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Eva Jakab Toth

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JAKAB TÓTH Éva ============== Directrice de recherche 1ère classe CNRS Adresse professionnnelle : Centre de Biophysique Moléculaire, CNRS, Rue Charles Sadron, 45071 Orléans, Cedex 2, France Phone: +33 2 38 25 55 89 E-mail : eva.jakabtoth@cnrs-orleans.fr http://cbm.cnrs-orleans.fr/ FORMATION - TITRES SCIENTIFIQUES -------------------------------- 1990 Diplôme universitaire en chimie "Summa cum laude" (Université de Debrecen, Hongrie) 1994 Doctorat en chimie de l'Université de Debrecen, Hongrie (avec félicitations du jury ; summa cum laude) 2004 Habilitation auprès de l'Académie des Sciences de Hongrie 2007 Qualification "Professeurs des Universités" - Section 32 EXPÉRIENCES PROFESSIONNELLES ---------------------------- 1995-2000 Stage post-doctoral et première assistante à l'Université de Lausanne, Suisse 2001 Maître assistante à l'Université de Lausanne 2001-2005 Chargée de cours à l'École Polytechnique Fédérale de Lausanne, Suisse 2005 Directrice de Recherche CNRS (DR2) au Centre de Biophysique Moléculaire - CNRS, Orléans, France 2013 Promotion DR1 2012 - Directrice du Centre de Biophysique Moléculaire (140 personnes) DISTINCTIONS ------------ 1990 Prix de la Faculté des Sciences, Université de Debrecen, Hongrie 2018 Médaille d'argent du CNRS ACTIVITÉS DE RECHERCHE ---------------------- Conception, synthèse et caractérisation de nouvelles sondes à base de complexes de lanthanides pour l'imagerie biomédicale Auteur de 162 publications dans des journaux internationaux, 14 chapitres de livre, 3 brevets. Co-editeur du livre "The Chemistry of Contrats Agents in Medical Magnetic Resonance Imaging" (Wiley & sons 2001 (1st edition), 2013 (2nd edition). h-factor: 50. 78 invited conferences and seminars. ACTIVITÉS DE FORMATION ---------------------- Direction de 14 thèses, 6 post-docs Accueil de 28 étudiants et post-doctorants en échange ; 6 professeurs invités Enseignement au Master International "Bioimaging" Paris Descartes (2011- ) RESPONSABILITÉS SCIENTIFIQUES - ACTIVITÉS DE MANAGEMENT ------------------------------------------------------- - Chair du réseau européen COST D38 "Metal-based systems for molecular imaging applications" (2008-2012 ; 50 laboratoires participants) ; Grant holder de l'Action COST TD1004 "Theranostics " (2012-2015) - Directrice du Groupement de Recherche (GDR) "Agents d'Imagerie Moléculaire" , France (~ 40 laboratoires partenaires) - Directrice du laboratoire International Associé "MirTANGO bis" avec l'Université Jaggelon de Cracovie, Pologne (2016-2020) - Membre de "Scientific Advisory Board" de Max Planck Institute for Biological Cybernetics, Tübingen, Germany (2008-2016) - Membre de "Scientific Advisory Board" of Maloposka Institute of biotechnology, Cracovie, Pologne (2016 - ) - Membre du conseil Scientifique de l'Institut Multidisciplinaire Hubert Curien, Strasbourg (2011-) - Co-coordinator of the working Group "Chemistry for probes and contrast" in France Life Imaging - Membre de "International Advisory Board of Inorganic Chemistry" (ACS ; 2015-2017) - Membre de "International Advisory board of ChemMedChem" (Wiley ; 2017 - ) ORGANISATION DE CONFÉRENCES --------------------------- - Final COST D18 meeting "Lanthanide Chemistry for Diagnosis and Therapy", 31 march - 1 April 2006, Orléans, France - 1st Working Group Meeting "MRI Contrast Agents" du COST D38, Orléans, 8-9 Dec. 2006 ; 2nd Working Group Meeting "MRI Contrast Agents" du COST D38, Orléans, 29 Febr. - 1 March 2008 ; 3ème journées du groupe Polyamines, 14-16 June 2011, Orléans - 2010-2012: Member of the Scientific Organizing Committee of the european Molecular Imaging Meeting (EMIM), responsable for "Imaging Probe Design" sessions - Member of the Scientific Organizing Committee for Dalton discussions: Metal ions in Medical Imaging, York, Sept. 2014 - Member of the National Organizing Committee for ICC42 in Brest, France, 2016 - Convenor for the session "Methods and Application at the chemistry-Biology interface" at EuChems 2016, Sevilla - Medical Flavour of Metal Complexes, Studium Conference, Orléans, 8-10 Dec. 2015 - Being Smart in Coordination Chemistry, Studium conference, Orléans, 26-28 Sept. 2016 - Is Multimodal Imaging an Invention with future ? The input of chemistry, Studium conference, Orléans, 11-12 Dec. 2017 - Journées scientifiques du GDR AIM, juin 2018, Orléans

Publications

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A New Oxygen Containing Pyclen-Type Ligand as a Manganese(II) Binder for MRI and 52Mn PET Applications: Equilibrium, Kinetic, Relaxometric, Structural and Radiochemical Studies

Tibor Csupász , Dániel Szücs , Ferenc Krisztián Kálmán , Oldamur Hollóczki , Anikó Fekete et al.
Molecules, 2022, 27 (2), pp.371. ⟨10.3390/molecules27020371⟩
Journal articles hal-03842397v1

55/52 Mn 2+ Complexes with a Bispidine-Phosphonate Ligand: High Kinetic Inertness for Imaging Applications

Maryame Sy , Daouda Ndiaye , Isidro da Silva , Sara Lacerda , Loïc Charbonnière et al.
Inorganic Chemistry, 2022, 61 (34), pp.13421-13432. ⟨10.1021/acs.inorgchem.2c01681⟩
Journal articles hal-03842435v1
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Gd III and Ga III complexes with a new tris-3,4-HOPO ligand as new imaging probes: complex stability, magnetic properties and biodistribution

Silvia Chaves , Karolina Gwizdała , Karam Chand , Lurdes Gano , Agnes A. Pallier et al.
Dalton Transactions, 2022, 51 (16), pp.6436-6447. ⟨10.1039/D2DT00066K⟩
Journal articles hal-03842391v1
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Rigidified Derivative of the Non-macrocyclic Ligand H 4 OCTAPA for Stable Lanthanide(III) Complexation

Fátima Lucio-Martínez , Zoltán Garda , Balázs Váradi , Ferenc Krisztián Kálmán , David Esteban-Gómez et al.
Inorganic Chemistry, 2022, 61 (12), pp.5157-5171. ⟨10.1021/acs.inorgchem.2c00501⟩
Journal articles hal-03842348v1

Metal complexes for the visualisation of amyloid peptides

Jean-François Morfin , Sara Lacerda , Carlos Geraldes , Éva Tóth
Sensors & Diagnostics, 2022, 1 (4), pp.627-647. ⟨10.1039/D2SD00026A⟩
Journal articles hal-03842376v1

On the Versatility of Nanozeolite Linde Type L for Biomedical Applications: Zirconium-89 Radiolabeling and In Vivo Positron Emission Tomography Study

Sara Lacerda , Wuyuan Zhang , Rafael T. M. de Rosales , Isidro da Silva , Julien Sobilo et al.
ACS Applied Materials & Interfaces, 2022, 14 (29), pp.32788-32798. ⟨10.1021/acsami.2c03841⟩
Journal articles hal-03842373v1
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Exceptional Manganese(II) Stability and Manganese(II)/Zinc(II) Selectivity with Rigid Polydentate Ligands**

