (13), pp.4522-32. ⟨10.1039/c2dt32496b⟩

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Tris(phosphonomethyl)cyclen Derivatives: Thermodynamic Stability, Kinetics, Solution Structure, and Relaxivity of Ln3+ Complexes

L.M.P. Lima , R. Degaldo , P. Hermann , R. Sevcik , P. Lubal et al.

European Journal of Inorganic Chemistry, 2012, 2012 (15), pp.2548-2559. ⟨10.1002/ejic.201101335⟩

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Pyridine-based lanthanide complexes combining MRI and NIR luminescence activities.

Célia S Bonnet , Frédéric Buron , Fabien Caillé , Chad M Shade , Bohuslav Drahoš et al.

Chemistry - A European Journal, 2012, 18 (5), pp.1419-31. ⟨10.1002/chem.201102310⟩

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Lanthanide Complexes Formed with the Tri- and Tetraacetate Derivatives of Bis(aminomethyl)phosphinic Acid: Equilibrium, Kinetic and NMR Spectroscopic Studies

Gyula Tircsó , Ferenc Kálmán , Robert Pal , István Bányai , Tamas Varga et al.

European Journal of Inorganic Chemistry, 2012, 2012 (12), pp.2062-2073. ⟨10.1002/ejic.201101299⟩

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Lanthanide complexes based on a diazapyridinophane platform containing picolinate pendants.

Adrián Roca-Sabio , Célia S Bonnet , Marta Mato-Iglesias , David Esteban-Gómez , Éva Tóth et al.

Inorganic Chemistry, 2012, 51 (20), pp.10893-10903. ⟨10.1021/ic301369z⟩

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Lanthanide(III) complexes that contain a self-immolative arm: potential enzyme responsive contrast agents for magnetic resonance imaging.

Thomas Chauvin , Susana Torres , Renato Rosseto , Jan Kotek , Bernard Badet et al.

Chemistry - A European Journal, 2012, 18 (5), pp.1408-18. ⟨10.1002/chem.201101779⟩

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Isoquinoline-based lanthanide complexes: bright NIR optical probes and efficient MRI agents.

Fabien Caillé , Célia S Bonnet , Frédéric Buron , Sandrine Villette , Lothar Helm et al.

Inorganic Chemistry, 2012, 51 (4), pp.2522-32. ⟨10.1021/ic202446e⟩

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Manganese(II) Complexes as Potential Contrast Agents for MRI

Bohuslav Drahos , Ivan Lukes , Éva Tóth

European Journal of Inorganic Chemistry, 2012, 12 (SI), pp.1975-1986. ⟨10.1002/ejic.201101336⟩

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Mn2+ complexes of 1-oxa-4,7-diazacyclononane based ligands with acetic, phosphonic and phosphinic acid pendant arms: Stability and relaxation studies

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Dalton Transactions, 2011, 40 (39), pp.10131. ⟨10.1039/C1DT10543D⟩

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Kinetics of Ga(NOTA) formation from weak Ga-citrate complexes.

Jean-François Morfin , Éva Tóth

Inorganic Chemistry, 2011, 50 (20), pp.10371-8. ⟨10.1021/ic201445e⟩

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Efficient Access to C1-and C3-Functionalized Isoquinolines: Towards Potential Lanthanide Ligands

Fabien Caille , Frederic Buron , Éva Tóth , Franck Suzenet

European Journal of Organic Chemistry, 2011, 11, pp.2120-2127. ⟨10.1002/ejoc.201001691⟩

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Influence of calcium-induced aggregation on the sensitivity of aminobis(methylenephosphonate)-containing potential MRI contrast agents.

Jörg Henig , Ilgar Mamedov , Petra Fouskova , Éva Tóth , Nikos K Logothetis et al.

Inorganic Chemistry, 2011, 50 (14), pp.6472-81. ⟨10.1021/ic1024235⟩

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Mn2+ complexes with 12-membered pyridine based macrocycles bearing carboxylate or phosphonate pendant arm: crystallographic, thermodynamic, kinetic, redox, and 1H/17O relaxation studies.

Bohuslav Drahoš , Jan Kotek , Ivana Císařová , Petr Hermann , Lothar Helm et al.

Inorganic Chemistry, 2011, 50 (24), pp.12785-801. ⟨10.1021/ic201935r⟩

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A Pyrophosphate-Responsive Gadolinium(III) MRI Contrast Agent

Andrew J. Surman , Celia S. Bonnet , Mark P. Lowe , Gavin D. Kenny , Jimmy D. Bell et al.

Chemistry - A European Journal, 2011, 17 (1), pp.223-230. ⟨10.1002/chem.201001397⟩

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Lanthanide complexes as imaging agents anchored on nano-sized particles of boehmite

Estefania Delgado-Pinar , M. Teresa Albelda , Juan C. Frias , Olga Barreiro , Emilio Tejera et al.

Dalton Transactions, 2011, 40 (24), pp.6451-6457. ⟨10.1039/c1dt10389j⟩

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Dissociation kinetics of Mn2+ complexes of NOTA and DOTA

Bohuslav Drahoš , Vojtěch Kubíček , Celia ́ Bonnet , Petr Hermann , Ivan Lukeš et al.

Dalton Transactions, 2011, 40 (9), pp.1945. ⟨10.1039/c0dt01328e⟩

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Calcium-responsive paramagnetic CEST agents

Goran Angelovski , Thomas Chauvin , Rolf Pohmann , Nikos K. Logothetis , Éva Tóth

Bioorganic and Medicinal Chemistry, 2011, 19 (3), pp.1097-1105. ⟨10.1016/j.bmc.2010.07.023⟩

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Macrocyclic Receptor Showing Extremely High Sr(II)/Ca(II) and Pb(II)/Ca(II) Selectivities with Potential Application in Chelation Treatment of Metal Intoxication

Raquel Ferreiros-Martinez , David Esteban-Gomez , Éva Tóth , Blas Andres De , Carlos Platas-Iglesias et al.

Inorganic Chemistry, 2011, 50 (8), pp.3772-3784. ⟨10.1021/ic200182e⟩

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Synthesis, Characterization and Biological Evaluation of In(III) Complexes Anchored by DOTA-like Chelators Bearing a Quinazoline Moiety

Raquel Garcia , Vojtech Kubicek , Bohuslav Drahos , Lurdes Gano , Isabel C. Santos et al.

Mettalomics, 2010, 2 (8), pp.571-580. ⟨10.1039/c004797j⟩

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Molecular Recognition of Sialic Acid by Lanthanide(III) Complexes through Cooperative Two-Site Binding

Martin Regueiro-Figueroa , Kristina Djanashvili , David Esteban-Gomez , Thomas Chauvin , Éva Tóth et al.

Inorganic Chemistry, 2010, 49 (9), pp.4212-4223. ⟨10.1021/ic902461g⟩

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Hydrophobic chromophore cargo in micellar structures: a different strategy to sensitize lanthanide cations

Célia Bonnet , Laurent Pellegatti , Frédéric Buron , Chad Shade , Sandrine Villette et al.

Chemical Communications, 2010, 46 (1), pp.124-126. ⟨10.1039/B918881A⟩

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Welcome to ‘Molecular Probes in Optical and Magnetic Resonance Imaging’

Éva Tóth , Stéphane Petoud

Future Medicinal Chemistry, 2010, 2 (3), pp.305-306. ⟨10.4155/fmc.10.7⟩

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Macrocyclic Gd3+ Chelates Attached to a Silsesquioxane Core as Potential MRI Contrast Agents - Synthesis, Physicochemical Characterization and Stability Studies

Jorg Henig , Éva Tóth , Jorn Engelmann , Sven Gottschalk , Hermann A. Mayer

Inorganic Chemistry, 2010, 49 (13), pp.6124-6138. ⟨10.1021/ic1007395⟩

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Lanthanide(III) complexes of 4,10-bis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane-1,7-diacetic acid (trans-H6do2a2p) in solution and in the solid state: structural studies along the series

Paula c. M. Campello , Sara Lacerda , Isabel c. Santos , Giovannia a. Pereira , Carlos F. G. C. Geraldes et al.

