Florence Fauvelle

47
Documents
Affiliations actuelles
  • [GIN] Grenoble Institut des Neurosciences (GIN)
  • IRMaGe (IRMaGe)
Contact

Domaines de recherche

Sciences du Vivant [q-bio] Sciences de l'ingénieur [physics]

Compétences

Metabolomique par RMN Métabolisme cérébral RMN biomédicale Quantificatioin Epilepsie Maladie de Parkinson

Publications

Publications

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A metabolic biomarker predicts Parkinson’s disease at the early stages in patients and animal models

David Mallet , Thibault Dufourd , Mélina Decourt , Carole Carcenac , Paola Bossù et al.
The Journal of clinical investigation, 2022, 132 (4), pp.146400. ⟨10.1172/JCI146400⟩
Article dans une revue hal-03577368 v1

The metabolite succinate inhibits influenza virus replication through succinylation and nuclear retention of the viral nucleoprotein

Adeline Cezard , Antoine Guillon , Deborah Bréa-Diakite , Alan Wacquiez , Thomas Baranek et al.
ERJ Open Research, 2022, 8, pp.119. ⟨10.1183/23120541.lsc-2022.119⟩
Article dans une revue hal-04494773 v1
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Re-routing Metabolism by the Mitochondrial Pyruvate Carrier Inhibitor MSDC-0160 Attenuates Neurodegeneration in a Rat Model of Parkinson’s Disease

David Mallet , Raphael Goutaudier , Emmanuel Barbier , Sebastien Carnicella , Jerry Colca et al.
Molecular Neurobiology, 2022, 59 (10), pp.6170-6182. ⟨10.1007/s12035-022-02962-9⟩
Article dans une revue hal-03776152 v1
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Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein

Antoine Guillon , Deborah Bréa-Diakite , Adeline Cezard , Alan Wacquiez , Thomas Baranek et al.
EMBO Journal, 2022, 41 (12), pp.e108306. ⟨10.15252/embj.2021108306⟩
Article dans une revue hal-03687124 v2
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The metabolic reprogramming in acute myeloid leukemia patients depends on their genotype and is a prognostic marker

Caroline Lo Presti , Florence Fauvelle , Marie-Christine Jacob , Julie Mondet , Pascal Mossuz
Blood Advances, 2021, 5 (1), pp.156-166. ⟨10.1182/bloodadvances.2020002981⟩
Article dans une revue hal-03110491 v1
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In vivo characterization of physiological and metabolic changes related to isocitrate dehydrogenase 1 mutation expcression by multiparametric MRI and MRS in a rat model with orthotopically grafted human-derived glioblastoma cell lines

Alexandra Clément , Matthieu Doyen , Florence Fauvelle , Gabriela Hossu , Bailiang Chen et al.
NMR in Biomedicine, 2021, 34 (6), pp.e4490. ⟨10.1002/nbm.4490⟩
Article dans une revue hal-03159567 v1

A 12‐month pilot study outcomes of vagus nerve stimulation in Crohn's disease

Valérie Sinniger , Sonia Pellissier , Florence Fauvelle , Candice Trocmé , Dominique Hoffmann et al.
Neurogastroenterology & Motility, 2020, 32 (10), ⟨10.1111/nmo.13911⟩
Article dans une revue hal-02993026 v1

The differential activation of metabolic pathways in leukemic cells depending on their genotype and micro-environmental stress

Caroline Lo Presti , Florence Fauvelle , Julie Mondet , Pascal Mossuz
Metabolomics, 2020, 16 (1), ⟨10.1007/s11306-020-1633-z⟩
Article dans une revue hal-02993069 v1
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Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells by modulating metabolism and death pathways

Jonathan Vial , Paul Huchedé , S. Fagault , F. Basset , M. Rossi et al.
Cell Death Discovery, 2020, 6 (1), pp.64. ⟨10.1038/s41420-020-00302-1⟩
Article dans une revue hal-02993062 v1
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In vivo γ‐aminobutyric acid increase as a biomarker of the epileptogenic zone: An unbiased metabolomics approach

Sophie Hamelin , Vasile Stupar , Lucile Mazière , Jia Guo , Wafae Labriji et al.
Epilepsia, 2020, 62 (1), pp.163-175. ⟨10.1111/epi.16768⟩
Article dans une revue inserm-04693171 v1
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LKB1 specifies neural crest cell fates through pyruvate-alanine cycling