Patrick Cieslik , Peter Comba , Benedikt Dittmar , Daouda Ndiaye , Éva Tóth et al.
Angewandte Chemie International Edition, 2022, 61 (10), ⟨10.1002/anie.202115580⟩
Journal articles hal-03842387v1
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Gd3+ Complexes Conjugated to Cyclodextrins: Hydroxyl Functions Influence the Relaxation Properties

Anais Biscotti , François Estour , Berthe-Sandra Sembo-Backonly , Sebastien Balieu , Michaël Bosco et al.
Processes, 2021, 9 (2), pp.269. ⟨10.3390/pr9020269⟩
Journal articles hal-03127005v1
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Stability, relaxometric and computational studies on Mn 2+ complexes with ligands containing a cyclobutane scaffold

Oriol Porcar-Tost , Agnès Pallier , David Esteban-Gómez , Ona Illa , Carlos Platas-Iglesias et al.
Dalton Transactions, 2021, 50 (3), pp.1076-1085. ⟨10.1039/D0DT03402A⟩
Journal articles hal-03442176v1
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Doxorubicin‐sensitized Luminescence of NIR‐emitting Ytterbium Liposomes: Towards Direct Monitoring of Drug Release

S. Lacerda , Anthony Delalande , Svetlana V. Eliseeva , Agnes A. Pallier , Celia ́ Bonnet et al.
Angewandte Chemie International Edition, 2021, 60 (44), pp.23574-23577. ⟨10.1002/anie.202109408⟩
Journal articles hal-03349106v1
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Complexation of Mn(II) by Rigid Pyclen Diacetates: Equilibrium, Kinetic, Relaxometric, Density Functional Theory, and Superoxide Dismutase Activity Studies

Zoltán Garda , Enikő Molnár , Nadège Hamon , José Luis Barriada , David Esteban-Gómez et al.
Inorganic Chemistry, 2021, ⟨10.1021/acs.inorgchem.0c03276⟩
Journal articles hal-03094039v1
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Expanding the Ligand Classes Used for Mn(II) Complexation: Oxa-aza Macrocycles Make the Difference

Ferenc K Kálmán , Viktória Nagy , Rocío Uzal-Varela , Paulo Pérez-Lourido , David Esteban-Gómez et al.
Molecules, 2021, 26 (6), pp.1524. ⟨10.3390/molecules26061524⟩
Journal articles hal-03442182v1
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Concentration‐dependent interactions of amphiphilic PiB‐ derivative metal complexes with amyloid peptides Aβ and amylin

Saida Majdoub , Zoltán Garda , Alexandre Oliveira , Inga Relich , Agnes A. Pallier et al.
Chemistry - A European Journal, 2021, 27, pp.2009-2020. ⟨10.1002/chem.202004000⟩
Journal articles hal-03011656v1
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Comparison of the equilibrium, kinetic and water exchange properties of some metal ion-DOTA and DOTA-bis(amide) complexes

Gyula Tircsó , Enikő Tircsóné Benyó , Zoltán Garda , Jaspal Singh , Robert Trokowski et al.
Journal of Inorganic Biochemistry, 2020, 206, pp.111042. ⟨10.1016/j.jinorgbio.2020.111042⟩
Journal articles hal-03011487v1
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Photophysical studies on lanthanide( iii ) chelates conjugated to Pittsburgh compound B as luminescent probes targeted to Aβ amyloid aggregates

Alexandre Oliveira , Telma Costa , Licinia Justino , Rui Fausto , Jean-François Morfin et al.
Photochemical & Photobiological Sciences , 2020, 19 (11), pp.1522-1537. ⟨10.1039/D0PP00214C⟩
Journal articles hal-03011501v1
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Unexpected Trends in the Stability and Dissociation Kinetics of Lanthanide(III) Complexes with Cyclen-Based Ligands across the Lanthanide Series

Zoltán Garda , Viktória Nagy , Aurora Rodríguez-Rodríguez , Rosa Pujales-Paradela , Véronique Patinec et al.
Inorganic Chemistry, 2020, 59 (12), pp.8184-8195. ⟨10.1021/acs.inorgchem.0c00520⟩
Journal articles hal-02564517v1
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Dual Imaging Gold Nanoplatforms for Targeted Radiotheranostics

Francisco Silva , António Paulo , Agnès Pallier , S. Même , Éva Tóth et al.
Materials, 2020, 13 (3), pp.513. ⟨10.3390/ma13030513⟩
Journal articles hal-02472491v1
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LDL-mimetic lipid nanoparticles prepared by surface KAT ligation for in vivo MRI of atherosclerosis

Alessandro Fracassi , Jianbo Cao , Naoko Yoshizawa-Sugata , Éva Tóth , Corey Archer et al.
Chemical Science, 2020, ⟨10.1039/d0sc04106h⟩
Journal articles hal-03011633v1
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Synthesis and In Vitro Studies of a Gd(DOTA)–Porphyrin Conjugate for Combined MRI and Photodynamic Treatment

Sébastien Jenni , Celia ́ Bonnet , Frédéric Bolze , Agnes A. Pallier , Angélique Sour et al.
Inorganic Chemistry, 2020, 59 (19), pp.14389-14398. ⟨10.1021/acs.inorgchem.0c02189⟩
Journal articles hal-03011644v1
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Mn(II)-based MRI contrast agent candidate for vascular imaging

Ferenc K Kalman , Viktória Nagy , Balázs Váradi , Zoltán Garda , Enikő Molnár et al.
Journal of Medicinal Chemistry, 2020, 63 (11), pp.6057-6065. ⟨10.1021/acs.jmedchem.0c00197⟩
Journal articles hal-02996069v1
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Unprecedented kinetic inertness for a Mn2+‐bispidine chelate: a novel structural entry for Mn2+‐based imaging agents

Daouda Ndiaye , Maryame Sy , Agnès Pallier , Sandra Même , Isidro de Silva et al.
Angewandte Chemie International Edition, 2020, 59 (29), pp.11958-11963. ⟨10.1002/anie.202003685⟩
Journal articles hal-02555574v1
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Des agents intelligents pour l’imagerie moléculaire

Éva Tóth
L'Actualité Chimique, 2019, 446, pp.11-17
Journal articles hal-03036754v1
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Toward MRI and Optical Detection of Zwitterionic Neurotransmitters: Near-Infrared Luminescent and Magnetic Properties of Macrocyclic Lanthanide(III) Complexes Appended with a Crown Ether and a Benzophenone Chromophore

Fatima Oukhatar , Svetlana Eliseeva , Celia ́ Bonnet , Matteo Placidi , Nikos Logothetis et al.
Inorganic Chemistry, 2019, 58 (20), pp.13619-13630. ⟨10.1021/acs.inorgchem.9b00887⟩
Journal articles hal-02355920v1
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High‐Field Detection of biomarkers with Fast Field‐Cycling MRI: The Example of Zinc Sensing

Markus Bödenler , Kyangwi Malikidogo , Jean-François Morfin , Christoph Aigner , Éva Tóth et al.
Chemistry - A European Journal, 2019, ⟨10.1002/chem.201901157⟩
Journal articles hal-02117697v1
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A biocompatible redox MRI probe based on a Mn( ii )/Mn( iii ) porphyrin

Sara Pinto , Mário Calvete , Mariana Ghica , Sérgio Soler , Iluminada Gallardo et al.
Dalton Transactions, 2019, 48 (10), pp.3249-3262. ⟨10.1039/c8dt04775h⟩
Journal articles hal-02071232v1
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Responsive ParaCEST Contrast Agents

Éva Tóth , Celia ́ Bonnet
Inorganics, 2019, 7 (5), pp.68. ⟨10.3390/inorganics7050068⟩
Journal articles hal-02355925v1
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Gadolinium Complexes of Highly Rigid, Open-Chain Ligands Containing a Cyclobutane Ring in the Backbone: Decreasing Ligand Denticity Might Enhance Kinetic Inertness