Chemistry - A European Journal, 2010, 16 (28), pp.8446-8465. ⟨10.1002/chem.201000320⟩

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Smart MR Imaging Agents Relevant to Potential Neurologic Applications

Célia Bonnet , Éva Tóth

American Journal of Neuroradiology, 2010, 31 (3), pp.401-409. ⟨10.3174/ajnr.A1753⟩

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Gallium(III) Complexes of DOTA and DOTA-Monoamide: Kinetic and Thermodynamic Studies

Vojtech Kubicek , Jana Havlickova , Jan Kotek , Tircso Gyula , Petr Hermann et al.

Inorganic Chemistry, 2010, 49 (23), pp.10960-10969. ⟨10.1021/ic101378s⟩

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Towards highly efficient, intelligent and bimodal imaging probes : novel approaches provided by lanthanide coordination chemistry

Célia Bonnet , Éva Tóth

Comptes Rendus. Chimie, 2010, 13 (6-7 Sp. Iss. SI), pp.700-714. ⟨10.1016/j.crci.2010.03.026⟩

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Densely packed Gd(III)-chelates with fast water exchange on a calix[4]arene scaffold: a potential MRI contrast agent

Daniel T. Schuhle , Miloslav Polasek , Ivan Lukes , Thomas Chauvin , Éva Tóth et al.

Dalton Transactions, 2010, 39 (1), pp.185-191. ⟨10.1039/b917673j⟩

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Magnetic resonance imaging probes for sensing biologically relevant metal ions

Célia Bonnet , Éva Tóth

Future Medicinal Chemistry, 2010, 2 (3), pp.367-384. ⟨10.4155/fmc.09.161⟩

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Mn2+ Complexes with Pyridine-Containing 15-Membered Macrocycles : Thermodynamic, Kinetic, Crystallographic, and H-1/O-17 Relaxation Studies

Bohuslav Drahos , Jan Kotek , Petr Hermann , Ivan Lukes , Éva Tóth

Inorganic Chemistry, 2010, 49 (7), pp.3224-3238. ⟨10.1021/ic9020756⟩

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Ga(III) complexes with DOTA-like ligand - thermodynamic and kinetic stability

Vojtech Kubicek , Petr Hermann , Eva Jakab-Toth

Nuclear Medicine and Biology, 2010, 37 (6), pp.680-680. ⟨10.1016/j.nucmedbio.2010.04.192⟩

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Relaxation and luminescence studies on hydrated bipyridyl- and terpyridyl-based lanthanide complexes

Vojtech Kubicek , Anna Hamplova , Laurence Maribe , Samir Mameri , Raymond Ziessel et al.

Dalton Transactions, 2009, 43, pp.9466-9474. ⟨10.1039/b913084e⟩

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Stability, Water Exchange, and Anion Binding Studies on Lanthanide(III) Complexes with a Macrocyclic Ligand Based on 1,7-Diaza-12-crown-4: Extremely Fast Water Exchange on the Gd3+ Complex

Zoltan Palinkas , Adrian Roca-Sabio , Marta Mato-Iglesias , David Steban-Gomez , Carlos Platas-Iglesias et al.

Inorganic Chemistry, 2009, 48 (18), pp.8878-8889. ⟨10.1021/ic9011197⟩

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Design and function of metal complexes as contrast agents in MRI

Vojtech Kubicek , Éva Tóth

Advances in Inorganic Chemistry, 2009, 61, pp.63-129. ⟨10.1016/S0898-8838(09)00202-5⟩

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Gd(DO3A-N-alpha-aminopropionate): a versatile and easily available synthon with optimized water exchange for the synthesis of high relaxivity, targeted MRI contrast agents

Miguel Ferreira , Andre Martins , A. Martins Jose , Paula Ferreira , Éva Tóth et al.

Chemical Communications, 2009, 42, pp.6475-6477. ⟨10.1039/b912201j⟩

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A novel tetraazamacrocycle bearing a thiol pendant arm for labeling biomolecules with radiolanthanides

Sara Lacerda , M. Paula Campello , Fernanda Marques , Lurdes Gano, , Vojtech Kubicek et al.

Dalton Transactions, 2009, 23, pp.4509-4518. ⟨10.1039/b820375j⟩

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A quinazoline-derivative DOTA-type gallium(III) complex for targeting epidermal growth factor receptors: synthesis, characterisation and biological studies

Raque Garcia , Petra Fousková , Lurdes Gano , Antonio Paulo , Paula Campello et al.

Journal of Biological Inorganic Chemistry, 2009, 14 (2), pp.261-271. ⟨10.1007/s00775-008-0446-8⟩

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Macrocyclic Receptor Exhibiting Unprecedented Selectivity for Light Lanthanides

Adrian Roca-Sabio , Marta Mato-Iglesias , David Esteban-Gomez , Éva Tóth , Andres de Blas et al.

Journal of the American Chemical Society, 2009, 131 (9), pp.3331-3341. ⟨10.1021/ja808534w⟩

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Smart magnetic resonance imaging agents that sense extracellular calcium fluctuations

Goran Angelovski , Petra Fouskova , Ilgar Mamedov , Santiago Canals , Éva Tóth et al.

ChemBioChem, 2008, 9 (11), pp.1729-34. ⟨10.1002/cbic.200800165⟩

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Detection of enzymatic activity by PARACEST MRI: a general approach to target a large variety of enzymes

Thomas Chauvin , Philippe Durand , Michèle Bernier , Hervé Meudal , Bich-Thuy Doan et al.

Angewandte Chemie International Edition, 2008, 47 (23), pp.4370-4372. ⟨10.1002/anie.200800809⟩

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Lanthanide complexes based on a 1,7-diaza-12-crown-4 platform containing picolinate pendants: A new structural entry for the design of magnetic resonance imaging contrast agents

M. Mato-Iglesias , A. Roca-Sabio , Z. Palinkas , D. Esteban-Gomez , C. Platas-Iglesias et al.

Inorganic Chemistry, 2008, 47 (17), pp.7840-7851. ⟨10.1021/ic800878x⟩

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Facile Synthesis and Relaxation Properties of Novel Bis-polyazamacrocyclic Gd3+ Complexes: an Attempt towards Calcium Sensitive MRI Contrast Agents

Anurag Mishra , Petra Fousková , Goran Angelovski , Edina Balogh , Anil K. Mishra et al.

Inorganic Chemistry, 2008, 47 (4), pp.1370-1381. ⟨10.1021/ic7017456⟩

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Pyridine-based lanthanide complexes: towards bimodal agents operating as near infrared luminescent and MRI reporters

L. Pellegatti , J. Zhang , B. Drahos , Sandrine Villette , Franck Suzenet et al.

Chemical Communications, 2008, 48CONTRAST AGENTS; LIGANDS; RATES; IONS; ACID, pp.6591-6593. ⟨10.1039/b817343e⟩

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Gadonanotubes as Ultrasensitive pH-Smart Probes for Magnetic Resonance Imaging

Keith B. Hartman , Sabrina Laus , Robert D. Bolskar , Raja Muthupillai , Lothar Helm et al.