Anca Radu , Sakina Torch , Florence Fauvelle , Karin Pernet-Gallay , Anthony Lucas et al.
Science Advances , 2019, 5 (7), pp.eaau5106. ⟨10.1126/sciadv.aau5106⟩
Article dans une revue hal-02328640 v1

High-Resolution Magic Angle Spinning NMR-Based Metabolomics Revealing Metabolic Changes in Lung of Mice Infected with P. aeruginosa Consistent with the Degree of Disease Severity

Audrey Legouëllec , Oriane Moyne , Elodie Meynet , Bertrand Toussaint , Florence Fauvelle
Journal of Proteome Research, 2018, 17 (10), pp.3409-3417. ⟨10.1021/acs.jproteome.8b00306⟩
Article dans une revue hal-02319486 v1

Effect of organochlorine pesticides exposure on the maize root metabolome assessed using high-resolution magic-angle spinning $^1$H NMR spectroscopy

Claire Blondel , Farid Khelalfa , Stéphane Reynaud , Florence Fauvelle , Muriel Raveton
Environmental Pollution, 2016, 214, pp.539 - 548. ⟨10.1016/j.envpol.2016.04.057⟩
Article dans une revue hal-04695364 v1

Assessing Susceptibility to Epilepsy in Three Rat Strains Using Brain Metabolic Profiling Based on HRMAS NMR Spectroscopy and Chemometrics

Florence Fauvelle , Julien Boccard , Fanny Cavarec , Antoine Depaulis , Colin Deransart
Journal of Proteome Research, 2015, 14 (5), pp.2177-2189. ⟨10.1021/pr501309b⟩
Article dans une revue hal-02430578 v1

Impact of manganese on the hippocampus metabolism in the context of MEMRI: a proton HRMAS MRS study

A. Daoust , E. Barbier , S. Bohic , V. Stupar , S. Maunoir-Regimbal et al.
Toxicology Research, 2015, 4 (2), pp.376-384. ⟨10.1039/c4tx00135d⟩
Article dans une revue hal-02430582 v1

Differences in prefrontal cortex GABA/glutamate ratio after acute restraint stress in rats are associated with specific behavioral and neurobiological patterns

J-B Drouet , Florence Fauvelle , S Maunoir-Regimbal , N Fidier , R Maury et al.
Neuroscience, 2015, 285, pp.155 - 165. ⟨10.1016/j.neuroscience.2014.10.058⟩
Article dans une revue hal-04695369 v1

The three glioma rat models C6, F98 and RG2 exhibit different metabolic profiles: in vivo 1H MRS and ex vivo 1H HRMAS combined with multivariate statistics

Nicolas Coquery , Vasile Stupar , Regine Farion , Séverine Maunoir-Regimbal , Emmanuel L. Barbier et al.
Metabolomics, 2015, 11 (6), pp.1834-1847. ⟨10.1007/s11306-015-0835-2⟩
Article dans une revue hal-02430555 v1

Therapeutic and preventive effects of methylene blue on Alzheimer's disease pathology in a transgenic mouse model

Veronique Paban , C. Manrique , M Filali , S. Maunoir-Regimbal , F. Fauvelle et al.
Neuropharmacology, 2014, 76, pp.68-79. ⟨10.1016/j.neuropharm.2013.06.033⟩
Article dans une revue hal-02553749 v1
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Prediction of Neuroprotective Treatment Efficiency Using a HRMAS NMR-Based Statistical Model of Refractory Status Epilepticus on Mouse: A Metabolomic Approach Supported by Histology

Florence Fauvelle , Pierre Carpentier , Frederic Dorandeu , Annie Foquin , Guy Testylier
Journal of Proteome Research, 2012, 11 (7), pp.3782 - 3795. ⟨10.1021/pr300291d⟩
Article dans une revue hal-04695381 v1

Metyrapone effects on systemic and cerebral energy metabolism

Jean-Baptiste Drouet , Florence Fauvelle , Cécile Batandier , André Peinnequin , Antonia Alonso et al.
European Journal of Pharmacology, 2012, 682 (1-3), pp.92 - 98. ⟨10.1016/j.ejphar.2012.02.025⟩
Article dans une revue istex hal-01930851 v1

