Florence Siepmann

71
Documents

Publications

Publications

Microencapsulation of the probiotic Bifidobacterium longum by spray-drying: Formulation and process optimisation

Vita d'Amico , Florence Siepmann , Juergen Siepmann , Christel Neut , Nunzio Denora et al.
Journal of Drug Delivery Science and Technology, 2026, 115, pp.107670. ⟨10.1016/j.jddst.2025.107670⟩
Article dans une revue hal-05468089 v1
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Release mechanisms of PLGA microparticles prepared using a microfluidics device or a beaker

L. A. Lefol , A. Sodano , P. Bawuah , J. A. Zeitler , F. Danede et al.
International Journal of Pharmaceutics: X, 2025, International Journal of Pharmaceutics: X, 10, ⟨10.1016/j.ijpx.2025.100366⟩
Article dans une revue hal-05248215 v1
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Perilymph sampling in Mongolian gerbil, technical note and procedure evaluation.

Claire Olivier , Cyril Beck , Mickaël Risoud , Pierre-Emmanuel Lemesre , Juergen Siepmann et al.
Hearing Research, 2025, Hearing Research, 458, pp.109188. ⟨10.1016/j.heares.2025.109188⟩
Article dans une revue hal-04965672 v1
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Release mechanisms of PLGA-based drug delivery systems: A review

J. Siepmann , Florence Siepmann
International Journal of Pharmaceutics: X, 2025, 10, pp.100440. ⟨10.1016/j.ijpx.2025.100440⟩
Article dans une revue hal-05468220 v1
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Drug release from PLGA microparticles can be slowed down by a surrounding hydrogel.

Lise-Anne Lefol , Prince Bawuah , J. Axel Zeitler , Jérémy Verin , Florence Danede et al.
International Journal of Pharmaceutics: X, 2024, International Journal of Pharmaceutics: X, 6, pp.100220. ⟨10.1016/j.ijpx.2023.100220⟩
Article dans une revue hal-04477038 v1

Poly(D,l-lactide-co-glycolide) particles are metabolised by the gut microbiome and elevate short chain fatty acids.

L. E. Mccoubrey , Fabiana Ferraro , N. Seegobin , Jérémy Verin , H. A. Alfassam et al.
Journal of Controlled Release, 2024, Journal of Controlled Release, 369, pp.163-178. ⟨10.1016/j.jconrel.2024.03.039⟩
Article dans une revue hal-04591667 v1
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EVA implants for controlled drug delivery to the inner ear

Y. Bedulho das Lages , N. Milanino , J. Verin , Jean-François Willart , Florence Danede et al.
International Journal of Pharmaceutics: X, 2024, International Journal of Pharmaceutics: X, 8, pp.100271. ⟨10.1016/j.ijpx.2024.100271⟩
Article dans une revue hal-04690008 v1
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Machine learning of Raman spectra predicts drug release from polysaccharide coatings for targeted colonic delivery

Youssef Abdalla , Laura Mccoubrey , Fabiana Ferraro , Lisa Sonnleitner , Yannick Guinet et al.
Journal of Controlled Release, 2024, Journal of Controlled Release, 374, pp.103-111. ⟨10.1016/j.jconrel.2024.08.010⟩
Article dans une revue hal-04687027 v1
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In-situ forming PLGA implants: Towards less toxic solvents.

F. Ramos , Jean-François Willart , Christel Neut , Kevimy Agossa , Juergen Siepmann et al.
International Journal of Pharmaceutics: X, 2024, International Journal of Pharmaceutics: X, 657, pp.124121. ⟨10.1016/j.ijpharm.2024.124121⟩
Article dans une revue hal-04591703 v1
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Colon targeting in rats, dogs and IBD patients with species-independent film coatings

Fabiana Ferraro , Lisa Sonnleitner , Christel Neut , Séverine Mahieux , Jérémy Verin et al.
International Journal of Pharmaceutics: X, 2024, International Journal of Pharmaceutics: X, 7, pp.100233. ⟨10.1016/j.ijpx.2024.100233⟩
Article dans une revue hal-04504251 v1
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Release of liposomes from hyaluronic acid-based hybrid systems: Effects of liposome surface and size