Nano Letters, 2008, 8 (2), pp.415-419. ⟨10.1021/nl0720408⟩

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Gd(III)-EPTPAC(16), a new self-assembling potential liver MRI contrast agent: in vitro characterization and in vivo animal imaging studies

Suzana Torres , M.I.M. Prata , Ana Santos , Joao P. Andre , Jose A. Martins et al.

NMR in Biomedicine, 2008, 21 (4), pp.322-336. ⟨10.1002/nbm.1194⟩

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A benzene-core trinuclear GdIII complex: towards the optimization of relaxivity for MRI contrast agent applications at high magnetic field

João Bruno Livramento , Lothar Helm , Angélique Sour , Conlin O'Neil , André E. Merbach et al.

Dalton Transactions, 2008, 9, pp.1195-1202. ⟨10.1039/b717390c⟩

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Noncovalent Functionalization of Carbon Nanotubes with Amphiphilic Gd3+ Chelates: Towards Powerful T1 and T2 MRI

Cyrille Richard , Bich-Thuy Doan , Jean-Claude Beloeil , Michel Bessodes , Éva Tóth et al.

Nano Letters, 2008, 8 (1), pp.232-236. ⟨10.1021/nl072509z⟩

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In vivo MRI assessment of a novel GdIII-based contrast agent designed for high magnetic field applications

Paulo Loureiro de Sousa , João Bruno Livramento , Lothar Helm , André E Merbach , William Même et al.

Contrast Media and Molecular Imaging, 2008, 3 (2), pp.78 - 85. ⟨10.1002/cmmi.233⟩

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Lanthanide-Based Conjugates as Polyvalent Probes for Biological Labeling

Stéphanie Claudel-Gillet , Jérôme Steibel , Nicolas Weibel , Thomas Chauvin , Marc Port et al.

European Journal of Inorganic Chemistry, 2008, 18, pp.2856 - 2862. ⟨10.1002/ejic.200800269⟩

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Towards extracellular Ca2+ sensing by MRI: synthesis and calcium-dependent 1H and 17O relaxation studies of two novel bismacrocyclic Gd3+ complexes

Kirti Dhingra , Petra Fousková , Goran Angelovski , Martin E. Maier , Nikos K. Logothetis et al.

Journal of Biological Inorganic Chemistry, 2008, 13 (1), pp.35-46. ⟨10.1007/s00775-007-0296-9⟩

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Detection of Enzymatic Activity by PARACEST MRI: A General Approach to Target a Large Variety of Enzymes

Thomas Chauvin , Philippe Durand , Michèle Bernier , Hervé Meudal , Bich-Thuy Doan et al.

Angewandte Chemie International Edition, 2008, 47 (23), pp.4370-4372. ⟨10.1002/anie.200800809⟩

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Dinuclear Complexes Formed with the Triazacyclononane Derivative ENOTA4-. High Pressure 17O NMR evidence of an associative water exchange on [MnII2(ENOTA)(H2O)2]

E. Balogh , Z. He , W. Hsieh , S. Liu , Éva Tóth

Inorganic Chemistry, 2007, 46 (1), pp.238-250

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Monopropionate analogues of DOTA4– and DTPA5–: kinetics of formation and dissociation of their lanthanide(iii) complexes

Edina Balogh , Raphaël Tripier , Petra Fousková , Felipe Reviriego , Henri Handel et al.

Dalton Transactions, 2007, 32, ⟨10.1039/B706353A⟩

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H5EPTPACH2OH: Synthesis, relaxometric characterization and H-1 NMR studies of the solution dynamics of its Ln(III) complexes

Ja. Martins , Jp. André , Ga. Pereira , R. Kiraly , E. Brücher et al.

European Journal of Inorganic Chemistry, 2007, 35, pp.5489-5499. ⟨10.1002/ejic.200700435⟩

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Gadolinium(III) Complexes of Mono- and Diethyl Esters of Monophosphonic Acid Analogue of DOTA as Potential MRI Contrast Agents: Solution Structures and Relaxometric Studies

P. Lebduskova , P. Hermann , L. Helm , É. Tóth , J. Kotek et al.

Dalton Transactions, 2007, 4, pp.493-501. ⟨10.1039/b612876a⟩

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Physicochemical and MR imaging characterisation of Gd3+ loaded PAMAM and hyperbranched dendrimers

Z. Jászberényi , L. Moriggi , P. Schmidt , C. Weidensteiner , R. Kneuer et al.

Journal of Biological Inorganic Chemistry, 2007, 12, pp.406-420

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Understanding paramagnetic relaxation phenomena in water-soluble gadofullerenes

S. Laus , B. Sitharaman , É. Tóth , Rd. Bolskar , Lm. Helm et al.

The Journal of physical chemistry, 2007, 111 (15), pp.5633-5639

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Phosphinic derivative of DTPA conjugated to a G5 PAMAM dendrimer: an (17)O and (1)H relaxation study of its Gd(iii) complex

P. Lebdušková , A. Sour , L. Helm , É. Tóth , J. Kotek et al.

Dalton Transactions, 2006, 28, pp.3399-3406. ⟨10.1039/b517847a⟩

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Supramolecular Assembly of an Amphiphilic GdIII Chelate: Tuning the Reorientational Correlation Time and the Water Exchange Rate

Susana Torres , José Lauro Martins , João André , Carlos Geraldes , A.E Merbach et al.

Chemistry - A European Journal, 2006, 12 (3), pp.940-948. ⟨10.1002/chem.200500551⟩

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Pyridine and phosphonate containing acyclic ligands for stable lanthanide complexation. Extremely fast water exchange on the GdIII chelates.

E. Balogh , M. Mato-Iglesias , C. Platas-Iglesias , É. Tóth , K. Djanashvili et al.

Inorganic Chemistry, 2006, 45 (21), pp.8719-8728. ⟨10.1021/ic0604157S0020-1669(06)00415-0⟩

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Positively charged GdIII cryptates: slow, associative water exchange

László Burai , Éva Tóth , Hervé Bazin , Meriem Benmelouka , Zoltán Jászberényi et al.

Dalton Transactions, 2006, 28 (4), pp.629-634. ⟨10.1039/b506700f⟩

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A Starburst-Shaped Heterometallic Compound Incorporating Six Densely Packed Gd3+ Ions

João Bruno Livramento , Angélique Sour , Alain Borel , André Merbach , Éva Tóth

Chemistry - A European Journal, 2006, 12 (4), pp.989-1003. ⟨10.1002/chem.200500969⟩

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First in vivo MRI assessment of a self-assembled metallostar compound endowed with a remarkable high field relaxivity

J.B. Livramento , C. Weidensteiner , M.I.M. Prata , P.R. Allegrini , Geraldes C.F.G.C. et al.

Contrast Media and Molecular Imaging, 2006, 1, pp.30-39. ⟨10.1002/cmmi.92⟩

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Unexpected Aggregation of Neutral, Xylene-Cored Dinuclear Gd(III) Chelates in Aqueous Solution

Jérôme Costa , Edina Balogh , Véronique Turcry , Raphaël Tripier , Michel Le Baccon et al.