Oriol Porcar-Tost , Jose Olivares , Agnès Pallier , David Esteban-Gómez , Ona Illa et al.
Inorganic Chemistry, 2019, 58 (19), pp.13170-13183. ⟨10.1021/acs.inorgchem.9b02044⟩
Journal articles hal-02358960v1
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Metal-based redox-responsive MRI contrast agents

Sara Pinto , Vanessa Tomé , Mário J.F. Calvete , M. Margarida C.A. Castro , Éva Tóth et al.
Coordination Chemistry Reviews, 2019, 390, pp.1-31. ⟨10.1016/j.ccr.2019.03.014⟩
Journal articles hal-02358923v1

Mn 2+ complexes of open-chain ligands with a pyridine backbone: less donor atoms lead to higher kinetic inertness

Sophie Laine , Célia Bonnet , Ferenc Kálmán , Zoltán Garda , Agnès Pallier et al.
New Journal of Chemistry, 2018, 42 (10), pp.8012-8020. ⟨10.1039/C8NJ00648B⟩
Journal articles hal-01966154v1

Functionalised Carbon Nanotubes Enhance Brain Delivery of Amyloid-Targeting Pittsburgh Compound B (PiB)-Derived Ligands

Pedro Miguel Costa , Julie Tzu-Wen Wang , Jean-François Morfin , Tamanna Khanum , Wan To et al.
Nanotheranostics, 2018, 2 (2), pp.168-183. ⟨10.7150/ntno.23125⟩
Journal articles hal-02080078v1
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A cocktail of 165 Er( iii ) and Gd( iii ) complexes for quantitative detection of zinc using SPECT and MRI

Kyangwi Malikidogo , Isidro da Silva , Jean-François Morfin , Sara Lacerda , Laurent Barantin et al.
Chemical Communications, 2018, 54 (55), pp.7597 - 7600. ⟨10.1039/c8cc03407a⟩
Journal articles hal-01904447v1

A Bishydrated, Eight-Coordinate Gd(III) Complex with Very Fast Water Exchange: Synthesis, Characterization, and Phantom MR Imaging

Bedika Phukan , Kyangwi Malikidogo , Célia Bonnet , Éva Tóth , Samsuzzoha Mondal et al.
ChemistrySelect, 2018, 3 (27), pp.7668-7673. ⟨10.1002/slct.201801629⟩
Journal articles hal-02071241v1
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A Porphyrin Dimer–GdDOTA Conjugate as a Theranostic Agent for One- and Two-Photon Photodynamic Therapy and MRI

Julie Schmitt , Sébastien Jenni , Angélique Sour , Valérie Heitz , Frédéric Bolze et al.
Bioconjugate Chemistry, 2018, 29 (11), pp.3726-3738. ⟨10.1021/acs.bioconjchem.8b00634⟩
Journal articles hal-02071234v1
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Luminescence Properties of Self-Aggregating TbIII-DOTA-Functionalized Calix[4]arenes

Florian Mayer , Sriram Tiruvadi Krishnan , Daniel Schühle , Svetlana Eliseeva , Stéphane Petoud et al.
Frontiers in Chemistry, 2018, 6, pp.1. ⟨10.3389/fchem.2018.00001⟩
Journal articles hal-02519038v1
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Remarkable differences and similarities between the isomeric Mn(II)- cis - and trans- 1,2-diaminocyclohexane- N , N , N ′, N ′-tetraacetate complexes

Enikő Molnár , Balázs Váradi , Zoltán Garda , Richárd Botár , Ferenc Kálmán et al.
Inorganica Chimica Acta, 2018, 472, pp.254-263
Journal articles hal-02572224v1
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Theranostics and Image Guided Drug Delivery. Edited by Maya Thanou

Sara Lacerda , Éva Tóth
ChemMedChem, 2018, 13 (17), pp.1851-1852. ⟨10.1002/cmdc.201800464⟩
Journal articles hal-01966410v1
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Proton-exchange in a paramagnetic chemical exchange saturation transfer agent from experimental studies and ab initio metadynamics simulation

Rodolphe Pollet , Celia ́ Bonnet , Pascal ́ Retailleau , Philippe ́ Durand , Éva Tóth et al.
Inorganic Chemistry, 2017, 56, pp.4317-4323. ⟨10.1021/acs.inorgchem.6b02773⟩
Journal articles cea-01496904v1

Strategies for sensing neurotransmitters with responsive MRI contrast agents

Goran Angelovski , Éva Tóth
Chemical Society Reviews, 2017, 46 (2), pp.324 - 336. ⟨10.1039/C6CS00154H⟩
Journal articles hal-01632884v1
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Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting.

Jonathan Pansieri , Marie Plissonneau , Nathalie Stransky-Heilkron , Mireille Dumoulin , Laurence Heinrich-Balard et al.
Nanomedicine, 2017, 12 (14), pp.1675-1687. ⟨10.2217/nnm-2017-0079⟩
Journal articles hal-01561318v1

Surface PEG Grafting Density Determines Magnetic Relaxation Properties of Gd-Loaded Porous Nanoparticles for MR Imaging Applications

Wuyuan Zhang , Jonathan Martinelli , Joop A. Peters , Jacob M.A. van Hengst , Hans Bouwmeester et al.
ACS Applied Materials & Interfaces, 2017, 9 (28), pp.23458 - 23465. ⟨10.1021/acsami.7b05912⟩
Journal articles hal-01632905v1
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Metal complexes for multimodal imaging of misfolded protein-related diseases

S. Lacerda , J.-F. Morfin , C. F G C Geraldes , É. Tóth
Dalton Transactions, 2017, 46 (42), pp.14461-14474. ⟨10.1039/C7DT02371E⟩
Journal articles hal-02068723v1
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Mechanostereoselective One-Pot Synthesis of Functionalized Head-to-Head Cyclodextrin [3]Rotaxanes and Their Application as Magnetic Resonance Imaging Contrast Agents

Jean Wilfried Fredy , Jérémy Scelle , Gregory Ramniceanu , Bich-Thuy Doan , Célia S. Bonnet et al.
Organic Letters, 2017, 19 (5), pp.1136-1139. ⟨10.1021/acs.orglett.7b00153⟩
Journal articles hal-01480341v1

Next-Generation Magnetic Resonance Imaging Contrast Agents

Janet Morrow , Éva Tóth
Inorganic Chemistry, 2017, 56 (11), pp.6029-6034. ⟨10.1021/acs.inorgchem.7b01277⟩
Journal articles hal-02071700v1

Lanthanide Complexes in Molecular Magnetic Resonance Imaging and Theranostics

Sara Lacerda , Éva Tóth
ChemMedChem, 2017, 12 (12), pp.883 - 894. ⟨10.1002/cmdc.201700210⟩
Journal articles hal-01618333v1
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Novel CDTA-based, Bifunctional Chelators for Stable and Inert Mn II Complexation: Synthesis and Physicochemical Characterization

Christian Vanasschen , Enikő Molnár , Gyula Tircso , Ferenc Kálmán , Éva Tóth et al.
Inorganic Chemistry, 2017, 56 (14), pp.7746 - 7760. ⟨10.1021/acs.inorgchem.7b00460⟩
Journal articles hal-02572209v1
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A Theranostic Agent Combining a Two-Photon-Absorbing Photosensitizer for Photodynamic Therapy and a Gadolinium(III) Complex for MRI Detection

Julie Schmitt , Valérie Heitz , Angélique Sour , Frédéric Bolze , Pascal Kessler et al.
Chemistry - A European Journal, 2016, 22 (8), pp.2775-2786. ⟨10.1002/chem.201503433⟩
Journal articles hal-01407691v1

The quest for biocompatible phthalocyanines for molecular imaging: Photophysics, relaxometry and cytotoxicity studies

Sara M.A. Pinto , Vanessa A. Tomé , Mário J.F. Calvete , Mariette M. Pereira , Hugh D. Burrows et al.
Journal of Inorganic Biochemistry, 2016, 154, pp.50 - 59. ⟨10.1016/j.jinorgbio.2015.10.013⟩
Journal articles hal-01407515v1