Céline Jaudoin , Maria Maue Gehrke , Isabelle Grillo , Fabrice Cousin , Malika Ouldali et al.
International Journal of Pharmaceutics, 2023, 648, pp.123560. ⟨10.1016/j.ijpharm.2023.123560⟩
Article dans une revue hal-04589294 v1
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Silicone matrices for controlled dexamethasone release: toward a better understanding of the underlying mass transport mechanisms.

T. Rongthong , Adam Qnouch , M. Maue Gehrke , Laurent Paccou , P. Oliveira et al.
Regenerative Biomaterials, 2023, Regenerative Biomaterials, 10, pp.rbad008. ⟨10.1093/rb/rbad008⟩
Article dans une revue hal-04067392 v1

Thermo-responsive Diels-Alder stabilized hydrogels for ocular drug delivery of a corticosteroid and an anti-VEGF fab fragment.

Blessing C. Ilochonwu , Simone A. van der Lugt , Ada Annala , Greta Di Marco , Thibault Sampon et al.
Journal of Controlled Release, 2023, Journal of Controlled Release, 361, pp.334-349. ⟨10.1016/j.jconrel.2023.07.052⟩
Article dans une revue hal-04477153 v1
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3D printed PLGA implants: APF DDM vs. FDM

C. Bassand , L. Benabed , Sébastien Charlon , J. Verin , J. Freitag et al.
Journal of Controlled Release, 2023, 353, pp.864-874. ⟨10.1016/j.jconrel.2022.11.052⟩
Article dans une revue hal-04301963 v1
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3D printed PLGA implants: How the filling density affects drug release

C. Bassand , F. Siepmann , L. Benabed , J. Verin , J. Freitag et al.
Journal of Controlled Release, 2023, Journal of Controlled Release, 363, pp.1-11. ⟨10.1016/j.jconrel.2023.09.020⟩
Article dans une revue hal-04301938 v1
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Exploration of the physical states of riboflavin (free base) by mechanical milling

Charline Henaff , Juergen Siepmann , Florence Siepmann , Florence Danede , Marie-Noëlle Avettand-Fènoël et al.
International Journal of Pharmaceutics, 2023, International journal of pharmaceutics, 645, pp.123416. ⟨10.1016/j.ijpharm.2023.123416⟩
Article dans une revue hal-04214667 v1
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PLGA implants for controlled dexamethasone delivery: Impact of the polymer chemistry

S. Wachowiak , Florence Danede , Jean-François Willart , Florence Siepmann , Juergen Siepmann et al.
Journal of Drug Delivery Science and Technology, 2023, Journal of Drug Delivery Science and Technology, 86, pp.104648. ⟨10.1016/j.jddst.2023.104648⟩
Article dans une revue hal-04297225 v3
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In Vitro and In Vivo Evaluation of a pH-, Microbiota- and Time-Based Oral Delivery Platform for Colonic Release

S. Moutaharrik , A. Maroni , Christel Neut , Caroline Dubuquoy , Laurent Dubuquoy et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, 2022, Eur J Pharm Biopharm, 183, pp.13-23. ⟨10.1016/j.ejpb.2022.12.013⟩
Article dans une revue hal-04013724 v1
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Effect of Lactobacillus reuteri on Gingival Inflammation and Composition of the Oral Microbiota in Patients Undergoing Treatment with Fixed Orthodontic Appliances: Study Protocol of a Randomized Control Trial

K. Agossa , M. Dubar , G. Lemaire , A. Blaizot , C. Catteau et al.
Pathogens, 2022, 11 (2), pp.112. ⟨10.3390/pathogens11020112⟩
Article dans une revue hal-03557370 v1
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Hot melt extruded PLGA implants loaded with ibuprofen: How heat exposure alters the physical drug state