Chemistry - A European Journal, 2006, 12 (26), pp.6841 - 6851. ⟨10.1002/chem.200501335⟩

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Pyridine and phosphonate containing ligands for stable lanthanide complexation. An experimental and theoretical study to assess the solution structure

M. Mato-Iglesias , E. Balogh , C. Platas-Iglesias , É. Tóth , A. de Blas et al.

Dalton Transactions, 2006, 45, pp.5404-5415. ⟨10.1039/b611544f⟩

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Fine-tuning water exchange on GdIII poly(amino carboxylates) by modulation of steric crowding

Zoltán Jászberényi , Angélique Sour , Éva Tóth , Meriem Benmelouka , André Merbach

Dalton Transactions, 2005, 16, pp.2713. ⟨10.1039/b506702b⟩

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Synthesis and complexation properties of DTPA-N,N″-bis[bis(n-butyl)]-N′-methyl-tris(amide). Kinetic stability and water exchange of its Gd 3+ complex

Z. Jászberényi , É. Tóth , T. Kálai , R. Király , L. Burai et al.

Dalton Transactions, 2005, 4, pp.694-701. ⟨10.1039/b417272h⟩

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Superparamagnetic gadonanotubes are high-performance MRI contrast agents

Balaji Sitharaman , Kyle Kissell , Keith Hartman , Lesa Tran , Andrei Baikalov et al.

Chemical Communications, 2005, 31, pp.3915. ⟨10.1039/b504435a⟩

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Kinetics of formation and dissociation of lanthanide(III) complexes with the 13-membered macrocyclic ligand TRITA

E. Balogh , Raphaël Tripier , R. Ruloff , É. Tóth

Dalton Transactions, 2005, 6, pp.1058-1065. ⟨10.1039/b418991d⟩

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Water-Soluble Gadofullerenes: Toward High-Relaxivity, pH-Responsive MRI Contrast Agents

Éva Tóth , Robert Bolskar , Alain Borel , Gabriel Gonzalez , Lothar Helm et al.

Journal of the American Chemical Society, 2005, 127 (2), pp.799-805. ⟨10.1021/ja044688h⟩

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Dinuclear, Bishydrated Gd III Polyaminocarboxylates with a Rigid Xylene Core Display Remarkable Proton Relaxivities

Jérôme Costa , Éva Tóth , Lothar Helm , André Merbach

Inorganic Chemistry, 2005, 44 (13), pp.4747-4755. ⟨10.1021/ic0500309⟩

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Destroying Gadofullerene Aggregates by Salt Addition in Aqueous Solution of Gd@C 60 (OH) x and Gd@C 60 [C(COOH 2 )] 10

Sabrina Laus , Balaji Sitharaman , Éva Tóth , Robert Bolskar , Lothar Helm et al.

Journal of the American Chemical Society, 2005, 127 (26), pp.9368-9369. ⟨10.1021/ja052388+⟩

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NMR relaxivity of Ln3+-based zeolite-type materials

G. Pereira , D. Ananias , J. Rocha , V. Amaral , R. Muller et al.

Journal of Materials Chemistry, 2005, 15 (35-36), pp.3832-3837. ⟨10.1039/B504082E⟩

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Rotational Dynamics Account for pH-Dependent Relaxivities of PAMAM Dendrimeric, Gd-Based Potential MRI Contrast Agents

Sabrina Laus , Angélique Sour , Robert Ruloff , Éva Tóth , André Merbach

Chemistry - A European Journal, 2005, 11 (10), pp.3064-3076. ⟨10.1002/chem.200401326⟩

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The highest water exchange rate ever measured for a Gd(iii) chelate

Marta Mato-Iglesias , Carlos Platas-Iglesias , Kristina Djanashvili , Joop Peters , Éva Tóth et al.

Chemical Communications, 2005, 37, pp.4729. ⟨10.1039/b508180g⟩

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Separation and Characterization of the Two Diastereomers for [Gd(DTPA-bz-NH 2 )(H 2 O)] 2- , a Common Synthon in Macromolecular MRI Contrast Agents: Their Water Exchange and Isomerization Kinetics

László Burai , Éva Tóth , Angélique Sour , André Merbach

Inorganic Chemistry, 2005, 44 (10), pp.3561-3568. ⟨10.1021/ic048645d⟩

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High Relaxivity Confined to a Small Molecular Space: A Metallostar-Based, Potential MRI Contrast Agent

João Bruno Livramento , Éva Tóth , Angélique Sour , Alain Borel , André Merbach et al.

Angewandte Chemie International Edition, 2005, 44 (10), pp.1480-1484. ⟨10.1002/anie.200461875⟩

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Lanthanide(III) Chelates of DTPA Bis(amide) Glycoconjugates: Potential Imaging Agents Targeted at the Asyaloglycoprotein Receptor

Paula Baía , João André , Carlos Geraldes , José Lauro Martins , André Merbach et al.

European Journal of Inorganic Chemistry, 2005, 2005 (11), pp.2110-2119. ⟨10.1002/ejic.200400766⟩

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Enhanced imaging properties of a GdIII complex with unusually large relaxivity

Nicolas Fatin-Rouge , Éva Tóth , Réto Meuli , Jean-Claude Bunzli

Journal of Alloys and Compounds, 2004, 374 (1-2), pp.298-302. ⟨10.1016/j.jallcom.2003.11.125⟩

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Lanthanide( III ) Complexes of DOTA-Glycoconjugates: A Potential New Class of Lectin-Mediated Medical Imaging Agents

João André , Carlos Geraldes , José Lauro Martins , André Merbach , Maria Prata et al.

Chemistry - A European Journal, 2004, 10 (22), pp.5804-5816. ⟨10.1002/chem.200400187⟩

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HPLC separation of diastereomers of Ln III -ethylenepropylene-triamine-pentaacetate complexes. Direct assessment of their water exchange rate

László Burai , Éva Tóth , André Merbach

Chemical Communications, 2003, 21, pp.2680-2681. ⟨10.1039/B308253A⟩

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GdIII Complexes with Fast Water Exchange and High Thermodynamic Stability: Potential Building Blocks for High-Relaxivity MRI Contrast Agents

Sabrina Laus , Robert Ruloff , Éva Tóth , André Merbach

Chemistry - A European Journal, 2003, 9 (15), pp.3555-3566. ⟨10.1002/chem.200204612⟩

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Novel macrocyclic EuII complexes: fast water exchange related to an extreme metal-coordinated water oxygen distance

L Burai , Éva Tóth , G. Moreau , Angélique Sour , R. Scopelliti et al.

Chemistry - A European Journal, 2003, ⟨10.1002/chem.200390159⟩

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Stability, structure and dynamics of cationic lanthanide(iii) complexes of N,N′-bis(propylamide)ethylenediamine-N,N′-diacetic acid

Carlos Platas-Iglesias , Daniele Corsi , Luce Vander Elst , Robert Müller , Daniel Imbert et al.

Dalton Transactions, 2003, 4, pp.727-737. ⟨10.1039/B211060A⟩

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Accelerating water exchange for GdIII chelates by steric compression around the water binding site.

Robert Ruloff , Éva Tóth , Rosario Scopelliti , Raphaël Tripier , Henri Handel et al.

Chemical Communications, 2002, 22, pp.2630-1

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From monomers to micelles: investigation of the parameters influencing proton relaxivity.

Gaëlle Nicolle , Éva Tóth , Klaus-Peter Eisenwiener , Helmut Mäcke , André Merbach

Journal of Biological Inorganic Chemistry, 2002, 7 (7-8), pp.757-69. ⟨10.1007/s00775-002-0353-3⟩

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EuII-cryptate with optimal water exchange and electronic relaxation: a synthon for potential pO2 responsive macromolecular MRI contrast agents.

László Burai , Rosario Scopelliti , Éva Tóth

Chemical Communications, 2002, 20, pp.2366-7

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The impact of rigidity and water exchange on the relaxivity of a dendritic MRI contrast agent.