Metyrapone effects on systemic and cerebral energy metabolism

Jean-Baptiste Drouet , Florence Fauvelle , Cécile Batandier , André Peinnequin , Antonia Alonso et al.
European Journal of Pharmacology, 2012, 682, pp.92 - 98. ⟨10.1016/j.ejphar.2012.02.025⟩
Article dans une revue istex hal-04705595 v1

Optimization of metabolite basis sets prior to quantitation in magnetic resonance spectroscopy: an approach based on quantum mechanics

A Lazariev , Abdul-Rahman Allouche , M. Aubert-Frécon , F. Fauvelle , M. Piotto et al.
Measurement Science and Technology, 2011, 22 (11), ⟨10.1088/0957-0233/22/11/114020⟩
Article dans une revue istex hal-01674000 v1

In vivo biodistribution and biological impact of injected carbon nanotubes using magnetic resonance techniques

Achraf Al Faraj , F. Fauvelle , N. Luciani , Ghislaine Lacroix , Yannick Cremillieux et al.
International Journal of Nanomedicine, 2011, 6, pp.351-361. ⟨10.2147/IJN.S16653⟩
Article dans une revue ineris-00963286 v1

In vivo proton HR-MAS NMR metabolic profile of the freshwater cladoceran Daphnia magna

A. Bunescu , Jeanne Garric , B. Vollat , E. Canet Soulas , D. Graveron Demilly et al.
Molecular BioSystems, 2010, 6, pp.121-125
Article dans une revue hal-02593144 v1

Age‐related changes in metabolic profiles of rat hippocampus and cortices

Véronique Paban , Florence Fauvelle , Béatrice Alescio-Lautier
European Journal of Neuroscience, 2010, 31 (6), pp.1063-1073. ⟨10.1111/j.1460-9568.2010.07126.x⟩
Article dans une revue istex hal-04695558 v1

In vivo proton HRMAS NMR metabolic profile of the freshwater cladoceran Daphnnia magna

A. Bunescu , J. Garric , B. Vollat , E. Canet-Soulas , D. Graveron-Demilly et al.
Molecular BioSystems, 2009, (in--press)
Article dans une revue hal-00443174 v1

Density functional theory calculations of the nuclear magnetic resonance spin-Hamiltonian parameters for two polyamines of prostate tissue: spermidine and spermine

Z Atieh , Abdul-Rahman Allouche , D. Graveron-Demilly , F. Fauvelle , M. Aubert-Frécon
Measurement Science and Technology, 2009, 20 (10), ⟨10.1088/0957-0233/20/10/104024⟩
Article dans une revue istex hal-01674018 v1

Changes in mouse brain metabolism following a convulsive dose of soman: A proton HRMAS NMR study

Florence Fauvelle , F Dorandeu , P Carpentier , A Foquin , H Rabeson et al.
Toxicology, 2009, 267 (1 - 3), pp.99 - 111. ⟨10.1016/j.tox.2009.10.026⟩
Article dans une revue istex hal-04695389 v1

Physicochemical properties and membrane interactions of anti-apoptotic derivatives 2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine depending on the hydroxyalkylamino side chain length and conformation: An NMR and ESR study

Sébastien Follot , Jean-Claude Debouzy , David Crouzier , Cécile Enguehard-Gueiffier , Alain Gueiffier et al.
European Journal of Medicinal Chemistry, 2009, 44 (9), pp.3509-3518. ⟨10.1016/j.ejmech.2008.12.026⟩
Article dans une revue istex hal-04695565 v1

DFT calculations of NMR spin-hamiltonian parameters for two polyamines of prostate tissue: Spermidine and spermine

Z. Atieh , A. R. Allouche , D. Graveron-Demilly , F. Fauvelle , M. Aubert-Frécon
Measurement Science and Technology, 2009, 20, (in-press)
Article dans une revue hal-00443119 v1
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In vivo proton HR-MAS NMR metabolic profile of the freshwater cladoceran Daphnia magna

Andrei Bunescu , Jeanne Garric , Bernard Vollat , Emmanuelle Canet-Soulas , Danielle Graveron-Demilly et al.
Molecular BioSystems, 2009, 6 (1), pp.121 - 125. ⟨10.1039/b915417e⟩
Article dans une revue inserm-04693201 v1

Quantitation with QUEST of brain HRMAS-NMR signals: Application to metabolic disorders in experimental epileptic seizures