C. Bassand , L. Benabed , J. Verin , Florence Danede , L.A. Lefol et al.
Journal of Drug Delivery Science and Technology, 2022, 73, pp.103432. ⟨10.1016/j.jddst.2022.103432⟩
Article dans une revue hal-03813259 v2
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How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up

Celine Bassand , L. Benabed , J. Freitag , Jérémy Verin , Florence Siepmann et al.
International Journal of Pharmaceutics: X, 2022, International Journal of Pharmaceutics: X, 4, pp.100131. ⟨10.1016/j.ijpx.2022.100131⟩
Article dans une revue hal-04010203 v1
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How agarose gels surrounding plga implants limit swelling and slow down drug release

Celine Bassand , Jérémy Verin , M. Lamatsch , Florence Siepmann , Juergen Siepmann
Journal of Controlled Release, 2022, Journal of Controlled Release, 343, pp.255-266. ⟨10.1016/j.jconrel.2022.01.028⟩
Article dans une revue hal-04461626 v1
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PLGA implants for controlled drug release: Impact of the diameter

Celine Bassand , J. Freitag , L. Benabed , Jérémy Verin , Florence Siepmann et al.
European Journal of Pharmaceutics and Biopharmaceutics, 2022, European Journal of Pharmaceutics and Biopharmaceutics, 177, pp.50-60. ⟨10.1016/j.ejpb.2022.05.020⟩
Article dans une revue hal-04009128 v1
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Long term behavior of dexamethasone-loaded cochlear implants: In vitro & in vivo

T. Rongthong , Adam Qnouch , M. M. Gehrke , Florence Danede , Jean-François Willart et al.
International Journal of Pharmaceutics: X, 2022, International Journal of Pharmaceutics: X, 4, pp.100141. ⟨10.1016/j.ijpx.2022.100141⟩
Article dans une revue hal-04013479 v1

Antimicrobial effect and physical properties of an injectable \"active oxygen\" gel for the treatment of periodontitis.

Kadiatou Sy , Joséphine Flamme , Héloïse Maquet , Feng Chai , Christel Nuet et al.
Journal- American College of Dentists, 2021, Journal- American College of Dentists, 33 (6), pp.305-309
Article dans une revue hal-04000395 v1
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PEO hot melt extrudates for controlled drug delivery: Importance of the type of drug and loading

Oriane Cantin , Florence Siepmann , Jean-François Willart , Florence Danede , Juergen Siepmann et al.
Journal of Drug Delivery Science and Technology, 2021, 61, pp.102238. ⟨10.1016/j.jddst.2020.102238⟩
Article dans une revue hal-03023791 v1

Oral colon delivery platform based on a novel combination approach: design concept and preliminary evaluation

Saliha Moutaharrik , Alessandra Maroni , Alice Melocchi , Lucia Zema , Anastasia Foppoli et al.
Journal of Drug Delivery Science and Technology, 2021, Journal of Drug Delivery Science and Technology, 66, pp.102919. ⟨10.1016/j.jddst.2021.102919⟩
Article dans une revue hal-04457827 v1
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Injection-molded capsule bodies and caps based on polymer blends for controlled drug delivery

Youcef Benzine , Florence Siepmann , Christel Neut , Florence Danede , Jean-François Willart et al.
European Journal of Pharmaceutics and Biopharmaceutics, 2021, 168, pp.1-14. ⟨10.1016/j.ejpb.2021.08.007⟩
Article dans une revue hal-03814465 v1

In-situ forming drug-delivery systems for periodontal treatment: current knowledge and perspectives

Marie Dubar , Martin Lizambard , Elisabeth Delcourt-Debruyne , Fareeha Batool , Olivier Huck et al.
Biomedical Materials, 2021, 16 (6), ⟨10.1088/1748-605X/ac254c⟩
Article dans une revue hal-04003165 v1
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Mechanistic explanation of the (up to) 3 release phases of plga microparticles: monolithic dispersions studied at lower temperatures