Gaëlle Nicolle , Éva Tóth , Heribert Schmitt-Willich , Bernd Radüchel , André Merbach

Chemistry - A European Journal, 2002, 8 (5), pp.1040-8. ⟨10.1002/1521-3765(20020301)8:5<1040::AID-CHEM1040>3.0.CO;2-D⟩

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Lipari-Szabo approach as a tool for the analysis of macromolecular gadolinium(III)-based MRI contrast agents illustrated by the [Gd(EGTA-BA-(CH2)12)]nn+ polymer.

A Dunand , Éva Tóth , R Hollister , A Merbach

Journal of Biological Inorganic Chemistry, 2001, 6 (3), pp.247-55

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First solvation shell of the Cu(II) aqua ion: evidence for fivefold coordination.

A. Pasquarello , P Petri , P Salmon , O. Parisel , R. Car et al.

Science, 2001, 291 (5505), pp.856-9. ⟨10.1126/science.291.5505.856⟩

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Similarities and differences between the isoelectronic GdIII and EuII complexes with regard to MRI contrast agent applications

Éva Tóth , László Burai , André Merbach

Coordination Chemistry Reviews, 2001, 216-217, pp.363-382. ⟨10.1016/S0010-8545(01)00312-5⟩

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EPR on aqueous Gd3+ complexes and a new analysis method considering both line widths and shifts

Alain Borel , Éva Tóth , András Jánossy , Andre´ Merbach

Physical Chemistry Chemical Physics, 2000, 2 (6), pp.1311-1317. ⟨10.1039/A909553E⟩

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Equilibria and formation kinetics of some cyclen derivative complexes of lanthanides

Erika Szilágyi , Éva Tóth , Zoltán Kovács , Johannes Platzek , Bernd Radüchel et al.

Inorganica Chimica Acta Reviews, 2000, 298 (2), pp.226-234. ⟨10.1016/S0020-1693(99)00467-3⟩

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Solution and Solid-State Characterization of EuII Chelates: A Possible Route Towards Redox Responsive MRI Contrast Agents

László Burai , Éva Tóth , Sabine Seibig , Rosario Scopelliti , André Merbach

Chemistry - A European Journal, 2000, 6 (20), pp.3761-3770. ⟨10.1002/1521-3765(20001016)6:20<3761::AID-CHEM3761>3.0.CO;2-6⟩

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Spectroscopic Study of the Hydration Equilibria and Water Exchange Dynamics of Lanthanide(III) Complexes of 1,7-bis(carboxymethyl)-1,4,710-tetraazacyclododecane (DO2A)

Fabrice Yerly , Franck A. Dunand , Éva Tóth , Arthur Figueirinha , Zoltan Kovacs et al.

European Journal of Inorganic Chemistry, 2000, pp.1001-1006

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Unexpected Differences in the Dynamics and in the Nuclear and Electronic Relaxation Properties of the Isoelectronic [Eu II (DTPA)(H 2 O)] 3 - and [Gd III (DTPA)(H 2 O)] 2 - Complexes (DTPA = Diethylenetriamine Pentaacetate) 1

Sabine Seibig , Éva Tóth , André Merbach

Journal of the American Chemical Society, 2000, 122 (24), pp.5822-5830. ⟨10.1021/ja9937829⟩

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Lanthanide Podates with Programmed Intermolecular Interactions: Luminescence Enhancement through Association with Cyclodextrins and Unusually Large Relaxivity of the Gadolinium Self-Aggregates

Nicolas Fatin-Rouge , Éva Tóth , Didier Perret , Robin Backer , André Merbach et al.

Journal of the American Chemical Society, 2000, 122 (44), pp.10810-10820. ⟨10.1021/ja001089b⟩

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Mono- and bimetallic lanthanide(III) phenolic cryptates obtained by template reaction: solid state structure, photophysical properties and relaxivity †

Carlos Platas , Fernando Avecilla , Andrés de Blas , Teresa Rodríguez-Blas , Carlos Geraldes et al.

Journal of the Chemical Society Dalton Transactions, 2000, 4, pp.611-618. ⟨10.1039/A906675F⟩

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High Relaxivity for Monomeric Gd(DOTA)-Based MRI Contrast Agents, Thanks to Micellar Self-Organization

João André , Éva Tóth , Holger Fischer , Anna Seelig , Helmut Mäcke et al.

Chemistry - A European Journal, 1999, 5 (10), pp.2977-2983. ⟨10.1002/(SICI)1521-3765(19991001)5:10<2977::AID-CHEM2977>3.0.CO;2-T⟩

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Gd(DTPA-bisamide)alkyl Copolymers: A Hint for the Formation of MRI Contrast Agents with Very High Relaxivity

Éva Tóth , Lothar Helm , Kenneth Kellar , André Merbach

Chemistry - A European Journal, 1999, 5 (4), pp.1202-1211. ⟨10.1002/(SICI)1521-3765(19990401)5:4<1202::AID-CHEM1202>3.0.CO;2-Y⟩

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Lanthanide(III)–1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid complexes in acidic medium: significant decrease in water exchange rate

Erika Szilágyi , Éva Tóth , Ernö Brücher , André Merbach

Journal of the Chemical Society Dalton Transactions, 1999, 15, pp.2481-2486. ⟨10.1039/A903379C⟩

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Nuclear and Electronic Relaxation of Eu 2+ ( a q) : An Extremely Labile Aqua Ion 1

Peter Caravan , Éva Tóth , Antal Rockenbauer , André Merbach

Journal of the American Chemical Society, 1999, 121 (44), pp.10403-10409. ⟨10.1021/ja992264v⟩

Article dans une revue istex hal-02080885v1

Synthesis and physicochemical characterization of a novel precursor for covalently bound macromolecular MRI contrast agents.

J.P. André , H Maecke , Éva Tóth , A Merbach

Journal of Biological Inorganic Chemistry, 1999, 4 (3), pp.341-7

Article dans une revue hal-02080902v1

Coordination equilibrium— a clue for fast water exchange on potential magnetic resonance imaging contrast agents?

Éva Tóth , Orla Dhubhghaill , Ghislaine Besson , Lothar Helm , André Merbach

Magnetic Resonance in Chemistry, 1999, 37 (10), pp.701-708. ⟨10.1002/(SICI)1097-458X(199910)37:10<701::AID-MRC523>3.0.CO;2-6⟩

Article dans une revue istex hal-02080894v1

1H-NMRD and 17O-NMR assessment of water exchange and rotational dynamics of two potential MRI agents: MP-1177 (an extracellular agent) and MP-2269 (a blood pool agent).

M Adzamli , Éva Tóth , M Periasamy , S Koenig , M Merbach et al.

Magnetic Resonance Materials in Physics, Biology and Medicine, 1999, 8 (3), pp.163-71

Article dans une revue hal-02080889v1

Gadolinium-based linear polymer with temperature-independent proton relaxivities: a unique interplay between the water exchange and rotational contributions

Éva Tóth , Ingrid van Uffelen , Lothar Helm , André Merbach , David Ladd et al.

Magnetic Resonance in Chemistry, 1998, 36 (S1), pp.S125-S134. ⟨10.1002/(SICI)1097-458X(199806)36:1+3.0.CO;2-9⟩

Article dans une revue hal-02080930v1

Direct assessment of water exchange on a Gd(III) chelate bound to a protein

Éva Tóth , Fabienne Connac , Lothar Helm , Kofi Adzamli , André Merbach

Journal of Biological Inorganic Chemistry, 1998, 3 (6), pp.606-613. ⟨10.1007/s007750050273⟩

Article dans une revue istex hal-02080916v1

Water exchange dynamics: The key for high relaxivity contrast agents in medical resonance imaging

Éva Tóth , André E. Merbach

ACH-MODELS IN CHEMISTRY, 1998, 135 (5), pp.873-884

Article dans une revue hal-02266813v1

Structure and Dynamics of a Trinuclear Gadolinium(III) Complex: The Effect of Intramolecular Electron Spin Relaxation on Its Proton Relaxivity 1

Éva Tóth , Lothar Helm , André Merbach , Roman Hedinger , Kaspar Hegetschweiler et al.