Gallium-68 Complexes Conjugated to Pittsburgh Compound B: Radiolabeling and Biological Evaluation

D Cressier , M Dhilly , Tt Cao Pham , F Fillesoye , F Gourand et al.
Molecular Imaging and Biology, 2016, 18 (3), pp.334-43. ⟨10.1007/s11307-015-0906-9⟩
Journal articles hal-01575680v1

pH-responsive relaxometric behaviour of coordination polymer nanoparticles made of a stable macrocyclic gadolinium macrocyclic chelate

J. Aríñez-Soriano , Albalad J. , Carné-Sánchez J. , Celia ́ Bonnet , Busqué C. S. et al.
Chemistry - A European Journal, 2016, 22 (37), pp.13162-13170. ⟨10.1002/chem.201602356⟩
Journal articles hal-01405351v1

Approaching the Kinetic Inertness of Macrocyclic Gadolinium(III)-Based MRI Contrast Agents with Highly Rigid Open-Chain Derivatives

Gyula Tircsó , Martín Regueiro-Figueroa , Viktória Nagy , Zoltán Garda , Tamás Garai et al.
Chemistry - A European Journal, 2016, 22 (3), pp.896 - 901. ⟨10.1002/chem.201503836⟩
Journal articles hal-01407817v1
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Prototypes of Lanthanide(III) Agents Responsive to Enzymatic Activities in Three Complementary Imaging Modalities: Visible/Near-Infrared Luminescence, PARACEST-, and T 1 -MRI

Jiefang He , Célia S. Bonnet , Svetlana V. Eliseeva , Sara Lacerda , Thomas Chauvin et al.
Journal of the American Chemical Society, 2016, 138 (9), pp.2913 - 2916. ⟨10.1021/jacs.5b12084⟩
Journal articles hal-01407004v1
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Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting.

Marie Plissonneau , Jonathan Pansieri , Laurence Heinrich-Balard , Jean-François Morfin , Nathalie Stransky-Heilkron et al.
Journal of Nanobiotechnology, 2016, 14 (1), pp.60. ⟨10.1186/s12951-016-0212-y⟩
Journal articles hal-01356748v1

Smart Contrast Agents for Magnetic Resonance Imaging

Célia S. Bonnet , Éva Tóth
CHIMIA, 2016, 70 (1), pp.102 - 108. ⟨10.2533/chimia.2016.102⟩
Journal articles hal-01405839v1

Four Gadolinium(III) Complexes Appended to a Porphyrin: A Water-Soluble Molecular Theranostic Agent with Remarkable Relaxivity Suited for MRI Tracking of the Photosensitizer

Angélique Sour , Sébastien Jenni , Ana Ortí-Suárez , Julie Schmitt , Valérie Heitz et al.
Inorganic Chemistry, 2016, 55 (9), pp.4545 - 4554. ⟨10.1021/acs.inorgchem.6b00381⟩
Journal articles hal-01407711v1

Four Gadolinium(III) Complexes Appended to a Porphyrin: A Water-Soluble Molecular Theranostic Agent with Remarkable Relaxivity Suited for MRI Tracking of the Photosensitizer

Angélique Sour , Sébastien Jenni , Ana Ortí-Suárez , Julie Schmitt , Valérie Heitz et al.
Inorganic Chemistry, 2016, 55 (9), pp.4545-4554. ⟨10.1021/acs.inorgchem.6b00381⟩
Journal articles hal-03102874v1

Associating a negatively charged GdDOTA-derivative to the Pittsburgh compound B for targeting Aβ amyloid aggregates

André Martins , Alexandre Oliveira , Jean-François Morfin , Douglas Laurents , Éva Tóth et al.
Journal of Biological Inorganic Chemistry, 2016, 21 (1), pp.83-99. ⟨10.1007/s00775-015-1316-9⟩
Journal articles hal-02069097v1

Interaction of PiB-Derivative Metal Complexes with Beta-Amyloid Peptides: Selective Recognition of the Aggregated Forms

André F. Martins , David M. Dias , Jean-François Morfin , Sara Lacerda , Douglas V. Laurents et al.
Chemistry - A European Journal, 2015, 21 (14), pp.5413-5422. ⟨10.1002/chem.201406152⟩
Journal articles hal-01171718v1

MRI Sensing of Neurotransmitters with a Crown Ether Appended Gd3+ Complex

Fatima Oukhatar , Sandra Même , William Même , Frédéric Szeremeta , Nikos K. Logothetis et al.
ACS Chemical Neuroscience, 2015, 6 (2), pp.219-225. ⟨10.1021/cn500289y⟩
Journal articles hal-01171764v1

A pyridine-based ligand with two hydrazine functions for lanthanide chelation: remarkable kinetic inertness for a linear, bishydrated complex

Célia S. Bonnet , Sophie Laine , Frédéric Buron , Gyula Tircsó , Agnès Pallier et al.
Inorganic Chemistry, 2015, 54 (12), pp.5991-6003. ⟨10.1021/acs.inorgchem.5b00804⟩
Journal articles hal-01196977v1

Stabilizing Divalent Europium in Aqueous Solution Using Size-Discrimination and Electrostatic Effects

Martín Regueiro-Figueroa , José Luis Barriada , Agnès Pallier , David Esteban-Gómez , Andrés De Blas et al.
Inorganic Chemistry, 2015, 54 (10), pp.4940-4952. ⟨10.1021/acs.inorgchem.5b00548⟩
Journal articles hal-01196972v1

Macrocyclic Gd(3+) Complexes with Pendant Crown Ethers Designed for Binding Zwitterionic Neurotransmitters.

Fatima Oukhatar , Hervé Meudal , Céline Landon , Nikos K Logothetis , Carlos Platas-Iglesias et al.
Chemistry - A European Journal, 2015, 21 (31), pp.11226-11237
Journal articles hal-01196981v1

H 4 octapa: Highly Stable Complexation of Lanthanide(III) Ions and Copper(II)

Ferenc Krisztián Kálmán , Andrea Végh , Martín Regueiro-Figueroa , Éva Tóth , Carlos Platas-Iglesias et al.
Inorganic Chemistry, 2015, 54 (5), pp.2345-2356. ⟨10.1021/ic502966m⟩
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X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations

Slávka Kaščáková , Alexandre Giuliani , Sara Lacerda , Agnès Pallier , Pascal Mercère et al.
Nano Research, 2015, 8 (7), pp.2373 - 2379. ⟨10.1007/s12274-015-0747-5⟩
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A bis(pyridine N-oxide) analogue of DOTA: relaxometric properties of the Gd(III) complex and efficient sensitization of visible and NIR-emitting lanthanide(III) cations including Pr(III) and Ho(III).

André F Martins , Svetlana V Eliseeva , Henrique F Carvalho , João M C Teixeira , Carlos T B Paula et al.
Chemistry - A European Journal, 2014, 20 (45), pp.14834-14845
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Nanozeolite-LTL with Gd(III) deposited in the large and Eu(III) in the small cavities as a magnetic resonance optical imaging probe.

Florian Mayer , Wuyuan Zhang , Thomas Brichart , Olivier Tillement , Célia S Bonnet et al.
Chemistry - A European Journal, 2014, 20 (12), pp.3358-3364. ⟨10.1002/chem.201304457⟩
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Cyclodextrin Polyrotaxanes as a Highly Modular Platform for the Development of Imaging Agents

Jean Wilfried Fredy , Jérémy Scelle , Aurélie Guenet , Elodie Morel , Ségolène Adam de beaumais et al.
Chemistry - A European Journal, 2014, 20 (35), pp.10915-10920. ⟨10.1002/chem.201403635⟩
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Agents de contraste pour l'IRM

Jean-François Morfin , Jean-Claude Beloeil , Éva Tóth
Techniques de l'Ingenieur, 2014, pp.AF6818-1 - AF6818-19
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Mechanistic studies of Gd$^{3+}$-based MRI contrast agents for Zn$^{2+}$ detection: towards rational design

Célia S. Bonnet , Fabien Caillé , Agnès Pallier , Jean-François Morfin , Stéphane Petoud et al.
Chemistry - A European Journal, 2014, 20 (35), pp.10959-10969. ⟨10.1002/chem.201403043⟩
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Gd(3+) complexes conjugated to Pittsburgh compound B: potential MRI markers of β-amyloid plaques.