Fahima Tamani , Celine Bassand , Mounira Hamoudi , Florence Siepmann , Juergen Siepmann
International Journal of Pharmaceutics, 2021, International Journal of Pharmaceutics, 596, pp.120220. ⟨10.1016/j.ijpharm.2021.120220⟩
Article dans une revue hal-04457733 v1
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Dexamethasone-loaded cochlear implants: How to provide a desired “burst release”

Adam Qnouch , V. Solarczyk , J. Verin , G. Tourrel , P. Stahl et al.
International Journal of Pharmaceutics: X, 2021, 3, pp.100088. ⟨10.1016/j.ijpx.2021.100088⟩
Article dans une revue hal-03326831 v1

Clinical translation of advanced colonic drug delivery technologies

Atheer Awad , Christine M. Madla , Laura E. Mccoubrey , Fabiana Ferraro , Francesca K. H. Gavins et al.
Advanced drug delivery reviews, 2021, Advanced Drug Delivery Reviews, 181, pp.114076. ⟨10.1016/j.addr.2021.114076⟩
Article dans une revue (article de synthèse) hal-04462343 v1
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Towards a Better Understanding of Verapamil Release from Kollicoat SR:IR Coated Pellets Using Non-Invasive Analytical Tools

Julie Fahier , Branko Vukosavljevic , Laure de Kinder , Hugues Florin , Jean-Francois Goossens et al.
Pharmaceutics, 2021, Pharmaceutics, 13 (10), pp.1723. ⟨10.3390/pharmaceutics13101723⟩
Article dans une revue hal-03621350 v1
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Structure determination of riboflavin by synchrotron high-resolution powder X-ray diffraction

Mathieu Guerain , Frédéric Affouard , Charline Henaff , Catherine Dejoie , Florence Danede et al.
Acta Crystallographica Section C : Structural Chemistry [2014-..], 2021, 77 (12), pp.800-806. ⟨10.1107/s2053229621012171⟩
Article dans une revue hal-03469379 v1
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Antibiotic use in periodontal therapy among french dentists and factors which influence prescribing practices

Kevimy Agossa , Kadiatou Sy , Theo Mainville , Marjolaine Gosset , Sylvie Jeanne et al.
Antibiotics (Basel, Switzerland), 2021, Antibiotics (Basel, Switzerland), 10 (3), pp.303. ⟨10.3390/antibiotics10030303⟩
Article dans une revue hal-03844792 v1
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Antibiotic Use in Periodontal Therapy among French Dentists and Factors Which Influence Prescribing Practices

Kevimy Agossa , Kadiatou Sy , Théo Mainville , Marjolaine Gosset , Sylvie Jeanne et al.
Antibiotics, 2021, 10 (3), pp.303. ⟨10.3390/antibiotics10030303⟩
Article dans une revue hal-04914163 v1
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How Adding Chlorhexidine or Metallic Nanoparticles Affects the Antimicrobial Performance of Calcium Hydroxide Paste as an Intracanal Medication: An In Vitro Study.

Kadiatou Sy , Kevimy Agossa , Mickaël Maton , Henry Chijcheapaza-Flores , Bernard Martel et al.
Antibiotics (Basel, Switzerland), 2021, Antibiotics (Basel), 10 (11), pp.1352. ⟨10.3390/antibiotics10111352⟩
Article dans une revue hal-04000149 v1
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Starch-based controlled release matrix tablets: impact of the type of starch

Dhouha Elgaied-Lamouchi , Nicolas Descamps , Philippe Lefevre , Isabelle Rambur , Jean-Yves Pierquin et al.
Journal of Drug Delivery Science and Technology, 2021, Journal of Drug Delivery Science and Technology, 61, ⟨10.1016/j.jddst.2020.102152⟩
Article dans une revue hal-04459147 v1

Eudragit rl-based film coatings: how to minimize sticking and adjust drug release using mas