Inorganic Chemistry, 1998, 37 (16), pp.4104-4113. ⟨10.1021/ic980146n⟩

Article dans une revue istex hal-02080926v1

17O-NMR, EPR and NMRD Characterization of [Gd(DTPA-BMEA)(H2O)]: A Neutral MRI Contrast Agent

Éva Tóth , Fabienne Connac , Lothar Helm , Kofi Adzamli , André Merbach

European Journal of Inorganic Chemistry, 1998, 1998 (12), pp.2017-2021. ⟨10.1002/(SICI)1099-0682(199812)1998:12<2017::AID-EJIC2017>3.0.CO;2-Z⟩

Article dans une revue istex hal-02080922v1

Trinuclear Lanthanoid Complexes of 1,3,5-Triamino-1,3,5-trideoxy-cis-inositol with a Unique, Sandwich-Type Cage Structure(1).

Roman Hedinger , Michele Ghisletta , Kaspar Hegetschweiler , Éva Tóth , André Merbach et al.

Inorganic Chemistry, 1998, 37 (26), pp.6698-6705

Article dans une revue hal-02080909v1

Tuning water-exchange rates on (carboxymethyl)iminobis(ethylenenitrilo)tetraacetate (dtpa)-type gadolinium(III) complexes

Éva Tóth , László Burai , Ernö Brücher , André Merbach

Journal of the Chemical Society Dalton Transactions, 1997, 9, pp.1587-1594. ⟨10.1039/A608505I⟩

Article dans une revue istex hal-02080942v1

Stability constants and1H relaxation effects of ternary complexes formed between gd-dtpa, gd-dtpa-bma, gd-dota, and gd-edta and citrate, phosphate, and carbonate ions

László Burai , Vesa Hietapelto , Róbert Király , Éva Tóth , Ernő Brücher

Magnetic Resonance in Medicine, 1997, 38 (1), pp.146-150. ⟨10.1002/mrm.1910380120⟩

Article dans une revue istex hal-02080946v1

Water Exchange and Rotational Dynamics of the Dimeric Gadolinium(III) Complex [BO{Gd(DO3A)(H 2 O)} 2 ]: A Variable-Temperature and -Pressure 17 O NMR Study 1

Éva Tóth , Sylvain Vauthey , Dirk Pubanz , André Merbach

Inorganic Chemistry, 1996, 35 (11), pp.3375-3379. ⟨10.1021/ic951492x⟩

Article dans une revue istex hal-02266810v1

The Role of Water Exchange in Attaining Maximum Relaxivities for Dendrimeric MRI Contrast Agents

Éva Tóth , Dirk Pubanz , Sylvain Vauthey , Lothar Helm , André Merbach

Chemistry - A European Journal, 1996, 2 (12), pp.1607-1615. ⟨10.1002/chem.19960021220⟩

Article dans une revue istex hal-02080951v1

Characterization of Lanthanide(III) DOTP Complexes: Thermodynamics, Protonation, and Coordination to Alkali Metal Ions

A. Sherry , J. Ren , J. Huskens , E. Brücher , Éva Tóth et al.

Inorganic Chemistry, 1996, 35 (16), pp.4604-4612. ⟨10.1021/ic9600590⟩

Article dans une revue istex hal-02080958v1

Equilibrium and kinetic studies on complexes of 10-[2,3-dihydroxy-(1-hydroxymethyl)-propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetate

Éva Tóth , R. Király , J. Platzek , B. Radüchel , E. Brücher

Inorganica Chimica Acta Reviews, 1996, 249 (2), pp.191-199. ⟨10.1016/0020-1693(96)05094-3⟩

Article dans une revue istex hal-02081004v1

Kinetics of Formation and Dissociation of Lanthanide(III)-DOTA Complexes

Éva Tóth , Erno Brucher , Istvan Lazar , Imre Toth

Inorganic Chemistry, 1994, 33 (18), pp.4070-4076. ⟨10.1021/ic00096a036⟩

Article dans une revue istex hal-02081012v1

Stability constants of the lanthanide(III)-1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-tetraacetate complexes

É. Tóth , E. Brücher

Inorganica Chimica Acta Reviews, 1994, 221 (1-2), pp.165-167. ⟨10.1016/0020-1693(94)03964-X⟩

Article dans une revue istex hal-02081015v1

Innovative nanobody-targeted nanoplatform delivering manganese contrast agents for MRI visualization of pancreatic islet beta cells

Marie Le Roy , Alexandre Barras , Daouda Ndiaye , Amar Abderrahmani , Eva Jakab-Toth et al.

Optimizing Imaging and Dose-Response in Radiotherapies Workshop, Canceropole Grand Ouest, Oct 2023, Erquy, France. 1 page

Communication dans un congrès hal-04182831v1

Metal complexes in imaging applications

Éva Tóth

Remise des prix de la SCF, Oct 2021, Clermont-Ferrand, France

Communication dans un congrès hal-03554946v1

Complexes de manganèse pour TEP et IRM : production du 52Mn et conception de ligands pour une complexation stable et inerte

Éva Tóth

Journée scientifique "Vectorisation, Imagerie, Radiothérapies" du Cancéropôle Grand Ouest, May 2021, webinar, France

Communication dans un congrès hal-03554938v1

Metal complexes for amyloid detection

Éva Tóth

54th Colloquium of Coordination Chemistry, May 2021, Budapest, Hungary

Communication dans un congrès hal-03554916v1

Direct Monitoring of Doxorubicin Release via sensitization of NIR-emitting Ytterbium Liposomes

S. Lacerda , Anthony Delalande , Svetlana V. Eliseeva , Agnes A. Pallier , Celia ́ Bonnet et al.

Journées du WP "Agents d'imagerie", WP1, de FLI et du GDR AIM, Nov 2021, Grenoble, France

Communication dans un congrès hal-03546197v1

Novel Bispidine-based Mn(II) complexes for PET/MR Imaging

S. Lacerda , Daouda Ndiaye , Isidro da Silva , Maryame Sy , Aline M. Nonat et al.

15th European Molecular Imaging Meeting, Aug 2020, Virtual, France

Communication dans un congrès hal-03549786v1

Responsive MRI Agents

Éva Tóth

Symposium “40 Years of MR Contrast Agents”, May 2019, Mons, Belgium

Communication dans un congrès hal-03283036v1

Enzymatic detection by MRI

Éva Tóth

The future of molecular MR - a Cellular and Molecular Imaging Workshop, Jul 2019, St. John's, Newfoundland, Canada

Communication dans un congrès hal-03283046v1

Séminaire invité : Molecular imaging agents based on lanthanide complexes

Éva Tóth

CEA - Service de Chimie Bioorganique et de Marquage, Mar 2019, Saclay, France

Communication dans un congrès hal-03282684v1

Séminaire invité : Molecular imaging agents based on lanthanide complexes

Éva Tóth

Institut Parisien de Chimie Moléculaire, Mar 2019, Paris, France

Communication dans un congrès hal-03282681v1

Séminaire invité : Molecular imaging agents based on lanthanide complexes

Éva Tóth

ENS, Feb 2019, Paris, France

Communication dans un congrès hal-03282678v1

Lanthanide complexes in molecular imaging

Éva Tóth

Conference at the Hungarian Academy of Sciences, Oct 2019, Budapest, Hungary

Communication dans un congrès hal-03283055v1

Complexes de lanthanide comme agents d'imagerie moléculaire

Éva Tóth

4e congrès de la Société Française de Résonance Magnétique en Biologie et Medicine, Mar 2019, Strasbourg, France

