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Investigation of equine testis contribution to vitamin D bioactivation
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Christelle Delalande
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Juliette Cognié
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Fabrice Reigner
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Functionalized Nanogels with Endothelin-1 and Bradykinin Receptor Antagonist Peptides Decrease Inflammatory and Cartilage Degradation Markers of Osteoarthritis in a Horse Organoid Model of Cartilage
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Frédéric Cassé
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Seng Manivong
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Romain Contentin
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Florence Legendre
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Tumor Suppressive Role of miR-342-5p and miR-491-5p in Human Osteosarcoma Cells
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Manon Jammes
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Françoise Rédini
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Laurent Poulain
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Christophe Denoyelle
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Marine Collagen Hydrolysates Downregulate the Synthesis of Pro-Catabolic and Pro-Inflammatory Markers of Osteoarthritis and Favor Collagen Production and Metabolic Activity in Equine Articular Chondrocyte Organoids
Bastien Bourdon
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Romain Contentin
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Frédéric Cassé
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Chloé Maspimby
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Sarah Oddoux
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Evaluation of Allogeneic Bone-Marrow-Derived and Umbilical Cord Blood-Derived Mesenchymal Stem Cells to Prevent the Development of Osteoarthritis in An Equine Model
Lélia Bertoni
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Sandrine Jacquet
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Thomas Branly
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Mélanie Desancé
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Florence Legendre
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Tumor Suppressive Role of miR-342-5p in Human Chondrosarcoma Cells and 3D Organoids
Clément Veys
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Abderrahim Benmoussa
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Romain Contentin
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Amandine Duchemin
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Emilie Brotin
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An experimentally induced osteoarthritis model in horses performed on both metacarpophalangeal and metatarsophalangeal joints: Technical, clinical, imaging, biochemical, macroscopic and microscopic characterization
Lélia Bertoni
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Sandrine Jacquet
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Thomas Branly
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Florence Legendre
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Mélanie Desancé
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Regulation of extracellular matrix synthesis by shell extracts from the marine bivalve Pecten maximus in human articular chondrocytes - Application for cartilage engineering.
Mouloud Bouyoucef
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Rodolphe Rakic
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Tangni Gómez-Leduc
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Thomas Latire
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Frédéric Marin
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Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy
Mélanie Desancé
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Romain Contentin
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Lélia Bertoni
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Tangni Gómez-Leduc
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Thomas Branly
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Enhanced chondrogenesis of bone marrow-derived stem cells by using a combinatory cell therapy strategy with BMP-2/TGF-β1, hypoxia, and COL1A1/HtrA1 siRNAs
Florence Legendre
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David Ollitrault
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Tangni Gómez-Leduc
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Mouloud Bouyoucef
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Magalie Hervieu
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RNA Interference and BMP-2 Stimulation Allows Equine Chondrocytes Redifferentiation in 3D-Hypoxia Cell Culture Model: Application for Matrix-Induced Autologous Chondrocyte Implantation
Rodolphe Rakic
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Bastien Bourdon
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Magalie Hervieu
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Thomas Branly
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Florence Legendre
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Shell extracts of the edible mussel and oyster induce an enhancement of the catabolic pathway of human skin fibroblasts, in vitro
Thomas Latire
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Florence Legendre
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Mouloud Bouyoucef
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Frédéric Marin
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Franck Carreiras
Journal articles
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Hypoxia Is a Critical Parameter for Chondrogenic Differentiation of Human Umbilical Cord Blood Mesenchymal Stem Cells in Type I/III Collagen Sponges
Tangni Gómez-Leduc
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Mélanie Desancé
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Magalie Hervieu
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Florence Legendre
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David Ollitrault
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Characterization and use of Equine Bone Marrow Mesenchymal Stem Cells in Equine Cartilage Engineering. Study of their Hyaline Cartilage Forming Potential when Cultured under Hypoxia within a Biomaterial in the Presence of BMP-2 and TGF-ß1
Thomas Branly
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Lélia Bertoni
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Romain Contentin
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Rodolphe Rakic
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Tangni Gómez-Leduc
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hal-02186824v1
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Chondrogenic commitment of human umbilical cord blood-derived mesenchymal stem cells in collagen matrices for cartilage engineering
Tangni Gómez-Leduc
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Magalie Hervieu
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Florence Legendre
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Mouloud Bouyoucef
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Nicolas Gruchy
Journal articles
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Reduced NF- κ B activity is observed in dermal fibroblasts from black-skinned African individuals
Nicolas Bigot
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Tangni Gómez-Leduc
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Magalie Hervieu
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Fanny Gallienne
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Thierry Oddos
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BMP-2, hypoxia, and COL1A1/HtrA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes
D. Ollitrault
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F. Legendre
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C. Drougard
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M. Briand
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H. Benateau
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Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells
Séverine Cruet-Hennequart
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Carole Drougard