Thitiphorn Rongthong , Srisagul Sungthongjeen , Florence Siepmann , Juergen Siepmann , Thaned Pongjanyakul
European Journal of Pharmaceutics and Biopharmaceutics, 2020, European Journal of Pharmaceutics and Biopharmaceutics, ⟨10.1016/j.ejpb.2020.01.011⟩
Article dans une revue hal-04409650 v1
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In-situ forming implants for dual controlled release of chlorhexidine and ibuprofen for periodontitis treatment: Microbiological and mechanical key properties

K. Agossa , A. Delepierre , M. Lizambard , E. Delcourt-Debruyne , J. Siepmann et al.
Journal of Drug Delivery Science and Technology, 2020, 60, pp.101956 -. ⟨10.1016/j.jddst.2020.101956⟩
Article dans une revue hal-03491488 v1
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Robustness of controlled release tablets based on a cross-linked pregelatinized potato starch matrix

Dhouha Elgaied , N. Descamps , P. Lefevre , Asta Rahama Mackin Mohamour , Christel Neut et al.
AAPS PharmSciTech, 2020, AAPS PharmSciTech, 21, pp.148. ⟨10.1208/s12249-020-01674-4⟩
Article dans une revue hal-04470181 v1
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Injection molded capsules for colon delivery combining time-controlled and enzyme-triggered approaches

Federica Casati , Alice Melocchi , Saliha Moutaharrik , Marco Uboldi , Anastasia Foppoli et al.
International Journal of Molecular Sciences, 2020, 21 (6), pp.1917. ⟨10.3390/ijms21061917⟩
Article dans une revue hal-03120143 v1

Sink conditions do not guarantee the absence of saturation effects

Juergen Siepmann , Florence Siepmann
International Journal of Pharmaceutics, 2020, International Journal of Pharmaceutics, 577, pp.119009. ⟨10.1016/j.ijpharm.2019.119009⟩
Article dans une revue hal-04457790 v1
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Controlled release tablets based on HPMC:lactose blends

E. Moussa , F. Siepmann , M.P. Flament , Y. Benzine , F. Penz et al.
Journal of Drug Delivery Science and Technology, 2019, 52, pp.607 - 617. ⟨10.1016/j.jddst.2019.05.028⟩
Article dans une revue hal-03486328 v1
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Hot melt extruded polysaccharide blends for controlled drug delivery

Youcef Benzine , Florence Siepmann , Christel Neut , Florence Danede , Jean-François Willart et al.
Journal of Drug Delivery Science and Technology, 2019, Journal of Drug Delivery Science and Technology, 54, pp.101317. ⟨10.1016/j.jddst.2019.101317⟩
Article dans une revue hal-03007398 v2

In-situ forming implants for the treatment of periodontal diseases: Simultaneous controlled release of an antiseptic and an anti-inflammatory drug

M. Lizambard , T. Menu , M. Fossart , C. Bassand , K. Agossa et al.
International Journal of Pharmaceutics, 2019, 572, pp.118833. ⟨10.1016/j.ijpharm.2019.118833⟩
Article dans une revue hal-03079869 v1
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Mechanistic explanation of the (up to) 3 release phases of PLGA microparticles: Diprophylline dispersions

F. Tamani , C. Bassand , M. Hamoudi-Ben Yelles , F. Danède , Jean-François Willart et al.
International Journal of Pharmaceutics, 2019, pp.118819. ⟨10.1016/j.ijpharm.2019.118819⟩
Article dans une revue hal-02363521 v1
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In-situ forming implants loaded with chlorhexidine and ibuprofen for periodontal treatment: Proof of concept study in vivo

Fareeha Batool , Kevimy Agossa , Martin Lizambard , Catherine Petit , Isaac Maximiliano Bugueno et al.
International Journal of Pharmaceutics, 2019, 569, pp.118564 -. ⟨10.1016/j.ijpharm.2019.118564⟩
Article dans une revue hal-03488176 v1
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Coloring of PLGA implants to better understand the underlying drug release mechanisms

C. Bode , H. Kranz , F. Siepmann , J. Siepmann
International Journal of Pharmaceutics, 2019, 569, pp.118563 -. ⟨10.1016/j.ijpharm.2019.118563⟩
Article dans une revue hal-03488183 v1
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In-situ forming PLGA implants: How additives affect swelling and drug release