Communication dans un congrès hal-03283034v1

Medical imaging techniques: the role of chemistry

Éva Tóth

70 years of the Faculty of Sciences at the University of Debrecen, Nov 2019, Debrecen, Hungary

Communication dans un congrès hal-03283059v1

Metal-Based Responsive MR Probes

Éva Tóth

8th International Meeting of theInstitute of Metals in Biology of Grenoble, Sep 2019, Villard-de-Lans, France

Communication dans un congrès hal-03283052v1

Séminaire invité : Molecular imaging agents based on lanthanide complexes

Éva Tóth

Institut des Sciences du Vivant Frédéric Joliot, Apr 2018, Orsay, France

Communication dans un congrès hal-03282995v1

Responsive MRI probes based on lanthanides

Éva Tóth

Bracco Workshop “Advances in the Inorganic chemistry of MRI probes for contrast Enhancement”, Oct 2018, Milan, Italy

Communication dans un congrès hal-03283074v1

Lanthanide-Based Probes in Molecular Imaging

Éva Tóth

FrenchBIC 2018, Oct 2018, Carry-le-Rouet, France

Communication dans un congrès hal-03283153v1

MRI contrast agents and responsive probes

Éva Tóth

XXIIIrd International Krutyn Summer School “Advanced Lanthanide Molecules and Materials for Bioimaging and Medical Diagnostics: State of the Art”, May 2018, Krutyń, Masurian Lake District, Poland

Communication dans un congrès hal-03283062v1

Chemistry for Magnetic Resonance Imaging

Éva Tóth

French-Hungarian bilateral research conference, Sep 2018, Budapest, Hungary

Communication dans un congrès hal-03283068v1

Séminaire invité : Molecular imaging agents based on lanthanide complexes

Éva Tóth

University of Coimbra, Department of Life Sciences, Dec 2018, Coimbra, Portugal

Communication dans un congrès hal-03283012v1

Séminaire invité : Molecular imaging agents based on lanthanide complexes

Éva Tóth

Université autonome de Barcelone, Department of Chemistry, Feb 2018, Barcelone, Spain

Communication dans un congrès hal-03282992v1

Lanthanide-Based Responsive Probes for Magnetic Resonance Imaging - keynote lecture

Éva Tóth

10th International Conference on f-Elements, Sep 2018, Lausanne, Switzerland

Communication dans un congrès hal-03283064v1

Molecular Imaging Agents Based on Lanthanide Complexes

Éva Tóth

1st Meeting of the LIA “Mir-TANGo” bis, Jun 2017, Cracovie, Poland

Communication dans un congrès hal-03283216v1

Strategies to increase sensitivity of MRI contrast agents - Strategies to modulate efficiency: responsive probes

Éva Tóth

International Symposium “Molecular imaging agents in medicine”, Feb 2017, Groningen, Netherlands

Communication dans un congrès hal-03283123v1

Séminaire invité : Molecular imaging agents based on lanthanide complexes

Éva Tóth

Université de Manchester, School of Chemistry, Nov 2017, Manchester, United Kingdom

Communication dans un congrès hal-03283031v1

Agents de contraste intelligents pour la detection du zinc par IRM

P. Malikidogo K. , A. Pallier , J.-F. Morfin , Éva Tóth , S. Bonnet C.

Journées de Chimie de Coordination, Jan 2017, Grenoble, France

Communication dans un congrès hal-03283190v1

MRI in neuroscience

Éva Tóth

Molecular imaging and chemistry: defining the future, Mar 2017, Buckinghamshire, United Kingdom

Communication dans un congrès hal-03283125v1

Molecular Imaging Agents Based on Lanthanide Complexes

Éva Tóth

1st Meeting of the LIA “Mir-TANGo” bis, Jun 2017, Cracovie, Poland

Communication dans un congrès hal-03283176v1

Séminaire invité : Molecular imaging agents based on lanthanide complexes

Éva Tóth

Université de Rouen, May 2017, Rouen, France

Communication dans un congrès hal-03283018v1

Séminaire invité : Molecular imaging agents based on lanthanide complexes

Éva Tóth

Université d’Uppsala, Department of Chemistry, Oct 2017, Uppsala, Sweden

Communication dans un congrès hal-03283021v1

Molecular imaging agents based on lanthanide complexes - keynote lecture

Éva Tóth

16th European Biological Inorganic Chemistry Conference – EuroBIC-16, Aug 2016, Budapest, Hungary

Communication dans un congrès hal-03283134v1

Molecular Imaging Agents Based on Lanthanide Complexes

Éva Tóth

3rd Meeting of the LIA “Mir-TANGo”, May 2016, Orléans, France

Communication dans un congrès hal-03283182v1

Molecular imaging agents based on lanthanide complexes – invited plenary lecture

Éva Tóth

RICT 2016 Interfacing Chemical Biology and Drug Discovery, Jul 2016, Caen, France

Communication dans un congrès hal-03283131v1

Responsive and Multimodal Imaging Probes Based on Lanthanide Complexes

Éva Tóth

3rd European Colloquium on Inorganic Reaction Mechanisms, Jun 2016, Cracovie, Poland

Communication dans un congrès hal-03283183v1

Lanthanide Containing Nanoparticles in Theranostic Approaches

Éva Tóth

Le Studium conference “Medicinal flavor of metal complexes: diagnostic and therapeutic applications”, Sep 2016, Orléans, France

Communication dans un congrès hal-03283188v1

Apport de la chimie pour les agents de contraste IRM pour l’imagerie de l’infection bactérienne

Éva Tóth

Atelier FLI/IDMIT « Imagerie de l’infection et de l’inflammation », May 2016, Paris, France

Communication dans un congrès hal-03283220v1

Lanthanide-based molecular imaging agents

Éva Tóth

French-Czech Vltava Chemistry Meeting, Sep 2016, Orléans, France

Communication dans un congrès hal-03283136v1

Lanthanide Containing Nanoparticles in Theranostic Approaches

Éva Tóth

42nd International Conference on Coordination Chemistry, Jul 2016, Brest, France

Communication dans un congrès hal-03283185v1

SPECT / MRI quantitative detection of zinc using a cocktail of 165Er(III) and Gd(III) complexes

Kyangwi Malikidogo , I. da Silva , Jean-François Morfin , S. Lacerda , Laurent Barantin et al.

14th European Molecular Imaging Meeting, Mar 2019, Glasgow, United Kingdom

Poster de conférence hal-03292258v1

MRI contrast agents for quantitative zinc detection

P. Malikidogo K. , Jean-François Morfin , S. Lacerda , I. da Silva , Laurent Barantin et al.

GDR Agents d’Imagerie Moléculaire (AIM), Jun 2018, Orléans, France

Poster de conférence hal-03296044v1

GRPr-Targeted Gold Nanoparticles for Multimodal Imaging

S. Lacerda , F. Silva , L. Gano , Agnes A. Pallier , Sandra Même et al.

13th European Molecular Imaging Meeting, Mar 2018, San Sebastien, Spain

Poster de conférence hal-03294463v1

X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations

S. Lacerda , Slávka Kaščáková , Agnès Pallier , Alexandre Giuliani , Pascal Mercère et al.

12th annual meeting of the European Society for Molecular Imaging – ESMI, Apr 2017, Cologne, Germany

Poster de conférence hal-02453469v1

Gold Nanoprobe for Translational Multimodal imaging

C. Campello M. P. , F. Silva , A. Paulo , L. Gano , R. Kannan et al.

Le Studium conference “Is Multimodal Imaging an invention with a future? The input of chemistry”, Dec 2017, Orléans, France

Poster de conférence hal-03300611v1

X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations

Slávka Kaščáková , S. Lacerda , Agnès Pallier , Alexandre Giuliani , Pascal Mercère et al.