H. Rabeson , F. Fauvelle , G. Testylier , A. Foquin , P. Carpentier et al.
Magnetic Resonance in Medicine, 2008, 59 (6), pp.1266--1273
Article dans une revue hal-00443416 v1

Theoretical and experimental investigation of the $^1$H NMR spectrum of putrescine

A R Allouche , D Graveron-Demilly , Florence Fauvelle , M Aubert-Frécon
Chemical Physics Letters, 2008, 466, pp.219 - 222. ⟨10.1016/j.cplett.2008.10.052⟩
Article dans une revue hal-04705618 v1

Theoretical and experimental investigation of the 1H NMR spectrum of putrescine

A. R. Allouche , D. Graveron-Demilly , F. Fauvelle , M. Aubert-Frécon
Chemical Physics Letters, 2008, 466 (4-6), pp.219--222
Article dans une revue hal-00443106 v1

Quantitation for in vivo and ex vivo NMR Spectroscopy

H. Rabeson , H. Ratiney , F. Fauvelle , C. Cudalbu , S. Cavassila et al.
Journal of Optoelectronics and Advanced Materials, 2007, 9, pp.505--511
Article dans une revue hal-00443417 v1

Cation Complexation Properties of Hexakis(2- O -methyl-3,6-anhydro)-α-cyclodextrin: A 1 H NMR Study

Florence Fauvelle , A. Gadelle , J. Debouzy , C. Baudin , B. Perly
Supramolecular Chemistry, 2006, 11 (3), pp.233-237. ⟨10.1080/10610270008049133⟩
Article dans une revue hal-04695633 v1

Synthesis of Polyfused Heterocycle Derivatives Containing the Dipyridoimidazole Core by Friedländer’s Reaction: Access to Analogs of Ellipticine

Emmanuel Moreau , Jean-Claude Teulade , Nicolas Desbois , Jean-Michel J.-M. Chezal , Florence Fauvelle et al.
Heterocycles, 2005, 65 (5), ⟨10.3987/COM-05-10354⟩
Article dans une revue hal-01677674 v1
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2,3-Diarylimidazo[1,2-a]pyridines as potential inhibitors of UV-induced keratinocytes apoptosis: synthesis, pharmacological properties and interactions with model membranes and oligonucleotides by NMR.

Cécile Enguehard-Gueiffier , Florence Fauvelle , Jean-Claude Debouzy , André Peinnequin , Isabelle Thery et al.
European Journal of Pharmaceutical Sciences, 2005, 24 (2-3), pp.219-27. ⟨10.1016/j.ejps.2004.10.009⟩
Article dans une revue inserm-00410561 v1

Cation complexing 2-O-alkylated, 3,6-anhydro-α-cyclodextrins: the side-chain length governs physicochemical properties and practical applications

J.Y. Pailler , A. Gadelle , Florence Fauvelle , V. Dabouis , D. Crouzier et al.
Journal of Drug Delivery Science and Technology, 2005, 15 (6), pp.419-426. ⟨10.1016/S1773-2247(05)50082-0⟩
Article dans une revue hal-04695694 v1

Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization

Karine Laulagnier , Claude Motta , Safouane Hamdi , Sébastien Roy , Florence Fauvelle et al.
Biochemical Journal, 2004, 380 (1), pp.161-171. ⟨10.1042/BJ20031594⟩
Article dans une revue hal-04695570 v1

Acidic Derivative of Per(3,6-anhydro)-α-cyclodextrin: Preparation and a First Evaluation of Its Affinity for Lanthanides by 1H NMR

Florence Fauvelle , A. Gadelle , Y. Pailler , S. Aous , J.C. Debouzy
Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2002, 42 (3/4), pp.203-207. ⟨10.1023/A:1016063103736⟩
Article dans une revue istex hal-04695606 v1

High-resolution 1H-NMR spectroscopy and beyond to explore plant metabolome

Dominique D. Rolin , Catherine Deborde , Mickael M. Maucourt , Cécile Cabasson , Florence Fauvelle et al.
Metabolomics Coming of Age with its Technological Diversity, 67 (1ère éd.), Elsevier Ltd, 693 p., 2013, Advances in Botanical Research, 978-0-12-397922-3. ⟨10.1016/B978-0-12-397922-3.00001-0⟩
Chapitre d'ouvrage hal-02811296 v1