Francesca Fiorini

21
Documents

Publications

Publications

Lyon, at the center of the global virology research challenge

Hélène Dutartre , Francesca Fiorini , Denis Gerlier , Henri Gruffat , Patrick Lomonte et al.
Virologie, 2025, 29 (2), pp.59-63. ⟨10.1684/vir.2025.1078⟩
Article dans une revue hal-05310565 v1
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The SARS-CoV-2 nucleocapsid protein interferes with the full enzymatic activation of UPF1 and its interaction with UPF2

Veronica Nuccetelli , Makram Mghezzi-Habellah , Séverine Deymier , Armelle Roisin , Francine Gérard-Baraggia et al.
Nucleic Acids Research, 2025, 53 (2), pp.gkaf010. ⟨10.1093/nar/gkaf010⟩
Article dans une revue hal-04913926 v1

La défense de l’envahisseur

Vincent Mocquet , Francesca Fiorini
Médecine/Sciences, 2025, 41 (10), pp.740-742. ⟨10.1051/medsci/2025159⟩
Article dans une revue hal-05383439 v1
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Microtubule remodeling by the innate immune factor Trim69 compromises dynein-dependent migration of HIV virion cores toward the nucleus

Charlotte Vadon , Xuan-Nhi Nguyen , Valerie Siahaan , Yuxin Song , Arya Krishnan et al.
Proceedings of the National Academy of Sciences of the United States of America, 2025, 122 (41), pp.e2505128122. ⟨10.1073/pnas.2505128122⟩
Article dans une revue hal-05367711 v1

RNA at the crossroads of structure, function, and disease

Didier Auboeuf , Cyril Bourgeois , Francesca Fiorini , Virginie Marcel
Article dans une revue hal-05306217 v1
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Stable structures or PABP1 loading protects cellular and viral RNAs against ISG20-mediated decay

Camille Louvat , Séverine Deymier , Xuan-Nhi Nguyen , Emmanuel Labaronne , Kodie Noy et al.
Life Science Alliance, 2024, 7 (5), pp.e202302233. ⟨10.26508/lsa.202302233⟩
Article dans une revue hal-04609421 v1
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The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding

Cecilia Rocchi , Camille Louvat , Adriana Miele , Julien Batisse , Christophe Guillon et al.
International Journal of Molecular Sciences, 2022, 23 (22), pp.13742. ⟨10.3390/ijms232213742⟩
Article dans une revue hal-03434126 v1
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The C-Terminal Domain of HIV-1 Integrase: A Swiss Army Knife for the Virus?

Cecilia Rocchi , Patrice Gouet , Vincent Parissi , Francesca Fiorini
Viruses, 2022, 14 (7), pp.1397. ⟨10.3390/v14071397⟩
Article dans une revue hal-03733732 v1
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ISG20: an enigmatic antiviral RNase targeting multiple viruses

Séverine Deymier , Camille Louvat , Francesca Fiorini , Andrea Cimarelli
FEBS Open Bio, 2022, 12 (6), pp.1096-1111. ⟨10.1002/2211-5463.13382⟩
Article dans une revue hal-03859392 v1
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In vitro, in cellulo and structural characterizations of the interaction between the integrase of Porcine Endogenous Retrovirus A/C and proteins of the BET family

Kathy Gallay , Guillaume Blot , Margaux Chahpazoff , Halima Yajjou-Hamalian , Marie-Pierre Confort et al.
Virology, 2019, 532, pp.69-81. ⟨10.1016/j.virol.2019.04.002⟩
Article dans une revue hal-02359028 v1
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Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase

Eric Mauro , Paul Lesbats , Delphine Lapaillerie , Stéphane Chaignepain , Benoit Maillot et al.
Nucleic Acids Research, 2019, 47 (7), pp.3607-3618. ⟨10.1093/nar/gkz091⟩
Article dans une revue hal-02122315 v1
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HTLV-1 Tax plugs and freezes UPF1 helicase leading to nonsense-mediated mRNA decay inhibition

Francesca Fiorini , Jean-Philippe Robin , Joanne Kanaan , Malgorzata Borowiak , Vincent Croquette et al.
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-017-02793-6⟩
Article dans une revue hal-02358887 v1
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A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner

Manjeera Gowravaram , Fabien Bonneau , Joanne Kanaan , Vincent D Maciej , Francesca Fiorini et al.
Nucleic Acids Research, 2018, 46 (5), pp.2648 - 2659. ⟨10.1093/nar/gky040⟩
Article dans une revue hal-01762546 v1

A mechanistic study of helicases with magnetic traps

Samar Hodeib , Saurabh Raj , Maria Manosas , Weiting Zhang , Debjani Bagchi et al.
Protein Science, 2017, 26 (7), pp.1314-1336. ⟨10.1002/pro.3187⟩
Article dans une revue hal-02358906 v1
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Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activities

Francesca Fiorini , Debjani Bagchi , Hervé Le Hir , Vincent Croquette
Nature Communications, 2015, 6 (1), pp.7581. ⟨10.1038/ncomms8581⟩
Article dans une revue hal-02358918 v1

Tight intramolecular regulation of the human Upf1 helicase by its N- and C-terminal domains

Francesca Fiorini , Marc Boudvillain , Hervé Le Hir
Nucleic Acids Research, 2013, 41 (4), pp.2404-2415. ⟨10.1093/nar/gks1320⟩
Article dans une revue hal-02358926 v1

Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly

Isabelle Barbosa , Nazmul Haque , Francesca Fiorini , Charlotte Barrandon , Catherine Tomasetto et al.
Nature Structural and Molecular Biology, 2012, 19 (10), pp.983-990. ⟨10.1038/nsmb.2380⟩
Article dans une revue istex hal-02358933 v1

Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and Its Regulation by Upf2

Sutapa Chakrabarti , Uma Jayachandran , Fabien Bonneau , Francesca Fiorini , Claire Basquin et al.
Molecular Cell, 2011, 41 (6), pp.693-703. ⟨10.1016/j.molcel.2011.02.010⟩
Article dans une revue hal-02358974 v1

Recognition of heptameric seed sequence underlies multi-target regulation by RybB small RNA in Salmonella enterica

Roberto Balbontín , Francesca Fiorini , Nara Figueroa-Bossi , Josep Casadesús , Lionello Bossi
Molecular Microbiology, 2010, 78 (2), pp.380-394. ⟨10.1111/j.1365-2958.2010.07342.x⟩
Article dans une revue hal-02359004 v1