SFNano Annual Meeting 2016, Dec 2016, Paris, France

Poster de conférence hal-02453468v1

X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations

S. Kaščáková , S. Lacerda , Agnes A. Pallier , A. Giuliani , P. Mercère et al.

6th EuCheMS Chemistry Congress, Sep 2016, Seville, Spain

Poster de conférence hal-03300671v1

Zinc responsive contrast agents

Kyangwi Malikidogo , Agnes A. Pallier , Jean-François Morfin , Éva Tóth , Celia ́ Bonnet

International Conference on Coordination Chemistry (ICCC), Jul 2016, Brest, France

Poster de conférence hal-03300659v1

Smart MRI contrast agents for zinc detection

Kyangwi Malikidogo , Agnes A. Pallier , Jean-François Morfin , Éva Tóth , Celia ́ Bonnet

Le Studium conférence “Being smart in coordination chemistry: Medical Applications”, Sep 2016, Orléans, France

Poster de conférence hal-03300683v1

Smart MRI contrast agents for zinc detection

Kyangwi Malikidogo , Agnes A. Pallier , Jean-François Morfin , Éva Tóth , Celia ́ Bonnet

Colloque association des doctorants du CBM, Feb 2016, Orléans, France

Poster de conférence hal-03300628v1

Mn-Based Small Complexes as MRI Contrast Agents

Zoltán Garda , Sara Lacerda , Éva Tóth

Lanthanide and Other Transition Metal Ion Complexes and Nanoparticles in Magnetic Resonance Imaging, 1, CRC Press, pp.151-180, 2024, ⟨10.1201/9781003374688-5⟩

Chapitre d'ouvrage hal-04780845v1

MRI relaxation agents based on transition metals

Sara Lacerda , Daouda Ndiaye , Éva Tóth

Colin D. Hubbard; Rudi van Eldik. Advances in Inorganic Chemistry: Recent Highlights I, 78, Elsevier, pp.109-142, 2021, Advances in Inorganic Chemistry, 978-0-323-85115-2. ⟨10.1016/bs.adioch.2021.06.001⟩

Chapitre d'ouvrage hal-03812422v1

Transition metal-based MRI relaxation agents (Mn and Fe)

S. Lacerda , Daouda Ndiaye , Éva Tóth

Advances in Inorganic Chemistry: Recent Highlights, 78, 2021, 9780323851152

Chapitre d'ouvrage hal-03549862v1

Des agents intelligents pour l'imagerie

Bich Thuy Doan , Éva Tóth

Pradier C.-M., Parisel O., Teyssandier F. Etonnante chimie : Découvertes et promesses du XXIème siècle, CNRS Editions, pp.230-235, 2021, 9782271136527

Chapitre d'ouvrage hal-03638357v1

Manganese Complexes as Contrast Agents for Magnetic Resonance Imaging

S. Lacerda , Daouda Ndiaye , Éva Tóth

Astrid Sigel Eva Freisinger and Roland K.O. Sigel. Metal Ions in Bio-Imaging Techniques, De Gruyter, pp.71-100, 2021, 9783110685565. ⟨10.1515/9783110685701-009⟩

Chapitre d'ouvrage hal-03549867v1

Dual Imaging Gold Nanoplatforms for Targeted Radiotheranostics

S. Lacerda , Francisco J. Silva , Paulo Antonio , Agnes A. Pallier , Sandra Même et al.

Prime Archives in Material Science, 2020, 978-93-90014-26-2

Chapitre d'ouvrage hal-03549858v1

Molecular Probes for Magnetic Resonance Imaging of Amyloid β Peptides

Carlos F.G.C. Geraldes , Sara Lacerda , Éva Tóth

Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, 2018, 9780124095472. ⟨10.1016/B978-0-12-409547-2.13926-5⟩

Chapitre d'ouvrage hal-02080790v1

Molecular Magnetic Resonance Imaging Probes Based on Ln3+ Complexes

Célia Bonnet , Éva Tóth

Advances in Inorganic Chemistry, pp.43-96, 2016, ⟨10.1016/bs.adioch.2015.09.002⟩

Chapitre d'ouvrage hal-02081246v1

Metal Complexes as MRI Contrast Enhancement Agents

É. Tóth , L. Helm , A.E. Merbach

Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, 2015, 978-0-12-409547-2. ⟨10.1016/B978-0-12-409547-2.11263-6⟩

Chapitre d'ouvrage hal-02081242v1

MRI Contrast Agents

Célia Bonnet , Éva Tóth

Ligand Design in Medicinal Inorganic Chemistry, John Wiley & Sons, Ltd, pp.321-354, 2014, ⟨10.1002/9781118697191.ch12⟩

Chapitre d'ouvrage hal-02081236v1

Relaxivity of Gadolinium(III) Complexes: Theory and Mechanism

Éva Tóth , Lothar Helm , André Merbach

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging, Second Edition, John Wiley & Sons, Ltd, pp.25-81, 2013, ⟨10.1002/9781118503652.ch2⟩

Chapitre d'ouvrage hal-02070939v1

Responsive Probes

Celia S. Bonnet , Lorenzo Tei , Mauro Botta , Éva Tóth

Merbach Andre S., Helm Lothar, Tóth Eva. The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging, John Wiley & Sons, pp.343-385, 2013, 978-1-119-99176-2

Chapitre d'ouvrage hal-00876916v1

MRI Contrast Agents, In Supramolecular Chemistry : From Molecules to Nanomaterials

Eva Jakab-Toth , Célia Bonnet

Jonathan W. Steed, Philip A. Gale. Self-Assembly and Supramolecular Devices, 5, John Wiley & Sons, Ltd, pp.2693-2723, 2012, 978-0-470-74640-0. ⟨10.1002/9780470661345.Smc104⟩

Chapitre d'ouvrage hal-02071809v1

Gadolinium-Based Bionanomaterials for Magnetic Resonance Imaging

Lothar Helm , Éva Tóth

BALAJI SITHARAMAN. Nanobiomaterials Handbook, CRC Press, pp.1-34, 2011, ⟨10.1201/b10970-19⟩

Chapitre d'ouvrage hal-00614947v1

Metal Complexes as MRI Contrast Enhancement Agents

Éva Tóth , L. Helm , André E. Merbach

Jon A. Mc Cleverty, J. Thomas. Compréhensive Coordination Chemistry II, 9, Elsevier, pp.841-881, 2004

Chapitre d'ouvrage hal-02266849v1

Lanthanide ions as magnetic resonance imaging agents. Nuclear and electronic relaxation properties. Applications.

Lothar Helm , Éva Tóth , André Merbach

Metal Ionsin Biological Systems, 40 (15), Marcel Dekker INC., pp.589-642, 2003

Chapitre d'ouvrage hal-02266852v1

Relaxivity of MRI Contrast Agents

Éva Tóth , Lothar Helm , André Merbach

Topics in Current Chemistry, 221 (2), pp.61-101, 2002, 978-3-540-42247-1

Chapitre d'ouvrage hal-02266848v1