C. Bode , H. Kranz , A. Kruszka , F. Siepmann , J. Siepmann
Journal of Drug Delivery Science and Technology, 2019, 53, pp.101180 -. ⟨10.1016/j.jddst.2019.101180⟩
Article dans une revue hal-03487519 v1
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Often neglected: PLGA/PLA swelling orchestrates drug release: HME implants

C. Bode , H. Kranz , A. Fivez , F. Siepmann , J. Siepmann
Journal of Controlled Release, 2019, 306, pp.97 - 107. ⟨10.1016/j.jconrel.2019.05.039⟩
Article dans une revue hal-03485867 v1
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Towards a better understanding of the release mechanisms of caffeine from PLGA microparticles

Fahima Tamani , Mounira Cherifa Hamoudi , Florence Danede , Jean‐françois Willart , Florence Siepmann et al.
Journal of Applied Polymer Science, 2019, pp.48710. ⟨10.1002/app.48710⟩
Article dans une revue hal-02369150 v1
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When drugs plasticize film coatings: Unusual formulation effects observed with metoprolol and Eudragit RS

Youness Karrout , Florence Siepmann , Youcef Benzine , Laurent Paccou , Yannick Guinet et al.
International Journal of Pharmaceutics, 2018, International journal of pharmaceutics, 539 (1-2), pp.39-49. ⟨10.1016/j.ijpharm.2018.01.014⟩
Article dans une revue hal-03358400 v2
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In-situ forming plga implants for intraocular dexamethasone delivery

C. Bode , Heiko Kranz , Florence Siepmann , Juergen Siepmann
International Journal of Pharmaceutics, 2018, International Journal of Pharmaceutics, 548, pp.337-348. ⟨10.1016/j.ijpharm.2018.07.013⟩
Article dans une revue hal-04467257 v1

Using Milling To Explore Physical States: The Amorphous and Polymorphic Forms of Dexamethasone

Paulo F. M. Oliveira , Jean-François Willart , Juergen Siepmann , Florence Siepmann , Marc Descamps
Crystal Growth & Design, 2018, Crystal Growth & Design, 18, pp.1748-1757. ⟨10.1021/acs.cgd.7b01664⟩
Article dans une revue hal-02333436 v1
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Hybrid ear cubes for local controlled dexamethasone delivery to the inner ear

Maria Maue Gehrke , Jérémy Verin , Dan Gnansia , Guillaume Tourrel , Michael Risoud et al.
European journal of pharmaceutical sciences official journal of the European Federation for Pharmaceutical Sciences, 2018, European journal of pharmaceutical sciences official journal of the European Federation for Pharmaceutical Sciences, 126, pp.23-32. ⟨10.1016/j.ejps.2018.04.045⟩
Article dans une revue hal-04467276 v2

Crystalline Polymorphism Emerging From a Milling-Induced Amorphous Form: The Case of Chlorhexidine Dihydrochloride

Elena Elisei , Jean-François Willart , Florence Danede , Juergen Siepmann , Florence Siepmann et al.
Journal of Pharmaceutical Sciences, 2018, Journal of Pharmaceutical Sciences, 107, pp.121-126. ⟨10.1016/j.xphs.2017.07.003⟩
Article dans une revue hal-02332954 v1

Physical key properties of antibiotic-free, PLGA/HPMC-based in-situ forming implants for local periodontitis treatment

Kevimy Agossa , M. Lizambard , T. Rongthong , Elisabeth Delcourt Debruyne , Juergen Siepmann et al.
International Journal of Pharmaceutics, 2017, International Journal of Pharmaceutics, 521, pp.282-293. ⟨10.1016/j.ijpharm.2017.02.039⟩
Article dans une revue istex hal-03994275 v1

Amorphous chlorhexidine (free base) dissolves less rapidly compared to crystalline