André F Martins , Jean-François Morfin , Carlos F G C Geraldes , Éva Tóth
European Journal of Biochemistry, 2014, 19 (2), pp.281-295
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Radiolabeling and initial evaluation of [In-111]AML-1, a new probe for SPECT imaging of amyloid deposits

Nicolas Arlicot , Hélène Fourmy , Martin André , Johnny Vercouillie , Carlos Geraldes et al.
Journal of Labelled Compounds and Radiopharmaceuticals, 2013, 56 (supplément 1), pp.S307
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New tris-3,4-HOPO lanthanide complexes as potential imaging probes: complex stability and magnetic properties.

Ana Catarina Fernandes Mendonça , André F Martins , Andrea Melchior , Sérgio M Marques , Sílvia Chaves et al.
Dalton Transactions, 2013, 42 (17), pp.6046-57. ⟨10.1039/c2dt32237d⟩
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Lanthanide-Based, Near-Infrared Luminescent and Magnetic Lipoparticles: Monitoring Particle Integrity.

Sara Lacerda , Célia S Bonnet , Agnès Pallier , Sandrine Villette , Frédéric Foucher et al.
Small, 2013, 9 (16), pp.2662-2666. ⟨10.1002/smll.201201923⟩
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Amide conjugates of the DO3A-N-(alpha-amino)propionate ligand: leads for stable, high relaxivity Contrast Agents for MRI?

M.F. Ferreira , A.F. Martins , C.I.O. Martins , É. Tóth , T.B. Rodrigues et al.
Contrast Media and Molecular Imaging, 2013, 8 (1), pp.40-49. ⟨10.1002/cmmi.1492⟩
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Relaxometry Studies of a Highly Stable Nanoscale Metal–Organic Framework Made of Cu(II), Gd(III), and the Macrocyclic DOTP

Arnau Carné-Sánchez , Célia Bonnet , Inhar Imaz , Julia Lorenzo , Éva Tóth et al.
Journal of the American Chemical Society, 2013, 135 (47), pp.17711-17714. ⟨10.1021/ja4094378⟩
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Thermodynamic stability and relaxation studies of small, triaza-macrocyclic Mn(II) chelates.

Arsénio de Sá , Célia S Bonnet , Carlos F G C Geraldes , Éva Tóth , Paula M T Ferreira et al.
Dalton Transactions, 2013, 42 (13), pp.4522-32. ⟨10.1039/c2dt32496b⟩
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PiB-Conjugated, Metal-Based Imaging Probes: Multimodal Approaches for the Visualization of β-Amyloid Plaques

André F. Martins , Jean-François Morfin , Anna Kubícková , Vojtěch Kubícek , Frédéric Buron et al.
Planetary and Space Science, 2013, 4 (5), pp.436-440. ⟨10.1021/ml400042w⟩
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Lanthanide Complexes Formed with the Tri- and Tetraacetate Derivatives of Bis(aminomethyl)phosphinic Acid: Equilibrium, Kinetic and NMR Spectroscopic Studies

Gyula Tircsó , Ferenc Kálmán , Robert Pal , István Bányai , Tamas Varga et al.
European Journal of Inorganic Chemistry, 2012, 2012 (12), pp.2062-2073. ⟨10.1002/ejic.201101299⟩
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Tris(phosphonomethyl)cyclen Derivatives: Thermodynamic Stability, Kinetics, Solution Structure, and Relaxivity of Ln3+ Complexes

L.M.P. Lima , R. Degaldo , P. Hermann , R. Sevcik , P. Lubal et al.
European Journal of Inorganic Chemistry, 2012, 2012 (15), pp.2548-2559. ⟨10.1002/ejic.201101335⟩
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Manganese(II) Complexes as Potential Contrast Agents for MRI

Bohuslav Drahos , Ivan Lukes , Éva Tóth
European Journal of Inorganic Chemistry, 2012, 12 (SI), pp.1975-1986. ⟨10.1002/ejic.201101336⟩
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Pyridine-based lanthanide complexes combining MRI and NIR luminescence activities.

Célia S Bonnet , Frédéric Buron , Fabien Caillé , Chad M Shade , Bohuslav Drahoš et al.
Chemistry - A European Journal, 2012, 18 (5), pp.1419-31. ⟨10.1002/chem.201102310⟩
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Isoquinoline-based lanthanide complexes: bright NIR optical probes and efficient MRI agents.

Fabien Caillé , Célia S Bonnet , Frédéric Buron , Sandrine Villette , Lothar Helm et al.
Inorganic Chemistry, 2012, 51 (4), pp.2522-32. ⟨10.1021/ic202446e⟩
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Lanthanide complexes based on a diazapyridinophane platform containing picolinate pendants.

Adrián Roca-Sabio , Célia S Bonnet , Marta Mato-Iglesias , David Esteban-Gómez , Éva Tóth et al.
Inorganic Chemistry, 2012, 51 (20), pp.10893-10903. ⟨10.1021/ic301369z⟩
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Lanthanide(III) complexes that contain a self-immolative arm: potential enzyme responsive contrast agents for magnetic resonance imaging.

Thomas Chauvin , Susana Torres , Renato Rosseto , Jan Kotek , Bernard Badet et al.
Chemistry - A European Journal, 2012, 18 (5), pp.1408-18. ⟨10.1002/chem.201101779⟩
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Mn2+ complexes with 12-membered pyridine based macrocycles bearing carboxylate or phosphonate pendant arm: crystallographic, thermodynamic, kinetic, redox, and 1H/17O relaxation studies.

Bohuslav Drahoš , Jan Kotek , Ivana Císařová , Petr Hermann , Lothar Helm et al.
Inorganic Chemistry, 2011, 50 (24), pp.12785-801. ⟨10.1021/ic201935r⟩
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Influence of calcium-induced aggregation on the sensitivity of aminobis(methylenephosphonate)-containing potential MRI contrast agents.

Jörg Henig , Ilgar Mamedov , Petra Fouskova , Éva Tóth , Nikos K Logothetis et al.
Inorganic Chemistry, 2011, 50 (14), pp.6472-81. ⟨10.1021/ic1024235⟩
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A Pyrophosphate-Responsive Gadolinium(III) MRI Contrast Agent

Andrew J. Surman , Celia S. Bonnet , Mark P. Lowe , Gavin D. Kenny , Jimmy D. Bell et al.
Chemistry - A European Journal, 2011, 17 (1), pp.223-230. ⟨10.1002/chem.201001397⟩
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Efficient Access to C1-and C3-Functionalized Isoquinolines: Towards Potential Lanthanide Ligands

Fabien Caille , Frederic Buron , Éva Tóth , Franck Suzenet
European Journal of Organic Chemistry, 2011, 11, pp.2120-2127. ⟨10.1002/ejoc.201001691⟩
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Kinetics of Ga(NOTA) formation from weak Ga-citrate complexes.