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Georgina Shaw
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Florence Legendre
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Magali Demoor
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In vitro engineering of human 3D chondrosarcoma: a preclinical model relevant for investigations of radiation quality impact
Dounia Hamdi
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Sofia Barbieri
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François Chevalier
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Jean-Emmanuel Groetz
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Florence Legendre
Journal articles
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Shell Extracts from the Marine Bivalve Pecten maximus Regulate the Synthesis of Extracellular Matrix in Primary Cultured Human Skin Fibroblasts
Thomas Latire
,
Florence Legendre
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Nicolas Bigot
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Ludovic Carduner
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Sabrina Kellouche
Journal articles
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Cartilage tissue engineering: Molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction
Magali Demoor
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David Ollitrault
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Tangni Gómez-Leduc
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Mouloud Bouyoucef
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Magali Hervieu
Journal articles
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Enhanced Hyaline Cartilage Matrix Synthesis in Collagen Sponge Scaffolds by Using siRNA to Stabilize Chondrocytes Phenotype Cultured with Bone Morphogenetic Protein-2 Under Hypoxia
Florence Legendre
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David Ollitrault
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Magalie Hervieu
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Catherine Baugé
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Laure Maneix
Journal articles
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Deciphering chondrocyte behaviour in matrix-induced autologous chondrocyte implantation to undergo accurate cartilage repair with hyaline matrix
M. Demoor
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L. Maneix
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D. Ollitrault
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F. Legendre
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E. Duval
Journal articles
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Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes
Emmanuelle Renard
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Benoît Porée
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Christos Chadjichristos
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Magdalini Kypriotou
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Laure Maneix
Journal articles
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Décryptage des signalisations moléculaires contrôlant la différenciation des chondrocytes : retombées pour l’ingénierie tissulaire du cartilage : le projet ANR-TecSan PROMOCART
S. Claus
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E. Aubert-Foucher
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E. Perrier-Groult
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C. Bougault
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M.-C. Ronzière
Journal articles
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Interleukin-1 and Transforming Growth Factor-ß 1 as Crucial Factors in Osteoarthritic Cartilage Metabolism
Jean-Pierre Pujol
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Christos Chadjichristos
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Florence Legendre
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Catherine Baugé
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Gallic Beauchef
Journal articles
hal-03838453v1
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Rhein, the metabolite of diacerhein, reduces the proliferation of osteoarthritic chondrocytes and synoviocytes without inducing apoptosis
F. Legendre
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A. Heuze
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K. Boukerrouche
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S. Leclercq
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K. Boumediene
Journal articles
hal-04200456v1
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Interleukin-6 (IL-6) and/or Soluble IL-6 Receptor Down-regulation of Human Type II Collagen Gene Expression in Articular Chondrocytes Requires a Decrease of Sp1·Sp3 Ratio and of the Binding Activity of Both Factors to the COL2A1 Promoter
Benoît Porée
,
Magdalini Kypriotou
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Christos Chadjichristos
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Gallic Beauchef
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Emmanuelle Renard
Journal articles
hal-03838464v1
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Chondroitin sulfate modulation of matrix and inflammatory gene expression in IL-1β-stimulated chondrocytes – study in hypoxic alginate bead cultures
F. Legendre
,
C. Baugé
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R. Roche
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A.S. Saurel
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J.P. Pujol
Journal articles
hal-04200519v1
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Evaluation of Adhesion, Proliferation, and Functional Differentiation of Dermal Fibroblasts on Glycosaminoglycan-Coated Polysulfone Membranes
Joan Attia
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Florence Legendre
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Quang Trong Nguyen
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Catherine Baugé
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Karim Boumediene
Journal articles
hal-04200472v1
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Interleukin-1β impairment of transforming growth factor β1 signaling by DOWN-REGULATION of transforming growth factor β receptor type II and up-regulation of Smad7 in human articular chondrocytes
C. Baugé
,
F. Legendre
,
S. Leclercq
,
J. Elissalde
,
J. Pujol
Journal articles
hal-04200583v1
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Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways.
F Legendre
,
P Bogdanowicz
,
G Martin
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F Domagala
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S Leclercq
Clinical and experimental rheumatology, 2007, 25 (4), pp.546-55
Journal articles
hal-04200554v1
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Role of interleukin 6 (IL-6)/IL-6R-induced signal tranducers and activators of transcription and mitogen-activated protein kinase/extracellular.
Florence Legendre
,
Patrick Bogdanowicz
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Karim Boumediene
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Jean-Pierre Pujol
Journal of Rheumatology, 2005, 32 (7), pp.1307-16
Journal articles
hal-04201771v1
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Comparative effects of 2 antioxidants, selenomethionine and epigallocatechin-gallate, on catabolic and anabolic gene expression of articular chondrocytes.
Rina Andriamanalijaona
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Madeleine Kypriotou
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Catherine Baugé
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Emmanuelle Renard
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Florence Legendre
Journal of Rheumatology, 2005, 32 (10), pp.1958-67
Journal articles
hal-04200629v1
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JAK/STAT but Not ERK1/ERK2 Pathway Mediates Interleukin (IL)-6/Soluble IL-6R Down-regulation of Type II Collagen, Aggrecan Core, and Link Protein Transcription in Articular Chondrocytes
Florence Legendre
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Jayesh Dudhia
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Jean-Pierre Pujol
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Patrick Bogdanowicz
Journal articles
hal-04201804v1
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