Charline Henaff , Juergen Siepmann , Florence Siepmann , Jean-François Willart
14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2024, Vienne (Austria), Austria
Poster de conférence hal-04512566 v1

EVA implants for controlled drug delivery to the inner ear

Yanis Bedulho das Lages , N. Milanino , Jérémy Verin , Jean-François Willart , Florence Danede et al.
14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2024, Vienne (Austria), Austria
Poster de conférence hal-04510764 v1

Solid state amorphization of Chlorhexidine chlorhexidine upon milling

Charline Henaff , Juergen Siepmann , Florence Siepmann , Jean-François Willart
16th PSSRC: Pharmaceutical Solid State Research Cluster, 2021, Helsinki, Finland
Poster de conférence hal-04516322 v1

Solid state amorphization of riboflavin upon milling

Charline Henaff , Juergen Siepmann , Florence Siepmann , Jean-François Willart
15th PSSRC: Pharmaceutical Solid State Research Cluster, 2021, Online, France
Poster de conférence hal-04544926 v1

Silicone matrices for controlled drug delivery to the inner ear: Effects of the drug form and agglomerates

T Rongthong , M. Gehrke , P Oliveira , Florence Danede , Jean-François Willart et al.
11th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical technology, Mar 2018, Granada, Spain
Poster de conférence hal-02333507 v1

How single PLGA microparticles behave

Fahima Tamani , Celine Bassand , M Hamoudi-Ben Yelles , Jean-François Willart , Florence Danede et al.
3rd European Conference on Pharmaceutics, Mar 2018, Bologne, Italy
Poster de conférence hal-02333470 v1

Homogeneity, drug release and swelling of dexamethasone loaded cochlear implants

M. Gehrke , T. Rongthong , G. Tourrel , D. Gnansia , P Oliveira et al.
11th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical technology, Mar 2018, Granada, Spain
Poster de conférence hal-02333487 v1

Amorphization and solubility enhancement: the peculiar case of chlorhexidine free base

Charline Henaff , Juergen Siepmann , Florence Siepmann , Jean-François Willart
17th PSSRC: Pharmaceutical Solid State Research Cluster, 2023, Cambridge (GB), United Kingdom
Communication dans un congrès hal-04509160 v1

Exploration du polymorphisme de la riboflavine par broyage mécanique

Charline Henaff , Juergen Siepmann , Florence Siepmann , Jean-François Willart
Conférence International Matériaux 2022, 2022, Lille, France
Communication dans un congrès hal-04509166 v1

Solid state transformations of pharmaceuticals induced by milling: Experimental and numerical kinetics investigations

Jean-François Willart , Pierre Bordet , Pauline Martinetto , Emeline Dudognon , Juergen Siepmann et al.
INCOME 2020 (9th International Conference on Mechanochemistry and Mechanical Alloying, 2020, Cagliari, Italy
Communication dans un congrès hal-04512512 v1

Swelling Controlled Drug Delivery Systems

Juergen Siepmann , Florence Siepmann
Siepmann, Juergen; Siegel, Ronald A.; Rathbone, Michael J. Fundamentals and Applications of Controlled Release Drug Delivery, Springer Link, pp.153-170, 2019, 978-1-4614-0881-9. ⟨10.1007/978-1-4614-0881-9_7⟩
Chapitre d'ouvrage hal-04474610 v1

Diffusion Controlled Drug Delivery Systems

Juergen Siepmann , Ronald A. Siegel , Florence Siepmann
Siepmann, Juergen; Siegel, Ronald A.; Rathbone, Michael J. Fundamentals and Applications of Controlled Release Drug Delivery, -, Springer Link, pp.127-152, 2019, 978-1-4614-0881-9. ⟨10.1007/978-1-4614-0881-9_6⟩
Chapitre d'ouvrage hal-04474666 v1

Time-Controlled Drug Delivery Systems

Juergen Siepmann , Florence Siepmann
Modern Pharmaceutics, Volume 2, Taylor & Francis Group, pp.1-22, 2010, 9780429148293
Chapitre d'ouvrage hal-04408849 v1