Jean-François Morfin , Éva Tóth
Inorganic Chemistry, 2011, 50 (20), pp.10371-8. ⟨10.1021/ic201445e⟩
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Calcium-responsive paramagnetic CEST agents

Goran Angelovski , Thomas Chauvin , Rolf Pohmann , Nikos K. Logothetis , Éva Tóth et al.
Bioorganic and Medicinal Chemistry, 2011, 19 (3), pp.1097-1105. ⟨10.1016/j.bmc.2010.07.023⟩
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Macrocyclic Receptor Showing Extremely High Sr(II)/Ca(II) and Pb(II)/Ca(II) Selectivities with Potential Application in Chelation Treatment of Metal Intoxication

Raquel Ferreiros-Martinez , David Esteban-Gomez , Éva Tóth , Blas Andres De , Carlos Platas-Iglesias et al.
Inorganic Chemistry, 2011, 50 (8), pp.3772-3784. ⟨10.1021/ic200182e⟩
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Mn2+ complexes of 1-oxa-4,7-diazacyclononane based ligands with acetic, phosphonic and phosphinic acid pendant arms: Stability and relaxation studies

Bohuslav Drahoš , Miroslav Pniok , Jana Havlíčková , Jan Kotek , Ivana Císařová et al.
Dalton Transactions, 2011, 40 (39), pp.10131. ⟨10.1039/C1DT10543D⟩
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Dissociation kinetics of Mn2+ complexes of NOTA and DOTA

Bohuslav Drahoš , Vojtěch Kubíček , Celia ́ Bonnet , Petr Hermann , Ivan Lukeš et al.
Dalton Transactions, 2011, 40 (9), pp.1945. ⟨10.1039/c0dt01328e⟩
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Lanthanide complexes as imaging agents anchored on nano-sized particles of boehmite

Estefania Delgado-Pinar , M. Teresa Albelda , Juan C. Frias , Olga Barreiro , Emilio Tejera et al.
Dalton Transactions, 2011, 40 (24), pp.6451-6457. ⟨10.1039/c1dt10389j⟩
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Towards highly efficient, intelligent and bimodal imaging probes : novel approaches provided by lanthanide coordination chemistry

Célia Bonnet , Éva Tóth
Comptes Rendus. Chimie, 2010, 13 (6-7 Sp. Iss. SI), pp.700-714. ⟨10.1016/j.crci.2010.03.026⟩
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Gallium(III) Complexes of DOTA and DOTA-Monoamide: Kinetic and Thermodynamic Studies

Vojtech Kubicek , Jana Havlickova , Jan Kotek , Tircso Gyula , Petr Hermann et al.
Inorganic Chemistry, 2010, 49 (23), pp.10960-10969. ⟨10.1021/ic101378s⟩
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Macrocyclic Gd3+ Chelates Attached to a Silsesquioxane Core as Potential MRI Contrast Agents - Synthesis, Physicochemical Characterization and Stability Studies

Jorg Henig , Éva Tóth , Jorn Engelmann , Sven Gottschalk , Hermann A. Mayer et al.
Inorganic Chemistry, 2010, 49 (13), pp.6124-6138. ⟨10.1021/ic1007395⟩
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Lanthanide(III) complexes of 4,10-bis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane-1,7-diacetic acid (trans-H6do2a2p) in solution and in the solid state: structural studies along the series

Paula c. M. Campello , Sara Lacerda , Isabel c. Santos , Giovannia a. Pereira , Carlos F. G. C. Geraldes et al.
Chemistry - A European Journal, 2010, 16 (28), pp.8446-8465. ⟨10.1002/chem.201000320⟩
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Smart MR Imaging Agents Relevant to Potential Neurologic Applications

Célia Bonnet , Éva Tóth
American Journal of Neuroradiology, 2010, 31 (3), pp.401-409. ⟨10.3174/ajnr.A1753⟩
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Welcome to ‘Molecular Probes in Optical and Magnetic Resonance Imaging’

Éva Tóth , Stéphane Petoud
Future Medicinal Chemistry, 2010, 2 (3), pp.305-306. ⟨10.4155/fmc.10.7⟩
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Hydrophobic chromophore cargo in micellar structures: a different strategy to sensitize lanthanide cations

Célia Bonnet , Laurent Pellegatti , Frédéric Buron , Chad Shade , Sandrine Villette et al.
Chemical Communications, 2010, 46 (1), pp.124-126. ⟨10.1039/B918881A⟩
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Magnetic resonance imaging probes for sensing biologically relevant metal ions

Célia Bonnet , Éva Tóth
Future Medicinal Chemistry, 2010, 2 (3), pp.367-384. ⟨10.4155/fmc.09.161⟩
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Mn2+ Complexes with Pyridine-Containing 15-Membered Macrocycles : Thermodynamic, Kinetic, Crystallographic, and H-1/O-17 Relaxation Studies

Bohuslav Drahos , Jan Kotek , Petr Hermann , Ivan Lukes , Éva Tóth et al.
Inorganic Chemistry, 2010, 49 (7), pp.3224-3238. ⟨10.1021/ic9020756⟩
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Ga(III) complexes with DOTA-like ligand - thermodynamic and kinetic stability

Vojtech Kubicek , Petr Hermann , Eva Jakab-Toth
Nuclear Medicine and Biology, 2010, 37 (6), pp.680-680. ⟨10.1016/j.nucmedbio.2010.04.192⟩
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Molecular Recognition of Sialic Acid by Lanthanide(III) Complexes through Cooperative Two-Site Binding

Martin Regueiro-Figueroa , Kristina Djanashvili , David Esteban-Gomez , Thomas Chauvin , Éva Tóth et al.
Inorganic Chemistry, 2010, 49 (9), pp.4212-4223. ⟨10.1021/ic902461g⟩
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Synthesis, Characterization and Biological Evaluation of In(III) Complexes Anchored by DOTA-like Chelators Bearing a Quinazoline Moiety

Raquel Garcia , Vojtech Kubicek , Bohuslav Drahos , Lurdes Gano , Isabel C. Santos et al.
Mettalomics, 2010, 2 (8), pp.571-580. ⟨10.1039/c004797j⟩
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Densely packed Gd(III)-chelates with fast water exchange on a calix[4]arene scaffold: a potential MRI contrast agent

Daniel T. Schuhle , Miloslav Polasek , Ivan Lukes , Thomas Chauvin , Éva Tóth et al.
Dalton Transactions, 2010, 39 (1), pp.185-191. ⟨10.1039/b917673j⟩
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A novel tetraazamacrocycle bearing a thiol pendant arm for labeling biomolecules with radiolanthanides

Sara Lacerda , M. Paula Campello , Fernanda Marques , Lurdes Gano, , Vojtech Kubicek et al.
Dalton Transactions, 2009, 23, pp.4509-4518. ⟨10.1039/b820375j⟩
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A quinazoline-derivative DOTA-type gallium(III) complex for targeting epidermal growth factor receptors: synthesis, characterisation and biological studies

Raque Garcia , Petra Fousková , Lurdes Gano , Antonio Paulo , Paula Campello et al.
Journal of Biological Inorganic Chemistry, 2009, 14 (2), pp.261-271. ⟨10.1007/s00775-008-0446-8⟩
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Relaxation and luminescence studies on hydrated bipyridyl- and terpyridyl-based lanthanide complexes

Vojtech Kubicek , Anna Hamplova , Laurence Maribe , Samir Mameri , Raymond Ziessel et al.
Dalton Transactions, 2009, 43, pp.9466-9474. ⟨10.1039/b913084e⟩
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Design and function of metal complexes as contrast agents in MRI

Vojtech Kubicek , Éva Tóth
Advances in Inorganic Chemistry, 2009, 61, pp.63-129. ⟨10.16/S0898-8838⟩
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Stability, Water Exchange, and Anion Binding Studies on Lanthanide(III) Complexes with a Macrocyclic Ligand Based on 1,7-Diaza-12-crown-4: Extremely Fast Water Exchange on the Gd3+ Complex

Zoltan Palinkas , Adrian Roca-Sabio , Marta Mato-Iglesias , David Steban-Gomez , Carlos Platas-Iglesias et al.
Inorganic Chemistry, 2009, 48 (18), pp.8878-8889. ⟨10.1021/ic9011197⟩
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Gd(DO3A-N-alpha-aminopropionate): a versatile and easily available synthon with optimized water exchange for the synthesis of high relaxivity, targeted MRI contrast agents

Miguel Ferreira , Andre Martins , A. Martins Jose , Paula Ferreira , Éva Tóth et al.
Chemical Communications, 2009, 42, pp.6475-6477. ⟨10.1039/b912201j⟩
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Macrocyclic Receptor Exhibiting Unprecedented Selectivity for Light Lanthanides

Adrian Roca-Sabio , Marta Mato-Iglesias , David Esteban-Gomez , Éva Tóth , Andres de Blas et al.
Journal of the American Chemical Society, 2009, 131 (9), pp.3331-3341. ⟨10.1021/ja808534w⟩
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Noncovalent Functionalization of Carbon Nanotubes with Amphiphilic Gd3+ Chelates: Towards Powerful T1 and T2 MRI

Cyrille Richard , Bich-Thuy Doan , Jean-Claude Beloeil , Michel Bessodes , Éva Tóth et al.
Nano Letters, 2008, 8 (1), pp.232-236. ⟨10.1021/nl072509z⟩
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A benzene-core trinuclear GdIII complex: towards the optimization of relaxivity for MRI contrast agent applications at high magnetic field

João Bruno Livramento , Lothar Helm , Angélique Sour , Conlin O'Neil , André E. Merbach et al.
Dalton Transactions, 2008, 9, pp.1195-1202. ⟨10.1039/b717390c⟩
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Lanthanide complexes based on a 1,7-diaza-12-crown-4 platform containing picolinate pendants: A new structural entry for the design of magnetic resonance imaging contrast agents

M. Mato-Iglesias , A. Roca-Sabio , Z. Palinkas , D. Esteban-Gomez , C. Platas-Iglesias et al.
Inorganic Chemistry, 2008, 47 (17), pp.7840-7851. ⟨10.1021/ic800878x⟩
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Facile Synthesis and Relaxation Properties of Novel Bis-polyazamacrocyclic Gd3+ Complexes: an Attempt towards Calcium Sensitive MRI Contrast Agents

Anurag Mishra , Petra Fousková , Goran Angelovski , Edina Balogh , Anil K. Mishra et al.
Inorganic Chemistry, 2008, 47 (4), pp.1370-1381. ⟨10.1021/ic7017456⟩
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Detection of enzymatic activity by PARACEST MRI: a general approach to target a large variety of enzymes

Thomas Chauvin , Philippe Durand , Michèle Bernier , Hervé Meudal , Bich-Thuy Doan et al.
Angewandte Chemie International Edition, 2008, 47 (23), pp.4370-4372. ⟨10.1002/anie.200800809⟩
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Smart magnetic resonance imaging agents that sense extracellular calcium fluctuations

Goran Angelovski , Petra Fouskova , Ilgar Mamedov , Santiago Canals , Éva Tóth et al.
ChemBioChem, 2008, 9 (11), pp.1729-34. ⟨10.1002/cbic.200800165⟩
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Gd(III)-EPTPAC(16), a new self-assembling potential liver MRI contrast agent: in vitro characterization and in vivo animal imaging studies

Suzana Torres , M.I.M. Prata , Ana Santos , Joao P. Andre , Jose A. Martins et al.
NMR in Biomedicine, 2008, 21 (4), pp.322-336. ⟨10.1002/nbm.1194⟩
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Gadonanotubes as Ultrasensitive pH-Smart Probes for Magnetic Resonance Imaging

Keith B. Hartman , Sabrina Laus , Robert D. Bolskar , Raja Muthupillai , Lothar Helm et al.
Nano Letters, 2008, 8 (2), pp.415-419. ⟨10.1021/nl0720408⟩
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Pyridine-based lanthanide complexes: towards bimodal agents operating as near infrared luminescent and MRI reporters

L. Pellegatti , J. Zhang , B. Drahos , Sandrine Villette , Franck Suzenet et al.
Chemical Communications, 2008, 48CONTRAST AGENTS; LIGANDS; RATES; IONS; ACID, pp.6591-6593. ⟨10.1039/b817343e⟩
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Towards extracellular Ca2+ sensing by MRI: synthesis and calcium-dependent 1H and 17O relaxation studies of two novel bismacrocyclic Gd3+ complexes

Kirti Dhingra , Petra Fousková , Goran Angelovski , Martin E. Maier , Nikos K. Logothetis et al.
Journal of Biological Inorganic Chemistry, 2008, 13 (1), pp.35-46. ⟨10.1007/s00775-007-0296-9⟩
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Lanthanide-Based Conjugates as Polyvalent Probes for Biological Labeling

Stéphanie Claudel-Gillet , Jérôme Steibel , Nicolas Weibel , Thomas Chauvin , Marc Port et al.
European Journal of Inorganic Chemistry, 2008, 18, pp.2856 - 2862. ⟨10.1002/ejic.200800269⟩
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In vivo MRI assessment of a novel GdIII-based contrast agent designed for high magnetic field applications

Paulo Loureiro de Sousa , João Bruno Livramento , Lothar Helm , André E Merbach , William Même et al.
Contrast Media and Molecular Imaging, 2008, 3 (2), pp.78 - 85. ⟨10.1002/cmmi.233⟩
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Physicochemical and MR imaging characterisation of Gd3+ loaded PAMAM and hyperbranched dendrimers

Z. Jászberényi , L. Moriggi , P. Schmidt , C. Weidensteiner , R. Kneuer et al.
Journal of Biological Inorganic Chemistry, 2007, 12, pp.406-420
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Gadolinium(III) Complexes of Mono- and Diethyl Esters of Monophosphonic Acid Analogue of DOTA as Potential MRI Contrast Agents: Solution Structures and Relaxometric Studies

P. Lebduskova , P. Hermann , L. Helm , É. Tóth , J. Kotek et al.
Dalton Transactions, 2007, 4, pp.493-501. ⟨10.1039/b612876a⟩
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Monopropionate analogues of DOTA4– and DTPA5–: kinetics of formation and dissociation of their lanthanide(iii) complexes

Edina Balogh , Raphaël Tripier , Petra Fousková , Felipe Reviriego , Henri Handel et al.
Dalton Transactions, 2007, 32, ⟨10.1039/B706353A⟩
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H5EPTPACH2OH: Synthesis, relaxometric characterization and H-1 NMR studies of the solution dynamics of its Ln(III) complexes

Ja. Martins , Jp. André , Ga. Pereira , R. Kiraly , E. Brücher et al.
European Journal of Inorganic Chemistry, 2007, 35, pp.5489-5499. ⟨10.1002/ejic.200700435⟩
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Dinuclear Complexes Formed with the Triazacyclononane Derivative ENOTA4-. High Pressure 17O NMR evidence of an associative water exchange on [MnII2(ENOTA)(H2O)2]

E. Balogh , Z. He , W. Hsieh , S. Liu , Éva Tóth et al.
Inorganic Chemistry, 2007, 46 (1), pp.238-250
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Understanding paramagnetic relaxation phenomena in water-soluble gadofullerenes

S. Laus , B. Sitharaman , É. Tóth , Rd. Bolskar , Lm. Helm et al.
The Journal of physical chemistry, 2007, 111 (15), pp.5633-5639
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Unexpected Aggregation of Neutral, Xylene-Cored Dinuclear Gd(III) Chelates in Aqueous Solution

Jérôme Costa , Edina Balogh , Véronique Turcry , Raphaël Tripier , Michel Le Baccon et al.
Chemistry - A European Journal, 2006, 12 (26), pp.6841 - 6851. ⟨10.1002/chem.200501335⟩
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First in vivo MRI assessment of a self-assembled metallostar compound endowed with a remarkable high field relaxivity

J.B. Livramento , C. Weidensteiner , M.I.M. Prata , P.R. Allegrini , Geraldes C.F.G.C. et al.
Contrast Media and Molecular Imaging, 2006, 1, pp.30-39. ⟨10.1002/cmmi.92⟩
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A Starburst-Shaped Heterometallic Compound Incorporating Six Densely Packed Gd3+ Ions

João Bruno Livramento , Angélique Sour , Alain Borel , André Merbach , Éva Tóth et al.
Chemistry - A European Journal, 2006, 12 (4), pp.989-1003. ⟨10.1002/chem.200500969⟩
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Positively charged GdIII cryptates: slow, associative water exchange

László Burai , Éva Tóth , Hervé Bazin , Meriem Benmelouka , Zoltán Jászberényi et al.
Dalton Transactions, 2006, 28 (4), pp.629-634. ⟨10.1039/b506700f⟩
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Pyridine and phosphonate containing acyclic ligands for stable lanthanide complexation. Extremely fast water exchange on the GdIII chelates.

E. Balogh , M. Mato-Iglesias , C. Platas-Iglesias , É. Tóth , K. Djanashvili et al.
Inorganic Chemistry, 2006, 45 (21), pp.8719-8728. ⟨10.1021/ic0604157S0020-1669(06)00415-0⟩
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Phosphinic derivative of DTPA conjugated to a G5 PAMAM dendrimer: an (17)O and (1)H relaxation study of its Gd(iii) complex

P. Lebdušková , A. Sour , L. Helm , É. Tóth , J. Kotek et al.
Dalton Transactions, 2006, 28, pp.3399-3406. ⟨10.1039/b517847a⟩
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Supramolecular Assembly of an Amphiphilic GdIII Chelate: Tuning the Reorientational Correlation Time and the Water Exchange Rate

Susana Torres , José Lauro Martins , João André , Carlos Geraldes , A.E Merbach et al.
Chemistry - A European Journal, 2006, 12 (3), pp.940-948. ⟨10.1002/chem.200500551⟩
Journal articles hal-02080311v1
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Pyridine and phosphonate containing ligands for stable lanthanide complexation. An experimental and theoretical study to assess the solution structure

M. Mato-Iglesias , E. Balogh , C. Platas-Iglesias , É. Tóth , A. de Blas et al.
Dalton Transactions, 2006, 45, pp.5404-5415. ⟨10.1039/b611544f⟩
Journal articles hal-00512396v1

Rotational Dynamics Account for pH-Dependent Relaxivities of PAMAM Dendrimeric, Gd-Based Potential MRI Contrast Agents

Sabrina Laus , Angélique Sour , Robert Ruloff , Éva Tóth , André Merbach et al.
Chemistry - A European Journal, 2005, 11 (10), pp.3064-3076. ⟨10.1002/chem.200401326⟩
Journal articles hal-02080342v1

The highest water exchange rate ever measured for a Gd(iii) chelate

Marta Mato-Iglesias , Carlos Platas-Iglesias , Kristina Djanashvili , Joop Peters , Éva Tóth et al.
Chemical Communications, 2005, 37, pp.4729. ⟨10.1039/b508180g⟩
Journal articles hal-02080307v1

NMR relaxivity of Ln3+-based zeolite-type materials

G. Pereira , D. Ananias , J. Rocha , V. Amaral , R. Muller et al.
Journal of Materials Chemistry, 2005, 15 (35-36), pp.3832-3837. ⟨10.1039/B504082E⟩
Journal articles hal-02080324v1

Separation and Characterization of the Two Diastereomers for [Gd(DTPA-bz-NH 2 )(H 2 O)] 2- , a Common Synthon in Macromolecular MRI Contrast Agents: Their Water Exchange and Isomerization Kinetics

László Burai , Éva Tóth , Angélique Sour , André Merbach
Inorganic Chemistry, 2005, 44 (10), pp.3561-3568. ⟨10.1021/ic048645d⟩
Journal articles hal-02080400v1

Destroying Gadofullerene Aggregates by Salt Addition in Aqueous Solution of Gd@C 60 (OH) x and Gd@C 60 [C(COOH 2 )] 10

Sabrina Laus , Balaji Sitharaman , Éva Tóth , Robert Bolskar , Lothar Helm et al.
Journal of the American Chemical Society, 2005, 127 (26), pp.9368-9369. ⟨10.1021/ja052388+⟩
Journal articles hal-02080318v1

Fine-tuning water exchange on GdIII poly(amino carboxylates) by modulation of steric crowding

Zoltán Jászberényi , Angélique Sour , Éva Tóth , Meriem Benmelouka , André Merbach et al.
Dalton Transactions, 2005, 16, pp.2713. ⟨10.1039/b506702b⟩
Journal articles hal-02080315v1

Synthesis and complexation properties of DTPA-N,N″-bis[bis(n-butyl)]-N′-methyl-tris(amide). Kinetic stability and water exchange of its Gd 3+ complex

Z. Jászberényi , É. Tóth , T. Kálai , R. Király , L. Burai et al.
Dalton Transactions, 2005, 4, pp.694-701. ⟨10.1039/b417272h⟩
Journal articles hal-02080396v1

Water-Soluble Gadofullerenes: Toward High-Relaxivity, pH-Responsive MRI Contrast Agents

Éva Tóth , Robert Bolskar , Alain Borel , Gabriel Gonzalez , Lothar Helm et al.
Journal of the American Chemical Society, 2005, 127 (2), pp.799-805. ⟨10.1021/ja044688h⟩
Journal articles hal-02080406v1

Dinuclear, Bishydrated Gd III Polyaminocarboxylates with a Rigid Xylene Core Display Remarkable Proton Relaxivities

Jérôme Costa , Éva Tóth , Lothar Helm , André Merbach
Inorganic Chemistry, 2005, 44 (13), pp.4747-4755. ⟨10.1021/ic0500309⟩
Journal articles hal-02080333v1

Lanthanide(III) Chelates of DTPA Bis(amide) Glycoconjugates: Potential Imaging Agents Targeted at the Asyaloglycoprotein Receptor

Paula Baía , João André , Carlos Geraldes , José Lauro Martins , André Merbach et al.
European Journal of Inorganic Chemistry, 2005, 2005 (11), pp.2110-2119. ⟨10.1002/ejic.200400766⟩
Journal articles hal-02080416v1

Kinetics of formation and dissociation of lanthanide(III) complexes with the 13-membered macrocyclic ligand TRITA

E. Balogh , Raphaël Tripier , R. Ruloff , É. Tóth
Dalton Transactions, 2005, 6, pp.1058-1065. ⟨10.1039/b418991d⟩
Journal articles hal-01763750v1

Superparamagnetic gadonanotubes are high-performance MRI contrast agents

Balaji Sitharaman , Kyle Kissell , Keith Hartman , Lesa Tran , Andrei Baikalov et al.
Chemical Communications, 2005, 31, pp.3915. ⟨10.1039/b504435a⟩
Journal articles hal-02080330v1

High Relaxivity Confined to a Small Molecular Space: A Metallostar-Based, Potential MRI Contrast Agent

João Bruno Livramento , Éva Tóth , Angélique Sour , Alain Borel , André Merbach et al.
Angewandte Chemie International Edition, 2005, 44 (10), pp.1480-1484. ⟨10.1002/anie.200461875⟩
Journal articles hal-02080412v1

Enhanced imaging properties of a GdIII complex with unusually large relaxivity

Nicolas Fatin-Rouge , Éva Tóth , Réto Meuli , Jean-Claude Bunzli
Journal of Alloys and Compounds, 2004, 374 (1-2), pp.298-302. ⟨10.1016/j.jallcom.2003.11.125⟩
Journal articles hal-02080428v1

Lanthanide( III ) Complexes of DOTA-Glycoconjugates: A Potential New Class of Lectin-Mediated Medical Imaging Agents

João André , Carlos Geraldes , José Lauro Martins , André Merbach ,